Pub Date : 2021-07-01DOI: 10.52547/jarums.21.2.225
Elahe Mamashli, Farnaz Seifi Skishahr, M. Siahkouhian, Manouchehr Iranparvar, A. Asadi, Behzad Davarnia
Background & objectives: Sex impacts the manner in which a person responds to such disease as susceptibility and progression. The aim of this study was to investigate the sex differences in the genotype distribution and allele frequency of some of the adiponectin gene polymorphisms and the comparison of the interaction of the studied polymorphisms and type 2 diabetes-related environment risk factors between males and females. Methods: This study included 103 males and 79 females with type 2 diabetes and 94 healthy males and 61 healthy females for control. Genotyping was performed using amplification refractory mutation system-PCR (T-ARMS-PCR). Statistical analysis was done using SPSS-26.0. The interaction between SNP-SNP and SNPs-environmental factors was analyzed using MDR (version 3.0.2) software. Results: Sex-genotype interaction effect was significantly associated only for triglycerides with SNP-11391G/A ( p = 0.027). For SNP+45T/G, the difference genotypes were distinctly associated with hemoglobin A1c ( p =0.024), body mass index ( p =0.033) and body fat percentage ( p =0.018). For +276G/T fasting insulin level detected a potential difference in genotypes ( p =0.016). Regarding to the results of MDR analysis, the combination of fasting blood glucose, rs17300539 and sex was the best three-factor model. In this model, the distribution of patients according to sex is demonstrated that most men with GA and AA genotypes of -11391G/A had Hemoglobin A1C more than 8.5 while in women there was no relation to genotype found. Conclusion: Sexual difference impact the interaction between adiponectin gene polymorphisms and environmental risk factors. According to the findings of this study, the effect of environmental risk factors on the progression of type 2 diabetes related to Adiponectin gene polymorphisms are demonstrated within the males more than females.
{"title":"Impact of Sex Difference on Interaction between Adiponectin Gene Single Nucleotide Polymorphisms rs2241766, rs17300539 and rs1501299 w Environment Risk Factors of Type 2 Diabetes among the Ardabil Population in Iran","authors":"Elahe Mamashli, Farnaz Seifi Skishahr, M. Siahkouhian, Manouchehr Iranparvar, A. Asadi, Behzad Davarnia","doi":"10.52547/jarums.21.2.225","DOIUrl":"https://doi.org/10.52547/jarums.21.2.225","url":null,"abstract":"Background & objectives: Sex impacts the manner in which a person responds to such disease as susceptibility and progression. The aim of this study was to investigate the sex differences in the genotype distribution and allele frequency of some of the adiponectin gene polymorphisms and the comparison of the interaction of the studied polymorphisms and type 2 diabetes-related environment risk factors between males and females. Methods: This study included 103 males and 79 females with type 2 diabetes and 94 healthy males and 61 healthy females for control. Genotyping was performed using amplification refractory mutation system-PCR (T-ARMS-PCR). Statistical analysis was done using SPSS-26.0. The interaction between SNP-SNP and SNPs-environmental factors was analyzed using MDR (version 3.0.2) software. Results: Sex-genotype interaction effect was significantly associated only for triglycerides with SNP-11391G/A ( p = 0.027). For SNP+45T/G, the difference genotypes were distinctly associated with hemoglobin A1c ( p =0.024), body mass index ( p =0.033) and body fat percentage ( p =0.018). For +276G/T fasting insulin level detected a potential difference in genotypes ( p =0.016). Regarding to the results of MDR analysis, the combination of fasting blood glucose, rs17300539 and sex was the best three-factor model. In this model, the distribution of patients according to sex is demonstrated that most men with GA and AA genotypes of -11391G/A had Hemoglobin A1C more than 8.5 while in women there was no relation to genotype found. Conclusion: Sexual difference impact the interaction between adiponectin gene polymorphisms and environmental risk factors. According to the findings of this study, the effect of environmental risk factors on the progression of type 2 diabetes related to Adiponectin gene polymorphisms are demonstrated within the males more than females.","PeriodicalId":30758,"journal":{"name":"Journal of Ardabil University of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45648174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-01DOI: 10.52547/jarums.21.2.157
Abbas Mousavi, A. Arabmomeni
{"title":"Corrective Exercise; Theraband Exercise; NASM; Water Resistance Training; Flat Foot","authors":"Abbas Mousavi, A. Arabmomeni","doi":"10.52547/jarums.21.2.157","DOIUrl":"https://doi.org/10.52547/jarums.21.2.157","url":null,"abstract":"","PeriodicalId":30758,"journal":{"name":"Journal of Ardabil University of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43765282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-01DOI: 10.52547/jarums.21.2.150
Ahmad Jamei Khosroshahi, Mahmoud Samadi, S. Ghaffari, A. Molaei, Fatemeh Chakari
Background & objectives: Long QT syndrome (LQTS), congenital or acquired disorder, is characterized by a prolonged QT interval associated with syncope attacks and sudden death. Jervell and Lange-Nielsen first described LQTS in conjunction with sensory-neural congenital deafness. In long QT syndrome, the modified QT interval is greater than 440 ms and 460 ms in men and in women respectively. Acquired forms of prolonged QT are the consequence of metabolic disorders and various medications. Since the number of people with congenital deafness in the society is not low and studies in Iran about this syndrome, especially in children are limited, therefore identification of these patients by performing an ECG and simple measures, may be useful in reducing sudden death among these patients. The aim of this study was to determine the prevalence of prolonged QT syndrome in children with congenital sensory-neural deafness which undergoing cochlear implant surgery. Methods: In this study, a single-center cross-sectional observational study, all children with congenital deafness which undergoing cochlear plantation at northwest of Iran were enrolled. Patients' heart rate and QT interval were calculated using Bazett's formula. The association of long QTc with syncope and sudden death, evaluated by using Schwartz's criteria in children with long QT syndrome. Results: Of the 357 studied patients, 204 (57.1%) were male and 153 (42.9%) were female. The mean±SD of the current age of the patients was 7.15±2.93 years with a mean of 7 years. The mean±SD of QT interval in the studied patients was 291.01±26.89 ms with a mean of 280 ms. the mean±SD of the QTc interval in the studied patients was 400.52±25.74 ms with a median of 404 ms. Frequency of Long QTc in the studied patients was 17 cases (4.8%) and long QT syndrome was 5 cases (1.4 %). Conclusion: The prevalence of prolonged QT syndrome in patients with congenital deafness in northwest of Iran in 2019 was 4.8%, and 2 cases had syncope and 3 cases had sudden death.
{"title":"Prevalence of Long QT Syndrome in Children with Congenital Sensory-Neural Deafness","authors":"Ahmad Jamei Khosroshahi, Mahmoud Samadi, S. Ghaffari, A. Molaei, Fatemeh Chakari","doi":"10.52547/jarums.21.2.150","DOIUrl":"https://doi.org/10.52547/jarums.21.2.150","url":null,"abstract":"Background & objectives: Long QT syndrome (LQTS), congenital or acquired disorder, is characterized by a prolonged QT interval associated with syncope attacks and sudden death. Jervell and Lange-Nielsen first described LQTS in conjunction with sensory-neural congenital deafness. In long QT syndrome, the modified QT interval is greater than 440 ms and 460 ms in men and in women respectively. Acquired forms of prolonged QT are the consequence of metabolic disorders and various medications. Since the number of people with congenital deafness in the society is not low and studies in Iran about this syndrome, especially in children are limited, therefore identification of these patients by performing an ECG and simple measures, may be useful in reducing sudden death among these patients. The aim of this study was to determine the prevalence of prolonged QT syndrome in children with congenital sensory-neural deafness which undergoing cochlear implant surgery. Methods: In this study, a single-center cross-sectional observational study, all children with congenital deafness which undergoing cochlear plantation at northwest of Iran were enrolled. Patients' heart rate and QT interval were calculated using Bazett's formula. The association of long QTc with syncope and sudden death, evaluated by using Schwartz's criteria in children with long QT syndrome. Results: Of the 357 studied patients, 204 (57.1%) were male and 153 (42.9%) were female. The mean±SD of the current age of the patients was 7.15±2.93 years with a mean of 7 years. The mean±SD of QT interval in the studied patients was 291.01±26.89 ms with a mean of 280 ms. the mean±SD of the QTc interval in the studied patients was 400.52±25.74 ms with a median of 404 ms. Frequency of Long QTc in the studied patients was 17 cases (4.8%) and long QT syndrome was 5 cases (1.4 %). Conclusion: The prevalence of prolonged QT syndrome in patients with congenital deafness in northwest of Iran in 2019 was 4.8%, and 2 cases had syncope and 3 cases had sudden death.","PeriodicalId":30758,"journal":{"name":"Journal of Ardabil University of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49465700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-01DOI: 10.52547/jarums.21.2.179
Davood Salati Momeni, H. Zandian, H. Ebrahimpour, V. Nemati
Background & objectives: The main motivator of hospitals is manpower. The expansion and complexity of educational medical centers and the appearance of new diseases such as Covid-19 have increased the need for effective management. During the Covid-19 crisis, in which hospitals are at the forefront, special measures should be taken for better management in critical situations. The current study has been conducted with the aim of identifying the main factors affecting management in crisis and its control. Methods: The study method was the "Mix Method" performed in two stages. The first stage was exploratory; in this stage 19 university experts as a research sample were selected by simple random sampling. The second stage was a quantitative, confirmative, and survey study. 202 patients were selected randomly as a research sample from both educational-medical centers involved in Covid-19 of Ardabil city. Data were collected by using a questionnaire. Descriptive analysis of data was performed using SPSS software for heuristic factor analysis, and LISREL software was also used for confirmatory factor analysis and finding correlations between factors. Results: In this study, 17 factors were identified and confirmed, affecting the crisis management in 5 dimensions, including; safety training, crisis control, trust in human resources, sense of vulnerability, the physical and mental health, transparency, justice, participation in decision-making, trust in the manager, honesty, the expectation of needs, efficiency, reward, elimination of stresses, fulfillment of manager's promises, controlling of crisis, inter-sectorial solidity. There was a significant correlation between factors with latent variables. Conclusion: From the perspective of management, being prepared and training the committed forces are very important in controlling the crisis. Manpower plays the main role in the Covid-19 crisis and treating patients, so paying attention to them by considering the factors and dimensions of leadership, social, motivation, organization, and quickness has high importance.
{"title":"Factors Strengthening Covid-19 Crisis Management in Ardabil Educational and Medical Centers","authors":"Davood Salati Momeni, H. Zandian, H. Ebrahimpour, V. Nemati","doi":"10.52547/jarums.21.2.179","DOIUrl":"https://doi.org/10.52547/jarums.21.2.179","url":null,"abstract":"Background & objectives: The main motivator of hospitals is manpower. The expansion and complexity of educational medical centers and the appearance of new diseases such as Covid-19 have increased the need for effective management. During the Covid-19 crisis, in which hospitals are at the forefront, special measures should be taken for better management in critical situations. The current study has been conducted with the aim of identifying the main factors affecting management in crisis and its control. Methods: The study method was the \"Mix Method\" performed in two stages. The first stage was exploratory; in this stage 19 university experts as a research sample were selected by simple random sampling. The second stage was a quantitative, confirmative, and survey study. 202 patients were selected randomly as a research sample from both educational-medical centers involved in Covid-19 of Ardabil city. Data were collected by using a questionnaire. Descriptive analysis of data was performed using SPSS software for heuristic factor analysis, and LISREL software was also used for confirmatory factor analysis and finding correlations between factors. Results: In this study, 17 factors were identified and confirmed, affecting the crisis management in 5 dimensions, including; safety training, crisis control, trust in human resources, sense of vulnerability, the physical and mental health, transparency, justice, participation in decision-making, trust in the manager, honesty, the expectation of needs, efficiency, reward, elimination of stresses, fulfillment of manager's promises, controlling of crisis, inter-sectorial solidity. There was a significant correlation between factors with latent variables. Conclusion: From the perspective of management, being prepared and training the committed forces are very important in controlling the crisis. Manpower plays the main role in the Covid-19 crisis and treating patients, so paying attention to them by considering the factors and dimensions of leadership, social, motivation, organization, and quickness has high importance.","PeriodicalId":30758,"journal":{"name":"Journal of Ardabil University of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47680463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-01DOI: 10.52547/jarums.21.2.214
M. Darvishi, S. Bahrami, Mehdi Zarei, M. Sabaeian
Background & Objectives : Cold Plasma is an emerging non-thermal, chemical-free, environmentally friendly disinfection technology. Plasma-activated water has received considerable attention from researchers in recent years. Despite extensive studies on the antibacterial effects of plasma-activated water, its anti-eukaryotic effects have not been identified. In humans, Acanthamoeba causes granulomatous encephalitis, skin ulcers, and Acanthamoeba keratitis. Considering the health importance of Acanthamoeba , this study investigated the anti-amoeba effect of plasma-activated water on trophozoites and cysts of Acanthamoeba castellanii. Methods : In this study, plasma-activated water prepared by the cold atmospheric plasma method.Physicochemical properties of produced water were evaluated by measuring pH, hydrogen peroxide, nitrite, and nitrate. To assess the effect of plasma-activated water on A. castellanii, trophozoites and cysts were exposed to plasma-activated water for 0.5, 1, 2, 3, 4, and 5 hours. Three replicates were examined each time. At the mentioned times, cell viability was calculated by trypan-blue staining and counting on a hemocytometer, and the results were statistically analyzed. Results : Based on the physicochemical results, the mean pH of plasma-activated water in this study was about 3.4, and the amount of hydrogen peroxide, nitrate, and nitrite were 102, 737, and 36.94 μM, respectively. The present study showed that plasma-activated water killed A. castellanii trophozoites after three hours of exposure and A. castellanii cysts after four hours of exposure. On the other hand, some trophozoites gradually became cysts after exposure to plasma-activated water. These cysts became more resistant to plasma-activated water and inactivated after five hours of exposure. Conclusion : In this study, for the first time, the effect of plasma-activated water on A. castellanii was investigated. The results of the present study showed that plasma-activated water is able to inactivate A. castellanii trophozoites and cysts. Therefore, plasma-activated water can be used to disinfect and inactivate A. castellanii .
{"title":"The Effect of Plasma Activated Water on Acanthamoeba castellanii","authors":"M. Darvishi, S. Bahrami, Mehdi Zarei, M. Sabaeian","doi":"10.52547/jarums.21.2.214","DOIUrl":"https://doi.org/10.52547/jarums.21.2.214","url":null,"abstract":"Background & Objectives : Cold Plasma is an emerging non-thermal, chemical-free, environmentally friendly disinfection technology. Plasma-activated water has received considerable attention from researchers in recent years. Despite extensive studies on the antibacterial effects of plasma-activated water, its anti-eukaryotic effects have not been identified. In humans, Acanthamoeba causes granulomatous encephalitis, skin ulcers, and Acanthamoeba keratitis. Considering the health importance of Acanthamoeba , this study investigated the anti-amoeba effect of plasma-activated water on trophozoites and cysts of Acanthamoeba castellanii. Methods : In this study, plasma-activated water prepared by the cold atmospheric plasma method.Physicochemical properties of produced water were evaluated by measuring pH, hydrogen peroxide, nitrite, and nitrate. To assess the effect of plasma-activated water on A. castellanii, trophozoites and cysts were exposed to plasma-activated water for 0.5, 1, 2, 3, 4, and 5 hours. Three replicates were examined each time. At the mentioned times, cell viability was calculated by trypan-blue staining and counting on a hemocytometer, and the results were statistically analyzed. Results : Based on the physicochemical results, the mean pH of plasma-activated water in this study was about 3.4, and the amount of hydrogen peroxide, nitrate, and nitrite were 102, 737, and 36.94 μM, respectively. The present study showed that plasma-activated water killed A. castellanii trophozoites after three hours of exposure and A. castellanii cysts after four hours of exposure. On the other hand, some trophozoites gradually became cysts after exposure to plasma-activated water. These cysts became more resistant to plasma-activated water and inactivated after five hours of exposure. Conclusion : In this study, for the first time, the effect of plasma-activated water on A. castellanii was investigated. The results of the present study showed that plasma-activated water is able to inactivate A. castellanii trophozoites and cysts. Therefore, plasma-activated water can be used to disinfect and inactivate A. castellanii .","PeriodicalId":30758,"journal":{"name":"Journal of Ardabil University of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45337824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-01DOI: 10.52547/jarums.21.1.113
B. Azadi, Lotfali Boboli, M. Khani, M. Siahkohian, Amaneh Pourrahim
Background & objectives: Insulin-like growth factor -1 (IGF-1) has a variety of roles, but the abundance of scientific evidence indicates that it is a metabolic biomarker associated with physical fitness and health . The present study investigates the effect of eight weeks of polarized exercise training on serum GH / IGF-1- indices in active young men. Methods: In this double-blind experimental study, 20 young males were allocated randomly into polarized training group (N=10) and a control group (N=10). The polarized training group performed 80-70% of the main workout volume (30 minutes) with light to moderate with 50-60% reserve heart rate (RHR) intensity and the remaining 20-30% at 85-95% RHR intensity; in a way that they ran two periods consisting 3 repetitions of 15-30 seconds, with 30-60 seconds of active rest after each repetition and 3 minutes of active rest after each period. Blood samples were taken from all subjects in three stages, including: pre-test stages, 24 hours before the start of the post-test, and after 12 hours overnight fasting. Post-test samples were collected, one sample immediately after the first session and the another 48 hours after the end of the last exercise session. Results: The results of the present study showed that bipolar training significantly increased growth hormone and free IGF-I levels after one training session, and after eight-week bipolar training program. However, total IGF-1 levels decreased significantly after one exercise session and after eight-week bipolar exercise program. Also, no significant change was observed in IGFBP-3 and IGFBP-5 levels after one training session and eight-week training program. Acid-labile subunit levels did not change significantly after one training session, but decreased significantly after eight weeks of bipolar training. Conclusion: Based on the results of the present study, it seems that the use of bipolar exercises, training may be a good way to improve the hormonal function and assess the level of health and physical fitness of active young men.
{"title":"The Effect of Eight Weeks of Polarized Training on GH/IGF-1 Axis Hormones Response in Active Young Male","authors":"B. Azadi, Lotfali Boboli, M. Khani, M. Siahkohian, Amaneh Pourrahim","doi":"10.52547/jarums.21.1.113","DOIUrl":"https://doi.org/10.52547/jarums.21.1.113","url":null,"abstract":"Background & objectives: Insulin-like growth factor -1 (IGF-1) has a variety of roles, but the abundance of scientific evidence indicates that it is a metabolic biomarker associated with physical fitness and health . The present study investigates the effect of eight weeks of polarized exercise training on serum GH / IGF-1- indices in active young men. Methods: In this double-blind experimental study, 20 young males were allocated randomly into polarized training group (N=10) and a control group (N=10). The polarized training group performed 80-70% of the main workout volume (30 minutes) with light to moderate with 50-60% reserve heart rate (RHR) intensity and the remaining 20-30% at 85-95% RHR intensity; in a way that they ran two periods consisting 3 repetitions of 15-30 seconds, with 30-60 seconds of active rest after each repetition and 3 minutes of active rest after each period. Blood samples were taken from all subjects in three stages, including: pre-test stages, 24 hours before the start of the post-test, and after 12 hours overnight fasting. Post-test samples were collected, one sample immediately after the first session and the another 48 hours after the end of the last exercise session. Results: The results of the present study showed that bipolar training significantly increased growth hormone and free IGF-I levels after one training session, and after eight-week bipolar training program. However, total IGF-1 levels decreased significantly after one exercise session and after eight-week bipolar exercise program. Also, no significant change was observed in IGFBP-3 and IGFBP-5 levels after one training session and eight-week training program. Acid-labile subunit levels did not change significantly after one training session, but decreased significantly after eight weeks of bipolar training. Conclusion: Based on the results of the present study, it seems that the use of bipolar exercises, training may be a good way to improve the hormonal function and assess the level of health and physical fitness of active young men.","PeriodicalId":30758,"journal":{"name":"Journal of Ardabil University of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42238796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Hamidian, Elyas Abdollahi, Z. Yazdanpour, Laleh Shahrakimojahed, F. Khademi, H. Vaez
Background and objectives : Urinary tract infection (UTI) is the most prevalent infection and Escherichia coli ( E. coli ) is one of the main causes of UTI worldwide. Integrons are mobile genetic elements considered to be responsible for dissemination of multi-drug resistance infections. Therefore, the aims of this study were to investigate the antibiotic resistance patterns and distribution of class I, II and III integrons among E. coli isolated from patients. Methods : In this descriptive cross-sectional study, from Jun 2020 to March 2021, in total, 70 non-duplicate strains of E. coli were isolated from patients with UTI referred to Amiralmomenin hospital, Zabol, Iran. Antibiotic resistance patterns were determined using Kirby-Bauer’s disk diffusion method and Clinical and Laboratory Standards Institute (CLSI) guidelines. Class I, II and III integrons were detected using polymerase chain reaction (PCR). Results : The isolates showed high resistance toward ampicillin (77.1%), trimethoprim-sulfamethoxazole (58.5%) and ceftriaxone (35%), whereas were mostly susceptible to meropenem (97%). Based on results of PCR, 34 (48.6%) and 3 (4.3%) isolates were classified as class I and class II integron-positive strains, respectively. Conclusion : Resistance rate to ampicillin, ceftriaxone and trimethoprim-sulfamethoxazole was at a high level and their prescription should be restricted. Class I integron is widely distributed among E. coli isolates and play a crucial role in the emergence of antibiotic resistance.
{"title":"Antibiotic Resistance Patterns and Prevalence of Class I, II and III Integrons among Escherichia coli Strains collected from Urinary Tract Infections in Patients Referred to Amiralmomenin Hospital, Zabol, Iran","authors":"K. Hamidian, Elyas Abdollahi, Z. Yazdanpour, Laleh Shahrakimojahed, F. Khademi, H. Vaez","doi":"10.52547/jarums.21.1.66","DOIUrl":"https://doi.org/10.52547/jarums.21.1.66","url":null,"abstract":"Background and objectives : Urinary tract infection (UTI) is the most prevalent infection and Escherichia coli ( E. coli ) is one of the main causes of UTI worldwide. Integrons are mobile genetic elements considered to be responsible for dissemination of multi-drug resistance infections. Therefore, the aims of this study were to investigate the antibiotic resistance patterns and distribution of class I, II and III integrons among E. coli isolated from patients. Methods : In this descriptive cross-sectional study, from Jun 2020 to March 2021, in total, 70 non-duplicate strains of E. coli were isolated from patients with UTI referred to Amiralmomenin hospital, Zabol, Iran. Antibiotic resistance patterns were determined using Kirby-Bauer’s disk diffusion method and Clinical and Laboratory Standards Institute (CLSI) guidelines. Class I, II and III integrons were detected using polymerase chain reaction (PCR). Results : The isolates showed high resistance toward ampicillin (77.1%), trimethoprim-sulfamethoxazole (58.5%) and ceftriaxone (35%), whereas were mostly susceptible to meropenem (97%). Based on results of PCR, 34 (48.6%) and 3 (4.3%) isolates were classified as class I and class II integron-positive strains, respectively. Conclusion : Resistance rate to ampicillin, ceftriaxone and trimethoprim-sulfamethoxazole was at a high level and their prescription should be restricted. Class I integron is widely distributed among E. coli isolates and play a crucial role in the emergence of antibiotic resistance.","PeriodicalId":30758,"journal":{"name":"Journal of Ardabil University of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48716690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohadeseh Rezaei Farahabadi, J. Khodadadi Sangdeh, Sepide Imanian Najafabadi
{"title":"The Phenomenological Identification of the Marital Interactions of People with Coronavirus Disease","authors":"Mohadeseh Rezaei Farahabadi, J. Khodadadi Sangdeh, Sepide Imanian Najafabadi","doi":"10.52547/jarums.21.1.17","DOIUrl":"https://doi.org/10.52547/jarums.21.1.17","url":null,"abstract":"","PeriodicalId":30758,"journal":{"name":"Journal of Ardabil University of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47840915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hossien Daraei, Fatemeh Hazrati Alashti, M. Habibian
Background & objectives: Vitamin D deficiency and poor sleep quality are important factors in health disorders and are common among women. The aim of this study was to investigate the effect of physical activity on vitamin D levels and improving sleep quality in women. Methods: This descriptive-analytical study was conducted on active and inactive women (85 individuals in each group), aged 30-48 years that were selected using convenience randomized sampling. The Pittsburgh Sleep Quality Questionnaire was used to assess sleep quality and a score higher than 5 was determined as poor sleep quality. For analysis of data, Kruskal Wallis and Mann Whitney U tests and Spearman coefficient were used at a significance level of 0.05. Results: The results showed that 54.12% and 28.82% of women had a deficiency and insufficient levels of vitamin D, respectively, and 61.8% had poor sleep quality. Active women had higher levels of vitamin D and better sleep quality compared to inactive women ( p <0.05). There was also a direct relationship between vitamin D levels and sleep quality in active and inactive women. However, this association was significant in active women with vitamin D deficiency and inactive women with different vitamin D status. Conclusion: It seems that physical activity can increase vitamin D levels and improve sleep quality in women. But vitamin D status, especially its deficiency, may be one of the most important determinants of sleep quality in active and inactive women.
{"title":"The Effect of Physical Activity on Vitamin D Levels and Improving Sleep Quality in Women","authors":"Hossien Daraei, Fatemeh Hazrati Alashti, M. Habibian","doi":"10.52547/jarums.21.1.29","DOIUrl":"https://doi.org/10.52547/jarums.21.1.29","url":null,"abstract":"Background & objectives: Vitamin D deficiency and poor sleep quality are important factors in health disorders and are common among women. The aim of this study was to investigate the effect of physical activity on vitamin D levels and improving sleep quality in women. Methods: This descriptive-analytical study was conducted on active and inactive women (85 individuals in each group), aged 30-48 years that were selected using convenience randomized sampling. The Pittsburgh Sleep Quality Questionnaire was used to assess sleep quality and a score higher than 5 was determined as poor sleep quality. For analysis of data, Kruskal Wallis and Mann Whitney U tests and Spearman coefficient were used at a significance level of 0.05. Results: The results showed that 54.12% and 28.82% of women had a deficiency and insufficient levels of vitamin D, respectively, and 61.8% had poor sleep quality. Active women had higher levels of vitamin D and better sleep quality compared to inactive women ( p <0.05). There was also a direct relationship between vitamin D levels and sleep quality in active and inactive women. However, this association was significant in active women with vitamin D deficiency and inactive women with different vitamin D status. Conclusion: It seems that physical activity can increase vitamin D levels and improve sleep quality in women. But vitamin D status, especially its deficiency, may be one of the most important determinants of sleep quality in active and inactive women.","PeriodicalId":30758,"journal":{"name":"Journal of Ardabil University of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45375175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background & objectives: Low birth weight is considered one of the most serious health problems in the world that puts tremendous pressure on the health care system and family. The aim of this study was to investigate the relationship between some maternal risk factors and low birth weight. Methods: The present study was a cross- sectional study performed on 264 cases. The data gathering tool was a checklist with two parts to compare two groups in this research. The first part was related to the infant's characteristics (sex, weight, and gestational age of the newborn), and the second part related to maternal characteristics. Data were analyzed using SPSS software. Inferential statistics including Mann–Whitney u, chi-square, fisher exact test and logistic regression were used to investigate the relationship between the variables. Results: In this study, the level of education was lower in mothers with term low birth weight neonates ( p =0.024), also normal delivery was reported more frequently among mothers with low birth weight infants ( p =0.0001). Also, the mean BMI and the weight at the beginning of pregnancy and overweight in mothers with term neonates and normal weight were greater ( p =0.0001, in all). The first minute Apgar score and the fifth minute Apgar score were lower in mothers with low-birth term infants ( p =0.002 and p =0.0001). Also distinguished that the gestational age (week) was lower in mothers with low-birth term infants ( p =0.0001). Conclusion: According to the results, increasing progress the pregnancy per week makes it possible to increase the normal weight of newborns by 3.11%.
{"title":"Comparison of Maternal predictive factors for Underweight between Low Birth and Normal Weight at Al-Zahra Hospital in Rasht in 2018","authors":"Soudabeh Kazemi Aski, Mandana Mansour Ghanaei, ءohammad Bakhshi, Seddigheh Eghbal","doi":"10.52547/jarums.21.1.41","DOIUrl":"https://doi.org/10.52547/jarums.21.1.41","url":null,"abstract":"Background & objectives: Low birth weight is considered one of the most serious health problems in the world that puts tremendous pressure on the health care system and family. The aim of this study was to investigate the relationship between some maternal risk factors and low birth weight. Methods: The present study was a cross- sectional study performed on 264 cases. The data gathering tool was a checklist with two parts to compare two groups in this research. The first part was related to the infant's characteristics (sex, weight, and gestational age of the newborn), and the second part related to maternal characteristics. Data were analyzed using SPSS software. Inferential statistics including Mann–Whitney u, chi-square, fisher exact test and logistic regression were used to investigate the relationship between the variables. Results: In this study, the level of education was lower in mothers with term low birth weight neonates ( p =0.024), also normal delivery was reported more frequently among mothers with low birth weight infants ( p =0.0001). Also, the mean BMI and the weight at the beginning of pregnancy and overweight in mothers with term neonates and normal weight were greater ( p =0.0001, in all). The first minute Apgar score and the fifth minute Apgar score were lower in mothers with low-birth term infants ( p =0.002 and p =0.0001). Also distinguished that the gestational age (week) was lower in mothers with low-birth term infants ( p =0.0001). Conclusion: According to the results, increasing progress the pregnancy per week makes it possible to increase the normal weight of newborns by 3.11%.","PeriodicalId":30758,"journal":{"name":"Journal of Ardabil University of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49275995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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