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INTESTINAL DYSBIOSIS, HUMAN HEALTH AND FUNCTIONAL NUTRITION 肠道失调,人体健康和功能性营养
Q4 Agricultural and Biological Sciences Pub Date : 2017-01-01 DOI: 10.21323/2414-438X-2017-2-4-44-61
I. Chicherin, I. Pogorelsky, I. Lundovskikh, I. V. Darmov, M. R. Shabalina
The interest of scientists, physicians, pediatricians, general practitioners to the problem of intestinal dysbiosis is caused by the fact that there are very close relations between the intestinal microbiocenosis disorders and organic and functional pathology not only of the gastrointestinal tract, but also of other organs. For more than 50 years probiotics have been the leading tool for correction of intestinal microbiocenosis. However, the response of intestinal microbiota to exogenous intake of probiotics is variable, or is completely absent. The article presents the analysis of the literature data and results of our own experimental studies on human volunteers, fully confirming previous findings on laboratory animals, according to which the probiotic microorganisms are foreign and do not survive in the gastrointestinal tract of humans and animals, and their interaction with the host organism has the character of «host against probiotic». The results of the comparative study on the effectiveness of 18 modern preparations for correction of intestinal microbiocenosis at antibiotic-associated dysbiosis in experiments on animals are given. The comparative experimental research on the effectiveness of modern preparations that are frequently used in clinical practice as well as recent innovative commercial and experimental preparations (Actoflor-C. Stimbifid plus, Stimex) regarding intestinal microbiota recovery at antibioticassociated dysbiosis in conventional white mice was carried out. IgorYu. Chicherin1, Ivan P. Pogorelsky2, Irina A. Lundovskikh2, IlyaV. Darmov2, Marina R. Shabalina2 1 Scientific society «Microbiota», Sergiev Posad, Moscow Region, Russia 2 Vyatka State University, Kirov, Russia УДК/UDC 621.3 DOI 10.21323/2414–438X-2017–2–4-44-61 Для цитирования: Чичерин и.Ю., Погорельский и.П., лундовских и.а., Дармов и.в., Шабалина М.р. Дисбиоз кишечника, здоровье человека и функциональное питание. Теория и практика переработки мяса. 2017; 2(4):44-61. DOI:10.21323/2414– 438X-2017–2–4–44-61 FOr cItatIOn: chicherin I.Yu., Pogorelsky I.P., Lundovskikh I.a., Darmov I.V., Shabalina M.r. Intestinal dysbiosis, human health and functional nutrition. Theory and practice of meat processing. 2017;2(4):44-61. (In russ.) DOI:10.21323/2414–438X-2017–2–4–44-61 Чичерин И.Ю. 1, Погорельский И.П. 2, Лундовских И.А.2, Дармов И.В.2, Шабалина М.Р.2 1 Научное общество «Микробиота», Сергиев Посад, Московская область, Россия 2 Вятский государственный университет, Киров, Россия
科学家、医生、儿科医生、全科医生对肠道生态失调问题的兴趣是由于肠道微生物病不仅与胃肠道的有机和功能病理有非常密切的关系,而且与其他器官的有机和功能病理也有密切的关系。50多年来,益生菌一直是纠正肠道微生物病的主要工具。然而,肠道菌群对外源性益生菌摄入的反应是可变的,或者完全不存在。本文分析了文献资料和我们自己对人类志愿者的实验研究结果,充分证实了以前在实验动物上的发现,根据益生菌微生物是外来的,在人类和动物的胃肠道中不生存,它们与宿主生物的相互作用具有“宿主对抗益生菌”的特征。本文给出了18种现代制剂在动物实验中纠正抗生素相关生态失调的肠道微生物病的效果的比较研究结果。对临床实践中经常使用的现代制剂以及最近创新的商业和实验制剂(actoflorc)的有效性进行比较实验研究。对常规小白鼠在抗生素相关生态失调时肠道菌群恢复情况进行了Stimbifid + (Stimex)研究。IgorYu。齐杰林1,Ivan P. Pogorelsky2, Irina A. Lundovskikh2, IlyaV。Darmov2, Marina R. shabalin2 1俄罗斯莫斯科地区Sergiev Posad科学学会«Microbiota»2俄罗斯基洛夫维亚特卡国立大学УДК/UDC 621.3 DOI 10.21323/2414-438X-2017-2-4-44-61 Для цитирования: Чичерин и.Ю。, Погорельский и.П。, лундовских и.а。, Дармов и.в。, Шабалина М.р。Дисбиозкишечника,здоровьечеловекаифункциональноепитание。Теория * практика переработки мяса。2017;2(4): 44 - 61。DOI:10.21323/2414 - 438X-2017-2-4-44-61引文来源:chicherin i.u yu。[3],李建军,李建军,李建军。肠道生态失调,人体健康与功能性营养。肉类加工理论与实践。2017; 2(4): 44 - 61。(俄国人)。DOI: 10.21323 / 2414 - 438 x - 2017 - 2 - 4 - 44 - 61ЧичеринИЮ。1、Погорельский И.П。2、Лундовских И.А。2、Дармов И.В。2、Шабалина М.Р。2 1Научноеобщество«Микробиота»,СергиевПосад,Московскаяобласть,Россия2Вятскийгосударственныйуниверситет,Киров,Россия
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引用次数: 0
ИССЛЕДОВАНИЕ ЦВЕТОВЫХ ХАРАКТЕРИСТИК МЫШЕЧНОЙ И ЖИРОВОЙ ТКАНЕЙ И МРАМОРНОСТИ ГОВЯДИНЫ 研究肌肉和脂肪组织和牛肉大理石的颜色特征
Q4 Agricultural and Biological Sciences Pub Date : 2016-12-22 DOI: 10.21323/2414-438X-2016-1-4-51-56
A. B. Lisitsyn, I. V. Kozyrev
The studies of meat and fat colour and marbling in Longissimus dorsi of different cattle — beef-producing (Aberdeen-Angus,Herefordbreeds) and dual-purpose (Simmental, Black-and-white breeds) — allowed to define groups by the colour values according to Lab international colour model. Measurements were performed 24 hours post-mortem between 12th and 13th ribs. It was found that different ranges of meat colour differed primarily in L* (lightness) and a* (redness) values, while b* (yellowness) values did not significantly differ. The highest differentiation between ranges of fat colour was noted in b* values, whereas L* and a* slightly differed. Moreover, visual assessment of beef marbling by four grades (small, moderate, good, and rich) and instrumental (microstructural) analysis using a computer image analysis system were carried out. The morphometric study of marbling was conducted in accordance with the principles of system quantitative analysis. To perform quantitative measurements, object analysis parameters (area) were specified. Both automatic and manual measurements of specified parameters were used. The study of Longissimus dorsi marbling established high agreement between visual and instrumental evaluations of marbling.
通过对不同牛背最长肌的肉和脂肪颜色和大理石花纹的研究——产牛肉牛(阿伯丁-安格斯品种,赫里福德品种)和两用牛(西蒙塔尔品种,黑白品种)——可以根据Lab国际颜色模型的颜色值来定义群体。测量是在死后24小时在第12和第13根肋骨之间进行的。不同范围肉色的差异主要表现在L*(明度)和a*(红度)值上,而b*(黄度)值差异不显著。脂肪颜色范围之间的差异最大的是b*值,而L*和a*略有不同。此外,利用计算机图像分析系统对牛肉大理石花纹进行了四个等级(小、中、好、丰富)的视觉评价和仪器(显微结构)分析。按照系统定量分析的原则,对大理石纹进行了形态计量学研究。为了进行定量测量,指定了对象分析参数(区域)。采用了自动和手动测量指定参数的方法。背最长肌大理石纹的研究建立了视觉和仪器对大理石纹的高度一致评价。
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引用次数: 2
Риски и безопасность использования нанотехнологий пищевых продуктов: обзор 纳米食品技术的风险和安全:概述
Q4 Agricultural and Biological Sciences Pub Date : 2016-10-24 DOI: 10.21323/2414-438X-2016-1-3-35-47
N. Gorbunova, E. K. Tunieva
The problem of healthy and quality nutrition has a global character. The modern development of technologies including nanotechnologies allowed obtaining materials with unique properties, which began to be actively used in food industry and agriculture but, at the same time, require thorough investigation of their properties and effects on the human body and environment. The paper demonstrates the main directions of the nanotechnology use in the agricultural production and food industry, examines the safety problems and risks occurred when using nanotechnologies in food industry with account for insufficient research on the influence of food nanotechnologies on human health and environmental ecology, and presents the normative and methodical base of the Russian Federation for assurance of safe consumption of food products produced from nanomaterials.
健康和优质营养问题具有全球性。包括纳米技术在内的现代技术的发展使得获得具有独特性能的材料成为可能,这些材料开始在食品工业和农业中得到积极应用,但与此同时,需要对其性能以及对人体和环境的影响进行彻底的研究。该文件说明了纳米技术在农业生产和食品工业中应用的主要方向,考虑到对食品纳米技术对人类健康和环境生态影响的研究不足,审查了在食品工业中使用纳米技术时出现的安全问题和风险,并介绍了俄罗斯联邦确保用纳米材料生产的食品安全消费的规范和系统基础。
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引用次数: 1
IDENTIFICATION OF THE MICROBIOLOGICAL RISKS OF CONTAMINATION OF CATTLE AND PIG CARCASSES WITH PATHOGENS AT SLAUGHTER AND PROCESSING 鉴定屠宰和加工过程中被病原体污染的牛和猪尸体的微生物风险
Q4 Agricultural and Biological Sciences Pub Date : 2016-07-08 DOI: 10.21323/2414-438x-2016-1-2-34-41
D. Bataeva, Y. Yushina, E. Zaiko
In this work, the risk of contamination of cattle and pig carcasses with pathogens at different stages of their slaughter and processing was assessed. The analysis of meat (carcasses, half carcasses and cuts) and meat semi-prepared products from beef and pork for the presence of the microorganisms of the genera Salmonella and Listeria, and Listeria monocytogenes in the samples taken by the destructive (from the depth) and nondestructive (from the surface) methods was carried out to determine the critical points. It was found that the deep layers of beef and pork cuts were not contaminated with the microorganisms of the genus Salmonella and L.monocytogenes. However, surface contamination of cattle and pig carcasses and half-carcasses with Salmonella and L.monocytogenes was revealed at the stages of hide removal and evisceration of the carcasses. Dry and wet cleaning of carcasses and half-carcasses did not facilitate the reduction of contamination. This fact is the cause of contamination of meat semi-prepared products (small-sized and minced), which was established during the study.
在这项工作中,对牛和猪尸体在屠宰和加工的不同阶段被病原体污染的风险进行了评估。采用破坏性(深层)法和非破坏性(表面)法对牛肉和猪肉的肉(胴体、半胴体和切块)和肉类半成品中沙门氏菌、李斯特菌和单核增生李斯特菌的存在进行了分析,以确定临界点。结果表明,牛肉和猪肉切块的深层未受沙门氏菌和单核细胞增生杆菌的污染。然而,牛和猪的胴体和半胴体的表面被沙门氏菌和单核增生李斯特菌污染是在去皮和去内脏阶段发现的。干湿清洗胴体和半胴体并不能减少污染。这一事实是在研究中确定的肉类半成品(小尺寸和切碎的)污染的原因。
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引用次数: 2
PREDICTION OF MEAT PRODUCT QUALITY BY THE MATHEMATICAL PROGRAMMING METHODS 用数学规划方法预测肉制品质量
Q4 Agricultural and Biological Sciences Pub Date : 2016-06-04 DOI: 10.21323/2414-438x-2016-1-1-75-90
A. Lisitsyn, M. Nikitina, A. Zakharov, E. B. Sus, V. Nasonova, L. I. Lebedeva
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引用次数: 6
ANTE-MORTEM FORMATION OF THE QUALITATIVE CHARACTERISTICS OF ENVIRONMENTALLY FRIENDLY MEAT RAW MATERIAL BY INTENSIFICATION OF THE MECHANISMS OF THE METABOLIC PROCESSES IN GILTS 通过强化后备母猪代谢过程的机制,在宰前形成环境友好型肉类原料的质量特征
Q4 Agricultural and Biological Sciences Pub Date : 2016-06-04 DOI: 10.21323/2114-441X-2016-1-32-45
T. M. Giro, Zh. G. Egorova, V. Avdeenko, A. Molchanov
Abstract In order to reduce the time of feeding, increase the intensity of weight gain without hormones, antibiotics, anabolic drugs, as well as to obtain high-quality meat with marble structure, the authors studied the influence of ovarioectomy on the intensification of the metabolic processes in gilts. The experiments were carried out in the FGUP “Mummovskoe” – the educational experimental enterprise of the Russian State Agrarian University - Moscow Timiryazev Agricultural Academy (RSAU – MAA named after K.A.  Timiryazev), in the Atkarsky district of the Saratov region. Two groups of Duroc gilts (10 animals each) raised under the same conditions were studied. As a result of the experiment, the influence of ovariectomy on the level of insulinlike growth factor-1 (IGF-1) and indicators of metabolic processes in gilts were established. It is confirmed that stimulation of the the somatotropin/insulin-like growth factor (ST-IGF) system along with hereditary factors and the characteristics of feeding contributes to the development of muscle tissue. Stimulation of ST secretion with insulin-like growth factor facilitates the development of muscle tissue. An increase in IGF-1 level leads to the development of new muscle fibers and muscle hyperplasia. After surgery, the major factors of changes in meat and feeding indicators in gilts were the rise in the metabolic activity of muscle tissue and fat metabolism, enhancement of production of IGF-1, which has insulin-like action and ensures activation of the processes of cell proliferation and differentiation. Increase in IGF-1 level had a positive impact on meat productivity, chemical and biochemical composition of pork. Simultaneous triggering of the systemic catabolic and local anabolic reactions in gilts after ovariectomy contributed to obtaining higher nutritional value of meat.
摘要为了在不使用激素、抗生素和合成代谢药物的情况下缩短饲喂时间,增加增重强度,获得大理石结构的优质肉质,作者研究了卵巢切除对母猪代谢过程增强的影响。这些实验是在位于萨拉托夫地区阿特卡尔斯基区的FGUP“Mummovskoe”进行的,这是俄罗斯国立农业大学的教育实验企业-莫斯科Timiryazev农业学院(RSAU - MAA以K.A. Timiryazev命名)。研究了在相同条件下饲养的两组杜洛克小母猪(每组10只)。本试验旨在探讨卵巢切除对后备母猪胰岛素样生长因子-1 (IGF-1)水平及代谢过程指标的影响。研究证实,促生长激素/胰岛素样生长因子(ST-IGF)系统的刺激、遗传因素和饲养特性对肌肉组织的发育有促进作用。胰岛素样生长因子刺激ST分泌促进肌肉组织发育。IGF-1水平升高导致新肌纤维的形成和肌肉增生。手术后,后备母猪肉质和饲养指标变化的主要因素是肌肉组织代谢活性和脂肪代谢的升高,IGF-1的产生增强,IGF-1具有胰岛素样作用,确保细胞增殖和分化过程的激活。IGF-1水平的升高对肉品产量、猪肉化学生化成分均有积极影响。卵巢切除后的后备母猪同时触发全身分解代谢和局部合成代谢反应,有助于获得更高的肉营养价值。
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引用次数: 2
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Teoria i Praktika Pererabotki Masa
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