首页 > 最新文献

2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)最新文献

英文 中文
Design Considerations for Ground Referencing in Multi - Module Neural Implants 多模块神经植入物接地参考的设计考虑
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584708
Dorian Haci, Yan Liu, S. Ghoreishizadeh, T. Constandinou
Implantable neural interfaces have evolved in the past decades from stimulation-only devices to closed-loop recording and stimulation systems, allowing both for more targeted therapeutic techniques and more advanced prosthetic implants. Emerging applications require multi-module active implantable devices with intrabody power and data transmission. This distributed approach poses a new set of challenges related to inter-module connectivity, functional reliability and patient safety. This paper addresses the ground referencing challenge in active multi-implant systems, with a particular focus on neural recording devices. Three different grounding schemes (passive, drive, and sense) are presented and evaluated in terms of both recording reliability and patient safety. Considerations on the practical implementation of body potential referencing circuitry are finally discussed, with a detailed analysis of their impact on the recording performance.
在过去的几十年里,植入式神经接口已经从仅刺激设备发展到闭环记录和刺激系统,允许更有针对性的治疗技术和更先进的假体植入物。新兴应用需要具有体内电源和数据传输功能的多模块有源植入式设备。这种分布式方法提出了一系列与模块间连接、功能可靠性和患者安全相关的新挑战。本文解决了主动多植入系统中的地面参考挑战,特别关注神经记录设备。提出了三种不同的接地方案(被动、驱动和感应),并在记录可靠性和患者安全性方面进行了评估。最后讨论了实际实现人体电位参考电路的考虑因素,并详细分析了它们对记录性能的影响。
{"title":"Design Considerations for Ground Referencing in Multi - Module Neural Implants","authors":"Dorian Haci, Yan Liu, S. Ghoreishizadeh, T. Constandinou","doi":"10.1109/BIOCAS.2018.8584708","DOIUrl":"https://doi.org/10.1109/BIOCAS.2018.8584708","url":null,"abstract":"Implantable neural interfaces have evolved in the past decades from stimulation-only devices to closed-loop recording and stimulation systems, allowing both for more targeted therapeutic techniques and more advanced prosthetic implants. Emerging applications require multi-module active implantable devices with intrabody power and data transmission. This distributed approach poses a new set of challenges related to inter-module connectivity, functional reliability and patient safety. This paper addresses the ground referencing challenge in active multi-implant systems, with a particular focus on neural recording devices. Three different grounding schemes (passive, drive, and sense) are presented and evaluated in terms of both recording reliability and patient safety. Considerations on the practical implementation of body potential referencing circuitry are finally discussed, with a detailed analysis of their impact on the recording performance.","PeriodicalId":259162,"journal":{"name":"2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114988008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Embedded Classification of Local Field Potentials Recorded from Rat Barrel Cortex with Implanted Multi-Electrode Array 植入多电极阵列记录大鼠脑皮层局部场电位的嵌入分类
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584830
Xiaying Wang, M. Magno, L. Cavigelli, M. Mahmud, C. Cecchetto, S. Vassanelli, L. Benini
This paper focuses on ultra-low power embedded classification of neural activities. The machine learning (ML) algorithm has been trained using evoked local field potentials (LFPs) recorded with an implanted 16×16 multi-electrode array (MEA) from the rat barrel cortex while stimulating the whisker. Experimental results demonstrate that ML can be successfully applied to noisy single-trial LFPs. We achieved up to 95.8% test accuracy in predicting the whisker deflection. The trained ML model is successfully implemented on a low-power embedded system with an average consumption of 2.6 mW.
本文主要研究超低功耗嵌入式神经活动分类。机器学习(ML)算法通过植入16×16多电极阵列(MEA)记录的局部诱发场电位(LFPs)来训练,同时刺激大鼠桶状皮层的须。实验结果表明,机器学习可以成功地应用于有噪声的单次lfp。我们在预测晶须偏转方面达到95.8%的测试准确度。训练后的机器学习模型在平均功耗为2.6 mW的低功耗嵌入式系统上成功实现。
{"title":"Embedded Classification of Local Field Potentials Recorded from Rat Barrel Cortex with Implanted Multi-Electrode Array","authors":"Xiaying Wang, M. Magno, L. Cavigelli, M. Mahmud, C. Cecchetto, S. Vassanelli, L. Benini","doi":"10.1109/BIOCAS.2018.8584830","DOIUrl":"https://doi.org/10.1109/BIOCAS.2018.8584830","url":null,"abstract":"This paper focuses on ultra-low power embedded classification of neural activities. The machine learning (ML) algorithm has been trained using evoked local field potentials (LFPs) recorded with an implanted 16×16 multi-electrode array (MEA) from the rat barrel cortex while stimulating the whisker. Experimental results demonstrate that ML can be successfully applied to noisy single-trial LFPs. We achieved up to 95.8% test accuracy in predicting the whisker deflection. The trained ML model is successfully implemented on a low-power embedded system with an average consumption of 2.6 mW.","PeriodicalId":259162,"journal":{"name":"2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129459650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Ultra-High-Resolution Millimeter-Wave Imaging: A New Promising Skin Cancer Imaging Modality 超高分辨率毫米波成像:一种新的有前途的皮肤癌成像方式
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584772
Amir Mirbeik-Sabzevari, Negar Tavassolian, R. Ashinoff
The goal of this study is to investigate the feasibility of using millimeter-wave imaging as a new medical imaging modality for the detection of skin cancer at early stages. In a recent large-scale study, the authors have demonstrated that statistically considerable contrasts exist between the millimeter-wave dielectric properties of normal skin and skin cancer tissues. In this work, an imaging system with a record-wide bandwidth of 98 GHz was developed using the synthetic ultra-wideband millimeterwave imaging approach, a new ultra-high-resolution imaging technique recently developed by the authors. Ex-vivo imaging experiments were conducted on two freshly-excised malignant skin tissues obtained from skin cancer patients having undergone Mohs micrographic surgeries at Hackensack University Medical Center. A programmable measurement platform was designed to automatically scan the tissues across a rectangular aperture plane. Furthermore, a novel frequency-domain imaging algorithm was developed to process the recorded signals and generate an image of the cancerous tissue. The obtained images correctly identified the tumor locations as verified by Mohs histological evaluations.
本研究的目的是探讨毫米波成像作为一种新的医学成像方式在早期检测皮肤癌的可行性。在最近的一项大规模研究中,作者已经证明,正常皮肤和皮肤癌组织的毫米波介电特性之间存在统计学上相当大的差异。在这项工作中,利用作者最近开发的一种新的超高分辨率成像技术——合成超宽带毫米波成像方法,开发了一个记录带宽为98 GHz的成像系统。对在哈肯萨克大学医学中心接受莫氏显微摄影手术的皮肤癌患者新近切除的两个恶性皮肤组织进行了离体成像实验。设计了一个可编程的测量平台,通过矩形孔径平面对组织进行自动扫描。此外,开发了一种新的频域成像算法来处理记录的信号并生成癌组织的图像。获得的图像正确地识别肿瘤位置,并通过Mohs组织学评估验证。
{"title":"Ultra-High-Resolution Millimeter-Wave Imaging: A New Promising Skin Cancer Imaging Modality","authors":"Amir Mirbeik-Sabzevari, Negar Tavassolian, R. Ashinoff","doi":"10.1109/BIOCAS.2018.8584772","DOIUrl":"https://doi.org/10.1109/BIOCAS.2018.8584772","url":null,"abstract":"The goal of this study is to investigate the feasibility of using millimeter-wave imaging as a new medical imaging modality for the detection of skin cancer at early stages. In a recent large-scale study, the authors have demonstrated that statistically considerable contrasts exist between the millimeter-wave dielectric properties of normal skin and skin cancer tissues. In this work, an imaging system with a record-wide bandwidth of 98 GHz was developed using the synthetic ultra-wideband millimeterwave imaging approach, a new ultra-high-resolution imaging technique recently developed by the authors. Ex-vivo imaging experiments were conducted on two freshly-excised malignant skin tissues obtained from skin cancer patients having undergone Mohs micrographic surgeries at Hackensack University Medical Center. A programmable measurement platform was designed to automatically scan the tissues across a rectangular aperture plane. Furthermore, a novel frequency-domain imaging algorithm was developed to process the recorded signals and generate an image of the cancerous tissue. The obtained images correctly identified the tumor locations as verified by Mohs histological evaluations.","PeriodicalId":259162,"journal":{"name":"2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128336424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Spur Gears and Leadscrew Based, Efficient and Flexible Infusion System Design 基于正齿轮和丝杠的高效灵活的输液系统设计
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584685
Muhammad Rizwan Khan, M. Tariq, Farasat Munir, Muhammad Awais Bin Altaf
This paper presents the design of an inexpensive infusion system for low and middle-income countries like Pakistan. A flexible improvised design in terms of accuracy and user-interface is presented, based on spur gears and leadscrew. The trade-offs between accuracy and other design parameters such as weight, cost and size are also discussed. A detailed analysis of accuracy dependence on leadscrew pitch and number of teeth of each gear is given. Two prototypes are presented, with and without gearbox. An android application is developed considering widespread use of smartphones. It provides access to internet making it easy to share the data. Several alarms and feedback components have also been added to the system. Final design is efficient in terms of number of hardware components, robustness, portability, cost, power and size achieving an accuracy of 23.7nL per step of the stepper motor with 20cc reservoir.
本文为巴基斯坦等中低收入国家设计了一种廉价的输注系统。提出了一种基于正齿轮和丝杠的高精度、灵活的简易设计方法。还讨论了精度和其他设计参数(如重量、成本和尺寸)之间的权衡。详细分析了螺杆节距和各齿轮齿数对精度的影响。提出了两种原型,带和不带变速箱。考虑到智能手机的广泛使用,开发了android应用程序。它提供了互联网访问,使数据共享变得容易。系统中还增加了几个告警和反馈组件。最终设计在硬件组件数量,稳健性,便携性,成本,功率和尺寸方面是有效的,实现了20cc储层的步进电机每步23.7nL的精度。
{"title":"Spur Gears and Leadscrew Based, Efficient and Flexible Infusion System Design","authors":"Muhammad Rizwan Khan, M. Tariq, Farasat Munir, Muhammad Awais Bin Altaf","doi":"10.1109/BIOCAS.2018.8584685","DOIUrl":"https://doi.org/10.1109/BIOCAS.2018.8584685","url":null,"abstract":"This paper presents the design of an inexpensive infusion system for low and middle-income countries like Pakistan. A flexible improvised design in terms of accuracy and user-interface is presented, based on spur gears and leadscrew. The trade-offs between accuracy and other design parameters such as weight, cost and size are also discussed. A detailed analysis of accuracy dependence on leadscrew pitch and number of teeth of each gear is given. Two prototypes are presented, with and without gearbox. An android application is developed considering widespread use of smartphones. It provides access to internet making it easy to share the data. Several alarms and feedback components have also been added to the system. Final design is efficient in terms of number of hardware components, robustness, portability, cost, power and size achieving an accuracy of 23.7nL per step of the stepper motor with 20cc reservoir.","PeriodicalId":259162,"journal":{"name":"2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128534963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Like Kleenex for Wearables: A soft, strong and disposable ECG monitoring system 像可穿戴设备的Kleenex:一个柔软,强大和一次性的心电监测系统
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584778
Y. Bhagat, Patrick Vcrdon, S. Avuthu, D. Parsons, M. Sussman, G. Wable, R. Hugeneck
Although electrocardiography (ECG) monitoring systems have been available in the form of wearable patches for the better part of two decades, they are limited in their ability to be utilized as inexpensive, yet vital short-term measurement devices that are (truly) completely disposable. Advancing current practices in soft conformable electronics, we present a Bluetooth-enabled, fully disposable single-lead ECG patch comprising inkjet printed Ag-AgCl electrodes and components integrated on a single, flexible hybrid printed circuit board with an average current consumption of 3.6 mA from a 3.0 V stack of four flexible Lithium polymer batteries. As part of the Live Demonstration, our goals are to showcase the patch's functionality including real-time continuous ECG display and fall detection, and the flexible enclosures and adhesives conferring its unique softness, strength and disposability following a 7-day lifespan.
虽然心电图(ECG)监测系统已经以可穿戴贴片的形式出现了近二十年,但它们作为廉价的短期测量设备的使用能力有限,而且(真正的)完全是一次性的。我们提出了一种支持蓝牙的、完全一次性的单导联ECG贴片,该贴片包括喷墨印刷Ag-AgCl电极和集成在单个柔性混合印刷电路板上的组件,来自4个柔性锂聚合物电池3.0 V堆叠的平均电流消耗为3.6 mA。作为现场演示的一部分,我们的目标是展示贴片的功能,包括实时连续ECG显示和跌倒检测,以及柔性外壳和粘合剂,赋予其独特的柔软性,强度和一次性,使用寿命为7天。
{"title":"Like Kleenex for Wearables: A soft, strong and disposable ECG monitoring system","authors":"Y. Bhagat, Patrick Vcrdon, S. Avuthu, D. Parsons, M. Sussman, G. Wable, R. Hugeneck","doi":"10.1109/BIOCAS.2018.8584778","DOIUrl":"https://doi.org/10.1109/BIOCAS.2018.8584778","url":null,"abstract":"Although electrocardiography (ECG) monitoring systems have been available in the form of wearable patches for the better part of two decades, they are limited in their ability to be utilized as inexpensive, yet vital short-term measurement devices that are (truly) completely disposable. Advancing current practices in soft conformable electronics, we present a Bluetooth-enabled, fully disposable single-lead ECG patch comprising inkjet printed Ag-AgCl electrodes and components integrated on a single, flexible hybrid printed circuit board with an average current consumption of 3.6 mA from a 3.0 V stack of four flexible Lithium polymer batteries. As part of the Live Demonstration, our goals are to showcase the patch's functionality including real-time continuous ECG display and fall detection, and the flexible enclosures and adhesives conferring its unique softness, strength and disposability following a 7-day lifespan.","PeriodicalId":259162,"journal":{"name":"2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129631543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Battery-Free. Sticker-Like, Device for Health Monitoring, Operated by Optical Power Transfer Battery-Free。类似贴纸的健康监测装置,由光功率传输操作
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584707
W. Nattakarn, M. Haruta, T. Noda, K. Sasagawa, T. Tokuda, M. Sawan, S. Carrara, J. Ohta
This work presents the concept of a battery-free, sticker-like, device for a non-invasive health-monitoring sensor. The device consists of two functional blocks: an optical power-transfer block and an amperometric measurement block. The former accumulates power from a series-connected photovoltaic cell in a capacitor and intermittently supplies the power to the amperometric measurement circuit. This circuit is driven by powering pulses and displays the amperometric current as the durations of the light pulses from a light-emitting diode. The function of the circuit was successfully demonstrated through simulations, in which the equivalent circuit of an electrochemical glucose sensor was used as an example. The simulation results showed that the proposed device would work as expected for a variety of glucose concentrations at an oxidation voltage of 0.8 V.
这项工作提出了一种无电池,类似贴纸的设备的概念,用于非侵入性健康监测传感器。该装置由两个功能块组成:光功率传输块和安培测量块。前者在电容器中积累来自串联光伏电池的功率,并间歇性地向安培测量电路供电。该电路由功率脉冲驱动,并将安培电流显示为发光二极管发出的光脉冲的持续时间。以电化学葡萄糖传感器等效电路为例,通过仿真验证了该电路的功能。仿真结果表明,在氧化电压为0.8 V的情况下,所提出的器件可以在各种葡萄糖浓度下正常工作。
{"title":"Battery-Free. Sticker-Like, Device for Health Monitoring, Operated by Optical Power Transfer","authors":"W. Nattakarn, M. Haruta, T. Noda, K. Sasagawa, T. Tokuda, M. Sawan, S. Carrara, J. Ohta","doi":"10.1109/BIOCAS.2018.8584707","DOIUrl":"https://doi.org/10.1109/BIOCAS.2018.8584707","url":null,"abstract":"This work presents the concept of a battery-free, sticker-like, device for a non-invasive health-monitoring sensor. The device consists of two functional blocks: an optical power-transfer block and an amperometric measurement block. The former accumulates power from a series-connected photovoltaic cell in a capacitor and intermittently supplies the power to the amperometric measurement circuit. This circuit is driven by powering pulses and displays the amperometric current as the durations of the light pulses from a light-emitting diode. The function of the circuit was successfully demonstrated through simulations, in which the equivalent circuit of an electrochemical glucose sensor was used as an example. The simulation results showed that the proposed device would work as expected for a variety of glucose concentrations at an oxidation voltage of 0.8 V.","PeriodicalId":259162,"journal":{"name":"2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129988065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The Challenges of Designing an Inductively Coupled Power Link for μm-sized On-Chip Coils μm级片上线圈电感耦合电源链路设计的挑战
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584781
A. Khalifa, Yasha Karimi, Yuanfei Huang, M. Stanaćević, R. Etienne-Cummings
This paper highlights the challenges which exist in realizing miniaturized inductively powered devices that integrate μm-sized coils. As the amount of energy harvested is directly proportional to the effective area of the receiver coil, ultra-small coils receive very limited power and thus need to be carefully optimized for a particular application. Apart from the geometric design of the coil, there are also many other factors that impact the maximum amount of energy that can be harvested on a μm-sized coil. These unique challenges are discussed and addressed in this work using a fully integrated wireless power receiver fabricated in GF 130 nm CMOS 8RF technology. The entire system measures 300 × 300 μm2and is wirelessly powered at 1.18 GHz.
本文强调了在实现集成μm大小线圈的小型电感供电器件中存在的挑战。由于收获的能量与接收线圈的有效面积成正比,因此超小型线圈接收的功率非常有限,因此需要针对特定应用进行仔细优化。除了线圈的几何设计外,还有许多其他因素影响μm大小的线圈可以收集的最大能量。本文采用GF 130 nm CMOS 8RF技术制造的全集成无线电源接收器,讨论并解决了这些独特的挑战。整个系统的尺寸为300 × 300 μm2,无线供电频率为1.18 GHz。
{"title":"The Challenges of Designing an Inductively Coupled Power Link for μm-sized On-Chip Coils","authors":"A. Khalifa, Yasha Karimi, Yuanfei Huang, M. Stanaćević, R. Etienne-Cummings","doi":"10.1109/BIOCAS.2018.8584781","DOIUrl":"https://doi.org/10.1109/BIOCAS.2018.8584781","url":null,"abstract":"This paper highlights the challenges which exist in realizing miniaturized inductively powered devices that integrate μm-sized coils. As the amount of energy harvested is directly proportional to the effective area of the receiver coil, ultra-small coils receive very limited power and thus need to be carefully optimized for a particular application. Apart from the geometric design of the coil, there are also many other factors that impact the maximum amount of energy that can be harvested on a μm-sized coil. These unique challenges are discussed and addressed in this work using a fully integrated wireless power receiver fabricated in GF 130 nm CMOS 8RF technology. The entire system measures 300 × 300 μm2and is wirelessly powered at 1.18 GHz.","PeriodicalId":259162,"journal":{"name":"2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132511591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Robust Wireless Power Transfer to Multiple mm-Scale Freely-Positioned Neural Implants 多毫米尺度自由定位神经植入物的强大无线电力传输
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584730
Peilong Feng, T. Constandinou
This paper presents a novel wireless power transfer (WPT) scheme that consists of a two-tier hierarchy of near-field inductively coupled links. Key aims are to provide efficient power transfer efficiency (PTE) and uniform energy distribution for mm-scale free-positioned neural implants. The top tier facilitates a transcutaneous link from a scalp-worn (em-scale) primary coil to a subcutaneous array of smaller, parallel-connected secondary coils. These are then wired through the skull to a corresponding set of parallel connected primary coils in the lower tier, placed epidurally. These then inductively couple to freely positioned (mm-scale) secondary coils within each subdural implant. This architecture has three key advantages: (1) the opportunity to achieve efficient energy transfer by utilising two short-distance inductive links; (2) good uniformity of the transdural power distribution through the multiple (redundant) coils; and (3) a reduced risk of infection by maintaining the dura protecting the blood-brain barrier. The functionality of this approach has been verified and optimised through HFSS simulations, to demonstrate the robustness against positional and angular misalignment. The average 11.9% PTE and 26.6% power distribution deviation (PDD) have been achieved for the Rx coil in parallel with the epidural coil array. The average PTE and PDD degenerate to 2.6% and 62.8% when the Rx coil is perpendicular to the epidural coil array.
本文提出了一种新的无线电力传输(WPT)方案,该方案由两层近场电感耦合链路组成。关键目标是为毫米尺度自由定位神经植入物提供高效的能量传输效率(PTE)和均匀的能量分布。顶层便于从头皮佩戴(em级)初级线圈到较小的、并联的次级线圈的皮下阵列的经皮连接。然后将这些线圈通过颅骨连接到下层相应的一组平行连接的主线圈上,置于硬膜外。然后电感耦合到每个硬膜下植入物内自由定位的(毫米级)次级线圈。该架构具有三个关键优势:(1)利用两个短距离感应链路实现高效能量传输的机会;(2)通过多个(冗余)线圈的跨硬膜功率分配均匀性好;(3)通过维持保护血脑屏障的硬脑膜,降低感染风险。通过HFSS仿真验证和优化了该方法的功能,以证明其对位置和角度失调的鲁棒性。Rx线圈与硬膜外线圈阵列并联时,平均PTE为11.9%,PDD为26.6%。当Rx线圈垂直于硬膜外线圈阵列时,平均PTE和PDD分别降至2.6%和62.8%。
{"title":"Robust Wireless Power Transfer to Multiple mm-Scale Freely-Positioned Neural Implants","authors":"Peilong Feng, T. Constandinou","doi":"10.1109/BIOCAS.2018.8584730","DOIUrl":"https://doi.org/10.1109/BIOCAS.2018.8584730","url":null,"abstract":"This paper presents a novel wireless power transfer (WPT) scheme that consists of a two-tier hierarchy of near-field inductively coupled links. Key aims are to provide efficient power transfer efficiency (PTE) and uniform energy distribution for mm-scale free-positioned neural implants. The top tier facilitates a transcutaneous link from a scalp-worn (em-scale) primary coil to a subcutaneous array of smaller, parallel-connected secondary coils. These are then wired through the skull to a corresponding set of parallel connected primary coils in the lower tier, placed epidurally. These then inductively couple to freely positioned (mm-scale) secondary coils within each subdural implant. This architecture has three key advantages: (1) the opportunity to achieve efficient energy transfer by utilising two short-distance inductive links; (2) good uniformity of the transdural power distribution through the multiple (redundant) coils; and (3) a reduced risk of infection by maintaining the dura protecting the blood-brain barrier. The functionality of this approach has been verified and optimised through HFSS simulations, to demonstrate the robustness against positional and angular misalignment. The average 11.9% PTE and 26.6% power distribution deviation (PDD) have been achieved for the Rx coil in parallel with the epidural coil array. The average PTE and PDD degenerate to 2.6% and 62.8% when the Rx coil is perpendicular to the epidural coil array.","PeriodicalId":259162,"journal":{"name":"2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130797172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
A 3.51µW 0.31µVrms Biofuel Cell Enabled Integrated Analog CMOS Front-End in 130 nm CMOS 一个3.51µW 0.31µVrms生物燃料电池支持集成模拟CMOS前端在130纳米CMOS
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584700
Huan Hu, Tanzila Islam, Chung-Ching Lin, A. Kostyukova, S. Ha, Subhanshu Gupta
Biofuel cell as an efficient energy converter is a promising biocompatible technology which harvests the blood glucose into usable electrical energy and replaces the toxic lithium-based battery solutions. However, the promise of this perennial non-toxic power system is tempered by its unstable operation and low-voltage outputs leading to very limited operational lifetimes. This paper demonstrates a glucose powered analog front-end with superior noise performance, which is enabled by a standalone enzymatic biofuel cell operating for more than 30 min on active power without replenishment. Two biofuel cells are stacked to realize 0.5V output using commercially available glucose oxidase and the enzyme stability is improved via multipoint protein crosslinks by glutaraldehyde. An integrated piezo-resistive analog front-end is demonstrated including cascaded dual-supply amplifier with a successive approximation register (SAR-ADC) and single-opamp relaxation oscillator occupying 1.12mm2• A switched-resistor biasing scheme using on-chip duty-cycled clock is proposed achieving measured input-referred noise of only $0.31mu mathrm{V}_{mathrm{RMS}}$. The proposed hybrid power scheme uses $1.61mu mathrm{W}$ from the battery with 1.9 µW provided by the biofuel cell. Measured results show on-chip gain and noise variations across temperature of only 1.1 dB and $19.2 nV/sqrt{Hz}$ respectively with noise (power) efficient factor of of 1.46 (1.63).
生物燃料电池作为一种高效的能量转换器,是一种很有前途的生物相容性技术,它可以将血糖转化为可用的电能,取代有毒的锂基电池。然而,由于其不稳定的运行和低压输出导致非常有限的运行寿命,这种长期无毒电力系统的前景受到了影响。本文演示了一种具有优越噪声性能的葡萄糖驱动模拟前端,它由独立的酶生物燃料电池在有功功率下运行超过30分钟而无需补充。利用市售的葡萄糖氧化酶,将两个生物燃料电池堆叠在一起,实现0.5V输出,并通过戊二醛的多点蛋白质交联提高酶的稳定性。演示了一种集成压阻模拟前端,包括带连续逼近寄存器(SAR-ADC)的级联双电源放大器和占用1.12mm2的单opamp弛豫振荡器。提出了一种使用片上占空比时钟的开关电阻偏置方案,可实现测量的输入参考噪声仅为$0.31mu mathrm{V}_{mathrm{RMS}}$。提出的混合动力方案使用来自电池的$1.61mu mathrm{W}$和由生物燃料电池提供的1.9 μ W。测量结果表明,片上增益和噪声随温度的变化分别仅为1.1 dB和$19.2 nV/sqrt{Hz}$,噪声(功率)效率系数为1.46(1.63)。
{"title":"A 3.51µW 0.31µVrms Biofuel Cell Enabled Integrated Analog CMOS Front-End in 130 nm CMOS","authors":"Huan Hu, Tanzila Islam, Chung-Ching Lin, A. Kostyukova, S. Ha, Subhanshu Gupta","doi":"10.1109/BIOCAS.2018.8584700","DOIUrl":"https://doi.org/10.1109/BIOCAS.2018.8584700","url":null,"abstract":"Biofuel cell as an efficient energy converter is a promising biocompatible technology which harvests the blood glucose into usable electrical energy and replaces the toxic lithium-based battery solutions. However, the promise of this perennial non-toxic power system is tempered by its unstable operation and low-voltage outputs leading to very limited operational lifetimes. This paper demonstrates a glucose powered analog front-end with superior noise performance, which is enabled by a standalone enzymatic biofuel cell operating for more than 30 min on active power without replenishment. Two biofuel cells are stacked to realize 0.5V output using commercially available glucose oxidase and the enzyme stability is improved via multipoint protein crosslinks by glutaraldehyde. An integrated piezo-resistive analog front-end is demonstrated including cascaded dual-supply amplifier with a successive approximation register (SAR-ADC) and single-opamp relaxation oscillator occupying 1.12mm2• A switched-resistor biasing scheme using on-chip duty-cycled clock is proposed achieving measured input-referred noise of only $0.31mu mathrm{V}_{mathrm{RMS}}$. The proposed hybrid power scheme uses $1.61mu mathrm{W}$ from the battery with 1.9 µW provided by the biofuel cell. Measured results show on-chip gain and noise variations across temperature of only 1.1 dB and $19.2 nV/sqrt{Hz}$ respectively with noise (power) efficient factor of of 1.46 (1.63).","PeriodicalId":259162,"journal":{"name":"2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128798909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rakeness-based Compressed Sensing of Surface ElectroMyoGraphy for Improved Hand Movement Recognition in the Compressed Domain 基于rakenness的表面肌电压缩感知在压缩域改进手部运动识别
Pub Date : 2018-10-01 DOI: 10.1109/BIOCAS.2018.8584763
Alex Marchioni, Mauro Mangia, Fabio Pareschi, R. Rovatti, G. Setti
Surface electromyography (sEMG) waveforms are widely used to generate control signals in several application areas, ranging from prosthetic to consumer electronics. Classically, such waveforms are acquired at Nyquist rate and digitally transmitted trough a wireless channel to a decision/actuation node. This causes large energy consumption and is incompatible with the implementation of ultra-low power acquisition nodes. We already proposed Compressed Sensing (CS) as a low-complexity method to achieve substantial energy saving by reducing the size of data to be transmitted while preserving the information content. We here make a significant leap forward by showing that hand movements recognition task can be performed directly in the compressed domain with a success rate greater than 98 % and with a reduction of the number of transmitted bits by two order of magnitude with respect to row data.
表面肌电图(sEMG)波形被广泛用于产生控制信号的几个应用领域,从假肢到消费电子产品。通常,这种波形以奈奎斯特速率获取,并通过无线信道数字传输到决策/驱动节点。这导致能耗大,与超低功耗采集节点的实现不兼容。我们已经提出压缩感知(CS)作为一种低复杂度的方法,通过减少要传输的数据的大小,同时保持信息的内容来实现大量的节能。我们在这里取得了重大的飞跃,证明了手动作识别任务可以直接在压缩域中执行,成功率大于98%,并且传输的比特数相对于行数据减少了两个数量级。
{"title":"Rakeness-based Compressed Sensing of Surface ElectroMyoGraphy for Improved Hand Movement Recognition in the Compressed Domain","authors":"Alex Marchioni, Mauro Mangia, Fabio Pareschi, R. Rovatti, G. Setti","doi":"10.1109/BIOCAS.2018.8584763","DOIUrl":"https://doi.org/10.1109/BIOCAS.2018.8584763","url":null,"abstract":"Surface electromyography (sEMG) waveforms are widely used to generate control signals in several application areas, ranging from prosthetic to consumer electronics. Classically, such waveforms are acquired at Nyquist rate and digitally transmitted trough a wireless channel to a decision/actuation node. This causes large energy consumption and is incompatible with the implementation of ultra-low power acquisition nodes. We already proposed Compressed Sensing (CS) as a low-complexity method to achieve substantial energy saving by reducing the size of data to be transmitted while preserving the information content. We here make a significant leap forward by showing that hand movements recognition task can be performed directly in the compressed domain with a success rate greater than 98 % and with a reduction of the number of transmitted bits by two order of magnitude with respect to row data.","PeriodicalId":259162,"journal":{"name":"2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125423295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
期刊
2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1