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Anterior segment-optical coherence tomography for evaluation of the epithelium thickness profile in keratoconic corneas and normal corneas 前节段-光学相干断层扫描评价角膜锥形角膜和正常角膜上皮厚度
IF 0.2 Q4 OPHTHALMOLOGY Pub Date : 2021-01-01 DOI: 10.4103/ejos.ejos_47_21
Soha Eltohamy
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引用次数: 1
Anterior lamellar recession with and without blepharoplasty in upper eyelid cicatricial entropion 上睑瘢痕性内翻术后前板层退缩的观察
IF 0.2 Q4 OPHTHALMOLOGY Pub Date : 2021-01-01 DOI: 10.4103/ejos.ejos_54_21
Kareem B. Elessawy, AlshymaaM Elnagar, H. Nasr, S. Abdelbaky
{"title":"Anterior lamellar recession with and without blepharoplasty in upper eyelid cicatricial entropion","authors":"Kareem B. Elessawy, AlshymaaM Elnagar, H. Nasr, S. Abdelbaky","doi":"10.4103/ejos.ejos_54_21","DOIUrl":"https://doi.org/10.4103/ejos.ejos_54_21","url":null,"abstract":"","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70723660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lensectomy with anterior vitrectomy plus goniosynechialysis followed by iris-claw intraocular-lens implantation in microspherophakia-induced glaucoma 晶状体切除术+前玻璃体切除术+巩膜粘连术后虹膜-爪形人工晶状体植入术治疗微球性青光眼
IF 0.2 Q4 OPHTHALMOLOGY Pub Date : 2021-01-01 DOI: 10.4103/ejos.ejos_51_21
Hazem Helmy
{"title":"Lensectomy with anterior vitrectomy plus goniosynechialysis followed by iris-claw intraocular-lens implantation in microspherophakia-induced glaucoma","authors":"Hazem Helmy","doi":"10.4103/ejos.ejos_51_21","DOIUrl":"https://doi.org/10.4103/ejos.ejos_51_21","url":null,"abstract":"","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70723502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of the efficiency and safety of subconjunctival triamcinolone acetonide in macular edema 结膜下曲安奈德治疗黄斑水肿的有效性和安全性研究
IF 0.2 Q4 OPHTHALMOLOGY Pub Date : 2021-01-01 DOI: 10.4103/ejos.ejos_47_20
Abdellaoui Taoufik, Chaoui Yassmine, M. Yassine, Mouzari Yassine, E. Fouad, R. Karim, O. Abdelbarre
Purpose To evaluate through a prospective study the efficiency and safety of triamcinolone in subconjunctival injection on macular edema (ME), in the short and medium term. Patients and methods All the patients included in the study underwent ophthalmologic examination and optic coherence tomography of the macula. The injection of 0.2–0.3 ml (8–12 mg) of triamcinolone was done in the subconjunctival space. We evaluated its efficiency by measuring the best-corrected visual acuity and the central macular thickness at 1, 3, and 6 months. Safety was evaluated by following up the intraocular pressure; the presence or absence of cataract and conjunctival complications at 1, 3, and 6 months; and the glycemic control. Results A total of 44 eyes (36 patients) were included. The overall best-corrected visual acuity and central macular thickness improved after injection. Overall, 67% of diabetic patients required reinjection at the third month. In the cases of inflammatory ME (uveitis and Irvine–Gass), the evolution has remained stable for 6 months after a single injection. No significant variation in intraocular pressure was noted after 1 month (P=0.38), after 3 months (P=0.20), or after 6 months (P=0.13). However, four patients developed ocular hypertension (10 mmHg or more above baseline), which has been well controlled with local monotherapy. Overall, 9.5% of phakic patients developed a cataract at the control of the sixth month. The change in glycated hemoglobin before and after the injection was not significant (P=0.84). Conclusion Subconjunctival triamcinolone acetonide seems to be an interesting and well-tolerated alternative therapy of ME in the short and medium term.
目的通过前瞻性研究评价曲安奈德结膜下注射治疗黄斑水肿(ME)的中短期疗效和安全性。患者和方法所有纳入研究的患者都接受了眼科检查和黄斑光学相干断层扫描。0.2–0.3的注射 毫升(8-12 mg)曲安奈德。我们通过测量1、3和6个月时的最佳矫正视力和中心黄斑厚度来评估其效率。通过随访眼压来评估安全性;在第1、3和6个月时是否存在白内障和结膜并发症;以及血糖控制。结果共纳入44眼(36例)。注射后,整体最佳矫正视力和中央黄斑厚度有所改善。总的来说,67%的糖尿病患者在第三个月需要重新注射。在炎症性ME(葡萄膜炎和Irvine–Gass)的病例中,单次注射后,进化在6个月内保持稳定。术后1个月(P=0.38)、3个月(P=0.020)或6个月(P=0.13)眼压无明显变化。然而,有4名患者出现高眼压(高于基线10毫米汞柱或以上),局部单药治疗已很好地控制了这种情况。总的来说,9.5%的有晶状体眼患者在第六个月时出现白内障。糖化血红蛋白在注射前后变化不显著(P=0.84)。结论结膜下曲安奈德是一种有趣且耐受性良好的中短期ME替代疗法。
{"title":"Study of the efficiency and safety of subconjunctival triamcinolone acetonide in macular edema","authors":"Abdellaoui Taoufik, Chaoui Yassmine, M. Yassine, Mouzari Yassine, E. Fouad, R. Karim, O. Abdelbarre","doi":"10.4103/ejos.ejos_47_20","DOIUrl":"https://doi.org/10.4103/ejos.ejos_47_20","url":null,"abstract":"Purpose To evaluate through a prospective study the efficiency and safety of triamcinolone in subconjunctival injection on macular edema (ME), in the short and medium term. Patients and methods All the patients included in the study underwent ophthalmologic examination and optic coherence tomography of the macula. The injection of 0.2–0.3 ml (8–12 mg) of triamcinolone was done in the subconjunctival space. We evaluated its efficiency by measuring the best-corrected visual acuity and the central macular thickness at 1, 3, and 6 months. Safety was evaluated by following up the intraocular pressure; the presence or absence of cataract and conjunctival complications at 1, 3, and 6 months; and the glycemic control. Results A total of 44 eyes (36 patients) were included. The overall best-corrected visual acuity and central macular thickness improved after injection. Overall, 67% of diabetic patients required reinjection at the third month. In the cases of inflammatory ME (uveitis and Irvine–Gass), the evolution has remained stable for 6 months after a single injection. No significant variation in intraocular pressure was noted after 1 month (P=0.38), after 3 months (P=0.20), or after 6 months (P=0.13). However, four patients developed ocular hypertension (10 mmHg or more above baseline), which has been well controlled with local monotherapy. Overall, 9.5% of phakic patients developed a cataract at the control of the sixth month. The change in glycated hemoglobin before and after the injection was not significant (P=0.84). Conclusion Subconjunctival triamcinolone acetonide seems to be an interesting and well-tolerated alternative therapy of ME in the short and medium term.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"114 1","pages":"13 - 20"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49510440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of deep anterior lamellar keratoplasty for anterior corneal stromal pathology 深前板层角膜移植术对角膜前基质病理学的评价
IF 0.2 Q4 OPHTHALMOLOGY Pub Date : 2021-01-01 DOI: 10.4103/ejos.ejos_50_20
Aya Hashish, Eman A. Awad, D. Sabry, Hatem El-Awady, M. El-Metwally
Settings This study was conducted in Mansoura Ophthalmic Center, Mansoura University, Egypt, during the period from January 2018 to January 2019. Purpose This study aimed to evaluate the visual outcomes, topographic features, endothelial cell densities (ECD), and complications of deep anterior lamellar keratoplasty using big-bubble technique (BB-DALK) in different corneal stromal pathologies. Patients and methods This was a prospective, interventional study that included 24 eyes of 24 patients having corneal stromal pathologies, not involving Descemet membrane (DM) and endothelium. The primary outcome measures were the clinical, visual, and topographic outcomes (uncorrected visual acuity, best-corrected visual acuity, K1, and K2) throughout the follow-up period, whereas the secondary outcome measures were the refractive outcomes, central corneal thickness, ECD, and intraoperative and postoperative complications. Results A total of 21 (87.5%) patients underwent uneventful BB-DALK, and three (12.5%) cases were complicated by intraoperative DM microperforation who developed DM detachment and double anterior chamber (AC) postoperatively. One of them resolved spontaneously and the other two cases required intracameral air injection. Uncorrected visual acuity improved from 1.55±0.26 (logarithm of minimum angle of resolution) preoperatively to 0.63±0.2 1 year postoperatively (P<0.001) and best-corrected visual acuity improved from 1.08±0.11 (logarithm of minimum angle of resolution) to 0.30±0.12 (P=0.017). Refractive cylinder improved from −7.79±1.75 to −2.85±2.01 at 12 months of follow-up (P=0.007). Average K reading changed from 60.00±7.77 preoperatively to 43.43±2.98 postoperatively (P<0.001). Total ECD was 2248.08±431.13 by the end of the first year, with a mean of 8.2% endothelial cell loss. Loosening of the sutures occurred in five (20.8%) eyes between third and sixth months postoperatively. Urrets-Zavalia syndrome occurred in one of the two cases who were complicated with postoperative double AC and required intracameral air injection. Conclusions BB-DALK is an effective and safe technique for treatment of different corneal stromal pathologies sparing endothelium and DM.
背景本研究于2018年1月至2019年1月在埃及曼苏拉大学曼苏拉眼科中心进行。目的本研究旨在评估大气泡技术(BB-DALK)在不同角膜基质病变中进行深前板层角膜移植术的视觉效果、地形特征、内皮细胞密度(ECD)和并发症。患者和方法这是一项前瞻性的介入性研究,包括24名患有角膜基质病变的患者中的24眼,不涉及后弹力膜(DM)和内皮。主要结果指标是整个随访期间的临床、视觉和地形结果(裸眼视力、最佳矫正视力K1和K2),而次要结果指标是屈光结果、角膜中央厚度、ECD以及术中和术后并发症。结果21例(87.5%)患者顺利进行了BB-DALK,3例(12.5%)患者术中并发DM微穿孔,术后出现DM脱离和双前房(AC)。其中一例自行消退,另外两例需要前房内空气注射。未矫正视力从术前的1.55±0.26(最小分辨角的对数)提高到术后1年的0.63±0.2(P<0.001),最佳矫正视力从1.08±0.11(最小分辨角度的对数)改善到0.30±0.12(P=0.017)。随访12个月时,屈光柱从−7.79±1.75提高到−2.85±2.01(P=0.007)术前为60.00±7.77,术后为43.43±2.98(P<0.001)。到第一年年底,总ECD为2248.08±431.13,平均内皮细胞损失8.2%。术后第三个月至第六个月,有五只(20.8%)眼睛出现缝线松动。Urrets-Zavalia综合征发生在两例患者中的一例,该患者术后并发双AC,需要前房内空气注射。结论BB-DALK是一种有效、安全的治疗不同角膜基质病变的方法,可保留内皮细胞和糖尿病。
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引用次数: 0
Comparative study of conventional versus torsional phacoemulsification in management of hard nucleus 常规与扭转超声乳化术治疗硬核的比较研究
IF 0.2 Q4 OPHTHALMOLOGY Pub Date : 2021-01-01 DOI: 10.4103/ejos.ejos_43_20
Shereen Salman, Mervat Mourad, Rafek ElGhazawy, Rafaat Rihan
Background Phacoemulsification acoenergy and shortening the phacotime can decrease this risk. Aim The aim of this work is to compare the safety and the efficiency of phacoemulsification using conventional and torsional ultrasound modalities for hard nucleus cataracts. Settings and design This was a prospective randomized interventional study. Patients and methods A total of 30 eyes of 29 patients having hard nuclear cataract (grades IV and V) were divided into two groups. Group A included 15 eyes whose cataract was operated on by conventional phacoemulsification using the Infiniti machine. Group B included 15 eyes whose cataract was operated on by torsional phacoemulsification using the OZil technology of the Infiniti machine. Intraoperative ultrasound time and cumulative dissipated energy were recorded. Postoperative central corneal thickness (CCT) was measured at days 1, 7, and 30, and specular microscopy was done at 1 month. Statistical analysis The collected data were coded, tabulated, and statistically analyzed. Results The mean ultrasound time and cumulative dissipated energy and the amount of irrigating fluid were significantly higher in group A. There was a highly significant decrease in endothelial cell count (ECC) in both groups. ECC was significantly lower in the conventional group than in the torsional group at 1 month postoperatively. CCT in both groups was significantly increased at day 1 and then decreased at 1 week and 1 month but was still significantly higher than the preoperative level. CCT became higher in the conventional group than in the torsional group at all follow-up times, but this was significant only at day 1 and week 1 and not significant at 1 month. Conclusion Both ultrasound modalities can be used in hard nucleus phacoemulsification. However, the torsional ultrasound proved to be safer. The choice between these technologies is of particular importance when operating eyes with low ECC.
背景:超声乳化术能减少能量和缩短超声时间可以降低这种风险。目的比较常规超声和扭转超声对硬核白内障超声乳化术的安全性和有效性。这是一项前瞻性随机干预性研究。患者与方法将29例硬核性白内障(IV级、V级)患者30只眼分为两组。A组15只眼采用Infiniti机器行常规超声乳化白内障手术。B组15眼采用Infiniti机器的OZil技术行扭转超声乳化白内障手术。记录术中超声时间和累计耗散能量。术后第1天、第7天和第30天测量角膜中央厚度(CCT),第1个月进行镜面显微镜检查。对收集到的数据进行编码、制表和统计分析。结果a组平均超声时间、累积耗散能和灌洗液量均显著高于a组,内皮细胞计数(ECC)均显著降低。术后1个月,常规组的ECC明显低于扭转组。两组患者CCT均在第1天显著升高,第1周和第1个月显著降低,但仍显著高于术前水平。在所有随访时间,常规组的CCT均高于扭转组,但这仅在第1天和第1周显著,1个月时不显著。结论两种超声方式均可用于硬核超声乳化术。然而,扭转超声被证明是更安全的。当操作低ECC的眼睛时,这些技术之间的选择尤为重要。
{"title":"Comparative study of conventional versus torsional phacoemulsification in management of hard nucleus","authors":"Shereen Salman, Mervat Mourad, Rafek ElGhazawy, Rafaat Rihan","doi":"10.4103/ejos.ejos_43_20","DOIUrl":"https://doi.org/10.4103/ejos.ejos_43_20","url":null,"abstract":"Background Phacoemulsification acoenergy and shortening the phacotime can decrease this risk. Aim The aim of this work is to compare the safety and the efficiency of phacoemulsification using conventional and torsional ultrasound modalities for hard nucleus cataracts. Settings and design This was a prospective randomized interventional study. Patients and methods A total of 30 eyes of 29 patients having hard nuclear cataract (grades IV and V) were divided into two groups. Group A included 15 eyes whose cataract was operated on by conventional phacoemulsification using the Infiniti machine. Group B included 15 eyes whose cataract was operated on by torsional phacoemulsification using the OZil technology of the Infiniti machine. Intraoperative ultrasound time and cumulative dissipated energy were recorded. Postoperative central corneal thickness (CCT) was measured at days 1, 7, and 30, and specular microscopy was done at 1 month. Statistical analysis The collected data were coded, tabulated, and statistically analyzed. Results The mean ultrasound time and cumulative dissipated energy and the amount of irrigating fluid were significantly higher in group A. There was a highly significant decrease in endothelial cell count (ECC) in both groups. ECC was significantly lower in the conventional group than in the torsional group at 1 month postoperatively. CCT in both groups was significantly increased at day 1 and then decreased at 1 week and 1 month but was still significantly higher than the preoperative level. CCT became higher in the conventional group than in the torsional group at all follow-up times, but this was significant only at day 1 and week 1 and not significant at 1 month. Conclusion Both ultrasound modalities can be used in hard nucleus phacoemulsification. However, the torsional ultrasound proved to be safer. The choice between these technologies is of particular importance when operating eyes with low ECC.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"114 1","pages":"1 - 12"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47522654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Combined femtosecond laser-assisted intrastromal corneal ring segments implantation and corneal collagen cross-linking for treatment of pellucid-like keratoconus 飞秒激光辅助层内角膜环段植入联合角膜胶原交联治疗透明性圆锥角膜
IF 0.2 Q4 OPHTHALMOLOGY Pub Date : 2020-10-01 DOI: 10.4103/ejos.ejos_48_20
M. Abozaid
Purpose To evaluate the safety and efficacy of combined femtosecond laser-assisted intrastromal corneal ring segments implantation plus accelerated transepithelial corneal collagen cross-linking (ATE-CXL) in cases of pellucid-like keratoconus (PLK). Patients and methods This retrospective study included 25 eyes of 13 patients with PLK. Cases were divided into two groups: group 1 consisted of 13 eyes (seven patients) that had been treated by femtosecond laser-assisted Kerarings implantation and ATE-CXL in the same session, whereas group 2 included 12 eyes (six patients) that had been treated with ATE-CXL alone. Results After 1 year of surgery, the mean uncorrected visual acuity (UCVA) of group 1 improved from 0.94±23 (logMAR) to 0.73±18, whereas the mean best-corrected visual acuity improved from 0.75±16 to 0.49±0.22. The mean preoperative maximum keratometry (Kmax) was 65.23±5.03 D, whereas the mean postoperative Kmax was 53.92±4.21 D. However, in group 2, the preoperative mean UCVA was 0.63±0.31 and the postoperative UCVA was 0.55±0.29, whereas the mean best-corrected visual acuity changed from 0.31±0.26 to 0.23±0.19. The mean preoperative Kmax was 51.38±3.73 D, whereas the mean postoperative Kmax was 48.43±2.98 D. Conclusion Combined femtosecond laser-assisted Kerarings implantation and ATE-CXL is safe and effective in the treatment of PLK.
目的评价飞秒激光辅助层内角膜环段植入联合加速角膜胶原交联(ATE-CXL)治疗透明性圆锥角膜(PLK)的安全性和有效性。患者和方法本回顾性研究包括13例PLK患者的25眼。病例分为两组:第1组包括13只眼睛(7名患者),在同一疗程中接受了飞秒激光辅助角膜缘植入和ATE-CXL治疗,而第2组包括12只眼睛(6名患者)单独接受了ATE-CXL的治疗。结果术后1年,1组的平均裸眼视力(UCVA)从0.94±23(logMAR)提高到0.73±18,而平均最佳矫正视力从0.75±16提高到0.49±0.22。平均术前最大角膜曲率(Kmax)为65.23±5.03D,而平均术后Kmax为53.92±4.21D。然而,在第2组中,术前平均UCVA为0.63±0.31,术后UCVA为0.55±0.29,而平均最佳矫正视力从0.31±0.26变为0.23±0.19。术前平均Kmax为51.38±3.73D,术后平均Kmax则为48.43±2.98D。
{"title":"Combined femtosecond laser-assisted intrastromal corneal ring segments implantation and corneal collagen cross-linking for treatment of pellucid-like keratoconus","authors":"M. Abozaid","doi":"10.4103/ejos.ejos_48_20","DOIUrl":"https://doi.org/10.4103/ejos.ejos_48_20","url":null,"abstract":"Purpose To evaluate the safety and efficacy of combined femtosecond laser-assisted intrastromal corneal ring segments implantation plus accelerated transepithelial corneal collagen cross-linking (ATE-CXL) in cases of pellucid-like keratoconus (PLK). Patients and methods This retrospective study included 25 eyes of 13 patients with PLK. Cases were divided into two groups: group 1 consisted of 13 eyes (seven patients) that had been treated by femtosecond laser-assisted Kerarings implantation and ATE-CXL in the same session, whereas group 2 included 12 eyes (six patients) that had been treated with ATE-CXL alone. Results After 1 year of surgery, the mean uncorrected visual acuity (UCVA) of group 1 improved from 0.94±23 (logMAR) to 0.73±18, whereas the mean best-corrected visual acuity improved from 0.75±16 to 0.49±0.22. The mean preoperative maximum keratometry (Kmax) was 65.23±5.03 D, whereas the mean postoperative Kmax was 53.92±4.21 D. However, in group 2, the preoperative mean UCVA was 0.63±0.31 and the postoperative UCVA was 0.55±0.29, whereas the mean best-corrected visual acuity changed from 0.31±0.26 to 0.23±0.19. The mean preoperative Kmax was 51.38±3.73 D, whereas the mean postoperative Kmax was 48.43±2.98 D. Conclusion Combined femtosecond laser-assisted Kerarings implantation and ATE-CXL is safe and effective in the treatment of PLK.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"113 1","pages":"147 - 152"},"PeriodicalIF":0.2,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49299598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating peripheral retinal vascularization and rate of recurrence after intravitreal injection of ranibizumab as a primary treatment for retinopathy of prematurity 评估玻璃体内注射雷尼单抗作为早产儿视网膜病变的主要治疗后视网膜周围血管化和复发率
IF 0.2 Q4 OPHTHALMOLOGY Pub Date : 2020-10-01 DOI: 10.4103/ejos.ejos_39_20
Mostafa El Manhaly, Ossama El Hadad, Hesham Goweini, A. Souka
Context Retinopathy of prematurity (ROP) is a vascular proliferative disease affecting premature infants. Aims The aim was to assess the extent of peripheral retinal vascular growth and recurrence rate in patients with type 1 ROP treated with ranibizumab. Settings and design Patients with ROP attending the pediatric eye clinic in the main university hospital in Alexandria Faculty of Medicine were recruited. Participants and methods This prospective study included 20 eyes of 10 patients showing type 1 ROP, treated with 0.25 mg ranibizumab intravitreal injection only. Patients were followed for 6 months, where peripheral vascularization and rate of recurrence were assessed through indirect ophthalmoscopy and RetCam imaging. Statistical analysis Data were fed to the computer and analyzed using IBM SPSS software package version 20.0. The tests used were χ2 test, Fisher’s exact test, and Student t test. Results A total of 16 (80%) eyes showed good peripheral vascularization and favorable anatomical outcome. The average timing for temporal zone III retinal vascularization was 15.71±2.09 weeks, with three eyes not reaching zone III after 6 months of injection. One eye showed retinal folding and macular ectopia. Three (15%) eyes showed signs of recurrence, with two eyes showing neovascularization at the initial vascular ridge by the fifth week after intravitreal ranibizumab injection (IVR), and one eye showing the recurrence of thick temporal ridge by the fourth months. Conclusions Ranibizumab is a potential effective treatment for patients with type 1 ROP. Delayed peripheral vascularization and disease recurrence mandate tailored long-term follow-up period according to individual response.
早产儿视网膜病变(ROP)是一种影响早产儿的血管增生性疾病。目的评估接受雷尼单抗治疗的1型ROP患者视网膜周围血管生长的程度和复发率。环境和设计招募了在亚历山大医学院主要大学医院儿童眼科诊所就诊的ROP患者。这项前瞻性研究包括10例1型ROP患者的20只眼睛,仅接受0.25 mg雷尼单抗玻璃体内注射治疗。患者随访6个月,通过间接眼镜检查和RetCam成像评估周围血管的形成和复发率。数据输入计算机,采用IBM SPSS软件包20.0版进行统计分析。采用χ2检验、Fisher确切检验和Student t检验。结果16只眼(80%)周围血管形成良好,解剖效果良好。颞区III视网膜血管化的平均时间为15.71±2.09周,有3只眼在注射6个月后未到达III区。1眼视网膜折叠,黄斑异位。3只(15%)眼睛出现复发迹象,其中2只眼睛在玻璃体内注射雷尼单抗(IVR)后第5周在初始血管嵴处出现新生血管,1只眼睛在第4个月出现厚颞嵴复发。结论雷尼单抗是治疗1型ROP的有效药物。外周血管化延迟和疾病复发需要根据个体反应量身定制长期随访期。
{"title":"Evaluating peripheral retinal vascularization and rate of recurrence after intravitreal injection of ranibizumab as a primary treatment for retinopathy of prematurity","authors":"Mostafa El Manhaly, Ossama El Hadad, Hesham Goweini, A. Souka","doi":"10.4103/ejos.ejos_39_20","DOIUrl":"https://doi.org/10.4103/ejos.ejos_39_20","url":null,"abstract":"Context Retinopathy of prematurity (ROP) is a vascular proliferative disease affecting premature infants. Aims The aim was to assess the extent of peripheral retinal vascular growth and recurrence rate in patients with type 1 ROP treated with ranibizumab. Settings and design Patients with ROP attending the pediatric eye clinic in the main university hospital in Alexandria Faculty of Medicine were recruited. Participants and methods This prospective study included 20 eyes of 10 patients showing type 1 ROP, treated with 0.25 mg ranibizumab intravitreal injection only. Patients were followed for 6 months, where peripheral vascularization and rate of recurrence were assessed through indirect ophthalmoscopy and RetCam imaging. Statistical analysis Data were fed to the computer and analyzed using IBM SPSS software package version 20.0. The tests used were χ2 test, Fisher’s exact test, and Student t test. Results A total of 16 (80%) eyes showed good peripheral vascularization and favorable anatomical outcome. The average timing for temporal zone III retinal vascularization was 15.71±2.09 weeks, with three eyes not reaching zone III after 6 months of injection. One eye showed retinal folding and macular ectopia. Three (15%) eyes showed signs of recurrence, with two eyes showing neovascularization at the initial vascular ridge by the fifth week after intravitreal ranibizumab injection (IVR), and one eye showing the recurrence of thick temporal ridge by the fourth months. Conclusions Ranibizumab is a potential effective treatment for patients with type 1 ROP. Delayed peripheral vascularization and disease recurrence mandate tailored long-term follow-up period according to individual response.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"113 1","pages":"125 - 132"},"PeriodicalIF":0.2,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41505659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of fenestration technique of the medial recuts muscle with resection of ipsilateral lateral rectus muscle in patients with sensory esotropia 感觉性内斜视患者内侧直肌开窗术与同侧直肌切除术的疗效评价
IF 0.2 Q4 OPHTHALMOLOGY Pub Date : 2020-10-01 DOI: 10.4103/ejos.ejos_28_20
M. Elkhawaga, Nehal Elshakankiri, H. Helaly, A. Elkamshoushy
Background There is an ongoing need to move toward sutureless surgery with less surgical manipulations, while maintaining the same results achieved by conventional surgery. Aim The aim was to evaluate the safety and the effectiveness of fenestration technique of the medial recuts muscle with resection of ipsilateral lateral rectus muscle in patients with sensory esotropia. Design A prospective, noncomparative, single-institution interventional study was conducted. Patients and methods This is a prospective study conducted on 16 children with sensory esotropia. Fenestration of the medial rectus muscle is a novel technique of weakening of the medial rectus by excising a rectangular wide central part extending from the insertion to a point back 5–8 mm depending on the angle of the esotropia leaving superior and inferior longitudinal muscle sleeves with no muscle sutures needed. Postoperative angle was reported at 3 months and at final follow-up. Results The procedure reduced the angle of esotropia from mean preoperative angle of 36.6±9 (20–50) to 5.3±5.9 (0–20) PD. Satisfactory horizontal alignment, defined as postoperative alignment within 8 PD of orthotropia at distance, was achieved in 81.25% of the cases at 3 months of follow-up. There were no overcorrections. The procedure was well tolerated by patients. Conclusion Fenestration technique is a safe and effective weakening procedure for medial rectus in cases of sensory esotropia.
背景目前需要在保持传统手术相同结果的同时,减少手术操作,实现无缝合手术。目的评价感觉性内斜视患者内直肌开窗术与同侧外直肌切除术的安全性和有效性。设计进行了一项前瞻性、非对照性、单一机构的介入性研究。患者和方法这是一项对16名感觉性内斜视儿童进行的前瞻性研究。内直肌开窗术是一种削弱内直肌的新技术,通过切除从插入物延伸到点后5-8的矩形宽中央部分 mm,这取决于内斜视的角度,留下不需要肌肉缝合的上下纵向肌袖。术后角度在3个月和最后随访时报告。结果该手术将内斜视的角度从术前平均36.6±9(20–50)降低到5.3±5.9(0–20)PD。在3个月的随访中,81.25%的患者获得了满意的水平对准,即术后在8 PD范围内的远距离对准。没有矫枉过正。患者对该手术耐受性良好。结论开窗术是治疗感觉性内斜视安全有效的内直肌弱化术。
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引用次数: 2
Effect of macular optical coherence tomography on decision making before silicone oil removal 黄斑光学相干断层扫描对硅油去除前决策的影响
IF 0.2 Q4 OPHTHALMOLOGY Pub Date : 2020-10-01 DOI: 10.4103/ejos.ejos_51_20
M. Elwan, Tharwat H. Mokbel, A. Badawi, W. A. Abou Samra, S. Hagras
Purpose To evaluate the role of spectral domain optical coherence tomography (SD-OCT) in affecting the decision making in eyes prepared for silicon oil removal (SOR) and to identify the cases that should have an obligatory preoperative SD-OCT. Patients and methods This prospective nonrandomized study involved patients with silicone-filled eyes recruited over the period from 2015 to 2018. Data from preoperative clinical examination and SD-OCT imaging and proposed modifications on SOR surgery based on both ways of examinations were recorded and compared. Cohen’s Kappa test was used to study the agreement between the clinical and OCT results. Results A total of 146 eyes of 138 patients were included in the study. Before SOR, clinical examination revealed normal macula in 108 (74%) eyes compared with 62 (42%) by OCT. OCT was able to detect significantly higher macular pathologies than did the clinical examination alone (P<0.0005). The number of eyes with macular edema (ME) and epiretinal membrane detected by OCT was significantly higher than that detected clinically (P<0.0005). There was a weak agreement between the results of clinical and OCT examination regarding ME (weighted K=0.426). Modifications added to the routine SOR based on clinical findings were suggested in 25 (17%) eyes compared with 65 (45%) eyes on adding OCT findings in decision making. Superadded modifications based on SD-OCT alone were significantly more in diabetic than nondiabetic patients regarding management of ME and macular retinal detachment (P=0.003). Conclusion SD-OCT was proved to be a helpful tool for following silicone-filled eyes, especially in diabetic patients. Preoperative OCT findings influenced the surgical plans of the routine SOR, thus aided in managing treatable macular lesions such as epiretinal membrane, ME, macular holes, and macular detachment.
目的评价光谱域光学相干断层扫描(SD-OCT)对硅油摘除(SOR)术前决策的影响,并确定术前必须进行SD-OCT检查的病例。这项前瞻性非随机研究纳入了2015年至2018年期间招募的硅胶填充眼患者。记录并比较术前临床检查和SD-OCT影像学资料,以及根据两种检查方法对SOR手术的修改建议。采用Cohen’s Kappa试验研究临床结果与OCT结果的一致性。结果138例患者共146只眼纳入研究。在SOR术前,临床检查显示黄斑正常的有108只(74%)眼,而OCT检查显示黄斑正常的有62只(42%)眼,OCT能发现的黄斑病变明显高于单纯的临床检查(P<0.0005)。OCT检出黄斑水肿(ME)及视网膜前膜的眼数显著高于临床检出(P<0.0005)。关于ME,临床和OCT检查的结果有微弱的一致性(加权K=0.426)。25只眼(17%)建议根据临床表现对常规SOR进行修改,而65只眼(45%)建议在决策时添加OCT表现。在ME和黄斑视网膜脱离的管理方面,糖尿病患者单独基于SD-OCT的额外修改明显多于非糖尿病患者(P=0.003)。结论SD-OCT是一种有效的硅胶眼跟踪工具,尤其适用于糖尿病患者。术前OCT检查结果影响常规SOR的手术计划,从而有助于处理可治疗的黄斑病变,如视网膜前膜、ME、黄斑孔和黄斑脱离。
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引用次数: 0
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Journal of the Egyptian Ophthalmological Society
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