Pub Date : 1900-01-01DOI: 10.4103/2230-7095.113487
S. Nigwekar, A. Gupta, Megha Bhosale, Tanvi Haldipurkar, B. Baviskar, S. Misra
Squamous cell carcinoma is an invasive type of ocular surface squamous neoplasia which is a term introduced for premalignant and malignant epithelial lesions from conjunctiva and cornea. Treatment outcome of ocular surface squamous neoplasia (OSSN) depends on its type and stage, which is confirmed by histopathological examination. Invasive type of OSSN as squamous cell carcinoma needs combined treatment to reduce its recurrence. We present a case of a 45 year old female patient with positive HIV status, presenting to our outpatient clinic with a progressive limbal mass. She underwent combined treatment modality with total excision along with cryo-application and topical mitomycin-C drops with no evidence of recurrence on follow-up for a year. Emphasis on various adjunctive therapies along with the surgical approach is also discussed.
{"title":"Combined treatment modality for invasive ocular surface squamous neoplasia in an HIV positive patient: a case report","authors":"S. Nigwekar, A. Gupta, Megha Bhosale, Tanvi Haldipurkar, B. Baviskar, S. Misra","doi":"10.4103/2230-7095.113487","DOIUrl":"https://doi.org/10.4103/2230-7095.113487","url":null,"abstract":"Squamous cell carcinoma is an invasive type of ocular surface squamous neoplasia which is a term introduced for premalignant and malignant epithelial lesions from conjunctiva and cornea. Treatment outcome of ocular surface squamous neoplasia (OSSN) depends on its type and stage, which is confirmed by histopathological examination. Invasive type of OSSN as squamous cell carcinoma needs combined treatment to reduce its recurrence. We present a case of a 45 year old female patient with positive HIV status, presenting to our outpatient clinic with a progressive limbal mass. She underwent combined treatment modality with total excision along with cryo-application and topical mitomycin-C drops with no evidence of recurrence on follow-up for a year. Emphasis on various adjunctive therapies along with the surgical approach is also discussed.","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115155336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4103/2230-7095.180082
Minakshi R Hivarkar, H. Umarji, Sonali G. Kadam, K. Kumar
Diffuse large B-cell lymphoma is a Non-Hodgkin's lymphoma (NHL), which has diverse manifestations. Extra-nodal NHL is extremely rare entity. Diagnosis, staging and treatment plan of the patient depends on the clinical findings and radiographic investigations. Positron emission tomography computed tomography (PET CT) scan helps in localization of the lesion and also for posttreatment restaging. Here we are presenting a case report of a 21-year-old patient with diffuse large B-cell lymphoma. This case report highlights the importance of imaging for localization of the lesion and posttreatment evaluation of the lesion.
{"title":"Radiographic pattern of extra-nodal non-Hodgkin's lymphoma","authors":"Minakshi R Hivarkar, H. Umarji, Sonali G. Kadam, K. Kumar","doi":"10.4103/2230-7095.180082","DOIUrl":"https://doi.org/10.4103/2230-7095.180082","url":null,"abstract":"Diffuse large B-cell lymphoma is a Non-Hodgkin's lymphoma (NHL), which has diverse manifestations. Extra-nodal NHL is extremely rare entity. Diagnosis, staging and treatment plan of the patient depends on the clinical findings and radiographic investigations. Positron emission tomography computed tomography (PET CT) scan helps in localization of the lesion and also for posttreatment restaging. Here we are presenting a case report of a 21-year-old patient with diffuse large B-cell lymphoma. This case report highlights the importance of imaging for localization of the lesion and posttreatment evaluation of the lesion.","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128376166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4103/2230-7095.113494
Mikalai Luhautsou, Andrei Platonau, Andrei Beloveshkin
{"title":"Localization of S-100 and CD1a positive dendritic cells in the human thymus","authors":"Mikalai Luhautsou, Andrei Platonau, Andrei Beloveshkin","doi":"10.4103/2230-7095.113494","DOIUrl":"https://doi.org/10.4103/2230-7095.113494","url":null,"abstract":"","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132827923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4103/2230-7095.113821
S. S. Shastry
Inflammatory myofibroblastic tumor (IMT) of the liver is a rare tumor like lesion that can mimic malignant liver neoplasm. IMT is a lesion composed of myofibroblastic spindle cells, plasma cells, lymphocytes, and eosinophils. It can occur in soft tissues and viscera. It was previously called plasma cell granuloma, inflammatory myofibrohistiocytic proliferation, and inflammatory pseudo tumor, but IMT is the designation currently used. IMT is more frequently described in the lung and abdomen of young patients, but it can also be found in the central nervous system, salivary glands, larynx, bladder, breast, spleen, skin, and liver. Here, we present a case of IMT of the liver in a 55-year-old female patient which is a rare presentation.
{"title":"Inflammatory myofibroblastic tumor of the liver: A rare pathological entity","authors":"S. S. Shastry","doi":"10.4103/2230-7095.113821","DOIUrl":"https://doi.org/10.4103/2230-7095.113821","url":null,"abstract":"Inflammatory myofibroblastic tumor (IMT) of the liver is a rare tumor like lesion that can mimic malignant liver neoplasm. IMT is a lesion composed of myofibroblastic spindle cells, plasma cells, lymphocytes, and eosinophils. It can occur in soft tissues and viscera. It was previously called plasma cell granuloma, inflammatory myofibrohistiocytic proliferation, and inflammatory pseudo tumor, but IMT is the designation currently used. IMT is more frequently described in the lung and abdomen of young patients, but it can also be found in the central nervous system, salivary glands, larynx, bladder, breast, spleen, skin, and liver. Here, we present a case of IMT of the liver in a 55-year-old female patient which is a rare presentation.","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"22 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116686691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4103/IJSR.INT_J_STUD_RES_8_17
M. Syed
{"title":"Violence against healthcare professionals: are we looking for the peaceful truce?","authors":"M. Syed","doi":"10.4103/IJSR.INT_J_STUD_RES_8_17","DOIUrl":"https://doi.org/10.4103/IJSR.INT_J_STUD_RES_8_17","url":null,"abstract":"","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126058999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4103/2230-7095.113479
P. Kalakoti, M. Aarif, P. Thacker, S. Veeranki
{"title":"International Journal of Students' Research: making strides forward","authors":"P. Kalakoti, M. Aarif, P. Thacker, S. Veeranki","doi":"10.4103/2230-7095.113479","DOIUrl":"https://doi.org/10.4103/2230-7095.113479","url":null,"abstract":"","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127399985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4103/2230-7095.180086
Garima Singh, A. Thakur, H. Sadiq, Priti Gupta
Central Giant Cell Granuloma (CGCG) was differentiated from Giant Cell Tumor of bone by Jaffe in 1953. Various authors have advocated this intraosseous lesion as a reactive lesion or developmental anomaly or a benign neoplasm. Actual etiology is not comprehensible till date and it has also been hypothesized to have a genetic etiology. Lesions are most commonly found in mandible but frequently crossing the midline. However, variable clinical features and radiological changes have been demonstrated by giant cell lesions of the jaws. In this case report, a young female patient reported with the chief complaint of swelling in right mandibular posterior tooth region since 2 wks after dental extraction from the same region. The patient underwent the treatment as surgical curettage followed by removal of the lesion and subsequent histopathological examination which confirmed the diagnosis of CGCG. There was no recurrence reported in 10 months of follow up.
{"title":"Central giant cell granuloma: A case report with diagnostic dilemma","authors":"Garima Singh, A. Thakur, H. Sadiq, Priti Gupta","doi":"10.4103/2230-7095.180086","DOIUrl":"https://doi.org/10.4103/2230-7095.180086","url":null,"abstract":"Central Giant Cell Granuloma (CGCG) was differentiated from Giant Cell Tumor of bone by Jaffe in 1953. Various authors have advocated this intraosseous lesion as a reactive lesion or developmental anomaly or a benign neoplasm. Actual etiology is not comprehensible till date and it has also been hypothesized to have a genetic etiology. Lesions are most commonly found in mandible but frequently crossing the midline. However, variable clinical features and radiological changes have been demonstrated by giant cell lesions of the jaws. In this case report, a young female patient reported with the chief complaint of swelling in right mandibular posterior tooth region since 2 wks after dental extraction from the same region. The patient underwent the treatment as surgical curettage followed by removal of the lesion and subsequent histopathological examination which confirmed the diagnosis of CGCG. There was no recurrence reported in 10 months of follow up.","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"04 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129973302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4103/2230-7095.113481
I. Christakis, Ilias-Dimitrios Kafetzis, A. Diamantopoulos, V. Leoutsakos
In the early decades of the 20th century it was established that some non neuro-endocrine malignant tumors and their metastasis, were secreting substances with biologic properties and causing clinical syndromes similar to the ones caused by naturally occurring hormones. The most known syndromes are caused by substances mimicking the biologic properties of ACTH, erythropoietin, insulin and PTH. Many theories have been postulated in an attempt to explain the synthesis process of hormone mimetic substances. Ectopic secretion of ACTH syndrome comprises 10%-20% of all cases presenting with Cushing's syndrome. The clinical picture manifests in a variable way. The increased plasma levels of cortisol in these cases, cause symptoms distinct from the ones of true Cushing's syndrome. In general these patients have an ominous prognosis. Survival is limited to 6-12 months and is attributed to hypercortisolemia that is known to increase the risk of metastasis. Hypercalcemia syndrome from ectopic secretion of hypercalcemic factors is a severe complication of cancer patients with an incidence of 5-10%. Increased serum calcium is caused either by the osteolytic metastasis of malignant tumors or by their secretions. The clinical picture caused is similar to the findings of primary hyperparathyroidism. Treatment options in case of acute and severe hypercalcemia in patients with malignancy are limited. The endocrine syndromes produced by non-endocrine tumors not only affect patient's quality of life but also occasionally cause severe complications and can disrupt surgical or medical treatment of the primary tumor. Searching for the occurrence of such syndromes demands a high index of suspicion. This paper brings the spotlight back to the clinical syndromes of hypercortisolemia and hypercalcemia caused by ectopic ACTH and hypercalcemic factors respectively, re-iterating the need for early diagnosis and prompt management in such cases.
{"title":"Non-endocrine tumors causing endocrine syndromes: a brief review","authors":"I. Christakis, Ilias-Dimitrios Kafetzis, A. Diamantopoulos, V. Leoutsakos","doi":"10.4103/2230-7095.113481","DOIUrl":"https://doi.org/10.4103/2230-7095.113481","url":null,"abstract":"In the early decades of the 20th century it was established that some non neuro-endocrine malignant tumors and their metastasis, were secreting substances with biologic properties and causing clinical syndromes similar to the ones caused by naturally occurring hormones. The most known syndromes are caused by substances mimicking the biologic properties of ACTH, erythropoietin, insulin and PTH. Many theories have been postulated in an attempt to explain the synthesis process of hormone mimetic substances. Ectopic secretion of ACTH syndrome comprises 10%-20% of all cases presenting with Cushing's syndrome. The clinical picture manifests in a variable way. The increased plasma levels of cortisol in these cases, cause symptoms distinct from the ones of true Cushing's syndrome. In general these patients have an ominous prognosis. Survival is limited to 6-12 months and is attributed to hypercortisolemia that is known to increase the risk of metastasis. Hypercalcemia syndrome from ectopic secretion of hypercalcemic factors is a severe complication of cancer patients with an incidence of 5-10%. Increased serum calcium is caused either by the osteolytic metastasis of malignant tumors or by their secretions. The clinical picture caused is similar to the findings of primary hyperparathyroidism. Treatment options in case of acute and severe hypercalcemia in patients with malignancy are limited. The endocrine syndromes produced by non-endocrine tumors not only affect patient's quality of life but also occasionally cause severe complications and can disrupt surgical or medical treatment of the primary tumor. Searching for the occurrence of such syndromes demands a high index of suspicion. This paper brings the spotlight back to the clinical syndromes of hypercortisolemia and hypercalcemia caused by ectopic ACTH and hypercalcemic factors respectively, re-iterating the need for early diagnosis and prompt management in such cases.","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"40 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120972320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.4103/2230-7095.180090
A. Jena, R. Patnayak, G. Reddy
{"title":"Doctor-patient relationship: Great expectations","authors":"A. Jena, R. Patnayak, G. Reddy","doi":"10.4103/2230-7095.180090","DOIUrl":"https://doi.org/10.4103/2230-7095.180090","url":null,"abstract":"","PeriodicalId":299761,"journal":{"name":"International journal of students' research","volume":"149 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122454301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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