Background: Platelet-rich plasma (PRP) is a new concept used in medical world, especially for wound healing. The main process that affects the PRP quality is the centrifugation process. This study aimed to assess the PRP separation process and determine the best technique of various centrifugation process.Methods: This experimental study used acid citrate dextrose (ACD) blood taken from 11 healthy respondents and compared three-techniques including the single centrifugation (SC), the double centrifugation (DC), and the double centrifugation turn down - turn up (DC-TDTU) techniques. The quality of PRP was measured based on blood cells count (platelet, leukocyte, erythrocyte count, and Ht value) at each stage of centrifugation. The examination was carried out in 2021 at the Hematology Laboratory, Poltekkes Jakarta 3.Results: The mean values of platelets, leukocytes, and Ht were increased in PRP compared to plasma supernatant both using the DC and DC-TDTU techniques, wherase the SC technique decreased in plasma compared with whole blood. When the procedures using DC and DC-TDTU are carried out properly, platelets would be concentrated in the second centrifugation. However, some erythrocyte and leukocyte contamination occurred by DC-TDTU technique compared to the DC technique.Conclusion: The double centrifugation technique is the best Platelet-rich plasma separation technique compared to the DC-TDTU and SC techniques.
背景：富含血小板的血浆（PRP）是医学界使用的一个新概念，尤其是用于伤口愈合。影响PRP质量的主要过程是离心过程。本研究旨在评估PRP分离过程，并确定各种离心过程的最佳技术。方法：本实验采用11名健康受试者的酸性柠檬酸-葡萄糖（ACD）血液，比较了单次离心（SC）、双次离心（DC）和双次离心下翻（DC-TDTU）三种技术。基于离心每个阶段的血细胞计数（血小板、白细胞、红细胞计数和Ht值）来测量PRP的质量。该检查于2021年在Poltekkes Jakarta 3的血液学实验室进行。结果：与使用DC和DC-TDTU技术的血浆上清液相比，PRP中血小板、白细胞和Ht的平均值增加，而血浆中SC技术的平均值与全血相比降低。当使用DC和DC-TDTU的程序正确进行时，血小板将在第二次离心中浓缩。然而，与DC技术相比，DC-TDTU技术发生了一些红细胞和白细胞污染。结论：与DC-TDTU和SC技术相比，双离心技术是最好的富血小板血浆分离技术。
{"title":"Comparison of Single Centrifugation, Double Centrifugation and Turn down-Turn up Techniques for Platelet-Rich Plasma Quality","authors":"E. A. Maharani, Dewi Astuti","doi":"10.15850/amj.v9n3.2628","DOIUrl":"https://doi.org/10.15850/amj.v9n3.2628","url":null,"abstract":"Background: Platelet-rich plasma (PRP) is a new concept used in medical world, especially for wound healing. The main process that affects the PRP quality is the centrifugation process. This study aimed to assess the PRP separation process and determine the best technique of various centrifugation process.Methods: This experimental study used acid citrate dextrose (ACD) blood taken from 11 healthy respondents and compared three-techniques including the single centrifugation (SC), the double centrifugation (DC), and the double centrifugation turn down - turn up (DC-TDTU) techniques. The quality of PRP was measured based on blood cells count (platelet, leukocyte, erythrocyte count, and Ht value) at each stage of centrifugation. The examination was carried out in 2021 at the Hematology Laboratory, Poltekkes Jakarta 3.Results: The mean values of platelets, leukocytes, and Ht were increased in PRP compared to plasma supernatant both using the DC and DC-TDTU techniques, wherase the SC technique decreased in plasma compared with whole blood. When the procedures using DC and DC-TDTU are carried out properly, platelets would be concentrated in the second centrifugation. However, some erythrocyte and leukocyte contamination occurred by DC-TDTU technique compared to the DC technique.Conclusion: The double centrifugation technique is the best Platelet-rich plasma separation technique compared to the DC-TDTU and SC techniques.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42254307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ananda Pratama Kesumaningtyas Gunawan, A. Ganiem, Siti Aminah, L. Amalia, S. Dian
Background: Tetanus is a disease characterized by painful muscle spasms all over the body, which still becomes an important health issue worldwide, particularly in developing countries due to the high mortality rate. The clinical features also affect the mortality rate of adult tetanus patients. Tetanus severity score (TSS) is a prognostic scoring system developed in Vietnam that uses clinical features to predict the mortality rate in adult tetanus patients. The aim of this study was to describe the clinical features and outcomes of adult tetanus patients using TSS.Methods: A descriptive, cross-sectional study with a total sampling method was conducted between 2015 and 2019. A total of 71 medical records of adult generalized tetanus patients in the Department of Neurology Dr. Hasan Sadikin General Hospital Bandung were collected to analyze the clinical features and outcomes using TSS. Statistical analysis was performed using SPSS software ver. 25.0.Results: Among seventy-one tetanus patients, 62 (87.3%) were male, and the average age was 55.2±11.2 years. More than half of the patients (71%) were having grade III or worse and experienced dysautonomia complications (57.7%). The mortality rate was 38% and those who survived at discharge, 88.64% had TSS score <8, whereas 37.04% who died had TSS score ≥8.Conclusions: Tetanus in Bandung has a high mortality rate. Those who have died have high TSS scores, while the survivors have low TSS scores, suggesting that the TSS is a prospective scoring to predict the mortality rate in patients with tetanus in Indonesia.
{"title":"Clinical Features and Outcomes of Patients with Tetanus at Dr. Hasan Sadikin General Hospital Bandung 2015–2019","authors":"Ananda Pratama Kesumaningtyas Gunawan, A. Ganiem, Siti Aminah, L. Amalia, S. Dian","doi":"10.15850/amj.v9n3.2299","DOIUrl":"https://doi.org/10.15850/amj.v9n3.2299","url":null,"abstract":"Background: Tetanus is a disease characterized by painful muscle spasms all over the body, which still becomes an important health issue worldwide, particularly in developing countries due to the high mortality rate. The clinical features also affect the mortality rate of adult tetanus patients. Tetanus severity score (TSS) is a prognostic scoring system developed in Vietnam that uses clinical features to predict the mortality rate in adult tetanus patients. The aim of this study was to describe the clinical features and outcomes of adult tetanus patients using TSS.Methods: A descriptive, cross-sectional study with a total sampling method was conducted between 2015 and 2019. A total of 71 medical records of adult generalized tetanus patients in the Department of Neurology Dr. Hasan Sadikin General Hospital Bandung were collected to analyze the clinical features and outcomes using TSS. Statistical analysis was performed using SPSS software ver. 25.0.Results: Among seventy-one tetanus patients, 62 (87.3%) were male, and the average age was 55.2±11.2 years. More than half of the patients (71%) were having grade III or worse and experienced dysautonomia complications (57.7%). The mortality rate was 38% and those who survived at discharge, 88.64% had TSS score <8, whereas 37.04% who died had TSS score ≥8.Conclusions: Tetanus in Bandung has a high mortality rate. Those who have died have high TSS scores, while the survivors have low TSS scores, suggesting that the TSS is a prospective scoring to predict the mortality rate in patients with tetanus in Indonesia.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42736142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mareta Tada Kurnia, Iyus Maolana Yusuf, P. Santoso
Background: The prevalence of multidrug-resistant pulmonary tuberculosis (MDR-TB) continues to increase, especially in Indonesia. Thoracic radiography examination plays a role in the TB diagnosis by providing findings of typical lesions in patients. The aim of the study was to determine the thoracic radiography findings in MDR-TB patients.Methods: This was a cross-sectional retrospective descriptive study. This study had explored secondary data from medical records of patients who previously had a clinical diagnosis of MDR-TB and underwent thoracic radiography examinations at the Department of Radiology, Dr. Hasan Sadikin General Hospital, Bandung on July - August 2020 Result: Of 110 data collected, the average age was 37±12.6 years with male patients were predominantly prevalent and 65.5% had large lesions. The most frequent findings of lesions were calcification (94.5%) and fibrosis (90.9%). Other major findings were infiltration (88.2%), consolidation (55.5%), cavity (65.5%), ground-glass opacity (60.9%) while other were found in less than half of the cases such as bronchiectasis (23%), nodule (34.5%), atelectasis (36.4%), lymphadenopathy (34.5%), and others. Interestingly, the miliary pattern was not found.Conclusion: Large lesions, calcification, fibrosis, infiltration, consolidation, cavities, and ground-glass opacities are the main features of the radiographic findings in the majority of MDR-TB patients.
{"title":"Thoracic Radiography Findings of Multi Drug Resistant Tuberculosis at Dr. Hasan Sadikin General Hospital Bandung","authors":"Mareta Tada Kurnia, Iyus Maolana Yusuf, P. Santoso","doi":"10.15850/amj.v9n3.2618","DOIUrl":"https://doi.org/10.15850/amj.v9n3.2618","url":null,"abstract":"Background: The prevalence of multidrug-resistant pulmonary tuberculosis (MDR-TB) continues to increase, especially in Indonesia. Thoracic radiography examination plays a role in the TB diagnosis by providing findings of typical lesions in patients. The aim of the study was to determine the thoracic radiography findings in MDR-TB patients.Methods: This was a cross-sectional retrospective descriptive study. This study had explored secondary data from medical records of patients who previously had a clinical diagnosis of MDR-TB and underwent thoracic radiography examinations at the Department of Radiology, Dr. Hasan Sadikin General Hospital, Bandung on July - August 2020 Result: Of 110 data collected, the average age was 37±12.6 years with male patients were predominantly prevalent and 65.5% had large lesions. The most frequent findings of lesions were calcification (94.5%) and fibrosis (90.9%). Other major findings were infiltration (88.2%), consolidation (55.5%), cavity (65.5%), ground-glass opacity (60.9%) while other were found in less than half of the cases such as bronchiectasis (23%), nodule (34.5%), atelectasis (36.4%), lymphadenopathy (34.5%), and others. Interestingly, the miliary pattern was not found.Conclusion: Large lesions, calcification, fibrosis, infiltration, consolidation, cavities, and ground-glass opacities are the main features of the radiographic findings in the majority of MDR-TB patients.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44521563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Galuhafiar Puratmaja, A. Alam, D. D. Lukmanul Hakim, S. Rahayuningsih, D. A. Gurnida, D. Hilmanto
Background: Chronic kidney disease (CKD) in children has a long-lived impact, such as an increased risk of bacterial infection. Infection may accelerate disease progression, making early detection crucial. Inflammatory markers typically used for bacterial infection are C-Reactive Protein (CRP) and Procalcitonin (PCT). This study aimed to determine the correlation between levels of neutrophil-to-lymphocyte ratio (NLR) and immature-to-total-neutrophil ratio (I/T ratio) to bacterial infection in children with CKD as indicated by the serum levels of CRP and PCT.Methods: Observational analysis with a cross-sectional design was conducted from January 2019 to November 2021 in children from 3 months to 18 years old with CKD and bacterial infection. Retrospective data were obtained from medical records at Dr. Hasan Sadikin General Hospital, Bandung. Correlation analysis was performed (SPSS program) at a 95% confidence level, and results were considered significant if the p-value <0.05.Results: There were 42 children, and 57% were female; with a median age of 13 years (range 1–17 years). Most patients had normal nutritional status (55%) although 40% were malnourished. Correlation analysis between I/T ratio and NLR with PCT was positive, with r=0.284 (p<0.05) and r=0.265 (p<0.05), respectively, whereas there was no significant correlation of I/T ratio (r=0,154; p>0.05) and NLR (r=0,188; p>0.05) to CRP.Conclusions: NLR and I/T ratios have a significant positive correlation with PCT levels but not with CRP levels. NRL and I/T ratios can be considered as alternative markers for diagnosing CKD in children with a bacterial infection.
{"title":"Correlation between Neutrophil-to-Lymphocyte Ratio (NLR) and Immature-to-total Neutrophil (I/T) Ratio to Bacterial Infection among Children with Chronic Kidney Disease","authors":"Galuhafiar Puratmaja, A. Alam, D. D. Lukmanul Hakim, S. Rahayuningsih, D. A. Gurnida, D. Hilmanto","doi":"10.15850/amj.v9n3.2673","DOIUrl":"https://doi.org/10.15850/amj.v9n3.2673","url":null,"abstract":"Background: Chronic kidney disease (CKD) in children has a long-lived impact, such as an increased risk of bacterial infection. Infection may accelerate disease progression, making early detection crucial. Inflammatory markers typically used for bacterial infection are C-Reactive Protein (CRP) and Procalcitonin (PCT). This study aimed to determine the correlation between levels of neutrophil-to-lymphocyte ratio (NLR) and immature-to-total-neutrophil ratio (I/T ratio) to bacterial infection in children with CKD as indicated by the serum levels of CRP and PCT.Methods: Observational analysis with a cross-sectional design was conducted from January 2019 to November 2021 in children from 3 months to 18 years old with CKD and bacterial infection. Retrospective data were obtained from medical records at Dr. Hasan Sadikin General Hospital, Bandung. Correlation analysis was performed (SPSS program) at a 95% confidence level, and results were considered significant if the p-value <0.05.Results: There were 42 children, and 57% were female; with a median age of 13 years (range 1–17 years). Most patients had normal nutritional status (55%) although 40% were malnourished. Correlation analysis between I/T ratio and NLR with PCT was positive, with r=0.284 (p<0.05) and r=0.265 (p<0.05), respectively, whereas there was no significant correlation of I/T ratio (r=0,154; p>0.05) and NLR (r=0,188; p>0.05) to CRP.Conclusions: NLR and I/T ratios have a significant positive correlation with PCT levels but not with CRP levels. NRL and I/T ratios can be considered as alternative markers for diagnosing CKD in children with a bacterial infection.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46492418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Epafroditus Sanjaya Adiguna, W. S. Utami, I. Sutejo, Bagus Hermansyah, Yunita Armiyanti
Background: Water sources used by households are at risk of contamination by soil-transmitted helminths (STH). Hygiene and sanitation have an essential role in the transmission and contamination of STH. The objective of this study was to analyze whether there was an association between hygiene and sanitation factors with STH contamination in household water sources in Jember Regency, East Java Province, Indonesia.Methods: This cross-sectional analytic study was carried out from December 2020 to March 2021, including 46 samples from 23 respondents in Sukowono District and 23 respondents in Sukorambi District, Jember Regency, selected using a purposive sampling technique. Primary data on hygiene and sanitation risk factors were obtained from questionnaire interviews. The STH contamination in household water sources was examined by sedimentation and flotation methods. Data were analyzed using Fisher Exact test.Results: The identification of STH contamination in household water sources using microscope examination found hookworm species contaminated 8.7% (n=4) of water sources. There was a significant association between the type of human sewage disposal with STH contamination in household water sources (p=0.037). There was no association between hygiene and other sanitation factors with STH contamination in household water sources (p>0.05).Conclusions: Human sewage disposal that goes directly to sewers and rivers can cause contamination of water sources by STH. Therefore, it is important to dispose of human waste in septic tanks that comply with health requirements to prevent the transmission of STH to humans through water sources.
{"title":"Hygiene and Sanitation Factors Affecting Contamination of Soil-Transmitted Helminths in Household Water Sources in Jember, Indonesia","authors":"Epafroditus Sanjaya Adiguna, W. S. Utami, I. Sutejo, Bagus Hermansyah, Yunita Armiyanti","doi":"10.15850/amj.v9n3.2587","DOIUrl":"https://doi.org/10.15850/amj.v9n3.2587","url":null,"abstract":"Background: Water sources used by households are at risk of contamination by soil-transmitted helminths (STH). Hygiene and sanitation have an essential role in the transmission and contamination of STH. The objective of this study was to analyze whether there was an association between hygiene and sanitation factors with STH contamination in household water sources in Jember Regency, East Java Province, Indonesia.Methods: This cross-sectional analytic study was carried out from December 2020 to March 2021, including 46 samples from 23 respondents in Sukowono District and 23 respondents in Sukorambi District, Jember Regency, selected using a purposive sampling technique. Primary data on hygiene and sanitation risk factors were obtained from questionnaire interviews. The STH contamination in household water sources was examined by sedimentation and flotation methods. Data were analyzed using Fisher Exact test.Results: The identification of STH contamination in household water sources using microscope examination found hookworm species contaminated 8.7% (n=4) of water sources. There was a significant association between the type of human sewage disposal with STH contamination in household water sources (p=0.037). There was no association between hygiene and other sanitation factors with STH contamination in household water sources (p>0.05).Conclusions: Human sewage disposal that goes directly to sewers and rivers can cause contamination of water sources by STH. Therefore, it is important to dispose of human waste in septic tanks that comply with health requirements to prevent the transmission of STH to humans through water sources.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45876738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Personal hygiene habits need to be practiced since early childhood because they are essential mechanisms in breaking the chain of transmission of various diseases. Important factors that affect children's personal hygiene are parenting style and maternal personal hygiene. This study aimed to determine the relationship between parenting style and maternal personal hygiene with their children’s personal hygiene.Methods: This study was an analytic observational study with a cross-sectional method conducted in July-December 2019. Parenting style and personal hygiene questionnaires were completed by students’ mothers from four primary schools in North Jakarta (n 327). The study used the total sampling method Data collection was analyzed using Chi-square and Fisher exact test.Results: The study showed that 98.5% of students were raised with a non-exposure or authoritative parenting style, of which 57.5% of mothers had poor personal hygiene., Due to this, 61.8% of students had poor personal hygiene. Interestingly, there was a significant relationship between maternal personal hygiene and children's personal hygiene (p = 0.023). However, there was no significant relation between parenting style and children's personal hygiene (p = 0.065).Conclusions: There is no significant relationship between parenting style and children's personal hygiene. There is a significant relationship between maternal personal hygiene and children's personal hygiene. Therefore, parents need to apply the proper parenting style supported by other factors, such as good maternal personal hygiene, to encourage and educate children in achieving good personal hygiene.
{"title":"Relationship between Parenting Style and Maternal Personal Hygiene with Children’s Personal Hygiene in North Jakarta","authors":"Rebeka Milenia Magany, Prissilia Nanny Djaya, Felicia Kurniawan","doi":"10.15850/amj.v9n3.2294","DOIUrl":"https://doi.org/10.15850/amj.v9n3.2294","url":null,"abstract":"Background: Personal hygiene habits need to be practiced since early childhood because they are essential mechanisms in breaking the chain of transmission of various diseases. Important factors that affect children's personal hygiene are parenting style and maternal personal hygiene. This study aimed to determine the relationship between parenting style and maternal personal hygiene with their children’s personal hygiene.Methods: This study was an analytic observational study with a cross-sectional method conducted in July-December 2019. Parenting style and personal hygiene questionnaires were completed by students’ mothers from four primary schools in North Jakarta (n 327). The study used the total sampling method Data collection was analyzed using Chi-square and Fisher exact test.Results: The study showed that 98.5% of students were raised with a non-exposure or authoritative parenting style, of which 57.5% of mothers had poor personal hygiene., Due to this, 61.8% of students had poor personal hygiene. Interestingly, there was a significant relationship between maternal personal hygiene and children's personal hygiene (p = 0.023). However, there was no significant relation between parenting style and children's personal hygiene (p = 0.065).Conclusions: There is no significant relationship between parenting style and children's personal hygiene. There is a significant relationship between maternal personal hygiene and children's personal hygiene. Therefore, parents need to apply the proper parenting style supported by other factors, such as good maternal personal hygiene, to encourage and educate children in achieving good personal hygiene.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42298019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The incidence of stunting in Indonesia is high (30.8%), therefore, regular monitoring of children’s height growth is needed. However, during the Covid-19 pandemic, the health service’s checks are limited, as well as schools as a potential place to monitor children’s growth are closed. This study aimed to assess the effectiveness of online height measurement training for parents.Methods: This was a quantitative research with one group pre-and post-intervention design. It was conducted in a rural area in West Java, from August to November 2021. The parents of school students were included with a purposive sampling method. The training media was in the form of height measurement videos. The assessment of parents’ skills was an online check sheet with a Likert scale of 1–5 using the Whatsapp application. Analyzes were performed with the Paired T-Test.Results: In total, 86 parents were included, all of whom were mothers with the majority (51.2%) age range of 36–45 year. Parental education varied with most elementary school graduates (27.9%). Most mothers did not work (59.3%). As for the students, the majority were female students (60.5%) between 6–9 years old. The skill score before and after training was effective (d=2.04; p=<0.001).Conclusion: Online height measurement training using video has high effectiveness in improving parents’ skills to self-practice measurement at home.
{"title":"Effectiveness of Online Height Measurement Training for Parents","authors":"Fitri Yuniarti, Y. Zuhairini, F. Rinawan","doi":"10.15850/amj.v9n3.2622","DOIUrl":"https://doi.org/10.15850/amj.v9n3.2622","url":null,"abstract":"Background: The incidence of stunting in Indonesia is high (30.8%), therefore, regular monitoring of children’s height growth is needed. However, during the Covid-19 pandemic, the health service’s checks are limited, as well as schools as a potential place to monitor children’s growth are closed. This study aimed to assess the effectiveness of online height measurement training for parents.Methods: This was a quantitative research with one group pre-and post-intervention design. It was conducted in a rural area in West Java, from August to November 2021. The parents of school students were included with a purposive sampling method. The training media was in the form of height measurement videos. The assessment of parents’ skills was an online check sheet with a Likert scale of 1–5 using the Whatsapp application. Analyzes were performed with the Paired T-Test.Results: In total, 86 parents were included, all of whom were mothers with the majority (51.2%) age range of 36–45 year. Parental education varied with most elementary school graduates (27.9%). Most mothers did not work (59.3%). As for the students, the majority were female students (60.5%) between 6–9 years old. The skill score before and after training was effective (d=2.04; p=<0.001).Conclusion: Online height measurement training using video has high effectiveness in improving parents’ skills to self-practice measurement at home.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41791647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carissa Vania Pratama, Cep Juli, C. Calista, Suryani Gunadharma, Yusuf Wibisono, P. A. Ong
Background: There are high prevalence of cognitive impairment in patients with intracerebral hemorrhage (ICH) that may worsen the patients’ outcomes. Pneumonia, as the significant infection complication in stroke patients, may aggravate the decline in the cognitive outcome of patients. This study aimed to explore the cognitive outcomes among patients with or without pneumonia among patients with intracerebral hemorrhage.Methods: A cross-sectional retrospective analytical comparative numeric study was conducted from September 2020 to February 2021, using secondary data of patients with intracerebral hemorrhage admitted to the Department of Neurology Dr. Hasan Sadikin General Hospital in the year 2019. A total sampling method was employed. Data on pneumonia in stroke patients was retrieved, consisting of patients with pneumonia and without pneumonia. Data on Mini-Mental State Examination (MMSE) scores as the measures of cognitive outcomes were compared using the Mann-Whitney U test.Results: There were 108 patients with intracerebral hemorrhage included. There was a statistically significant difference (p value 0.049) in MMSE scores with median MMSE score for pneumonia patients (n = 27) and non-pneumonia patients (n = 81) were 25 and 21, respectively.Conclusions: Cognitive outcome is worse in patients with pneumonia than those without pneumonia. Early intervention is needed for intracerebral hemorrhage patients who develop pneumonia as a complication to improve the cognitive outcome.
{"title":"Cognitive Outcome of Intracerebral Hemorrhage Patients with and without Pneumonia","authors":"Carissa Vania Pratama, Cep Juli, C. Calista, Suryani Gunadharma, Yusuf Wibisono, P. A. Ong","doi":"10.15850/amj.v9n3.2320","DOIUrl":"https://doi.org/10.15850/amj.v9n3.2320","url":null,"abstract":"Background: There are high prevalence of cognitive impairment in patients with intracerebral hemorrhage (ICH) that may worsen the patients’ outcomes. Pneumonia, as the significant infection complication in stroke patients, may aggravate the decline in the cognitive outcome of patients. This study aimed to explore the cognitive outcomes among patients with or without pneumonia among patients with intracerebral hemorrhage.Methods: A cross-sectional retrospective analytical comparative numeric study was conducted from September 2020 to February 2021, using secondary data of patients with intracerebral hemorrhage admitted to the Department of Neurology Dr. Hasan Sadikin General Hospital in the year 2019. A total sampling method was employed. Data on pneumonia in stroke patients was retrieved, consisting of patients with pneumonia and without pneumonia. Data on Mini-Mental State Examination (MMSE) scores as the measures of cognitive outcomes were compared using the Mann-Whitney U test.Results: There were 108 patients with intracerebral hemorrhage included. There was a statistically significant difference (p value 0.049) in MMSE scores with median MMSE score for pneumonia patients (n = 27) and non-pneumonia patients (n = 81) were 25 and 21, respectively.Conclusions: Cognitive outcome is worse in patients with pneumonia than those without pneumonia. Early intervention is needed for intracerebral hemorrhage patients who develop pneumonia as a complication to improve the cognitive outcome.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43731792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The demand for novel, useful, potential, and safe antifungal drugs and rapid fungal susceptibility test methods due to antifungal resistance and high prevalence of Candida albicans infection are continuing. Therefore, this study aimed to assess and compare the antifungal activity of lactoferrin, apolactoferrin, and oligosaccharides isolated from human, bovine, goat, and formula milk against C. albicans on Mueller-Hinton agar supplemented with 2% glucose and 5 µg/mL methylene blue and sabouraud dextrose agar.Methods: Lactoferrin, apolactoferrin, and oligosaccharides were extracted from human, bovine, goat, and formula milk. Lactoferrin was identified using the Bradford test and Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis. Oligosaccharides were identified using Thin-Layer Chromatography. The antifungal activity of lactoferrin, apolactoferrin, and oligosaccharides against fluconazole-resistant Candida albicans ATCC 10231 was determined and compared using the disk diffusion method on Mueller-Hinton agar and sabouraud dextrose agar. The inhibition zone formed around the disk was observed after 24 hours of incubation.Results: Lactoferrin showed an inhibition zone on sabouraud dextrose agar against C. albicans, but not on Mueller-Hinton agar. Meanwhile, apolactoferrin and oligosaccharides showed no antifungal activity on both agar media.Conclusions: Different agar media in the diffusion disk test can give different results even though using the same test method and substance. These results could shed light and become the useful references on why some potential antifungals could yield a different results in in-vitro studies, in-vivo studies, or clinical trials.
{"title":"Anticandidal Activity of Lactoferrin, Apolactoferrin, and Oligosaccharides on Mueller-Hinton and Sabouraud Dextrose Agar against Fluconazole Resistant-Candida Albicans","authors":"M. M. Stella, S. S. Surja, Zita Arieselia","doi":"10.15850/amj.v9n3.2408","DOIUrl":"https://doi.org/10.15850/amj.v9n3.2408","url":null,"abstract":"Background: The demand for novel, useful, potential, and safe antifungal drugs and rapid fungal susceptibility test methods due to antifungal resistance and high prevalence of Candida albicans infection are continuing. Therefore, this study aimed to assess and compare the antifungal activity of lactoferrin, apolactoferrin, and oligosaccharides isolated from human, bovine, goat, and formula milk against C. albicans on Mueller-Hinton agar supplemented with 2% glucose and 5 µg/mL methylene blue and sabouraud dextrose agar.Methods: Lactoferrin, apolactoferrin, and oligosaccharides were extracted from human, bovine, goat, and formula milk. Lactoferrin was identified using the Bradford test and Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis. Oligosaccharides were identified using Thin-Layer Chromatography. The antifungal activity of lactoferrin, apolactoferrin, and oligosaccharides against fluconazole-resistant Candida albicans ATCC 10231 was determined and compared using the disk diffusion method on Mueller-Hinton agar and sabouraud dextrose agar. The inhibition zone formed around the disk was observed after 24 hours of incubation.Results: Lactoferrin showed an inhibition zone on sabouraud dextrose agar against C. albicans, but not on Mueller-Hinton agar. Meanwhile, apolactoferrin and oligosaccharides showed no antifungal activity on both agar media.Conclusions: Different agar media in the diffusion disk test can give different results even though using the same test method and substance. These results could shed light and become the useful references on why some potential antifungals could yield a different results in in-vitro studies, in-vivo studies, or clinical trials.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46184494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Timoty Krisna Sukoco, Dini Hidayat, R. T. D. Judistiani
Background: The prevalence of obesity is increasing globally, causing various possible disorders and complications. Maternal and perinatal morbidity and mortality might potentially be affected by maternal obesity. This study aimed to evaluate the association between maternal obesity and pregnancy outcomes. Methods: This retrospective cohort study was part of a larger cohort study performed from July 2016 to July 2017 in West Java, including 223 pregnant women with normal fetuses, who were obese or non-obese pre-pregnancy. Underweight women were excluded. Data on pregnancy outcomes consisting of Caesarean section, preeclampsia, premature rupture of membrane (PROM), preterm birth, post-term birth, small for gestational age (SGA), and large for gestational age (LGA) were collected. The association with maternal obesity was analyzed using the Fisher’s Exact Test to determine the association with a 95% confidence interval, and a p-value <0.05 was considered significant. Results: There was an association between maternal obesity and Caesarean section, with an increased risk in obese mothers compared to non-obese mothers (RR 2.398 CI 1.328-4.329). There was no significant association between maternal obesity and preeclampsia, PROM, preterm birth, post-term birth, SGA, and LGA. Conclusion: Maternal obesity is associated with Caesarean section. A more comprehensive approach is essential for obese pregnant women to ensure the health of both the mother and the infant.
背景:肥胖的患病率在全球范围内呈上升趋势，引起各种可能的疾病和并发症。产妇和围产期发病率和死亡率可能受到产妇肥胖的潜在影响。本研究旨在评估孕妇肥胖与妊娠结局之间的关系。方法:该回顾性队列研究是2016年7月至2017年7月在西爪哇进行的一项更大规模队列研究的一部分，其中包括223名怀孕前肥胖或非肥胖的正常胎儿孕妇。体重过轻的女性被排除在外。收集了包括剖腹产、先兆子痫、胎膜早破(PROM)、早产、产后、小胎龄(SGA)和大胎龄(LGA)在内的妊娠结局数据。使用Fisher精确检验分析与母亲肥胖的关联，确定95%置信区间的关联，p值<0.05被认为是显著的。结果:产妇肥胖与剖腹产之间存在关联，与非肥胖母亲相比，肥胖母亲的风险增加(RR 2.398 CI 1.328-4.329)。产妇肥胖与子痫前期、胎膜早破、早产、产后、SGA和LGA之间无显著关联。结论:产妇肥胖与剖宫产有关。对于肥胖孕妇来说，更全面的方法是必不可少的，以确保母亲和婴儿的健康。
{"title":"Association of Maternal Obesity and Pregnancy Outcomes","authors":"Timoty Krisna Sukoco, Dini Hidayat, R. T. D. Judistiani","doi":"10.15850/amj.v9n2.2632","DOIUrl":"https://doi.org/10.15850/amj.v9n2.2632","url":null,"abstract":"Background: The prevalence of obesity is increasing globally, causing various possible disorders and complications. Maternal and perinatal morbidity and mortality might potentially be affected by maternal obesity. This study aimed to evaluate the association between maternal obesity and pregnancy outcomes. Methods: This retrospective cohort study was part of a larger cohort study performed from July 2016 to July 2017 in West Java, including 223 pregnant women with normal fetuses, who were obese or non-obese pre-pregnancy. Underweight women were excluded. Data on pregnancy outcomes consisting of Caesarean section, preeclampsia, premature rupture of membrane (PROM), preterm birth, post-term birth, small for gestational age (SGA), and large for gestational age (LGA) were collected. The association with maternal obesity was analyzed using the Fisher’s Exact Test to determine the association with a 95% confidence interval, and a p-value <0.05 was considered significant. Results: There was an association between maternal obesity and Caesarean section, with an increased risk in obese mothers compared to non-obese mothers (RR 2.398 CI 1.328-4.329). There was no significant association between maternal obesity and preeclampsia, PROM, preterm birth, post-term birth, SGA, and LGA. Conclusion: Maternal obesity is associated with Caesarean section. A more comprehensive approach is essential for obese pregnant women to ensure the health of both the mother and the infant.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47805041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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