Pub Date : 2014-07-01DOI: 10.4103/2230-7095.149774
Sunil Kukreja, K. Sharma
Osteochondroma is the most common benign bone tumor and often diagnosed as an incidental finding. Most are asymptomatic, however significant pain, and pressure symptoms warrant excision. Most common location of solitary exostosis is metaphysics around the knee. We are reporting a case of a 14-year-old boy who presented with a swelling over the anterior aspect just below the mid-thigh level on the right side. Characteristic radiological features of exostosis were documented on plain radiograph and magnetic resonance imaging. Growth was excised, and diagnosis of solitary exostosis arising from diaphyseal region was confirmed on histopathology examination. This case report documents the uncommon diaphyseal location of solitary exostosis in an adolescent. Symptomatic lesions warrant excision.
{"title":"Solitary diaphyseal exostosis of femur: case report of an uncommon presentation","authors":"Sunil Kukreja, K. Sharma","doi":"10.4103/2230-7095.149774","DOIUrl":"https://doi.org/10.4103/2230-7095.149774","url":null,"abstract":"Osteochondroma is the most common benign bone tumor and often diagnosed as an incidental finding. Most are asymptomatic, however significant pain, and pressure symptoms warrant excision. Most common location of solitary exostosis is metaphysics around the knee. We are reporting a case of a 14-year-old boy who presented with a swelling over the anterior aspect just below the mid-thigh level on the right side. Characteristic radiological features of exostosis were documented on plain radiograph and magnetic resonance imaging. Growth was excised, and diagnosis of solitary exostosis arising from diaphyseal region was confirmed on histopathology examination. This case report documents the uncommon diaphyseal location of solitary exostosis in an adolescent. Symptomatic lesions warrant excision.","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132052928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-07-01DOI: 10.4103/2230-7095.149764
S. Bir, P. Kalakoti, S. Ambekar, Papireddy Bollam, A. Nanda
Introduction: The association between ABO blood groups and intracranial aneurysms is not well-understood. Many co-morbid factors are associated with intracranial aneurysms. The prevalence of different blood groups and associations with the risk factors in patients with intracranial aneurysms are reviewed. Methodology: A retrospective analysis was conducted on patients presenting with intracranial aneurysms and undergoing active neurosurgical intervention at the Louisiana State University Health Sciences Center between 1 st January 1993 and 31 st December 2012. A total of 1248 patients were identified for the analysis. Data pertaining to demographics and clinical characteristics of these patients were extracted from the electronic patient records by two authors independently. A univariate and multivariate analysis was performed to investigate the association of ABO blood groups with risk factors in patients with intracranial aneurysms. Results: The most common ABO blood group in our study population was O (543 cases, 43.5%), followed by group A (525 cases, 42%). Blood group A (46% vs. 35.5% patients; P = 0.01) and blood group B (18% vs. 7% patients; P = 0.000) were significantly associated with the development of intracranial aneurysms in Caucasians and African Americans, respectively. We found smoking ( P = 0.01) and hypercholesterolemia ( P = 0.006) to be an independent risk factor for the development of intracranial aneurysms in blood group O and blood group A, respectively . Conclusion: Racial disparity in the distribution of blood groups and risk factor association with blood groups in the development of intracranial aneurysm needs to be considered. The findings from our study may be useful in identifying patients at increased risk of developing intracranial aneurysms.
ABO血型与颅内动脉瘤之间的关系尚不清楚。许多合并症因素与颅内动脉瘤有关。本文综述了颅内动脉瘤患者不同血型的患病率及其与危险因素的关系。方法:回顾性分析1993年1月1日至2012年12月31日在路易斯安那州立大学健康科学中心就诊并接受积极神经外科治疗的颅内动脉瘤患者。共有1248名患者被确定用于分析。有关这些患者的人口统计学和临床特征的数据由两位作者独立地从电子病历中提取。通过单因素和多因素分析，探讨ABO血型与颅内动脉瘤患者危险因素的关系。结果:研究人群中ABO血型最多的是O型(543例，43.5%)，其次是A型(525例，42%)。A血型(46% vs. 35.5%);P = 0.01)和B血型(18% vs 7%;P = 0.000)分别与白种人和非裔美国人颅内动脉瘤的发生显著相关。我们发现吸烟(P = 0.01)和高胆固醇血症(P = 0.006)分别是O型血和A型血颅内动脉瘤发生的独立危险因素。结论:颅内动脉瘤发生发展中，血型分布的种族差异及与血型相关的危险因素需要考虑。我们的研究结果可能有助于识别颅内动脉瘤风险增加的患者。
{"title":"Association of ABO blood groups with risk factors of intracranial cerebral aneurysm formation","authors":"S. Bir, P. Kalakoti, S. Ambekar, Papireddy Bollam, A. Nanda","doi":"10.4103/2230-7095.149764","DOIUrl":"https://doi.org/10.4103/2230-7095.149764","url":null,"abstract":"Introduction: The association between ABO blood groups and intracranial aneurysms is not well-understood. Many co-morbid factors are associated with intracranial aneurysms. The prevalence of different blood groups and associations with the risk factors in patients with intracranial aneurysms are reviewed. Methodology: A retrospective analysis was conducted on patients presenting with intracranial aneurysms and undergoing active neurosurgical intervention at the Louisiana State University Health Sciences Center between 1 st January 1993 and 31 st December 2012. A total of 1248 patients were identified for the analysis. Data pertaining to demographics and clinical characteristics of these patients were extracted from the electronic patient records by two authors independently. A univariate and multivariate analysis was performed to investigate the association of ABO blood groups with risk factors in patients with intracranial aneurysms. Results: The most common ABO blood group in our study population was O (543 cases, 43.5%), followed by group A (525 cases, 42%). Blood group A (46% vs. 35.5% patients; P = 0.01) and blood group B (18% vs. 7% patients; P = 0.000) were significantly associated with the development of intracranial aneurysms in Caucasians and African Americans, respectively. We found smoking ( P = 0.01) and hypercholesterolemia ( P = 0.006) to be an independent risk factor for the development of intracranial aneurysms in blood group O and blood group A, respectively . Conclusion: Racial disparity in the distribution of blood groups and risk factor association with blood groups in the development of intracranial aneurysm needs to be considered. The findings from our study may be useful in identifying patients at increased risk of developing intracranial aneurysms.","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125413217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-07-01DOI: 10.4103/2230-7095.149760
P. Subramanian
Idiopathic intracranial hypertension (IIH), also known as pseudotumor cerebri, may occur at any age but is primarily a disease of obese women between the ages of 15 and 40. Diagnosis is made based on modified Dandy criteria, which include normal neuroimaging studies, elevated intracranial pressure (ICP) on lumbar puncture, signs and symptoms of elevated ICP, and a non-focal neurologic examination aside from sixth nerve paresis. Presenting symptoms include headache, pulsatile tinnitus, transient visual obscurations, diplopia, and visual field constriction. Diagnosis may be delayed because headache from other causes such as migraine is much more common, and patients may be treated for this condition without improvement before the actual diagnosis is recognized. Ophthalmologic signs may include papilledema and esotropia (from the sixth nerve palsy) as well as visual field and even visual acuity loss; the latter two signs are very ominous, as they indicate severe and potentially permanent visual damage. Medical and surgical options vary depending on the severity of the disease and are used to control headache as well as to prevent vision loss. Because most IIH is associated with obesity, weight loss is an essential element of any treatment regimen, as retrospective as well as prospective studies have shown disease resolution with as little as 6% weight reduction. Secondary causes of high ICP are being recognized in a greater number of IIH patients, and the term idiopathic likely applies to fewer patients than in the past. The underlying pathogenesis of the disorder remains elusive.
{"title":"Idiopathic intracranial hypertension: diagnosis and management","authors":"P. Subramanian","doi":"10.4103/2230-7095.149760","DOIUrl":"https://doi.org/10.4103/2230-7095.149760","url":null,"abstract":"Idiopathic intracranial hypertension (IIH), also known as pseudotumor cerebri, may occur at any age but is primarily a disease of obese women between the ages of 15 and 40. Diagnosis is made based on modified Dandy criteria, which include normal neuroimaging studies, elevated intracranial pressure (ICP) on lumbar puncture, signs and symptoms of elevated ICP, and a non-focal neurologic examination aside from sixth nerve paresis. Presenting symptoms include headache, pulsatile tinnitus, transient visual obscurations, diplopia, and visual field constriction. Diagnosis may be delayed because headache from other causes such as migraine is much more common, and patients may be treated for this condition without improvement before the actual diagnosis is recognized. Ophthalmologic signs may include papilledema and esotropia (from the sixth nerve palsy) as well as visual field and even visual acuity loss; the latter two signs are very ominous, as they indicate severe and potentially permanent visual damage. Medical and surgical options vary depending on the severity of the disease and are used to control headache as well as to prevent vision loss. Because most IIH is associated with obesity, weight loss is an essential element of any treatment regimen, as retrospective as well as prospective studies have shown disease resolution with as little as 6% weight reduction. Secondary causes of high ICP are being recognized in a greater number of IIH patients, and the term idiopathic likely applies to fewer patients than in the past. The underlying pathogenesis of the disorder remains elusive.","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121366047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-01DOI: 10.4103/2230-7095.136494
T. Alshee, S. Shafi, M. Marwani, T. Khaled
We report a case of 46-year-old female patient who presented with a breast lump and was diagnosed as a case of idiopathic granulomatous mastitis. Patient was put on steroid therapy and her lesion completely disappeared, both clinically and radiologically. When we stopped the steroid therapy, the mass again recurred and patient had to undergo lumpectomy with no recurrence in follow-up of 1 year.
{"title":"A case of recurrent idiopathic granulomatous mastitis","authors":"T. Alshee, S. Shafi, M. Marwani, T. Khaled","doi":"10.4103/2230-7095.136494","DOIUrl":"https://doi.org/10.4103/2230-7095.136494","url":null,"abstract":"We report a case of 46-year-old female patient who presented with a breast lump and was diagnosed as a case of idiopathic granulomatous mastitis. Patient was put on steroid therapy and her lesion completely disappeared, both clinically and radiologically. When we stopped the steroid therapy, the mass again recurred and patient had to undergo lumpectomy with no recurrence in follow-up of 1 year.","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121569956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-01DOI: 10.4103/2230-7095.136504
F. Arshad, Yasin Ladakhi, M. Khan
{"title":"A rare case of carbamazepine induced pancreatitis","authors":"F. Arshad, Yasin Ladakhi, M. Khan","doi":"10.4103/2230-7095.136504","DOIUrl":"https://doi.org/10.4103/2230-7095.136504","url":null,"abstract":"","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127783865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-01DOI: 10.4103/2230-7095.136506
S. Dawn, A. Chaudhuri, Debashis Saha, Sumanta Ghosh Maulik
{"title":"Comparison between responses following use of fentanyl on heart rate and mean arterial pressure during endotracheal intubation and laryngeal mask airway insertion","authors":"S. Dawn, A. Chaudhuri, Debashis Saha, Sumanta Ghosh Maulik","doi":"10.4103/2230-7095.136506","DOIUrl":"https://doi.org/10.4103/2230-7095.136506","url":null,"abstract":"","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131316486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-01DOI: 10.4103/2230-7095.136496
H. Walia, R. Jain, Rekha Nirwan, R. Bansal, G. Gupta
Osteopetrosis is a group of rare genetic diseases, consequent on absent or defective osteoclasts. A large number of genes have been found to be associated with the defect, each of which results in a clinically variable phenotype with regards to age at presentation and severity of disease. This makes the disease a clinical diagnostic challenge. We present one such case which was diagnosed on trephine biopsy performed to understand the cause of the presence of blast cells in peripheral blood of an 8-month-old infant.
{"title":"Osteopetrosis: trephine biopsy an essential tool","authors":"H. Walia, R. Jain, Rekha Nirwan, R. Bansal, G. Gupta","doi":"10.4103/2230-7095.136496","DOIUrl":"https://doi.org/10.4103/2230-7095.136496","url":null,"abstract":"Osteopetrosis is a group of rare genetic diseases, consequent on absent or defective osteoclasts. A large number of genes have been found to be associated with the defect, each of which results in a clinically variable phenotype with regards to age at presentation and severity of disease. This makes the disease a clinical diagnostic challenge. We present one such case which was diagnosed on trephine biopsy performed to understand the cause of the presence of blast cells in peripheral blood of an 8-month-old infant.","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130617623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-01DOI: 10.4103/2230-7095.136497
P. Pamu, S. Yalavarthi, S. S. Kumar, Seetharamaiah
Gastrointestinal stromal tumors (GISTs) are tumors of mesenchymal origin arising from the walls of the gastrointestinal (GI) tract, with stomach being the most common site followed by the small intestine. Those with similar morphology identified outside the GI tract are termed extra-gastrointestinal stromal tumors and are often located in the mesentery, omentum, pelvis, retro-peritoneum, rectovaginal septum, perivaginal soft-tissue, and very rarely the prostate. Due to their malignant potential, it is utmost essential to diagnose such extra-intestinal occurrences, with immunochemistry being an effective tool in its diagnosis. We herein report a case of GIST of the prostrate in a 75-year-old male presenting with dysuria and urinary retention and discuss the role of immunohistochemistry markers that aid in diagnosis and its differentiation from other malignant conditions involving the prostrate. This case serves best to promote awareness of GIST in unusual anatomical locations to help early diagnosis and prompt subsequent management.
{"title":"Extra-gastrointestinal stromal tumor arising in the prostate: an unusual anatomical location","authors":"P. Pamu, S. Yalavarthi, S. S. Kumar, Seetharamaiah","doi":"10.4103/2230-7095.136497","DOIUrl":"https://doi.org/10.4103/2230-7095.136497","url":null,"abstract":"Gastrointestinal stromal tumors (GISTs) are tumors of mesenchymal origin arising from the walls of the gastrointestinal (GI) tract, with stomach being the most common site followed by the small intestine. Those with similar morphology identified outside the GI tract are termed extra-gastrointestinal stromal tumors and are often located in the mesentery, omentum, pelvis, retro-peritoneum, rectovaginal septum, perivaginal soft-tissue, and very rarely the prostate. Due to their malignant potential, it is utmost essential to diagnose such extra-intestinal occurrences, with immunochemistry being an effective tool in its diagnosis. We herein report a case of GIST of the prostrate in a 75-year-old male presenting with dysuria and urinary retention and discuss the role of immunohistochemistry markers that aid in diagnosis and its differentiation from other malignant conditions involving the prostrate. This case serves best to promote awareness of GIST in unusual anatomical locations to help early diagnosis and prompt subsequent management.","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123899181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-01DOI: 10.4103/2230-7095.136505
T. Lemon, A. C. Lee
{"title":"Estrogen's protective affect for gastric cancer?","authors":"T. Lemon, A. C. Lee","doi":"10.4103/2230-7095.136505","DOIUrl":"https://doi.org/10.4103/2230-7095.136505","url":null,"abstract":"","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127569794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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