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The Use of Proton Pump Inhibitors and Prescription Pattern by Practicing Physicians at an Academic Hospital 某学术医院执业医师质子泵抑制剂的使用及处方模式
Pub Date : 2017-12-31 DOI: 10.4197/med.24-4.2
M. Basheikh
The introduction of proton pump inhibitors has revolutionized the management of acid-related gastrointestinal disorders. Physicians use different regimen when prescribing proton pump inhibitors. In this study we aim to determine the prevalence and pattern of proton pump inhibitors prescription among practicing physicians at King Abdulaziz University Hospital in Jeddah, Saudi Arabia. A cross-sectional study was performed at different levels of doctors ranging from consultants to house officers from March-May 2014. The study included 85 doctors. The prevalence of proton pump inhibitors prescription was 57.65%. Most of the respondents are internal medicine physicians with 58.62% (29 physicians) of them prescribing proton pump inhibitors. As well, half of the surgeons (24) were prescribing proton pump inhibitors. 54.17% of house officers who participated were prescribing proton pump inhibitors. Omeprazole at a dose of 20 mg is the most commonly prescribed by 49.41%, followed by the dose 40 mg prescribed by 41.18%. The rate of prescription for proton pump inhibitors at King Abdulaziz University Hospital with different specialties and levels is comparable to the practice worldwide. It’s noted that house officers are prescribing proton pump inhibitors; they will need to be educated about the use, dosage, and side effects of proton pump inhibitors.
质子泵抑制剂的引入彻底改变了酸相关胃肠道疾病的管理。医生在处方质子泵抑制剂时使用不同的方案。在这项研究中,我们的目的是确定质子泵抑制剂处方在吉达,沙特阿拉伯阿卜杜勒阿齐兹国王大学医院执业医生的患病率和模式。在2014年3月至5月期间,对从顾问到住院医生等不同级别的医生进行了横断面研究。这项研究包括85名医生。质子泵抑制剂处方使用率为57.65%。调查对象以内科医生为主,其中58.62%(29名)的医生开质子泵抑制剂处方。同时,一半的外科医生(24人)开质子泵抑制剂的处方。54.17%的住院医生开质子泵抑制剂。奥美拉唑以20毫克的剂量最常见,占49.41%,其次是40毫克,占41.18%。阿卜杜勒阿齐兹国王大学医院不同专科和级别的质子泵抑制剂处方率与世界各地的做法相当。值得注意的是,内务人员开了质子泵抑制剂;他们需要了解质子泵抑制剂的用法、剂量和副作用。
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引用次数: 3
Staphylococcus aureus Masking Tuberculous Joint Infection 掩盖结核性关节感染的金黄色葡萄球菌
Pub Date : 2017-12-31 DOI: 10.4197/med.24-4.6
Mohammed Shaikhomer
Citation Shaikhomer M. Staphylococcus aureus masking tuberculous joint infection. JKAU Med Sci 2017; 24 (4): 41-45. DOI: 10.4197/Med. 24.4.6 Abstract Skeletal tuberculosis accounts for around 10 percent of cases of extrapulmonary tuberculosis. Hip and knee involvement are the most commonly aff ected sites after spine. Clinical manifestations include swelling, pain, and loss of joint function that progress over weeks to months. In the setting of tuberculous arthritis, local soft tissue swelling, osteopenia, and bone destruction (with relative preservation of cartilage space) occur early in the disease. Subsequent fi ndings include structural collapse, sclerotic changes, and soft tissue calcifi cation. Delay in diagnosing tuberculous arthritis can lead to functional disability and poor outcome. Superimposed infection with another organism occurs very rarely and can lead to delay in diagnosing the condition. We present a case of tuberculous knee arthritis that was superimposed with Staphylococcus aureus infection. The low index of suspicion at the initial presentation together with the superimposed infection led to a delayed diagnosis. Our patient’s risk factor was immigration from a country endemic with tuberculosis. The case was diagnosed 32 months from initial presentation. In the presence of clinical and epidemiological risk for tuberculous arthritis, requesting the appropriate tests is crucial to avoid any diagnostic delay.
引用本文Shaikhomer M.金黄色葡萄球菌掩盖结核性关节感染。中华医学会医学杂志2017;24(4): 41-45。DOI: 10.4197 /地中海。24.4.6摘要骨结核约占肺外结核病例的10%。髋关节和膝关节是继脊柱之后最常见的受累部位。临床表现包括肿胀、疼痛和关节功能丧失,持续数周至数月。在结核性关节炎的情况下,局部软组织肿胀、骨质减少和骨破坏(软骨空间相对保留)在疾病早期发生。随后的发现包括结构塌陷、硬化改变和软组织钙化。诊断结核性关节炎的延误可导致功能残疾和不良预后。与另一种生物体的重叠感染很少发生,并可能导致诊断延误。我们报告一例结核性膝关节炎合并金黄色葡萄球菌感染。最初表现时的低怀疑指数加上叠加感染导致诊断延迟。本例患者的危险因素是来自结核病流行国家的移民。该病例是在初次发病32个月后确诊的。在临床和流行病学风险结核性关节炎的存在,要求适当的测试是至关重要的,以避免任何诊断延误。
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引用次数: 0
Improved Wait Times from Abnormal Diagnostic Imaging to Biopsy of Suspicious Breast Lesions at King Abdulaziz University Hospital 阿卜杜勒阿齐兹国王大学医院从异常诊断影像到可疑乳腺病变活检的等待时间改善
Pub Date : 2017-12-31 DOI: 10.4197/med.24-4.3
L. Ashkar
Citation Ashkar LK. Improved wait times from abnormal diagnostic imaging to biopsy of suspicious breast lesions at King Abdulaziz University Hospital. JKAU Med Sci 2017; 24 (4): 15-20. DOI: 10.4197/Med. 24.4.3 Abstract Timely coordinated breast biopsies following abnormal diagnostic breast imaging reduces patient anxiety and may optimize breast cancer prognosis. Two diff erent pathways have been used in the breast unit at the Radiology Department of King Abdulaziz University Hospital. Before September 2009, all patients who had abnormal breast imaging were sent back to their referring physician, who would then request the necessary biopsy. In September 2009, we proposed the shortened pathway; and coordinated the necessary biopsy directly at our unit, instead of sending the patients back to their physician. This has saved them many weeks of agony and confusion navigating through the medical system to arrange appointments for surgical consultation and radiological biopsy. This study aimed to assess the wait time from abnormal breast imaging to the time of the biopsy. A retrospective study included an analysis of 51 consecutive breast biopsies performed before 2009, compared to 51 biopsy patients after implementing the improved pathway in 2009. It concluded that the expedited pathway reduced the wait time from 42 to 14 days until fi nal diagnosis. To ensure that targets for timeliness are realized, this improved and effi cient pathway of care was adapted permanently and has been ongoing since then.
引文Ashkar LK.缩短了阿卜杜勒阿齐兹国王大学医院从异常诊断成像到可疑乳腺病变活检的等待时间。中华医学会医学杂志2017;24(4): 15-20。DOI: 10.4197 /地中海。24.4.3摘要乳腺影像学异常诊断后及时协调乳腺活检可减少患者焦虑,优化乳腺癌预后。阿卜杜勒阿齐兹国王大学医院放射科的乳房科采用了两种不同的途径。在2009年9月之前,所有乳房成像异常的患者都被送回他们的转诊医生那里,然后他们会要求进行必要的活检。2009年9月,我们提出了缩短路径;并直接在我们的单位进行必要的活组织检查,而不是让病人回到他们的医生那里。这为他们节省了数周在医疗系统中安排手术会诊和放射活检预约的痛苦和困惑。本研究旨在评估从异常乳房成像到活检的等待时间。一项回顾性研究分析了2009年之前进行的51例连续乳腺活检,与2009年实施改进途径后的51例活检患者进行了比较。它的结论是,加速途径将等待时间从42天减少到14天,直到最终诊断。为了确保实现及时性的目标,这一经过改进和有效的护理途径得到了永久调整,并自那时以来一直在进行。
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引用次数: 0
Non-Syndromic Orofacial Cleft Malformations in Jeddah, Saudi Arabia 吉达,沙特阿拉伯的非综合征性口面裂畸形
Pub Date : 2017-09-30 DOI: 10.4197/med.24-3.1
Sabah S. Moshref, Y. Jamal, M. Fakiha, B. Awan, Fayza Alsiny, Fatma S. Alzhrani, H. Ammar, Abdullah Bamashmos, A. Baamer
This retrospective, hospital based study aims to investigate demographic and clinical characteristics of pediatric patients with orofacial cleft in Jeddah, Saudi Arabia from 2005 to 2015. Hospital surgical records from three main sources, King Abdulaziz University Hospital, Bagedo and Dr. Erfan Hospital and Dr. Soliman Fakeeh Hospital were used to identify all consecutive surgical cases with orofacial cleft referred to these hospitals. Information about age, sex, cleft types, site, maternal risk factors, associated pediatrics problems and treatment were recorded. The most common type was cleft lip and palate (40.15%), then isolated cleft palate (35.61%) and isolated cleft lip (24.24%). Maternal risk factor was mostly smoking (4.55%); pediatrics complication was mostly speech abnormalities and dental problems (75.00%); post-operative complication was mostly speech abnormalities (72.54%). Our study reveals that epidemiologic aspects of orofacial cleft in Jeddah are very similar to other Caucasian populations with a predominance of cleft lip, unilateral left side. Routine screening such as chest x-ray and ruling out hearing and speech problems as well as genetic counseling and karyotyping may be necessary in these patients. Better understanding of demographic and clinical characteristics may help guide clinical care as well as contribute to an improved understanding of pathogenesis.
本回顾性、以医院为基础的研究旨在调查2005年至2015年沙特阿拉伯吉达儿童口面部唇裂患者的人口统计学和临床特征。利用三个主要来源的医院手术记录,即阿卜杜勒阿齐兹国王大学医院、Bagedo和Erfan医生医院以及Soliman Fakeeh医生医院,来确定转诊到这些医院的所有连续的唇腭裂手术病例。记录有关年龄、性别、唇裂类型、部位、产妇危险因素、相关儿科问题和治疗的信息。最常见的是唇腭裂(40.15%),其次是孤立性腭裂(35.61%)和孤立性唇裂(24.24%)。产妇危险因素以吸烟为主(4.55%);儿科并发症以语言异常和牙齿问题为主(75.00%);术后并发症以言语异常多见(72.54%)。我们的研究表明,吉达的口面裂的流行病学方面与其他高加索人群非常相似,以单侧左侧唇裂为主。常规筛查,如胸部x光检查,排除听力和语言问题,以及遗传咨询和核型分析可能是必要的。更好地了解人口统计学和临床特征有助于指导临床护理,并有助于提高对发病机制的理解。
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引用次数: 2
The Association Between Physical Activity and Obesity among School Children and Adolescents in Jeddah, Saudi Arabia 吉达,沙特阿拉伯学校儿童和青少年体育活动与肥胖之间的关系
Pub Date : 2017-09-30 DOI: 10.4197/med.24-3.2
H. Elkhodary, D. Farsi
Citation Elkhodary HM, Farsi DJ. The association between physical activity and obesity among school children and adolescents in Jeddah, Saudi Arabia. JKAU Med Sci 2017; 24 (3): 13-27. DOI: 10.4197/Med. 24.3.2 Abstract Obesity aff ects children’s physical and psychological well-being. In this study we investigated the associations of obesity with physical activity, socioeconomic factors, and lifestyle among Saudi children and adolescents. A stratifi ed sample of 729 school children and 794 adolescent students was recruited. Waist circumference and body mass index were used to categorize the participants as obese and non-obese, and a structured mixed questionnaire was used to collect socioeconomic, physical activity, and lifestyle data. The results revealed that obese adolescent males (33.5%) were signifi cantly more common than obese adolescent females (13.6%, P < 0.001). Body mass index-based and waist circumference-based obesity was signifi cantly more common in private schools compared to public schools among school children and adolescents (P = 0.013 and P = 0.002, respectively). Student obesity was associated with higher parental education, especially among the school children (P = 0.006). Among adolescents, obesity was strongly associated with family income (P = 0.002) and time spent watching television (P = 0.004). Non-obese children and adolescents were considered subjectively more active than their obese counterparts (P < 0.001 and P = 0.011, respectively). In conclusion, obesity was common among school children and adolescents, and was associated with private schooling, adolescent male sex, parental education, and family income. Physical inactivity and time spent watching television were important risk factors for obesity among Saudi school children and adolescents.
引用Elkhodary HM, Farsi DJ。沙特阿拉伯吉达学龄儿童和青少年体育活动与肥胖之间的关系。中华医学会医学杂志2017;24(3): 13-27。DOI: 10.4197 /地中海。24.3.2摘要肥胖影响儿童的身心健康。在这项研究中,我们调查了沙特儿童和青少年中肥胖与身体活动、社会经济因素和生活方式的关系。对729名在校儿童和794名青少年学生进行了分层抽样调查。研究人员使用腰围和体重指数对参与者进行肥胖和非肥胖分类,并使用结构化混合问卷收集社会经济、身体活动和生活方式数据。结果显示,青少年男性肥胖率(33.5%)明显高于青少年女性肥胖率(13.6%,P < 0.001)。与公立学校相比,私立学校儿童和青少年中基于体重指数和腰围的肥胖明显更常见(P = 0.013和P = 0.002)。学生肥胖与父母教育程度较高有关,尤其是在校儿童(P = 0.006)。在青少年中,肥胖与家庭收入(P = 0.002)和看电视时间(P = 0.004)密切相关。非肥胖儿童和青少年被认为主观上比肥胖儿童和青少年更活跃(P分别< 0.001和P = 0.011)。综上所述,肥胖在学龄儿童和青少年中很常见,并且与私立学校教育、青春期男性、父母教育和家庭收入有关。缺乏体育活动和看电视的时间是沙特学龄儿童和青少年肥胖的重要危险因素。
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引用次数: 4
Findings in an Elderly Patient after a Fall 1例老年患者跌倒后的发现
Pub Date : 2017-09-30 DOI: 10.4197/med.24-3.5
Q. AlJabr
Citation Aljabr QM. Findings in an elderly patient after a fall. JKAU Med Sci 2017; 24 (3): 51-54. DOI: 10.4197/Med. 24.3.5 Abstract A 76-year-old male presented with neck pain beginning a month earlier, when he tripped over a ledge while exiting his truck. The patient landed on his face and lost consciousness. In the emergency room, the initial work up, including a head computed tomography scan, came back negative, but the fall work-up was incomplete. He was discharged with a physical therapy appointment to manage his neck pain but did not go. The patient’s pain continued for another four weeks before he went to the clinic. The pain was located at the midline of his posterior cervical spine with limited range of motion. He was otherwise asymptomatic. A more comprehensive fall assessment and work-up was completed. An immediate neck computed tomography scan was ordered and revealed subacute Stage 2 odontoid fractures. The patient was placed in a neck collar. An urgent appointment with the neurosurgery clinic was requested. The neurosurgeon reviewed the neck computed tomography scan; a follow up by magnetic resonance imaging confi rmed the fi ndings. After discussing treatment options, the patient agreed to proceed with fusion surgery. This case demonstrates the importance of performing a complete fall assessment and workup to ensure early detection and prevention of serious or life-threatening injuries.
引文Aljabr QM。一位老年病人跌倒后的发现。中华医学会医学杂志2017;24(3): 51-54。DOI: 10.4197 /地中海。24.3.5摘要一名76岁男性患者于1个月前因下车时被壁架绊倒而出现颈部疼痛。病人脸朝下摔了下来,失去了知觉。在急诊室,包括头部计算机断层扫描在内的初步检查结果为阴性,但秋季检查并不完整。他出院时预约了物理治疗以治疗颈部疼痛,但没有去。在他去诊所之前,病人的疼痛又持续了四个星期。疼痛位于颈椎后中线,活动范围有限。除此之外,他没有任何症状。完成了更全面的坠落评估和检查。立即进行颈部计算机断层扫描,发现亚急性2期齿状突骨折。病人被戴上颈圈。有人要求与神经外科诊所紧急预约。神经外科医生检查了颈部计算机断层扫描;后续的核磁共振成像证实了这一发现。在讨论了治疗方案后,患者同意进行融合手术。该病例证明了进行完整的跌倒评估和检查以确保早期发现和预防严重或危及生命的伤害的重要性。
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引用次数: 0
Neonatally Diagnosed Imperforate Hymen: Hymen Saving Surgery 新生儿诊断为处女膜闭锁:处女膜拯救手术
Pub Date : 2017-09-30 DOI: 10.4197/med.24-3.6
Maram A. Enani, W. O. Baamer, A. Aljohani, Shahad A. Aljohani, Noor A. Aljohani, Yousef M. Qazli, Ettedal A. Aljahdali
Citation Enani MA, Ba-Amer WO, Aljohani AS, Aljohani SA, Aljohani NA, Qazli YM, Aljahdali EA. Neonatally diagnosed imperforate hymen: hymen saving surgery. JKAU Med Sci 2017; 24 (3): 55-59. DOI: 10.4197/Med. 24.3.6 Abstract Imperforate hymen is the most common obstructive anomalies of the female genital tract. It is usually an isolated anomaly but can be rarely syndromic. It can be asymptomatic until puberty, but the diagnosis as early as neonatal period has been reported and as with our neonate with hematocolpos. The aim of this case report is to present the early diagnosis and treatment of a female neonate with imperforate hymen taking into consideration the religious and traditional value of preservation of virginity in our community, and to stress the importance of careful post birth examination of the neonate and early management to avoid complications of late diagnosis.
Enani MA, Ba-Amer WO, Aljohani AS, Aljohani SA, Aljohani NA, Qazli YM, Aljahdali EA。新生儿诊断为处女膜闭锁:处女膜挽救手术。中华医学会医学杂志2017;24(3): 55-59。DOI: 10.4197 /地中海。处女膜闭锁是女性生殖道最常见的梗阻性异常。它通常是一个孤立的异常,但可以很少综合征。它可以在青春期前无症状,但早在新生儿期就有诊断,正如我们的新生儿血性结肠一样。本病例报告的目的是在考虑到我们社区的宗教和传统贞操价值的基础上,介绍一名女性新生儿处女膜闭锁的早期诊断和治疗,并强调新生儿出生后仔细检查和早期处理的重要性,以避免晚期诊断并发症。
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引用次数: 0
Maternal Outcomes of Breastfeeding in King Abdulaziz University Hospital, Saudi Arabia 沙特阿拉伯阿卜杜勒阿齐兹国王大学医院母乳喂养的产妇结局
Pub Date : 2017-09-30 DOI: 10.4197/med.24-3.3
L. Banjar, H. Faruqui, A. Ghunaim, Amal Almalki, H. Alshaikh, M. Alsamti, H. Mosli
Citation Banjar LA, Faruqui HM, Ghunaim AH, Almalki AF, Alshaikh HM, Alsamti M, Mosli HH. Maternal outcomes of breastfeeding in King Abdulaziz University Hospital, Saudi Arabia. JKAU Med Sci 2017; 24 (3): 29-38. DOI: 10.4197/Med. 24.3.3 Abstract Breastfeeding has a great effi cacy on the growing infant, as well as the mother. It has been suggested that breastfeeding promotes postpartum weight loss. Furthermore, it may alter the risk of developing postpartum depression. The aim of this study is to further understand the adherence and the eff ect of breast milk feeding on developing a postpartum depression and calculating the postpartum weight reduction percentage in comparison to pre-pregnancy weight. A cross-sectional study was conducted in King Abdulaziz University Hospital among 153 mothers, whose infants are less than two years of age. Data were collected by interviewing the mothers using a standard questionnaire designed for the study and the HAMD depression scale with anthropometric measures. 85.62% of the study sample had breastfed, 43.38% breastfed for 1 to 2 months, and 24.18% for 6 months or more. However, the relationship of postpartum depression and breastfeeding was not signifi cant with a P-value > 0.05. 84.97% of the included mothers had the same or greater weight than before pregnancy. In conclusion, mothers in King Abdulaziz University Hospital are well adherent to breast milk feeding. The association of breastfeeding to weight loss was not observed as suggested. Mothers with postpartum depression were less adherent to the practice of breastfeeding.
引用Banjar LA, Faruqui HM, Ghunaim AH, Almalki AF, Alshaikh HM, Alsamti M, Mosli HH。沙特阿拉伯阿卜杜勒阿齐兹国王大学医院母乳喂养的产妇结局。中华医学会医学杂志2017;24(3): 29-38。DOI: 10.4197 /地中海。24.3.3摘要母乳喂养对生长中的婴儿和母亲都有很大的功效。有人建议母乳喂养可以促进产后体重减轻。此外,它可能会改变患产后抑郁症的风险。本研究的目的是进一步了解母乳喂养的依从性和对产后抑郁症的影响,并计算产后体重与孕前体重的下降百分比。在阿卜杜勒阿齐兹国王大学医院对153名婴儿不满两岁的母亲进行了横断面研究。数据是通过使用为研究设计的标准问卷和HAMD抑郁量表与人体测量法对母亲进行访谈来收集的。85.62%的研究样本母乳喂养,43.38%母乳喂养1 ~ 2个月,24.18%母乳喂养6个月及以上。而产后抑郁与母乳喂养的关系不显著,p值> 0.05。84.97%的孕妇体重与孕前相同或增加。总之,阿卜杜勒阿齐兹国王大学医院的母亲很好地坚持母乳喂养。母乳喂养与体重减轻之间的联系并没有被观察到。患有产后抑郁症的母亲很少坚持母乳喂养。
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引用次数: 0
Vaginal Colonization by Escherichia coli in Pregnant Women at King Abdulaziz University Hospital, Jeddah, Saudi Arabia 沙特阿拉伯吉达阿卜杜勒阿齐兹国王大学医院孕妇阴道内大肠杆菌定植
Pub Date : 2017-09-30 DOI: 10.4197/med.24-3.4
Taghreed J. Jamal, H. Younus, H. Abduljabbar, A. Jiman-Fatani, Amal F. Makled
Citation Jamal TY, Younus HA, Abduljabbar HS, Fatani AA, Makled AF. Vaginal colonization by Escherichia coli in pregnant women at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. JKAU Med Sci 2017; 24 (3): 39-49. DOI: 10.4197/Med. 24.3.4 Abstract Maternal and neonatal infections by Escherichia coli remain a challenging problem for obstetricians and pediatricians. This study aims to determine the prevalence of vaginal colonization by Escherichia coli among pregnant women attending the Antenatal Clinics at King Abdulaziz University Hospital in JeddahSaudi Arabia, and to investigate the susceptibility of isolated Escherichia coli to the most commonly used antimicrobials. In this study, 100 pregnant women in the last trimester and 25 non-pregnant women were screened for vaginal colonization of Escherichia coli. The suspected colonies were identifi ed by conventional methods and were confi rmed by automated technology "Vitek 2 System". Also, antimicrobial susceptibility tests were done by the same methods". Escherichia coli isolates were serotyped to detect the presence of K1 antigen. Out of 100 pregnant women in the last trimester; twenty-one (21%) were Escherichia coli positive. Also, out of 25 non-pregnant women; four (16%) were Escherichia coli-positive. All of the isolated Escherichia coli were susceptible to most antimicrobial agents. The percentage of vaginal Escherichia coli resistance to trimethoprim/sulfamethoxazole, ampicillin and piperacillin ranged from 38.1% to 42.9%. The virulence factor K1 antigen was demonstrated in 42.9% of Escherichia coli -positive pregnant women.
引自Jamal TY, Younus HA, Abduljabbar HS, Fatani AA, Makled AF.沙特阿拉伯吉达阿卜杜勒阿齐兹国王大学医院孕妇阴道大肠杆菌定植。中华医学会医学杂志2017;24(3): 39-49。DOI: 10.4197 /地中海。24.3.4摘要孕产妇和新生儿大肠杆菌感染仍然是妇产科医生面临的一个具有挑战性的问题。本研究旨在确定在沙特阿拉伯吉达阿卜杜勒阿齐兹国王大学医院产前诊所就诊的孕妇阴道定植大肠杆菌的流行情况,并调查分离的大肠杆菌对最常用抗菌素的敏感性。在这项研究中,对100名孕晚期孕妇和25名非孕妇进行了阴道大肠杆菌定植筛查。用常规方法鉴定可疑菌落,并用自动化技术“Vitek 2 System”进行确认。此外,用同样的方法进行了抗菌药物敏感性试验。对分离的大肠杆菌进行血清分型,检测是否存在K1抗原。在最后三个月的100名孕妇中;大肠杆菌阳性21例(21%)。另外,在25名未怀孕的妇女中;4例(16%)大肠杆菌阳性。所有分离的大肠杆菌对大多数抗菌药物均敏感。阴道大肠杆菌对甲氧苄啶/磺胺甲恶唑、氨苄西林、哌拉西林的耐药比例为38.1% ~ 42.9%。42.9%的大肠杆菌阳性孕妇存在毒力因子K1抗原。
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引用次数: 0
Frequency of Breast Cancer Surgery Related Arm Lymphedema at King Abdulaziz University Hospital 2008 – 2015, a Tertiary Center Experience, Jeddah, Saudi Arabia 2008 - 2015年阿卜杜勒阿齐兹国王大学医院乳腺癌手术相关上臂淋巴水肿的频率,沙特阿拉伯吉达三级中心经验
Pub Date : 2017-06-30 DOI: 10.4197/MED.24-2.3
Sabah S. Moshref, Y. Jamal, Zuhoor K. Al Gaithy, S. Alkhayyat, B. Awan, M. Fakiha, H. Ammar, Abdullah Bamashmos, Mawaddah Alrajraji, Mohammad Abolhamayl
The purpose of this retrospective study was to investigate the frequency of breast cancer-related lymphedema at King Abdulaziz University Hospital and factors associated with it. Eighty-four breast cancer-related lymphedema patients were recruited from Plastic and Reconstruction Surgery Unit, King Abdulaziz University Hospital, Jeddah, Saudi Arabia after breast cancer treatment during the period from 2008 till 2015. According to the circumference difference between healthy and affected arm, lymphedema degree was categorized into mild (> 5-10%), moderate (> 10-15%) and severe (> 15%). From a total of 598 patients who underwent breast cancer resection, 84 (14.05%) patients developed breast cancer-related lymphedema. In out of the 84 patients who developed arm lymphedema, the treatment was mostly modified radical mastectomy and radiotherapy (n = 59, 70.24%); followed by lumpectomy plus axillary lymph node dissection and radiotherapy (n = 18, 21.43%), simple mastectomy (n = 5, 5.95%) and lumpectomy with sentinel lymph node dissection and radiotherapy (n = 2, 2.38%) with statistical significant difference between them (P = 0.0001). The frequency of lymphedema in our institution is 14.05%. It is mostly moderate, appears during the 1st year after surgery in patients who underwent modified radical mastectomy and radiotherapy, aged more than 60 years and obese.
本回顾性研究的目的是调查阿卜杜勒阿齐兹国王大学医院乳腺癌相关淋巴水肿的发生率及其相关因素。2008年至2015年,在沙特阿拉伯吉达阿卜杜勒阿齐兹国王大学医院整形与重建外科部门接受乳腺癌治疗的乳腺癌相关淋巴水肿患者84例。根据正常臂与患臂围度差异,将淋巴水肿程度分为轻度(> 5-10%)、中度(> 10-15%)和重度(> 15%)。在598例接受乳腺癌切除术的患者中,84例(14.05%)患者出现乳腺癌相关淋巴水肿。在84例发生上肢淋巴水肿的患者中,治疗主要是改良根治性乳房切除术和放疗(n = 59, 70.24%);其次是乳房肿瘤切除+腋窝淋巴结清扫+放疗(n = 18, 21.43%)、单纯乳房切除术(n = 5, 5.95%)和乳房肿瘤切除+前哨淋巴结清扫+放疗(n = 2, 2.38%),差异有统计学意义(P = 0.0001)。本院淋巴水肿发生率为14.05%。它大多是中度的,出现在手术后第一年接受改良根治性乳房切除术和放疗的患者中,年龄超过60岁,肥胖。
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引用次数: 4
期刊
Journal of King Abdulaziz University-medical Sciences
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