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Retinal displacement following successful pars plana vitrectomy for rhegmatogenous retinal detachment 孔源性视网膜脱离平坦部玻璃体切除术后视网膜移位
IF 0.2 Pub Date : 2023-04-01 DOI: 10.4103/ejos.ejos_114_22
Amr Ali, Y. Serag, Hesham Eltoukhy, Raouf Gaber, Tamer Wasfy
Background The appearance of hyperfluorescent lines next to the retinal blood vessels after successful retinal detachment (RD) surgery was explained by the occurrence of retinal displacement. This can attribute to the metamorphopsia experienced by some patients after their surgeries. Patients and methods A prospective interventional study was performed that included 30 eyes of 30 patients with primary rhegmatogenous RD, who had undergone successful RD surgery via pars plana vitrectomy and silicone oil tamponade. The entire patients had preoperative and postoperative fundus autofluorescence and optical coherence tomography. They were followed up for 3 months after surgery with testing of the best-corrected visual acuity and Amsler grid testing. Results The mean age of the included group was 53.7±9.2 years, and 17 (56.7%) patients were males. The most frequent tear site was upper temporal (43.3%), followed by multiple peripheral (23.33%), upper nasal (13.3%), lower temporal (13.3%), and the least was lower nasal (6.7%). Retinal displacement was detected by hyperfluorescent lines adjacent to the retinal blood vessels in the fundus autofluorescence imaging in 16 eyes (53.3% with 95% confidence interval: 36.7–70.0%). Patients with retinal displacement were significantly younger than patients without (P=0.019). The presence of proliferative vitreoretinopathy was significantly related to the occurrence of displacement (P=0.028). Metamorphopsia was significantly more frequent among patients with displacement (P<0.001). Conclusion Retinal displacement had a high possibility to occur after successful repair of primary rhegmatogenous RD. Young patients and patients with proliferative vitreoretinopathy are at a higher risk for displacement.
背景视网膜脱离(RD)手术成功后视网膜血管旁出现高荧光线的原因是视网膜移位的发生。这可能归因于一些患者在手术后出现的视功能异常。患者和方法进行前瞻性介入研究,包括30例原发性孔源性RD患者中的30眼,这些患者通过平坦部玻璃体切除术和硅油填塞成功地进行了RD手术。所有患者均进行了术前和术后眼底自发荧光和光学相干断层扫描。术后随访3个月,进行最佳矫正视力测试和Amsler网格测试。结果纳入组的平均年龄为53.7±9.2岁,17例(56.7%)患者为男性。最常见的撕裂部位是颞上区(43.3%),其次是多发性外周区(23.33%)、上鼻区(13.3%)、颞下区(133%),16眼(53.3%,95%置信区间:36.7–70.0%)。有视网膜移位的患者明显比没有视网膜移位的年轻(P=0.019)与移位的发生有关(P=0.028)。变形症在移位患者中明显更常见(P<0.001)。结论原发性孔源性视网膜病变修复成功后发生视网膜移位的可能性很高。年轻患者和增殖性玻璃体视网膜病变患者发生移位的风险更高。
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引用次数: 0
Traumatic intraocular foreign bodies: correlation between size and structural damage 外伤性眼内异物:大小与结构损伤的关系
IF 0.2 Pub Date : 2023-04-01 DOI: 10.4103/ejos.ejos_16_23
H. Saigol, NajamNajam Iqbal, S. Akbar, Abdul Rauf, K. Chauhan, F. Ali, AbdulRehman Alvi, Madeeha Naeem, Muhammad Zeeshan
Background Ophthalmic trauma caused by intraocular foreign bodies (IOFBs) can impact visual prognosis by generating direct ocular structural damage. Factors bearing poor visual prognosis are related to size and velocity of IOFB, location in posterior segment with associated retinal detachment or endophthalmitis. Current study is aimed to evaluate size and location of IOFB and associated ocular structural damage. Methods In this retrospective study done at single tertiary center, patients injured by IOFBs were analyzed between January, 2010 to January, 2021 for ocular structural damage caused by size, velocity and location of impacted IOFB. All were assessed for corneal or scleral perforation and other structural damage due to IOFB. Location, route of retrieval and size of IOFB was measured. Results All 41 eyes were operated for removal of metallic IOFB. Corneal repair was done in 90.2% and scleral repair in 9.8% eyes. Hyphema cleared in 53.6% eyes. Traumatic cataract in 85.4% requiring phacoemulsification, preexisting aphakia (previous surgery) and siderosis was seen in 2.4% eyes. Retinal detachment was present in 14.6% and endophthalmitis in 4.9% eyes. Location of IOFB was on iris and lens in 2.4% each, with 19.5% impacted in retina and 75.6% were isolated in vitreous cavity. Small size IOFB was 58.3%, medium size was 29.3%, large size was 4.9% and very large size was 7.3%. No eye was deformed requiring evisceration of enucleation. Corneal or scleral repair, phacoemulsification, pars plana vitrectomy and intraocular foreign body removal as one stage procedure was done in each case. Intraocular lens implantation was done where sufficient anterior or posterior capsule was present. Conclusion Trauma caused by IOFB is commonly seen at workplace in young male laborers. It usually presents as corneal or scleral perforation, traumatic cataract, endophthalmitis and retinal detachment. Level of structural damage to ocular structures is dependent on the size, velocity and location of IOFB impaction. One stage surgical intervention for wound closure and IOFB should be considered for better surgical prognosis.
背景眼内异物(IOFBs)引起的眼外伤会产生直接的眼部结构损伤,从而影响视觉预后。视觉预后不良的因素与IOFB的大小和速度、视网膜脱离或眼内炎后段的位置有关。目前的研究旨在评估IOFB的大小和位置以及相关的眼部结构损伤。方法在这项在单一三级中心进行的回顾性研究中,分析了2010年1月至2021年1月期间因IOFB的大小、速度和位置而导致的眼部结构损伤。所有患者都评估了IOFB引起的角膜或巩膜穿孔和其他结构损伤。测量IOFB的位置、检索路线和大小。结果41眼均行金属性IOFB摘除术。角膜修复率90.2%,巩膜修复率9.8%。前房积血清除率为53.6%。85.4%的外伤性白内障需要超声乳化,2.4%的眼睛出现先前存在的无晶状体(先前的手术)和铁质沉着。视网膜脱离占14.6%,眼内炎占4.9%。IOFB位于虹膜和晶状体上各占2.4%,其中19.5%位于视网膜,75.6%位于玻璃体腔。小尺寸IOFB为58.3%,中尺寸为29.3%,大尺寸为4.9%,特大尺寸为7.3%。每个病例都进行了角膜或巩膜修复、超声乳化术、平坦部玻璃体切除术和眼内异物摘除术。在有足够的前囊或后囊的情况下进行人工晶状体植入。结论IOFB所致的创伤在青年男性劳动者的工作场所较为常见。通常表现为角膜或巩膜穿孔、外伤性白内障、眼内炎和视网膜脱离。眼部结构的结构损伤程度取决于IOFB撞击的大小、速度和位置。应考虑对伤口闭合和IOFB进行一期手术干预,以获得更好的手术预后。
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引用次数: 0
Evaluation of DMEK with secondary IOL implantation in cases of aphakic bullous keratopathy DMEK联合二次人工晶状体植入术治疗无晶状体大泡性角膜病变的疗效评价
IF 0.2 Pub Date : 2023-04-01 DOI: 10.4103/ejos.ejos_19_23
A. Galal, Moumen Seleet, Mohamed Kabeel, Ayman Swar
Context DMEK is used to treat corneal decompensation. This study focuses on the succcess and outcome of DMEK with and without secondary IOL implantation. Aims The purpose of our work is to evaluate Descemet membrane endothelial keratoplasty (DMEK) with secondary Intraocular lens (IOL) implantation in cases of aphakic bullous keratopathy with insufficient capsular support. Settings and design Pilot study. Methods and material This was a nonrandomized comparative prospective interventional case series where 11 eyes of 11 patients with aphakic bullous keratopathy secondary to complicated cataract surgery underwent DMEK with secondary IOL implantation using modified Yamane technique, and results were compared to 11 eyes of 11 patients underwent DMEK only. Statistical analysis used The statistical analysis was conducted using the Statistical Package for Social Sciences (SPSS 15.0.1 for windows; SPSS Inc, Chicago, IL, 2001). Results Both groups showed a high success rate (81.8%) with rebubbling required in 3 eyes in both groups. Both groups also showed significantly improved BCVA, decreased CCT and a decrease in donor graft ECD. Conclusions DMEK combined with secondary IOL implantation by modified Yamane technique appears to be a feasible method in managing aphakic bullos keratopathy with inadequate capsular support, and results are comparable to DMEK alone.
DMEK用于治疗角膜失代偿。本研究的重点是DMEK合并和不合并二次人工晶状体植入术的成功和结果。目的评价无晶状体大泡性角膜病变囊膜支持不足的患者行膜内皮角膜移植术(DMEK)联合继发性人工晶状体植入术的疗效。试验研究。方法和材料:本研究是一项非随机对照前瞻性介入病例系列研究,11例复杂性白内障术后继发无晶状体大泡性角膜病变患者的11只眼采用改良Yamane技术行DMEK合并二次人工晶状体植入术,并将结果与11例仅行DMEK的11只眼进行比较。统计分析采用SPSS 15.0.1 for windows;SPSS公司,芝加哥,伊利诺伊州,2001)。结果两组手术成功率均为81.8%,均有3只眼需要再泡。两组患者BCVA均显著改善,CCT降低,供体ECD降低。结论DMEK联合改良Yamane技术二次人工晶状体植入术是治疗无囊性大疱性角膜病变的可行方法,其效果与DMEK单独植入术相当。
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引用次数: 0
Long-term outcome of stab incision glaucoma surgery versus trabeculectomy surgery in the management of primary open angle glaucoma 原发性开角型青光眼手术与小梁切除术治疗的远期疗效
IF 0.2 Pub Date : 2023-04-01 DOI: 10.4103/ejos.ejos_95_22
W. Ebeid, A. A. Abdel Latif, A. Mousa, Mohammad Akram Awwad
Purpose To assess the long-term outcome of Stab incision glaucoma surgery (SIGS) and compare it with subscleral trabeculectomy (SST) in the management of open-angle glaucoma (OAG). Methods Twenty eyes of 20 OAG patients were randomly assigned into group 1: 10 patients underwent SIGS + Mitomycin C (MMC), and group 2: 10 patients underwent SST + MMC. The patients were followed-up over 2 years after surgery. Our outcome measures were: Postoperative intraocular pressure IOP, number of medications used, and postoperative complications. Results Twenty-four months postoperatively, the mean IOP was 13.78±2.05 mmHg in the SIGS group compared with preoperative IOP of 26.33±5.1 mmHg (P <0.001, paired t-test), and 14.38±4.56 mmHg in SST group compared with preoperative IOP of 30.13±7.51 mmHg (P <0.001, paired t-test). No significant differences in mean IOP between groups either preoperatively (P=0.15) or along follow-up (P=0.62 at last visit). The mean IOP drop from baseline was 12.56±5.00 mmHg (46.33±10.50%) in SIGS group and 15.75±8.22 mmHg (49.50±17.95%) in SST group (P=0.26). A significant decrease in the number of glaucoma medications was noted in the SIGSS group (P <0.001), in the SST group, the number decreased but was not statistically significant (P =0.120). Conclusion SIGS is comparable with SST in achieving long-term significant and maintained IOP reduction over up to 2 years, in addition to decreasing the number of antiglaucoma medications postoperatively. SIGS is recommended for surgical management of primary OAG as it has the advantage of being a faster, easier, less traumatic alternative to conventional SST with fewer complications.
目的评估Stab切口青光眼手术(SIGS)的长期疗效,并将其与巩膜下小梁切除术(SST)治疗开角型青光眼(OAG)的疗效进行比较。方法将20例OAG患者20眼随机分为1组:10例患者行SIGS + 丝裂霉素C(MMC)和第2:10组患者接受SST + MMC。术后随访2年以上。我们的结果指标是:术后眼压、用药次数和术后并发症。结果术后24个月,SIGS组的平均眼压为13.78±2.05毫米汞柱,而术前眼压为26.33±5.1毫米汞柱(P<0.001,配对t检验);SST组为14.38±4.56毫米汞柱。术前(P=0.15)或随访期间(上次访视时P=0.62),两组的平均眼压无显著差异。SIGS组平均眼压较基线下降12.56±5.00 mmHg(46.33±10.50%),SST组平均眼压下降15.75±8.22 mmHg(49.50±17.95%)(P=0.026),结论SIGS与SST相比,除了能减少术后抗青光眼药物的数量外,还能在长达2年的时间内实现长期显著且持续的眼压降低。SIGS被推荐用于原发性OAG的外科治疗,因为它具有比传统SST更快、更容易、创伤更小、并发症更少的优点。
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引用次数: 0
Posterior segment indications of handheld spectral domain optical coherence tomography in pediatric age group in a tertiary eye center in Egypt 手持式光谱域光学相干断层扫描后段指征在儿童年龄组在埃及三级眼科中心
IF 0.2 Pub Date : 2023-04-01 DOI: 10.4103/ejos.ejos_104_22
Gihan Shokier
Objective The aim of this study was to detect the posterior segment indications for the use of handheld optical coherence tomography in the pediatric age group. Patients and methods This was a retrospective observational study that included patients who were candidates for handheld spectral domain optical coherence tomography (HH-OCT) imaging for retinal or optic nerve (ON) diseases in Abo Elreesh hospital during the period from June 2018 to June 2022. The image, demographic, and clinical database of the included patients were reviewed. Data were tabulated using Microsoft Excel. Appropriate statistical methods were used to analyze and correlate the obtained data. Results A total of 189 patients were included in this study, comprising 109 (57.7%) male patients. The mean age was 7.2±3.9 (range: 0.2–16 years) years. Overall, 46 (24.3%) patients were less than 5 years of age (i.e. infants and preschool age). Patients who underwent HH-OCT scanning due to retinal causes (i.e. nystagmus, unexplained poor vision, uveitis, Coat’s disease, trauma, and high myopia) were 130 (68.8%) patients, whereas 59 (31.2%) patients were indicated due to ON disease (i.e. primary congenital glaucoma and juvenile open angle glaucoma, optic disc hyperemia, swelling or pallor, and cases of large physiological cupping). Conclusion HH-OCT is a noninvasive feasible image modality for evaluation of retina and ON in infants and young children. The lack of a normative database for retinal nerve fiber layer thickness and ON head parameters in the pediatric age group in the device available in our service is considered a limitation in its use for proper evaluation of different pathologies involving the ON.
目的探讨手持式光学相干断层扫描在儿童后段的适应症。这是一项回顾性观察性研究,纳入了2018年6月至2022年6月在Abo Elreesh医院进行手持式光谱域光学相干断层扫描(HH-OCT)成像的视网膜或视神经(ON)疾病患者。回顾纳入患者的影像、人口统计学和临床数据库。数据采用Microsoft Excel制表。采用适当的统计方法对所得数据进行分析和关联。结果共纳入189例患者,其中男性109例(57.7%)。平均年龄7.2±3.9岁(范围0.2 ~ 16岁)。总体而言,46例(24.3%)患者小于5岁(即婴儿和学龄前)。因视网膜原因(如眼球震颤、不明原因视力不佳、眼膜炎、科氏病、外伤、高度近视)行HH-OCT扫描的患者有130例(68.8%),而因ON疾病(如原发性先天性青光眼、青少年开角型青光眼、视盘充血、肿胀或苍白、大生理性火罐)行HH-OCT扫描的患者有59例(31.2%)。结论HH-OCT是一种评估婴幼儿视网膜和ON的无创、可行的成像方式。在我们提供的设备中,缺乏儿童年龄组视网膜神经纤维层厚度和ON头部参数的规范数据库,这被认为是限制其用于正确评估涉及ON的不同病理的限制。
{"title":"Posterior segment indications of handheld spectral domain optical coherence tomography in pediatric age group in a tertiary eye center in Egypt","authors":"Gihan Shokier","doi":"10.4103/ejos.ejos_104_22","DOIUrl":"https://doi.org/10.4103/ejos.ejos_104_22","url":null,"abstract":"Objective The aim of this study was to detect the posterior segment indications for the use of handheld optical coherence tomography in the pediatric age group. Patients and methods This was a retrospective observational study that included patients who were candidates for handheld spectral domain optical coherence tomography (HH-OCT) imaging for retinal or optic nerve (ON) diseases in Abo Elreesh hospital during the period from June 2018 to June 2022. The image, demographic, and clinical database of the included patients were reviewed. Data were tabulated using Microsoft Excel. Appropriate statistical methods were used to analyze and correlate the obtained data. Results A total of 189 patients were included in this study, comprising 109 (57.7%) male patients. The mean age was 7.2±3.9 (range: 0.2–16 years) years. Overall, 46 (24.3%) patients were less than 5 years of age (i.e. infants and preschool age). Patients who underwent HH-OCT scanning due to retinal causes (i.e. nystagmus, unexplained poor vision, uveitis, Coat’s disease, trauma, and high myopia) were 130 (68.8%) patients, whereas 59 (31.2%) patients were indicated due to ON disease (i.e. primary congenital glaucoma and juvenile open angle glaucoma, optic disc hyperemia, swelling or pallor, and cases of large physiological cupping). Conclusion HH-OCT is a noninvasive feasible image modality for evaluation of retina and ON in infants and young children. The lack of a normative database for retinal nerve fiber layer thickness and ON head parameters in the pediatric age group in the device available in our service is considered a limitation in its use for proper evaluation of different pathologies involving the ON.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70723352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of air versus sulfur hexafluoride tamponade in primary rhegmatogenous retinal detachment in phakic eyes 空气与六氟化硫填塞治疗原发性孔源性视网膜脱离的疗效
IF 0.2 Pub Date : 2023-04-01 DOI: 10.4103/ejos.ejos_2_23
A. Tabl, Mahrous Shaheen, Ahmed El Alim Mohamed, M. Tabl
Purpose To evaluate the outcomes of using air versus sulfur hexafluoride (SF6) gas tamponade in management of primary rhegmatogenous retinal detachment (RRD). Study design Retrospective case-series comparative study. Patients and methods We collected data from 120 patients in three tertiary university hospitals, that were diagnosed as primary RRD due to upper retinal break in the period from January 2021 to November 2022 and had undergone 23-G lens-sparing pars-plana vitrectomy with either air tamponade (Air group) or SF6 gas tamponade (SF6 group) and were followed up for 6 months. We analyzed the final visual outcomes between both groups. Results The mean age of the studied patients was 51±13 years (Air group=60 eyes, SF6 group=60 eyes). The mean axial length in Air group was 26.59±1.84 mm, the mean axial length was 26.46±1.49 mm in SF6 group. Best-corrected visual acuity was improved in both groups at the sixth month. In Air group 18.33% had recurrent RRD, while 10% in SF6 group. No significant difference regarding metamorphopsia was reported. Higher rate for cataract progression was noted among SF6 group. Conclusions Both Air and SF6 gas showed favorable results regarding the final visual outcome. Air is a less expensive tamponade with less timing for postoperative-prone positioning. Cataract progression was higher among SF6 group, however, the incidence of recurrent RRD was lower among SF6 group. Missed break was the primary cause for failed retinal reattachment.
目的评价空气与六氟化硫(SF6)气体填塞治疗原发性孔源性视网膜脱离(RRD)的疗效。研究设计回顾性病例系列比较研究。患者和方法我们收集了2021年1月至2022年11月在三所三级大学医院诊断为原发性视网膜上裂的120例患者的资料,这些患者于2021年1月至2022年11月期间接受了23-G保留晶状体的玻璃体切除术,采用空气填塞(air组)或SF6气体填塞(SF6组),随访6个月。我们分析了两组患者的最终视觉效果。结果患者平均年龄51±13岁(Air组60眼,SF6组60眼)。空气组平均轴长26.59±1.84 mm, SF6组平均轴长26.46±1.49 mm。6个月时两组最佳矫正视力均有改善。Air组复发率为18.33%,SF6组为10%。在变形方面无显著差异。SF6组白内障进展率较高。结论空气和SF6气体对最终的视觉效果都有良好的效果。空气是一种较便宜的填塞方法,术后俯卧位的时间较短。SF6组白内障进展明显,但RRD复发发生率较SF6组低。未断裂是视网膜再植失败的主要原因。
{"title":"Outcomes of air versus sulfur hexafluoride tamponade in primary rhegmatogenous retinal detachment in phakic eyes","authors":"A. Tabl, Mahrous Shaheen, Ahmed El Alim Mohamed, M. Tabl","doi":"10.4103/ejos.ejos_2_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_2_23","url":null,"abstract":"Purpose To evaluate the outcomes of using air versus sulfur hexafluoride (SF6) gas tamponade in management of primary rhegmatogenous retinal detachment (RRD). Study design Retrospective case-series comparative study. Patients and methods We collected data from 120 patients in three tertiary university hospitals, that were diagnosed as primary RRD due to upper retinal break in the period from January 2021 to November 2022 and had undergone 23-G lens-sparing pars-plana vitrectomy with either air tamponade (Air group) or SF6 gas tamponade (SF6 group) and were followed up for 6 months. We analyzed the final visual outcomes between both groups. Results The mean age of the studied patients was 51±13 years (Air group=60 eyes, SF6 group=60 eyes). The mean axial length in Air group was 26.59±1.84 mm, the mean axial length was 26.46±1.49 mm in SF6 group. Best-corrected visual acuity was improved in both groups at the sixth month. In Air group 18.33% had recurrent RRD, while 10% in SF6 group. No significant difference regarding metamorphopsia was reported. Higher rate for cataract progression was noted among SF6 group. Conclusions Both Air and SF6 gas showed favorable results regarding the final visual outcome. Air is a less expensive tamponade with less timing for postoperative-prone positioning. Cataract progression was higher among SF6 group, however, the incidence of recurrent RRD was lower among SF6 group. Missed break was the primary cause for failed retinal reattachment.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41977622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the outcome of limited protocol Ranibizumab injection in naïve choroidal neovascular membranes secondary to pathological myopia versus age-related macular degeneration 有限方案雷尼单抗注射naïve脉络膜新生血管膜继发病理性近视与年龄相关性黄斑变性的结果比较
IF 0.2 Pub Date : 2023-04-01 DOI: 10.4103/ejos.ejos_113_22
S. Fawzy, Mohammed Al-Tawab, Z. Ismail, W. Ebeid
Aim We aimed to compare the anatomical and visual response of newly diagnosed choroidal neovascularization (CNV) secondary to pathological myopia or age-related macular degeneration with relatively poor initial vision to treatment with three intravitreal injections of ranibizumab. Patients and methods This prospective, comparative study included 29 eyes of 29 patients newly diagnosed with subfoveal active CNV, either secondary to age-related macular degeneration (AMD-CNV, 15 eyes) or to pathological myopia, that is, myopic CNV (MCNV, 14 eyes). All patients had an initial best-corrected visual acuity (BCVA) equal to or worse than 1.00 Log Mar. Patients received three intravitreal injections of 0.50 mg ranibizumab on a monthly basis. Patients were evaluated before injections and one month after each injection for BCVA and optical coherence tomography-measured retinal parameters: central macular thickness, total volume, and average thickness (AT). Amsler’s chart was used to detect scotomas and metamorphopsias. Results One month after the three injections, a significant improvement was noted in the two groups in central macular thickness, total volume, and AT. The improvement was significantly better in AT of the AMD group. The mean BCVA improved significantly in the AMD group only as patients either improved or remained stationary, whereas in the MCNV group, 21% of patients deteriorated, which affected the significance of the overall mean of improvement (P=0.7823); the difference in the overall mean was insignificant. Despite that, almost half of the patients in each group had their visual acuity improved by an average of 9.5 letters in AMD and 10.7 in MCNV. Conclusion Naïve AMD-CNV and MCNV of initially poor VA can get significant improvement in all optical coherence tomography-measured retinal parameters following a three-injection course of ranibizumab on a monthly basis. VA improvement is more predictable in AMD, as no patients deteriorated after the injections, yet the overall difference in VA improvement between groups was insignificant.
我们的目的是比较新诊断的脉络膜新生血管(CNV)继发于病理性近视或年龄相关性黄斑变性,初始视力相对较差,与三次玻璃体内注射雷尼单抗治疗的解剖学和视觉反应。患者和方法本前瞻性比较研究纳入29例新诊断的中央凹下活动性CNV患者的29只眼,继发于年龄相关性黄斑变性(AMD-CNV, 15只眼)或病理性近视,即近视性CNV (MCNV, 14只眼)。所有患者的初始最佳矫正视力(BCVA)等于或低于1.00 Log 3。患者每月接受三次0.50 mg雷尼单抗玻璃体内注射。在注射前和每次注射后1个月评估患者的BCVA和光学相干断层扫描测量的视网膜参数:中央黄斑厚度、总体积和平均厚度(AT)。用Amsler图检测暗斑和变形。结果三次注射后1个月,两组黄斑中央厚度、总积、AT均有明显改善。AMD组AT改善明显更好。AMD组的平均BCVA只有在患者改善或保持平稳时才显著改善,而MCNV组21%的患者恶化,这影响了总体平均改善的显著性(P=0.7823);总体平均值的差异不显著。尽管如此,两组中几乎有一半的患者的视力在AMD和MCNV中平均提高了9.5个字母和10.7个字母。结论Naïve初始VA较差的AMD-CNV和MCNV在每月三次注射雷尼单抗后,所有光学相干断层扫描测量的视网膜参数均有显著改善。AMD的VA改善更可预测,因为注射后没有患者恶化,但两组之间VA改善的总体差异不显著。
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引用次数: 0
Study of corneal endothelial cell layer 3 months after Descemet membrane endothelial keratoplasty Descemet膜内皮角膜移植术后3个月角膜内皮细胞层的研究
IF 0.2 Pub Date : 2023-04-01 DOI: 10.4103/ejos.ejos_90_22
Amira Kamhawy, O. Salem, Yasser El Zankalony, A. Ebeid
Background To study the endothelial cell layer 3 months after Descemet membrane endothelial keratoplasty (DMEK) using specular microscopy to provide data about the endothelial cell density (ECD), endothelial cell loss (ECL) percentage, and changes in endothelial cell shape (hexagonality) and size [coefficient of variation (CV)] and to study the factors causing these changes in endothelial cell layer after DMEK. Patients and methods This study included 20 patients investigated by specular microscopy 3 months after DMEK. We discuss the postoperative ECD, factors that affect the ECD, factors that affect hexagonality and CV, visual outcome, and advantages of DMEK. The study was approved by the ethics committee of Ain Shams University. Results This study showed that the mean ECD postoperative was 1664.80 cells/mm2, with mean ECL of 34.67%. This cell loss increased in cases of difficult graft unfolding. Donor age and preservation time had no effect on postoperative ECD. A percentage decrease in hexagonal cells and a percentage increase in CV were noticed in cases that received grafts from donors with history of diabetes mellitus. Postoperative ECD and hexagonal cell percentage had no correlation with central corneal thickness in this study. Conclusion DMEK results in significant improvement of postoperatively visual acuity (VA). Advantages of DMEK like no corneal sutures, short recovery time, less cylindrical aberration, decreased incidence of graft rejection, and good visual outcome make it the best choice to treat eyes with corneal endothelial dysfunction.
背景应用镜面显微镜研究后弹力膜内皮角膜移植术(DMEK)后3个月的内皮细胞层,以及内皮细胞形状(六边形)和大小的变化[变异系数(CV)],并研究DMEK后引起内皮细胞层这些变化的因素。患者和方法本研究包括20例DMEK术后3个月进行镜面显微镜检查的患者。我们讨论了术后ECD、影响ECD的因素、影响六边形和CV的因素、视觉结果以及DMEK的优势。这项研究得到了艾因沙姆斯大学伦理委员会的批准。结果术后平均ECD为1664.80个细胞/mm2,平均ECL为34.67%。供体年龄和保存时间对术后ECD无影响。在接受有糖尿病病史的供体移植物的病例中,六边形细胞的百分比减少,CV的百分比增加。在本研究中,术后ECD和六边形细胞百分比与角膜中央厚度无关。结论DMEK能显著提高术后视力。DMEK具有无角膜缝线、恢复时间短、柱面像差少、移植物排斥反应发生率低、视觉效果好等优点,是治疗角膜内皮功能障碍的最佳选择。
{"title":"Study of corneal endothelial cell layer 3 months after Descemet membrane endothelial keratoplasty","authors":"Amira Kamhawy, O. Salem, Yasser El Zankalony, A. Ebeid","doi":"10.4103/ejos.ejos_90_22","DOIUrl":"https://doi.org/10.4103/ejos.ejos_90_22","url":null,"abstract":"Background To study the endothelial cell layer 3 months after Descemet membrane endothelial keratoplasty (DMEK) using specular microscopy to provide data about the endothelial cell density (ECD), endothelial cell loss (ECL) percentage, and changes in endothelial cell shape (hexagonality) and size [coefficient of variation (CV)] and to study the factors causing these changes in endothelial cell layer after DMEK. Patients and methods This study included 20 patients investigated by specular microscopy 3 months after DMEK. We discuss the postoperative ECD, factors that affect the ECD, factors that affect hexagonality and CV, visual outcome, and advantages of DMEK. The study was approved by the ethics committee of Ain Shams University. Results This study showed that the mean ECD postoperative was 1664.80 cells/mm2, with mean ECL of 34.67%. This cell loss increased in cases of difficult graft unfolding. Donor age and preservation time had no effect on postoperative ECD. A percentage decrease in hexagonal cells and a percentage increase in CV were noticed in cases that received grafts from donors with history of diabetes mellitus. Postoperative ECD and hexagonal cell percentage had no correlation with central corneal thickness in this study. Conclusion DMEK results in significant improvement of postoperatively visual acuity (VA). Advantages of DMEK like no corneal sutures, short recovery time, less cylindrical aberration, decreased incidence of graft rejection, and good visual outcome make it the best choice to treat eyes with corneal endothelial dysfunction.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42462257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alteration in corneal topography asymmetry indices following corneal refractive surgery 角膜屈光手术后角膜地形图不对称指数的变化
IF 0.2 Pub Date : 2023-04-01 DOI: 10.4103/ejos.ejos_119_22
Tamer I Abdelhalim, Osama A. Sorour, Mohamed Elkadim, D. Tadros
Purpose We aimed to follow up corneal refractive asymmetry index changes following refractive surgery for cornea after correction of low-grade myopia and to determine which technique causes marked affection of the indices. Patients and methods This prospective study conducted from October 2020 to December 2021 included two groups of patients, the photorefractive keratectomy (PRK) group and the laser in-situ keratomileusis (LASIK) group. Every patient in each group had to follow a schedule of visits after surgery for the next day, 1 week, 1 month, and after 3 months. Patients who failed to follow this schedule were excluded from the study. Results The PRK group contained 42 eyes with a mean uncorrected visual acuity that improved significantly, corneal power (K-reading) and pupil center thickness reduced significantly. Surface variance index, central keratoconus index, and height decentration index did not change significantly. Vertical asymmetry index and minimum radius of curvature (Rmin) increased significantly while height asymmetry index decreased significantly. Our LASIK group contained 40 eyes that underwent changes similar to those in the PRK group regarding uncorrected visual acuity, the K-reading, and the pupil center thickness. The surface variance index, vertical asymmetry index, and height asymmetry index, height decentration index and Rmin increased significantly while the central keratoconus index decreased significantly. The keratoconus index reduced significantly in both groups. Conclusion The PRK is a more conservative technique than the LASIK technique regarding the affection of corneal asymmetry indices.
目的:我们旨在跟踪低度近视矫正后角膜屈光手术后角膜屈光不对称指数的变化,并确定哪种技术会对指数产生显著影响。患者和方法这项前瞻性研究于2020年10月至2021年12月进行,包括两组患者,屈光性角膜切削术(PRK)组和激光原位角膜磨镶术(LASIK)组。每组患者都必须遵循手术后第二天、1周、1个月和3个月的就诊时间表。未能遵循此时间表的患者被排除在研究之外。结果PRK组42眼,平均裸眼视力显著提高,角膜屈光度(K读数)和瞳孔中心厚度显著降低。表面变异指数、圆锥角膜中心指数和高度偏心指数无明显变化。垂直不对称指数和最小曲率半径(Rmin)显著增加,而高度不对称指数显著降低。我们的LASIK组包括40只眼睛,这些眼睛在裸眼视力、K读数和瞳孔中心厚度方面发生了与PRK组相似的变化。表面变异指数、垂直不对称指数、身高不对称指数、高度偏心指数和Rmin显著增加,而中央圆锥角膜指数显著下降。圆锥角膜指数在两组中均显著降低。结论就角膜不对称性指标的影响而言,PRK技术比LASIK技术更为保守。
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引用次数: 0
Spectacle measurements versus contact lens measurements of the angle of deviation in myopic patients with strabismus 近视斜视患者的眼镜测量与隐形眼镜测量偏差角的比较
IF 0.2 Pub Date : 2023-04-01 DOI: 10.4103/ejos.ejos_82_22
D. Hassanein, Ahmed Awadein, Aya Youssef, Gihan Shokier
Purpose To compare the measurements of the angle of deviation through spectacles versus contact lenses and with the theoretically calculated angle. Patients and methods A total of 20 patients with comitant strabismus, more than 20 PD with spectacles, associated with bilateral myopia (spherical equivalent >1 D in both eyes) were included. Angle of deviation was measured using prism and cover test with spectacles and with contact lenses fitted according to the cycloplegic refraction and refined by subjective refraction. Agreements between the measurements obtained with contact lenses and those obtained with spectacles as well as the theoretically calculated angle were analyzed. Results The mean age was 15.6±10.9 years. Average spherical equivalent was −9.1±4.2 D. Measurements obtained with contact lenses were significantly lower than those with spectacles (P<0.001) with coefficient of variation of 27.7%, indicating poor agreement of both measurements. Limits of agreement in Bland–Altman plots were more than 9 PD ([INLINE:1] ± 2 s, −8.8 to 6 PD). The agreement was lower with larger angles. Measurements obtained with contact lenses were significantly lower than theoretical angles (P=0.002) but coefficient of variation between both measurements was 8.8%, indicating good agreement of measurements. There was little systematic or proportionate bias between the contact lens measurements and the theoretical angle. Conclusions Contact lens measurements were significantly lower than spectacle measurements in myopic patients. The contact lens measurements were in good agreement with the theoretically calculated angle. This overestimation of the angle with spectacles might be responsible for overcorrection of myopic patients with exotropia after surgery.
目的比较通过眼镜和隐形眼镜测量的偏转角,并与理论计算的偏转角进行比较。患者和方法共纳入20例共同性斜视患者,20例戴眼镜的PD以上,伴有双侧近视(双眼球面当量>1D)。使用棱镜和遮盖物测试测量偏转角,眼镜和隐形眼镜根据睫状肌屈光度安装,并通过主观屈光度进行细化。分析了用隐形眼镜获得的测量结果与用眼镜获得的结果之间的一致性以及理论计算的角度。结果平均年龄15.6±10.9岁。平均球面当量为−9.1±4.2 D。使用隐形眼镜获得的测量值显著低于使用眼镜获得的值(P<0.001),变异系数为27.7%,表明两种测量值的一致性较差。Bland–Altman地块的一致性限制超过9 PD([INLINE:1] ± 2. s、 −8.8至6 PD)。角度越大,协议越低。用隐形眼镜获得的测量值明显低于理论角度(P=0.002),但两种测量值之间的变异系数为8.8%,表明测量值一致性良好。隐形眼镜的测量值和理论角度之间几乎没有系统或成比例的偏差。结论近视患者的隐形眼镜测量值明显低于眼镜测量值。隐形眼镜的测量值与理论计算的角度非常一致。这种对眼镜角度的高估可能是近视外斜视患者术后矫正过度的原因。
{"title":"Spectacle measurements versus contact lens measurements of the angle of deviation in myopic patients with strabismus","authors":"D. Hassanein, Ahmed Awadein, Aya Youssef, Gihan Shokier","doi":"10.4103/ejos.ejos_82_22","DOIUrl":"https://doi.org/10.4103/ejos.ejos_82_22","url":null,"abstract":"Purpose To compare the measurements of the angle of deviation through spectacles versus contact lenses and with the theoretically calculated angle. Patients and methods A total of 20 patients with comitant strabismus, more than 20 PD with spectacles, associated with bilateral myopia (spherical equivalent >1 D in both eyes) were included. Angle of deviation was measured using prism and cover test with spectacles and with contact lenses fitted according to the cycloplegic refraction and refined by subjective refraction. Agreements between the measurements obtained with contact lenses and those obtained with spectacles as well as the theoretically calculated angle were analyzed. Results The mean age was 15.6±10.9 years. Average spherical equivalent was −9.1±4.2 D. Measurements obtained with contact lenses were significantly lower than those with spectacles (P<0.001) with coefficient of variation of 27.7%, indicating poor agreement of both measurements. Limits of agreement in Bland–Altman plots were more than 9 PD ([INLINE:1] ± 2 s, −8.8 to 6 PD). The agreement was lower with larger angles. Measurements obtained with contact lenses were significantly lower than theoretical angles (P=0.002) but coefficient of variation between both measurements was 8.8%, indicating good agreement of measurements. There was little systematic or proportionate bias between the contact lens measurements and the theoretical angle. Conclusions Contact lens measurements were significantly lower than spectacle measurements in myopic patients. The contact lens measurements were in good agreement with the theoretically calculated angle. This overestimation of the angle with spectacles might be responsible for overcorrection of myopic patients with exotropia after surgery.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48760552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of the Egyptian Ophthalmological Society
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