E. Gökçe, S. T. Tanrıverdi, Ipek Eroglu, N. Tsapis, G. Gokce, E. Fattal, Ö. Özer
Evren H. Gokce, Sakine Tuncay Tanrıverdi, Ipek Eroglu, Nicolas Tsapis, Goksel Gokce, Elias Fattal, Ozgen Ozer Department of Pharmaceutical Technology, Faculty of Pharmacy, Ege University 35100, Bornova, Izmir, Turkey evrenhomangokce@gmail.com; sakinetuncay@windowslive.com Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Hacettepe University 06100 Ankara, Turkey Institut Galien Paris-Sud, CNRS, Univ. Paris-Sud, Université Paris-Saclay 92296 Châtenay-Malabry, France Department of Pharmacology, Faculty of Pharmacy, Ege University 35100, Bornova, Izmir, Turkey
Evren H. Gokce, Sakine Tuncay Tanrıverdi, Ipek Eroglu, Nicolas Tsapis, Goksel Gokce, Elias Fattal, Ozgen Ozer 35100土耳其伊兹密尔博尔诺瓦市埃格大学药学院制药技术系evrenhomangokce@gmail.com;sakinetuncay@windowslive.com土耳其安卡拉Hacettepe大学药学院基础药学系，06100;法国巴黎南部大学，法国巴黎萨克雷大学;法国巴黎南部大学，法国巴黎萨克雷大学92296;法国埃格大学药学院药学系，土耳其伊兹密尔Bornova 35100
{"title":"A Novel Alternative for the Treatment of Diabetic Foot Wounds: A Three Dimensional Porous Dermal Matrix","authors":"E. Gökçe, S. T. Tanrıverdi, Ipek Eroglu, N. Tsapis, G. Gokce, E. Fattal, Ö. Özer","doi":"10.11159/nddte17.121","DOIUrl":"https://doi.org/10.11159/nddte17.121","url":null,"abstract":"Evren H. Gokce, Sakine Tuncay Tanrıverdi, Ipek Eroglu, Nicolas Tsapis, Goksel Gokce, Elias Fattal, Ozgen Ozer Department of Pharmaceutical Technology, Faculty of Pharmacy, Ege University 35100, Bornova, Izmir, Turkey evrenhomangokce@gmail.com; sakinetuncay@windowslive.com Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Hacettepe University 06100 Ankara, Turkey Institut Galien Paris-Sud, CNRS, Univ. Paris-Sud, Université Paris-Saclay 92296 Châtenay-Malabry, France Department of Pharmacology, Faculty of Pharmacy, Ege University 35100, Bornova, Izmir, Turkey","PeriodicalId":31009,"journal":{"name":"RAN","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91097451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Extended Abstract Fluorine compounds have been highlighted as a warming gas caused the global warming. These Fluorine compounds, such as NF3, etc., are commonly emitted from semiconductor and LCD manufacturing industries. This study gave assessment of catalytic hydrolysis for the effective decomposition of NF3 [1, 2]. AlF3 nano-structures with various morphologies, which were synthesized by various synthesis methods, were used as the catalyst for the hydrolysis of NF3. AlF3 with a nano-needle type was synthesized by a gas-solid reaction, and AlF3 with a large-sized rod type was synthesized using the wet chemical method. The catalytic activity tests were carried out in a fixed-bed reactor, and the content of NF3 and GHSV were fixed to 5000 ppmv, and 15000 h, respectively. Steam was injected at a volumetric ratio of NF3 / H2O = 1 / 3 via syringe pump. The characterization of AlF3 used as the catalyst for hydrolysis of NF3 was observed by XRD (X-ray diffraction), SEM (scanning electron microscopy) and BET (Brunauer-Emmett-Teller) surface areas measurements. The AlF3 structures with various morphologies, such as rod, needle, and spherical types, were observed. The AlF3 samples of most structures had a very low surface area and their surface area showed no significant difference. On the other hand, the results of the activity tests for the hydrolysis of NF3 over AlF3 with different morphologies showed different catalytic activity. The conversion of NF3 over the spherical type AlF3 was kept at approximately 30 %. In contrast, the catalytic activity of needle-shaped AlF3 resulted in 100% NF3 conversion. The activity was maintained for more than 300 h in the long-term tests. The hexagonal crystal structure of AlF3 (25.321°, 42.715°, 51.997°, and 58.118° 2θ) was confirmed by XRD analysis of all AlF3 samples used in this study. The orthorhombic crystal structure of AlF3 (14.747°, 24.943°, 29.746°, 47.463°, and 52.790° 2θ) was confirmed only on the XRD peak pattern of AlF3 synthesized by the wet fluorination process. The commercial AlF3 and AlF3 nanostructure synthesized by the dry fluorination process exhibited a similar XRD peak pattern, but the peak intensity of the commercial AlF3 on the XRD peak pattern of the hexagonal crystal structure was higher than that of the other AlF3 samples. The hexagonal structure of AlF3 has higher catalytic activity for the hydrolysis of NF3 than the orthorhombic structure of AlF3. Although the hexagonal structure of AlF3 had a high catalytic activity for the hydrolysis of NF3, the needle-like shaped hexagonal structure of AlF3 had higher catalytic activity than the other shaped hexagonal structures. The hexagonal structure of AlF3 has higher catalytic activity for the hydrolysis of NF3 than the orthorhombic structure of AlF3. Therefore, the needlelike shaped AlF3 with high catalytic activity can be prepared by a dry fluorination process.
{"title":"Activity Test with Various AlF3 Nano-Structure for Catalytic Hydrolysis of NF3","authors":"N. Park, Yong Han Jeong, T. Lee","doi":"10.11159/icnnfc17.112","DOIUrl":"https://doi.org/10.11159/icnnfc17.112","url":null,"abstract":"Extended Abstract Fluorine compounds have been highlighted as a warming gas caused the global warming. These Fluorine compounds, such as NF3, etc., are commonly emitted from semiconductor and LCD manufacturing industries. This study gave assessment of catalytic hydrolysis for the effective decomposition of NF3 [1, 2]. AlF3 nano-structures with various morphologies, which were synthesized by various synthesis methods, were used as the catalyst for the hydrolysis of NF3. AlF3 with a nano-needle type was synthesized by a gas-solid reaction, and AlF3 with a large-sized rod type was synthesized using the wet chemical method. The catalytic activity tests were carried out in a fixed-bed reactor, and the content of NF3 and GHSV were fixed to 5000 ppmv, and 15000 h, respectively. Steam was injected at a volumetric ratio of NF3 / H2O = 1 / 3 via syringe pump. The characterization of AlF3 used as the catalyst for hydrolysis of NF3 was observed by XRD (X-ray diffraction), SEM (scanning electron microscopy) and BET (Brunauer-Emmett-Teller) surface areas measurements. The AlF3 structures with various morphologies, such as rod, needle, and spherical types, were observed. The AlF3 samples of most structures had a very low surface area and their surface area showed no significant difference. On the other hand, the results of the activity tests for the hydrolysis of NF3 over AlF3 with different morphologies showed different catalytic activity. The conversion of NF3 over the spherical type AlF3 was kept at approximately 30 %. In contrast, the catalytic activity of needle-shaped AlF3 resulted in 100% NF3 conversion. The activity was maintained for more than 300 h in the long-term tests. The hexagonal crystal structure of AlF3 (25.321°, 42.715°, 51.997°, and 58.118° 2θ) was confirmed by XRD analysis of all AlF3 samples used in this study. The orthorhombic crystal structure of AlF3 (14.747°, 24.943°, 29.746°, 47.463°, and 52.790° 2θ) was confirmed only on the XRD peak pattern of AlF3 synthesized by the wet fluorination process. The commercial AlF3 and AlF3 nanostructure synthesized by the dry fluorination process exhibited a similar XRD peak pattern, but the peak intensity of the commercial AlF3 on the XRD peak pattern of the hexagonal crystal structure was higher than that of the other AlF3 samples. The hexagonal structure of AlF3 has higher catalytic activity for the hydrolysis of NF3 than the orthorhombic structure of AlF3. Although the hexagonal structure of AlF3 had a high catalytic activity for the hydrolysis of NF3, the needle-like shaped hexagonal structure of AlF3 had higher catalytic activity than the other shaped hexagonal structures. The hexagonal structure of AlF3 has higher catalytic activity for the hydrolysis of NF3 than the orthorhombic structure of AlF3. Therefore, the needlelike shaped AlF3 with high catalytic activity can be prepared by a dry fluorination process.","PeriodicalId":31009,"journal":{"name":"RAN","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76721240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Specular Reflection Structural Colors Effect for Nano Hole Array of Various Depth and by Light Source","authors":"W. Jang, Y. Seo, B. Kim","doi":"10.11159/icnnfc17.106","DOIUrl":"https://doi.org/10.11159/icnnfc17.106","url":null,"abstract":"","PeriodicalId":31009,"journal":{"name":"RAN","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84763260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Ficai, M. Sonmez, A. Ficai, I. Ardelean, E. Andronescu
Denisa Ficai, Maria Sonmez, Anton Ficai, Ioana Lavinia Ardelean, Ecaterina Andronescu Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest Polizu Street no 1-7, 011061, Bucharest, Romania denisa.ficai@upb.ro; ficaimaria@yahoo.com National Research and Development Institute for Textiles and Leather–division: Leather and Footwear Research Institute, Bucharest, Romania
Denisa Ficai, Maria Sonmez, Anton Ficai, Ioana Lavinia Ardelean, Ecaterina Andronescu布加勒斯特理工大学应用化学与材料科学学院氧化材料与纳米材料科学与工程系，布加勒斯特Polizu街1-7号，011061，罗马尼亚denisa.ficai@upb.ro;ficaimaria@yahoo.com国家纺织和皮革研究与发展研究所:皮革和鞋类研究所，布加勒斯特，罗马尼亚
{"title":"Harnessing PET Wastes by Compounding with Functionalized Flax","authors":"D. Ficai, M. Sonmez, A. Ficai, I. Ardelean, E. Andronescu","doi":"10.11159/ICNNFC17.136","DOIUrl":"https://doi.org/10.11159/ICNNFC17.136","url":null,"abstract":"Denisa Ficai, Maria Sonmez, Anton Ficai, Ioana Lavinia Ardelean, Ecaterina Andronescu Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest Polizu Street no 1-7, 011061, Bucharest, Romania denisa.ficai@upb.ro; ficaimaria@yahoo.com National Research and Development Institute for Textiles and Leather–division: Leather and Footwear Research Institute, Bucharest, Romania","PeriodicalId":31009,"journal":{"name":"RAN","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84936300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emerging Cu-based materials are explored to benefit from the energetically high-lying Cu d-state in combination with low effective mass of the minority carriers. Materials with higher functionality open for ultrathin devices and thereby less raw material usage. In this talk, we discuss the details in the optoelectronic properties of emerging Cu-based chalcopyrites, like for instance Cu2(Sn,Ge)S3, Cu3Sb(S,Se)3, Cu3Bi(S,Se)3, and Cu2XSnS4 (X = transition metal atom), employing hybrid functionals within the density functional theory. We analyze the electronic structure and the optical properties in terms of the absorption coefficients. By modeling the maximum device efficiency with respect to film thickness, we further discuss the optoelectronic response. The results help to understand fundamental physics of the Cu-based compounds in order to design and optimize very thin solar-energy devices.
{"title":"Tailor-Making Chalcopyrite Alloys for 100-Nm Thin Solar Cells","authors":"C. Persson","doi":"10.11159/ICNEI17.1","DOIUrl":"https://doi.org/10.11159/ICNEI17.1","url":null,"abstract":"Emerging Cu-based materials are explored to benefit from the energetically high-lying Cu d-state in combination with low effective mass of the minority carriers. Materials with higher functionality open for ultrathin devices and thereby less raw material usage. In this talk, we discuss the details in the optoelectronic properties of emerging Cu-based chalcopyrites, like for instance Cu2(Sn,Ge)S3, Cu3Sb(S,Se)3, Cu3Bi(S,Se)3, and Cu2XSnS4 (X = transition metal atom), employing hybrid functionals within the density functional theory. We analyze the electronic structure and the optical properties in terms of the absorption coefficients. By modeling the maximum device efficiency with respect to film thickness, we further discuss the optoelectronic response. The results help to understand fundamental physics of the Cu-based compounds in order to design and optimize very thin solar-energy devices.","PeriodicalId":31009,"journal":{"name":"RAN","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90504373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Extended Abstract Fibroin is the structural protein of silk fibres that has been used for suture materials for decades [1]. Core-shell structured micro/nanoparticles of submicron size were prepared from fibroin without any chemical cross-linking [2]. Fibroin-shell microspheres with a fluorescent core were used to evaluate cellular uptake and to trace intracellular trafficking in murine 3T3 cells [3]. Animal cells that ingested Fe3O4-containg microspheres have been used to prepare a scaffold-free three-dimensional (3D) culture of animal cells [4, 5]. In this report, we further investigated fibroin micro/nanosphere uptake and multicellular aggregate formation using a variety of cells and cell lines. The percentage of cells that ingested fibroin microspheres varied significantly depending on the cells used. The efficiency of microsphere uptake was in the order of human mesenchymal stem cell, murine fibroblast 3T3, monocyte Raw264.7, murine melanocyte B16F10 and human dermal fibroblast. Diskor spheroidshaped multicellular aggregates were obtained by magnetic levitation of cells ingested Fe3O4-containg microspheres. A disk-shaped multicellular surface culture up to 15 mm in diameter was obtained using B16F10 cells and a spheroid up to 3.5 mm in diameter was made from 3T3 cells. Microscopic study showed that Fe3O4-containg microspheres aligned parallel to the magnetic field and that a necrotic core was developed in 3T3 spheroids possibly due to diffusion limitation of nutrient or oxygen. Micro CT scan also revealed that Fe3O4 distribution was not uniform throughout the spheroid. While, B16F10 and Raw264.7 cells showed surface growth at the air-medium interface, which is hardly observed in animal cell cultures. The present approach produced millimetre-scale multicellular spheroids or multilayer cell cultures depending on cells used, which has a potential being developed to surrogate tissue for toxicant monitoring, for extracellular matrix synthesis and for differentiation study.
{"title":"Cellular Uptake of Fibroin Micro/Nanoparticles as a Method for Three-Dimensional Culture under Magnetic Levitation Conditions","authors":"Jae Kwon Shim, W. Hur","doi":"10.11159/NDDTE17.115","DOIUrl":"https://doi.org/10.11159/NDDTE17.115","url":null,"abstract":"Extended Abstract Fibroin is the structural protein of silk fibres that has been used for suture materials for decades [1]. Core-shell structured micro/nanoparticles of submicron size were prepared from fibroin without any chemical cross-linking [2]. Fibroin-shell microspheres with a fluorescent core were used to evaluate cellular uptake and to trace intracellular trafficking in murine 3T3 cells [3]. Animal cells that ingested Fe3O4-containg microspheres have been used to prepare a scaffold-free three-dimensional (3D) culture of animal cells [4, 5]. In this report, we further investigated fibroin micro/nanosphere uptake and multicellular aggregate formation using a variety of cells and cell lines. The percentage of cells that ingested fibroin microspheres varied significantly depending on the cells used. The efficiency of microsphere uptake was in the order of human mesenchymal stem cell, murine fibroblast 3T3, monocyte Raw264.7, murine melanocyte B16F10 and human dermal fibroblast. Diskor spheroidshaped multicellular aggregates were obtained by magnetic levitation of cells ingested Fe3O4-containg microspheres. A disk-shaped multicellular surface culture up to 15 mm in diameter was obtained using B16F10 cells and a spheroid up to 3.5 mm in diameter was made from 3T3 cells. Microscopic study showed that Fe3O4-containg microspheres aligned parallel to the magnetic field and that a necrotic core was developed in 3T3 spheroids possibly due to diffusion limitation of nutrient or oxygen. Micro CT scan also revealed that Fe3O4 distribution was not uniform throughout the spheroid. While, B16F10 and Raw264.7 cells showed surface growth at the air-medium interface, which is hardly observed in animal cell cultures. The present approach produced millimetre-scale multicellular spheroids or multilayer cell cultures depending on cells used, which has a potential being developed to surrogate tissue for toxicant monitoring, for extracellular matrix synthesis and for differentiation study.","PeriodicalId":31009,"journal":{"name":"RAN","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82924248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mathieu Menta, I. Calle, François Auger, Marlène Klein, F. Séby
Nanomaterials (NM) open huge prospects for innovation in different fields such as medicine, electronics, cosmetics and materials. However, their uses raise questions about possible risks to the environment and humans. The development of suitable protocols for the physicochemical characterization (size distribution, shape and chemical composition) of such materials is a fundamental issue for coming years. To meet the needs of various industrials producing or using NM, UT2A has developed new analytical approaches. The first one is focused on the determination of the size distribution of nano-scale particles using Dynamic Light Scattering detector (DLS) and a splitting system (by size and weight) such as Asymmetrical Flow Field Flow Fractionation hyphenated with a Multi Angle Laser Light Scattering detector (A4F-MALLS). The second approach is based on a comprehensive physicochemical characterization made by the combination of A4F-MALLS with an UV detector and an Inductively Coupled Plasma Mass Spectrometer (ICP-MS). The Single Particle-ICPMS has also been used to characterize NM. This study is first focused on the characterization of NM in consumer products such as sunscreens, candies or juices. The results obtained by the different analytical approaches are also discussed. Then the same techniques were used for environmental (colloids and NPs in effluent processes) and pharmaceutical applications. This work has enabled to develop and validate an approach to global physicochemical characterization of nanomaterials in complex matrices.
{"title":"Analytical Developments for the Characterization of Nanomaterials in Consumer Products, Environmental and Medicinal Samples","authors":"Mathieu Menta, I. Calle, François Auger, Marlène Klein, F. Séby","doi":"10.11159/ICNNFC17.120","DOIUrl":"https://doi.org/10.11159/ICNNFC17.120","url":null,"abstract":"Nanomaterials (NM) open huge prospects for innovation in different fields such as medicine, electronics, cosmetics and materials. However, their uses raise questions about possible risks to the environment and humans. The development of suitable protocols for the physicochemical characterization (size distribution, shape and chemical composition) of such materials is a fundamental issue for coming years. To meet the needs of various industrials producing or using NM, UT2A has developed new analytical approaches. The first one is focused on the determination of the size distribution of nano-scale particles using Dynamic Light Scattering detector (DLS) and a splitting system (by size and weight) such as Asymmetrical Flow Field Flow Fractionation hyphenated with a Multi Angle Laser Light Scattering detector (A4F-MALLS). The second approach is based on a comprehensive physicochemical characterization made by the combination of A4F-MALLS with an UV detector and an Inductively Coupled Plasma Mass Spectrometer (ICP-MS). The Single Particle-ICPMS has also been used to characterize NM. This study is first focused on the characterization of NM in consumer products such as sunscreens, candies or juices. The results obtained by the different analytical approaches are also discussed. Then the same techniques were used for environmental (colloids and NPs in effluent processes) and pharmaceutical applications. This work has enabled to develop and validate an approach to global physicochemical characterization of nanomaterials in complex matrices.","PeriodicalId":31009,"journal":{"name":"RAN","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84999315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Designing Membrane-Active Nanoparticles: What are the Control Parameters?","authors":"V. Baulin","doi":"10.11159/ICNB17.1","DOIUrl":"https://doi.org/10.11159/ICNB17.1","url":null,"abstract":"","PeriodicalId":31009,"journal":{"name":"RAN","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79347536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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