Pub Date : 2022-11-30DOI: 10.24198/pjd.vol34no3.41509
Megananda Hiranya Putri, E. Julaeha, Eliza Herijulianti, N. Nurjanah
ABSTRACTIntroduction: Gingivitis is inflammation of the gingiva associated with bacterial activity in dental plaque. The combination of bay leaves and betel leaves infusion has been used as a toothbrush disinfectant. The purpose of this study was to obtain a stable and effective mouthwash formulation from the combination of both infusions to prevent and relieve gingivitis. Methods: Five mouthwash formulas were made by mixing the active ingredients which is a combination of bay leaves and betel leaves infusion, with additives. The combination namely F-I (100% : 0%); F-II (75% : 25%); F-III (50% : 50%); F-IV (25% : 75%) and F-V (0%: 100%). Antibacterial activity tests against Streptococcus mutans, Streptococcus sanguis, and Porphyromonas gingivalis and physical stability tests were carried out. Stability test was carried out by storing the formula at room temperature (280C), hot temperature (400C) and cold temperature (40C) for 3 storage cycles (6 weeks) and observing changes in the physical indicators of the solution, namely pH, specific gravity, viscosity and organoleptic conditions, namely homogeneity, clarity, color, aroma and taste at the end of every 2nd week. Results: F-I to F-V had no inhibitory activity against Streptococcus mutans and Streptococcus sanguis, but had inhibitory activity against Porphyromonas gingivalis in the range (7.19±0.48) to (8.29 ±0.82) mm (ANOVA with a significance value of 0.237 > 0.05). The 5 formulas were more stable at cold storage, with organoleptic observations at the end of the 3rd cycle showing a slight precipitate (+), clear solution, light brown color, mint aroma and sweet taste. F-II formulas showed better physical indicators values because they were closer to the standard values. Conclusion: The F-II formula is recommended as a mouthwash for gingivitis because significant for antibacterial effect and showed better physical indicators values as the standard values for herbal medicines.Keywords: antibacterial activity; bay leaves - betel leaves infusion; gingivitis; mouthwash formulation.
{"title":"Formulation of Mouthwash for Gingivitis from Combination Infusion of Salam leaves (Eugenia Polyantha Wight) and Betel leaf (Piper betle. L)","authors":"Megananda Hiranya Putri, E. Julaeha, Eliza Herijulianti, N. Nurjanah","doi":"10.24198/pjd.vol34no3.41509","DOIUrl":"https://doi.org/10.24198/pjd.vol34no3.41509","url":null,"abstract":"ABSTRACTIntroduction: Gingivitis is inflammation of the gingiva associated with bacterial activity in dental plaque. The combination of bay leaves and betel leaves infusion has been used as a toothbrush disinfectant. The purpose of this study was to obtain a stable and effective mouthwash formulation from the combination of both infusions to prevent and relieve gingivitis. Methods: Five mouthwash formulas were made by mixing the active ingredients which is a combination of bay leaves and betel leaves infusion, with additives. The combination namely F-I (100% : 0%); F-II (75% : 25%); F-III (50% : 50%); F-IV (25% : 75%) and F-V (0%: 100%). Antibacterial activity tests against Streptococcus mutans, Streptococcus sanguis, and Porphyromonas gingivalis and physical stability tests were carried out. Stability test was carried out by storing the formula at room temperature (280C), hot temperature (400C) and cold temperature (40C) for 3 storage cycles (6 weeks) and observing changes in the physical indicators of the solution, namely pH, specific gravity, viscosity and organoleptic conditions, namely homogeneity, clarity, color, aroma and taste at the end of every 2nd week. Results: F-I to F-V had no inhibitory activity against Streptococcus mutans and Streptococcus sanguis, but had inhibitory activity against Porphyromonas gingivalis in the range (7.19±0.48) to (8.29 ±0.82) mm (ANOVA with a significance value of 0.237 > 0.05). The 5 formulas were more stable at cold storage, with organoleptic observations at the end of the 3rd cycle showing a slight precipitate (+), clear solution, light brown color, mint aroma and sweet taste. F-II formulas showed better physical indicators values because they were closer to the standard values. Conclusion: The F-II formula is recommended as a mouthwash for gingivitis because significant for antibacterial effect and showed better physical indicators values as the standard values for herbal medicines.Keywords: antibacterial activity; bay leaves - betel leaves infusion; gingivitis; mouthwash formulation.","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41910355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-30DOI: 10.24198/pjd.vol34no3.39293
Flora Ng Lai Yi, E. Riyanti, Meirina Gartika
ABSTRACTIntroduction: Erosion is a common dental problem that is especially prevalent in children due to the increasing consumption of acidic food and beverages. APF gel is believed to be effective in reducing the demineralization effect of the teeth as well as escalating the remineralization process. This research aims to determine and evaluate the effectiveness of 1.23% APF gel as a preventive agent for the erosion of tooth enamel, specifically in deciduous teeth. Methods: This type of research is true experimental research. The population of this research would be primary teeth extracted from children, using a purposive sampling technique with inclusive and exclusive criteria. A total amount of 5 maxillary primary central incisors were extracted and cleaned. APF gel was applied repetitively on the left side of the teeth for 4 minutes every hour, whereas the right side was left as it is. Samples were then analyzed using a scanning electron microscope (SEM). A qualitative and subjective analysis regarding the micromorphological features of the erosion can be done. Result: The side of teeth without APF gel application has a greater erosion rate compared with teeth with APF gel application. The tooth which is demineralized shows a honeycomb structure of the interprismatic enamel. As for the dentinal tubules, teeth without APF gel application have a bigger opening of dentinal tubules, going up to 7.868 micrometers in size compared to teeth with APF gel application (1-2 micrometers). Conclusion: The application of professional acidulated phosphate fluoride (APF) gel on deciduous teeth even when soaked in Citrus aurantifolia, is proven to be effective in preventing dental erosion.Keywords: acidulated phosphate fluoride (APF) gel; citrus aurantifolia; dental erosion; primary tooth
{"title":"The effect of acidulated phosphate fluoride (APF) gel against erosion on enamel microstructure of primary teeth which soaked with Citrus aurantifolia","authors":"Flora Ng Lai Yi, E. Riyanti, Meirina Gartika","doi":"10.24198/pjd.vol34no3.39293","DOIUrl":"https://doi.org/10.24198/pjd.vol34no3.39293","url":null,"abstract":"ABSTRACTIntroduction: Erosion is a common dental problem that is especially prevalent in children due to the increasing consumption of acidic food and beverages. APF gel is believed to be effective in reducing the demineralization effect of the teeth as well as escalating the remineralization process. This research aims to determine and evaluate the effectiveness of 1.23% APF gel as a preventive agent for the erosion of tooth enamel, specifically in deciduous teeth. Methods: This type of research is true experimental research. The population of this research would be primary teeth extracted from children, using a purposive sampling technique with inclusive and exclusive criteria. A total amount of 5 maxillary primary central incisors were extracted and cleaned. APF gel was applied repetitively on the left side of the teeth for 4 minutes every hour, whereas the right side was left as it is. Samples were then analyzed using a scanning electron microscope (SEM). A qualitative and subjective analysis regarding the micromorphological features of the erosion can be done. Result: The side of teeth without APF gel application has a greater erosion rate compared with teeth with APF gel application. The tooth which is demineralized shows a honeycomb structure of the interprismatic enamel. As for the dentinal tubules, teeth without APF gel application have a bigger opening of dentinal tubules, going up to 7.868 micrometers in size compared to teeth with APF gel application (1-2 micrometers). Conclusion: The application of professional acidulated phosphate fluoride (APF) gel on deciduous teeth even when soaked in Citrus aurantifolia, is proven to be effective in preventing dental erosion.Keywords: acidulated phosphate fluoride (APF) gel; citrus aurantifolia; dental erosion; primary tooth ","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41333795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-30DOI: 10.24198/pjd.vol34no3.39593
M. M. Damayanti, A. K. Sari, A. R. Furqaani
ABSTRACT Introduction: Cinnamomum burmannii is commonly used in the treatment and is thought to be an anti-inflammation medicinal herb that may hasten recovery. Lip wound healing is a critical need for aesthetic performance. The purpose of this study is to evaluate the efficacy of natural lip balm C. Burmannii has been shown to speed up the healing of incision wounds in rats (Rattus norvegicus). Methods: This research was carried out in the laboratory biomedical Faculty of Medicine, Universitas Islam Bandung. In twenty-seven male rats weighing 200-300 g, a lip mucous incision of 10 mm length and 4 mm depth was surgically created. Simple random sampling was used to divide the animals into three treatment groups based on wound treatment after lip incision (The control group applied distillation water, the first group applied a lip balm placebo/base, and the second group applied natural lip balm C. burmannii) and then divided into three observation times (days 3rd, 7th, and14th). A lip biopsy was performed during each observation time to determine the success of the therapy. The macroscopic examination was carried out by counting the number of lip wounds that were closed around, while the microscopic examination was carried out by counting epithelialization with a Leica microscope and image raster software. Result: The length of the lip wound has greatly decreased in the C. Burmannii group with a p-value of 0,048 (p<0.05, and epithelialization was comparable across the board. Conclusion: The use of Cinnamomum burmannii natural lip balm is effective in accelerating lip wound healing by bringing the lip wound closer together. Effectiveness of Natural lip balm Cinnamon (Cinnamomum burmannii) in accelerating the incision wound healing process in Rattus norvegicus.Keywords: natural lip balm cinnamomum burmannii; wound closer; epithelialization
{"title":"Effectiveness of natural lip balm cinnamon (Cinnamomum burmannii) in accelerating the incision wound healing process in rattus norvegicus","authors":"M. M. Damayanti, A. K. Sari, A. R. Furqaani","doi":"10.24198/pjd.vol34no3.39593","DOIUrl":"https://doi.org/10.24198/pjd.vol34no3.39593","url":null,"abstract":"ABSTRACT Introduction: Cinnamomum burmannii is commonly used in the treatment and is thought to be an anti-inflammation medicinal herb that may hasten recovery. Lip wound healing is a critical need for aesthetic performance. The purpose of this study is to evaluate the efficacy of natural lip balm C. Burmannii has been shown to speed up the healing of incision wounds in rats (Rattus norvegicus). Methods: This research was carried out in the laboratory biomedical Faculty of Medicine, Universitas Islam Bandung. In twenty-seven male rats weighing 200-300 g, a lip mucous incision of 10 mm length and 4 mm depth was surgically created. Simple random sampling was used to divide the animals into three treatment groups based on wound treatment after lip incision (The control group applied distillation water, the first group applied a lip balm placebo/base, and the second group applied natural lip balm C. burmannii) and then divided into three observation times (days 3rd, 7th, and14th). A lip biopsy was performed during each observation time to determine the success of the therapy. The macroscopic examination was carried out by counting the number of lip wounds that were closed around, while the microscopic examination was carried out by counting epithelialization with a Leica microscope and image raster software. Result: The length of the lip wound has greatly decreased in the C. Burmannii group with a p-value of 0,048 (p<0.05, and epithelialization was comparable across the board. Conclusion: The use of Cinnamomum burmannii natural lip balm is effective in accelerating lip wound healing by bringing the lip wound closer together. Effectiveness of Natural lip balm Cinnamon (Cinnamomum burmannii) in accelerating the incision wound healing process in Rattus norvegicus.Keywords: natural lip balm cinnamomum burmannii; wound closer; epithelialization","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45764930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-30DOI: 10.24198/pjd.vol34no3.39296
S. Nasroen, F. Meliawaty, Tichvy Tammama, Putri Indriani Prasdiaz, Tias Choirunnisa, A. Maskoen
ABSTRACTIntroduction: FOXE1 rs4460498 and GSTP-1 I105V gene polymorphisms are suspected of having a role in some of the non-syndromic cleft lip and palate (NS CLP) populations worldwide. This study aims to analyze FOXE1 rs4460498 and GSTP-1 I105V polymorphisms associated with NS CLP as the risk factor among Deutero Malay Subrace in Indonesia. Methods: This study was a case-control design, using samples from the venous blood of 102 NS CLP subjects and 102 healthy control subjects. After DNA was extracted, the PCR-RFLPs method was performed using TasI restriction enzyme on 100 blood samples of FOXE1 rs4460498 group and Alw26I restriction enzyme on 105 blood samples of the GSTP-1 I105V group. The Chi-Square test was used with the Kolmogorov Smirnov and Exact Fisher alternatives. Results: T mutant allele (OR= 0.926, p>0.05) and CT genotype (OR= 0.0, p>0.05) of FOXE1 rs4460498 and the G mutant allele (OR= 0.988,p>0.05) and AG genotype (OR= 0.675,p>0.05) of the GSTP-1 I105V are not the risks of NS CLP. Conclusion: FOXE1 rs4460498 and GSTP-1 I105V gene polymorphisms are not associated with non-syndromic cleft lip and palate among Deutero Malay Subrace in the Indonesian population.Key words: deutero malay; FOXE1 rs4460498; GSTP-1 I105V; NS CLP
{"title":"Analysis of FOXE1 rs4460498 and GSTP-1 I105V associated with non syndromic cleft lip and palate among Deutero Malay Subrace in Indonesia","authors":"S. Nasroen, F. Meliawaty, Tichvy Tammama, Putri Indriani Prasdiaz, Tias Choirunnisa, A. Maskoen","doi":"10.24198/pjd.vol34no3.39296","DOIUrl":"https://doi.org/10.24198/pjd.vol34no3.39296","url":null,"abstract":"ABSTRACTIntroduction: FOXE1 rs4460498 and GSTP-1 I105V gene polymorphisms are suspected of having a role in some of the non-syndromic cleft lip and palate (NS CLP) populations worldwide. This study aims to analyze FOXE1 rs4460498 and GSTP-1 I105V polymorphisms associated with NS CLP as the risk factor among Deutero Malay Subrace in Indonesia. Methods: This study was a case-control design, using samples from the venous blood of 102 NS CLP subjects and 102 healthy control subjects. After DNA was extracted, the PCR-RFLPs method was performed using TasI restriction enzyme on 100 blood samples of FOXE1 rs4460498 group and Alw26I restriction enzyme on 105 blood samples of the GSTP-1 I105V group. The Chi-Square test was used with the Kolmogorov Smirnov and Exact Fisher alternatives. Results: T mutant allele (OR= 0.926, p>0.05) and CT genotype (OR= 0.0, p>0.05) of FOXE1 rs4460498 and the G mutant allele (OR= 0.988,p>0.05) and AG genotype (OR= 0.675,p>0.05) of the GSTP-1 I105V are not the risks of NS CLP. Conclusion: FOXE1 rs4460498 and GSTP-1 I105V gene polymorphisms are not associated with non-syndromic cleft lip and palate among Deutero Malay Subrace in the Indonesian population.Key words: deutero malay; FOXE1 rs4460498; GSTP-1 I105V; NS CLP","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48180823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-30DOI: 10.24198/pjd.vol34no3.43255
Dr. Endang Sjamsudin, drg, Sp.BMMF, Subsp.TMF-TMJ[K], Arina Al Khaq, A. Yuza
ABSTRACTIntroduction: Odontectomy is a surgical procedure to remove an impacted tooth. Some cases of odontectomy are performed under general anesthesia because it has risks and complications that need to be considered, such as a patient with mental or physical disorder, difficulty level of the impacted tooth, number of impacted teeth extracted, and operative duration. This study aimed to determine the prevalence of post-odontectomy complications under general anesthesia in RSGM Universitas Padjadjaran Bandung. Methods: This study was a cross-sectional descriptive study using retrospective data of medical records of a patient who underwent odontectomy under general anesthesia from 2017 until 2018 in RSGM Unpad. Samples were taken using a purposive non-probability sampling technique by setting inclusion criteria such as undamaged medical records and providing patient data on the first and a week control visit. The variables, including age, gender, classification of impacted teeth, number of teeth, and complications, were assessed in this study. The minimum sample size was determined by using the Slovin formula. The minimum sample required is 94% - 95% confidence level and 5% margin of error. Result: The data that had been collected shows that the number of female patients (67%), male patients (37%), the most common age was 21-30 years (52%), and odontectomy in 4 third molars (73%). Odontectomy that performed on four third molars (73%) with the ordinary post odontectocmy complications found in the female patient, such as trismus (2%), prolonged pain (7%), edema (3%), paraesthesia (3%). Conclusion: The prevalence of post-odontectomy complications under general anesthesia in RSGM Universitas Padjadjaran Banding is relatively low.Keywords: prevalence; odontectomy; general anesthesia; complications; impacted tooth.
{"title":"Prevalence of post odontectomy complications under general anesthesia in Rumah Sakit Gigi Mulut Universitas Padjadjaran","authors":"Dr. Endang Sjamsudin, drg, Sp.BMMF, Subsp.TMF-TMJ[K], Arina Al Khaq, A. Yuza","doi":"10.24198/pjd.vol34no3.43255","DOIUrl":"https://doi.org/10.24198/pjd.vol34no3.43255","url":null,"abstract":"ABSTRACTIntroduction: Odontectomy is a surgical procedure to remove an impacted tooth. Some cases of odontectomy are performed under general anesthesia because it has risks and complications that need to be considered, such as a patient with mental or physical disorder, difficulty level of the impacted tooth, number of impacted teeth extracted, and operative duration. This study aimed to determine the prevalence of post-odontectomy complications under general anesthesia in RSGM Universitas Padjadjaran Bandung. Methods: This study was a cross-sectional descriptive study using retrospective data of medical records of a patient who underwent odontectomy under general anesthesia from 2017 until 2018 in RSGM Unpad. Samples were taken using a purposive non-probability sampling technique by setting inclusion criteria such as undamaged medical records and providing patient data on the first and a week control visit. The variables, including age, gender, classification of impacted teeth, number of teeth, and complications, were assessed in this study. The minimum sample size was determined by using the Slovin formula. The minimum sample required is 94% - 95% confidence level and 5% margin of error. Result: The data that had been collected shows that the number of female patients (67%), male patients (37%), the most common age was 21-30 years (52%), and odontectomy in 4 third molars (73%). Odontectomy that performed on four third molars (73%) with the ordinary post odontectocmy complications found in the female patient, such as trismus (2%), prolonged pain (7%), edema (3%), paraesthesia (3%). Conclusion: The prevalence of post-odontectomy complications under general anesthesia in RSGM Universitas Padjadjaran Banding is relatively low.Keywords: prevalence; odontectomy; general anesthesia; complications; impacted tooth.","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41382682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-30DOI: 10.24198/pjd.vol34no3.36703
F. Balafif, M. Satari, D. Dhianawaty
ABSTRACTIntroduction: Oral candidiasis is a fungal infection of the oral cavity that is caused by Candida albicans (C. albicans). Treatment of oral candidiasis usually uses topical agents such as nystatin, but it comes with side effects. Research on medicinal materials from plants can be an alternative to chemical drugs. It has increasingly become a concern such as the tuber of sarang semut (Myrmecodia pendens Merr. & L.M. Perry). The aim of the study is to determine the effect of ethyl acetate and hexane fractions of M. pendens against C. albicans. Methods: M. pendens methanol extract used maceration method. As much as 33 g concentrated M. pendens methanol extract was partitioned with a separating funnel based on the polarity of the substances to obtain ethyl acetate fraction. The minimum inhibitory concentration (MIC) procedure was carried out by the microdilution method and measured by an ELISA reader. The minimum fungicidal concentration (MFC) was obtained conclusively on Mueller Hinton agar media at concentrations above MIC of ethyl acetate fraction of M. pendens. Results: Ethyl acetate fraction had antifungal effect against C. albicans. The MIC and MFC of ethyl acetate fraction were 625 μg/ml and 1.250 μg/ml. Conclusion: Ethyl acetate fraction of M. pendens can inhibit the growth of C. albicans. M. pendens can be developed as the prevention agent of oral candidiasis.Keywords: antifungal; candida albicans; ethyl acetate fraction; Myrmecodia pendens
{"title":"Antifungal effect of ethyl acetate fraction of Sarang semut (Myrmecodia pendens Merr.& Perry) against Candida albicans","authors":"F. Balafif, M. Satari, D. Dhianawaty","doi":"10.24198/pjd.vol34no3.36703","DOIUrl":"https://doi.org/10.24198/pjd.vol34no3.36703","url":null,"abstract":"ABSTRACTIntroduction: Oral candidiasis is a fungal infection of the oral cavity that is caused by Candida albicans (C. albicans). Treatment of oral candidiasis usually uses topical agents such as nystatin, but it comes with side effects. Research on medicinal materials from plants can be an alternative to chemical drugs. It has increasingly become a concern such as the tuber of sarang semut (Myrmecodia pendens Merr. & L.M. Perry). The aim of the study is to determine the effect of ethyl acetate and hexane fractions of M. pendens against C. albicans. Methods: M. pendens methanol extract used maceration method. As much as 33 g concentrated M. pendens methanol extract was partitioned with a separating funnel based on the polarity of the substances to obtain ethyl acetate fraction. The minimum inhibitory concentration (MIC) procedure was carried out by the microdilution method and measured by an ELISA reader. The minimum fungicidal concentration (MFC) was obtained conclusively on Mueller Hinton agar media at concentrations above MIC of ethyl acetate fraction of M. pendens. Results: Ethyl acetate fraction had antifungal effect against C. albicans. The MIC and MFC of ethyl acetate fraction were 625 μg/ml and 1.250 μg/ml. Conclusion: Ethyl acetate fraction of M. pendens can inhibit the growth of C. albicans. M. pendens can be developed as the prevention agent of oral candidiasis.Keywords: antifungal; candida albicans; ethyl acetate fraction; Myrmecodia pendens","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49456922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.24198/pjd.vol34no2.41384
Aya Amida, Dudi Aripin, A. T. Hayati, F. Latief, Nina Djustiana, A. Cahyanto, Kosterman Usri, S. Tjahajawati, M. S. Mariam, Sunardhi Widyaputra
ABSTRACT Introduction: Root canal filling is an important part of root canal treatment that aimed to seal the root canal system, to prevent bacterial penetration and their toxins into periradicular tissues and to provide favourable environment for periapical healing. Thermoplasticized technique were developed to produce filling with homogenous mass, to achieve optimal sealing ability and to increase the quality of root canal filling. The aim of this study is to analyzed differences of Micro-Computed Tomography (Micro-CT) evaluation of the obturation sealing capability between thermoplastic carrier-based condensing techniques and lateral heat condensation techniques. Methods: This study was conducted under an in-vitro quasi experimental methode to 36 specimens of maxillaris centralis incisivus which were divided to 3 groups, (A) thermoplasticized carrier-based technique (GuttaCore System), (B) warm lateral condensation technique (heat carrier SystemB), (C) cold lateral condensation as control group. Sealing ability is evaluated based on the measurement results of volume percentages of filling material and sealer, volume of void, and surface density, that which was calculated from the 3D volumetric image of Micro-CT device. Data were statistically analysed using Analisis of Variance (ANOVA) and t-test. Result: The result showed significant difference of percentage filling material and sealer volume in apical third (p<0.05), whereas there were no significant differences of void volume in apical third, middle third, coronal third or along the canal (p>0.05). Conclusion: Thermoplastized carrier-based technique is not better than warm lateral technique.Keywords: sealing ability; root canal filling; thermoplasticized carrier-based technique; warm lateral technique.
{"title":"Differences of Micro-CT evaluation of the obturation sealing capability between thermoplastic carrier-based condensing techniques and lateral heat condensation techniques","authors":"Aya Amida, Dudi Aripin, A. T. Hayati, F. Latief, Nina Djustiana, A. Cahyanto, Kosterman Usri, S. Tjahajawati, M. S. Mariam, Sunardhi Widyaputra","doi":"10.24198/pjd.vol34no2.41384","DOIUrl":"https://doi.org/10.24198/pjd.vol34no2.41384","url":null,"abstract":"ABSTRACT Introduction: Root canal filling is an important part of root canal treatment that aimed to seal the root canal system, to prevent bacterial penetration and their toxins into periradicular tissues and to provide favourable environment for periapical healing. Thermoplasticized technique were developed to produce filling with homogenous mass, to achieve optimal sealing ability and to increase the quality of root canal filling. The aim of this study is to analyzed differences of Micro-Computed Tomography (Micro-CT) evaluation of the obturation sealing capability between thermoplastic carrier-based condensing techniques and lateral heat condensation techniques. Methods: This study was conducted under an in-vitro quasi experimental methode to 36 specimens of maxillaris centralis incisivus which were divided to 3 groups, (A) thermoplasticized carrier-based technique (GuttaCore System), (B) warm lateral condensation technique (heat carrier SystemB), (C) cold lateral condensation as control group. Sealing ability is evaluated based on the measurement results of volume percentages of filling material and sealer, volume of void, and surface density, that which was calculated from the 3D volumetric image of Micro-CT device. Data were statistically analysed using Analisis of Variance (ANOVA) and t-test. Result: The result showed significant difference of percentage filling material and sealer volume in apical third (p<0.05), whereas there were no significant differences of void volume in apical third, middle third, coronal third or along the canal (p>0.05). Conclusion: Thermoplastized carrier-based technique is not better than warm lateral technique.Keywords: sealing ability; root canal filling; thermoplasticized carrier-based technique; warm lateral technique.","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42550795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.24198/pjd.vol34no2.40711
V. Takarini, L. Asri, Nina Djustiana, B. K. Hadi
ABSTRACTIntroduction: Organic fillers made from the green-synthesis process can be utilized in dental treatment due to their non-toxic characteristic of the oral environment. Dental fillers must be smaller to improve their mechanical, physical, and biological properties. Material processing and centrifugation contribute to the size of processed materials. This study evaluates the effect of different centrifugation speeds on the size and distribution of glutinous rice flour as organic dental filler. Methods: This experimental study uses glutinous rice flour suspended in water and then centrifuged at different speeds of 3000 and 6000 rpm compared to untreated glutinous rice flour as control. The particle size was examined using Scanning Electron Microscope (SEM) and Dynamic Light Scattering (DLS). Next, Fourier Transform Infra Spectroscopy (FTIR) and X-ray Diffraction (XRD) were performed to evaluate whether there were structure and crystallinity changes. Finally, the cytocompatibility of fillers was examined by a cell viability test. Results: Centrifugation of glutinous rice flour at 3000 rpm resulted in smaller average size particles, evenly distributed, and higher crystallinity than other groups. There were no changes in functional groups, as shown by FTIR spectra. However, the processed samples were more amorphous compared to the control. Importantly, the processed samples appeared to be non-toxic, with a range of cell viability of 82.75-86.67% after 24 h incubation. Conclusion: Centrifugation speed of 3000 rpm has decreased in size, and a more homogenous particle size of organic filler made from glutinous rice flour. Importantly, it improved the cytocompatibility of particles compared to untreated control. Altogether, we proposed this organic material as a new potential material in the dental application that can be further investigated. Keywords: centrifugation speed; size distribution; organic dental filler; glutinous rice flour
{"title":"Centrifugation effect on size distribution of organic dental filler made from glutinous rice flour","authors":"V. Takarini, L. Asri, Nina Djustiana, B. K. Hadi","doi":"10.24198/pjd.vol34no2.40711","DOIUrl":"https://doi.org/10.24198/pjd.vol34no2.40711","url":null,"abstract":"ABSTRACTIntroduction: Organic fillers made from the green-synthesis process can be utilized in dental treatment due to their non-toxic characteristic of the oral environment. Dental fillers must be smaller to improve their mechanical, physical, and biological properties. Material processing and centrifugation contribute to the size of processed materials. This study evaluates the effect of different centrifugation speeds on the size and distribution of glutinous rice flour as organic dental filler. Methods: This experimental study uses glutinous rice flour suspended in water and then centrifuged at different speeds of 3000 and 6000 rpm compared to untreated glutinous rice flour as control. The particle size was examined using Scanning Electron Microscope (SEM) and Dynamic Light Scattering (DLS). Next, Fourier Transform Infra Spectroscopy (FTIR) and X-ray Diffraction (XRD) were performed to evaluate whether there were structure and crystallinity changes. Finally, the cytocompatibility of fillers was examined by a cell viability test. Results: Centrifugation of glutinous rice flour at 3000 rpm resulted in smaller average size particles, evenly distributed, and higher crystallinity than other groups. There were no changes in functional groups, as shown by FTIR spectra. However, the processed samples were more amorphous compared to the control. Importantly, the processed samples appeared to be non-toxic, with a range of cell viability of 82.75-86.67% after 24 h incubation. Conclusion: Centrifugation speed of 3000 rpm has decreased in size, and a more homogenous particle size of organic filler made from glutinous rice flour. Importantly, it improved the cytocompatibility of particles compared to untreated control. Altogether, we proposed this organic material as a new potential material in the dental application that can be further investigated. Keywords: centrifugation speed; size distribution; organic dental filler; glutinous rice flour","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42446491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.24198/pjd.vol34no2.36566
A. Brahmanta, A. Maharani, B. S. B. Dewantara, R. Sigit, S. Sukaridhoto, Excel Daris Fadhillah
ABSTRACTIntroduction: Collecting dental data for odontogram in medical records is done chiefly conventionally and causes a lot of human errors. Disadvantages of the conventional method can be overcome by developing a server-based system to store medical information equipped with embedded artificial intelligence (AI), which can identify the patient’s dental condition using an intra-oral camera with the help of Deep Learning algorithms. It is essential to evaluate the usability of this application to adapt to user needs. This study aimed to know the user’s experience in using this application and also provide information for improvements of the application. Methods: This is quantitative descriptive research with 15 users (dentists) as the respondent. The questionnaire was used to measure the user’s experience using this application. The user’s experiences measured are effectivity, efficiency, and satisfaction. Results: The highest scores of respondents on the three variables are extremely efficient, effective, and satisfied (9 people). The lowest score is slightly efficient and neutral on the efficiency and effectiveness variables (0 people). In the satisfaction variable, the lowest score is slightly satisfied (0 people). Conclusions: The Usability Testing of the “Smart Odontogram” Application based on User’s Experience showed a good result in 3 variables: effectiveness, efficiency, and satisfactionKeywords: smart Odontogram; medical record; application; usability testing; user’s experience
{"title":"Usability testing of “smart odontogram” application based on user’s experience","authors":"A. Brahmanta, A. Maharani, B. S. B. Dewantara, R. Sigit, S. Sukaridhoto, Excel Daris Fadhillah","doi":"10.24198/pjd.vol34no2.36566","DOIUrl":"https://doi.org/10.24198/pjd.vol34no2.36566","url":null,"abstract":"ABSTRACTIntroduction: Collecting dental data for odontogram in medical records is done chiefly conventionally and causes a lot of human errors. Disadvantages of the conventional method can be overcome by developing a server-based system to store medical information equipped with embedded artificial intelligence (AI), which can identify the patient’s dental condition using an intra-oral camera with the help of Deep Learning algorithms. It is essential to evaluate the usability of this application to adapt to user needs. This study aimed to know the user’s experience in using this application and also provide information for improvements of the application. Methods: This is quantitative descriptive research with 15 users (dentists) as the respondent. The questionnaire was used to measure the user’s experience using this application. The user’s experiences measured are effectivity, efficiency, and satisfaction. Results: The highest scores of respondents on the three variables are extremely efficient, effective, and satisfied (9 people). The lowest score is slightly efficient and neutral on the efficiency and effectiveness variables (0 people). In the satisfaction variable, the lowest score is slightly satisfied (0 people). Conclusions: The Usability Testing of the “Smart Odontogram” Application based on User’s Experience showed a good result in 3 variables: effectiveness, efficiency, and satisfactionKeywords: smart Odontogram; medical record; application; usability testing; user’s experience","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43508670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.24198/pjd.vol34no2.41242
R. Febrida, Madeiva Wulanhapsari, Yanwar Faza, E. Karlina, Arief Cahyanto, Solihudin Solihudin, Diana Rakhmawati Eddy
ABSTRACTIntroduction: Rice husk silica has been studied as a filler in dental composite, however, the mechanical properties of the resulting composites are below the commercial due to the poor surface modification between silica and resin matrix. 3-methacryloxyprpyltrimethoxysilane (MPTS) is one of the coupling agents that are effective to modify the silica surface. The purpose of this study to analyze the effect of MPTS on the diametral tensile strength (DTS) of the self-made composite using rice husk silica. Methods: The research type of this study was an experimental research laboratory. The samples (26 samples) were divided into two groups, namely the test group (using MPTS-modified silica) and the control group (using non-modified silica). The samples were cylindrical in shape with a diameter of 6.0 ± 0.1 mm and a height of 3.0 ± 0.1 mm according to ANSI/ADAS No. 27, 1993 and ISO 4049, 1988. The Fourier Transform Infrared (FTIR), HORIBA, was used to characterize the MPTS grafting on the silica surface. The DTS value is measured by Universal Testing Machine (UTM), Lloyd LRX Plus. Results: FTIR presents the additional peak of carboxyl and methacryloyl group at 1716, 1555, and 1410 cm-1 wavenumber, respectively in MPTS-modified silica. The DTS value of the test group was 43.40 ± 4.43 MPa and the control group was 25.80 ± 2.63 MPa. The test group was significantly higher than the control group (p-value = 0.001). Conclusion: The MPTS is effective to enhance the DTS value of rice husk silica-based composite.Keywords: Rice husk silica; dental composite; diametral tensile strength; 3-methacryloxypropyltrimethoxysilane.
{"title":"Effect of 3-methacryloxypropyltrimethoxysilane on diametral tensile strength of rice husk silica-based dental composite","authors":"R. Febrida, Madeiva Wulanhapsari, Yanwar Faza, E. Karlina, Arief Cahyanto, Solihudin Solihudin, Diana Rakhmawati Eddy","doi":"10.24198/pjd.vol34no2.41242","DOIUrl":"https://doi.org/10.24198/pjd.vol34no2.41242","url":null,"abstract":"ABSTRACTIntroduction: Rice husk silica has been studied as a filler in dental composite, however, the mechanical properties of the resulting composites are below the commercial due to the poor surface modification between silica and resin matrix. 3-methacryloxyprpyltrimethoxysilane (MPTS) is one of the coupling agents that are effective to modify the silica surface. The purpose of this study to analyze the effect of MPTS on the diametral tensile strength (DTS) of the self-made composite using rice husk silica. Methods: The research type of this study was an experimental research laboratory. The samples (26 samples) were divided into two groups, namely the test group (using MPTS-modified silica) and the control group (using non-modified silica). The samples were cylindrical in shape with a diameter of 6.0 ± 0.1 mm and a height of 3.0 ± 0.1 mm according to ANSI/ADAS No. 27, 1993 and ISO 4049, 1988. The Fourier Transform Infrared (FTIR), HORIBA, was used to characterize the MPTS grafting on the silica surface. The DTS value is measured by Universal Testing Machine (UTM), Lloyd LRX Plus. Results: FTIR presents the additional peak of carboxyl and methacryloyl group at 1716, 1555, and 1410 cm-1 wavenumber, respectively in MPTS-modified silica. The DTS value of the test group was 43.40 ± 4.43 MPa and the control group was 25.80 ± 2.63 MPa. The test group was significantly higher than the control group (p-value = 0.001). Conclusion: The MPTS is effective to enhance the DTS value of rice husk silica-based composite.Keywords: Rice husk silica; dental composite; diametral tensile strength; 3-methacryloxypropyltrimethoxysilane.","PeriodicalId":31757,"journal":{"name":"Padjadjaran Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43939866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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