F. JennyCarolinaSalazar, R. DiegoAlejandroRangel, R. NéstorEduardoOspino, J. Quirós
{"title":"Fístulas coronario-pulmonares asintomáticas. Reporte caso","authors":"F. JennyCarolinaSalazar, R. DiegoAlejandroRangel, R. NéstorEduardoOspino, J. Quirós","doi":"10.26445/05.03.3","DOIUrl":"https://doi.org/10.26445/05.03.3","url":null,"abstract":"","PeriodicalId":30552,"journal":{"name":"Innotec","volume":"5 1","pages":"19-25"},"PeriodicalIF":0.0,"publicationDate":"2020-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46777013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Systemic Autoimmune Diseases are a group of low-prevalence diseases whose pathogeny is based on the loss of self-tolerance. Despite their low incidence and prevalence, deepening the study and knowledge of these diseases has enabled significant diagnostic and therapeutic advances in recent years, constituting a challenge in clinical practice. Objective: to determine the prevalence and clinical-humoral characteristics of these pathologies in the Polyclinic of Autoimmune Diseases of Pasteur Hospital, in the period 2016 -2019. Results: The total population was 62 patients., 55/62 (88%) were women. Most prevalent was Systemic Lupus Erythematosus (SLE), representing 32% of this population (20/62), Rheumatoid Arthritis by 21% (13/62), Systemic Sclerosis by 8% (5/62), Systemic vasculitis 8% (5/62), Overlap syndrome 6% (4/62), Bechet 5% (3/62). Conclusions: Lupus and rheumatoid arthritis as more prevalent diseases, as well as a maintained increase in other less common diseases. It is very important to promote the development of specialized units in these área, in order to improve and protocol the management of these patients.
{"title":"Unidad de enfermedades autoinmunes: experiencia de un centro","authors":"Mariana Cruz, Diego Graña, J. Gaudiano, L. Pérez","doi":"10.26445/05.02.4","DOIUrl":"https://doi.org/10.26445/05.02.4","url":null,"abstract":"Introduction: Systemic Autoimmune Diseases are a group of low-prevalence diseases whose pathogeny is based on the loss of self-tolerance. Despite their low incidence and prevalence, deepening the study and knowledge of these diseases has enabled significant diagnostic and therapeutic advances in recent years, constituting a challenge in clinical practice. Objective: to determine the prevalence and clinical-humoral characteristics of these pathologies in the Polyclinic of Autoimmune Diseases of Pasteur Hospital, in the period 2016 -2019. Results: The total population was 62 patients., 55/62 (88%) were women. Most prevalent was Systemic Lupus Erythematosus (SLE), representing 32% of this population (20/62), Rheumatoid Arthritis by 21% (13/62), Systemic Sclerosis by 8% (5/62), Systemic vasculitis 8% (5/62), Overlap syndrome 6% (4/62), Bechet 5% (3/62). Conclusions: Lupus and rheumatoid arthritis as more prevalent diseases, as well as a maintained increase in other less common diseases. It is very important to promote the development of specialized units in these área, in order to improve and protocol the management of these patients.","PeriodicalId":30552,"journal":{"name":"Innotec","volume":"5 1","pages":"28-36"},"PeriodicalIF":0.0,"publicationDate":"2020-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44549039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Miocardiopatía por Influenza A H1N1. Reporte de un caso clínico","authors":"Sofía Rostán, Natasha Smiliansky, Andrea Vaucher","doi":"10.26445/05.03.4","DOIUrl":"https://doi.org/10.26445/05.03.4","url":null,"abstract":"","PeriodicalId":30552,"journal":{"name":"Innotec","volume":"5 1","pages":"26-30"},"PeriodicalIF":0.0,"publicationDate":"2020-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49191196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lorena Bruno, M. Garau, Lorena Barreneche, Laura Ureta, Santiago Algorta, Roberto Di Lorenzi, Eugenia Ruiz Díaz, Iris Melone
{"title":"Control glicémico del paciente quirúrgico","authors":"Lorena Bruno, M. Garau, Lorena Barreneche, Laura Ureta, Santiago Algorta, Roberto Di Lorenzi, Eugenia Ruiz Díaz, Iris Melone","doi":"10.26445/05.03.2","DOIUrl":"https://doi.org/10.26445/05.03.2","url":null,"abstract":"","PeriodicalId":30552,"journal":{"name":"Innotec","volume":"5 1","pages":"14-18"},"PeriodicalIF":0.0,"publicationDate":"2020-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47358610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seasonal variations and interannual changes (2006-2019) of the phytoplankton community, related to variations in water quality and river discharge, in the lower part of the Uruguay River in South America are presented. In total, 422 microalgae and cyanobacterial taxa were identified. Cryptophytes, cyanobacteria, and diatoms were the most important groups. Although nanoflagellates and cryptophytes were always present in plankton, statistical differences were found in seasonal assemblages of phytoplankton. According to the similarity analysis (SIMPER), the typical species for each season were identified: Aulacoseira spp. in winter, Dolichospermum uruguayense, Durinskia baltica and Ankistrodesmus arcuatus in spring, Microcystis aeruginosa, M. wesenbergii, Dolichospermum uruguayense and D. circinale in summer and Ceratium cf. furcoides, A. arcuatus, Raphidiopsis and Jaaginema sp. in autumn. Under lentic river conditions (<2000 m3 s-1) and above 22oC, high biomass was recorded due to the blooms of Microcystis and Dolichospermum. In 2010, M. panniformis reached 10.4 µg l-1 microcystin-LR. Raphidiopsis mediterranea and R. raciborskii began to be registered in Spring (2009 and 2014 respectively) reaching 1041 cell ml-1 in Spring 2017. This paper shows that flow, transparency and temperature are the main factors that regulate phytoplankton biomass and cyanobacterial blooms in the Uruguay River. In the summer, when the Uruguay River is in low flow conditions, cyanobacteria remain in the river. When flow increases, cyanobacteria are transported downstream and could reach the estuary of the Rio de la Plata, impacting its beaches.
{"title":"Water flow and temperature as main factors that regulate phytoplankton and cyanobacterial blooms in a large subtropical river","authors":"Graciela Ferrari","doi":"10.26461/20.07","DOIUrl":"https://doi.org/10.26461/20.07","url":null,"abstract":"Seasonal variations and interannual changes (2006-2019) of the phytoplankton community, related to variations in water quality and river discharge, in the lower part of the Uruguay River in South America are presented. In total, 422 microalgae and cyanobacterial taxa were identified. Cryptophytes, cyanobacteria, and diatoms were the most important groups. Although nanoflagellates and cryptophytes were always present in plankton, statistical differences were found in seasonal assemblages of phytoplankton. According to the similarity analysis (SIMPER), the typical species for each season were identified: Aulacoseira spp. in winter, Dolichospermum uruguayense, Durinskia baltica and Ankistrodesmus arcuatus in spring, Microcystis aeruginosa, M. wesenbergii, Dolichospermum uruguayense and D. circinale in summer and Ceratium cf. furcoides, A. arcuatus, Raphidiopsis and Jaaginema sp. in autumn. Under lentic river conditions (<2000 m3 s-1) and above 22oC, high biomass was recorded due to the blooms of Microcystis and Dolichospermum. In 2010, M. panniformis reached 10.4 µg l-1 microcystin-LR. Raphidiopsis mediterranea and R. raciborskii began to be registered in Spring (2009 and 2014 respectively) reaching 1041 cell ml-1 in Spring 2017. This paper shows that flow, transparency and temperature are the main factors that regulate phytoplankton biomass and cyanobacterial blooms in the Uruguay River. In the summer, when the Uruguay River is in low flow conditions, cyanobacteria remain in the river. When flow increases, cyanobacteria are transported downstream and could reach the estuary of the Rio de la Plata, impacting its beaches.","PeriodicalId":30552,"journal":{"name":"Innotec","volume":"1 1","pages":"30-66"},"PeriodicalIF":0.0,"publicationDate":"2020-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46982272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fabiana Rey Bentos, Fabián Marcel Capdevielle Sosa
The market for botanical products is growing worldwide due to consumers preference for natural products. This makes them targets for adulteration, which is more common and difficult to detect in industrialized derivatives. It is critical to have reliable procedures that allow their authentication. In this study, DNA-based molecular tools were applied to generate applied genomic information to classify samples of fresh and industrialized aromatic and medicinal herbs. The work was based on the DNA Barcoding strategy using fresh tissue samples of known taxonomic identity (references) and industrialized samples. The results obtained indicate that the rbcL and matK markers are amplifiable with the primers used, obtaining high quality bi-directional sequences in the case of fresh tissue in 83% of the cases for rbcL and in 63% of the cases for matK. In the industrialized samples the values were 50 and 35% respectively. The BOLD tool allowed the classification of most of the samples. This methodology is a useful and accessible tool that allows the classification in groups, although its performance is limited by the representation of the species in the databases.
{"title":"Aplicación del Código de Barras de ADN (DNA Barcoding) para la identificación de especies vegetales de interés industrial","authors":"Fabiana Rey Bentos, Fabián Marcel Capdevielle Sosa","doi":"10.26461/20.06","DOIUrl":"https://doi.org/10.26461/20.06","url":null,"abstract":"The market for botanical products is growing worldwide due to consumers preference for natural products. This makes them targets for adulteration, which is more common and difficult to detect in industrialized derivatives. It is critical to have reliable procedures that allow their authentication. In this study, DNA-based molecular tools were applied to generate applied genomic information to classify samples of fresh and industrialized aromatic and medicinal herbs. The work was based on the DNA Barcoding strategy using fresh tissue samples of known taxonomic identity (references) and industrialized samples. The results obtained indicate that the rbcL and matK markers are amplifiable with the primers used, obtaining high quality bi-directional sequences in the case of fresh tissue in 83% of the cases for rbcL and in 63% of the cases for matK. In the industrialized samples the values were 50 and 35% respectively. The BOLD tool allowed the classification of most of the samples. This methodology is a useful and accessible tool that allows the classification in groups, although its performance is limited by the representation of the species in the databases.","PeriodicalId":30552,"journal":{"name":"Innotec","volume":"1 1","pages":"117-138"},"PeriodicalIF":0.0,"publicationDate":"2020-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47390223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Geochronology constitutes a fundamental tool for the study of historical events. Its development in Uruguay has been closely linked with archaeological studies. In the last 20 years, dating techniques have expanded into other disciplines, leading to methodological changes and improvements. The most widely used method to study the chronology of most recent Holocene climatic and environmental events is 210Pb-137Cs. The objective of this manuscript is the development in Uruguay of the 210Pb-137Cs geochronological method and its application to a study case. For this, a vertical sediment core was taken from Laguna de las Nutrias (Rocha), which was sub-sampled, and the sections were measured by gamma spectrometry, determining the 210Pb, 226Ra and 137Cs radionuclides. The 210Pb concentration was mathematically modeled, finding that the best fit model is the constant rate of supply model. This model was positively corroborated against the historical profile of 137Cs activity from nuclear events. The annual sedimentation rate was calculated to be 3.1 ± 1.5 mm/year-1 from 1870 to 1986 AD and 4.7 ± 0.8 mm.year-1 after 1986 AD. Likewise, an extreme event possibly associated to the inherent climatic variability of Little Ice Age was inferred.
地质年代学是研究历史事件的基本工具。它在乌拉圭的发展与考古研究密切相关。在过去的20年里，测年技术已经扩展到其他学科，导致了方法的改变和改进。研究最近全新世气候和环境事件年表最广泛使用的方法是210Pb-137Cs。本文的目的是介绍210Pb-137Cs地质年代学方法在乌拉圭的发展及其在一个研究案例中的应用。为此，从Laguna de las Nutrias（Rocha）采集了一个垂直沉积物岩心，对其进行了亚采样，并通过伽马光谱法测量了剖面，确定了210Pb、226Ra和137Cs放射性核素。对210Pb浓度进行了数学建模，发现最适合的模型是恒定供应率模型。这一模型与核事件中137Cs活动的历史概况得到了积极的证实。经计算，公元1870年至1986年的年沉降率为3.1±1.5 mm/年-1，1986年后为4.7±0.8 mm/年-年-1。同样，推断出可能与小冰期固有气候变化有关的极端事件。
{"title":"Implementación de la datación mediante 210Pb - 137Cs en Uruguay para el reconocimiento de la variabilidad climático-ambiental del Holoceno superior. Caso de estudio: Laguna de las Nutrias - Rocha - Uruguay","authors":"Germán Azcune, A. Parada, Laura Fornaro","doi":"10.26461/20.04","DOIUrl":"https://doi.org/10.26461/20.04","url":null,"abstract":"Geochronology constitutes a fundamental tool for the study of historical events. Its development in Uruguay has been closely linked with archaeological studies. In the last 20 years, dating techniques have expanded into other disciplines, leading to methodological changes and improvements. The most widely used method to study the chronology of most recent Holocene climatic and environmental events is 210Pb-137Cs. The objective of this manuscript is the development in Uruguay of the 210Pb-137Cs geochronological method and its application to a study case. For this, a vertical sediment core was taken from Laguna de las Nutrias (Rocha), which was sub-sampled, and the sections were measured by gamma spectrometry, determining the 210Pb, 226Ra and 137Cs radionuclides. The 210Pb concentration was mathematically modeled, finding that the best fit model is the constant rate of supply model. This model was positively corroborated against the historical profile of 137Cs activity from nuclear events. The annual sedimentation rate was calculated to be 3.1 ± 1.5 mm/year-1 from 1870 to 1986 AD and 4.7 ± 0.8 mm.year-1 after 1986 AD. Likewise, an extreme event possibly associated to the inherent climatic variability of Little Ice Age was inferred.","PeriodicalId":30552,"journal":{"name":"Innotec","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47014669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hugo I. Coitiño, Agustina Serrón Lacassie, Agustina Serrón
{"title":"Atropellos de mamíferos en la Región Este de Uruguay y su relación con atributos del paisaje","authors":"Hugo I. Coitiño, Agustina Serrón Lacassie, Agustina Serrón","doi":"10.26461/20.05","DOIUrl":"https://doi.org/10.26461/20.05","url":null,"abstract":"","PeriodicalId":30552,"journal":{"name":"Innotec","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45905367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A set of data collected during 2016 was studied in eight wells in the city of Maturin, Monagas, Venezuela, in an attempt to evaluate and determine the contributions of the source that affect water quality. An accurate multiple linear regression (MRL) technique was used as an advanced tool for modeling and forecasting groundwater quality. Likewise, principal component analysis (PCA) was used to simplify and understand the complex relationship between water and quality parameters. Six main components responsible for 86.57% of the total variation were found. It was found that the main source of contamination of Maturin aquifers was the residual discharges with high values of fecal coliforms. An advanced receiver model was applied in order to identify the main sources of contamination. The result showed that the use of PCA as inputs improved the prediction of the MRL model by reducing its complexity and eliminating the collinearity of data, where the value of R2 in this study was 0.99, indicating that 99% of the variability of the water quality index (WQI) is explained by the eleven independent variables used in the model.
{"title":"Groundwater quality model through the combined use of principal component analysis (PCA) and multiple linear regression (MLR) Case study: Maturín’s aquifers, Monagas, Venezuela","authors":"","doi":"10.26461/20.02","DOIUrl":"https://doi.org/10.26461/20.02","url":null,"abstract":"A set of data collected during 2016 was studied in eight wells in the city of Maturin, Monagas, Venezuela, in an attempt to evaluate and determine the contributions of the source that affect water quality. An accurate multiple linear regression (MRL) technique was used as an advanced tool for modeling and forecasting groundwater quality. Likewise, principal component analysis (PCA) was used to simplify and understand the complex relationship between water and quality parameters. Six main components responsible for 86.57% of the total variation were found. It was found that the main source of contamination of Maturin aquifers was the residual discharges with high values of fecal coliforms. An advanced receiver model was applied in order to identify the main sources of contamination. The result showed that the use of PCA as inputs improved the prediction of the MRL model by reducing its complexity and eliminating the collinearity of data, where the value of R2 in this study was 0.99, indicating that 99% of the variability of the water quality index (WQI) is explained by the eleven independent variables used in the model.","PeriodicalId":30552,"journal":{"name":"Innotec","volume":"14 9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69329288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalia Badagian Baharian, M. Letamendía, M. Pirez, D. Carnevia, Beatriz M. Brena
The high incidence of cyanobacterial blooms producing microcystins in Uruguay and its region, represent a very high risk for humans and animals. To study the impact and the presence of microcystins (MCs) in animals, it is important to use simple, low-cost methods. As a first approach to these objectives in fish, a sub-chronic bioassay (18 days) was performed with Astraloheros facetus (Castanetas) exposed to a Microcystis spp, bloom containing MCs (60 and 600 µg MCs/L). Even though there was no mortality, the histopathology showed fatty infiltration of the liver, which was more relevant in fish exposed to the highest concentration. To analyze MCs in tissues, two sensitive immunochemical methods based on a highly specific recombinant llama antibody (nanobody) were optimized: ELISA and quantitative MALDI-TOF, using functionalized magnetic particles. The methods were recently developed locally. The excellent correlation ELISA/MALDI-TOF (r Spearman = 0.988, p <10-7), highlights the potential of this ELISA as a simple and cost-effective tool to minimize the samples to be analyzed by reference methods. The concentrations of MCs in tissue of Astraloheros facetus were relevant, consistent with bioassays in other species and fish from nature. This highlights the importance of analyzing MCs in fish for consumption.
{"title":"Nuevas metodologías para el análisis de microcistinas en peces. Estudio de Astraloheros Facetus expuestos in vitro.","authors":"Natalia Badagian Baharian, M. Letamendía, M. Pirez, D. Carnevia, Beatriz M. Brena","doi":"10.26461/20.03","DOIUrl":"https://doi.org/10.26461/20.03","url":null,"abstract":"The high incidence of cyanobacterial blooms producing microcystins in Uruguay and its region, represent a very high risk for humans and animals. To study the impact and the presence of microcystins (MCs) in animals, it is important to use simple, low-cost methods. As a first approach to these objectives in fish, a sub-chronic bioassay (18 days) was performed with Astraloheros facetus (Castanetas) exposed to a Microcystis spp, bloom containing MCs (60 and 600 µg MCs/L). Even though there was no mortality, the histopathology showed fatty infiltration of the liver, which was more relevant in fish exposed to the highest concentration. To analyze MCs in tissues, two sensitive immunochemical methods based on a highly specific recombinant llama antibody (nanobody) were optimized: ELISA and quantitative MALDI-TOF, using functionalized magnetic particles. The methods were recently developed locally. The excellent correlation ELISA/MALDI-TOF (r Spearman = 0.988, p <10-7), highlights the potential of this ELISA as a simple and cost-effective tool to minimize the samples to be analyzed by reference methods. The concentrations of MCs in tissue of Astraloheros facetus were relevant, consistent with bioassays in other species and fish from nature. This highlights the importance of analyzing MCs in fish for consumption.","PeriodicalId":30552,"journal":{"name":"Innotec","volume":"1 1","pages":"10-29"},"PeriodicalIF":0.0,"publicationDate":"2020-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43820334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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