M. Alnuaimi, A. Siddiqua, A. Aljaberi, J. Alkaabi, Khaled M. Aldahmani, B. Afandi, R. Almazrouei
Background: COVID19 infection is associated with worse outcomes in patients admitted with diabetic ketoacidosis (DKA). The indirect impact of the pandemic on DKA admissions to COVID19 free hospitals has not been evaluated. In this study, we evaluate the characteristics and outcomes of DKA admissions before and during the pandemic. Materials and Methods: This retrospective study included 146 episodes of DKA for patients aged 16 years and above admitted to Tawam Hospital, A COVID-19-free hospital, between April and October from 2017 to 2020. Sociodemographic, clinical, and laboratory data were retrieved from the electronic records. Data from the (2017–2019) period were compared to those during the COVID19 pandemic in 2020. Results: We evaluated 79 pre-COVID19 and 67 during the COVID19 admissions. During the pandemic, patients were older (30 vs. 23 years, P 0.2) with higher proportions of male sex (66% vs. 25%) and non-Emirati nationals (Arabs 17.9% vs. 12.7% and South Asian 20.9% vs. 3.8%). In addition, only 64.2% of patients had medical coverage compared to 92.4% in pre-COVID19 time. More patients with newly diagnosed diabetes (25.4% vs. 7.6%) and type 2 diabetes mellitus (32.8% vs. 17.7%) were encountered during the pandemic. Overall, there was no significant difference in severity, time to resolution, and mortality. Length of stay was longer for DKA admissions during the pandemic (4 vs. 3 days). Conclusion: In our COVID19-free hospital, the pandemic has led to an increased rate of DKA admissions and significant change in the sociodemographic characteristics of patients with DKA. Clinical care, patients' management, and outcomes were not adversely affected. Assessing the indirect impact of the pandemic is essential for future service planning.
{"title":"The impact of the COVID-19 pandemic on diabetic ketoacidosis admissions to a COVID-19-free hospital","authors":"M. Alnuaimi, A. Siddiqua, A. Aljaberi, J. Alkaabi, Khaled M. Aldahmani, B. Afandi, R. Almazrouei","doi":"10.4103/jdep.jdep_45_21","DOIUrl":"https://doi.org/10.4103/jdep.jdep_45_21","url":null,"abstract":"Background: COVID19 infection is associated with worse outcomes in patients admitted with diabetic ketoacidosis (DKA). The indirect impact of the pandemic on DKA admissions to COVID19 free hospitals has not been evaluated. In this study, we evaluate the characteristics and outcomes of DKA admissions before and during the pandemic. Materials and Methods: This retrospective study included 146 episodes of DKA for patients aged 16 years and above admitted to Tawam Hospital, A COVID-19-free hospital, between April and October from 2017 to 2020. Sociodemographic, clinical, and laboratory data were retrieved from the electronic records. Data from the (2017–2019) period were compared to those during the COVID19 pandemic in 2020. Results: We evaluated 79 pre-COVID19 and 67 during the COVID19 admissions. During the pandemic, patients were older (30 vs. 23 years, P 0.2) with higher proportions of male sex (66% vs. 25%) and non-Emirati nationals (Arabs 17.9% vs. 12.7% and South Asian 20.9% vs. 3.8%). In addition, only 64.2% of patients had medical coverage compared to 92.4% in pre-COVID19 time. More patients with newly diagnosed diabetes (25.4% vs. 7.6%) and type 2 diabetes mellitus (32.8% vs. 17.7%) were encountered during the pandemic. Overall, there was no significant difference in severity, time to resolution, and mortality. Length of stay was longer for DKA admissions during the pandemic (4 vs. 3 days). Conclusion: In our COVID19-free hospital, the pandemic has led to an increased rate of DKA admissions and significant change in the sociodemographic characteristics of patients with DKA. Clinical care, patients' management, and outcomes were not adversely affected. Assessing the indirect impact of the pandemic is essential for future service planning.","PeriodicalId":294186,"journal":{"name":"Journal of Diabetes and Endocrine Practice","volume":"135 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129830865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Dahmani, B. Afandi, N. Aljohani, Ali Al Mamari, T. Elhadd, W. Hussein, Yousef Saleh, Nasreen Alsayed, Aljuhani Rajallah
These are the advance abstracts of the Clinical Congress (Virtual) of the Gulf Association of Endocrinology and Diabetes held on October 7–9, 2021. The declared educational objectives of the congress were to give a “state of the art in endocrine practice.” Plenary and symposia presentations were delivered online by international and regional key opinion leaders. In addition, free communications on current research and clinical practice in the region and worldwide were presented online. We present here the abstracts of the congress as submitted by the authors of the free communications after minimal restyling and editing to suit the publication requirements of the Journal. We hope that by publishing them in our open access journal, we provide an early recognition of the work and extend the benefit to those who could not make it to the live presentations. Background: Hypogonadism is the most common form of hypopituitarism in men with macroprolactinoma, but factors related to hypogonadism recovery are limited. Objectives: We aimed to study the prevalence of hypogonadism in men with macroprolactinoma exclusively treated with dopamine agonists and assess factors predicting hypogonadism recovery. Methods: A multicenter retrospective study of men with macroprolactinoma identified using ICD 9 and 10 codes and treated between 2009 and 2019 in five centers in the United Arab Emirates and the Kingdom of Saudi Arabia. Hypogonadism defined as low testosterone level with normal or low gonadotropins being evaluated at presentation and at the last clinic visit. Results: A total of 101 patients (mean age 33 years) were initially included in the study. The most common symptoms at presentation were headache (75.3%), erectile dysfunction, low, and libido. Median tumor size at diagnosis was 2.7 cm. Of 82 patients with available data, 62 (75.6%) had evidence of hypogonadism at baseline. The prevalence of growth hormone deficiency and hypothyroidism was 35.9% and 32.5%, respectively. The median (interquartile range [IQR]) serum prolactin level (PRL), available in 83 patients, was 20,000 (56,293.6) miU/l, with a median serum total testosterone (TT) level of 4.4 (5.3) nmol/l. Most patients were treated with cabergoline ( n =, %), with a median (IQR) duration of 6 (4) years. Follow‑up data on hypogonadism status were available on 60 out of 62 patients. Of those, 39 patients (65%) recovered their pituitary–gonadal Objective: There are limited longitudinal studies assessing the risk factors associated with the evolution of diabetic peripheral neuropathy (DPN). M ethods: Patients with type 2 diabetes (T2D) ( n = 78) and control participants ( n = 26) underwent clinical, metabolic, and neuropathy phenotyping using corneal confocal microscopy (CCM), vibration perception threshold (VPT), and DN4 questionnaire at baseline and 2‑year follow‑up. Results: The prevalence of DPN and painful DPN was 18% and 26%, respectively. Patients with T2D had a higher VPT ( P ≤ 0.01) and lower co
{"title":"Free communications of the gulf association of endocrinology and diabetes virtual meeting 2021 - October 7–9, 2021","authors":"K. Dahmani, B. Afandi, N. Aljohani, Ali Al Mamari, T. Elhadd, W. Hussein, Yousef Saleh, Nasreen Alsayed, Aljuhani Rajallah","doi":"10.4103/jdep.jdep_41_21","DOIUrl":"https://doi.org/10.4103/jdep.jdep_41_21","url":null,"abstract":"These are the advance abstracts of the Clinical Congress (Virtual) of the Gulf Association of Endocrinology and Diabetes held on October 7–9, 2021. The declared educational objectives of the congress were to give a “state of the art in endocrine practice.” Plenary and symposia presentations were delivered online by international and regional key opinion leaders. In addition, free communications on current research and clinical practice in the region and worldwide were presented online. We present here the abstracts of the congress as submitted by the authors of the free communications after minimal restyling and editing to suit the publication requirements of the Journal. We hope that by publishing them in our open access journal, we provide an early recognition of the work and extend the benefit to those who could not make it to the live presentations. Background: Hypogonadism is the most common form of hypopituitarism in men with macroprolactinoma, but factors related to hypogonadism recovery are limited. Objectives: We aimed to study the prevalence of hypogonadism in men with macroprolactinoma exclusively treated with dopamine agonists and assess factors predicting hypogonadism recovery. Methods: A multicenter retrospective study of men with macroprolactinoma identified using ICD 9 and 10 codes and treated between 2009 and 2019 in five centers in the United Arab Emirates and the Kingdom of Saudi Arabia. Hypogonadism defined as low testosterone level with normal or low gonadotropins being evaluated at presentation and at the last clinic visit. Results: A total of 101 patients (mean age 33 years) were initially included in the study. The most common symptoms at presentation were headache (75.3%), erectile dysfunction, low, and libido. Median tumor size at diagnosis was 2.7 cm. Of 82 patients with available data, 62 (75.6%) had evidence of hypogonadism at baseline. The prevalence of growth hormone deficiency and hypothyroidism was 35.9% and 32.5%, respectively. The median (interquartile range [IQR]) serum prolactin level (PRL), available in 83 patients, was 20,000 (56,293.6) miU/l, with a median serum total testosterone (TT) level of 4.4 (5.3) nmol/l. Most patients were treated with cabergoline ( n =, %), with a median (IQR) duration of 6 (4) years. Follow‑up data on hypogonadism status were available on 60 out of 62 patients. Of those, 39 patients (65%) recovered their pituitary–gonadal Objective: There are limited longitudinal studies assessing the risk factors associated with the evolution of diabetic peripheral neuropathy (DPN). M ethods: Patients with type 2 diabetes (T2D) ( n = 78) and control participants ( n = 26) underwent clinical, metabolic, and neuropathy phenotyping using corneal confocal microscopy (CCM), vibration perception threshold (VPT), and DN4 questionnaire at baseline and 2‑year follow‑up. Results: The prevalence of DPN and painful DPN was 18% and 26%, respectively. Patients with T2D had a higher VPT ( P ≤ 0.01) and lower co","PeriodicalId":294186,"journal":{"name":"Journal of Diabetes and Endocrine Practice","volume":"261 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133570964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Muammar, J. Smyth, O. Aldaleel, Salah E. Gashout, M. Jamieson
Background: Despite the increasing demand for continuous subcutaneous insulin infusion (CSII) or insulin pump therapy in preschool children with Type 1 diabetes (T1D), reports on its advantages over conventional methods, particularly multiple dose injection (MDI) therapy, are scant. Objectives: We aimed to investigate the effectiveness, safety, and parental satisfaction of using CSII compared to MDI in preschool children with T1D. This study also seeks to establish criteria to help clinicians choose patients most suitable for CSII. Methods: Relevant terms based on the study outcomes were used to search electronic databases and manual search for the literature. Selected articles were then thoroughly reviewed and evaluated. Results: The effect in the meta-analysis showed a small, nonsignificant positive effect on HbA1c of the CSII compared to the MDI insulin intervention method (mean Cohen's d effect size = 0.25, Standard Error = 0.18, P = 0.16 (n = 127)) and a small, nonsignificant negative effect on safety of the CSII compared to the MDI insulin intervention method (mean Cohen's d effect size = −0.26, SE = 0.36, P = 0.47 [n = 70]). For parental satisfaction, data were small and therefore inappropriate for meta-analysis. Conclusion: For preschool children, the effectiveness and safety of insulin pump therapy compared with MDI therapy was considered statistically nonsignificant. All preschool children with T1D can be considered potentially eligible candidates for insulin pump therapy. Suggested selection criteria to apply when considering preschool children for insulin pump therapy were presented.
{"title":"Effectiveness, safety, and parental satisfaction of insulin pump therapy versus multiple-dose injection therapy in preschool children with type 1 diabetes: A systematic review and meta-analysis","authors":"T. Muammar, J. Smyth, O. Aldaleel, Salah E. Gashout, M. Jamieson","doi":"10.4103/jdep.jdep_36_21","DOIUrl":"https://doi.org/10.4103/jdep.jdep_36_21","url":null,"abstract":"Background: Despite the increasing demand for continuous subcutaneous insulin infusion (CSII) or insulin pump therapy in preschool children with Type 1 diabetes (T1D), reports on its advantages over conventional methods, particularly multiple dose injection (MDI) therapy, are scant. Objectives: We aimed to investigate the effectiveness, safety, and parental satisfaction of using CSII compared to MDI in preschool children with T1D. This study also seeks to establish criteria to help clinicians choose patients most suitable for CSII. Methods: Relevant terms based on the study outcomes were used to search electronic databases and manual search for the literature. Selected articles were then thoroughly reviewed and evaluated. Results: The effect in the meta-analysis showed a small, nonsignificant positive effect on HbA1c of the CSII compared to the MDI insulin intervention method (mean Cohen's d effect size = 0.25, Standard Error = 0.18, P = 0.16 (n = 127)) and a small, nonsignificant negative effect on safety of the CSII compared to the MDI insulin intervention method (mean Cohen's d effect size = −0.26, SE = 0.36, P = 0.47 [n = 70]). For parental satisfaction, data were small and therefore inappropriate for meta-analysis. Conclusion: For preschool children, the effectiveness and safety of insulin pump therapy compared with MDI therapy was considered statistically nonsignificant. All preschool children with T1D can be considered potentially eligible candidates for insulin pump therapy. Suggested selection criteria to apply when considering preschool children for insulin pump therapy were presented.","PeriodicalId":294186,"journal":{"name":"Journal of Diabetes and Endocrine Practice","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114169463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: We sought to scope the practices in managing thyroid nodules in the Middle East and Africa (MEA). Materials and Methods: Survey of a convenience sample of physicians concerned with the management of thyroid disease. Results: Two hundred and twelve responses are included. Fine needle aspiration (FNA) is performed chiefly using ultrasound guidance (74.9%), generally by radiologists (47.1%). Respondents have a lower threshold for FNA than recommended. Management depends on the FNA cytology, with the follicular lesion of undetermined significance/atypia of undetermined significance resulting in repeat FNA for cytology (40.7%), immediate referral for thyroid surgery (32.9%), or molecular testing (13.2%). Follicular neoplasms are referred for lobectomy or total thyroidectomy by 81.6% of respondents. Nodules suspicious for malignancy are referred for thyroid surgery by 76.6% and for molecular testing by 20.1%. Respondents are less likely to perform FNA in an octogenarian than a younger patient with a comparable nodule. For a multinodular goiter, 29.9%, 25.9%, or 17.8% of respondents would, respectively, sample the largest 2–3 nodules, single largest nodule, or all nodules >1 cm in size. During pregnancy, respondents would perform FNA with nodular growth (27.1%) in the absence of nodular growth (25.6%), but more respondents (35.2%) would defer FNA until after pregnancy. Conclusions: The physicians' survey revealed a practice pattern in managing thyroid nodules in the MEA region, including both agreements and deviations from current guidelines. Focused quality assurance exercises, education, and research are needed.
{"title":"Clinical practice patterns in the management of thyroid nodules: The first survey from the Middle East and Africa","authors":"S. Beshyah, Aly B Khalil","doi":"10.4103/jdep.jdep_34_21","DOIUrl":"https://doi.org/10.4103/jdep.jdep_34_21","url":null,"abstract":"Objective: We sought to scope the practices in managing thyroid nodules in the Middle East and Africa (MEA). Materials and Methods: Survey of a convenience sample of physicians concerned with the management of thyroid disease. Results: Two hundred and twelve responses are included. Fine needle aspiration (FNA) is performed chiefly using ultrasound guidance (74.9%), generally by radiologists (47.1%). Respondents have a lower threshold for FNA than recommended. Management depends on the FNA cytology, with the follicular lesion of undetermined significance/atypia of undetermined significance resulting in repeat FNA for cytology (40.7%), immediate referral for thyroid surgery (32.9%), or molecular testing (13.2%). Follicular neoplasms are referred for lobectomy or total thyroidectomy by 81.6% of respondents. Nodules suspicious for malignancy are referred for thyroid surgery by 76.6% and for molecular testing by 20.1%. Respondents are less likely to perform FNA in an octogenarian than a younger patient with a comparable nodule. For a multinodular goiter, 29.9%, 25.9%, or 17.8% of respondents would, respectively, sample the largest 2–3 nodules, single largest nodule, or all nodules >1 cm in size. During pregnancy, respondents would perform FNA with nodular growth (27.1%) in the absence of nodular growth (25.6%), but more respondents (35.2%) would defer FNA until after pregnancy. Conclusions: The physicians' survey revealed a practice pattern in managing thyroid nodules in the MEA region, including both agreements and deviations from current guidelines. Focused quality assurance exercises, education, and research are needed.","PeriodicalId":294186,"journal":{"name":"Journal of Diabetes and Endocrine Practice","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132980282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmad M J Saad, Z. Younes, Alaa M. Abuali, M. Farooqi, A. Hassoun
Purpose: The purpose of this study is to identify the rates of diabetes distress and depression in patients with Type 2 diabetes and to explore the relationship between glycemic control, depression, and diabetes distress. Patients and Methods: One hundred and fifteen adults with Type 2 diabetes were recruited for this cross-sectional study from the Dubai Diabetes Center in Dubai, United Arab Emirates. The Arabic version of the Diabetes Distress Scale was used to assess diabetes distress, and the Arabic version of the Beck Depression Inventory-II scale was used to assess depression symptoms. Results: Our study population consisted of 63 males (54.8%) and 52 females (45.2%). We found that, out of this study population, 54.3% had uncontrolled diabetes with glycosylated hemoglobin (HbA1c) >7% (53 mmol/mol), 54.8% exhibited diabetes distress, and 29.6% showed depression. Using a combined oral and insulin treatment was found to be significant independent predictors of poor glycemic control as defined by an HbA1c >7% (53 mmol/mol). Conclusion: This study has identified psychosocial issues as a significant health problem among adult patients with type 2 diabetes and offers data confirming the relevance of diabetes distress and depression among them. This finding can help clinicians have a better understanding of the extent to which psychosocial issues influence diabetes management so as to develop effective and appropriate treatment approaches.
{"title":"Diabetes distress and depression among patients with type 2 diabetes: A cross-sectional study","authors":"Ahmad M J Saad, Z. Younes, Alaa M. Abuali, M. Farooqi, A. Hassoun","doi":"10.4103/jdep.jdep_32_21","DOIUrl":"https://doi.org/10.4103/jdep.jdep_32_21","url":null,"abstract":"Purpose: The purpose of this study is to identify the rates of diabetes distress and depression in patients with Type 2 diabetes and to explore the relationship between glycemic control, depression, and diabetes distress. Patients and Methods: One hundred and fifteen adults with Type 2 diabetes were recruited for this cross-sectional study from the Dubai Diabetes Center in Dubai, United Arab Emirates. The Arabic version of the Diabetes Distress Scale was used to assess diabetes distress, and the Arabic version of the Beck Depression Inventory-II scale was used to assess depression symptoms. Results: Our study population consisted of 63 males (54.8%) and 52 females (45.2%). We found that, out of this study population, 54.3% had uncontrolled diabetes with glycosylated hemoglobin (HbA1c) >7% (53 mmol/mol), 54.8% exhibited diabetes distress, and 29.6% showed depression. Using a combined oral and insulin treatment was found to be significant independent predictors of poor glycemic control as defined by an HbA1c >7% (53 mmol/mol). Conclusion: This study has identified psychosocial issues as a significant health problem among adult patients with type 2 diabetes and offers data confirming the relevance of diabetes distress and depression among them. This finding can help clinicians have a better understanding of the extent to which psychosocial issues influence diabetes management so as to develop effective and appropriate treatment approaches.","PeriodicalId":294186,"journal":{"name":"Journal of Diabetes and Endocrine Practice","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122133164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Alsaffar, Azza Al Shidhani, Aala Zadjali, Zayana Hameed, Irfan Ullah, Almundher Al Maawali
Multiple factors control the growth of a child, including genetics, nutrition, and socioeconomic factors. Referral of tallboys who are otherwise well is very rare. However, sometimes, extraordinary tall stature for the age can be a cause of great concern to the parents. We report a case of an Omani child with a de novo mutation of NSD1 that led to his overgrowth and diagnosis of Sotos syndrome (SoS). This syndrome is a rare genetic disorder. Only two cases of genetically proven diagnosis were reported from the Middle East and North Africa region. Therefore, we describe a case and highlight the comorbidities associated with this condition, encouraging colleagues from the region to report their cases to understand better the phenotype–genotype and the natural history of this disorder in this part of the world.
{"title":"De novo NSD1 mutation leading to Sotos syndrome – First case report from Oman","authors":"H. Alsaffar, Azza Al Shidhani, Aala Zadjali, Zayana Hameed, Irfan Ullah, Almundher Al Maawali","doi":"10.4103/jdep.jdep_30_21","DOIUrl":"https://doi.org/10.4103/jdep.jdep_30_21","url":null,"abstract":"Multiple factors control the growth of a child, including genetics, nutrition, and socioeconomic factors. Referral of tallboys who are otherwise well is very rare. However, sometimes, extraordinary tall stature for the age can be a cause of great concern to the parents. We report a case of an Omani child with a de novo mutation of NSD1 that led to his overgrowth and diagnosis of Sotos syndrome (SoS). This syndrome is a rare genetic disorder. Only two cases of genetically proven diagnosis were reported from the Middle East and North Africa region. Therefore, we describe a case and highlight the comorbidities associated with this condition, encouraging colleagues from the region to report their cases to understand better the phenotype–genotype and the natural history of this disorder in this part of the world.","PeriodicalId":294186,"journal":{"name":"Journal of Diabetes and Endocrine Practice","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130951926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of adrenal insufficiency","authors":"S. Hussain, S. Hussain, N. Ghouri, K. Meeran","doi":"10.4103/jdep.jdep_42_21","DOIUrl":"https://doi.org/10.4103/jdep.jdep_42_21","url":null,"abstract":"","PeriodicalId":294186,"journal":{"name":"Journal of Diabetes and Endocrine Practice","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128484795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Treatment of adrenal insufficiency (AI) requires correct lifelong use of glucocorticoids (GCs) with early dose adjustments to cover the increased demand in stress to avoid life-threatening emergencies. Objectives: We determine the current specific knowledge of physicians in a convenience sample on the pathophysiological and clinical aspects of AI in the two regions of North Africa and the Middle East. Materials and Methods: Participants (n = 96) were invited to complete an electronic questionnaire with various possible answers on the subject of multiple-choice questions covering physiology, pharmacology, and clinical management and define respondents' professional profiles. Results: The present study suggests that in the investigated settings, physicians' knowledge of physiology and pharmacology GCs, medical replacement strategies in AI, and prevention of adrenal crisis may be insufficient. Great knowledge gaps were demonstrated. Conclusions: There is a need for continuous structured education and training on AI in both general medical and endocrine forums.
{"title":"Management of adrenal insufficiency: A survey of perceptions and practices of physicians from the Middle East and North Africa","authors":"S. Beshyah, K. Ali","doi":"10.4103/jdep.jdep_12_21","DOIUrl":"https://doi.org/10.4103/jdep.jdep_12_21","url":null,"abstract":"Introduction: Treatment of adrenal insufficiency (AI) requires correct lifelong use of glucocorticoids (GCs) with early dose adjustments to cover the increased demand in stress to avoid life-threatening emergencies. Objectives: We determine the current specific knowledge of physicians in a convenience sample on the pathophysiological and clinical aspects of AI in the two regions of North Africa and the Middle East. Materials and Methods: Participants (n = 96) were invited to complete an electronic questionnaire with various possible answers on the subject of multiple-choice questions covering physiology, pharmacology, and clinical management and define respondents' professional profiles. Results: The present study suggests that in the investigated settings, physicians' knowledge of physiology and pharmacology GCs, medical replacement strategies in AI, and prevention of adrenal crisis may be insufficient. Great knowledge gaps were demonstrated. Conclusions: There is a need for continuous structured education and training on AI in both general medical and endocrine forums.","PeriodicalId":294186,"journal":{"name":"Journal of Diabetes and Endocrine Practice","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126353492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yumn H Shilli, S. Samargandy, Abdulrahman H. Shilli, Salwa I Bakhsh, R. Daghistani, Shady Alkayyat, H. Marzouki
Primary thyroid lymphoma (PTL) comprises 5% of all thyroid malignancies. In this case series, we aim to review its clinical presentation, diagnosis, and treatment. We included five PTL patients. All were females (mean age of 59.8 years). All patients presented with a rapidly growing neck swelling, and only two had obstructive symptoms. All patients had solitary masses, aside from one patient who had two lesions. All were causing mass effect and two with invasion of the surrounding tissue. All were diagnosed with diffuse large B-cell lymphoma. Cytology examination for PTL demonstrates atypical lymphoid cells. Four patients in our series had chemotherapy and currently in remission. The fifth died early after the clinical presentation. Two had thyroid surgeries.
{"title":"Thyroid lymphoma: Correlation of clinical, radiological, and pathological features","authors":"Yumn H Shilli, S. Samargandy, Abdulrahman H. Shilli, Salwa I Bakhsh, R. Daghistani, Shady Alkayyat, H. Marzouki","doi":"10.4103/jdep.jdep_24_21","DOIUrl":"https://doi.org/10.4103/jdep.jdep_24_21","url":null,"abstract":"Primary thyroid lymphoma (PTL) comprises 5% of all thyroid malignancies. In this case series, we aim to review its clinical presentation, diagnosis, and treatment. We included five PTL patients. All were females (mean age of 59.8 years). All patients presented with a rapidly growing neck swelling, and only two had obstructive symptoms. All patients had solitary masses, aside from one patient who had two lesions. All were causing mass effect and two with invasion of the surrounding tissue. All were diagnosed with diffuse large B-cell lymphoma. Cytology examination for PTL demonstrates atypical lymphoid cells. Four patients in our series had chemotherapy and currently in remission. The fifth died early after the clinical presentation. Two had thyroid surgeries.","PeriodicalId":294186,"journal":{"name":"Journal of Diabetes and Endocrine Practice","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134641608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID-19 and the pituitary gland","authors":"Kanchana Ngaosuwan, D. Johnston","doi":"10.4103/jdep.jdep_43_21","DOIUrl":"https://doi.org/10.4103/jdep.jdep_43_21","url":null,"abstract":"","PeriodicalId":294186,"journal":{"name":"Journal of Diabetes and Endocrine Practice","volume":"16 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132609279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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