首页 > 最新文献

2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG)最新文献

英文 中文
On producing customised soft-tissue prostheses using digital tools and silicone casting techniques 关于使用数字工具和硅胶铸造技术生产定制的软组织假体
Pub Date : 2015-02-01 DOI: 10.1109/ENBENG.2015.7088831
M. Couto, M. Machado, R. Neto
Summary form only given. Physical and emotional problems can be prominent whenever a significant loss of a critical part of the face or body (e.g., nose, ears, eyes and fingers) is involved. Resulting from neoplasms, congenital malformations, burns, trauma, among others, the solution for these external defects, whenever a surgical reconstruction is impractical or counter-indicated, are conventionally addressed by an anaplastologist, who produces customised prostheses throughout a manual and time-consuming procedure via lifecasting techniques. Currently, advances on computational technologies have given rise to a digital-based method. This approach is used herein for the design and fabrication of personalised silicone prostheses. In this work, an efficient and cost-effective manufacturing methodology, able to produce accurate prostheses with a high-resolution level (e.g. wrinkles, fingerprints) is proposed. This framework entails six tasks: (i) data acquisition, (ii) 3D reconstruction, (iii) prosthesis design, (iv) mould fabrication, (v) prosthesis manufacturing and, (vi) final fittings [1]. First, regarding data acquisition, two technologies are taken into consideration, namely medical imaging or 3D scanning photometry. After the 3D reconstruction, for the prosthesis design, 3D measuring and design operations are carried out in an STL editor. This provides modelling tools targeting a good fitting between the surface models of the failing part and symmetric or donor organ. Also, a main issue to be addressed in this step is the fixation system, which is fundamental to ensure a good prosthesis retention. Following, a SLA-prototype is fabricated and the mould is produced via silicone casting. The prosthesis manufacturing is performed using pigmented silicon considering patient's skin tone. Nails, hair and/or extrinsic coloration may be include in order to accomplish a more realistic appearance of the prosthesis. The proposed approach showed encouraging outcomes, providing a comfortable solution, reducing the processing time, and disclosing excellent aesthetic results [1].
只提供摘要形式。每当涉及面部或身体的重要部位(如鼻子、耳朵、眼睛和手指)的重大损失时,身体和情绪问题就会突出。由于肿瘤、先天性畸形、烧伤、创伤等原因造成的这些外部缺陷的解决方案,无论何时外科重建不切实际或有反指症,通常都由整形医生来解决,他们通过生命铸造技术生产定制的假体,整个过程都是手工和耗时的。目前,计算技术的进步已经产生了一种基于数字的方法。此方法用于设计和制造个性化硅胶假体。在这项工作中,提出了一种高效且具有成本效益的制造方法,能够生产具有高分辨率水平(例如皱纹,指纹)的精确假肢。该框架需要六个任务:(i)数据采集,(ii) 3D重建,(iii)假体设计,(iv)模具制造,(v)假体制造和(vi)最终配件[1]。首先,在数据获取方面,考虑了两种技术,即医学成像或3D扫描光度法。三维重建完成后,在STL编辑器中进行三维测量和设计操作。这提供了针对失败部分和对称或供体器官的表面模型之间良好拟合的建模工具。此外,在这一步中需要解决的一个主要问题是固定系统,这是确保良好假体固位的基础。接下来,制作了一个sla原型,并通过硅树脂铸造生产了模具。考虑到患者的肤色,假体的制造使用有色硅。指甲、头发和/或外部着色可以包括在内,以实现更真实的假体外观。所提出的方法显示了令人鼓舞的结果,提供了舒适的解决方案,减少了处理时间,并揭示了出色的美学效果[1]。
{"title":"On producing customised soft-tissue prostheses using digital tools and silicone casting techniques","authors":"M. Couto, M. Machado, R. Neto","doi":"10.1109/ENBENG.2015.7088831","DOIUrl":"https://doi.org/10.1109/ENBENG.2015.7088831","url":null,"abstract":"Summary form only given. Physical and emotional problems can be prominent whenever a significant loss of a critical part of the face or body (e.g., nose, ears, eyes and fingers) is involved. Resulting from neoplasms, congenital malformations, burns, trauma, among others, the solution for these external defects, whenever a surgical reconstruction is impractical or counter-indicated, are conventionally addressed by an anaplastologist, who produces customised prostheses throughout a manual and time-consuming procedure via lifecasting techniques. Currently, advances on computational technologies have given rise to a digital-based method. This approach is used herein for the design and fabrication of personalised silicone prostheses. In this work, an efficient and cost-effective manufacturing methodology, able to produce accurate prostheses with a high-resolution level (e.g. wrinkles, fingerprints) is proposed. This framework entails six tasks: (i) data acquisition, (ii) 3D reconstruction, (iii) prosthesis design, (iv) mould fabrication, (v) prosthesis manufacturing and, (vi) final fittings [1]. First, regarding data acquisition, two technologies are taken into consideration, namely medical imaging or 3D scanning photometry. After the 3D reconstruction, for the prosthesis design, 3D measuring and design operations are carried out in an STL editor. This provides modelling tools targeting a good fitting between the surface models of the failing part and symmetric or donor organ. Also, a main issue to be addressed in this step is the fixation system, which is fundamental to ensure a good prosthesis retention. Following, a SLA-prototype is fabricated and the mould is produced via silicone casting. The prosthesis manufacturing is performed using pigmented silicon considering patient's skin tone. Nails, hair and/or extrinsic coloration may be include in order to accomplish a more realistic appearance of the prosthesis. The proposed approach showed encouraging outcomes, providing a comfortable solution, reducing the processing time, and disclosing excellent aesthetic results [1].","PeriodicalId":285567,"journal":{"name":"2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG)","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125446643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using an inverse method for optimizing the material constants of the Mooney-Rivlin constitutive model 用逆方法优化Mooney-Rivlin本构模型的材料常数
Pub Date : 2015-02-01 DOI: 10.1109/ENBENG.2015.7088862
Elisabete Silva, M. Parente, R. Jorge, T. Mascarenhas
The pelvic floor is made up of a set of soft tissue structures, supported by a network of muscles, which are in turn attached to each other and to the pelvis by condensations of fascial and fibromuscular tissues [1]. For clinical, technical and ethical reasons it is not possible to obtain the properties of these soft tissues in vivo. The utilization of Inverse Method is therefore required in order to obtain estimates for the mechanical properties of these structures. In this work, an optimization algorithm was implemented in order to obtain the optimal mechanical constants for the Mooney-Rivlin constitutive model [2]. The optimization algorithm uses the python scripting language to couple the Matlab® and Abaqus® software. The Powell's method was used for the optimization part of the algorithm.
骨盆底由一组软组织结构组成,由肌肉网络支撑,肌肉网络通过筋膜和纤维肌肉组织的凝聚相互连接并与骨盆相连[1]。由于临床、技术和伦理原因,不可能在体内获得这些软组织的特性。因此,需要利用逆法对这些结构的力学性能进行估计。为了获得Mooney-Rivlin本构模型的最优力学常数[2],本文实现了一种优化算法。优化算法采用python脚本语言对Matlab®和Abaqus®软件进行耦合。算法的优化部分采用了鲍威尔方法。
{"title":"Using an inverse method for optimizing the material constants of the Mooney-Rivlin constitutive model","authors":"Elisabete Silva, M. Parente, R. Jorge, T. Mascarenhas","doi":"10.1109/ENBENG.2015.7088862","DOIUrl":"https://doi.org/10.1109/ENBENG.2015.7088862","url":null,"abstract":"The pelvic floor is made up of a set of soft tissue structures, supported by a network of muscles, which are in turn attached to each other and to the pelvis by condensations of fascial and fibromuscular tissues [1]. For clinical, technical and ethical reasons it is not possible to obtain the properties of these soft tissues in vivo. The utilization of Inverse Method is therefore required in order to obtain estimates for the mechanical properties of these structures. In this work, an optimization algorithm was implemented in order to obtain the optimal mechanical constants for the Mooney-Rivlin constitutive model [2]. The optimization algorithm uses the python scripting language to couple the Matlab® and Abaqus® software. The Powell's method was used for the optimization part of the algorithm.","PeriodicalId":285567,"journal":{"name":"2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG)","volume":"203 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126016964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
3D liver segmentation in computed tomography and positron emission tomography exams through active surfaces 通过活动表面的计算机断层扫描和正电子发射断层扫描检查中的三维肝脏分割
Pub Date : 2015-02-01 DOI: 10.1109/ENBENG.2015.7088895
D. Mendes, N. Ferreira, J. Silva, F. Caramelo
In the medical field, the segmentation of organs and structures in the patient's body is a very important task to assist the study of morphological and pathological changes of organs. Normally, specialists perform manual segmentation, however it is time consuming, error-prone and observer-dependent. Here the experience of the expertise influences the quality of the ultimate results. This work aims to develop tools for automatic liver segmentation using data acquired with two medical imaging modalities: Computed Tomography and Positron Emission Tomography, in order to improve the way of obtaining volumes of object and to help the clinician in the study of the organ. Liver segmentation methods were developed for each modality separately and also for the combination of the two modalities. To validate the implemented algorithms, specialists delineated some images for each exam. The results of segmentation algorithms were then compared with the expert reference. The outputs obtained are reasonable and a good starting point for further work.
在医学领域,对患者体内的器官和结构进行分割是辅助研究器官形态和病理变化的一项非常重要的任务。通常情况下,专家执行手动分割,但这是耗时的,容易出错的,并且依赖于观察者。在这里,专家的经验会影响最终结果的质量。本研究旨在利用计算机断层扫描和正电子发射断层扫描两种医学成像方式获得的数据,开发自动肝脏分割工具,以改进获得物体体积的方法,并帮助临床医生研究器官。针对每一种模式分别开发了肝脏分割方法,也为两种模式的结合开发了肝脏分割方法。为了验证实现的算法,专家们为每个考试描绘了一些图像。然后将分割算法的结果与专家参考进行比较。所得结果合理,为进一步的工作奠定了良好的基础。
{"title":"3D liver segmentation in computed tomography and positron emission tomography exams through active surfaces","authors":"D. Mendes, N. Ferreira, J. Silva, F. Caramelo","doi":"10.1109/ENBENG.2015.7088895","DOIUrl":"https://doi.org/10.1109/ENBENG.2015.7088895","url":null,"abstract":"In the medical field, the segmentation of organs and structures in the patient's body is a very important task to assist the study of morphological and pathological changes of organs. Normally, specialists perform manual segmentation, however it is time consuming, error-prone and observer-dependent. Here the experience of the expertise influences the quality of the ultimate results. This work aims to develop tools for automatic liver segmentation using data acquired with two medical imaging modalities: Computed Tomography and Positron Emission Tomography, in order to improve the way of obtaining volumes of object and to help the clinician in the study of the organ. Liver segmentation methods were developed for each modality separately and also for the combination of the two modalities. To validate the implemented algorithms, specialists delineated some images for each exam. The results of segmentation algorithms were then compared with the expert reference. The outputs obtained are reasonable and a good starting point for further work.","PeriodicalId":285567,"journal":{"name":"2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127868036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Analysis of multiple sclerosis DTI images that uses tract based spatial statistics 基于区域空间统计的多发性硬化DTI图像分析
Pub Date : 2015-02-01 DOI: 10.1109/ENBENG.2015.7088839
J. Oliveira, M. Castelo‐Branco, Ricardo Morais, S. Baptista, João Pereira
Multiple Sclerosis is a demyelinating disease affecting the communication in the central nervous system. Magnetic resonance diffusion imaging provides information about water diffusion in white matter and allows an early detection of abnormalities, comparing to conventional magnetic resonance techniques. The aim of this study is to find out which the brain regions that are damaged during disease progression. Tract-Based Spatial Statistics is a voxelwise multi-subject statistical analysis which performs non-linear registration of each subject's image and projects them onto an alignment-invariant tract representation where the statistical tests are accomplished. This approach improves the sensitivity, objectivity and interpretability of results. The study compares brain images of 64 healthy controls and 59 patients with different stages of Multiple Sclerosis. Some preliminary statistical tests were performed and although the results are still under study, it shows that corticospinal tracts as the most region affected by the disease.
多发性硬化症是一种影响中枢神经系统通讯的脱髓鞘疾病。与传统的磁共振技术相比,磁共振扩散成像提供了白质中水扩散的信息,并允许早期发现异常。这项研究的目的是找出在疾病发展过程中受损的大脑区域。基于束的空间统计是一种体素的多主体统计分析,它对每个主体的图像进行非线性配准,并将其投影到一个对齐不变的束表示上,在那里完成统计检验。这种方法提高了结果的敏感性、客观性和可解释性。该研究比较了64名健康对照者和59名不同阶段多发性硬化症患者的大脑图像。进行了一些初步的统计测试,尽管结果仍在研究中,但它表明皮质脊髓束是受该疾病影响最严重的区域。
{"title":"Analysis of multiple sclerosis DTI images that uses tract based spatial statistics","authors":"J. Oliveira, M. Castelo‐Branco, Ricardo Morais, S. Baptista, João Pereira","doi":"10.1109/ENBENG.2015.7088839","DOIUrl":"https://doi.org/10.1109/ENBENG.2015.7088839","url":null,"abstract":"Multiple Sclerosis is a demyelinating disease affecting the communication in the central nervous system. Magnetic resonance diffusion imaging provides information about water diffusion in white matter and allows an early detection of abnormalities, comparing to conventional magnetic resonance techniques. The aim of this study is to find out which the brain regions that are damaged during disease progression. Tract-Based Spatial Statistics is a voxelwise multi-subject statistical analysis which performs non-linear registration of each subject's image and projects them onto an alignment-invariant tract representation where the statistical tests are accomplished. This approach improves the sensitivity, objectivity and interpretability of results. The study compares brain images of 64 healthy controls and 59 patients with different stages of Multiple Sclerosis. Some preliminary statistical tests were performed and although the results are still under study, it shows that corticospinal tracts as the most region affected by the disease.","PeriodicalId":285567,"journal":{"name":"2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG)","volume":"193 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114229143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular fingerprint of human gastric cell line infected by Helicobacter pylori 幽门螺杆菌感染人胃细胞株的分子指纹图谱
Pub Date : 2015-02-01 DOI: 10.1109/ENBENG.2015.7088877
P. Sampaio, B. Cunha, Filipa Rosa, K. Sales, M. Lopes, C. Calado
Helicobacter pylori infection represents a serious health problem, given its association with serious gastric diseases as gastric ulcers, cancer and MALT lymphoma. Currently no vaccine exists and antibiotic-based eradication therapy is already failing in more than 20% of cases. To increase the knowledge on the infection process diverse gastric cell lines, e.g. the adenocarcinona gastric (AGS) cell line, are routinely used has in vitro models of gastric epithelia. In the present work the molecular fingerprint of infected and non-infected AGS cell lines, by diverse H. pylori strains, was acquired using vibrational infrared spectroscopy. These molecular fingerprints enabled to discriminate infected from non-infected AGS cells, and infection due to different strains, by performing Principal Component Analysis. It was also possible to estimate, from the AGS cells molecular fingerprint, the effect of the infection on diverse biochemical and metabolic cellular status. In resume infra-red spectroscopy enabled the acquisition of infected AGS cells molecular fingerprint with minimal sample preparation, in a rapid, high-throughput, economic process yielding highly sensitive and informative data, most useful for promoting critical knowledge on the H. pylori infection process.
幽门螺杆菌感染是一个严重的健康问题,因为它与胃溃疡、癌症和MALT淋巴瘤等严重胃疾病有关。目前没有疫苗,基于抗生素的根除治疗在20%以上的病例中已经失败。为了增加对感染过程的了解,不同的胃细胞系,如胃腺癌(AGS)细胞系,通常用于体外胃上皮模型。本研究利用振动红外光谱技术对不同幽门螺杆菌感染的AGS细胞株和未感染的AGS细胞株进行了分子指纹图谱分析。通过主成分分析,这些分子指纹图谱能够区分感染和未感染的AGS细胞,以及不同菌株引起的感染。通过AGS细胞的分子指纹图谱,还可以估计感染对细胞多种生化代谢状态的影响。此外,红外光谱技术能够以最少的样品制备,以快速、高通量、经济的方式获得感染AGS细胞的分子指纹,产生高度敏感和信息丰富的数据,对促进幽门螺杆菌感染过程的关键知识最有用。
{"title":"Molecular fingerprint of human gastric cell line infected by Helicobacter pylori","authors":"P. Sampaio, B. Cunha, Filipa Rosa, K. Sales, M. Lopes, C. Calado","doi":"10.1109/ENBENG.2015.7088877","DOIUrl":"https://doi.org/10.1109/ENBENG.2015.7088877","url":null,"abstract":"Helicobacter pylori infection represents a serious health problem, given its association with serious gastric diseases as gastric ulcers, cancer and MALT lymphoma. Currently no vaccine exists and antibiotic-based eradication therapy is already failing in more than 20% of cases. To increase the knowledge on the infection process diverse gastric cell lines, e.g. the adenocarcinona gastric (AGS) cell line, are routinely used has in vitro models of gastric epithelia. In the present work the molecular fingerprint of infected and non-infected AGS cell lines, by diverse H. pylori strains, was acquired using vibrational infrared spectroscopy. These molecular fingerprints enabled to discriminate infected from non-infected AGS cells, and infection due to different strains, by performing Principal Component Analysis. It was also possible to estimate, from the AGS cells molecular fingerprint, the effect of the infection on diverse biochemical and metabolic cellular status. In resume infra-red spectroscopy enabled the acquisition of infected AGS cells molecular fingerprint with minimal sample preparation, in a rapid, high-throughput, economic process yielding highly sensitive and informative data, most useful for promoting critical knowledge on the H. pylori infection process.","PeriodicalId":285567,"journal":{"name":"2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG)","volume":"259 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116218163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Effect of surgical mesh implant in the uterine prolapse correction 手术补片在子宫脱垂矫正中的效果
Pub Date : 2015-02-01 DOI: 10.1109/ENBENG.2015.7088848
P. Rocha, M. Parente, T. Mascarenhas, A. Fernandes, R. Jorge
Pelvic organ prolapse (POP) is a medical condition characterized by the loss of support of the uterus, bladder or rectum, leading to its decay over the vagina. This condition affects about 75% of women from 50 years old, and about 11% of these will perform a prolapse correction surgery before being 80 years old. The most common treatment for this dysfunction is the implant of a synthetic mesh to complement the affected organ's support failure. Therefore, the effect of the mesh implant on the uterine displacement was studied through Finite Element Models (FEM). Several simulations were performed: healthy (without mesh) and dysfunctional (including the mesh and ligament damage). The ligaments' damage was simulated by modifying their mechanical properties. Comparing the results from the simulations, the mesh implant reduced the movement of the uterus to values closer to healthy ones.
盆腔器官脱垂(POP)是一种以失去子宫、膀胱或直肠的支撑为特征的医学病症,导致其在阴道上腐烂。大约75%的50岁以上的女性患有这种疾病,其中约11%的人在80岁之前会进行脱垂矫正手术。这种功能障碍最常见的治疗方法是植入合成网状物,以补充受影响器官的支持功能失效。因此,通过有限元模型研究网状植入物对子宫位移的影响。进行了几种模拟:健康(无补片)和功能失调(包括补片和韧带损伤)。通过改变韧带的力学性能来模拟韧带的损伤。对比模拟的结果,网状植入物将子宫的运动减少到更接近健康的值。
{"title":"Effect of surgical mesh implant in the uterine prolapse correction","authors":"P. Rocha, M. Parente, T. Mascarenhas, A. Fernandes, R. Jorge","doi":"10.1109/ENBENG.2015.7088848","DOIUrl":"https://doi.org/10.1109/ENBENG.2015.7088848","url":null,"abstract":"Pelvic organ prolapse (POP) is a medical condition characterized by the loss of support of the uterus, bladder or rectum, leading to its decay over the vagina. This condition affects about 75% of women from 50 years old, and about 11% of these will perform a prolapse correction surgery before being 80 years old. The most common treatment for this dysfunction is the implant of a synthetic mesh to complement the affected organ's support failure. Therefore, the effect of the mesh implant on the uterine displacement was studied through Finite Element Models (FEM). Several simulations were performed: healthy (without mesh) and dysfunctional (including the mesh and ligament damage). The ligaments' damage was simulated by modifying their mechanical properties. Comparing the results from the simulations, the mesh implant reduced the movement of the uterus to values closer to healthy ones.","PeriodicalId":285567,"journal":{"name":"2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG)","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128107880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
The numerical analysis of a restored tooth using meshless methods 用无网格法对修复牙进行数值分析
Pub Date : 2015-02-01 DOI: 10.1109/ENBENG.2015.7088872
C.S.S. Tavares, J. Belinha, L. Dinis, R. Jorge
In this work it is study how the remaining coronal dentin and type of rehabilitation influences the strain, the stress distribution, and the fracture resistance of restored teeth. Thus, an advance discretization numerical technique - a meshless method - is used to analyse the effects of the rehabilitation technical solutions on the biomechanical behaviour of restored teeth. The meshless method used in this work is the Natural Neighbour Radial Point Interpolation Method (NNRPIM). Within the NNRPIM, the Natural Neighbour concept is used in order to enforce the nodal connectivity and to construct a node-depending background mesh. The NNRPIM interpolation functions possess the delta Kronecker property, which simplify the imposition of the natural and essential boundary condition. The objective of this work is to extend and validate the NNRPIM to the elasto-static numerical analysis of restored maxillary molar. Several numerical examples are analysed and the obtained results are compared with clinical cases.
本文主要研究剩余的冠状牙本质和修复方式对修复牙的应变、应力分布和抗断裂能力的影响。因此,采用一种先进的离散化数值技术——无网格法来分析修复技术方案对修复牙齿生物力学行为的影响。本研究采用的无网格方法是自然邻点径向插值法(NNRPIM)。在NNRPIM中,使用自然邻居概念来强制节点连接并构建依赖于节点的背景网格。NNRPIM插值函数具有Kronecker性质,简化了自然边界条件和本质边界条件的设置。本研究的目的是将NNRPIM扩展并验证到修复上颌磨牙的弹性静力数值分析中。对几个数值算例进行了分析,并将所得结果与临床病例进行了比较。
{"title":"The numerical analysis of a restored tooth using meshless methods","authors":"C.S.S. Tavares, J. Belinha, L. Dinis, R. Jorge","doi":"10.1109/ENBENG.2015.7088872","DOIUrl":"https://doi.org/10.1109/ENBENG.2015.7088872","url":null,"abstract":"In this work it is study how the remaining coronal dentin and type of rehabilitation influences the strain, the stress distribution, and the fracture resistance of restored teeth. Thus, an advance discretization numerical technique - a meshless method - is used to analyse the effects of the rehabilitation technical solutions on the biomechanical behaviour of restored teeth. The meshless method used in this work is the Natural Neighbour Radial Point Interpolation Method (NNRPIM). Within the NNRPIM, the Natural Neighbour concept is used in order to enforce the nodal connectivity and to construct a node-depending background mesh. The NNRPIM interpolation functions possess the delta Kronecker property, which simplify the imposition of the natural and essential boundary condition. The objective of this work is to extend and validate the NNRPIM to the elasto-static numerical analysis of restored maxillary molar. Several numerical examples are analysed and the obtained results are compared with clinical cases.","PeriodicalId":285567,"journal":{"name":"2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG)","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114941593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Characterization of silicon photodiodes for diffuse reflectance signal extraction 用于漫反射信号提取的硅光电二极管的表征
Pub Date : 2015-02-01 DOI: 10.1109/ENBENG.2015.7088844
S. Pimenta, J. P. Carmo, R. G. Correia, G. Minas, E. M. Castanheira
Early detection of gastrointestinal (GI) cancers is one of most important concerns in medical field. Its detection at the earliest stage is crucial to increase the patient survival chances. Optical signals extraction and analysis, specifically diffuse reflectance and intrinsic fluorescence, may improve the ability to detect GI dysplasia, once some morphological and biochemical changes on the tissues (related with early cancer progression) can modify these signals' shape and intensity. The project under this paper aims to develop a chip-sized spectroscopy microsystem for the early detection of GI cancer. This paper presents the characterization of different dimensions pn-junction silicon photodiodes (n+/p-epilayer type) fabricated in a standard 0.7 μm CMOS process. An array comprising 16 of those photodiodes must be implemented for the diffuse reflectance and intrinsic fluorescence signals measurements. The main goal is to conclude about the photodiodes minimum dimensions, taking into account its capacity to extract the signals in the relevant spectral band (350 nm-750 nm), not comprising the microsystem dimensions. With this study, it can be concluded that a 100 × 100 μm2 active area presents a quantum efficiency suitable to extract diffuse reflectance signals, which was proven using a test phantom representative of a GI tissue.
早期发现胃肠道肿瘤一直是医学界关注的焦点之一。早期发现对提高患者的生存机会至关重要。光信号的提取和分析,特别是漫反射和本征荧光,可能会提高检测GI异常增生的能力,一旦组织上的一些形态学和生化变化(与癌症早期进展有关)可以改变这些信号的形状和强度。本课题旨在开发一种芯片大小的光谱微系统,用于早期检测胃肠道肿瘤。本文介绍了在标准的0.7 μm CMOS工艺中制备的不同尺寸pn结硅光电二极管(n+/p-epilayer型)的特性。为了漫反射和本征荧光信号的测量,必须实现由16个光电二极管组成的阵列。主要目标是总结光电二极管的最小尺寸,考虑其在相关光谱带(350 nm-750 nm)提取信号的能力,不包括微系统尺寸。通过本研究,可以得出结论,100 × 100 μm2的有源区域具有适合提取漫反射信号的量子效率,并通过代表胃肠道组织的测试体验证了这一结论。
{"title":"Characterization of silicon photodiodes for diffuse reflectance signal extraction","authors":"S. Pimenta, J. P. Carmo, R. G. Correia, G. Minas, E. M. Castanheira","doi":"10.1109/ENBENG.2015.7088844","DOIUrl":"https://doi.org/10.1109/ENBENG.2015.7088844","url":null,"abstract":"Early detection of gastrointestinal (GI) cancers is one of most important concerns in medical field. Its detection at the earliest stage is crucial to increase the patient survival chances. Optical signals extraction and analysis, specifically diffuse reflectance and intrinsic fluorescence, may improve the ability to detect GI dysplasia, once some morphological and biochemical changes on the tissues (related with early cancer progression) can modify these signals' shape and intensity. The project under this paper aims to develop a chip-sized spectroscopy microsystem for the early detection of GI cancer. This paper presents the characterization of different dimensions pn-junction silicon photodiodes (n+/p-epilayer type) fabricated in a standard 0.7 μm CMOS process. An array comprising 16 of those photodiodes must be implemented for the diffuse reflectance and intrinsic fluorescence signals measurements. The main goal is to conclude about the photodiodes minimum dimensions, taking into account its capacity to extract the signals in the relevant spectral band (350 nm-750 nm), not comprising the microsystem dimensions. With this study, it can be concluded that a 100 × 100 μm2 active area presents a quantum efficiency suitable to extract diffuse reflectance signals, which was proven using a test phantom representative of a GI tissue.","PeriodicalId":285567,"journal":{"name":"2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132612202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Active pedal exerciser for leg rehabilitation 用于腿部康复的主动踏板健身器
Pub Date : 2015-02-01 DOI: 10.1109/ENBENG.2015.7088802
Filipa Garcia, J. Ferreira, Paulo Ferreira, Stephane Cruz, M. Crisostomo, A. Coimbra
Summary form only given. Given the importance of the ability to drive the lower limbs to perform most daily activities for all people and knowing that there is a constant need to develop new ways to help people who do not fully make use of this ability, either by external or physical causes, a tool for motion rehabilitation is being developed. In the market there are already some products for leg rehabilitation. Pedal exercisers and static bicycles are the most common. Mostly, they are very rudimentary because its practise can't be controlled by the health staff through software. A number of them have virtual environments for simulation of outdoor exercise. Some products that aren't yet on the market have new and important features, like reacting to the patient's performance to optimize the rehabilitation process, through an adjustable resistant motor [1]. Other can stimulate patient's legs movement because of their motor, and alternate between cycling forward or backward [2]. There is also a prototype of one device that trains lower limbs bilaterally [3]. The rehabilitation device presented here is based on a kind of motor assisted bicycle, which will gradually be triggered, depending on the pressure exerted on the force sensors existing on the pedals, allowing to compensate the leg with mobility problems, helping it to perform the expected cycling movement. There is also a sensor to monitor the patient's heart rate. To obtain the pressure sensor and heart rate values a data acquisition system is used. It is connected to a computer and to the motor controller. With it, it is possible to perform motor control to ensure the efficiency of the treatment and the patient safety. There is also the capability of exercising each leg with different parameters, which represents a very useful advantage for stroke patients, and can also compensate for a missing or impaired limb by mimicking the performance of the healthy leg. A computer interface allows the physiotherapist in charge to make a responsible management and an efficient monitoring of the equipment. It is expected to test a prototype in a public hospital soon.
只提供摘要形式。考虑到驱动下肢进行大多数日常活动的能力对所有人的重要性,并且知道不断需要开发新的方法来帮助那些由于外部或物理原因而不能充分利用这种能力的人,运动康复工具正在开发中。市场上已经有一些腿部康复的产品。踏板健身器和静态自行车是最常见的。大多数情况下,它们都非常初级,因为医护人员无法通过软件控制这种做法。其中一些有模拟户外运动的虚拟环境。一些尚未上市的产品具有新的和重要的功能,比如通过可调节的抵抗运动[1]对患者的表现做出反应,以优化康复过程。另一种可以刺激患者的腿部运动,因为他们的马达,并交替在向前或向后骑b[2]。还有一种装置的原型,可以训练双侧下肢。这里展示的康复装置是基于一种电动辅助自行车,它会逐渐触发,根据施加在踏板上的力传感器上的压力,允许补偿腿部的行动问题,帮助它完成预期的骑行运动。还有一个传感器可以监测病人的心率。为了获得压力传感器和心率值,使用了数据采集系统。它与计算机和电机控制器相连。有了它,就可以进行运动控制,以确保治疗的效率和患者的安全。它还可以用不同的参数锻炼每条腿,这对中风患者来说是一个非常有用的优势,也可以通过模仿健康腿的表现来弥补缺失或受损的肢体。计算机接口允许负责的物理治疗师对设备进行负责任的管理和有效的监控。预计不久将在一家公立医院测试原型机。
{"title":"Active pedal exerciser for leg rehabilitation","authors":"Filipa Garcia, J. Ferreira, Paulo Ferreira, Stephane Cruz, M. Crisostomo, A. Coimbra","doi":"10.1109/ENBENG.2015.7088802","DOIUrl":"https://doi.org/10.1109/ENBENG.2015.7088802","url":null,"abstract":"Summary form only given. Given the importance of the ability to drive the lower limbs to perform most daily activities for all people and knowing that there is a constant need to develop new ways to help people who do not fully make use of this ability, either by external or physical causes, a tool for motion rehabilitation is being developed. In the market there are already some products for leg rehabilitation. Pedal exercisers and static bicycles are the most common. Mostly, they are very rudimentary because its practise can't be controlled by the health staff through software. A number of them have virtual environments for simulation of outdoor exercise. Some products that aren't yet on the market have new and important features, like reacting to the patient's performance to optimize the rehabilitation process, through an adjustable resistant motor [1]. Other can stimulate patient's legs movement because of their motor, and alternate between cycling forward or backward [2]. There is also a prototype of one device that trains lower limbs bilaterally [3]. The rehabilitation device presented here is based on a kind of motor assisted bicycle, which will gradually be triggered, depending on the pressure exerted on the force sensors existing on the pedals, allowing to compensate the leg with mobility problems, helping it to perform the expected cycling movement. There is also a sensor to monitor the patient's heart rate. To obtain the pressure sensor and heart rate values a data acquisition system is used. It is connected to a computer and to the motor controller. With it, it is possible to perform motor control to ensure the efficiency of the treatment and the patient safety. There is also the capability of exercising each leg with different parameters, which represents a very useful advantage for stroke patients, and can also compensate for a missing or impaired limb by mimicking the performance of the healthy leg. A computer interface allows the physiotherapist in charge to make a responsible management and an efficient monitoring of the equipment. It is expected to test a prototype in a public hospital soon.","PeriodicalId":285567,"journal":{"name":"2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132816180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Implementation of a multivibrational medical device to assist the removal of teeth and roots 一种多振动医疗装置的实施,以帮助去除牙齿和牙根
Pub Date : 2015-02-01 DOI: 10.1109/ENBENG.2015.7088841
Sara Setas, E. Seabra, L. F. Silva, H. Puga, C. Pombo, J. Mendes
The standard practice of dental extraction is performed using rigid instruments in a process involving high mechanical strength and a post-operative painful for patients. This work presents the stages of design and development of an instrument capable of acting in the most critical phase of the process, with induction of vibration at high frequencies, and it is expected to decrease the required the extraction force to perform as well as damages caused by the present procedure.
拔牙的标准做法是使用刚性器械,在一个过程中涉及高机械强度和术后疼痛的病人。这项工作介绍了一种仪器的设计和开发阶段,该仪器能够在过程的最关键阶段发挥作用,具有高频振动感应,并且有望减少执行所需的提取力以及当前程序造成的损害。
{"title":"Implementation of a multivibrational medical device to assist the removal of teeth and roots","authors":"Sara Setas, E. Seabra, L. F. Silva, H. Puga, C. Pombo, J. Mendes","doi":"10.1109/ENBENG.2015.7088841","DOIUrl":"https://doi.org/10.1109/ENBENG.2015.7088841","url":null,"abstract":"The standard practice of dental extraction is performed using rigid instruments in a process involving high mechanical strength and a post-operative painful for patients. This work presents the stages of design and development of an instrument capable of acting in the most critical phase of the process, with induction of vibration at high frequencies, and it is expected to decrease the required the extraction force to perform as well as damages caused by the present procedure.","PeriodicalId":285567,"journal":{"name":"2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG)","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124077645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG)
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1