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Dietary Intake, Nutritional Status, and Quality of Life in Patients with Thalassemia Major 重度地中海贫血患者的饮食摄入、营养状况和生活质量
Pub Date : 2022-06-01 DOI: 10.15850/amj.v9n2.2301
Steven Yulius Usman, Salvabilla Azheema Rahmat, Vetinly, Felicia Kurniawan
Background: Impaired growth and inadequacy of dietary intake in thalassemia patients may affect the quality of life. This study aimed to determine and examine the relationship between dietary intake, nutritional status, and quality of life in in patients with thalassemia major. Methods: This study was a cross-sectional descriptive study conducted from February to October 2020. Twelve respondents who were registered at the Yayasan Thalassemia Indonesia and the blood transfusion unit at Fatmawati Hospital participated. This study conducted a physical examination and distributed food record questionnaires and WHOQOL-BREF. Data analysis was performed using Nutrisurvey 2007 and Fisher’s exact test. Results: The majority of the respondent were male (58.3%), categorized in the age group 5–18 years (58.3%), had normal nutritional status (50%) and quality of life. Interestingly, the respondents had an excess intake of protein and fats, while the intake of energy and carbohydrates was normal. Respondents had less intakes of all micronutrients. Conclusion: The majority of respondents have normal nutritional status and quality of life but have a low intake of micronutrients. Both patients and parents need to be further educated on dietary intake to meet their nutritional needs
背景:地中海贫血患者生长发育障碍和饮食摄入不足可能影响生活质量。本研究旨在确定和检查重型地中海贫血患者的饮食摄入、营养状况和生活质量之间的关系。方法:本研究为横断面描述性研究,于2020年2月至10月进行。在Yayasan Thalassemia Indonesia和Fatmawati医院输血室登记的12名受访者参与了调查。本研究进行了身体检查,并分发了食物记录问卷和WHOQOL-BREF。使用Nutrisurvey 2007和Fisher精确测试进行数据分析。结果:大多数受访者为男性(58.3%),年龄组为5-18岁(58.3%,营养状况正常(50%),生活质量良好。有趣的是,受访者摄入了过量的蛋白质和脂肪,而摄入的能量和碳水化合物是正常的。受访者摄入的所有微量营养素较少。结论:大多数受访者营养状况和生活质量正常,但微量营养素摄入量较低。患者和父母都需要进一步接受饮食摄入方面的教育,以满足他们的营养需求
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引用次数: 1
Impact of Instagram Usage Intensity on Self-Esteem among Preclinical Medical Students Instagram使用强度对临床前医学生自尊的影响
Pub Date : 2022-06-01 DOI: 10.15850/amj.v9n2.2307
Maria Christina Sekarlangit, D. Ridjab, Eva Suryani, Dwi Jani Juliawati
Background: Instagram is one of the social media that is growing rapidly in Indonesia. However, the impact of Instagram usage intensity, especially on the users’ emotional well-being, is still unclear. This study aimed to explore the impact of the intensity of using Instagram on the self-esteem among preclinical medical students in Jakarta. Methods: This study was an observational analytic study with a cross-sectional approach in preclinical medical students in Jakarta, Indonesia, conducted from January 2020 to January 2021. Sampling was performed by stratified random sampling followed by simple random sampling. Instagram usage intensity and self-esteem were measured using the Instagram Intensity Scale Questionnaire (IISQ) and the Rosenberg Self-Esteem Scale (RSES). Data were analyzed using the Chi-Square test. Results: Of the108 students, 45.4% had used Instagram above the usage intensity average (average 3.01), of whom 30.6% had low self-esteem (15 out of 49). There was a significant relationship between Instagram usage intensity and self-esteem (p=0.031). Conclusion: Instagram usage intensity has an impact on the self-esteem of preclinical medical students. Further studies are needed to explore this issue, as to see other contributing factors and a larger population with different characteristics.
背景:Instagram是印尼发展迅速的社交媒体之一。然而,Instagram使用强度的影响,尤其是对用户情绪健康的影响,仍不清楚。本研究旨在探讨使用Instagram的强度对雅加达临床前医学生自尊的影响。方法:本研究是一项观察性分析研究,采用横断面方法,于2020年1月至2021年1月在印度尼西亚雅加达的临床前医学生中进行。抽样采用分层随机抽样和简单随机抽样。使用Instagram强度量表(IISQ)和Rosenberg自尊量表(RSES)测量Instagram使用强度和自尊。数据采用卡方检验进行分析。结果:在108名学生中,45.4%的学生使用Instagram的强度高于平均水平(平均3.01),其中30.6%的学生自卑(49人中有15人)。Instagram使用强度与自尊之间存在显著关系(p=0.031)。需要进一步的研究来探索这个问题,以了解其他促成因素和具有不同特征的更大人群。
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引用次数: 0
Aspartate Aminotransferase to Platelet Ratio Index Score in Correlation with Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio to Predict Hepatic Cirrhosis in Hepatitis C Patients 天门冬氨酸转氨酶与血小板比值指数评分与中性粒细胞与淋巴细胞比值及血小板与淋巴细胞比值预测丙型肝炎肝硬化的相关性
Pub Date : 2022-06-01 DOI: 10.15850/amj.v9n2.2553
Jane Haryanto, A. Indrati, Tiene Rostini
Background: Tissue biopsy examination which is an invasive procedure has become the mainstay for hepatic cirrhosis identification in patients with hepatitis. Alternatively, noninvasive method using the aspartate aminotransferase (AST) to platelet ratio index (APRI) score has been developed to predict hepatic cirrhosis. Furthermore, the neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) have been used to predict the severity of hepatitis C. This study aimed to analyze the relationship between APRI scores and NLR and PLR in chronic hepatitis C patients. Methods: This correlative cross-sectional observational study used secondary data of complete blood counts such as neutrophil, lymphocyte, and platelet values, as well as AST values of patients with hepatitis C in the outpatient and inpatient installation of Dr. Hasan Sadikin General Hospital during 2019. The inclusion criteria were patients aged ≥18 years, male and female, who were diagnosed as hepatitis C patients, patients who had AST examination data, leukocytes, count type, and platelets. Data were analyzed using the Spearman rank correlation test. Results: The 123 subjects were dominantly male with an age range of 46–55 years. There was no correlation between the APRI and NLR scores (p=0.229). However, there was a moderate and significant negative correlation between APRI and PLR scores with a correlation coefficient of -0.468 (p=0.000). Conclusion: There is a significant negative correlation between APRI and PLR scores to predict the occurrence of hepatic cirrhosis in patients with Hepatitis C.
背景:组织活检是一种侵入性检查,已成为肝炎患者肝硬化诊断的主要手段。另外,利用天冬氨酸转氨酶(AST)与血小板比值指数(APRI)评分的无创方法也被用于预测肝硬化。此外,中性粒细胞淋巴细胞比率(NLR)和血小板淋巴细胞比率(PLR)已被用于预测丙型肝炎的严重程度。本研究旨在分析慢性丙型肝炎患者APRI评分与NLR和PLR的关系。方法:本相关横断面观察研究采用哈桑·萨迪金综合医院2019年门诊和住院丙型肝炎患者全血细胞计数(如中性粒细胞、淋巴细胞、血小板值)和AST值的二次数据。纳入标准:年龄≥18岁,确诊为丙型肝炎的患者,男性和女性,有AST检查资料的患者,白细胞、计数类型和血小板。数据分析采用Spearman秩相关检验。结果:123例受试者以男性为主,年龄在46 ~ 55岁之间。APRI与NLR评分无相关性(p=0.229)。而APRI与PLR评分呈中度显著负相关,相关系数为-0.468 (p=0.000)。结论:APRI与PLR评分在预测丙型肝炎患者肝硬化发生方面存在显著负相关。
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引用次数: 0
Prevalence of Opportunistic Infection in Central Nervous System among Patients with HIV/AIDS at Dr. Hasan Sadikin General Hospital Bandung, Indonesia 印度尼西亚万隆Hasan Sadikin综合医院HIV/AIDS患者中枢神经系统机会性感染的患病率
Pub Date : 2022-06-01 DOI: 10.15850/amj.v9n2.2298
Dinda Sayyidah Laela Fatimatuzzahra, A. Ganiem, A. Cahyani, Suryani Gunadharma, S. Dian
Background: The low coverage of diagnosis and treatment in patients with human immunodeficiency virus (HIV) infection in Indonesia increases the risk of opportunistic infections that affects various organs, including the central nervous system (CNS). This study aimed to determine the prevalence of opportunistic infections in the CNS among hospitalized patients with HIV/acquired immune deficiency syndrome (AIDS) at Dr. Hasan Sadikin General Hospital Bandung, Indonesia. Methods: In this cross-sectional study with a total sampling method, data were collected from HIV/AIDS patients who were diagnosed with CNS opportunistic infection and hospitalized in the neurology ward during the period 2015–2019. Data were presented as median (interquartile range) and percentage frequency. Results: Among the 2,606 HIV/AIDS patients registered, 219 (8.4%) were accompanied by CNS opportunistic infections. The highest number was cerebral toxoplasmosis (58.9%; n=129) followed by tuberculous meningitis (33.3%; n=73) and cryptococcal meningitis (7.8%; n=17). Most of the patients admitted for unconsciousness (64.4%; n=141), with unknown HIV-infection status (61.2%; n=134). Among patients with positive HIV-infection status, only 50.6% (43/85) patients were taking antiretroviral therapy (ART) and 24.7% (21/85) patients dropped out ART before being diagnosed with CNS opportunistic infections. The CD4+’s median value was 21 cells/mm3 (IQR 9-61.25), with mortality during hospitalization was 36.5% (80/219). Conclusions: The prevalence of CNS opportunistic infections among HIV-infected patients is 8.4%, dominated by cerebral toxoplasmosis, and laboratory result showed very low CD4+ levels. The diagnosis of HIV infection is shortly made before hospitalization, and those who has been diagnosed have low compliance with ART. The mortality rate during hospitalization is high.
背景:印度尼西亚人类免疫缺陷病毒(HIV)感染患者的诊断和治疗覆盖率低,增加了影响各种器官的机会性感染的风险,包括中枢神经系统(CNS)。本研究旨在确定印度尼西亚万隆哈桑·萨迪金医生总医院的艾滋病毒/获得性免疫缺陷综合征(艾滋病)住院患者中中枢神经系统机会性感染的患病率。方法:采用全抽样的横断面研究方法,收集2015-2019年神经内科病房确诊为中枢神经系统机会性感染的HIV/AIDS患者的数据。数据以中位数(四分位数范围)和百分比频率表示。结果:2606例HIV/AIDS患者中,219例(8.4%)伴有中枢神经系统机会性感染。以脑弓形体病最多(58.9%);129例),其次是结核性脑膜炎(33.3%;73例)和隐球菌脑膜炎(7.8%;n = 17)。以意识不清为主(64.4%);n=141), hiv感染状况未知(61.2%;n = 134)。在hiv感染阳性的患者中,只有50.6%(43/85)的患者正在接受抗逆转录病毒治疗(ART), 24.7%(21/85)的患者在被诊断为中枢神经系统机会性感染之前退出了抗逆转录病毒治疗。CD4+中位值为21个细胞/mm3 (IQR 9-61.25),住院期间死亡率为36.5%(80/219)。结论:hiv感染者中枢神经系统机会性感染发生率为8.4%,以脑弓形体病为主,实验室检测CD4+水平极低。艾滋病毒感染的诊断是在住院前不久做出的,而那些被诊断出感染的人对抗逆转录病毒治疗的依从性很低。住院期间的死亡率很高。
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引用次数: 0
Knowledge, Attitude, and Perception about Autopsy among Community in Bandung 万隆社区尸检的知识、态度和认知
Pub Date : 2022-06-01 DOI: 10.15850/amj.v9n2.2539
Aisyah Putri Pratiwi, B. I. Fitrasanti, S. Tanzilah
Background: Autopsy is a comprehensive evaluation of the body and the circumstances surrounding an individual’s death. Currently, autopsy rates in various countries have been decreased in recent years. This decrease was due to the rejection by people who had inadequate knowledge, attitudes, and perceptions about autopsies. This study aimed to determine the knowledge, attitudes, and perceptions of Bandung residents about autopsies. Methods: This cross-sectional descriptive observational study involved people in the Bandung City who were over the age of 20 during the period August to September 2020. The sample was obtained using a snowball system. Research subjects filled out a questionnaire through a Google form containing questions about knowledge, attitudes, and perceptions. The results were categorized based on the median for each variable. Results: Subjects with questionnaire data obtained were 378 people with an average age of 30.30±13.48 years, and most (66.9%) were female. A total of 259 people had adequate knowledge (68.5%), 254 people (67.2%) had a positive attitude, and 249 people (65.9%) had a positive perception, with a median value of 7, 6, and 12, respectively. However, 95 people did not agree to do an autopsy on their relatives or family to determine the cause of death. Conclusion: The subject as a whole showed adequate knowledge, positive attitude, and perception. However, there are still some people who show inadequate knowledge and poor attitudes and perceptions about autopsies. It is recommended that the government and other institutions intervene in the community to increase knowledge and attitudes and improve public perception.
背景:尸体解剖是对尸体和个人死亡情况的综合评估。目前,近年来各国的尸体解剖率有所下降。这种减少是由于那些对尸体解剖缺乏足够的知识、态度和看法的人的拒绝。本研究旨在了解万隆居民对尸体解剖的认识、态度和看法。方法:这项横断面描述性观察研究涉及2020年8月至9月期间万隆市20岁以上的人群。样品是用滚雪球法获得的。研究对象通过谷歌表格填写了一份调查问卷,其中包含有关知识、态度和看法的问题。结果根据每个变量的中位数进行分类。结果:获得问卷资料的受试者378人,平均年龄30.30±13.48岁,以女性居多(66.9%)。共有259人(68.5%)有足够的知识,254人(67.2%)有积极的态度,249人(65.9%)有积极的看法,中位数分别为7、6、12。然而,95人不同意对他们的亲属或家人进行尸检以确定死亡原因。结论:受试者总体上表现出充分的知识、积极的态度和感知。然而,仍然有一些人对尸体解剖的认识不足,态度和观念不佳。建议政府和其他机构在社区进行干预,以增加知识和态度,并改善公众的看法。
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引用次数: 0
Knowledge and Attitudes towards Premarital Screening among Adolescents: A study in a University Setting 青少年对婚前筛查的知识和态度:一项在大学环境中的研究
Pub Date : 2022-06-01 DOI: 10.15850/amj.v9n2.2502
Annisa Triska Almanda Dewi, A. Susanti, F. Rinawan, Sharon Gondodiputro, Neneng Martini
Background: Premarital screening (PMS) is an action to prevent the occurrence of genetic and the transmission of infectious diseases. The screening has been recommended and promoted in Indonesia. This study aimed to assess the level of knowledge and attitudes towards premarital screening among teenagers in a university setting. Methods: This study used a cross-sectional design, including 310 adolescents aged 18–21 years at obtained through a non-random consecutive sampling at Universitas Padjadjaran. The data was collected from October 2020 until January 2021 using a close-ended questionnaire, assessing knowledge and attitude towards the PMS. The frequency knowledge level was grouped as good, moderate, and poor. The attitude level was categorized as positive and negative. Results: Most of the respondents (90.3%) had good knowledge of PMS. Respondents who had positive attitudes (79%) strong agreed that carrying out PMS was important, and 51% perceived that PMS needed to be a mandatory procedure before marriage. However, 59.6% had no idea how to deal if the result of the PMS was positive. Conclusion: In general, adolescents at Universitas Padjadjaran have good knowledge and a positive attitude towards PMS. However, comprehensive information about PMS is still needed, especially on decision points that must be taken after getting the test results.
背景:婚前筛查(PMS)是预防遗传性疾病发生和传染病传播的一项行动。该筛查已在印度尼西亚得到推荐和推广。本研究旨在评估大学环境中青少年对婚前筛查的知识和态度水平。方法:本研究采用横断面设计,包括310名18-21岁的青少年,他们是通过帕贾贾兰大学的非随机连续抽样获得的。数据收集于2020年10月至2021年1月,使用封闭式问卷,评估对经前综合症的知识和态度。频率知识水平分为良好、中等和较差。态度水平分为积极和消极两类。结果:绝大多数(90.3%)被调查者对经前综合症有较好的了解。持积极态度的受访者(79%)强烈认为进行经前综合症很重要,51%的人认为经前综合症需要成为婚前的强制性程序。然而,59.6%的人不知道如何处理经前综合症的结果是否为阳性。结论:Padjadjaran大学的青少年对经前综合症有良好的认识和积极的态度。然而,仍然需要关于PMS的全面信息,特别是在得到测试结果后必须采取的决策点。
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引用次数: 0
Hearing Profile of Children Below Three Years Old at Jatinangor Integrative Health Care Center, West Java, Indonesia 印度尼西亚西爪哇Jatinangor综合保健中心三岁以下儿童的听力概况
Pub Date : 2022-06-01 DOI: 10.15850/amj.v9n2.2525
Fidkya Allisha, Wijana, Sally Mahdiani
Background: Hearing function is one of the most important factors affecting children’s development process. The first three years of life is a golden period of growth and development of children. This study was conducted to investigate the hearing profile of children below three years old at Jatinangor Integrative Health Care Center (Pos Pelayanan Terpadu, Posyandu), West Java, Indonesia. Methods: An observational cross-sectional study was conducted to 86 children below three years old who was selected by using multistage cluster sampling at 12 Posyandu in Jatinangor sub-district by using in-depth interview related to hearing loss risk factors, reaction test, and tympanometry test. Results: The hearing loss prevalence of children below three years old in the Jatinangor sub-district was 7.0%. Of the 86 children, there were 2.3% (n=2) children with moderate conductive hearing loss, 1.2% (n=1) children with moderate sensorineural hearing loss, and 3.5% (n=3) children with very severe sensorineural hearing loss. Fifty percent of children with sensorineural hearing loss were discovered without any risk factor. Conclusions: The prevalence of hearing loss in children under three years old at the Jatinangor Integrative Health Care Center is slightly higher than the national prevalence. Fifty percent of children are found without risk factors, therefore Universal Newborn Hearing Examination (UNHS) needs to be implemented at the national level in accordance with the guidelines of the Joint Committee for Infant Hearing (JCIH) in which are integrated with primary health care units, tertiary health care centers otorhinolaryngology, and also the audiological center.
背景:听觉功能是影响儿童发育过程的重要因素之一。生命的前三年是孩子成长和发展的黄金时期。本研究旨在调查印度尼西亚西爪哇Jatinangor综合医疗保健中心(Pos Pelayanan Terpadu,Posyandu)三岁以下儿童的听力状况。方法:采用多阶段整群抽样的方法,对Jatinangor街道12 Posyandu的86名3岁以下儿童进行观察性横断面研究,采用与听力损失危险因素相关的深度访谈、反应测试和鼓室测量测试。结果:Jatinangor街道3岁以下儿童的听力损失发生率为7.0%。在86名儿童中,有2.3%(n=2)儿童患有中度传导性听力损失,1.2%(n=1)儿童患有轻度感音神经性听力损失,3.5%(n=3)儿童患有极重度感音神经型听力损失。50%的感音神经性听力损失儿童被发现没有任何危险因素。结论:Jatinangor综合保健中心三岁以下儿童听力损失的患病率略高于全国患病率。50%的儿童被发现没有危险因素,因此需要根据婴儿听力联合委员会(JCIH)的指导方针在国家层面实施新生儿听力普遍检查(UNHS),该委员会与初级卫生保健单位、三级卫生保健中心耳鼻喉科和听力学中心相结合。
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引用次数: 0
Trends in Determinants of Birth Interval based on Data from the Indonesian Demographic Health Survey in 2007, 2012, and 2017 基于2007年、2012年和2017年印度尼西亚人口健康调查数据的出生间隔决定因素趋势
Pub Date : 2022-06-01 DOI: 10.15850/amj.v9n2.2643
Nedra Wati Zaly, M. Rahardja, Murtiningsih
Background: Fertility is the main component of population dynamics that determines the population structure of a country. One method to measure fertility is to analyze the birth interval. This study aimed to identify determinants of birth interval based on the Indonesian Demographic and Health Survey (IDHS) data in 2007, 2012, and 2017. Methods: This study design was descriptive using IDHS data from 2007, 2012, and 2017 with a cross-sectional study design. Samples were mothers who gave birth to their last living child in the last five years. Results: In the IDHS 2007, the birth interval at risk (<24 months) was 11.8%, increased in the 2012 IDHS to 12.1%, and decreased in the 2017 IDHS to 9.8%. In the three-period IDHS, the same determinants of the birth interval were discovered, such as the age of the woman, duration of breastfeeding, use of contraception, the status of the child before the last child, mother’s education level, and wealth quintile. However, in 2007, the sex of the child before the last child and the number of surviving children also influenced the birth interval. In 2017 the number of children who were still alive also affected the birth interval. The most dominant factor influencing the occurrence of short birth intervals after controlling for other variables was the survival status of the previous child. Conclusion: The short birth interval is the most prevalent in the 2012 IDHS. Optimal birth interval has the potential to improve maternal, neonatal, and infant health.
背景:生育率是决定一个国家人口结构的人口动态的主要组成部分。衡量生育率的一种方法是分析出生间隔。本研究旨在根据2007年、2012年和2017年印尼人口与健康调查(IDHS)数据确定出生间隔的决定因素。方法:本研究设计采用横断面研究设计,使用2007年、2012年和2017年的IDHS数据进行描述性研究。样本是在过去五年中生下最后一个孩子的母亲。结果:在2007年IDHS中,有风险的出生间隔(<24个月)为11.8%,在2012年IDHS增加到12.1%,在2017年IDHS减少到9.8%,财富五分之一。然而,在2007年,最后一个孩子之前的孩子的性别和幸存孩子的数量也影响了出生间隔。2017年,还活着的儿童数量也影响了出生间隔。在控制了其他变量后,影响短出生间隔发生的最主要因素是前一个孩子的生存状况。结论:在2012年IDHS中,短出生间隔最为普遍。最佳生育间隔有可能改善产妇、新生儿和婴儿的健康。
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引用次数: 0
Level of Knowledge and Attitude towards COVID-19 among High School students in Depok 德波克市高中生对新冠肺炎的知识和态度水平
Pub Date : 2022-06-01 DOI: 10.15850/amj.v9n2.2513
Arnold, Vycke Yunivita Kusumah Dewi, Fifi Veronica
Background: Depok is the city with the largest COVID-19 cases in West Java, Indonesia. The application of health protocol for high school student as the second-largest age group,’s depends on the level of knowledge and attitudes that can be affected by gender. This study aimed to determine the level of knowledge and attitudes based on the gender of high school students towards COVID-19 in Depok. Methods: This study was a cross-sectional analytic study, conducted from June 2020 to June 2021. The data was collected using a Google form application with a validated questionnaire and the research subjects were high school students in Depok. Knowledge of COVID-19 was assessed with 18 questions, true or false questions. Correct answer was assigned 1 point. Points were summed for a total knowledge score of Poor, Moderate, or Good. Attitude was assessed with 6 questions. For each answer given, subjects with a total score of >18 were assessed as a positive attitude. Results: Of a total of 273 respondents, 238 had met the inclusion criteria. Most of the respondents had a moderate level of knowledge (60.5%) and most of the respondents (89%) had a positive attitude towards COVID-19. No significant differences in level of knowledge or attitude between males and females (p>0.05). Conclusions: High school students in Depok have a moderate level of knowledge and have a positive attitude in dealing with COVID-19 which is not influenced by gender. The lack of information regarding the timing of vaccine administration and examination of COVID-19 needs to be a concern for high school students in Depok.
背景:德波克是印度尼西亚西爪哇省COVID-19病例最多的城市。高中生作为第二大年龄组,其健康方案的应用取决于受性别影响的知识水平和态度。本研究旨在确定Depok高中学生对COVID-19的性别知识和态度水平。方法:本研究是一项横断面分析研究,于2020年6月至2021年6月进行。本研究采用谷歌表格申请及有效问卷收集资料,研究对象为德博区高中生。对COVID-19知识的评估包括18个问题,真假问题。正确答案加1分。总分分为差、中、好三个等级。态度通过6个问题进行评估。对于给出的每个答案,总得分为bbbb18的受试者被评估为积极态度。结果:273名被调查者中,238人符合纳入标准。大多数受访者(60.5%)对新冠肺炎有中等程度的了解,大多数受访者(89%)对新冠肺炎持积极态度。在知识水平和态度上,男女差异无统计学意义(p < 0.05)。结论:Depok高中生对COVID-19的知识水平中等,态度积极,不受性别影响。缺乏有关疫苗接种时间和COVID-19检查的信息需要引起Depok高中学生的关注。
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引用次数: 0
Lung Abnormalities in Systemic Sclerosis Patients through Spirometry, Chest X-Ray, and High-Resolution Computed Tomography Scan 肺活量测定、胸部x线和高分辨率计算机断层扫描对系统性硬化症患者肺部异常的影响
Pub Date : 2022-03-01 DOI: 10.15850/10.15850/amj.v9n1.2509
S. Dewi, Waliyyuddin Robbani, I. D. Kulsum
Background: Systemic sclerosis (SSc) is a multisystem autoimmune illness with a wide range of clinical symptoms. The pulmonary organ manifestations frequently occur, but the symptoms are non-specific. Radiological examination and pulmonary function tests (spirometry) are needed to detect lung abnormalities in SSc patients. This study aimed to obtain information about the overview of lung abnormalities in SSc patients through spirometry, chest x-ray, and high-resolution computed tomography (HRCT) scan examination. Methods: A descriptive qualitative study was conducted on 75 SSc patients registered in Dr. Hasan Sadikin General Hospital Bandung from January 2019 to December 2020. Data were collected with a total sampling method and presented in proportions and percentages. Results: The majority of subjects were affected by cutaneous 73 (97%), pulmonary 29 (39%), and musculoskeletal 17 (23%) involvement. Spirometry revealed that 43 subjects (57%) had restrictive lung disease, with one false-positive case and two false-negative cases. On a chest x-ray, 45 (60%) of subjects had abnormalities. The majority of subjects were found to have Ground-glass opacities on HRCT scans. Ground-glass opacities were discovered in 46 subjects (82%) and 27 subjects (60%) were identified as having severe fibrosis scores. Conclusion: According to spirometry results and abnormalities on chest x-ray and HRCT scans, the majority of SSc patients have restrictive lung disease.
背景:系统性硬化症(SSc)是一种多系统自身免疫性疾病,具有广泛的临床症状。肺器官表现经常发生,但症状无特异性。需要影像学检查和肺功能检查(肺活量测定法)来发现SSc患者的肺部异常。本研究旨在通过肺活量测定、胸部x线和高分辨率计算机断层扫描(HRCT)检查,了解SSc患者肺部异常的概况。方法:对2019年1月至2020年12月在万隆哈桑·萨迪金医生总医院登记的75例SSc患者进行描述性定性研究。数据采用全抽样方法收集,并以比例和百分比表示。结果:大多数受试者受皮肤73例(97%)、肺部29例(39%)和肌肉骨骼17例(23%)受累。肺活量测定显示43名受试者(57%)患有限制性肺部疾病,其中1例假阳性,2例假阴性。在胸部x光片上,45%(60%)的受试者有异常。大多数受试者在HRCT扫描中发现有磨玻璃样混浊。46例(82%)患者发现毛玻璃样混浊,27例(60%)患者被确定为重度纤维化评分。结论:根据肺活量测定结果及胸部x线及HRCT扫描异常,大多数SSc患者为限制性肺疾病。
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引用次数: 0
期刊
Althea Medical Journal
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