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The comparison of cardiovascular risk scores using two methods of substituting missing risk factor data in patient medical records. 用两种方法替代患者病历中缺失的危险因素数据对心血管危险评分的比较
Pub Date : 2011-01-01 DOI: 10.14236/jhi.v19i4.817
Andrew R H Dalton, Alex Bottle, Michael Soljak, Cyprian Okoro, Azeem Majeed, Christopher Millett
BACKGROUNDTargeted screening for cardiovascular disease (CVD) can be carried out using existing data from patient medical records. However, electronic medical records in UK general practice contain missing risk factor data for which values must be estimated to produce risk scores.OBJECTIVETo compare two methods of substituting missing risk factor data; multiple imputation and the use of default National Health Survey values.METHODSWe took patient-level data from patients in 70 general practices in Ealing, North West London. We substituted missing risk factor data using the two methods, applied two risk scores (QRISK2 and JBS2) to the data and assessed differences between methods.RESULTSUsing multiple imputation, mean CVD risk scores were similar to those using default national survey values, a simple method of imputation. There were fewer patients designated as high risk (>20%) using multiple imputation, although differences were again small (10.3% compared with 11.7%; 3.0% compared with 3.4% in women). Agreement in high-risk classification between methods was high (Kappa = 0.91 in men; 0.90 in women).CONCLUSIONSA simple method of substituting missing risk factor data can produce reliable estimates of CVD risk scores. Targeted screening for high CVD risk, using pre-existing electronic medical record data, does not require multiple imputation methods in risk estimation.
背景:心血管疾病(CVD)的靶向筛查可以利用现有的患者病历数据进行。然而,英国全科医疗的电子病历包含缺失的风险因素数据,必须对其值进行估计才能产生风险评分。目的:比较两种替代缺失危险因素数据的方法;多重代入和使用默认的国民健康调查值。方法:我们从伦敦西北部伊灵70家全科诊所的患者中获取患者水平的数据。我们使用两种方法替换缺失的风险因素数据,对数据应用两种风险评分(QRISK2和JBS2)并评估方法之间的差异。结果:使用多重imputation,平均心血管疾病风险评分与使用默认的国家调查值相似,这是一种简单的方法。使用多重植入的高危患者较少(>20%),尽管差异也很小(10.3%比11.7%;3.0%,而女性为3.4%)。两种方法在高危分类上的一致性很高(男性Kappa = 0.91;女性0.90)。结论:一种简单的方法替代缺失的危险因素数据可以产生可靠的CVD风险评分。利用已有的电子病历数据,对心血管疾病高危人群进行针对性筛查,在风险评估中不需要多种方法。
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引用次数: 8
Understanding end-user support for health information technology: a theoretical framework. 理解终端用户对卫生信息技术的支持:一个理论框架。
Pub Date : 2011-01-01 DOI: 10.14236/jhi.v19i3.810
Aviv Shachak, Jan Barnsley, Karen Tu, Alejandro R Jadad, Louise Lemieux-Charles

Background: Support is often considered an important factor for successful implementation and realising the benefits of health information technology (HIT); however, there is a dearth of research on support and theoretical frameworks to characterise it.

Objective: To develop and present a comprehensive, holistic, framework for characterising enduser support that can be applied to various settings and types of information systems.

Method: Scoping review of the medical informatics and information systems literature.

Results: A theoretical framework of end-user support is presented. It includes the following facets: support source, location of support, support activities, and perceived characteristics of support and support personnel.

Conclusion: The proposed framework may be a useful tool for describing and characterising enduser support for HIT. it may also be used by decision makers and implementation leaders for planning purposes.

背景:支持通常被认为是成功实施和实现卫生信息技术(HIT)效益的重要因素;然而,缺乏对其特征的支持和理论框架的研究。目标:开发并呈现一个全面的、整体的框架,用于描述可应用于各种设置和类型的信息系统的最终用户支持。方法:对医学信息学与信息系统相关文献进行综述。结果:提出了终端用户支持的理论框架。它包括以下几个方面:支持来源、支持地点、支持活动、支持和支持人员的感知特征。结论:提出的框架可能是描述和表征终端用户对HIT的支持的有用工具。它也可以被决策者和执行领导者用于规划目的。
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引用次数: 15
The history of the Read Codes: the inaugural James Read Memorial Lecture 2011. 里德密码的历史:2011年詹姆斯·里德纪念讲座。
Pub Date : 2011-01-01 DOI: 10.14236/jhi.v19i3.811
Tim Benson

General practitioner (GP) computing has its origins in the 1970s when the benefits of clinical coding and prescribing were demonstrated. During the early 1980s Dr James Read, working with Abies Informatics Ltd, developed the eponymous Read Codes, which were broader and more comprehensive than other schemes, yet intuitive and easy to use. In 1988 a joint working party of the Royal College of General Practitioners (RCGP) and the British Medical Association (BMA) recommended that the Read Codes be adopted nationally. The Read Codes have been used by almost all GPs in the UK since the mid-1990s. Many developments in general practice, including GP fundholding (where GPs held the budgets to commission elective care for their patients), the Quality and Outcomes Framework (QOF - pay for performance for improving chronic disease management) and GP commissioning (the current NHS reform in which primary care leads commissioning of services for their patients) would have been impossible without all GPs using a common clinical coding scheme. Systematized Nomenclature For Medicine - Clinical Terms (SNOMED CT) is a merger of the Read Codes with SNOMED RT - the original SNOMED reference terminology developed by the American College of Pathologists.

全科医生(GP)计算起源于20世纪70年代,当时临床编码和处方的好处得到了证明。在20世纪80年代早期,James Read博士与Abies Informatics有限公司合作,开发了与之同名的Read代码,它比其他方案更广泛,更全面,但直观且易于使用。1988年,皇家全科医师学院(RCGP)和英国医学协会(BMA)的一个联合工作组建议在全国范围内采用《阅读规范》。自上世纪90年代中期以来,英国几乎所有全科医生都在使用Read Codes。全科医生的许多发展,包括全科医生持有资金(全科医生持有预算,为病人委托选择性护理),质量和结果框架(QOF -改善慢性病管理的绩效支付)和全科医生委托(目前的NHS改革中,初级保健领导为病人委托服务),如果没有所有全科医生使用共同的临床编码方案,是不可能的。系统化医学术语-临床术语(SNOMED CT)是由阅读代码和SNOMED RT合并而成的,SNOMED RT是由美国病理学家学会开发的原始SNOMED参考术语。
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引用次数: 113
Using a data entry clerk to improve data quality in primary care electronic medical records: a pilot study. 使用数据录入员提高初级保健电子医疗记录的数据质量:一项试点研究。
Pub Date : 2011-01-01 DOI: 10.14236/jhi.v19i4.819
Michelle Greiver, Jan Barnsley, Babak Aliarzadeh, Paul Krueger, Rahim Moineddin, Debra A Butt, Edita Dolabchian, Liisa Jaakkimainen, Karim Keshavjee, David White, David Kaplan

Background: The quality of electronic medical record (EMR) data is known to be problematic; research on improving these data is needed.

Objective: The primary objective was to explore the impact of using a data entry clerk to improve data quality in primary care EMRs. The secondary objective was to evaluate the feasibility of implementing this intervention.

Methods: We used a before and after design for this pilot study. The participants were 13 community based family physicians and four allied health professionals in Toronto, Canada. Using queries programmed by a data manager, a data clerk was tasked with re-entering EMR information as coded or structured data for chronic obstructive pulmonary disease (COPD), smoking, specialist designations and interprofessional encounter headers. We measured data quality before and three to six months after the intervention. We evaluated feasibility by measuring acceptability to clinicians and workload for the clerk.

Results: After the intervention, coded COPD entries increased by 38% (P = 0.0001, 95% CI 23 to 51%); identifiable data on smoking categories increased by 27% (P = 0.0001, 95% CI 26 to 29%); referrals with specialist designations increased by 20% (P = 0.0001, 95% CI 16 to 22%); and identifiable interprofessional headers increased by 10% (P = 0.45, 95 CI -3 to 23%). Overall, the intervention was rated as being at least moderately useful and moderately usable. The data entry clerk spent 127 hours restructuring data for 11 729 patients.

Conclusions: Utilising a data manager for queries and a data clerk to re-enter data led to improvements in EMR data quality. Clinicians found this approach to be acceptable.

背景:众所周知,电子病历(EMR)数据的质量存在问题;需要研究如何改进这些数据。目的:主要目的是探讨使用数据录入员对提高初级保健电子病历数据质量的影响。第二个目的是评估实施这一干预措施的可行性。方法:本初步研究采用前后对照设计。参与者是加拿大多伦多的13名社区家庭医生和4名专职保健专业人员。使用由数据管理员编写的查询,数据文员的任务是重新输入电子病历信息,作为慢性阻塞性肺疾病(COPD)、吸烟、专家指定和跨专业会诊标题的编码或结构化数据。我们在干预前和干预后三到六个月测量数据质量。我们通过测量临床医生的可接受性和职员的工作量来评估可行性。结果:干预后,COPD编码条目增加38% (P = 0.0001, 95% CI 23 ~ 51%);可识别的吸烟类别数据增加了27% (P = 0.0001, 95% CI 26 - 29%);专科转诊增加了20% (P = 0.0001, 95% CI 16 - 22%);可识别的跨专业header增加了10% (P = 0.45, 95 CI -3至23%)。总体而言,该干预措施被评为至少中等有用和中等可用。数据录入员花了127个小时重组11729名患者的数据。结论:使用数据管理器进行查询,使用数据办事员重新输入数据,可以提高EMR数据质量。临床医生认为这种方法是可以接受的。
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引用次数: 28
Auditing quality in kidney disease and diabetes: is the precise the enemy of the good? A commentary on difficulties auditing pathology results containing 'greater than' or 'less than' signs. 肾病和糖尿病的审计质量:精确是好事的敌人吗?对包含“大于”或“小于”标志的病理结果审计困难的评论。
Pub Date : 2011-01-01 DOI: 10.14236/jhi.v19i4.813
Simon de Lusignan
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引用次数: 0
Large complex terminologies: more coding choice, but harder to find data--reflections on introduction of SNOMED CT (Systematized Nomenclature of Medicine--Clinical Terms) as an NHS standard. 大型复杂术语:更多编码选择,但更难找到数据——对引入SNOMED CT(系统化医学术语-临床术语)作为NHS标准的思考。
Pub Date : 2011-01-01 DOI: 10.14236/jhi.v19i1.787
Simon de Lusignan, Tom Chan, Simon Jones
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引用次数: 25
Data-modelling and visualisation in chronic kidney disease (CKD): a step towards personalised medicine. 慢性肾脏疾病(CKD)的数据建模和可视化:迈向个体化医疗的一步。
Pub Date : 2011-01-01 DOI: 10.14236/jhi.v19i2.796
Norman Poh, Simon de Lusignan

Background: Personalised medicine involves customising management to meet patients' needs. In chronic kidney disease (CKD) at the population level there is steady decline in renal function with increasing age; and progressive CKD has been defined as marked variation from this rate of decline.

Objective: To create visualisations of individual patient's renal function and display smoothed trend lines and confidence intervals for their renal function and other important co-variants.

Method: Applying advanced pattern recognition techniques developed in biometrics to routinely collected primary care data collected as part of the Quality Improvement in Chronic Kidney Disease (QICKD) trial. We plotted trend lines, using regression, and confidence intervals for individual patients. We also created a visualisation which allowed renal function to be compared with six other covariants: glycated haemoglobin (HbA1c), body mass index (BMI), BP, and therapy. The outputs were reviewed by an expert panel.

Results: We successfully extracted and displayed data. We demonstrated that estimated glomerular filtration (eGFR) is a noisy variable, and showed that a large number of people would exceed the 'progressive CKD' criteria. We created a data display that could be readily automated. This display was well received by our expert panel but requires extensive development before testing in a clinical setting.

Conclusions: It is feasible to utilise data visualisation methods developed in biometrics to look at CKD data. The criteria for defining 'progressive CKD' need revisiting, as many patients exceed them. Further development work and testing is needed to explore whether this type of data modelling and visualisation might improve patient care.

背景:个性化医疗包括定制管理以满足患者的需求。慢性肾脏疾病(CKD)在人群水平上,随着年龄的增长,肾功能稳步下降;进行性慢性肾病被定义为明显偏离这一下降速率。目的:建立单个患者肾功能的可视化,显示其肾功能和其他重要协变的平滑趋势线和置信区间。方法:应用生物识别技术开发的先进模式识别技术,收集常规收集的初级保健数据,这些数据是慢性肾脏疾病质量改善(QICKD)试验的一部分。我们绘制了趋势线,使用回归和个体患者的置信区间。我们还创建了一种可视化方法,可以将肾功能与其他六种协变进行比较:糖化血红蛋白(HbA1c)、体重指数(BMI)、血压和治疗。这些产出由一个专家小组审查。结果:成功提取并显示数据。我们证明估计的肾小球滤过(eGFR)是一个嘈杂的变量,并表明许多人将超过“进行性CKD”标准。我们创建了一个可以很容易自动化的数据显示。我们的专家小组对这种显示器很满意,但在临床测试之前需要进行广泛的开发。结论:利用生物识别技术开发的数据可视化方法来查看CKD数据是可行的。“进行性CKD”的定义标准需要重新审视,因为许多患者超过了标准。需要进一步的开发工作和测试来探索这种类型的数据建模和可视化是否可以改善患者护理。
{"title":"Data-modelling and visualisation in chronic kidney disease (CKD): a step towards personalised medicine.","authors":"Norman Poh,&nbsp;Simon de Lusignan","doi":"10.14236/jhi.v19i2.796","DOIUrl":"https://doi.org/10.14236/jhi.v19i2.796","url":null,"abstract":"<p><strong>Background: </strong>Personalised medicine involves customising management to meet patients' needs. In chronic kidney disease (CKD) at the population level there is steady decline in renal function with increasing age; and progressive CKD has been defined as marked variation from this rate of decline.</p><p><strong>Objective: </strong>To create visualisations of individual patient's renal function and display smoothed trend lines and confidence intervals for their renal function and other important co-variants.</p><p><strong>Method: </strong>Applying advanced pattern recognition techniques developed in biometrics to routinely collected primary care data collected as part of the Quality Improvement in Chronic Kidney Disease (QICKD) trial. We plotted trend lines, using regression, and confidence intervals for individual patients. We also created a visualisation which allowed renal function to be compared with six other covariants: glycated haemoglobin (HbA1c), body mass index (BMI), BP, and therapy. The outputs were reviewed by an expert panel.</p><p><strong>Results: </strong>We successfully extracted and displayed data. We demonstrated that estimated glomerular filtration (eGFR) is a noisy variable, and showed that a large number of people would exceed the 'progressive CKD' criteria. We created a data display that could be readily automated. This display was well received by our expert panel but requires extensive development before testing in a clinical setting.</p><p><strong>Conclusions: </strong>It is feasible to utilise data visualisation methods developed in biometrics to look at CKD data. The criteria for defining 'progressive CKD' need revisiting, as many patients exceed them. Further development work and testing is needed to explore whether this type of data modelling and visualisation might improve patient care.</p>","PeriodicalId":30591,"journal":{"name":"Informatics in Primary Care","volume":"19 2","pages":"57-63"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40165288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Identification of patients with neuropathic pain using electronic primary care records. 使用电子初级保健记录识别神经性疼痛患者。
Pub Date : 2011-01-01 DOI: 10.14236/jhi.v19i2.799
Camille Gajria, Joanna Murray, Ruthie Birger, Ricky Banarsee, David Lh Bennett, Keith Tan, Mark Field, Andrew Sc Rice, Azeem Majeed

Background: Chronic neuropathic pain is a common condition which is challenging to treat. Many people with neuropathic pain are managed in the community, so primary care records may allow more appropriate subjects to be recruited for clinical studies.

Objective: We investigated whether primary care records can be used to identify patients with diseases associated with neuropathic pain.

Method: We analysed demographic, diagnostic and prescribing data from over 100 000 primary care electronic patient records in one part of London, UK.

Results: The prevalence of diagnoses associated with chronic neuropathic pain was 13 per 1000, with the elderly, women and white patients experiencing the greatest burden of disease.

Conclusion: Computerised health records offer an excellent opportunity to improve the identification of patients for clinical research in complex conditions like chronic neuropathic pain. To make full use of data from these records, standardisation of clinical coding and consensus on diagnostic criteria are needed.

背景:慢性神经性疼痛是一种常见病,治疗具有挑战性。许多患有神经性疼痛的人在社区接受治疗,因此初级保健记录可能允许招募更合适的受试者进行临床研究。目的:探讨初级保健记录是否可用于识别神经性疼痛相关疾病的患者。方法:我们分析了人口统计,诊断和处方数据,从超过10万初级保健电子病历在伦敦的一部分,英国。结果:诊断与慢性神经性疼痛相关的患病率为每1000人中有13人,老年人、女性和白人患者承受的疾病负担最重。结论:计算机健康记录为慢性神经性疼痛等复杂疾病的临床研究提供了一个很好的机会。为了充分利用这些记录的数据,需要对临床编码进行标准化,并在诊断标准上达成共识。
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引用次数: 14
Study of electronic prescribing rates and barriers identified among providers using electronic health records in New York City. 纽约市电子处方率和使用电子健康记录的提供者之间确定的障碍的研究。
Pub Date : 2011-01-01 DOI: 10.14236/jhi.v19i2.800
Sam Amirfar, Sheila Anane, Michael Buck, Rachel Cohen, Steve Di Lonardo, Phoenix Maa, Colleen McCullough, Marlena Plagianos, Claudia Pulgarin, John Taverna, Jesse Singer

Background: Increased electronic prescribing (eRx) rates have the potential to prevent errors, increase patient safety, and curtail fraud. US Federal meaningful use guidelines require at least a 40% electronic prescribing rate.

Objective: We evaluated eRx rates among primary care providers in New York City in order to determine trends as well as identify any obstacles to increased eRx rates required by meaningful use guidelines.

Methods: The data we analysed included automatic electronic data transmissions from providers enrolled in the Primary Care Information Project (PCIP) from 1 January 2009 to 1 July 2010 and follow-up telephone calls to a subset of these providers to identify potential barriers to increased eRx usage.

Results: Over the course of the study, these providers increased the eRx rate from 12.9 to 27.5%, with an average rate of 24.1%. Conversations with providers identified their perceived barriers to increased eRx use as primarily patient preference for paper prescriptions and a belief that many pharmacies do not accept eRx.

Conclusions: The data gathered from our providers indicate that there is an increasing trend in the eRx rate to 27.5% by July 2010, but still short of the 40% meaningful use level. However, obstacles to increased rates remain primarily providers' belief that many patients prefer paper prescriptions and many pharmacies are not yet prepared to accept electronic prescriptions.

背景:提高电子处方(eRx)率有可能防止错误,提高患者安全性,并减少欺诈。美国联邦有意义使用指南要求至少40%的电子处方率。目的:我们评估了纽约市初级保健提供者的eRx率,以确定趋势,并确定有意义使用指南要求提高eRx率的任何障碍。方法:我们分析的数据包括2009年1月1日至2010年7月1日在初级保健信息项目(PCIP)登记的提供者的自动电子数据传输,以及对这些提供者的一部分的后续电话呼叫,以确定增加eRx使用的潜在障碍。结果:在研究过程中,这些供应商将eRx率从12.9%提高到27.5%,平均率为24.1%。与供应商的对话确定了他们认为增加eRx使用的障碍,主要是患者偏好纸质处方,并且认为许多药房不接受eRx。结论:从我们的供应商收集的数据表明,到2010年7月,eRx率有上升趋势,达到27.5%,但仍低于40%的有意义使用水平。然而,提高比例的主要障碍仍然是提供者认为许多患者更喜欢纸质处方,而许多药房尚未准备好接受电子处方。
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引用次数: 13
Construction and validation of a scoring system for the selection of high-quality data in a Spanish population primary care database (SIDIAP). 西班牙人口初级保健数据库(SIDIAP)中选择高质量数据的评分系统的构建和验证。
Pub Date : 2011-01-01 DOI: 10.14236/jhi.v19i3.806
M Del Mar García-Gil, Eduardo Hermosilla, Daniel Prieto-Alhambra, Francesc Fina, Magdalena Rosell, Rafel Ramos, Jordi Rodriguez, Tim Williams, Tjeerd Van Staa, Bonaventura Bolíbar

Background: Computerised databases of primary care clinical records are widely used for epidemiological research. In Catalonia, the Information System for the Development of Research in Primary Care (SIDIAP) aims to promote the development of research based on high-quality validated data from primary care electronic medical records.

Objective: The purpose of this study is to create and validate a scoring system (Registry Quality Score, RQS) that will enable all primary care practices (PCPs) to be selected as providers of researchusable data based on the completeness of their registers.

Methods: Diseases that were likely to be representative of common diagnoses seen in primary care were selected for RQS calculations. The observed/expected cases ratio was calculated for each disease. Once we had obtained an estimated value for this ratio for each of the selected conditions we added up the ratios calculated for each condition to obtain a final RQS. Rate comparisons between observed and published prevalences of diseases not included in the RQS calculations (atrial fibrillation, diabetes, obesity, schizophrenia, stroke, urinary incontinence and Crohn's disease) were used to set the RQS cutoff which will enable researchers to select PCPs with research-usable data.

Results: Apart from Crohn's disease, all prevalences were the same as those published from the RQS fourth quintile (60th percentile) onwards. This RQS cut-off provided a total population of 1 936 443 (39.6% of the total SIDIAP population).

Conclusions: SIDIAP is highly representative of the population of Catalonia in terms of geographical, age and sex distributions. We report the usefulness of rate comparison as a valid method to establish research-usable data within primary care electronic medical records.

背景:计算机化的初级保健临床记录数据库被广泛用于流行病学研究。在加泰罗尼亚,初级保健研究发展信息系统(SIDIAP)旨在促进基于初级保健电子医疗记录的高质量有效数据的研究发展。目的:本研究的目的是创建并验证一个评分系统(注册质量评分,RQS),该评分系统将使所有初级保健实践(pcp)能够根据其登记册的完整性被选择为可研究数据的提供者。方法:选择在初级保健中可能具有代表性的常见诊断的疾病进行RQS计算。计算每种疾病的观察/预期病例比。一旦我们获得了每个选定条件下该比率的估计值,我们将每个条件下计算的比率相加,以获得最终的RQS。RQS计算中未包括的疾病(心房纤颤、糖尿病、肥胖、精神分裂症、中风、尿失禁和克罗恩病)的观察和公布的患病率之间的比率比较用于设置RQS截止值,这将使研究人员能够选择具有研究可用数据的pcp。结果:除克罗恩病外,所有的患病率与RQS第四个五分位数(第60百分位)之后公布的患病率相同。这个RQS截止点提供了1 936 443人(占SIDIAP总人口的39.6%)。结论:SIDIAP在地理、年龄和性别分布方面具有高度代表性。我们报告了比率比较作为在初级保健电子病历中建立研究可用数据的有效方法的有效性。
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引用次数: 223
期刊
Informatics in Primary Care
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