R. Al-Wassia, Nisreen Awad, Rahaf A. Al Odaini, S. Alkhayyat, Atlal M. Abusanad, Hani Almarzouki, M. Attar, Talal A. Al Khatib, C. Constantinescu
The purpose of this study is to assess the loco-regional control and overall survival in head and neck cancer patients, as well as evaluate the clinical benefit of intensity-modulated radiotherapy implemented in 2011 at our Hospital. Data of 117 patients between 2007 and 2014 was reviewed retrospectively. Cumulative survival and disease control rates were calculated by Kaplan-Meier product-limit actuarial method. Loco-regional control and survival rates for intensity modulated and three-dimensional conformal radiotherapy were compared by a logistic regression test. After a median follow-up of 12 months, 53 (51%) patients who underwent radical radiotherapy were free of disease, 43 (42%) with disease, and seven (7%) unknown. During this time, 31 (26%) patients died from the disease. Using actuarial estimates for the two-year follow-up, this study found that significant gains in survival were obtained by switching treatment modalities. The benchmarking gives reassurance that our results are comparable to the best clinical practices internationally.
{"title":"Head and Neck Cancer a Single Institution Experience: King Abdulaziz University","authors":"R. Al-Wassia, Nisreen Awad, Rahaf A. Al Odaini, S. Alkhayyat, Atlal M. Abusanad, Hani Almarzouki, M. Attar, Talal A. Al Khatib, C. Constantinescu","doi":"10.4197/med.22-3.2","DOIUrl":"https://doi.org/10.4197/med.22-3.2","url":null,"abstract":"The purpose of this study is to assess the loco-regional control and overall survival in head and neck cancer patients, as well as evaluate the clinical benefit of intensity-modulated radiotherapy implemented in 2011 at our Hospital. Data of 117 patients between 2007 and 2014 was reviewed retrospectively. Cumulative survival and disease control rates were calculated by Kaplan-Meier product-limit actuarial method. Loco-regional control and survival rates for intensity modulated and three-dimensional conformal radiotherapy were compared by a logistic regression test. After a median follow-up of 12 months, 53 (51%) patients who underwent radical radiotherapy were free of disease, 43 (42%) with disease, and seven (7%) unknown. During this time, 31 (26%) patients died from the disease. Using actuarial estimates for the two-year follow-up, this study found that significant gains in survival were obtained by switching treatment modalities. The benchmarking gives reassurance that our results are comparable to the best clinical practices internationally.","PeriodicalId":287732,"journal":{"name":"Journal of King Abdulaziz University-medical Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129718516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rhabdomyosarcoma is a rare malignancy that develops primarily in young individuals. We report a 19-year-old female with rhabdomyosarcoma who was classified with stage IIA disease, based on the clinical grouping system developed by the Intergroup Rhabdomyosarcoma Study Group in 1972. The patient was treated with surgery and chemotherapy. The histopathological and radiological assessment showed no residual tumor in adjacent tissues to contradict the clinical classification. The patient was scheduled for radiotherapy but left against medical advice and returned pregnant six months later with recurrence. She chose not to terminate the pregnancy, restricting the treatment options to chemotherapy. At 32 weeks of gestation, she underwent a caesarean section due to fetal distress. The patient deteriorated and passed away shortly after. The baby, however, is healthy. Although recent modalities of combined surgery, chemotherapy, and radiotherapy have improved the survival of such malignancies, they still have poor outcomes when during a pregnancy.
{"title":"Maternal and Fetal Outcome in a Patient with Buccal Embryonal Rhabdomyosarcoma","authors":"W. Fageeh, Ossama H. Raffa","doi":"10.4197/MED.22-3.7","DOIUrl":"https://doi.org/10.4197/MED.22-3.7","url":null,"abstract":"Rhabdomyosarcoma is a rare malignancy that develops primarily in young individuals. We report a 19-year-old female with rhabdomyosarcoma who was classified with stage IIA disease, based on the clinical grouping system developed by the Intergroup Rhabdomyosarcoma Study Group in 1972. The patient was treated with surgery and chemotherapy. The histopathological and radiological assessment showed no residual tumor in adjacent tissues to contradict the clinical classification. The patient was scheduled for radiotherapy but left against medical advice and returned pregnant six months later with recurrence. She chose not to terminate the pregnancy, restricting the treatment options to chemotherapy. At 32 weeks of gestation, she underwent a caesarean section due to fetal distress. The patient deteriorated and passed away shortly after. The baby, however, is healthy. Although recent modalities of combined surgery, chemotherapy, and radiotherapy have improved the survival of such malignancies, they still have poor outcomes when during a pregnancy.","PeriodicalId":287732,"journal":{"name":"Journal of King Abdulaziz University-medical Sciences","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127676446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdulrahman S. Alboog, T. Tayeb, Mohammed O. Alsager, Salwa A. Alnajjar, G. Damanhouri, J. Jarullah, S. Hindawi
The treatment of patients with sickle cell disease frequently requires transfusion of red blood cells. Complications due to alloimmunization of red blood cells antigen remain a major risk as a post transfusion effect. The objective of this study is to determine the frequency of red cell alloimmunization in Jeddah, Saudi Arabia. A retrospective cross-section study of sickle cell disease patients at King Abdulaziz University Hospital between 2012 and 2013 was performed. Demographic characteristics and transfusion history was recorded. Blood samples were analyzed for alloimmunization using immunohematological technique. A total of 234 sickle cell patients were analyzed, of which 30 (12.8%) showed alloantibodies. A total of 43 alloantibodies were found out of which 28 belonged to Rh group, eight belonged to Kell while three belonged to MNS group. Demographic and transfusion characteristics were analyzed between alloimmunized and nonalloimmunized sickle cell disease patients. The rate of alloimmunization in Jeddah, Saudi Arabia was 12.8%. There was significant difference observed between alloantibodies detection between transfused patients compared to non-transfused patients. The consequences of red blood cell alloimmunization are highly significant and therefore immune hematological testing is highly recommended.
{"title":"Red Blood Cell Alloimmunization in Sickle Cell Disease Patients in Jeddah, Saudi Arabia: A Pilot Study.","authors":"Abdulrahman S. Alboog, T. Tayeb, Mohammed O. Alsager, Salwa A. Alnajjar, G. Damanhouri, J. Jarullah, S. Hindawi","doi":"10.4197/MED.22-3.5","DOIUrl":"https://doi.org/10.4197/MED.22-3.5","url":null,"abstract":"The treatment of patients with sickle cell disease frequently requires transfusion of red blood cells. Complications due to alloimmunization of red blood cells antigen remain a major risk as a post transfusion effect. The objective of this study is to determine the frequency of red cell alloimmunization in Jeddah, Saudi Arabia. A retrospective cross-section study of sickle cell disease patients at King Abdulaziz University Hospital between 2012 and 2013 was performed. Demographic characteristics and transfusion history was recorded. Blood samples were analyzed for alloimmunization using immunohematological technique. A total of 234 sickle cell patients were analyzed, of which 30 (12.8%) showed alloantibodies. A total of 43 alloantibodies were found out of which 28 belonged to Rh group, eight belonged to Kell while three belonged to MNS group. Demographic and transfusion characteristics were analyzed between alloimmunized and nonalloimmunized sickle cell disease patients. The rate of alloimmunization in Jeddah, Saudi Arabia was 12.8%. There was significant difference observed between alloantibodies detection between transfused patients compared to non-transfused patients. The consequences of red blood cell alloimmunization are highly significant and therefore immune hematological testing is highly recommended.","PeriodicalId":287732,"journal":{"name":"Journal of King Abdulaziz University-medical Sciences","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126716355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Citation Mahran SA, Elias AY, Janbi FS, El-Deek BS. Relationship between clinical and radiographic fi ndings in osteoarthritis knee: a cross-sectional study. JKAU Med Sci 2015; 22 (2): 1-9. DOI: 10.4197/Med. 22.2.1 Abstract Several studies have suggested that there is a high discrepancy between clinical and radiographic knee osteoarthritis. The objectives of this study were to examine association between radiographic classifi cation and clinical manifestations of knee osteoarthritis, and to determine if the assessment of individual radiographic features was superior to the general radiographic scale in establishing such a relationship. A total of 125 patients with knee osteoarthritis were enrolled in this study. Radiographic features were assessed with the Kellgren-Lawrence grade scale for general radiographic grading, and a line-drawing atlas for detailed radiographic analysis. The severity of knee pain, stiff ness, and disability were measured using the Western Ontario and McMaster Universities Osteoarthritis Index. Patients' age and pain duration were found to correlate signifi cantly with knee pain, stiff ness, and disability. No association between general radiographic grading scale and clinical manifestations was found. However in detailed radiographic analysis, osteophyte site at the patellofemoral joint was found to correlate with knee stiff ness. In conclusion, radiographic scores were not found to be closely associated with the clinical features of knee osteoarthritis. The results of knee X-rays should not be used in isolation when a management decision is to be taken for patients with knee osteoarthritis.
引用本文Mahran SA, Elias AY, Janbi FS, El-Deek BS。膝关节骨关节炎临床与影像学表现的关系:一项横断面研究。中华医学会医学杂志2015;22(2): 1-9。DOI: 10.4197 /地中海。22.2.1摘要多项研究表明，膝关节骨关节炎的临床表现与影像学表现存在很大差异。本研究的目的是探讨膝关节骨关节炎的x线片分类与临床表现之间的关系，并确定在建立这种关系方面，个体x线片特征的评估是否优于一般x线片评分。本研究共纳入125例膝骨关节炎患者。影像学特征评估采用Kellgren-Lawrence分级法进行一般影像学分级，并使用线描图集进行详细的影像学分析。使用西安大略和麦克马斯特大学骨关节炎指数测量膝关节疼痛、僵硬和残疾的严重程度。发现患者的年龄和疼痛持续时间与膝关节疼痛、僵硬和残疾显著相关。一般放射学分级量表与临床表现无相关性。然而，在详细的x线分析中，发现髌股关节处的骨赘与膝关节僵硬有关。总之，我们没有发现影像学评分与膝骨关节炎的临床特征密切相关。当对膝骨关节炎患者进行治疗决策时，不应单独使用膝关节x光片的结果。
{"title":"Relationship Between Clinical and Radiographic Findings in Osteoarthritis Knee: A Cross-Sectional Study","authors":"S. Mahran, A. Y. Elias, Fadwa S. Janbi, B. Eldeek","doi":"10.4197/med.22-2.1","DOIUrl":"https://doi.org/10.4197/med.22-2.1","url":null,"abstract":"Citation Mahran SA, Elias AY, Janbi FS, El-Deek BS. Relationship between clinical and radiographic fi ndings in osteoarthritis knee: a cross-sectional study. JKAU Med Sci 2015; 22 (2): 1-9. DOI: 10.4197/Med. 22.2.1 Abstract Several studies have suggested that there is a high discrepancy between clinical and radiographic knee osteoarthritis. The objectives of this study were to examine association between radiographic classifi cation and clinical manifestations of knee osteoarthritis, and to determine if the assessment of individual radiographic features was superior to the general radiographic scale in establishing such a relationship. A total of 125 patients with knee osteoarthritis were enrolled in this study. Radiographic features were assessed with the Kellgren-Lawrence grade scale for general radiographic grading, and a line-drawing atlas for detailed radiographic analysis. The severity of knee pain, stiff ness, and disability were measured using the Western Ontario and McMaster Universities Osteoarthritis Index. Patients' age and pain duration were found to correlate signifi cantly with knee pain, stiff ness, and disability. No association between general radiographic grading scale and clinical manifestations was found. However in detailed radiographic analysis, osteophyte site at the patellofemoral joint was found to correlate with knee stiff ness. In conclusion, radiographic scores were not found to be closely associated with the clinical features of knee osteoarthritis. The results of knee X-rays should not be used in isolation when a management decision is to be taken for patients with knee osteoarthritis.","PeriodicalId":287732,"journal":{"name":"Journal of King Abdulaziz University-medical Sciences","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121088825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Citation Al Sayyad AJ. Robotic surgery for large renal stones: prospective three years singleinstitution experience. JKAU Med Sci 2015; 22 (2): 31-37. DOI: 10.4197/Med. 22.2.5 Abstract This prospective study evaluates the role of robotic surgery in the management of large renal stones. Robotic renal stone surgery is safe and eff ective, and may be considered among the treatment options for large renal calculi in adults, especially for patients with concomitant ureteropelvic junction obstruction. The benefi ts brought by robotic systems include improved 3-D visualization, greater dexterity, precision, and increased range of motion. Thus, robotic pyelolithotomy has been recommended for the treatment of renal calculi with concurrent upper tract abnormalities. The effi cacy and safety of robotic pyelolithotomy as a treatment of large renal pelvic stones and partial staghorn stones is evident in our study, with a substantially high stone clearance rate. We were able to complete the robotic procedures safely and successfully in all but one of our 38 patients, who was converted to open surgery due to bleeding and severe adhesions. Overall, we found this procedure feasible, safe, effi cacious, and high yielding in the management of large renal stones, especially when the procedure is accompanied by renal pelvis reconstructive surgery.
{"title":"Robotic Surgery for Large Renal Stones: Prospective Three Years Single-Institution Experience","authors":"Ahmed J. Al Sayyad","doi":"10.4197/med.22-2.5","DOIUrl":"https://doi.org/10.4197/med.22-2.5","url":null,"abstract":"Citation Al Sayyad AJ. Robotic surgery for large renal stones: prospective three years singleinstitution experience. JKAU Med Sci 2015; 22 (2): 31-37. DOI: 10.4197/Med. 22.2.5 Abstract This prospective study evaluates the role of robotic surgery in the management of large renal stones. Robotic renal stone surgery is safe and eff ective, and may be considered among the treatment options for large renal calculi in adults, especially for patients with concomitant ureteropelvic junction obstruction. The benefi ts brought by robotic systems include improved 3-D visualization, greater dexterity, precision, and increased range of motion. Thus, robotic pyelolithotomy has been recommended for the treatment of renal calculi with concurrent upper tract abnormalities. The effi cacy and safety of robotic pyelolithotomy as a treatment of large renal pelvic stones and partial staghorn stones is evident in our study, with a substantially high stone clearance rate. We were able to complete the robotic procedures safely and successfully in all but one of our 38 patients, who was converted to open surgery due to bleeding and severe adhesions. Overall, we found this procedure feasible, safe, effi cacious, and high yielding in the management of large renal stones, especially when the procedure is accompanied by renal pelvis reconstructive surgery.","PeriodicalId":287732,"journal":{"name":"Journal of King Abdulaziz University-medical Sciences","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131258404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A retrospective study was conducted to evaluate the characteristics of atrial fibrillation in a cohort of Saudi women, and its impact on morbidity. A complete medical history was obtained and all participants underwent a complete review of clinical data including electrocardiogram, echocardiogram, blood pressure measurement, and thyroid examination. The following laboratory examinations were performed: international normalized ratio; thyroid stimulating hormone; triiodothyronine; thyroxine; total cholesterol; triglyceride; low-density and high-density lipoprotein. A history of hospitalizations, stroke and in-hospital mortality were recorded. We recruited 84 women; the mean age was 61.8 years and the mean body mass index was 28.45 kg/m2. The mean hemoglobin level of the patients was 12.2 g/dL and the mean thyroid stimulating hormone level was 3.75 mIU/L. The target international normalized ratio was achieved in 58% of treated patients; 70% of the under target International Normalized Ration patients had been hospitalized more than once and 19% had suffered a stroke. Overall, international normalized ratio demonstrates gaps in the management of women with atrial fibrillation, and the negative impact on patient outcome, indicating the need to tailor treatment plans to the goals and requirements of these patients.
{"title":"Clinical Characteristics of Atrial Fibrillation in Saudi Women Cohort and Its Clinical Impact in a Tertiary University Hospital","authors":"K. Alghalayini","doi":"10.4197/MED.22-2.2","DOIUrl":"https://doi.org/10.4197/MED.22-2.2","url":null,"abstract":"A retrospective study was conducted to evaluate the characteristics of atrial fibrillation in a cohort of Saudi women, and its impact on morbidity. A complete medical history was obtained and all participants underwent a complete review of clinical data including electrocardiogram, echocardiogram, blood pressure measurement, and thyroid examination. The following laboratory examinations were performed: international normalized ratio; thyroid stimulating hormone; triiodothyronine; thyroxine; total cholesterol; triglyceride; low-density and high-density lipoprotein. A history of hospitalizations, stroke and in-hospital mortality were recorded. We recruited 84 women; the mean age was 61.8 years and the mean body mass index was 28.45 kg/m2. The mean hemoglobin level of the patients was 12.2 g/dL and the mean thyroid stimulating hormone level was 3.75 mIU/L. The target international normalized ratio was achieved in 58% of treated patients; 70% of the under target International Normalized Ration patients had been hospitalized more than once and 19% had suffered a stroke. Overall, international normalized ratio demonstrates gaps in the management of women with atrial fibrillation, and the negative impact on patient outcome, indicating the need to tailor treatment plans to the goals and requirements of these patients.","PeriodicalId":287732,"journal":{"name":"Journal of King Abdulaziz University-medical Sciences","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125422534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Citation Suliman SM. The use of omega-3 fatty acids as an alternative treatment for attention defi cit hyperactivity disorder in children. JKAU Med Sci 2015; 22 (2): 47-52. DOI: 10.4197/Med. 22.2.7 Abstract This case report studies the effi cacy of omega-3 fatty acids as an alternative to using psychopharmacological agents for treating patients with Attention-Defi cit Hyperactivity Disorder. While this study may not end the controversy concerning the eff ectiveness of omega-3, it does establish a very solid case for using omega-3 fatty acids as an augmenting agent along with a lower than recommended minimum starting stimulant dose.
{"title":"The Use of Omega-3 Fatty Acids as an Alternative Treatment for Attention Deficit Hyperactivity Disorder in Children","authors":"S. M. Suliman","doi":"10.4197/med.22-2.7","DOIUrl":"https://doi.org/10.4197/med.22-2.7","url":null,"abstract":"Citation Suliman SM. The use of omega-3 fatty acids as an alternative treatment for attention defi cit hyperactivity disorder in children. JKAU Med Sci 2015; 22 (2): 47-52. DOI: 10.4197/Med. 22.2.7 Abstract This case report studies the effi cacy of omega-3 fatty acids as an alternative to using psychopharmacological agents for treating patients with Attention-Defi cit Hyperactivity Disorder. While this study may not end the controversy concerning the eff ectiveness of omega-3, it does establish a very solid case for using omega-3 fatty acids as an augmenting agent along with a lower than recommended minimum starting stimulant dose.","PeriodicalId":287732,"journal":{"name":"Journal of King Abdulaziz University-medical Sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127604963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Citation Abduljabbar AH. Characteristic brain imaging fi ndings in a patient with joubert syndrome and segmental glomerulosclerosis. JKAU Med Sci 2015; 22 (2): 53-57. DOI: 10.4197/Med. 22.2.8 Abstract Joubert syndrome is a rare disorder inherited as an autosomal recessive trait. It has distinctive clinical features and specifi c brain imaging fi ndings on magnetic resonance imaging. Patients present clinically with hyperpnea, apnea, ocular abnormalities, developmental delay and truncal ataxia. In this case report, we illustrate a patient with Joubert syndrome and chronic renal failure. Magmetic resonance imaging examination revealed the characteristic "molar tooth" appearance of the brain stem, "bat-wing" shaped 4th ventricle, cleft vermis and deep interpeduncular fossa consistent with the diagnosis.
{"title":"Characteristic Brain Imaging Findings in a Patient with Joubert Syndrome and Segmental Glomerulosclerosis","authors":"A. Abduljabbar","doi":"10.4197/med.22-2.8","DOIUrl":"https://doi.org/10.4197/med.22-2.8","url":null,"abstract":"Citation Abduljabbar AH. Characteristic brain imaging fi ndings in a patient with joubert syndrome and segmental glomerulosclerosis. JKAU Med Sci 2015; 22 (2): 53-57. DOI: 10.4197/Med. 22.2.8 Abstract Joubert syndrome is a rare disorder inherited as an autosomal recessive trait. It has distinctive clinical features and specifi c brain imaging fi ndings on magnetic resonance imaging. Patients present clinically with hyperpnea, apnea, ocular abnormalities, developmental delay and truncal ataxia. In this case report, we illustrate a patient with Joubert syndrome and chronic renal failure. Magmetic resonance imaging examination revealed the characteristic \"molar tooth\" appearance of the brain stem, \"bat-wing\" shaped 4th ventricle, cleft vermis and deep interpeduncular fossa consistent with the diagnosis.","PeriodicalId":287732,"journal":{"name":"Journal of King Abdulaziz University-medical Sciences","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123476829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Because left main coronary artery disease carries a high risk of morbidity and mortality, this retrospective study will review the data and results of surgical management of left main coronary artery disease, in King Abdulaziz University Hospital. 448 patients underwent coronary bypass graft into two groups, left main group (50) patients and non-left main group (398) patients. Preoperative data, risk factors and cardiac catheterization findings were compared in between the two groups in addition to perioperative morbidity and mortality. Patients in the left main group were younger in age with significantly lower ejection fraction and more risk factors (hypertension, dyslipidemia, and smoking). In our study the left main group patients had higher mortality than non-left main patients [4 patients = 8%, 6 patients = 1.8%]; the most common cause of perioperative mortality in the left main group was low cardiac output state, and the most common complications were perioperative myocardial infarction and prolonged ventilation. The higher mortality and morbidity associated with surgery for left main coronary artery disease can be explained by the higher risk profi le, the need of urgent surgery and critical preoperative status.
{"title":"Coronary Artery Bypass Graft for Left Main Coronary Artery Disease","authors":"H. Jabbad","doi":"10.4197/med.22-2.34","DOIUrl":"https://doi.org/10.4197/med.22-2.34","url":null,"abstract":"Because left main coronary artery disease carries a high risk of morbidity and mortality, this retrospective study will review the data and results of surgical management of left main coronary artery disease, in King Abdulaziz University Hospital. 448 patients underwent coronary bypass graft into two groups, left main group (50) patients and non-left main group (398) patients. Preoperative data, risk factors and cardiac catheterization findings were compared in between the two groups in addition to perioperative morbidity and mortality. Patients in the left main group were younger in age with significantly lower ejection fraction and more risk factors (hypertension, dyslipidemia, and smoking). In our study the left main group patients had higher mortality than non-left main patients [4 patients = 8%, 6 patients = 1.8%]; the most common cause of perioperative mortality in the left main group was low cardiac output state, and the most common complications were perioperative myocardial infarction and prolonged ventilation. The higher mortality and morbidity associated with surgery for left main coronary artery disease can be explained by the higher risk profi le, the need of urgent surgery and critical preoperative status.","PeriodicalId":287732,"journal":{"name":"Journal of King Abdulaziz University-medical Sciences","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127178686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Citation Aljahdali EA. The role of laparoscopy in management of congenital anomalies of the Müllerian system: Literature review and case series. JKAU Med Sci 2015; 22 (2): 39-46. DOI: 10.4197/Med. 22.2.6 Abstract Structural defects of the female reproductive tract become apparent at varying chronologic times during intrauterine life. The diagnosis of all female reproductive tract abnormalities has benefi ted from enhancements in imaging techniques and the surgical treatment thereof has improved due to advances in the techniques and instrumentation of both surgical and non-surgical procedures. In the last decade, laparoscopy has become increasingly popular and has successfully replaced several open surgical procedures. It has been applied to many aspects of gynecological surgery and has become the procedure of choice for gynecological surgery. A review of the recent literature continues to support the utilization of laparoscopy for the management of genital tract malformation. This review aims to appraise the recent literature to determine how laparoscopy may aid in the diagnosis of reproductive tract anomalies and their treatment, its success in replacing the open surgery in some cases, and the presentation of some cases that were successfully diagnosed and treated with laparoscopy.
{"title":"The Role of Laparoscopy in Management of Congenital Anomalies of the Müllerian System: Literature Review and Case Series","authors":"Ettedal A. Aljahdali","doi":"10.4197/med.22-2.6","DOIUrl":"https://doi.org/10.4197/med.22-2.6","url":null,"abstract":"Citation Aljahdali EA. The role of laparoscopy in management of congenital anomalies of the Müllerian system: Literature review and case series. JKAU Med Sci 2015; 22 (2): 39-46. DOI: 10.4197/Med. 22.2.6 Abstract Structural defects of the female reproductive tract become apparent at varying chronologic times during intrauterine life. The diagnosis of all female reproductive tract abnormalities has benefi ted from enhancements in imaging techniques and the surgical treatment thereof has improved due to advances in the techniques and instrumentation of both surgical and non-surgical procedures. In the last decade, laparoscopy has become increasingly popular and has successfully replaced several open surgical procedures. It has been applied to many aspects of gynecological surgery and has become the procedure of choice for gynecological surgery. A review of the recent literature continues to support the utilization of laparoscopy for the management of genital tract malformation. This review aims to appraise the recent literature to determine how laparoscopy may aid in the diagnosis of reproductive tract anomalies and their treatment, its success in replacing the open surgery in some cases, and the presentation of some cases that were successfully diagnosed and treated with laparoscopy.","PeriodicalId":287732,"journal":{"name":"Journal of King Abdulaziz University-medical Sciences","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129631201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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