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The current state of the issue of using cone beam computed tomography in the diagnosis of musculoskeletal diseases 使用锥形束计算机断层扫描诊断肌肉骨骼疾病的现状问题
Q4 Immunology and Microbiology Pub Date : 2023-12-12 DOI: 10.29413/abs.2023-8.5.20
N. Sholokhova, D. K. Zharkov, D. A. Lezhnev, A. Vasilyev, V. Petrovskaya, E. Y. Lazarenko, N. N. Blinov, A. D. Sergeeva
The high incidence rate and wide range of musculoskeletal pathologies determine the improvement of the diagnostic process. Late diagnosis leads to complications, which in turn increase the percentage of disability. Therefore, the search for the most informative method with the least radiation load on the patient remains an urgent problem for radiologists. Cone beam computed tomography (CBCT) is a modern and  promising technique that has already found wide application in dentistry and otorhinolaryngology. Among the advantages of CBCT are: three-dimensional image; high spatial resolution; low radiation dose. Thanks to technical improvements in equipment and the introduction of new image processing protocols, it has become possible to expand the indications for conducting the researches, including the researches based on imaging of the upper and lower extremities. Based on the results of a CBCT study, we can evaluate: the shape and contour of the bone; solution of continuity of the bone and malposition of bone fragments; the structure of bone tissue and  the  pathological processes occurring in it (destruction, osteoporosis, osteosclerosis); joint congruence and changes in  articular surfaces surrounding soft tissues. Therefore, CBCT can be introduced into the diagnostic process of bones and joints diseases. The use of this technique will find wide application in traumatology and orthopedics (fractures, dislocations, post-traumatic deformities, aseptic necrosis, osteoarthritis), rheumatology (rheumatoid arthritis, polyarthropathy, juvenile arthritis, gout), surgery (osteomyelitis), oncology (benign and malignant bone tumors) both in the adult population and in pediatric practice. This paper presents a review of the literature, which examines the degree of development of the issue of using CBCT and describes study protocols and protocols for processing the obtained images in the diagnosis of musculoskeletal diseases.
肌肉骨骼病变的高发病率和广泛性决定了诊断过程的改进。晚期诊断会导致并发症,进而增加致残率。因此,寻找对患者辐射负荷最小、信息量最大的方法仍然是放射科医生亟待解决的问题。锥形束计算机断层扫描(CBCT)是一种前景广阔的现代技术,已在牙科和耳鼻喉科得到广泛应用。CBCT 的优点包括:三维图像;高空间分辨率;低辐射剂量。由于设备技术的改进和新图像处理方案的引入,研究的适应症得以扩大,包括基于上下肢成像的研究。根据 CBCT 研究的结果,我们可以评估:骨的形状和轮廓;骨的连续性和骨碎片错位的解决方案;骨组织的结构及其发生的病理过程(破坏、骨质疏松症、骨硬化);关节的一致性和软组织周围关节面的变化。因此,CBCT 可以被引入骨骼和关节疾病的诊断过程中。该技术将广泛应用于创伤和矫形外科(骨折、脱位、创伤后畸形、无菌性坏死、骨关节炎)、风湿病学(类风湿性关节炎、多发性关节病、幼年关节炎、痛风)、外科(骨髓炎)、肿瘤学(良性和恶性骨肿瘤),包括成人和儿童。本文对文献进行了综述,探讨了使用 CBCT 问题的发展程度,并介绍了在诊断肌肉骨骼疾病时处理所获图像的研究方案和规程。
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引用次数: 0
Surgical treatment of massive rotator cuff tears (literature review) 大面积肩袖撕裂的手术治疗(文献综述)
Q4 Immunology and Microbiology Pub Date : 2023-12-12 DOI: 10.29413/abs.2023-8.5.22
D. V. Menshova
The prevalence of rotator cuff tears according to the literature ranges from 20 % to 40 %, and this injury occurs more often in people over 60 years of age. Massive rotator cuff tears account for 10–40 % of all rotator cuff tears. Massive rotator cuff tears are considered to be tears with a diastasis of more than 5 cm or tears involving two or more tendons. With such injuries, the kinematics of the shoulder joint changes: proximal subluxation of the humeral head and arthropathy of the shoulder joint occur, which subsequently causes pseudoparalysis. The main clinical manifestations are pain and dysfunction of the shoulder joint. Patients may experience a loss of active range of motion in the shoulder joint while maintaining passive range of motion. There is currently no unified approach to the choosing the tactics for surgical treatment. The most common options include partial rotator cuff repair, subacromial balloon plasty, replacement of tendon defects with allografts and autografts, proximal shoulder joint capsule plasty, muscle-tendon transfers, and shoulder joint arthroplasty. However, according to the literature data, the frequency of re-ruptures after surgery ranges from 11 % to 94 %. Despite the large number of methods for the treatment of massive rotator cuff tears, there are no clear algorithms for managing patients and choosing one or another surgical tactics. In addition, there is a high percentage of unsatisfactory outcomes of treatment. Taking all of these factors into account, the problem of improving the treatment of patients with massive rotator cuff tears remains relevant and timely.
根据文献记载,肩袖撕裂的发病率为 20% 至 40%,这种损伤更多发生在 60 岁以上的人群中。大面积肩袖撕裂占肩袖撕裂总数的 10%-40%。肩袖大面积撕裂被认为是指裂口间隙超过 5 厘米或撕裂涉及两条或两条以上肌腱。此类损伤会导致肩关节运动学发生变化:肱骨头近端半脱位和肩关节病变,进而引起假性瘫痪。主要临床表现为肩关节疼痛和功能障碍。患者在保持被动活动范围的同时,肩关节的主动活动范围可能会减小。在选择手术治疗策略方面,目前还没有统一的方法。最常见的方法包括肩袖部分修复术、肩峰下球囊成形术、同种异体或自体移植物肌腱缺损置换术、近端肩关节囊成形术、肌肉肌腱转移术和肩关节关节成形术。然而,根据文献数据,术后再次断裂的频率从 11% 到 94% 不等。尽管治疗肩袖大面积撕裂的方法很多,但在管理患者和选择手术策略方面却没有明确的算法。此外,治疗效果不理想的比例也很高。考虑到所有这些因素,如何改善对肩袖大面积撕裂患者的治疗仍然是一个重要而及时的问题。
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引用次数: 0
Restoration of X-ray bone density when replacing cortical plate defects with a tissue-engineered construct in the experiment 在实验中用组织工程构建物取代皮质板缺损,恢复 X 射线骨密度
Q4 Immunology and Microbiology Pub Date : 2023-12-12 DOI: 10.29413/abs.2023-8.5.25
E. Anastasieva, L. Cherdantseva, A. E. Medvedchikov, V. Lukinov, I. Kirilova
Over the past decade, in global practice, the frequency of using high-resolution multi-layer spiral computed tomography (MSCT) for assessing the state of cancellous and cortical bone tissue has significantly increased. Using high-resolution MSCT makes it possible to assess X-ray bone density at various times after replacement of cortical plate defects with osteoplastic materials. The aim of the research. To study the restoration of cortical bone density in the area of osteoplasty using tissue-engineered construct in the experiment. Materials and methods. In an in vivo experiment on New Zeland White (NZW) rabbits, perforation defects of cortical bone were formed in the femoral diaphysis. Three study groups were set up: group 1 – without bone defect replacement; group 2 – with  bone defect replacement with deproteinized cancellous bone; group  3  – with bone defect replacement with tissue-engineered construct based on deproteinized cancellous bone with stromal vascular fraction of adipose tissue. Follow-up periods were 2, 4 and 6 weeks after the surgery. The X-ray density of cortical bone tissue was measured in Hounsfield units (HU). Fragments of deproteinized human cancellous bone were used alone and in combination with the stromal vascular fraction of NZW rabbit adipose tissue as a bone-replacing material for bone defect replacement. Results. Cortical plate density the in the area of the defect in the group 3 by the week 6 is on average 1.3 times lower than that of the intact cortical plate and corresponds to D1 according to Misch classification. Cortical plate density in the area of the defect on the side of medullary canal by the week 6 in the group 3 corresponds to D1 according to Misch classification and is equal to 1351.25 ± 221.18 HU (1052; 1805), which is 1.5  times higher than in group  2 (D2 according to Misch classification; p < 0.05). The obtained results indicate an earlier restoration of X-ray bone density when using a tissue-engineered construct (group 3) compared to the same indicators in groups 1 and 2.
近十年来,在全球范围内,使用高分辨率多层螺旋计算机断层扫描(MSCT)评估松质骨和皮质骨组织状态的频率显著增加。使用高分辨率 MSCT 可以评估使用骨整形材料置换皮质板缺损后不同时期的 X 射线骨密度。研究目的在实验中使用组织工程构建物研究骨整形区域皮质骨密度的恢复情况。材料和方法。在对新西兰白兔(NZW)进行的体内实验中,在股骨头干骺端形成皮质骨穿孔缺损。实验分为三组:第 1 组--未进行骨缺损置换;第 2 组--使用去蛋白松质骨进行骨缺损置换;第 3 组--使用基于去蛋白松质骨和脂肪组织基质血管成分的组织工程构建物进行骨缺损置换。随访时间为术后 2 周、4 周和 6 周。皮质骨组织的 X 射线密度以 HU 为单位进行测量。单独使用或与 NZW 兔脂肪组织基质血管部分结合使用去蛋白人松质骨片段作为骨替代材料,用于骨缺损替代。结果显示第 6 周时,第 3 组缺损区域的皮质板密度平均是完整皮质板密度的 1.3 倍,根据 Misch 分级,相当于 D1。根据 Misch 分级,第 3 组第 6 周髓管侧缺损区的皮质板密度为 D1,等于 1351.25 ± 221.18 HU (1052; 1805),是第 2 组的 1.5 倍(根据 Misch 分级为 D2;P < 0.05)。所得结果表明,与第 1 组和第 2 组的相同指标相比,使用组织工程构建物(第 3 组)可更早地恢复 X 射线骨密度。
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引用次数: 0
Assessment of the effectiveness of surgical treatment of patients with massive tears of the rotator cuff tendons using arthroscopically assisted transposition of the latissimus dorsi tendon 利用关节镜辅助背阔肌肌腱转位手术治疗肩袖肌腱大面积撕裂患者的效果评估
Q4 Immunology and Microbiology Pub Date : 2023-12-11 DOI: 10.29413/abs.2023-8.5.14
D. V. Menshova, N. Ponomarenko, I. Kuklin, N. Tishkov, M. Puseva
Rotator cuff tears are one of the most common musculoskeletal injuries and account for about 20 %. Massive rotator cuff tears account for up to 40 % of all tears. There  is  no  single approach in the treatment of patients with massive rotator cuff tears. We have developed a new method of surgical treatment of these patients – arthroscopically assisted transposition of the latissimus dorsi tendon using 1/2 of the tendon of the long peroneal muscle. The aim of the study. To assess the effectiveness of surgical treatment of patients with massive rotator cuff tears who had arthroscopically assisted transposition of the latissimus dorsi tendon using an autograft of a 1/2 of the tendon of the long peroneal muscle. Materials and methods. The study included 15  patients with Patte stage  III and Thomazeau grade 2–3 massive rotator cuff tears, who had arthroscopically assisted transposition of the latissimus dorsi tendon using 1/2 of the tendon of the long peroneal muscle. Results. The article presents the long-term results of surgical treatment of patients using the developed method. The following criteria were evaluated: average age; time since injury; duration of surgery. Functional outcome was assessed using the ASES (American Shoulder and Elbow Surgeons) scale. Taking into account the indicators on the ASES functional scale 1 year after surgical treatment, the following results were obtained: excellent – in 14 (93.3 %) patients, satisfactory – in 1 (6.7 %) patient. Conclusion. The developed method allows us to restore the function of the shoulder joint as early as it possible, to reduce the severity of the pain syndrome and to improve the quality of life of patients.
肩袖撕裂是最常见的肌肉骨骼损伤之一,约占 20%。大面积肩袖撕裂占所有撕裂的 40%。目前还没有治疗肩袖大面积撕裂患者的单一方法。我们开发了一种治疗这类患者的新方法--利用长腓肠肌肌腱的 1/2,在关节镜辅助下转位背阔肌肌腱。研究目的评估使用长腓肠肌1/2肌腱的自体移植物在关节镜辅助下转位背阔肌肌腱的大面积肩袖撕裂患者的手术治疗效果。材料和方法。该研究纳入了 15 名 Patte III 期和 Thomazeau 2-3 级大面积肩袖撕裂的患者,他们都在关节镜辅助下使用 1/2的长腓肠肌肌腱进行了背阔肌肌腱转位。结果。文章介绍了使用该方法对患者进行手术治疗的长期结果。评估标准如下:平均年龄、受伤时间、手术时间。功能结果使用 ASES(美国肩肘外科医生)量表进行评估。根据手术治疗 1 年后 ASES 功能量表的各项指标,得出以下结果:14 名患者(93.3%)达到优秀,1 名患者(6.7%)达到满意。结论所开发的方法能让我们尽早恢复肩关节功能,减轻疼痛综合征的严重程度,提高患者的生活质量。
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引用次数: 0
Revision surgery for failure of the dynamic stabilization system of the lumbar spine 腰椎动态稳定系统失效的翻修手术
Q4 Immunology and Microbiology Pub Date : 2023-12-11 DOI: 10.29413/abs.2023-8.5.17
V. Potapov, S. Larionov, A. Zhivotenko, A. V. Gorbunov, V. Sorokovikov
The aim. To study the frequency and treatment options for dysfunction of the dynamic stabilization system of the lumbar spine. Materials and methods. We carried out a retrospective analysis of the treatment of 58  patients with degenerative pathology of the lumbar spine and instability of the spinal motion segments, who were treated at the neurosurgical unit of the Irkutsk Scientific Centre of Surgery and Traumatology in 2011–2020. The stability of spinal motion segment was assessed using X-ray imaging, magnetic resonance imaging and multi-layer spiral computed tomography of the lumbar spine. Revision surgery was performed in 7 out of 58 previously operated patients using the dynamic fixation system of spinal motion segments “Coflex” (Paradigm Spine LLC, Germany). Results. Revision surgery was performed in 7 out of 58 patients with dynamic fixation of the spinal motion segments with an interosseous implant due to an increase in pain syndrome. In 1 patient, the reason for repeated surgery was primary instability of the hardware caused by a fracture of the spinous process. In the delayed period, 4 patients had an X-ray picture with heterotopic ossification of the implant and instability of PDS. In two observations, a recurrence of intervertebral hernia was diagnosed at the level of the operated spinal motion segment. During revision surgery, a facetectomy was performed with stabilization by a peek cage, followed by pain management and clinical manifestation regression. Conclusion. The conducted study shows that a number of patients after discectomy and dynamic stabilization of the spine using “Coflex” system have inconsistency and  heterotypic ossification of  the implant and neoarthrosis. Implantation of a lumbar peek cage while maintaining the “Coflex” device makes it possible to form a rigid interbody fusion, which means it is sufficient and justified surgical technology for treating the failure of the dynamic stabilization system.
目的研究腰椎动态稳定系统功能障碍的发生频率和治疗方案。材料和方法。我们对2011-2020年间在伊尔库茨克外科和创伤学科学中心神经外科接受治疗的58名腰椎退行性病变和脊柱运动节段不稳定患者的治疗情况进行了回顾性分析。脊柱运动节段的稳定性是通过腰椎 X 射线成像、磁共振成像和多层螺旋计算机断层扫描进行评估的。在 58 名曾接受过手术的患者中,有 7 人使用脊柱运动节段动态固定系统 "Coflex"(德国 Paradigm Spine LLC 公司)进行了翻修手术。结果在 58 位使用骨间植入物动态固定脊柱运动节段的患者中,有 7 位患者因疼痛综合征加重而接受了翻修手术。1名患者重复手术的原因是棘突骨折导致的硬件原发性不稳定。在延迟期,4 名患者的 X 光片显示植入物异位骨化,PDS 不稳定。有两例患者被诊断出在手术脊柱运动节段复发了椎间孔疝。在翻修手术中,患者接受了面骨切除术,并用peek cage进行了稳定,随后进行了疼痛治疗,临床表现有所缓解。结论研究结果表明,一些患者在使用 "Coflex "系统进行椎间盘切除术和脊柱动态稳定术后,会出现植入物骨化不一致和异型化以及新关节病。在保留 "Coflex "装置的同时植入腰椎椎弓根,可以形成刚性椎体间融合,这意味着这是治疗动态稳定系统失效的充分、合理的手术技术。
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引用次数: 0
Forefoot reconstruction in brachymetatarsia 手足畸形前足重建术
Q4 Immunology and Microbiology Pub Date : 2023-12-11 DOI: 10.29413/abs.2023-8.5.19
I. Usoltsev, S. Leonova, M. Kosareva
Background. Brachymetatarsia is a rare disease characterized by abnormal shortening of one or more metatarsal bones. The clinical picture is most often dominated by complaints of aesthetic dissatisfaction, as well as pain in the forefoot caused by mechanical dysfunction. A radical way to solve the problem is surgical treatment. The aim. To demonstrate a rare clinical observation of a patient with bilateral brachymetatarsia of both feet. Materials and methods. The article presents a case of stepwise treatment of a patient with bilateral brachymetatarsia with shortening of the III and IV metatarsal bones in combination with hallux valgus. Results and discussion. According to the protocol, the patient underwent stepwise reconstruction of the forefoot of both feet with intervention on all five metatarsal bones. After all the rehabilitation measures, there was a complete restoration of all functions of both lower limbs after the surgery, and the patient was satisfied with the aesthetic result of the surgical treatment. Conclusions. The obtained result of treatment of a patient with bilateral brachymetatarsia allows us to conclude that the use of this group of techniques is acceptable with the obligatory preoperative calculation of the necessary shortening and lengthening of the metatarsal bones, focusing on the parameters of the metatarsal formula of the forefoot, even in combination with other deformities.
背景。跖跗关节病是一种罕见疾病,其特征是一个或多个跖骨异常缩短。临床表现主要是对美观的不满意,以及机械功能障碍导致的前足疼痛。解决问题的根本方法是手术治疗。目的是对一名双侧双足肱骨跖跗关节炎患者进行罕见的临床观察。材料和方法。文章介绍了一例双侧肱骨跖跗关节炎患者的分步治疗,该患者的Ⅲ和Ⅳ跖骨缩短,同时伴有拇指外翻。结果与讨论。根据治疗方案,患者接受了双足前掌的分步重建,并对所有五块跖骨进行了干预。在采取了所有康复措施后,术后患者双下肢的所有功能都得到了完全恢复,并且患者对手术治疗的美学效果表示满意。结论通过对一名双侧跖趾畸形患者的治疗结果,我们可以得出这样的结论:即使合并有其他畸形,在术前必须对跖骨进行必要的缩短和延长计算,重点关注前足跖骨公式的参数,使用这组技术也是可以接受的。
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引用次数: 0
The results of treatment of femoral diaphysis fractures using locked intramedullary osteosynthesis and extramedullary osteosynthesis (results for 10 years) 使用锁定髓内骨整合术和髓外骨整合术治疗股骨干骨折的结果(10 年结果)
Q4 Immunology and Microbiology Pub Date : 2023-12-11 DOI: 10.29413/abs.2023-8.5.18
V. G. Fedorov, I. V. Kuzin
Background. Femoral diaphysis fractures are one of the most common and significant injuries to the bones of the limbs. Locked intramedullary osteosynthesis makes it possible to reduce the injury rate of the surgery and its length, as well as to carry out early rehabilitation of patients. The aim of the study. To conduct a continuous retrospective single-purpose comparative study of  the results of treatment of patients with femoral diaphysis fractures treated with locked intramedullary osteosynthesis and extramedullary osteosynthesis for 10 years. This study did not include patients with double femoral fractures treated by osteosynthesis using a combination of two implants – locked intramedullary implant and extramedullary implant. Material and methods. We conducted a retrospective study of the results of treatment of patients from 2011 to 2020. During this period, we treated 794 patients aged from 16 to 77 years with femoral diaphysis fractures. The share of people of working age was 75 %. The patients were divided into two groups depending on the method of surgical treatment. Group 1 included 500 patients who had surgical treatment using locked intramedullary osteosynthesis. Group 2 included 294 patients who had surgical treatment using extramedullary osteosynthesis. Results. In patients of group 1 treated with locked intramedullary osteosynthesis, good anatomical and functional treatment results were achieved in 70 % of cases; satisfactory treatment results – in 25.2 % of cases, unsatisfactory results – in 4.8 %. In the group 2, good results were achieved in 61.9 % of cases, satisfactory – in 29.6 %, unsatisfactory – in 8.5 %. Conclusion. The obtained results of treatment of femoral diaphysis fractures show the undeniable advantage of using locked intramedullary osteosynthesis compared to extramedullary osteosynthesis.
背景。股骨干骺端骨折是四肢骨最常见、最严重的损伤之一。锁定髓内骨合成术可降低手术损伤率,缩短手术时间,并使患者尽早康复。研究目的对股骨头干骺端骨折患者使用锁定髓内骨整合术和髓外骨整合术治疗 10 年的结果进行连续回顾性单一目的比较研究。本研究不包括使用两种植入物(锁定髓内植入物和髓外植入物)组合进行骨合成治疗的双股骨骨折患者。材料和方法。我们对 2011 年至 2020 年期间患者的治疗结果进行了回顾性研究。在此期间,我们共治疗了 794 名股骨干骺端骨折患者,他们的年龄从 16 岁到 77 岁不等。其中工作年龄段的患者占 75%。根据手术治疗方法的不同,患者被分为两组。第一组包括 500 名使用锁定髓内骨合成术进行手术治疗的患者。第 2 组包括 294 名使用髓外骨合成术进行手术治疗的患者。结果在采用锁定髓内骨合成术治疗的第1组患者中,70%的病例在解剖和功能方面取得了良好的治疗效果;25.2%的病例取得了满意的治疗效果,4.8%的病例取得了不满意的治疗效果。在第二组中,61.9%的病例取得了良好的治疗效果,29.6%的病例取得了满意的治疗效果,8.5%的病例取得了不满意的治疗效果。结论股骨头干骺端骨折的治疗结果表明,与髓外骨连接相比,锁定髓内骨连接具有无可争议的优势。
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引用次数: 0
Acute kidney injury after primary total hip replacement 初级全髋关节置换术后急性肾损伤
Q4 Immunology and Microbiology Pub Date : 2023-12-11 DOI: 10.29413/abs.2023-8.5.13
M. L. Lebed, M. G. Kirpichenko, E. V. Novikova, T. G. Lebed, A. Mankov
Surgical interventions that do not directly affect the urinary system can cause excretory dysfunction of kidneys. The aim. To establish the prevalence, risk factors and clinical significance of acute kidney injury after primary hip replacement performed in the clinic of the Irkutsk Scientific Centre of Surgery and Traumatology. Materials and methods. We carried out a retrospective analysis of the case histories of 109 patients who underwent primary total hip replacement under conditions of subarachnoid anesthesia in the clinic of the Irkutsk Scientific Centre of Surgery and Traumatology in 2021. Results. Postoperative changes in serum creatinine in 8 patients of the study group met the KDIGO (The Kidney Disease: Improving Global Outcomes) criteria for acute kidney injury. Initial indicators of renal excretory function in the subgroup with acute kidney injury were not different from those in the entire group. Statistically significant correlation was established between acute kidney injury and indicators of oxygen-carrying capacity of blood – initial and minimal postoperative hemoglobin concentration. Acute kidney injury in patients of the study group had a minimal effect on the clinical course of the early postoperative period. None of the patients required renal replacement therapy, re-transfer from the specialized unit to the intensive care unit or any specific treatment. The duration of postoperative stay of patients with acute kidney injury in the clinic did not increase. Conclusions. Acute kidney injury was detected in 7.3  % of patients who underwent primary total hip replacement. Risk factors for the development of postoperative acute kidney injury in  patients of the study group included relatively low initial and  minimal postoperative blood hemoglobin concentrations, which may indicate prerenal mechanism of acute kidney injury pathogenesis. Implementation of the main steps of the “renal protocol” in patients with initial glomerular filtration rate over 45 ml/min/1.73 m2 allows avoiding the development of severe clinically significant forms of postoperative acute kidney injury and complications associated with it in the early postoperative period of primary total hip replacement.
不直接影响泌尿系统的外科手术可能会导致肾脏排泄功能障碍。目的是确定在伊尔库茨克外科和创伤学科学中心门诊进行初级髋关节置换术后急性肾损伤的发病率、风险因素和临床意义。材料和方法我们对 2021 年在伊尔库茨克外科和创伤学科学中心医院蛛网膜下腔麻醉条件下接受初级全髋关节置换术的 109 名患者的病史进行了回顾性分析。研究结果研究组中有8名患者的术后血清肌酐变化符合KDIGO(肾脏疾病:改善全球结果)急性肾损伤标准。急性肾损伤亚组患者肾脏排泄功能的初始指标与全组患者无差异。据统计,急性肾损伤与血液携氧能力指标--初始血红蛋白浓度和术后最低血红蛋白浓度--之间存在明显的相关性。研究组患者的急性肾损伤对术后早期的临床过程影响很小。没有一名患者需要进行肾脏替代治疗、从专科病房重新转入重症监护病房或接受任何特殊治疗。急性肾损伤患者的术后住院时间也没有延长。结论在接受初级全髋关节置换术的患者中,有7.3%发现了急性肾损伤。研究组患者发生术后急性肾损伤的风险因素包括初始血红蛋白浓度相对较低和术后血红蛋白浓度最低,这可能表明急性肾损伤的发病机制为肾前性疾病。对初始肾小球滤过率超过 45 毫升/分钟/1.73 平方米的患者实施 "肾脏治疗方案 "的主要步骤,可避免在原发性全髋关节置换术术后早期出现严重的临床意义上的术后急性肾损伤及其相关并发症。
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引用次数: 0
Rotator cuff tendon ruptures (literature review) 肩袖肌腱断裂(文献综述)
Q4 Immunology and Microbiology Pub Date : 2023-12-11 DOI: 10.29413/abs.2023-8.5.16
E. N. Slaykovskiy, N. Ponomarenko, I. Kuklin
Rotator cuff injury is a common pathology: up to 20 % of the population over 45 years of age has ruptures of varying severity, and up to 40 % of these ruptures are large and massive. The gradual development of tendon degeneration and fatty degeneration of muscle tissue and the asymptomatic course of the disease often lead to late medical attention when secondary arthropathy of the shoulder joint develops. With age, the probability of having a rupture increases, reaching 51 % in people over  80  years of age. The main diagnostic tools are radiography and  magnetic resonance imaging of the shoulder joint combined with clinical examination. Conservative treatment for massive injuries is ineffective, and the risk of worsening rotator cuff tendinopathy to rupture reaches 54 %. There are three main directions in the surgery of rotator cuff injuries: tendon reconstruction or replacement of their defect with grafts; muscle transfer; shoulder arthroplasty. Subacromial balloon spacer and tenogenic patches are also used. Each of these methods has a number of disadvantages and limitations. The frequency of repeated ruptures of reconstructed tendons reaches 45 %. Muscle transfer is extremely demanding on the skill of the surgeon and is associated with high risks of neurological complications. Arthroplasty imposes a number of significant restrictions on the patient, reducing the  quality of life, and prosthesis components wear increases the risk of complications, especially during revision interventions. The use of the subacromial spacer is limited by its high cost and lack of  long-term follow-up of treatment outcomes. Tenogenic patches have not undergone clinical trials, being an experimental technique. There is no single approach to the treatment of massive rotator cuff ruptures. The results are contradictory, the advantages of each of the methods are balanced by their disadvantages, which provides a wide window of opportunity in the studying, optimizing classical and introducing new methods of treatment of this pathology
肩袖损伤是一种常见的病理现象:在 45 岁以上的人群中,多达 20% 的人有不同程度的肩袖断裂,其中多达 40% 的人肩袖断裂面积大、范围广。肌腱变性和肌肉组织脂肪变性的逐渐发展以及无症状的病程往往会导致肩关节继发性关节病的发生,从而延误治疗。随着年龄的增长,发生断裂的概率也会增加,80 岁以上的老年人发生断裂的概率高达 51%。主要的诊断手段是对肩关节进行射线照相和磁共振成像,并结合临床检查。大面积损伤的保守治疗效果不佳,肩袖肌腱病变恶化至断裂的风险高达 54%。肩袖损伤手术有三个主要方向:肌腱重建或用移植物替代其缺损;肌肉转移;肩关节成形术。此外,还使用肩峰下气囊垫片和腱原贴片。这些方法都有一些缺点和局限性。重建肌腱反复断裂的频率高达 45%。肌肉转移对外科医生的技术要求极高,并伴有神经系统并发症的高风险。关节置换术给患者带来了许多重大限制,降低了生活质量,假体部件的磨损增加了并发症的风险,尤其是在翻修手术中。肩峰下垫片的使用因其高昂的费用和缺乏对治疗效果的长期跟踪而受到限制。腱鞘贴片作为一种实验性技术,尚未进行临床试验。目前还没有治疗肩袖大面积断裂的单一方法。结果是相互矛盾的,每种方法的优点都与缺点相平衡,这为研究、优化经典方法和引入新方法治疗该病症提供了广阔的机会。
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引用次数: 0
Microcirculation parameters of the damaged segment of the lower extremity after treatment of diaphyseal fractures using a locked intramedullary nail 使用锁定髓内钉治疗下肢骨骺骨折后受损段的微循环参数
Q4 Immunology and Microbiology Pub Date : 2023-12-11 DOI: 10.29413/abs.2023-8.5.15
A. I. Plakhov, L. Korytov, V. G. Vinogradov, M. Darenskaya, S. V. Makarov
Background. An in-depth analysis of the scientific works of scientists and medical practitioners allows us to conclude that locked nail intramedullary osteosynthesis is  the optimal and the most effective method of treating closed diaphyseal fractures of the lower leg bones, which is caused by the high stability of osteosynthesis and minimal damage to soft tissues during surgery. The processes of microcirculation changes in the early postoperative period by various metal structures, including a locked intramedullary nail, still remain unexplored. In particular, there is insufficient data on the use of a locked intramedullary nail. The aim of the study. To identify the features of changes in microcirculation indices of injured lower leg bones during fixation of fragments with a locked intramedullary nail in the early postoperative period. Materials and methods. The microcirculation of the lower limb segment was studied in 25 patients using laser Doppler flowmetry. Data from 25 healthy volunteers were used as a comparison group. Results. It was found that in the early postoperative period, from day 1 to day 10, in patients with diaphyseal fractures of the lower leg bones operated with locked nail intramedullary osteosynthesis, there is a decrease in the cardiac range, an increase in the share of the shunt component of microcirculation compared to the nutritional share, as well as an increase in more than 1 ratio of the cardiac and respiratory range amplitude, which indicates an ischemia type of local circulatory disorder. Compensation of ischemia is done by anastomoses, since the bypass rate is increased. Conclusion. In case of surgical treatment with locked nail intramedullary osteosynthesis, in the early postoperative period, an ischemic type of compensated local circulatory disorder develops. The regeneration process takes place under conditions of reduced arterial microcirculation blood flow and stable venous outflow, as well as the inclusion of anastomoses to compensate for destroyed vessels, which is associated with nail damage to the internal blood flow of the bone endosteum and intraosseous nutrient artery during the surgery.
背景。通过对科学家和医学工作者的科研成果进行深入分析,我们可以得出这样的结论:锁定髓内钉骨结合是治疗小腿骨闭合性骨骺骨折的最佳和最有效的方法,其原因在于骨结合的高度稳定性和手术过程中对软组织的最小损伤。包括锁定髓内钉在内的各种金属结构在术后早期的微循环变化过程仍未得到研究。尤其是关于使用带锁髓内钉的数据不足。研究目的确定术后早期使用带锁髓内钉固定碎片时受伤小腿骨微循环指数的变化特征。材料和方法使用激光多普勒血流测量仪对 25 名患者的下肢微循环进行了研究。25 名健康志愿者的数据作为对比组。结果研究发现,在术后早期,即从第 1 天到第 10 天,采用锁钉髓内植骨术的小腿骨干骺端骨折患者的心脏范围会缩小,微循环中分流成分所占比例与营养成分所占比例相比会增加,心脏和呼吸范围振幅的比值会超过 1,这表明局部循环障碍属于缺血类型。由于旁路速率增加,缺血可通过吻合得到补偿。结论在使用锁钉髓内骨合成术进行手术治疗的情况下,术后早期会出现缺血型代偿性局部循环障碍。再生过程是在动脉微循环血流减少和静脉流出稳定的条件下进行的,同时还需要吻合来补偿被破坏的血管,这与手术过程中骨内膜和骨内营养动脉的内钉损伤血流有关。
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引用次数: 0
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Acta Biomedica Scientifica
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