Mayar M. Salaheldin, O. Nada, R. Elshinawy, Sheriff Elwan
To assess the lower lacrimal punctal measurements in patients with punctal stenosis versus normal participants using anterior segment optical coherence tomography (AS-OCT). The study included 39 puncti of 21 healthy asymptomatic volunteers attending the general and oculoplastic outpatient clinics (group I: control group) and 30 puncti of 17 patients with a clinical diagnosis of punctal stenosis defined as the punctal diameter less than 0.3 mm measured by slit-lamp biomicroscopy (group II: cases group). The punctal diameter is measured by slit-lamp biomicroscopy in all participants. The external punctal diameter, the inner punctal diameter at three depths (100, 200, and 500 μm), the punctal depth and tear meniscus height were measured using AS-OCT. The internal punctal diameter at 100 μm (239.51±91.14 vs. 168.77±118.07 µm), 200 μm (156.67±75.20 vs. 71.63±76.41 µm), and 500 μm (74.92±60.99 vs. 24.07±34.30 µm) showed statistically significant lower measurements in the cases group compared with the control group. No statistically significant differences were found comparing both groups regarding external punctal diameter otherwise. In the cases group, the punctal diameter measured by slit-lamp biomicroscopy had highly significant statistical evidence of positive correlation with the internal punctal diameter at 200 μm. AS-OCT provides a superior ability to assess the patency of the proximal lacrimal drainage system over the routine slit-lamp examination, especially when the internal punctal diameter is measured at a depth of 200 µm. Further research is required to build consensus on standard terminologies, define the standard measurements, and acquire more extensive normative databases. This would mostly be useful in diagnosis of cases of epiphora with externally nonstenosed puncti and distally patent passages.
{"title":"An anterior segment optical coherence tomography study of lower lacrimal punctal stenosis","authors":"Mayar M. Salaheldin, O. Nada, R. Elshinawy, Sheriff Elwan","doi":"10.4103/ejos.ejos_51_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_51_23","url":null,"abstract":"\u0000 \u0000 To assess the lower lacrimal punctal measurements in patients with punctal stenosis versus normal participants using anterior segment optical coherence tomography (AS-OCT).\u0000 \u0000 \u0000 \u0000 The study included 39 puncti of 21 healthy asymptomatic volunteers attending the general and oculoplastic outpatient clinics (group I: control group) and 30 puncti of 17 patients with a clinical diagnosis of punctal stenosis defined as the punctal diameter less than 0.3 mm measured by slit-lamp biomicroscopy (group II: cases group). The punctal diameter is measured by slit-lamp biomicroscopy in all participants. The external punctal diameter, the inner punctal diameter at three depths (100, 200, and 500 μm), the punctal depth and tear meniscus height were measured using AS-OCT.\u0000 \u0000 \u0000 \u0000 The internal punctal diameter at 100 μm (239.51±91.14 vs. 168.77±118.07 µm), 200 μm (156.67±75.20 vs. 71.63±76.41 µm), and 500 μm (74.92±60.99 vs. 24.07±34.30 µm) showed statistically significant lower measurements in the cases group compared with the control group. No statistically significant differences were found comparing both groups regarding external punctal diameter otherwise. In the cases group, the punctal diameter measured by slit-lamp biomicroscopy had highly significant statistical evidence of positive correlation with the internal punctal diameter at 200 μm.\u0000 \u0000 \u0000 \u0000 AS-OCT provides a superior ability to assess the patency of the proximal lacrimal drainage system over the routine slit-lamp examination, especially when the internal punctal diameter is measured at a depth of 200 µm. Further research is required to build consensus on standard terminologies, define the standard measurements, and acquire more extensive normative databases. This would mostly be useful in diagnosis of cases of epiphora with externally nonstenosed puncti and distally patent passages.\u0000","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140523122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christina S.I. Farag, Heba M.A. El-Saied, H. M. El-Mofty, R. El-Mofty
Diabetic retinopathy (DR) is a major complication of diabetes, leading to vision impairment and blindness worldwide. As early detection is crucial, our study investigated the potential of radial peripapillary capillary plexus (RPCP) and retinal nerve fiber layer (RNFL) thickness as biomarkers for retinal assessment in diabetic patients. We conducted a cross-sectional study involving 48 participants, categorized into three groups: healthy controls, diabetic patients without DR (No DR), and patients with mild to moderate nonproliferative DR (NPDR). Vascular density (VD) and RNFL thickness were evaluated using optical coherence tomography (OCT), and OCT-Angiography (OCT-A). The study showed a significant difference in VD among the three groups. The mean whole image VD% in the control group was 51.28%, while the No DR and NPDR groups had mean percentages of 49.27% and 49.46%, respectively (P=0.015). These differences were also significant for peripapillary VD (P=0.003), superior-hemi VD (P=0.035), and inferior-hemi VD percentage (P=0.002). Conversely, there were no significant differences in RNFL thickness among the groups (P=0.138). In the NPDR group, positive correlations were found between RNFL thickness and VD percentages, including superior-hemi RNFL thickness and superior-hemi VD% (r=0.724, P<0.001), average whole RNFL thickness and whole image VD% (r=0.655, P<0.001), and average whole RNFL thickness and peripapillary VD% (r=0.647, P<0.001). This research emphasizes the value of assessment of retinal VD thickness of the radial peripapillary plexus as an early indicator for preclinical diabetic retinal changes in diabetic patients.
{"title":"Assessment of the radial peripapillary capillary plexus and retinal nerve fiber layer thickness in diabetic patients in comparison to normal age-matched individuals","authors":"Christina S.I. Farag, Heba M.A. El-Saied, H. M. El-Mofty, R. El-Mofty","doi":"10.4103/ejos.ejos_72_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_72_23","url":null,"abstract":"\u0000 \u0000 Diabetic retinopathy (DR) is a major complication of diabetes, leading to vision impairment and blindness worldwide. As early detection is crucial, our study investigated the potential of radial peripapillary capillary plexus (RPCP) and retinal nerve fiber layer (RNFL) thickness as biomarkers for retinal assessment in diabetic patients.\u0000 \u0000 \u0000 \u0000 We conducted a cross-sectional study involving 48 participants, categorized into three groups: healthy controls, diabetic patients without DR (No DR), and patients with mild to moderate nonproliferative DR (NPDR). Vascular density (VD) and RNFL thickness were evaluated using optical coherence tomography (OCT), and OCT-Angiography (OCT-A).\u0000 \u0000 \u0000 \u0000 The study showed a significant difference in VD among the three groups. The mean whole image VD% in the control group was 51.28%, while the No DR and NPDR groups had mean percentages of 49.27% and 49.46%, respectively (P=0.015). These differences were also significant for peripapillary VD (P=0.003), superior-hemi VD (P=0.035), and inferior-hemi VD percentage (P=0.002). Conversely, there were no significant differences in RNFL thickness among the groups (P=0.138). In the NPDR group, positive correlations were found between RNFL thickness and VD percentages, including superior-hemi RNFL thickness and superior-hemi VD% (r=0.724, P<0.001), average whole RNFL thickness and whole image VD% (r=0.655, P<0.001), and average whole RNFL thickness and peripapillary VD% (r=0.647, P<0.001).\u0000 \u0000 \u0000 \u0000 This research emphasizes the value of assessment of retinal VD thickness of the radial peripapillary plexus as an early indicator for preclinical diabetic retinal changes in diabetic patients.\u0000","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140526995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aya A.I. Khodair, Mouhamed Elsaadany Ghoraba, R. Elseht, Dina Tadros
Loss of endothelial cells is inevitable after cataract surgery. Therefore, it is critical to protect the corneal endothelium during cataract surgery to reach good visual outcomes afterward. Maintenance of corneal clarity depends on the good function of healthy endothelial cells in addition to an intact pumping system intended to remove fluid from the corneal stoma. Our study aimed to assess changes in the corneal endothelium using specular microscopy, after intracameral injection of ceftazidime in uncomplicated phacoemulsification and compared with a placebo. The changes were measured preoperatively and 1 month postoperatively. Our prospective cohort study comprised 40 eyes from 35 patients diagnosed with cataract, all of whom underwent uncomplicated phacoemulsification for cataract extraction. Endothelial cell density significantly decreased postoperatively compared with preoperative values in both groups. Central thickness of the cornea, coefficient of variation, and visual acuity significantly increased postoperatively compared to preoperative values in both groups. Endothelial cell density showed a significant decrease postoperatively with a P value equal to 0.01 for group A (placebo group) and 0.02 for group B (ceftazidime group). Central thickness of the cornea, coefficient of variation, and visual acuity showed significant increases postoperatively with a P value equal to 0.026, 0.005, and 0.001 for group A and 0.001, 0.034, and 0.001 for group B, respectively. Ceftazidime can be considered safe for corneal endothelium when used intracamerally during phacoemulsification cataract surgery for prophylaxis of postoperative endophthalmitis.
白内障手术后，角膜内皮细胞的损失不可避免。因此，在白内障手术期间保护角膜内皮对术后达到良好的视觉效果至关重要。角膜清晰度的维持取决于健康角膜内皮细胞的良好功能，以及角膜造口液体的完整泵送系统。 我们的研究旨在使用镜检显微镜评估无并发症超声乳化术中巩膜内注射头孢唑肟后角膜内皮的变化，并与安慰剂进行比较。这些变化在术前和术后一个月进行测量。 我们的前瞻性队列研究包括 35 名白内障患者的 40 只眼睛，他们都接受了无并发症的超声乳化白内障摘除术。 与术前相比，两组患者术后内皮细胞密度均明显下降。与术前相比，两组患者术后的角膜中心厚度、变异系数和视力均明显增加。A 组（安慰剂组）和 B 组（头孢他啶组）术后内皮细胞密度明显下降，P 值分别为 0.01 和 0.02。角膜中央厚度、变异系数和视力在术后有明显增加，A 组的 P 值分别为 0.026、0.005 和 0.001，B 组的 P 值分别为 0.001、0.034 和 0.001。 在白内障超声乳化手术中，将头孢唑肟用于角膜腔内预防术后眼内炎对角膜内皮是安全的。
{"title":"Effect of intracameral injection of ceftazidime on corneal endothelium by specular microscope after uncomplicated phacoemulsification cataract surgery","authors":"Aya A.I. Khodair, Mouhamed Elsaadany Ghoraba, R. Elseht, Dina Tadros","doi":"10.4103/ejos.ejos_85_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_85_23","url":null,"abstract":"\u0000 \u0000 Loss of endothelial cells is inevitable after cataract surgery. Therefore, it is critical to protect the corneal endothelium during cataract surgery to reach good visual outcomes afterward. Maintenance of corneal clarity depends on the good function of healthy endothelial cells in addition to an intact pumping system intended to remove fluid from the corneal stoma.\u0000 \u0000 \u0000 \u0000 Our study aimed to assess changes in the corneal endothelium using specular microscopy, after intracameral injection of ceftazidime in uncomplicated phacoemulsification and compared with a placebo. The changes were measured preoperatively and 1 month postoperatively.\u0000 \u0000 \u0000 \u0000 Our prospective cohort study comprised 40 eyes from 35 patients diagnosed with cataract, all of whom underwent uncomplicated phacoemulsification for cataract extraction.\u0000 \u0000 \u0000 \u0000 Endothelial cell density significantly decreased postoperatively compared with preoperative values in both groups. Central thickness of the cornea, coefficient of variation, and visual acuity significantly increased postoperatively compared to preoperative values in both groups. Endothelial cell density showed a significant decrease postoperatively with a P value equal to 0.01 for group A (placebo group) and 0.02 for group B (ceftazidime group). Central thickness of the cornea, coefficient of variation, and visual acuity showed significant increases postoperatively with a P value equal to 0.026, 0.005, and 0.001 for group A and 0.001, 0.034, and 0.001 for group B, respectively.\u0000 \u0000 \u0000 \u0000 Ceftazidime can be considered safe for corneal endothelium when used intracamerally during phacoemulsification cataract surgery for prophylaxis of postoperative endophthalmitis.\u0000","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140518590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The goal of this study is to assess the effectiveness of implantation of an Ahmed glaucoma valve (AGV) augmented with the use of mitomycin-C (MMC) and preserved amniotic membrane (AM), as a first line of intervention in cases of advanced primary congenital glaucoma (PCG). Prospective clinical and interventional trial was done on 30 eyes of 24 patients, aged between 6 months and 3 years, with advanced PCG at presentation. AGV (model FP8) implantation augmented with use of MMC and two layers of cryopreserved human AM as a primary intervention. At all-time intervals (at day 1, 1, 3, and 12 months following surgery), the postoperative intraocular pressures (IOPs) were significantly lower than the preoperative IOPs (16.83±2.78 mmHg at month 12 compared with a preoperative IOP of 38.29±4.23 mmHg). At all times, the postoperative corneal diameter was not noticeably smaller than the preoperative values (13.79±0.57 mm at month 12 compared with preoperative value of 13.93±0.58 mm). AGV augmented with the use of MMC and AM can be considered as a secure and reliable approach for management of cases of advanced PCG, without additional risks compared with other techniques.
{"title":"Ahmed glaucoma valve augmented with mitomycin C and amniotic membrane as a first intervention in advanced primary congenital glaucoma","authors":"Haytham M. Ali, Fareed Wagdy, A. Tharwat","doi":"10.4103/ejos.ejos_71_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_71_23","url":null,"abstract":"\u0000 \u0000 The goal of this study is to assess the effectiveness of implantation of an Ahmed glaucoma valve (AGV) augmented with the use of mitomycin-C (MMC) and preserved amniotic membrane (AM), as a first line of intervention in cases of advanced primary congenital glaucoma (PCG).\u0000 \u0000 \u0000 \u0000 Prospective clinical and interventional trial was done on 30 eyes of 24 patients, aged between 6 months and 3 years, with advanced PCG at presentation. AGV (model FP8) implantation augmented with use of MMC and two layers of cryopreserved human AM as a primary intervention.\u0000 \u0000 \u0000 \u0000 At all-time intervals (at day 1, 1, 3, and 12 months following surgery), the postoperative intraocular pressures (IOPs) were significantly lower than the preoperative IOPs (16.83±2.78 mmHg at month 12 compared with a preoperative IOP of 38.29±4.23 mmHg). At all times, the postoperative corneal diameter was not noticeably smaller than the preoperative values (13.79±0.57 mm at month 12 compared with preoperative value of 13.93±0.58 mm).\u0000 \u0000 \u0000 \u0000 AGV augmented with the use of MMC and AM can be considered as a secure and reliable approach for management of cases of advanced PCG, without additional risks compared with other techniques.\u0000","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140523539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Esraa El Ghoubashy, Mohamed N. Gad, F. Wagdy, Marwa A. Zaki
To assess the causes and management of low vision in school-age children in Menoufia Governorate. This prospective study was made among 140 children with vision impairment aged from 6 to 18 years who came to the low-vision clinic of the Department of Ophthalmology of Menoufia University Hospitals with visual acuity less than 6/18 in the better eye best correction. A complete history was obtained. Complete examination of the anterior and posterior segments was done. Strabismus existence was determined. Refractive errors were measured. Before and after using low-vision aids, near and far visual acuity was measured. The mean age of patients was 11.94±3.61 years; 76 (54.29%) of the children were males and 64 (45.71%) of the children were females. According to the distribution of the diagnoses, hereditary fundus dystrophies were the most prevalent diagnosis among the children, accounting for 28.57% of diagnoses, followed by albinism (20%). The rehabilitation techniques that were mostly used were telescopic glasses (54.29%) for distant vision, electronic magnifiers (31.43%), and optical magnifiers (20.0%) for near vision. Low-vision devices were shown to significantly improve both near and distant visual acuity. Visual rehabilitation for school-age children with visual impairment can result in a considerable improvement in both distant and near vision. As a result, pediatricians and ophthalmologists must recommend vision rehabilitation for children with vision impairment.
{"title":"Low vision in school-age children in Menoufia Governorate","authors":"Esraa El Ghoubashy, Mohamed N. Gad, F. Wagdy, Marwa A. Zaki","doi":"10.4103/ejos.ejos_56_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_56_23","url":null,"abstract":"\u0000 \u0000 To assess the causes and management of low vision in school-age children in Menoufia Governorate.\u0000 \u0000 \u0000 \u0000 This prospective study was made among 140 children with vision impairment aged from 6 to 18 years who came to the low-vision clinic of the Department of Ophthalmology of Menoufia University Hospitals with visual acuity less than 6/18 in the better eye best correction. A complete history was obtained. Complete examination of the anterior and posterior segments was done. Strabismus existence was determined. Refractive errors were measured. Before and after using low-vision aids, near and far visual acuity was measured.\u0000 \u0000 \u0000 \u0000 The mean age of patients was 11.94±3.61 years; 76 (54.29%) of the children were males and 64 (45.71%) of the children were females. According to the distribution of the diagnoses, hereditary fundus dystrophies were the most prevalent diagnosis among the children, accounting for 28.57% of diagnoses, followed by albinism (20%). The rehabilitation techniques that were mostly used were telescopic glasses (54.29%) for distant vision, electronic magnifiers (31.43%), and optical magnifiers (20.0%) for near vision. Low-vision devices were shown to significantly improve both near and distant visual acuity.\u0000 \u0000 \u0000 \u0000 Visual rehabilitation for school-age children with visual impairment can result in a considerable improvement in both distant and near vision. As a result, pediatricians and ophthalmologists must recommend vision rehabilitation for children with vision impairment.\u0000","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140525228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Menna A.M. Abdel Twaab, Heba A El Gendy, Mohamed M. El-Sayed, Shaimaa Arfeen
To evaluate corneal and epithelial thickness using the anterior segment optical coherence tomography and to correlate these changes with major disease parameters, that is duration of the disease, status of control (glycated hemoglobin level), and stage of diabetic retinopathy. Corneal and epithelial thickness profile of 25 patients diagnosed with diabetes mellitus and 25 healthy individuals were measured by anterior segment optical coherence tomography. Full ophthalmological examination of all patients was done. The disease duration and the glycated hemoglobin levels were recorded. In diabetic patients, there was nonsignificant thinning in mean central epithelial thickness (P=0.14). The mean central corneal thickness is slightly thicker, however, it did not reach significance (P=0.051). There was statistically significant thickening in central stromal thickness (P=0.015). There was a significant negative correlation between the severity of retinopathy and superior epithelial thickness (P=0.037). The duration of the disease showed significant correlation with most of epithelial thickness values, however, HA1c level was not found to have any statistically significant effect on corneal and epithelial parameters. Chronic metabolic stress of diabetes has an impact on corneal epithelium and stroma. Severity of diabetic retinopathy should be considered as a risk factor during corneal surgeries to avoid epithelial and stromal-associated complications.
{"title":"Corneal and epithelial thickness mapping in diabetic patients using optical coherence tomography","authors":"Menna A.M. Abdel Twaab, Heba A El Gendy, Mohamed M. El-Sayed, Shaimaa Arfeen","doi":"10.4103/ejos.ejos_76_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_76_23","url":null,"abstract":"\u0000 \u0000 To evaluate corneal and epithelial thickness using the anterior segment optical coherence tomography and to correlate these changes with major disease parameters, that is duration of the disease, status of control (glycated hemoglobin level), and stage of diabetic retinopathy.\u0000 \u0000 \u0000 \u0000 Corneal and epithelial thickness profile of 25 patients diagnosed with diabetes mellitus and 25 healthy individuals were measured by anterior segment optical coherence tomography. Full ophthalmological examination of all patients was done. The disease duration and the glycated hemoglobin levels were recorded.\u0000 \u0000 \u0000 \u0000 In diabetic patients, there was nonsignificant thinning in mean central epithelial thickness (P=0.14). The mean central corneal thickness is slightly thicker, however, it did not reach significance (P=0.051). There was statistically significant thickening in central stromal thickness (P=0.015). There was a significant negative correlation between the severity of retinopathy and superior epithelial thickness (P=0.037). The duration of the disease showed significant correlation with most of epithelial thickness values, however, HA1c level was not found to have any statistically significant effect on corneal and epithelial parameters.\u0000 \u0000 \u0000 \u0000 Chronic metabolic stress of diabetes has an impact on corneal epithelium and stroma. Severity of diabetic retinopathy should be considered as a risk factor during corneal surgeries to avoid epithelial and stromal-associated complications.\u0000","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140515734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Varsha V. Manade, Megha R. Kotecha, Surbhi A. Chodvadiya, Jhimli Ta, Radhika R. Paranjpe
To compare and correlate the intraocular pressure (IOP) measurement obtained by Goldmann applanation tonometer (GAT), noncontact tonometer (NCT), and tonopen in normal and glaucomatous patients. A cross-sectional, observational, and comparative study was carried out. Two hundred eyes of 100 patients were screened, detailed history was taken, and thorough ocular examination was done. IOP was recorded using NCT (Keeler Pulsair), Tonopen (Tonopen XL), and GAT. Gonioscopy, optic disc examination, central corneal thickness, and visual field testing were done. The mean age of the study group was 53.25 years. Mean IOP by NCT was 19.20 mmHg, by GAT was 22.44 mmHg, and by tonopen was 19.33 mmHg. There was statistically significant difference between mean IOP with respect to method used (P<0.001). Forty-eight percent of eyes, 40% eyes, and 49% eyes had IOP less than 18 mmHg by NCT, GAT, and tonopen, respectively. In total, 35.5% eyes, 19.5% eyes, and 35.5% eyes had IOP ranging between 18 and 25 mmHg by NCT, GAT, and tonopen, respectively. In total, 16.5% eyes, 40.5% eyes, and 15.5% eyes had IOP more than 25 mmHg by NCT, GAT, and tonopen, respectively. NCT and tonopen readings correlate well with GAT readings in physiologic IOP range up to 20 mmHg, but at higher IOP range they tend to underestimate IOP readings as compared with GAT. However, NCT and tonopen can be used for screening purpose as they are portable and easy to use.
{"title":"Comparative study of recording intraocular pressure in adults by three different tonometers Goldmann applanation tonometer, noncontact tonometer, and tonopen","authors":"Varsha V. Manade, Megha R. Kotecha, Surbhi A. Chodvadiya, Jhimli Ta, Radhika R. Paranjpe","doi":"10.4103/ejos.ejos_50_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_50_23","url":null,"abstract":"\u0000 \u0000 To compare and correlate the intraocular pressure (IOP) measurement obtained by Goldmann applanation tonometer (GAT), noncontact tonometer (NCT), and tonopen in normal and glaucomatous patients.\u0000 \u0000 \u0000 \u0000 A cross-sectional, observational, and comparative study was carried out. Two hundred eyes of 100 patients were screened, detailed history was taken, and thorough ocular examination was done. IOP was recorded using NCT (Keeler Pulsair), Tonopen (Tonopen XL), and GAT. Gonioscopy, optic disc examination, central corneal thickness, and visual field testing were done.\u0000 \u0000 \u0000 \u0000 The mean age of the study group was 53.25 years. Mean IOP by NCT was 19.20 mmHg, by GAT was 22.44 mmHg, and by tonopen was 19.33 mmHg. There was statistically significant difference between mean IOP with respect to method used (P<0.001). Forty-eight percent of eyes, 40% eyes, and 49% eyes had IOP less than 18 mmHg by NCT, GAT, and tonopen, respectively. In total, 35.5% eyes, 19.5% eyes, and 35.5% eyes had IOP ranging between 18 and 25 mmHg by NCT, GAT, and tonopen, respectively. In total, 16.5% eyes, 40.5% eyes, and 15.5% eyes had IOP more than 25 mmHg by NCT, GAT, and tonopen, respectively.\u0000 \u0000 \u0000 \u0000 NCT and tonopen readings correlate well with GAT readings in physiologic IOP range up to 20 mmHg, but at higher IOP range they tend to underestimate IOP readings as compared with GAT. However, NCT and tonopen can be used for screening purpose as they are portable and easy to use.\u0000","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140516769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yasmine A. Deiaeldin, Mona Mohammad Elsharkawy, Hadeel M. Abdelrahman, Khadija Alforjani Abdulhadi Omar, Mohammed A Al-Naimy
Nephrotic syndrome (NS) is by far, the most common glomerular disease in childhood period and is considered as one of the main aetiologies of child exposure to systemic steroids. High-dose corticosteroids for NS, are usually prescribed by pediatrians for a long period. Posterior subcapsular cataract (PSC) and increased intraocular pressure (IOP) are the two most common ocular complications associated with steroid treatment. The exact incidence, prevalence, severity, and time of cataract and glaucoma onset in those childrens have not yet been thoroughly investigated. Evaluating the incidence of cataract and glaucoma in children with NS receiving steroid treatment during and after treatment cessation. This cohort prospective study was done at the Pediatric Nephrology Clinic at Zagazig University Children’s Hospital in co-operation with the Department of Ophthalmology, Zagazig University, for detailed eye examination. Totally 48 children with primary NS who received corticosteroids either as a single treatment or with other treatment modalities for more than 3 months were included in our study. Clinical features plus laboratory tests confirmed by renal biopsy were the main parameters used in the diagnosis of NS. Posterior subcapsular cataracts (PSC) were observed in 14 patients (29.2%). All studied patients had normal intraocular pressure ranging between 10 and 20 mmHg in both eyes during the follow-up period with no glaucomatous optic disc changes observed. A significant number of children with NS treated with steroids are liable to develop cataracts and glaucoma that may progress and need surgery to preserve vision, so they have to be well diagnosed and followed-up.
{"title":"Incidence of cataract and glaucoma in children with nephrotic syndrome undergoing steroid treatment","authors":"Yasmine A. Deiaeldin, Mona Mohammad Elsharkawy, Hadeel M. Abdelrahman, Khadija Alforjani Abdulhadi Omar, Mohammed A Al-Naimy","doi":"10.4103/ejos.ejos_68_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_68_23","url":null,"abstract":"Nephrotic syndrome (NS) is by far, the most common glomerular disease in childhood period and is considered as one of the main aetiologies of child exposure to systemic steroids. High-dose corticosteroids for NS, are usually prescribed by pediatrians for a long period. Posterior subcapsular cataract (PSC) and increased intraocular pressure (IOP) are the two most common ocular complications associated with steroid treatment. The exact incidence, prevalence, severity, and time of cataract and glaucoma onset in those childrens have not yet been thoroughly investigated. Evaluating the incidence of cataract and glaucoma in children with NS receiving steroid treatment during and after treatment cessation. This cohort prospective study was done at the Pediatric Nephrology Clinic at Zagazig University Children’s Hospital in co-operation with the Department of Ophthalmology, Zagazig University, for detailed eye examination. Totally 48 children with primary NS who received corticosteroids either as a single treatment or with other treatment modalities for more than 3 months were included in our study. Clinical features plus laboratory tests confirmed by renal biopsy were the main parameters used in the diagnosis of NS. Posterior subcapsular cataracts (PSC) were observed in 14 patients (29.2%). All studied patients had normal intraocular pressure ranging between 10 and 20 mmHg in both eyes during the follow-up period with no glaucomatous optic disc changes observed. A significant number of children with NS treated with steroids are liable to develop cataracts and glaucoma that may progress and need surgery to preserve vision, so they have to be well diagnosed and followed-up.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139328303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Megha Kotecha, Aman Khanna, Varsha Manade, Jhimli Ta, Surbhi A. Chodvadiya
To evaluate the functional visual recovery following phacoemulsification cataract surgery with foldable intraocular lens implantation through a temporal clear corneal incision. This prospective study was conducted at a tertiary health care centre in Western Maharashtra over a period of 2 years. Detailed history was taken and thorough ocular examination of was done. Visual Acuity, Color vision, Contrast sensitivity, Binocular vision was noted. Visual Fields were examined and Glare Disability was assessed. All patients underwent temporal clear corneal Phacoemulsification surgery through a 3.2 mm incision with implantation of an Aspheric Monofocal Foldable IOL under LA. All patients were started on tapering dose of antibiotic − steroid over 6 weeks and followed up post operatively on day 1, week 1, week 2, 6 weeks, 3months and at 6 months. 50 eyes of 46 patients with immature cataract aged between 40 to 80 years were included. At the end of 24 weeks the Distance Vision was ≥ 6/9 in 31 eyes, 6/18–6/12 in 17 eyes and < 6/18 in 2 eyes. It was a statistically significant difference (P<0.0001). No significant difference in near vision was seen at the end of 6 months. The difference in astigmatism post operatively in all 50 eyes was not statistically significant at the end of 6 months (P<0.05). Significant improvement in contrast sensitivity was seen post operatively (P<0.0001). The mean glare disability was 14.06 s at 24 weeks. No significant difference was seen (P>0.05). Colour vision and Field of vision were similar postoperatively. All the patients maintained grade 3 binocular vision at end of the study. Phacoemulsification with monofocal foldable intraocular lenses can be the choice of technique in treatment of cataract as being able to provide excellent visual results and also being cost effective.
{"title":"Clinical study of functional visual recovery following phacoemulsification with IOL implantation","authors":"Megha Kotecha, Aman Khanna, Varsha Manade, Jhimli Ta, Surbhi A. Chodvadiya","doi":"10.4103/ejos.ejos_60_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_60_23","url":null,"abstract":"To evaluate the functional visual recovery following phacoemulsification cataract surgery with foldable intraocular lens implantation through a temporal clear corneal incision. This prospective study was conducted at a tertiary health care centre in Western Maharashtra over a period of 2 years. Detailed history was taken and thorough ocular examination of was done. Visual Acuity, Color vision, Contrast sensitivity, Binocular vision was noted. Visual Fields were examined and Glare Disability was assessed. All patients underwent temporal clear corneal Phacoemulsification surgery through a 3.2 mm incision with implantation of an Aspheric Monofocal Foldable IOL under LA. All patients were started on tapering dose of antibiotic − steroid over 6 weeks and followed up post operatively on day 1, week 1, week 2, 6 weeks, 3months and at 6 months. 50 eyes of 46 patients with immature cataract aged between 40 to 80 years were included. At the end of 24 weeks the Distance Vision was ≥ 6/9 in 31 eyes, 6/18–6/12 in 17 eyes and < 6/18 in 2 eyes. It was a statistically significant difference (P<0.0001). No significant difference in near vision was seen at the end of 6 months. The difference in astigmatism post operatively in all 50 eyes was not statistically significant at the end of 6 months (P<0.05). Significant improvement in contrast sensitivity was seen post operatively (P<0.0001). The mean glare disability was 14.06 s at 24 weeks. No significant difference was seen (P>0.05). Colour vision and Field of vision were similar postoperatively. All the patients maintained grade 3 binocular vision at end of the study. Phacoemulsification with monofocal foldable intraocular lenses can be the choice of technique in treatment of cataract as being able to provide excellent visual results and also being cost effective.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139328383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nada M.Y. El Adawy, Yasser S. Mohamed, Noha M. Khalil, Yasmine M. Elsayed, Mohamed B. Kenawy
The aim of this study was to compare 2% dorzolamide/0.5% timolol fixed combination brand name drug (Cosopt) to its generic counterpart (Twinzol) regarding efficacy and side effects. The study included 92 eyes of 92 patients diagnosed with primary open-angle glaucoma and are indicated for antiglaucoma fixed combination of 20 mg/ml dorzolamide/5 mg/ml timolol). Patients were randomly divided into two groups: the first group received Cosopt, whereas the second received Twinzol. In visit, intraocular pressure (IOP) was measured and any local side effects by either eye drops was recorded. Monitoring and recording the percentage of IOP drop each month and all over the 3 months duration of follow up visits were done. The percentage of IOP drop for Cosopt and Twinzol after 1 month showed a significant P value of 0.032, with a mean percent reduction in IOP of 28.55%, median percent reduction of 26.92%, the minimum is 3.82% while the maximum is 62.96% for the Cosopt group, while that for Twinzol was 23.14, 21.29, 4.17, and 57.14%, respectively. On the other hand, the percentage of drop of IOP between the two groups after 3 months showed insignificant P value (0.646). IOP measurement was statistically insignificant between the two groups at 1 (0.462) and 3 months (0.639). As regards side effects; both eye drops were comparable with an insignificant P value of 0.49. The study demonstrated a reliable efficacy and safety on using generic therapy Twinzol compared with band counterpart Cosopt.
{"title":"A comparison between 2% dorzolamide/0.5% timolol fixed combination: brand name drug to its generic counterpart regarding efficacy and side effects","authors":"Nada M.Y. El Adawy, Yasser S. Mohamed, Noha M. Khalil, Yasmine M. Elsayed, Mohamed B. Kenawy","doi":"10.4103/ejos.ejos_33_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_33_23","url":null,"abstract":"The aim of this study was to compare 2% dorzolamide/0.5% timolol fixed combination brand name drug (Cosopt) to its generic counterpart (Twinzol) regarding efficacy and side effects. The study included 92 eyes of 92 patients diagnosed with primary open-angle glaucoma and are indicated for antiglaucoma fixed combination of 20 mg/ml dorzolamide/5 mg/ml timolol). Patients were randomly divided into two groups: the first group received Cosopt, whereas the second received Twinzol. In visit, intraocular pressure (IOP) was measured and any local side effects by either eye drops was recorded. Monitoring and recording the percentage of IOP drop each month and all over the 3 months duration of follow up visits were done. The percentage of IOP drop for Cosopt and Twinzol after 1 month showed a significant P value of 0.032, with a mean percent reduction in IOP of 28.55%, median percent reduction of 26.92%, the minimum is 3.82% while the maximum is 62.96% for the Cosopt group, while that for Twinzol was 23.14, 21.29, 4.17, and 57.14%, respectively. On the other hand, the percentage of drop of IOP between the two groups after 3 months showed insignificant P value (0.646). IOP measurement was statistically insignificant between the two groups at 1 (0.462) and 3 months (0.639). As regards side effects; both eye drops were comparable with an insignificant P value of 0.49. The study demonstrated a reliable efficacy and safety on using generic therapy Twinzol compared with band counterpart Cosopt.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139327569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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