Resistensi terhadap beberapa antibiotik disebabkan oleh adanya penggunaan antibiotik yang rasional masih sering diabaikan. Kemangi (Ocimum basilicum L.) merupakan salah satu tanaman yang memiliki aktivitas antibakteri. Salah satu kandungan kemangi yang diduga memiliki aktivitas antibakteri yaitu minyak atsiri. Penelitian terkait aktivitas antibakteri pada kemangi sebagian besar dilakukan dengan menggunakan sampel segar maupun simplisia dari daun kemangi yang kemudian diekstraksi, namun ada beberapa uji yang menggunakan bagian batang. Metode uji aktivitas antibakteri kemangi terhadap beberapa bakteri gram positif dan gram negatif dilakukan dengan metode difusi cakram agar, difusi cakram kertas, mikrodilusi broth, mikrodilusi dalam microtiter plates, difusi sumuran agar, dan macro-dilusi. Hasil uji aktivitas antibakteri menunjukkan bahwa kandungan minyak atsiri yang terdapat dalam kemangi memiliki aktivitas penghambat aktivitas bakteri.
{"title":"Kemangi (Ocimum basilicum L.): Kandungan Kimia, Teknik Ekstraksi, dan Uji Aktivitas Antibakteri","authors":"Adithya Guntur, Monica Selena, Anastasia Bella, Giovanny Leonarda, Adelsiana Leda, Dewi Setyaningsih, Florentinus Dika Octa Riswanto","doi":"10.22146/jfps.3376","DOIUrl":"https://doi.org/10.22146/jfps.3376","url":null,"abstract":"Resistensi terhadap beberapa antibiotik disebabkan oleh adanya penggunaan antibiotik yang rasional masih sering diabaikan. Kemangi (Ocimum basilicum L.) merupakan salah satu tanaman yang memiliki aktivitas antibakteri. Salah satu kandungan kemangi yang diduga memiliki aktivitas antibakteri yaitu minyak atsiri. Penelitian terkait aktivitas antibakteri pada kemangi sebagian besar dilakukan dengan menggunakan sampel segar maupun simplisia dari daun kemangi yang kemudian diekstraksi, namun ada beberapa uji yang menggunakan bagian batang. Metode uji aktivitas antibakteri kemangi terhadap beberapa bakteri gram positif dan gram negatif dilakukan dengan metode difusi cakram agar, difusi cakram kertas, mikrodilusi broth, mikrodilusi dalam microtiter plates, difusi sumuran agar, dan macro-dilusi. Hasil uji aktivitas antibakteri menunjukkan bahwa kandungan minyak atsiri yang terdapat dalam kemangi memiliki aktivitas penghambat aktivitas bakteri.","PeriodicalId":314392,"journal":{"name":"Journal of Food and Pharmaceutical Sciences","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116936335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cangkang kapsul komersial umumnya terbuat dari bahan gelatin, tetapi juga dapat dibuat dari pati. Salah satu sumber pati terdapat pada kulit kentang (Solanum tuberosum L). Pengembangan cangkang kapsul keras dari bahan alam sedang menjadi trend saat ini, namun cangkang kapsul keras dari bahan baku pati mudah rapuh tanpa plasticizer. Madu dapat digunakan sebagai plasticizer untuk meningkatkan elastisitas kapsul agar tidak mudah pecah atau rapuh. Penelitian ini bertujuan untuk menguji pengaruh penambahan pati kulit kentang dengan berbagai konsentrasi terhadap karakteristik fisik cangkang kapsul keras dan pengaruh madu sebagai plasticizer pengganti gliserol. Cangkang kapsul keras dibuat dengan penambahan pati dengan berbagai konsentrasi 0% (FI), 2% (FII), 4% (FIII), 6% (FIV), 8% (FV) dengan penambahan madu 2,5%, Karagenan 2 %, sukrosa 2,5% dan aquadest ditambahkan 100%. Cangkang kapsul keras dibuat secara manual dengan cara mencelupkan cetakan ke dalam larutan masing-masing formula kemudian di oven. Karakteristik fisik cangkang kapsul keras dievaluasi dan dibandingkan dengan cangkang kapsul keras komersial nomor 0 (nol). Hasil penelitian menyimpulkan bahwa FII merupakan formula terbaik dan memenuhi standar karakteristik fisik cangkang kapsul keras.
{"title":"Formulasi dan Karakterisasi Cangkang Kapsul dari Pati Kulit Kentang (Solanum tuberosum L.) dan Madu sebagai Plasticizer","authors":"Indah Tri Lestari, Andi Asma Atmadi Putri, Fauzia Nurul Fajriah, Rizki Awaluddin, Aulia Rahma","doi":"10.22146/jfps.3301","DOIUrl":"https://doi.org/10.22146/jfps.3301","url":null,"abstract":"Cangkang kapsul komersial umumnya terbuat dari bahan gelatin, tetapi juga dapat dibuat dari pati. Salah satu sumber pati terdapat pada kulit kentang (Solanum tuberosum L). Pengembangan cangkang kapsul keras dari bahan alam sedang menjadi trend saat ini, namun cangkang kapsul keras dari bahan baku pati mudah rapuh tanpa plasticizer. Madu dapat digunakan sebagai plasticizer untuk meningkatkan elastisitas kapsul agar tidak mudah pecah atau rapuh. Penelitian ini bertujuan untuk menguji pengaruh penambahan pati kulit kentang dengan berbagai konsentrasi terhadap karakteristik fisik cangkang kapsul keras dan pengaruh madu sebagai plasticizer pengganti gliserol. Cangkang kapsul keras dibuat dengan penambahan pati dengan berbagai konsentrasi 0% (FI), 2% (FII), 4% (FIII), 6% (FIV), 8% (FV) dengan penambahan madu 2,5%, Karagenan 2 %, sukrosa 2,5% dan aquadest ditambahkan 100%. Cangkang kapsul keras dibuat secara manual dengan cara mencelupkan cetakan ke dalam larutan masing-masing formula kemudian di oven. Karakteristik fisik cangkang kapsul keras dievaluasi dan dibandingkan dengan cangkang kapsul keras komersial nomor 0 (nol). Hasil penelitian menyimpulkan bahwa FII merupakan formula terbaik dan memenuhi standar karakteristik fisik cangkang kapsul keras.","PeriodicalId":314392,"journal":{"name":"Journal of Food and Pharmaceutical Sciences","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127552207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The fruit produced from Avicennia tree (in the form of ethanol extract) has the property of reducing blood glucose levels (oral antidiabetic mellitus) with an effective dose of 10 mg / 50 kg human body weight. Most of the elderly with diabetes mellitus in Indonesia are aged 60-74 years (83.3%) who have a decreased ability to swallow drugs. In addition, antidiabetic drugs are expected to be able to produce fast action, so that it can reduce blood sugar levels immediately. Therefore, the Avicennia fruit ethanol extract formulated in the form of Orally Disintegrating Tablet (ODT). The aim of this study was to determine the effect of Starch 1500 and Crospovidone as a superdisintegrant in either single or combination use in the Avicennia fruit ethanol extract ODT formulation. The ODT was made by direct compression. There were three formulas that was carried out in this study : FI with 10 mg of Starch 1500, FII with 10 mg of Crospovidone and FIII with a combination of superdisintegrant Starch 1500 and Crospovidone (7 mg and 3 mg). In this study it could be conclued that the best compatible superdisintegrant in ODT for Avicennia fruit ethanol extract was Crospovidone, not combination with Starch 1500.
{"title":"Orally Disintegrating Tablet Formulation of Avicennia Fruit Ethanol Extract (Avicennia marina)","authors":"Ungsari Rizki eka Purwanto, Maria Caecilia Nanny Setiawati, Ika Puspitaningrum, Siti Munisih","doi":"10.22146/jfps.2488","DOIUrl":"https://doi.org/10.22146/jfps.2488","url":null,"abstract":"The fruit produced from Avicennia tree (in the form of ethanol extract) has the property of reducing blood glucose levels (oral antidiabetic mellitus) with an effective dose of 10 mg / 50 kg human body weight. Most of the elderly with diabetes mellitus in Indonesia are aged 60-74 years (83.3%) who have a decreased ability to swallow drugs. In addition, antidiabetic drugs are expected to be able to produce fast action, so that it can reduce blood sugar levels immediately. Therefore, the Avicennia fruit ethanol extract formulated in the form of Orally Disintegrating Tablet (ODT). The aim of this study was to determine the effect of Starch 1500 and Crospovidone as a superdisintegrant in either single or combination use in the Avicennia fruit ethanol extract ODT formulation. The ODT was made by direct compression. There were three formulas that was carried out in this study : FI with 10 mg of Starch 1500, FII with 10 mg of Crospovidone and FIII with a combination of superdisintegrant Starch 1500 and Crospovidone (7 mg and 3 mg). In this study it could be conclued that the best compatible superdisintegrant in ODT for Avicennia fruit ethanol extract was Crospovidone, not combination with Starch 1500.","PeriodicalId":314392,"journal":{"name":"Journal of Food and Pharmaceutical Sciences","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130353341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Risti Zahroh, Isma Kurniatanty, J. Sholihah, E. Widowati
Hypertension or high blood pressure is a condition when there is an increase in blood pressure above the normal threshold (> 140/90 mmHg). The bioactive compounds in red ginger are dominated by the terpene group which has the ability to inhibit the action of Angiotensin Converting Enzyme (ACE-inhibitor). The interaction between ACE-inhibitory peptides can be predicted by the in silico method. The in silico method was used to predict the interaction and binding energy between bioactive compounds in red ginger ethanol extract (ligand) and ACE protein (receptor) which acts as an antihypertensive. The results of GC-MS obtained as many as 5 compounds (zingiberene, farnesene, ß -sesquiphellandrene, alpha-curcumene and trans-beta-farnesene. The docking results showed the lowest binding energy values for each compound sequentially for ACE-trans beta farnesene, ACE-alpha curcumene, ACE-zingiberene, ACE-farnesene, ACE-beta sesquiphellandrene are -5.14 kcal/mol, -5.61 kcal/mol , -6.20 kcal/mol, -5.66 kcal/mol, and -6.55 kcal/mol. Based on these results, the lowest bond energy among the 5 compounds was -6.55 kcal/mol at ACE-beta sesquiphellandrene docking, so the red ginger ethanol extract can be proposed and tested further as a clinical candidate for antihypertensive drugs.
{"title":"Antihypertension Activity Test oOf Red Ginger (Zingiber officinale Var. Rubrum Roscoe) Ethanol Extract by In Silico Method","authors":"Risti Zahroh, Isma Kurniatanty, J. Sholihah, E. Widowati","doi":"10.22146/jfps.2694","DOIUrl":"https://doi.org/10.22146/jfps.2694","url":null,"abstract":"Hypertension or high blood pressure is a condition when there is an increase in blood pressure above the normal threshold (> 140/90 mmHg). The bioactive compounds in red ginger are dominated by the terpene group which has the ability to inhibit the action of Angiotensin Converting Enzyme (ACE-inhibitor). The interaction between ACE-inhibitory peptides can be predicted by the in silico method. The in silico method was used to predict the interaction and binding energy between bioactive compounds in red ginger ethanol extract (ligand) and ACE protein (receptor) which acts as an antihypertensive. The results of GC-MS obtained as many as 5 compounds (zingiberene, farnesene, ß -sesquiphellandrene, alpha-curcumene and trans-beta-farnesene. The docking results showed the lowest binding energy values for each compound sequentially for ACE-trans beta farnesene, ACE-alpha curcumene, ACE-zingiberene, ACE-farnesene, ACE-beta sesquiphellandrene are -5.14 kcal/mol, -5.61 kcal/mol , -6.20 kcal/mol, -5.66 kcal/mol, and -6.55 kcal/mol. Based on these results, the lowest bond energy among the 5 compounds was -6.55 kcal/mol at ACE-beta sesquiphellandrene docking, so the red ginger ethanol extract can be proposed and tested further as a clinical candidate for antihypertensive drugs.","PeriodicalId":314392,"journal":{"name":"Journal of Food and Pharmaceutical Sciences","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134535988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sekar Ayu Pawestri, A. Nugroho, E. Lukitaningsih, Purwantiningsih
Compartmental modeling analysis was used to understand the transport mechanism of drugs in biological systems by computation presented as intercompartmental flows or material. This study was aimed to implement compartmental modeling analysis for in vitro permeation studies in transdermal delivery. The cumulative drug transported versus time were obtained based on the previous report and implemented the two structural different proposed models. WinSAAM software (Windows-based Simulation Analysis and Modeling-WinSAAM Project Group, University of Pennsylvania) was used to analyze data with compartmental analysis. The chosen models were selected through visual and numeric evaluation. The best model had been chosen and could figure out the drug transport kinetics in the biological system. The compartmental modeling approach was helpful used in understanding drug transport mechanisms in transdermal delivery and effectively estimate the drug transport parameter.
{"title":"Compartmental Modeling Approach: Application on Transdermal Delivery for In Vitro Drug Permeation Mechanism Analysis","authors":"Sekar Ayu Pawestri, A. Nugroho, E. Lukitaningsih, Purwantiningsih","doi":"10.22146/jfps.2198","DOIUrl":"https://doi.org/10.22146/jfps.2198","url":null,"abstract":"Compartmental modeling analysis was used to understand the transport mechanism of drugs in biological systems by computation presented as intercompartmental flows or material. This study was aimed to implement compartmental modeling analysis for in vitro permeation studies in transdermal delivery. The cumulative drug transported versus time were obtained based on the previous report and implemented the two structural different proposed models. WinSAAM software (Windows-based Simulation Analysis and Modeling-WinSAAM Project Group, University of Pennsylvania) was used to analyze data with compartmental analysis. The chosen models were selected through visual and numeric evaluation. The best model had been chosen and could figure out the drug transport kinetics in the biological system. The compartmental modeling approach was helpful used in understanding drug transport mechanisms in transdermal delivery and effectively estimate the drug transport parameter.","PeriodicalId":314392,"journal":{"name":"Journal of Food and Pharmaceutical Sciences","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127849240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Sahubawa, Ustadi, Leni Sophia Heliana, Rosdiana
Yellowfin tuna is one of Indonesia's main export commodities, its meat contains high protein and can be processed into a variety of commercial food products. In the processing of loin, fillet and tuna steak, ± 10% of flaked meat is produced which can be used for processing commercial products. Spaghetti is one of the commercial products that is easily processed with raw materials and additives that are cheap and easy to obtain as well as halal and thoyib. The raw materials used are tuna flakes, spaghetti noodles and seasonings. The research objective was to analyze the chemical composition of tuna flakes and tuna topping spaghetti as well as the added value and level of consumer preference. This research uses laboratory methods, the percentage of additional selling value and consumer preferences. Proximate chemical composition of tuna flakes, namely: water content (74.80 - 75.25%); protein (16.35 - 17.00%); fat (1.43 - 1.50%); minerals (5.38 - 5.45%); carbohydrates (0.65 - 0.80%). Chemical composition of tuna topping spaghetti, namely: water content (62.73 - 69.13%); protein (7.08 - 8.34%); fat (0.42 - 0.76%); minerals/ash (0.93 - 1.16%) and carbohydrates (24.41 - 25.54%). The added value of tuna flakes in the processing of tuna topping spaghetti for two packages of spaghetti noodles (18 portions) is Rp. 147,355 (80.79%). The level of consumer preference (25 panelists) towards the visual value of tuna topping spaghetti is “very like” (76.0%) and “like” (24%); smell values, namely "really like" (72.0%) and "like" (28%); the value of taste, namely "really like" (80.0%) and "like" (20%); Texture values are “really like” (80.0%) and “like” (20%) and taste values are “really like” (76.0%) and “like” (24%).
{"title":"Increased Value Added of Tuna Flakes (By-Product) from Steak Processing Through Development of Halal Commercial Food Products (Tuna Topping Spaghetti)","authors":"L. Sahubawa, Ustadi, Leni Sophia Heliana, Rosdiana","doi":"10.22146/jfps.1911","DOIUrl":"https://doi.org/10.22146/jfps.1911","url":null,"abstract":"Yellowfin tuna is one of Indonesia's main export commodities, its meat contains high protein and can be processed into a variety of commercial food products. In the processing of loin, fillet and tuna steak, ± 10% of flaked meat is produced which can be used for processing commercial products. Spaghetti is one of the commercial products that is easily processed with raw materials and additives that are cheap and easy to obtain as well as halal and thoyib. The raw materials used are tuna flakes, spaghetti noodles and seasonings. The research objective was to analyze the chemical composition of tuna flakes and tuna topping spaghetti as well as the added value and level of consumer preference. This research uses laboratory methods, the percentage of additional selling value and consumer preferences. Proximate chemical composition of tuna flakes, namely: water content (74.80 - 75.25%); protein (16.35 - 17.00%); fat (1.43 - 1.50%); minerals (5.38 - 5.45%); carbohydrates (0.65 - 0.80%). Chemical composition of tuna topping spaghetti, namely: water content (62.73 - 69.13%); protein (7.08 - 8.34%); fat (0.42 - 0.76%); minerals/ash (0.93 - 1.16%) and carbohydrates (24.41 - 25.54%). The added value of tuna flakes in the processing of tuna topping spaghetti for two packages of spaghetti noodles (18 portions) is Rp. 147,355 (80.79%). The level of consumer preference (25 panelists) towards the visual value of tuna topping spaghetti is “very like” (76.0%) and “like” (24%); smell values, namely \"really like\" (72.0%) and \"like\" (28%); the value of taste, namely \"really like\" (80.0%) and \"like\" (20%); Texture values are “really like” (80.0%) and “like” (20%) and taste values are “really like” (76.0%) and “like” (24%).","PeriodicalId":314392,"journal":{"name":"Journal of Food and Pharmaceutical Sciences","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123720140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Many people choose alternative medicines for Diabetes Mellitus (DM) disorders, such as herbal plants to suppress the occurrence of the disease widely. In general, DM occurs when the pancreas doesn't produce enough insulin, or when the body can't effectively use the insulin which it produces. The use of medicinal plants to treat various diseases has shown minimal side effects. Indonesia is one of the countries that has used plants as traditional medicine since ancient times. In Indonesia, thousands of species of medicinal plants have been studied to address health problems. Among the medicinal plants that have been studied is the Neem plant (Azadirachta indica A. Juss) which has been shown to cure various diseases. This review article describes the potential of the Neem plant as an antidiabetic. The results of this literature review, in the form of Neem herbal extracts, have quite good potential as an antidiabetic because they contain several compounds such as meliacinolin, azachdirichtin, gliserid oil, acetyl oxyturanoe acid and other compounds that can also act as antidiabetic.
许多人选择替代药物治疗糖尿病(DM)疾病，如草药植物，以抑制疾病的发生。一般来说，糖尿病发生在胰腺不能产生足够的胰岛素，或者当身体不能有效地利用它产生的胰岛素时。使用药用植物治疗各种疾病的副作用很小。印度尼西亚是自古以来就把植物作为传统药物的国家之一。在印度尼西亚，研究了数千种药用植物以解决健康问题。在被研究的药用植物中，印楝树(Azadirachta indica A. Juss)已被证明可以治疗多种疾病。这篇综述文章描述了印度楝树作为抗糖尿病植物的潜力。这篇文献综述的结果表明，印度楝草提取物具有很好的抗糖尿病潜力，因为它们含有多种化合物，如meliacinolin、azachdirichtin、gliserid油、acetyl oxyturanoe acid和其他化合物，也可以起到抗糖尿病的作用。
{"title":"Potential Effects of Neem Plants (Azadirachta indica A. Juss.) as Antidiabetic Potensi Tanaman Mimba (Azadirachta indica A. Juss.) sebagai Antidiabetes","authors":"Putri Rachma Novitasari, Baiq Maylinda Gemantari, Syarifatul Mufidah, Prita Anggraini Kartika Sari","doi":"10.22146/jfps.1938","DOIUrl":"https://doi.org/10.22146/jfps.1938","url":null,"abstract":"Many people choose alternative medicines for Diabetes Mellitus (DM) disorders, such as herbal plants to suppress the occurrence of the disease widely. In general, DM occurs when the pancreas doesn't produce enough insulin, or when the body can't effectively use the insulin which it produces. The use of medicinal plants to treat various diseases has shown minimal side effects. Indonesia is one of the countries that has used plants as traditional medicine since ancient times. In Indonesia, thousands of species of medicinal plants have been studied to address health problems. Among the medicinal plants that have been studied is the Neem plant (Azadirachta indica A. Juss) which has been shown to cure various diseases. This review article describes the potential of the Neem plant as an antidiabetic. The results of this literature review, in the form of Neem herbal extracts, have quite good potential as an antidiabetic because they contain several compounds such as meliacinolin, azachdirichtin, gliserid oil, acetyl oxyturanoe acid and other compounds that can also act as antidiabetic.","PeriodicalId":314392,"journal":{"name":"Journal of Food and Pharmaceutical Sciences","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132065098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Olabanji, Emmanuel Olugbenga Akinkunmi, O. NancyAniki, S. Arowosegbe, O. S. Ajayi, Reuben O. Yoade, Funmilola Fasesan
The anti- microbial activity tests of the seed oil, NaOH and ash soaps of the seed oil, of C.albidum were carried out to determine their effectiveness against gram+, gram– bacteria and some fungi strains. The proximate analysis of C.albidum seeds was performed to determine its nutritional benefits to mankind. Agar diffusion tests using Disc diffusion for the pure oils and soaps while the cup plate test method for dilutions was used in the determination of in-vitro activities. Standard methods as described by AOAC, (1990); AOAC, (1984) and Kjeldahl method described by Chang (2003) were used for proximate determinations. The results show the activity of the oil against Klebsiella pneumonia at a concentration as low as 10 mg/ml. The ash-soap of the leaves shows the highest antimicrobial activities because its MIC is the closest to the standard, Streptomycin. It possesses activity against Escherichia coli and Klebsiella pneumonia at a concentration as low as 5mg/ml. The % proximate analysis composition shows Moisture content, Ash content, Crude Fibre, fat/Oil, Protein, Carbohydrates as follows (14.98, 1.90, 2.09, 2.38, 12.14 and 67.65)%. The study concluded by unleashing the great potential of Chrysophyllum albidum seeds as a useful raw material in food, cosmetics and pharmaceutical industries rather than being regarded as waste in the environment
{"title":"Exploring the Antimicrobial Activities of Chrysophyllum albidum Seed oil in Pharmaceutical and the Seeds in Food industry.","authors":"I. Olabanji, Emmanuel Olugbenga Akinkunmi, O. NancyAniki, S. Arowosegbe, O. S. Ajayi, Reuben O. Yoade, Funmilola Fasesan","doi":"10.22146/JFPS.1465","DOIUrl":"https://doi.org/10.22146/JFPS.1465","url":null,"abstract":"The anti- microbial activity tests of the seed oil, NaOH and ash soaps of the seed oil, of C.albidum were carried out to determine their effectiveness against gram+, gram– bacteria and some fungi strains. The proximate analysis of C.albidum seeds was performed to determine its nutritional benefits to mankind. Agar diffusion tests using Disc diffusion for the pure oils and soaps while the cup plate test method for dilutions was used in the determination of in-vitro activities. Standard methods as described by AOAC, (1990); AOAC, (1984) and Kjeldahl method described by Chang (2003) were used for proximate determinations. The results show the activity of the oil against Klebsiella pneumonia at a concentration as low as 10 mg/ml. The ash-soap of the leaves shows the highest antimicrobial activities because its MIC is the closest to the standard, Streptomycin. It possesses activity against Escherichia coli and Klebsiella pneumonia at a concentration as low as 5mg/ml. The % proximate analysis composition shows Moisture content, Ash content, Crude Fibre, fat/Oil, Protein, Carbohydrates as follows (14.98, 1.90, 2.09, 2.38, 12.14 and 67.65)%. The study concluded by unleashing the great potential of Chrysophyllum albidum seeds as a useful raw material in food, cosmetics and pharmaceutical industries rather than being regarded as waste in the environment","PeriodicalId":314392,"journal":{"name":"Journal of Food and Pharmaceutical Sciences","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128634980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Crude Palm Oil (CPO) is palm oil obtained from the extraction or compression process of oil palm fruit flesh and has not been purified. Palm oil is usually used for food, cosmetic industry, chemical industry, and animal feed industry. Increasingly open insight and increasing consumer awareness of the importance of food safety and quality assurance supported by technological developments and laboratory analysis methods, new types of contaminants in food products are also found. Currently, the Indonesian government is facing challenges regarding the issue of 3-monochloro-1,2-propanediol ester (3-MCPD Ester) and glycidyl ester (GE) in palm oil which can hamper Indonesia's palm oil trade in the future. The practice in the field affects the quality of CPO and the retrieval of low-quality CPO is mixed with high-quality CPO. And the length of time the process of pumping CPO from reclaimed tanks to VCT affects the quality of CPO. So this study aims to modify the pumping time and storage time of CPO from Reclaimed tanks to VCT by mixing samples from VCT (fresh CPO) and samples from Reclaimed tanks (lower quality CPO).
{"title":"Study of Crude Palm Oil (CPO) Handling and Storage Process in Palm Oil Mills in an Effort to Improve CPO Quality and Reduce the Risk of Contaminants Formation","authors":"Anita Syafrianti, Z. Lubis, J. Elisabeth","doi":"10.22146/jfps.2091","DOIUrl":"https://doi.org/10.22146/jfps.2091","url":null,"abstract":"Crude Palm Oil (CPO) is palm oil obtained from the extraction or compression process of oil palm fruit flesh and has not been purified. Palm oil is usually used for food, cosmetic industry, chemical industry, and animal feed industry. Increasingly open insight and increasing consumer awareness of the importance of food safety and quality assurance supported by technological developments and laboratory analysis methods, new types of contaminants in food products are also found. Currently, the Indonesian government is facing challenges regarding the issue of 3-monochloro-1,2-propanediol ester (3-MCPD Ester) and glycidyl ester (GE) in palm oil which can hamper Indonesia's palm oil trade in the future. The practice in the field affects the quality of CPO and the retrieval of low-quality CPO is mixed with high-quality CPO. And the length of time the process of pumping CPO from reclaimed tanks to VCT affects the quality of CPO. So this study aims to modify the pumping time and storage time of CPO from Reclaimed tanks to VCT by mixing samples from VCT (fresh CPO) and samples from Reclaimed tanks (lower quality CPO).","PeriodicalId":314392,"journal":{"name":"Journal of Food and Pharmaceutical Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125408511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ayu Ina Solichah, Khoerul Anwar, Abdul Rohman, Nanang Fakhrudin
Artocarpus merupakan tumbuhan genus utama keluarga Moraceae dengan jumlah spesies hampir 1.400. Beberapa spesies dari genus tersebut dapat dimanfaatkan sebagai makanan dan obat tradisional di Asia Tenggara, termasuk Indonesia. Jenis yang banyak tumbuh di Indonesia yaitu Artocarpus altilis (sukun), Artocarpus camansi (kluwih), Artocarpus heterophyllus (nangka), Artocarpus integer (cempedak), dan Artocarpus odoratissimus (tarap). Tumbuhan tersebut memiliki potensi sebagai bahan obat dan punya nilai gizi yang tinggi. Review ini bertujuan untuk mengkaji perbedaan antar spesies, profil fitokimia, dan aktivitasnya sebagai antioksidan dari kelima tumbuhan tersebut. Narrative review ini ditulis berdasarkan penelusuran literatur yang berupa publikasi artikel penelitian yang ada di basis data Google Scholar, PubMed, dan Science Direct. Selain itu digunakan sumber pustaka lain berupa buku dan naskah tugas akhir untuk memperkaya isi artikel. Hasil kajian literatur terhadap 5 tumbuhan tersebut menunjukkan bahwa beberapa tumbuhan memiliki kemiripan morfologi daun walaupun secara fisik masih bisa dibedakan. Profil fitokimianya memiliki keunikan dengan kandungan utama berupa senyawa fenolik termasuk flavonoid, stilbenoid, arilbenzofuron, dan neolignan yang tersebar pada bagian daun, buah, bunga, dan kulit. Keunikan tersebut ditemui dengan adanya senyawa golongan flavonoid terprenilasi dan tergeranilasi. Senyawa fenolik tersebut mempunyai kemampuan sebagai antioksidan pada beberapa model uji dan potensial untuk dikembangakan sebagai antioksidan atau kandidat obat terutama untuk penyakit yang melibatkan mekanisme radikal bebas dalam mekanisme patofisiologinya.
{"title":"Profil Fitokimia dan Aktivitas Antioksidan Beberapa Tumbuhan Genus Artocarpus di Indonesia","authors":"Ayu Ina Solichah, Khoerul Anwar, Abdul Rohman, Nanang Fakhrudin","doi":"10.22146/jfps.2026","DOIUrl":"https://doi.org/10.22146/jfps.2026","url":null,"abstract":"Artocarpus merupakan tumbuhan genus utama keluarga Moraceae dengan jumlah spesies hampir 1.400. Beberapa spesies dari genus tersebut dapat dimanfaatkan sebagai makanan dan obat tradisional di Asia Tenggara, termasuk Indonesia. Jenis yang banyak tumbuh di Indonesia yaitu Artocarpus altilis (sukun), Artocarpus camansi (kluwih), Artocarpus heterophyllus (nangka), Artocarpus integer (cempedak), dan Artocarpus odoratissimus (tarap). Tumbuhan tersebut memiliki potensi sebagai bahan obat dan punya nilai gizi yang tinggi. Review ini bertujuan untuk mengkaji perbedaan antar spesies, profil fitokimia, dan aktivitasnya sebagai antioksidan dari kelima tumbuhan tersebut. Narrative review ini ditulis berdasarkan penelusuran literatur yang berupa publikasi artikel penelitian yang ada di basis data Google Scholar, PubMed, dan Science Direct. Selain itu digunakan sumber pustaka lain berupa buku dan naskah tugas akhir untuk memperkaya isi artikel. Hasil kajian literatur terhadap 5 tumbuhan tersebut menunjukkan bahwa beberapa tumbuhan memiliki kemiripan morfologi daun walaupun secara fisik masih bisa dibedakan. Profil fitokimianya memiliki keunikan dengan kandungan utama berupa senyawa fenolik termasuk flavonoid, stilbenoid, arilbenzofuron, dan neolignan yang tersebar pada bagian daun, buah, bunga, dan kulit. Keunikan tersebut ditemui dengan adanya senyawa golongan flavonoid terprenilasi dan tergeranilasi. Senyawa fenolik tersebut mempunyai kemampuan sebagai antioksidan pada beberapa model uji dan potensial untuk dikembangakan sebagai antioksidan atau kandidat obat terutama untuk penyakit yang melibatkan mekanisme radikal bebas dalam mekanisme patofisiologinya.","PeriodicalId":314392,"journal":{"name":"Journal of Food and Pharmaceutical Sciences","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121720461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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