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Can Antipsychotics and Antidepressants Affect the Formation or Chronicization of Aortic Dissections? 抗精神病药物和抗抑郁药物会影响主动脉夹层的形成或慢性化吗?
Pub Date : 2021-12-25 DOI: 10.29058/mjwbs.894748
B. Depboylu, B. Harmandar, K. Arslan, S. Yazman
Acute Stanford type-A aortic dissections (STAAD) are life-threatening diseases which require emergency surgery to eliminate risks of aortic rupture, severe aortic valve insufficiency, pericardial tamponade and cerebral and/or coronary malperfusion. Only a small subset of patients go unnoticed and become chronic with unclear mechanism. These patients are usually diagnosed thru late symptoms or incidentally. Surgical techniques requiring cardiopulmonary bypass and sometimes deep hypothermia and circulatory arrest are first-line treatments with considerable mortality and complications. Herein, an incidentally diagnosed chronic STAAD patient who was receiving antipsychotic and antidepressant treatment and successfully repaired with total aortic arch replacement was presented.
急性Stanford a型主动脉夹层(STAAD)是危及生命的疾病,需要紧急手术来消除主动脉破裂、严重主动脉瓣功能不全、心包填塞以及脑和/或冠状动脉灌注不良的风险。只有一小部分患者不被注意,并成为慢性疾病,机制尚不清楚。这些患者通常通过晚期症状或偶然被诊断出来。需要体外循环的外科技术,有时需要深度低温和循环停止,是具有相当高死亡率和并发症的一线治疗方法。本文介绍了一位偶然诊断为慢性STAAD的患者,他接受了抗精神病药物和抗抑郁药物治疗,并成功地进行了全主动脉弓置换术。
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引用次数: 0
Tırnak Altı Lezyonlarında Cerrahi Yaklaşım
Pub Date : 2021-12-25 DOI: 10.29058/mjwbs.905342
A. Gökkaya, Burçin Acuner, Metin Görgü
görülen tümöral lezyonlar Pigmente veya nonpigmente tümörler gözükür ancak sadece muayene benign-malign tümör ayrımının yapılması zordur. Bunun tümöral olmayan bir ganglion beş hastada glomus beş hastada edilen hastanın hastaların tedavi sonucu çok iyi olarak Glomus tümörü olan bir hastada nüks görülmüş ve hasta tekrar opere edilmiştir ve nüks gözlenmemiştir. Sonuç: Tırnak yatağındaki lezyonlar sıklıkla hastalar tarafından göz ardı edilmektedir. Hem benign, hem malign lezyonlar benzer bulgular verebileceğinden tanı için biyopsi alınması şarttır. Uygun tedavi biyopsi sonucuna belirlenmelidir. ABSTRACT different tissues in the nail area, the tumoral lesions seen are quite diverse. Benign tumors that can be pigmented or nonpigmented are usually seen more often, but it is difficult to distinguish between benign and malignant tumors by examination alone. Apart from this, it should be kept in mind that non-tumoral nail diseases should also be included in the differential diagnosis. Material and Methods: In this study, 12 patients who presented to two different centers with the complaint of a mass in the nail between 2009-2020 were included. Clinical findings, treatments and results of the patients were evaluated. Results: Twelve patients with a mean age of 45.9 (34-58) applied to both clinics. 11 of the patients were treated surgically, one patient was not treated. Histopathological diagnosis was ganglion cyst in one patient, glomus tumor in five patients and linear nevus in five patients. In 10 of the 11 operated patients, the treatment result of the patients was evaluated as very good. Recurrence was observed in one patient with glomus tumor and the patient was re-operated and no recurrence was observed. Conclusion: Lesions in the nail bed are often overlooked by patients. Since both benign and malignant lesions may give similar findings, biopsy is essential for diagnosis. The appropriate treatment should be determined according to the biopsy result.
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引用次数: 0
Kronik Radyasyon Maruziyetinin Mean Platelet Volüm (MPV) Üzerine Etkileri
Pub Date : 2021-12-25 DOI: 10.29058/mjwbs.912144
Savaş Volkan Kısıoğlu, Guven Yilmaz
kontrol grubu olarak radyasyon olmayan sağlıklı gönüllüler dâhil tam tetkiki için alınan kan örnekleri etilen diamin tetra asetik asit (EDTA) antikoagülasyonu ile alındı. Periferik yaymaların değerlendirilmesi bir Hematoloji Uzmanı tarafından yapıldı. Tüm olguların tıbbi muayene ve tıbbi bilgileri araştırıcı tarafından kaydedildi. ABSTRACT Aim: In our study, we aimed to examine the effects of chronic low dose radiation exposure on mean platelet volume (MPV). Material and Methods: Patients working in Radiology, Radiation Oncology and Nuclear Medicine Departments and healthy volunteers without radiation exposure were included in the study. Evaluation of peripheral smears was done by a Hematology Specialist. Medical examination and medical information of all cases were recorded by the investigator. Results: 76 cases with radiation exposure and 20 cases without radiation exposure were included in the study. The mean age was 35.54±8.80 in the group with radiation exposure, while the mean age was 30.05±4.97 in the control group. The MPV measurement value of the cases with radiation exposure respectively). Conclusion: Pulmonary problems, hematological problems and other physical problems are routinely evaluated in occupational groups exposed to chronic radiation. However, there is no regular and mandatory examination in terms of atherosclerosis and cardiovascular in these evaluations. we think that employees with chronic radiation exposure should also be followed up in terms of atherosclerotic cardiovascular diseases.
在对照组中,放射免疫试验结果表明,在所有对照组中,都能发现二氨基四乙酸乙二酯(EDTA)抗结核抗体。Periferik yaymaların değerlendirmesi bir Hematoloji Uzmanı tarafından yapıldı.该研究的目标是:通过研究和分析,对乌兹曼人的健康状况进行评估。ABSTRACT Aim: 我们的研究旨在探讨慢性低剂量辐射照射对平均血小板体积(MPV)的影响。材料与方法:研究对象包括在放射科、放射肿瘤科和核医学科工作的患者以及未受辐射照射的健康志愿者。由血液学专家对外周涂片进行评估。研究人员记录了所有病例的体检和医疗信息。结果76例接受过辐射照射,20例未接受过辐射照射。辐照组的平均年龄为(35.54±8.80)岁,对照组的平均年龄为(30.05±4.97)岁。辐照组的 MPV 测量值为(35.54±8.80),对照组的 MPV 测量值为(30.05±4.97)。结论对长期暴露于辐射的职业人群进行肺部问题、血液问题和其他身体问题的常规评估。我们认为,对长期暴露于辐射的员工也应进行动脉粥样硬化性心血管疾病的随访。
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引用次数: 0
Abnormalities of Peripheral Blood Parameters in Hospitalized Patients with COVID-19: A Temporal Change Analysis in Relation to Survival COVID-19住院患者外周血参数异常:与生存相关的时间变化分析
Pub Date : 2021-12-25 DOI: 10.29058/mjwbs.984490
Müzeyyen Aslaner Ak, B. Sahip, G. Celebi, E. Horuz, Ş. Ertop
Abnormalities of peripheral blood parameters in hospitalized patients with COVID-19: A temporal change analysis in relation to survival. Sea. 2021;5(3):391-400. ABSTRACT Aim: This study aimed to investigate the abnormalities and temporal changes in peripheral blood parameters, with particular emphasis on platelet indices, in relation to survival status among hospitalized COVID-19 patients. Material and Methods: A total of 149 patients hospitalized with the diagnosis of COVID-19 were included. Laboratory parameters were recorded on initial admission, 3 rd , 7 th and last day of hospitalization, and post-discharge first month and included hemoglobin (Hb, g/dL), hematocrit (%), white blood cell (WBC) (x109/L), platelet (cells/mm 3 ) and lymphocyte counts (cells/μL), mean platelet volume (MPV, fL), platelet distribution width (PDW, %), plateletcrit (PCT,%) and platelet-to-lymphocyte ratio ( PLR), and analysed. Results: Overall, 139 (93.9%) patients survived. Survivors vs. non-survivors had significantly higher median levels for Hb at initial admission (13.3 vs. 12.2 g/dL, p=0.023), 3 rd day (12.6 vs. 11.7 g/dL, p=0.033) and 7 th day of hospitalization (12.5 vs. 9.8 g/dL, p=0.014) and for lymphocyte counts at initial admission (1200 vs. 800 cells/μL, p=0.014) and 3 rd day (1400 vs. 1200 cells/μL, p=0.043) of hospitalization. They also had significantly lower WBC counts at initial admission (5800 vs. 7900 x109/L, p=0.014), 3 rd day (5400 vs. 6047 x109/L, p=0.007) and 7 th day (6100 vs. 8400 x109/L, p=0.040) and last day (6200 vs. 17700 x109/L, p=0.018) of hospitalization and lower PLR at initial admission (165 vs. 294.5, p=0.002) and 3 rd hospitalization day (150 vs. 223, p=0.003). Conclusion: In conclusion, our findings emphasize clinical significance of dynamic monitoring of peripheral blood parameters, as combined with PLR, in assisting clinicians to identify COVID-19 patients with increased risk of worse outcomes.
COVID-19住院患者外周血参数异常:与生存相关的时间变化分析大海。2021;5(3):391 - 400。摘要目的:本研究旨在探讨COVID-19住院患者外周血指标的异常和时间变化,特别是血小板指标与生存状况的关系。材料与方法:纳入诊断为COVID-19的住院患者149例。记录入院初、住院第3、7、最后一天及出院后第一个月的实验室参数,包括血红蛋白(Hb, g/dL)、红细胞比容(%)、白细胞(WBC) (x109/L)、血小板(细胞/mm 3)和淋巴细胞计数(细胞/μL)、平均血小板体积(MPV, fL)、血小板分布宽度(PDW, %)、血小板比(PCT,%)和血小板淋巴细胞比(PLR),并进行分析。结果:总体而言,139例(93.9%)患者存活。幸存者与非幸存者在入院时Hb的中位水平(13.3 vs 12.2 g/dL, p=0.023)、第3天(12.6 vs 11.7 g/dL, p=0.033)和第7天(12.5 vs 9.8 g/dL, p=0.014)以及入院时淋巴细胞计数(1200 vs 800 cells/μL, p=0.014)和第3天(1400 vs 1200 cells/μL, p=0.043)均显著高于非幸存者。患者入院时WBC计数(5800 vs. 7900 x109/L, p=0.014)、第3天(5400 vs. 6047 x109/L, p=0.007)、第7天(6100 vs. 8400 x109/L, p=0.040)和最后一天(6200 vs. 17700 x109/L, p=0.018)均显著降低,入院时PLR (165 vs. 294.5, p=0.002)和第3天(150 vs. 223, p=0.003)均较低。结论:总之,我们的研究结果强调了动态监测外周血参数并结合PLR帮助临床医生识别COVID-19预后不良风险增加的患者的临床意义。
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引用次数: 1
Doğanın İnsan Yaşamı Üzerine Etkilerinin Karar Ağacı Algoritmaları İle İncelenmesi
Pub Date : 2021-12-25 DOI: 10.29058/mjwbs.895853
Nurhan Halisdemir, Enes Filiz, Y. Güral, M. Gürcan
Aim: The aim of this study is to classify the obtained data correctly using machine learning algorithms. Material and Methods: Happiness, life satisfaction and hopelessness scales with personal information form were applied to 195 patients who came to the psychiatry clinic and wanted to receive psychological treatment due to their anxiety, depression and stress complaints. In this classification, theh happiness core was chosen as the dependent variable and the factors affecting this variable were determined by different methods such as training, test, and cross- validation. Results: KA-RF (0.9180) gave the most successful classification result among decision tree algorithms for k = 10 value. This result is supported by the criteria RMSE (0.2810), ROC area (0.9760) and MCC (0.8400). In addition, the variables that most affect the level of happiness or unhappiness of the participants in the study were found to be life satisfaction, age, and the ability to cope with difficulties, respectively. Conclusion: In line with the findings obtained as a result, it was determined that the effects of environmental and social factors as well as the positive effects of especially living spaces were found in the treatment of anxiety, depression and stress-related disorders.
目的:本研究的目的是使用机器学习算法对获得的数据进行正确分类。材料与方法:对195例因焦虑、抑郁、压力主诉而来到精神科门诊寻求心理治疗的患者,应用幸福感、生活满意度、绝望量表及个人信息表进行问卷调查。在这个分类中,我们选择幸福核心作为因变量,并通过不同的方法,如训练、测试和交叉验证来确定影响这个变量的因素。结果:当k = 10时,KA-RF(0.9180)是决策树算法中分类结果最成功的。该结果得到RMSE(0.2810)、ROC面积(0.9760)和MCC(0.8400)标准的支持。此外,研究还发现,影响研究参与者快乐或不快乐程度的变量分别是生活满意度、年龄和应对困难的能力。结论:根据所获得的结果,确定环境和社会因素的作用以及特别是生活空间的积极作用在治疗焦虑,抑郁和压力相关障碍中被发现。
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引用次数: 0
Medikal ve Endüstriyel Açıdan Kannabinoidlerin Önemi ve Türkiye Ekonomisine Katkı Potansiyeli
Pub Date : 2021-12-25 DOI: 10.29058/mjwbs.928899
Azize Gökgöz, Emine YILMAZ CAN
Cannabis is a plant that offers easy, economical and healthy solutions in basic areas such as industry and medicine. It contains a large number of chemicals, mainly cannabinoids, and has a rich product range. Industrial hemp is used in the production of all kinds of biodegradable plastic materials, in the production of paper-cardboard, in the production of thermal insulation and construction materials, in the textile industry, in the automotive industry, in the manufacture of food and cosmetic products, in the production of biodiesel. Medical cannabis is used for nausea-vomiting due to chemotherapy, neuropathic pain associated with cancer, spasticity associated with multiple sclerosis, weight gain in patients with HIV and in the treatment of some diseases such as epilepsy. In this article, it is aimed to give information about the usage and cultivation of the medical and industrial cannabis plant, which has an important place in our culture, which has been used even by ancient civilizations that have gained popularity in recent years, and also to reveal the potential of cannabis.
大麻是一种在工业和医药等基础领域提供简单、经济和健康解决方案的植物。它含有大量的化学物质,主要是大麻素,产品范围丰富。工业大麻用于生产各种可生物降解塑料材料,用于生产纸板,用于生产隔热和建筑材料,用于纺织工业,汽车工业,用于制造食品和化妆品,用于生产生物柴油。医用大麻用于化疗引起的恶心呕吐、与癌症有关的神经性疼痛、与多发性硬化症有关的痉挛、艾滋病毒患者的体重增加以及癫痫等某些疾病的治疗。在这篇文章中,它的目的是提供关于医用和工业大麻植物的使用和种植的信息,大麻在我们的文化中占有重要地位,甚至在近年来流行起来的古代文明中也有使用,并揭示大麻的潜力。
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引用次数: 1
The Nurse’s Role in Preventing Ventilator-Associated Pneumonia 护士在预防呼吸机相关性肺炎中的作用
Pub Date : 2021-12-25 DOI: 10.29058/mjwbs.936579
Canan KAŞ GÜNER, S. Kutlutürkan
Ventilator-associated pneumonia(VAP) is an important condition constituting the half of the hospital- originated pneumonia cases. The ventilator-associated pneumonia can result from microorganisms in the patient’s own flora, visitors, hospital staff, other patients and environmental factors. Elimination ofventilator-associated pneumonia, which causes high mortality rates, prolonged hospitalizations, excessive use of antibiotics and consequently increased health expenditures in adult patients with endotracheal intubation worldwide, is possible with multidisciplinary team work. In this adversaria, it is thought that the methods applied to eliminate the risk of ventilator-associated pneumonia and nursing practices will contribute to direct the care practices of the staff in charge and affect the patient care results positively. pnömoni (VİP), pnömoni Ventilatörle hastanın hastane çalışanlarından, diğer hastalardan çevresel endotrakeal yetişkin mortalite antibiyotik ventilatörle pnömoninin, risk faktörlerinin ortadan kaldırılması mutidisipliner çalışması mümkündür. Bu derlemede, ventilatörle ilişkili pnömoni riskini ortadan kaldırmak için uygulanan yöntemler hemşirelik uygulamaları Ventilatörle Risk Önleme,
呼吸机相关性肺炎(VAP)是医院源性肺炎的重要疾病,占医院源性肺炎病例的一半。呼吸机相关性肺炎可由患者自身菌群、访客、医院工作人员、其他患者和环境因素中的微生物引起。在世界范围内,呼吸机相关性肺炎会导致高死亡率、长期住院、过度使用抗生素并因此增加气管插管成人患者的卫生支出。通过多学科团队合作,消除呼吸机相关性肺炎是可能的。本文认为,消除呼吸机相关性肺炎风险的方法和护理实践将有助于指导主管人员的护理实践,并对患者的护理结果产生积极影响。pnomoni (VİP), pnomoni Ventilatorle hastanın hastane卡尔ışanlarından, diğer hastalardan cevresel endotrakeal雪人ş亲属mortalite antibiyotik Ventilatorle pnomoninin,风险faktorlerinin ortadan kaldırılmaımutidisipliner卡尔ışmasımumkundur。但是derlemede, ventilatörle ili kili pnömoni riskini ortadan kaldırmak iin uygulanan yöntemler hemirelik uygulamalaryi Ventilatörle Risk Önleme,
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引用次数: 1
Tıp Fakültesi Öğrencilerinde Cinsel Mitlere İnanma Durumu ve İlişkili Faktörler
Pub Date : 2021-12-25 DOI: 10.29058/mjwbs.945816
Vildan ÇAKIR KARDEŞ, Serkan Bostanci, Ceren Aktaş, Bahadır Ay, M. Gürcan, Dilara Yi̇ği̇t, Yasemin Özdemir, Halil Çetin, Mustafa Ozan Avşar, Emre Enes Bekteş, Berkay Öz, Burak Karasu, A. Uzun
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引用次数: 0
Mamografide Mikrokalsifikasyon Tespit Edilen Hastalarda Kontrastlı Spektral Mamografi ile Dinamik Meme MRG’nin Etkinliğinin Karşılaştırılması: Tek Merkez Deneyimi
Pub Date : 2021-12-25 DOI: 10.29058/mjwbs.960285
Kamber Göksu, A. Vural
Aim: The aim of this study is to compare the diagnostic performance of contrast-enhanced spectral mammography (CESM) and breast magnetic resonance imaging (MRI) in patients with microcalcification detected by mammography. CESM and MRI the for in the study, the that the were diagnosed histopathologically and that both CESM and Breast were performed were sought. The presence of pathological enhancement for CESM and Breast MRI compared statistically using the Fisher-Freeman-Halton Exact test together with histopathological diagnosis. CESM and Breast MRI examinations were performed in 75 patients with microcalcifications. Pathological contrast enhancement was detected in 47 cases in breast MRI examinations of these patients. With CESM examination, 49 patients had contrast enhancement in the microcalcification region. Forty-seven patients with contrast enhancement with both examinations were common. Contrast enhancement rates of those who were found benign as a result of the biopsy were the same for CESM and MRI (48.9%). Contrast enhancement rates of malignant ones for CESM, 88% for MRI, and 60% for CESM and Breast MRI for premalignant lesions. When contrast enhancement of the lesions was compared according to the biopsy results, no statistically significant difference was found for CESM and Breast MRI. Conclusion: CESM shows less background enhancement and has a similar sensitivity to breast MRI in detecting breast cancer. CESM is an easily accessible alternative to Breast MRI and the procedure time is significantly shorter. For these reasons, it has the potential to play an important role in breast cancer detection and staging.
目的:本研究的目的是比较对比增强光谱乳房x线摄影(CESM)和乳房磁共振成像(MRI)对乳房x线摄影检测到的微钙化患者的诊断效果。在研究中,CESM和MRI是最重要的,组织病理学诊断和CESM和乳腺检查都是最重要的。使用Fisher-Freeman-Halton精确测试和组织病理学诊断,CESM和乳腺MRI病理增强的存在进行统计学比较。对75例微钙化患者进行了CESM和乳腺MRI检查。47例乳腺MRI检查发现病理对比增强。经CESM检查,49例患者微钙化区造影增强。47例患者在两项检查中均有增强。活检结果显示为良性的对比增强率CESM和MRI相同(48.9%)。CESM对恶性病变的对比增强率,MRI为88%,CESM和乳腺MRI对癌前病变的对比增强率为60%。根据活检结果对病变进行对比增强时,CESM与乳腺MRI无统计学差异。结论:CESM对乳腺癌的本底增强效果较小,与乳腺MRI的敏感性相近。CESM是一种容易获得的替代乳房MRI的方法,而且手术时间明显缩短。由于这些原因,它有可能在乳腺癌的检测和分期中发挥重要作用。
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引用次数: 0
COVID-19 Re-Enfekte Hastada Periorbital Herpes Zoster Duplex Bilateralis Birlikteliği
Pub Date : 2021-12-25 DOI: 10.29058/mjwbs.956727
Göktuğ Demirci, Gülşen TÜKENMEZ DEMİRCİ
Aim: Varicella-zoster computer virus (VZV) is a human neurotrophic computer and Herpes Zoster (HZ) is a retargeted selection from potential target in the dorsal root ganglion of a bred varicella VZV. Urticaria, which becomes common when COVID-19 grows, has been observed where papule-vesicular eruptions such as chicken pox and days appearing as HZ are observed. Unilateral herpes zoster duplex unilateralis when in two non-adjacent dermatomes; If it is bilateral, it is called bilateral. Case: A 39-year-old female patient was admitted to our clinic with high fever, weakness, cough, shortness of breath and rash on both eyelids. It was learned from the patient’s anamnesis that he had COVID-19 infection and simultaneous facial paralysis three months ago. As a result of the dermatological examination, it was thought that grouped vesicular lesions on the erythematous background on the bilateral upper eyelid were compatible with HZ duplex bilateralis. At the end of the 14 th day, the patient was discharged after the signs of COVID-19 infection disappeared and the skin lesions healed completely. bireyler, ila kat fazla risk taşırlar (5). Bu tipik olarak, ağrılı, taraflı, eritematöz fazla vakalar, özellikle bağışıklığı yeterli nadirdir (<%0.5) (6). Tek taraflı dermatom etkilenirse Herpes zoster duplex unilateralis, iki taraflı dermatom ise Herpes zoster duplex bilateralis olarak adlandırılır (7). Conclusion: Although our case was immunocompetent, it is noteworthy that she was diagnosed with HZ duplex bilateralis on the upper while she was infected with COVID 19 for the second time. The coexistence of COVID 19 infection and HZ duplex bilateralis has not been reported in the literature so far. It should not be ignored that HZ infection may occur with unusual involvements in patients infected with COVID-19.
目的:水痘-带状疱疹计算机病毒(VZV)是一种人类神经营养计算机,带状疱疹病毒(HZ)是水痘-带状疱疹病毒(VZV)的一种重靶向选择,它是水痘-带状疱疹病毒(VZV)在繁殖后的背根神经节中的潜在靶点。随着新冠肺炎的扩散,荨麻疹变得很常见。在荨麻疹中,会出现水痘等丘疹-水疱疹,出现HZ样的天数。单侧带状疱疹双单侧发生于两个不相邻的皮节;如果是双边的,就叫双边的。病例:一名39岁女性患者因高热、虚弱、咳嗽、呼吸急促及双眼睑起疹而入院。从患者的记忆中得知,他在3个月前感染了新冠病毒,并同时患有面瘫。由于皮肤病学检查的结果,我们认为在双侧上眼睑红斑背景上的分组水疱病变与HZ双侧肌相一致。第14天,患者感染症状消失,皮肤病变完全愈合后出院。butipik olarak, ağrılı, taraflyi, eritematöz fazla vakalar, özellikle bağışıklığı yeterli nadirdir (<%0.5) (6). Tek taraflyi dermatom etkilenirse单侧带状疱疹双相,iki taraflyi dermatom ise双侧带状疱疹双相olarak adlandırılır(7)结论:虽然我们的病例免疫功能正常,但值得注意的是,她在第二次感染COVID - 19时被诊断为上肢双侧带状疱疹。目前文献未见新冠病毒感染与双侧HZ共存的报道。不应忽视的是,在感染COVID-19的患者中可能发生HZ感染并伴有异常累及。
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引用次数: 0
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Medical Journal of Western Black Sea
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