Pub Date : 2023-08-13DOI: 10.24198/pjd.vol35no2.47031
Florenly Florenly, Shieny Lokanata, Jovin Friando, Phuong Thao Mai, H. Le, Cut Cynthia Luzria, Anusak Sintapanont
ABSTRACTIntroduction: Red beetroots (Beta vulgaris L.) are a natural ingredient rich in nutrients and provide various notable health benefits. In dentistry, red beetroots have the potential to act as a plaque-disclosing agent. Previous studies showed that red beetroot preparation in gelform is more effective compared to chewable tablets, but has significant drawbacks in taste. Effervescent granules have the potential to conceal the unpleasant taste of beetroot substances. This study aims to determine the ideal formula and evaluate the physical properties and stability of effervescent granules made from red beetroot extract. Methods: This was an experimental design study with descriptive analysis. The maceration method was used to extract the red beetroot constituents. Fresh fruits were collected, air-dried, and macerated with 96% ethanol twice. The filtrates were then concentrated. The wet granulation method was used to formulate effervescent granules. The samples were grouped into formula 1 (F1), formula 2 (F2), and formula 3 (F3) using 1%, 3%, and 4% red beetroot extract, respectively. All sample groups were analyzed for physical stability, namely: organoleptic, flowability, density, dissolving time, and pH tests. Results: All samples surpassed the sensory evaluation for physical properties. Formula 1 (1%) and formula 2 (3%) models passed all the physical stability tests. Meanwhile, the 4% formula (F3) failed two physical tests. F1 (1%) samples also showed lighter brown color for its lower beetroot extract concentration, indicating under-qualification as dental plaque staining materials. Therefore, 3% concentration (F2) has the best formulation regarding physical properties and stability. Conclusion: Formulas F1 and F2 have the best physical properties and stability by passing all the tests, while Formula 3 failed the organoleptic and flow rate tests.KEYWORDSformulation, physical stability, Beta vulgaris L, effervescent granules
{"title":"Formulation and physical stability analysis of red beetroots (Beta vulgaris l.) effervescent granules","authors":"Florenly Florenly, Shieny Lokanata, Jovin Friando, Phuong Thao Mai, H. Le, Cut Cynthia Luzria, Anusak Sintapanont","doi":"10.24198/pjd.vol35no2.47031","DOIUrl":"https://doi.org/10.24198/pjd.vol35no2.47031","url":null,"abstract":"ABSTRACTIntroduction: Red beetroots (Beta vulgaris L.) are a natural ingredient rich in nutrients and provide various notable health benefits. In dentistry, red beetroots have the potential to act as a plaque-disclosing agent. Previous studies showed that red beetroot preparation in gelform is more effective compared to chewable tablets, but has significant drawbacks in taste. Effervescent granules have the potential to conceal the unpleasant taste of beetroot substances. This study aims to determine the ideal formula and evaluate the physical properties and stability of effervescent granules made from red beetroot extract. Methods: This was an experimental design study with descriptive analysis. The maceration method was used to extract the red beetroot constituents. Fresh fruits were collected, air-dried, and macerated with 96% ethanol twice. The filtrates were then concentrated. The wet granulation method was used to formulate effervescent granules. The samples were grouped into formula 1 (F1), formula 2 (F2), and formula 3 (F3) using 1%, 3%, and 4% red beetroot extract, respectively. All sample groups were analyzed for physical stability, namely: organoleptic, flowability, density, dissolving time, and pH tests. Results: All samples surpassed the sensory evaluation for physical properties. Formula 1 (1%) and formula 2 (3%) models passed all the physical stability tests. Meanwhile, the 4% formula (F3) failed two physical tests. F1 (1%) samples also showed lighter brown color for its lower beetroot extract concentration, indicating under-qualification as dental plaque staining materials. Therefore, 3% concentration (F2) has the best formulation regarding physical properties and stability. Conclusion: Formulas F1 and F2 have the best physical properties and stability by passing all the tests, while Formula 3 failed the organoleptic and flow rate tests.KEYWORDSformulation, physical stability, Beta vulgaris L, effervescent granules","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44819485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-13DOI: 10.24198/pjd.vol35no2.46171
Rizka Maya Silvia, Chrysmyta Fiola Viandisa, A. M. Prihanti, M. A. Wahyukundari, Y. M. D. Arina
ABSTRACTIntroduction: Staphylococcus aureus (S. aureus) and Porphyromonas gingivalis (P. gingivalis) are the two main bacteria that cause dental and oral disease. Cacao leaves have been reported to have antibacterial properties. However, the active compounds in cacao leaves vary depending on the age of the leaves and the place where these plants grow. This research aims to analyze the active ingredients and antibacterial effectiveness of the Edel varieties cacao leaves against S. aureus and P. gingivalis. Methods: This is an experimental study. The Cacao leaves from PTPN 12 Plantation Banjarsari Jember were extracted by the maceration technique in concentrations of 25, 50, 75%, and 100%. The phytochemical test was then made using the Thin Layer Chromatography (TLC). The antibacterial activity of Cacao leaf extract against S. aureus ATCC 25923 and P. gingivalis ATCC 33277 was examined using the Disc Diffusion technique on Mueller Hinton Agar (MHA) media. Results: The Cacao leaf extract of the Edel varieties from Jember contained flavonoids, saponins, and tannins but did not contain alkaloids. In all concentrations tested, the Cacao leaf extract of the Edel varieties from Jember showed the inhibition zones of S. aureus and P. gingivalis. The concentration of 100% showed the greatest antibacterial activity (The highest antibacterial activity was observed at a concentration of 100%), which was moderate against S. aureus (10.98 mm ± 0,93) and strong against P. gingivalis (11.54 mm ± 0,41). There was a significant difference among concentrations in both the P.gingivalis and S.aureus bacterial groups (p<0.001). At the same concentration, there was no significant difference between P. gingivalis and S. aureus (p>0.001). Conclusion: Cacao leaf extract of the Edel varieties contains flavonoids, saponins and tannins and has antibacterial activity against S. aureus and P. gingivalis.KEYWORDScacao leaves extract, Edel varieties, antibacterial, S. aureus, P. gingivalis
{"title":"The effectiveness of Edel varieties cacao leaves extract as antibacterial against Staphylococcus aureus and Porphyromonas gingivalis : an experimental study","authors":"Rizka Maya Silvia, Chrysmyta Fiola Viandisa, A. M. Prihanti, M. A. Wahyukundari, Y. M. D. Arina","doi":"10.24198/pjd.vol35no2.46171","DOIUrl":"https://doi.org/10.24198/pjd.vol35no2.46171","url":null,"abstract":"ABSTRACTIntroduction: Staphylococcus aureus (S. aureus) and Porphyromonas gingivalis (P. gingivalis) are the two main bacteria that cause dental and oral disease. Cacao leaves have been reported to have antibacterial properties. However, the active compounds in cacao leaves vary depending on the age of the leaves and the place where these plants grow. This research aims to analyze the active ingredients and antibacterial effectiveness of the Edel varieties cacao leaves against S. aureus and P. gingivalis. Methods: This is an experimental study. The Cacao leaves from PTPN 12 Plantation Banjarsari Jember were extracted by the maceration technique in concentrations of 25, 50, 75%, and 100%. The phytochemical test was then made using the Thin Layer Chromatography (TLC). The antibacterial activity of Cacao leaf extract against S. aureus ATCC 25923 and P. gingivalis ATCC 33277 was examined using the Disc Diffusion technique on Mueller Hinton Agar (MHA) media. Results: The Cacao leaf extract of the Edel varieties from Jember contained flavonoids, saponins, and tannins but did not contain alkaloids. In all concentrations tested, the Cacao leaf extract of the Edel varieties from Jember showed the inhibition zones of S. aureus and P. gingivalis. The concentration of 100% showed the greatest antibacterial activity (The highest antibacterial activity was observed at a concentration of 100%), which was moderate against S. aureus (10.98 mm ± 0,93) and strong against P. gingivalis (11.54 mm ± 0,41). There was a significant difference among concentrations in both the P.gingivalis and S.aureus bacterial groups (p<0.001). At the same concentration, there was no significant difference between P. gingivalis and S. aureus (p>0.001). Conclusion: Cacao leaf extract of the Edel varieties contains flavonoids, saponins and tannins and has antibacterial activity against S. aureus and P. gingivalis.KEYWORDScacao leaves extract, Edel varieties, antibacterial, S. aureus, P. gingivalis ","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41688384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-13DOI: 10.24198/pjd.vol35no2.47073
Deli Mona, Izzati Hamidah, Puji Kurnia, Khatijah Lim Abdullah
ABSTRACTIntroduction: The surface hardness of enamel is affected by demineralization and remineralization of enamel. Demineralization can cause the enamel surface hardness to decrease. Carbonated drinks are acidic drinks which can lower the pH of the oral cavity and cause damage to the enamel. Lost tooth minerals can be restored with remineralizing materials, one of which contains calcium. Natural materials that can help remineralization are calcium carbonate (CaCO3) which can be found in several animal shells such as marine materials, pearl snails and eggshells. Duck eggshell is one of the household wastes which is high in calcium which consists of 94% calcium carbonate. The purpose of this study is to analyze differences in enamel surface hardness between soaking carbonated drinks and application of duck eggshell paste remineralization material. Methods: This type of research is a true experimental laboratory with a pretest-posttest research design with control group design. The study sample was 8 post-extraction premolars that matched the inclusion criteria. The samples were divided into two groups which were previously soaked in carbonated drinks for 15 minutes. Group I: duck eggshell paste and group II: pasta without duck eggshell which was applied for 3 minutes 2 times a day for 14 days. Hardness measurement using Vickers hardness tester. Results: based on data analysis using paired t-test. Enamel surface hardness after immersion in carbonated drinks (mean=327.50 SD=23.33). The enamel surface hardness increased after application of duck eggshell paste (mean=467.50, SD=14.15) p=0.001. The control group also increased after the application of pasta without duck eggshell (mean=429.40 SD=29.01) p=0.002. Conclusion: There is a difference in the hardness of the enamel surface after being soaked in carbonated drinks and after the application of duck egg shell paste. KEYWORDSdemineralization, enamel surface hardness, carbonated drinks, duck egg shell paste, remineralization.
{"title":"Differences in enamel surface hardness between soaking carbonated drinks and application of duck eggshell paste remineralization material","authors":"Deli Mona, Izzati Hamidah, Puji Kurnia, Khatijah Lim Abdullah","doi":"10.24198/pjd.vol35no2.47073","DOIUrl":"https://doi.org/10.24198/pjd.vol35no2.47073","url":null,"abstract":"ABSTRACTIntroduction: The surface hardness of enamel is affected by demineralization and remineralization of enamel. Demineralization can cause the enamel surface hardness to decrease. Carbonated drinks are acidic drinks which can lower the pH of the oral cavity and cause damage to the enamel. Lost tooth minerals can be restored with remineralizing materials, one of which contains calcium. Natural materials that can help remineralization are calcium carbonate (CaCO3) which can be found in several animal shells such as marine materials, pearl snails and eggshells. Duck eggshell is one of the household wastes which is high in calcium which consists of 94% calcium carbonate. The purpose of this study is to analyze differences in enamel surface hardness between soaking carbonated drinks and application of duck eggshell paste remineralization material. Methods: This type of research is a true experimental laboratory with a pretest-posttest research design with control group design. The study sample was 8 post-extraction premolars that matched the inclusion criteria. The samples were divided into two groups which were previously soaked in carbonated drinks for 15 minutes. Group I: duck eggshell paste and group II: pasta without duck eggshell which was applied for 3 minutes 2 times a day for 14 days. Hardness measurement using Vickers hardness tester. Results: based on data analysis using paired t-test. Enamel surface hardness after immersion in carbonated drinks (mean=327.50 SD=23.33). The enamel surface hardness increased after application of duck eggshell paste (mean=467.50, SD=14.15) p=0.001. The control group also increased after the application of pasta without duck eggshell (mean=429.40 SD=29.01) p=0.002. Conclusion: There is a difference in the hardness of the enamel surface after being soaked in carbonated drinks and after the application of duck egg shell paste. KEYWORDSdemineralization, enamel surface hardness, carbonated drinks, duck egg shell paste, remineralization.","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44047628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACTIntroduction: Celery (Apium graveolens L.) is a member of the Apiaceae family that can grow everywhere. Celery contains flavonoids, saponins, tannins, essential oils, apigenin, choline, vitamins A, B, C, asparagine bitter substances. Celery contains flavonoids, saponins, and tannins which are antibacterial compounds. Streptococcus mutans is a Gram-positive bacterium creating an acidic atmosphere in the oral cavity, which causes insufficient saliva to prevent enamel demineralisation which can lead to dental caries. The purpose of this study was to analyze the inhibition effect of celery leaf extract (Apium graveolens L.) on the growth of Streptococcus mutans. Methods: This type of experimental laboratory research uses the Post Test Only Control Group Design. The samples were Apium graveolens L. and Streptococcus mutans ATCC 25175. The number of treatment groups was 24 with concentrations of 20, 40, 60, and 80%. Toothpaste containing antibacterial ingredients was used as positive control and for negative control, a basic toothpaste formula without antibacterial ingredients, namely carboxymethyl cellulose (CMC), xylitol, calcium carbonate (CaCO3), sorbitol, sodium lauryl sulphate (SLS), natrium benzoate. Data analysis using one-way ANOVA test with normality test using Shapiro-Wilk and homogeneity test using Levene test. The results at a concentration of 20, 40, 60 and 80% with a positive control there was no significant difference because the sig value was >0.05. Results: The results showed that Celery containing toothpaste inhibits Streptococcus mutans growth (p value <0.05) that there is a significant inhibition effect of Apium graveolens L. extract toothpaste on the growth of Streptococcus mutans. Conclusion: There is an inhibition effect of celery leaf (Apium graveolens L.) extract toothpaste on the growth of Streptococcus mutans.Keywords: streptococcus mutans ATCC 25175, inhibition, toothpaste, celery, apium graveolens L
{"title":"Antibacterial potential of celery leaf extract toothpaste on the growth of Streptococcus mutans ATCC 25175","authors":"Maul Hayati, Fitria Mailiza, Shifa Khumaira Savitri","doi":"10.24198/pjd.vol35no1.30624","DOIUrl":"https://doi.org/10.24198/pjd.vol35no1.30624","url":null,"abstract":"ABSTRACTIntroduction: Celery (Apium graveolens L.) is a member of the Apiaceae family that can grow everywhere. Celery contains flavonoids, saponins, tannins, essential oils, apigenin, choline, vitamins A, B, C, asparagine bitter substances. Celery contains flavonoids, saponins, and tannins which are antibacterial compounds. Streptococcus mutans is a Gram-positive bacterium creating an acidic atmosphere in the oral cavity, which causes insufficient saliva to prevent enamel demineralisation which can lead to dental caries. The purpose of this study was to analyze the inhibition effect of celery leaf extract (Apium graveolens L.) on the growth of Streptococcus mutans. Methods: This type of experimental laboratory research uses the Post Test Only Control Group Design. The samples were Apium graveolens L. and Streptococcus mutans ATCC 25175. The number of treatment groups was 24 with concentrations of 20, 40, 60, and 80%. Toothpaste containing antibacterial ingredients was used as positive control and for negative control, a basic toothpaste formula without antibacterial ingredients, namely carboxymethyl cellulose (CMC), xylitol, calcium carbonate (CaCO3), sorbitol, sodium lauryl sulphate (SLS), natrium benzoate. Data analysis using one-way ANOVA test with normality test using Shapiro-Wilk and homogeneity test using Levene test. The results at a concentration of 20, 40, 60 and 80% with a positive control there was no significant difference because the sig value was >0.05. Results: The results showed that Celery containing toothpaste inhibits Streptococcus mutans growth (p value <0.05) that there is a significant inhibition effect of Apium graveolens L. extract toothpaste on the growth of Streptococcus mutans. Conclusion: There is an inhibition effect of celery leaf (Apium graveolens L.) extract toothpaste on the growth of Streptococcus mutans.Keywords: streptococcus mutans ATCC 25175, inhibition, toothpaste, celery, apium graveolens L","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41937414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.24198/pjd.vol35no1.41996
Sectio Aprista, S. Nelis, Avina Anin Nasia, Y. B. Prabowo
ABSTRACTIntroduction: One of type 2 diabetes mellitus oral manifestations is xerostomia. Xerostomia can cause various problems, such as difficulty of eating, chewing and swallowing, so that it can affect the quality of life. The aim of this research is to analyze the effect of xerostomia on the quality of life of controlled and uncontrolled type 2 diabetes mellitus patients. Methods: This analytical observational cross-sectional study involving 92 subjects from type 2 diabetes mellitus patients aged 21 to 50 years (Patients of controlled and uncontrolled type 2 diabetes mellitus 46 subjects each). Xerostomia data was collected by Summated Xerostomia Inventory-Dutch Version questionnaire, while the quality of life data was collected by Xerostomia-related Quality of Life Scale (XeQoLs) questionnaire. All research data were analyzed descriptively and bivariate analysis with Chi-Square test. Results: The results showed that the quality of life of controlled and uncontrolled type 2 diabetes mellitus patients was equally low (50% in controlled type 2 DM patients and 64.9% in uncontrolled type 2 DM patients). This result showed that there is no difference between each subject groups. This also can be seen from the results of statistical tests that p = 0.193 (p>0.05), which means that there is no significant difference between the quality of life of controlled and uncontrolled type 2 diabetes mellitus patients. Conclusion: There was no effect between xerostomia of controlled and uncontrolled type 2 DM patients with their quality of life.Keywords: type 2 diabetes mellitus, xerostomia-related to quality of life, xerostomia
{"title":"The effect of xerostomia on the quality of life of controlled and uncontrolled type 2 diabetes mellitus patients","authors":"Sectio Aprista, S. Nelis, Avina Anin Nasia, Y. B. Prabowo","doi":"10.24198/pjd.vol35no1.41996","DOIUrl":"https://doi.org/10.24198/pjd.vol35no1.41996","url":null,"abstract":"ABSTRACTIntroduction: One of type 2 diabetes mellitus oral manifestations is xerostomia. Xerostomia can cause various problems, such as difficulty of eating, chewing and swallowing, so that it can affect the quality of life. The aim of this research is to analyze the effect of xerostomia on the quality of life of controlled and uncontrolled type 2 diabetes mellitus patients. Methods: This analytical observational cross-sectional study involving 92 subjects from type 2 diabetes mellitus patients aged 21 to 50 years (Patients of controlled and uncontrolled type 2 diabetes mellitus 46 subjects each). Xerostomia data was collected by Summated Xerostomia Inventory-Dutch Version questionnaire, while the quality of life data was collected by Xerostomia-related Quality of Life Scale (XeQoLs) questionnaire. All research data were analyzed descriptively and bivariate analysis with Chi-Square test. Results: The results showed that the quality of life of controlled and uncontrolled type 2 diabetes mellitus patients was equally low (50% in controlled type 2 DM patients and 64.9% in uncontrolled type 2 DM patients). This result showed that there is no difference between each subject groups. This also can be seen from the results of statistical tests that p = 0.193 (p>0.05), which means that there is no significant difference between the quality of life of controlled and uncontrolled type 2 diabetes mellitus patients. Conclusion: There was no effect between xerostomia of controlled and uncontrolled type 2 DM patients with their quality of life.Keywords: type 2 diabetes mellitus, xerostomia-related to quality of life, xerostomia","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44261665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.24198/pjd.vol35no1.42892
Chita Sintya Dewi, R. Primarti, I. Sasmita
ABSTRACTIntroduction: Dental caries is a multifactorial disease that invades the hard tissues of the teeth. Dental caries is among the most common oral manifestations in children with autism spectrum disorders (ASD). ASD is a neurodevelopmental disorder characterized by deficits in social interactions, communication difficulties, and restricted repetitive behavior. ASD children have a higher risk of dental caries due to their difficulty maintaining good oral hygiene and poor diet, such as having a high preference for cariogenic foods. This study aims to analyze the association between cariogenic foods consumption frequency and the occurrence of dental caries in ASD children. Methods: Quantitative study was performed with a cross-sectional design and total sampling techniques on 15 ASD children. Data analysis using Spearman Rank test. Results: This study found (66,7%) of ASD children had low levels of cariogenic foods consumption. Respectively, the ASD children’s deft and DMFT indices were (3.3) and (4.4). A significant value between the frequency of consumption of cariogenic foods and DMFT/deft was (0.297). The level of relationship between the frequency of consumption of cariogenic foods with DMFT/deft is (0.289), indicating a low association. Conclusions: There is no association between cariogenic foods consumption frequency and the occurrence of dental caries in children with ASD. The average indices of DMFT and deft of ASD children are at moderate levels. ASD children have low levels of cariogenic food consumption frequency.Keywords: Autism Spectrum Disorder (ASD), Cariogenic Foods, Dental Caries.
{"title":"The association of cariogenic foods consumption frequency on the occurrence of dental caries in children with autism spectrum disorders","authors":"Chita Sintya Dewi, R. Primarti, I. Sasmita","doi":"10.24198/pjd.vol35no1.42892","DOIUrl":"https://doi.org/10.24198/pjd.vol35no1.42892","url":null,"abstract":"ABSTRACTIntroduction: Dental caries is a multifactorial disease that invades the hard tissues of the teeth. Dental caries is among the most common oral manifestations in children with autism spectrum disorders (ASD). ASD is a neurodevelopmental disorder characterized by deficits in social interactions, communication difficulties, and restricted repetitive behavior. ASD children have a higher risk of dental caries due to their difficulty maintaining good oral hygiene and poor diet, such as having a high preference for cariogenic foods. This study aims to analyze the association between cariogenic foods consumption frequency and the occurrence of dental caries in ASD children. Methods: Quantitative study was performed with a cross-sectional design and total sampling techniques on 15 ASD children. Data analysis using Spearman Rank test. Results: This study found (66,7%) of ASD children had low levels of cariogenic foods consumption. Respectively, the ASD children’s deft and DMFT indices were (3.3) and (4.4). A significant value between the frequency of consumption of cariogenic foods and DMFT/deft was (0.297). The level of relationship between the frequency of consumption of cariogenic foods with DMFT/deft is (0.289), indicating a low association. Conclusions: There is no association between cariogenic foods consumption frequency and the occurrence of dental caries in children with ASD. The average indices of DMFT and deft of ASD children are at moderate levels. ASD children have low levels of cariogenic food consumption frequency.Keywords: Autism Spectrum Disorder (ASD), Cariogenic Foods, Dental Caries.","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42948072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACTIntroduction: Incision wounds are injuries caused by dental surgery procedures. Suturing is the gold standard for post-incision management, but it can cause patient discomfort. Tissue glue can be used for wound healing, but its carcinogenicity still needs to be investigated. A Wound Healing Sheet (WHS) made of Aloe vera extract and free-range chicken egg albumin is expected to be an alternative material. Angiogenesis is a highly observable part of wound healing, as newly formed blood vessels support nutrition, act as a scaffold for cells to migrate to the wound area, and play an essential role in wound healing. This study aimed to analyze the effect of WHS made from Aloe vera extract and free-range chicken egg albumin (Gallus domesticus) on the number of vascular that show the acceleration of healing in gingival incision wounds. Methods: Quasi experimental study with a total sample of 24 male rats (Rattus norvegicus Wistar strain) with gingival incision were divided into four groups, namely T1 (50% WHS treated group), T2 (100% WHS treated group, S (suturing treated group as positive control), and NC (negative control, without treatment). The treatment was performed throughout seven days. The data obtained were analyzed statistically using One-way ANOVA and Post Hoc LSD. Results: The highest vascular count was in the T2 Group (8+1.63); followed by T1 (7+1.60); S (7+ 1.49); and NC (4+1.41). Statistical analysis showed that there was a significant difference between groups S, T1, T2 with NC (p-value < 0.05); interestingly, there was no significant difference between S, T1, T2 (p-value > 0.05). Conclusion: Wound Healing Sheet made of Aloe vera extract and free-range chicken egg albumin (Gallus domesticus) can accelerate the angiogenesis process on gingival incision wound in rats.Keywords: wound healing, aloe vera, gallus domesticus, egg white, angiogenesis
{"title":"Aloe vera extract wound healing sheet and free-range chicken egg albumin (gallus domesticus) accelerate angiogenesis on gingival incision wound in rats","authors":"Myrna Evana Amanda Putri, Christiana Cahyani Prihastuti, Mutia Rochmawati, Alya Ghina Rosyada, Wizni A'dila A'ziza","doi":"10.24198/pjd.vol35no1.42775","DOIUrl":"https://doi.org/10.24198/pjd.vol35no1.42775","url":null,"abstract":"ABSTRACTIntroduction: Incision wounds are injuries caused by dental surgery procedures. Suturing is the gold standard for post-incision management, but it can cause patient discomfort. Tissue glue can be used for wound healing, but its carcinogenicity still needs to be investigated. A Wound Healing Sheet (WHS) made of Aloe vera extract and free-range chicken egg albumin is expected to be an alternative material. Angiogenesis is a highly observable part of wound healing, as newly formed blood vessels support nutrition, act as a scaffold for cells to migrate to the wound area, and play an essential role in wound healing. This study aimed to analyze the effect of WHS made from Aloe vera extract and free-range chicken egg albumin (Gallus domesticus) on the number of vascular that show the acceleration of healing in gingival incision wounds. Methods: Quasi experimental study with a total sample of 24 male rats (Rattus norvegicus Wistar strain) with gingival incision were divided into four groups, namely T1 (50% WHS treated group), T2 (100% WHS treated group, S (suturing treated group as positive control), and NC (negative control, without treatment). The treatment was performed throughout seven days. The data obtained were analyzed statistically using One-way ANOVA and Post Hoc LSD. Results: The highest vascular count was in the T2 Group (8+1.63); followed by T1 (7+1.60); S (7+ 1.49); and NC (4+1.41). Statistical analysis showed that there was a significant difference between groups S, T1, T2 with NC (p-value < 0.05); interestingly, there was no significant difference between S, T1, T2 (p-value > 0.05). Conclusion: Wound Healing Sheet made of Aloe vera extract and free-range chicken egg albumin (Gallus domesticus) can accelerate the angiogenesis process on gingival incision wound in rats.Keywords: wound healing, aloe vera, gallus domesticus, egg white, angiogenesis","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48129323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.24198/pjd.vol35no1.36563
Nyoman Ayu Anggayanti, Putu Lestari Sudirman, Ni Nyoman Rian Permata Sari, I. G. A. P. D. Suryani
ABSTRACTIntroduction: Tooth extraction can cause the damage of hard and soft tissue. When an injury occurs, fibroblast will respond in the wound healing process. Herbal medicines such as green tea and chitosan can be used in wound healing. The polyphenol content in green tea, namely EGCG, has an anti-inflammatory effect, increasing wound healing. In wound healing, chitosan promotes hemostasis and tissue recovery. Based on several previous studies, the use of 1.2% green tea extract was effective for improving wound healing in rat open wound models, chitosan 1% could trigger the proliferation of fibroblasts in the wound healing process after tooth extraction. The aim of this study is to analyze the effect of gel mixture of extract Camellia sinensis 1,2% with chitosan 1% on post-tooth extraction wound of Wistar rats. Methods: This was a randomized post-test only control group design using 40 Wistar rats which were randomly divided into 2 groups. Each group underwent intramuscular anesthesia on the rat's thigh and tooth extraction of mandibular left incisor. The treatment group was applied mixed gel of extract Camellia sinensis 1.2% and 1% chitosan as much as 0.01 ml and the control group was not given any treatment, after that decapitated on days 1, 3, 5, and 7. Result: The mean number of treated fibroblasts was higher than the control group on days 1, 3, 5, 7, respectively, 75.00; 176.00; 349.00 and 427.00 cells. The mean difference in the number of fibroblasts was significant with p-value 0.001 (p>0.05). Conclusions: Mixed extract gel of Camellia sinensis and chitosan increased fibroblasts in wound healing process after tooth extraction of Wistar rats with the highest mean of fibroblast on the 7th day.Keywords: mixed tea leaves,chitosan, fibroblast,wound healing
{"title":"Effectiveness of mixed tea plant extract gel with chitosan on fibroblast cells after tooth extraction of Wistar rats","authors":"Nyoman Ayu Anggayanti, Putu Lestari Sudirman, Ni Nyoman Rian Permata Sari, I. G. A. P. D. Suryani","doi":"10.24198/pjd.vol35no1.36563","DOIUrl":"https://doi.org/10.24198/pjd.vol35no1.36563","url":null,"abstract":"ABSTRACTIntroduction: Tooth extraction can cause the damage of hard and soft tissue. When an injury occurs, fibroblast will respond in the wound healing process. Herbal medicines such as green tea and chitosan can be used in wound healing. The polyphenol content in green tea, namely EGCG, has an anti-inflammatory effect, increasing wound healing. In wound healing, chitosan promotes hemostasis and tissue recovery. Based on several previous studies, the use of 1.2% green tea extract was effective for improving wound healing in rat open wound models, chitosan 1% could trigger the proliferation of fibroblasts in the wound healing process after tooth extraction. The aim of this study is to analyze the effect of gel mixture of extract Camellia sinensis 1,2% with chitosan 1% on post-tooth extraction wound of Wistar rats. Methods: This was a randomized post-test only control group design using 40 Wistar rats which were randomly divided into 2 groups. Each group underwent intramuscular anesthesia on the rat's thigh and tooth extraction of mandibular left incisor. The treatment group was applied mixed gel of extract Camellia sinensis 1.2% and 1% chitosan as much as 0.01 ml and the control group was not given any treatment, after that decapitated on days 1, 3, 5, and 7. Result: The mean number of treated fibroblasts was higher than the control group on days 1, 3, 5, 7, respectively, 75.00; 176.00; 349.00 and 427.00 cells. The mean difference in the number of fibroblasts was significant with p-value 0.001 (p>0.05). Conclusions: Mixed extract gel of Camellia sinensis and chitosan increased fibroblasts in wound healing process after tooth extraction of Wistar rats with the highest mean of fibroblast on the 7th day.Keywords: mixed tea leaves,chitosan, fibroblast,wound healing","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47400236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.24198/pjd.vol35no1.33566
Retno Hayati Alchusnah, Dewi Sarastuti, Lia Fetti Hidayati, Fatimah Septiantari, Belladina Yusi Lasara
ABSTRACTIntroduction: The emergence of COVID-19 pandemic that occurred at the end of December 2019 in Wuhan, China, was a health crisis that greatly affected the world. Therefore, dentists and dental nurses are professionals who have a very high risk of being exposed to the droplets and aerosol particles generated during dental procedures. Furthermore, they also have a high risk of cross-infection from exposure to microorganisms in blood, saliva, droplets, and instruments contaminated with blood, saliva, and tissue debris. This study aims to analyze the effectiveness of using exhaust fan wall/Local Exhaust Ventilation (LEV), HEPA filter, and dental aerosol suction in the dental clinic of Academic Hospital Gadjah Mada University. Methods: The type of the research is analytical observational study. This study measured temperature, humidity, ACH and the microbial load in the 3 dental clinic rooms of Sadewa 1 RSA UGM in September 2020, using an analytical observational method with ANOVA to determine the effect of using a LEV, HEPA filter and dental aerosol suction in the dental clinic. Results: Dental clinic equipped with a LEV, HEPA filter, and dental aerosol suction, was negatively associated with room humidity levels, with a Pearson correlation of (-0.777), air humidity correlated with microbial load (0.242), but the correlation was not large. From the ANOVA results, the use of LEV, HEPA filter and dental aerosol suction against humidity has a significant effect on reducing the humidity in the dental clinic with p value 0.05. Conclusion: The use of an oral LEV, HEPA filter, and dental aerosol suction has an effect on reducing air humidity and decreasing the microbial load, affects the number of particles or droplets in dental clinics, and affects ACH.Keywords: local exhaust ventilation, HEPA filter and dental aerosol suction, microbial load, humidity
{"title":"The effectiveness of using local exhaust ventilation, HEPA filter, and dental aerosol suction on indoor air quality","authors":"Retno Hayati Alchusnah, Dewi Sarastuti, Lia Fetti Hidayati, Fatimah Septiantari, Belladina Yusi Lasara","doi":"10.24198/pjd.vol35no1.33566","DOIUrl":"https://doi.org/10.24198/pjd.vol35no1.33566","url":null,"abstract":"ABSTRACTIntroduction: The emergence of COVID-19 pandemic that occurred at the end of December 2019 in Wuhan, China, was a health crisis that greatly affected the world. Therefore, dentists and dental nurses are professionals who have a very high risk of being exposed to the droplets and aerosol particles generated during dental procedures. Furthermore, they also have a high risk of cross-infection from exposure to microorganisms in blood, saliva, droplets, and instruments contaminated with blood, saliva, and tissue debris. This study aims to analyze the effectiveness of using exhaust fan wall/Local Exhaust Ventilation (LEV), HEPA filter, and dental aerosol suction in the dental clinic of Academic Hospital Gadjah Mada University. Methods: The type of the research is analytical observational study. This study measured temperature, humidity, ACH and the microbial load in the 3 dental clinic rooms of Sadewa 1 RSA UGM in September 2020, using an analytical observational method with ANOVA to determine the effect of using a LEV, HEPA filter and dental aerosol suction in the dental clinic. Results: Dental clinic equipped with a LEV, HEPA filter, and dental aerosol suction, was negatively associated with room humidity levels, with a Pearson correlation of (-0.777), air humidity correlated with microbial load (0.242), but the correlation was not large. From the ANOVA results, the use of LEV, HEPA filter and dental aerosol suction against humidity has a significant effect on reducing the humidity in the dental clinic with p value 0.05. Conclusion: The use of an oral LEV, HEPA filter, and dental aerosol suction has an effect on reducing air humidity and decreasing the microbial load, affects the number of particles or droplets in dental clinics, and affects ACH.Keywords: local exhaust ventilation, HEPA filter and dental aerosol suction, microbial load, humidity","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43914318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACTIntroduction: The bioactivity property of pulp capping materials is determined by the hydroxyl ion release ability, which may alter the environmental pH to become alkaline. Calcium silicate-based materials are antibacterial, able to induce reparative dentin and have a good bacteria-tight seal. The poor handling of calcium silicate-based materials can be overcome by adding resin, so the materials will be easier to handle. Therefore, the purpose of this study was to synthesize a mixture of Indonesian White Portland Cements - Bi2O3 – UDMA and analyzed its hydroxyl ion release ability. Methods: The Indonesian White Portland Cements - Bi2O3 mixture was prepared using the simple solution method and mixed with UDMA. The sample’s ability to release hydroxyl ions was measured using a pH meter and titration test. Results: This study showed that the mixture of Indonesian White Portland Cements - Bi2O3 - UDMA had an initial pH of 11.04 and increased to its peak on 168 hours mark, or on day seven, to pH 11,77 with hydroxyl ion release value of 10-2.23 Conclusion: The mixture of Indonesian White Portland Cements - Bi2O3 -UDMA had an alkaline pH, was able to release hydroxyl ion and had a potential to be used as a pulp capping material.Keywords: The mixture Indonesia White Portland Cements - Bi2O3 – UDMA, Hydroxyl ion, Release Ability
{"title":"Hydroxyl ion release ability from mixture of Indonesian White Portland Cements - Bi2O3 - Light Cured Methacrylate Based Resin as a Potential Pulp Capping Material","authors":"Denny Nurdin, Beactris Lamria Simanjuntak, Rahmi Alma Farah Adang, Arief Cahyanto","doi":"10.24198/pjd.vol35no1.43207","DOIUrl":"https://doi.org/10.24198/pjd.vol35no1.43207","url":null,"abstract":"ABSTRACTIntroduction: The bioactivity property of pulp capping materials is determined by the hydroxyl ion release ability, which may alter the environmental pH to become alkaline. Calcium silicate-based materials are antibacterial, able to induce reparative dentin and have a good bacteria-tight seal. The poor handling of calcium silicate-based materials can be overcome by adding resin, so the materials will be easier to handle. Therefore, the purpose of this study was to synthesize a mixture of Indonesian White Portland Cements - Bi2O3 – UDMA and analyzed its hydroxyl ion release ability. Methods: The Indonesian White Portland Cements - Bi2O3 mixture was prepared using the simple solution method and mixed with UDMA. The sample’s ability to release hydroxyl ions was measured using a pH meter and titration test. Results: This study showed that the mixture of Indonesian White Portland Cements - Bi2O3 - UDMA had an initial pH of 11.04 and increased to its peak on 168 hours mark, or on day seven, to pH 11,77 with hydroxyl ion release value of 10-2.23 Conclusion: The mixture of Indonesian White Portland Cements - Bi2O3 -UDMA had an alkaline pH, was able to release hydroxyl ion and had a potential to be used as a pulp capping material.Keywords: The mixture Indonesia White Portland Cements - Bi2O3 – UDMA, Hydroxyl ion, Release Ability","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41852237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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