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Comparative study on the effects and complications of transverse insertion of two fine gauge quincke's spinal needles 26 and 29 G in spinal anesthesia 26、29g两根细径昆克脊髓针横插在脊髓麻醉中的效果及并发症比较研究
Pub Date : 2023-01-01 DOI: 10.4103/amit.amit_11_23
Becki Varghese, Ajay Wahi, G. Duggal, S. Bansal, Prabhdeep Singh, Manvi Garg
Introduction: Spinal anesthesia is one of the most commonly used techniques in modern anesthesia. Spinal needles have evolved over time to increase efficacy and decrease complications. Fine gauge spinal needles technically consume more time but are advisable in certain clinical conditions such as raised intracranial pressure and when patient well-being and comfort are the priorities. Hence, we undertook this study to compare the effects and complication of transverse insertion of Quincke's spinal needle 26 G (gauge) and 29 G. Materials and Methods: Hundred patients of age 18–40 years posted for lower abdominal and lower limb surgeries were allocated into two groups of 50 each to receive spinal anesthesia with 3 ml of 0.5% bupivacaine using 26 G or 29 G Quincke's spinal needle. All the patients were evaluated for the time of drug administration, number of attempts, time to attain sensory blockade up to T8 level, time to attain motor blockade up to bromage Grade 3, and incidence of post-dural puncture headache (PDPH) and post-dural puncture backache. Results: Demographic data were comparable in both groups. The PDPH incidence on 3rd day for 29 G Quincke's was 0% while for 26 G Quincke's was 12%. There was statistically significant difference when 26 G Quincke's was compared with 29 G Quincke's for number of attempts, time of drug administration, time to attain motor and sensory block. Conclusion: 29 G Quincke's spinal could be used to provide spinal anesthesia in young adult patients owing to adequate sensory and motor blockade with no incidence of PDPH and backache.
导读:脊髓麻醉是现代麻醉中最常用的技术之一。随着时间的推移,脊髓针已经发展到提高疗效和减少并发症。细径脊髓针在技术上消耗更多的时间,但在某些临床条件下是可取的,例如颅内压升高,以及当患者的健康和舒适是优先考虑的。因此,我们进行了这项研究,比较26g (gauge)和29g (29g)昆克脊髓针横向插入的效果和并发症。材料和方法:将100例18-40岁的下腹部和下肢手术患者分为两组,每组50人,分别使用26g或29g昆克脊髓针接受3ml 0.5%布比卡因的脊髓麻醉。评估所有患者的给药时间、尝试次数、达到T8级的感觉阻断时间、达到bromage 3级的运动阻断时间、硬膜穿刺后头痛(PDPH)和硬膜穿刺后背痛的发生率。结果:两组人口统计学数据具有可比性。29 G Quincke的第3天PDPH发生率为0%,26 G Quincke的第3天PDPH发生率为12%。26 G Quincke组与29 G Quincke组在尝试次数、给药时间、达到运动和感觉阻滞时间等方面比较,差异均有统计学意义。结论:29 G Quincke脊髓可用于青壮年患者的脊髓麻醉,其感觉和运动阻滞充分,且无PDPH和背痛的发生。
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引用次数: 0
Application of the milan system for reporting salivary gland cytology and risk stratification by cytohistological correlation 应用米兰系统报告唾液腺细胞学和细胞组织学相关性的风险分层
Pub Date : 2023-01-01 DOI: 10.4103/amit.amit_28_23
Zeeshan Iqbal, S. Rana, S. Khetrapal, Monal Trisal, N. Ahmed, S. Jetley, Arun Sharma, Z. Jairajpuri
Introduction: Salivary gland neoplasms are uncommon tumors comprising <3%–10% of all head-and-neck neoplasms. Recent WHO classification of salivary gland tumor added many newer entities; however, no definite risk-stratification system is specified to predict the likelihood of malignancy for each diagnostic category. The present study is designed to evaluate the salivary gland aspirates using the Milan System for Reporting Salivary Gland Cytology for reporting correlating with histological diagnosis which will lead to determine the malignancy risk for each diagnostic category. Risk of malignancy is calculated by the ratio of cytopathology cases with a malignant histopathology to the total number of cytopathology cases with follow-up histopathology for that particular category. Materials and Methods: The present study was a cross-sectional study done prospectively over a period of 2 years, and a total of 72 participants were selected. This study characterized the cytological features of spectrum of salivary gland lesions varying from benign to malignant. The lesions were evaluated and classified cytologically according to “the Milan System for Reporting Salivary Gland Cytopathology” for reporting salivary gland neoplasms. Histopathological correlation was done with cytological diagnosis wherever possible. Results: In our study of 72 patients with salivary gland lesions with the mean age of the patient being 50.6 years and maximum number of lesions involved the parotid gland followed by the submandibular gland and sublingual gland. Majority of the lesions in the present study were nonneoplastic in nature followed by lesions benign in nature. Malignant lesions were least common in occurrence. Among 72 cases, majority of the cases were seen in Milan category II (nonneoplastic) consisting of 34 cases (47.2%), followed by 31 cases (43.1%) in Milan category IV (benign). Final diagnostic categorization of 72 cases of salivary gland lesions was done according to the Milan system and the histopathological correlation was available in 23 of these cases. Out of the 34 cases in Milan system category II (nonneoplastic), histopathological evaluation was done in 2 cases. Both the cases were benign in nature, 31 cases in Milan system category IV (benign) histopathological evaluation was done in 16 cases where 15 cases were benign in nature and 1 lesion was malignant. Four cases were put in category VI of the Milan system, histopathological evaluation was done in all the 4 cases which were all malignant in nature. Conclusion: The current study validates fine-needle aspiration cytology as a cost-effective and noninvasive procedure for differentiating between benign and malignant lesions of the salivary gland, information of critical importance when determining the patient's next course of treatment.
唾液腺肿瘤是一种罕见的肿瘤,占头颈部肿瘤的3%-10%。世卫组织最近对唾液腺肿瘤的分类增加了许多新的实体;然而,没有明确的风险分层系统来预测每种诊断类别的恶性肿瘤的可能性。本研究旨在使用米兰系统报告唾液腺细胞学来评估唾液腺吸出物与组织学诊断的相关性,这将导致确定每种诊断类别的恶性肿瘤风险。恶性肿瘤的风险是通过具有恶性组织病理学的细胞病理学病例与该特定类别的随访组织病理学的细胞病理学病例总数的比率来计算的。材料和方法:本研究是一项前瞻性横断面研究,为期2年,共选择72名参与者。本研究描述了唾液腺良恶性病变的细胞学特征。根据报告唾液腺肿瘤的“米兰唾液腺细胞病理学报告系统”对病变进行评估和细胞学分类。尽可能将组织病理学与细胞学诊断相结合。结果:72例唾液腺病变患者,平均年龄50.6岁,病变最多的是腮腺,其次是下颌骨和舌下腺。在本研究中,大多数病变是非肿瘤性的,其次是良性的。恶性病变发生率最低。72例病例中,米兰ⅱ型(非肿瘤性)34例(47.2%),其次是米兰ⅳ型(良性)31例(43.1%)。根据米兰系统对72例唾液腺病变进行最终诊断分类,其中23例具有组织病理学相关性。在34例米兰系统II类(非肿瘤性)病例中,2例进行了组织病理学评估。两例均为良性,其中31例为米兰系统IV类(良性)组织病理学评价,16例为良性15例,恶性1例。4例归为Milan系统第六类,4例均为恶性,均行组织病理学评价。结论:目前的研究证实了细针穿刺细胞学是一种经济有效且无创的方法,可用于区分唾液腺的良性和恶性病变,这对于确定患者的下一个疗程至关重要。
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引用次数: 0
A comparative study of fluticasone propionate, mometasone furoate, and saline nasal spray in the treatment of children with adenoid hypertrophy} 丙酸氟替卡松、糠酸莫米松和生理盐水鼻喷雾剂治疗儿童腺样体肥大的比较研究
Pub Date : 2023-01-01 DOI: 10.4103/amit.amit_38_23
Gurbax Singh, P. Jolly, Sumit Prinja, A. S. Bawa, A. Vignesh
Introduction: Adenoidectomy is currently considered the treatment of choice for relief of the nasal airway obstruction due to adenoid hypertrophy. Evidence suggests that topical nasal steroid sprays can cause a reduction in adenoid size. We aim to compare the effectiveness of fluticasone propionate, mometasone furoate (MF) and saline nasal sprays in relieving the signs and symptoms of adenoid hypertrophy and in reducing the size of the adenoids. Materials and Methods: We conducted a randomized comparative study on 60 patients divided into three groups A, B, C (20 each). Group A patients treated with fluticasone propionate nasal spray (400 μg/day), Group B patients treated with MF nasal spray (100 μg/day), and Group C patients treated with saline spray (0.65% w/v in purified water which is made isotonic and buffered). Treatment was given up to 12 weeks with follow-up at 4, 8, and 12 weeks and at each follow-up visit assessment was done. Final data were analyzed using SPSS software version 21 and numerical variables associated with different groups were analyzed and analysis of variance test was used. Results: Diagnostic nasal endoscopy and X-ray grades at day 1 among the study groups were not statistically significant, whereas, at 12 weeks results among fluticasone and mometasone groups were significantly better (P < 0.001) as compared to the saline group. There was a significant improvement in the symptoms under all the categories with the use of fluticasone and mometasone. Conclusion: In our study, both fluticasone propionate and MF were able to effectively reduce symptoms and signs of adenoid hypertrophy as well as help in reducing the size of the enlarged adenoid. Both these drugs were well tolerated by the patients.
简介:腺样体切除术目前被认为是缓解由腺样体肥大引起的鼻气道阻塞的首选治疗方法。有证据表明,局部鼻腔类固醇喷雾剂可导致腺样体大小减小。我们的目的是比较丙酸氟替卡松、糠酸莫米松(MF)和生理盐水鼻喷雾剂在缓解腺样体肥大的体征和症状以及缩小腺样体大小方面的有效性。材料与方法:将60例患者随机分为a、B、C三组(各20例)进行比较研究。A组患者给予丙酸氟替卡松鼻喷雾剂(400 μg/d), B组患者给予MF鼻喷雾剂(100 μg/d), C组患者给予生理盐水喷雾(0.65% w/v的纯净水等渗缓冲)。治疗时间长达12周,随访时间为4周、8周和12周,每次随访时进行评估。最终数据采用SPSS软件21版进行分析,对不同组间的相关数值变量进行分析,并采用方差分析检验。结果:研究组第1天的诊断性鼻内窥镜和x线评分无统计学意义,而在12周时,氟替卡松组和莫米松组的结果明显优于生理盐水组(P < 0.001)。使用氟替卡松和莫米松后,所有类别的症状均有显著改善。结论:在我们的研究中,丙酸氟替卡松和MF都能有效地减轻腺样体肥大的症状和体征,并有助于缩小肿大的腺样体的大小。患者对这两种药物的耐受性都很好。
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引用次数: 0
Guided imagery intervention for the treatment of tension-type headache associated with state-trait anxiety 引导意象干预治疗伴状态-特质焦虑的紧张性头痛
Pub Date : 2022-07-01 DOI: 10.4103/amit.amit_80_21
Kehksha
Introduction: Guided imagery (GI) is a mind–body intervention, in which individuals generate mental images of pleasant objects or events in their minds. These mental images produce positivity and alter the perception of headaches and other pain disorders. A review of literature suggests that GI is an effective psychological treatment for tension-type headache (TTH) and state-trait anxiety. Hence, the present study aimed to assess the efficacy of GI on TTH associated with state-trait anxiety and to compare its efficacy with treatment as usual (TAU). Materials and Methods: Forty treatment-naïve patients diagnosed with TTH were selected from the psychiatry outpatient department through purposive sampling method. The Henry Ford Hospital Headache Disability Inventory and the State-Trait Anxiety Inventory for Adults were administered on all the patients for baseline data. Experimental group (n = 20) were given eight sessions of GI along with TAU for 2 months, whereas waitlist group (n = 20) were given only TAU. Results: A Significant positive association was obtained between emotional and functional disability of headache and state-trait anxiety at baseline. Postassessment findings demonstrated a significant reduction in severity and frequency of TTH, emotional and functional disability, and state-trait anxiety in the experimental group receiving GI as compared to the waitlist group. Conclusion: Patients living with TTH more commonly suffer from state-trait anxiety. Those patients who were given GI along with TAU for 2 months improved on severity and frequency of TTH, emotional and functional disability of TTH, and state-trait anxiety more effectively than those patients receiving only TAU. Consequently, it can be said that GI is an effective treatment for TTH and state-trait anxiety as compared to TAU.
导读:引导意象(GI)是一种身心干预,个体在其脑海中产生令人愉快的物体或事件的心理图像。这些心理图像产生积极情绪,改变对头痛和其他疼痛障碍的感知。文献综述表明,胃肠道是一种有效的心理治疗紧张性头痛(TTH)和状态-特质焦虑。因此,本研究旨在评估GI对与状态-特质焦虑相关的TTH的疗效,并将其与常规治疗(TAU)的疗效进行比较。材料与方法:采用目的抽样方法,选取精神科门诊诊断为TTH的treatment-naïve患者40例。对所有患者进行亨利福特医院头痛残疾量表和成人状态-特质焦虑量表作为基线数据。试验组(n = 20)给予8次GI治疗并给予TAU治疗2个月,而等候组(n = 20)只给予TAU治疗。结果:基线时头痛的情绪和功能失能与状态-特质焦虑呈显著正相关。后评估结果显示,与等候名单组相比,实验组接受GI治疗的TTH、情绪和功能残疾以及状态-特质焦虑的严重程度和频率显著降低。结论:TTH患者多存在状态-特质焦虑。与仅接受TAU治疗的患者相比,接受GI和TAU治疗2个月的患者在TTH的严重程度和频率、TTH的情绪和功能障碍以及状态-特质焦虑方面的改善更为有效。因此,与TAU相比,GI是治疗TTH和状态-特质焦虑的有效方法。
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引用次数: 0
Histomorphological analysis of gestational trophoblastic disease spectrum with clinicopathological correlation at a teaching hospital 某教学医院妊娠滋养细胞疾病谱与临床病理相关性的组织形态学分析
Pub Date : 2022-07-01 DOI: 10.4103/amit.amit_84_22
B. Soumya, D. Rajalakshmi, S. Kulkarni, R. Devi, V. Kulkarni
Introduction: Clinically, all trophoblastic lesions are frequently combined under a broad spectrum of gestational trophoblastic diseases (GTDs) without the use of specific pathological terms. However, studies now demonstrate that various forms of GTDs demonstrate differences in etiology, histogenesis, morphology, and clinical behavior. Thus, the need for diagnostic histopathology of these lesions to distinguish gestational trophoblastic neoplasms from nonneoplastic lesions and molar pregnancies and also for early anticipation for early anticipation, risk category stratification, prognostication, management, and prediction of persistent GTD. Our study aimed to study the histomorphological patterns of various types of GTD with light microscopy and the pattern of occurrence of GTDs in relation to age, parity, and gestation. Materials and Methods: The present study was conducted in the department of pathology, from January 2020 to April 2022. All GTDs confirmed by histopathological examination by hematoxylin- and eosin-stained slides were included. Results: The spectrum of GTDs found in this study was seventy cases of hydatidiform mole (92.10%), three cases of exaggerated placental site (EPS) reaction (3.94%), and two cases of choriocarcinoma (2.63%) and one case (1.31%) of placental site trophoblastic tumor (PSTT). The most common presenting symptom was vaginal bleeding (93.42%). Conclusion: Hydatidiform mole forms the most common type of GTD with an incidence of complete moles more than partial moles. Histomorphological examination and analysis are helpful for confirmatory diagnosis. The most common clinical presentation of GTD was vaginal bleeding followed by amenorrhea. Emphasis on detailed descriptive morphological assessment can help in the histological distinction of benign lesions such as EPS reaction and placental site nodule and avert such cases from being erroneously diagnosed as neoplastic. The Ki-67 proliferation index helped in distinguishing the EPS reaction from neoplastic lesions such as PSTT which requires surgical intervention and chemotherapy.
在临床上,所有滋养层病变经常合并在妊娠滋养层疾病(gtd)的广谱下,而不使用特定的病理术语。然而,目前的研究表明,各种形式的gtd在病因、组织发生、形态和临床行为上存在差异。因此,有必要对这些病变进行组织病理学诊断,以区分妊娠滋养细胞肿瘤与非肿瘤性病变和磨牙妊娠,并对早期预测、风险分类分层、预后、管理和持续性GTD的预测进行早期预测。我们的研究目的是在光镜下研究不同类型GTD的组织形态学模式,以及GTD的发生模式与年龄、胎次和妊娠期的关系。材料与方法:本研究于2020年1月至2022年4月在病理科进行。所有经苏木精和伊红染色切片组织病理学检查证实的gtd均被纳入。结果:本研究中发现的GTDs谱为葡萄胎70例(92.10%),胎盘部位过度反应3例(3.94%),绒毛膜癌2例(2.63%),胎盘部位滋养细胞瘤1例(1.31%)。最常见的临床表现为阴道出血(93.42%)。结论:葡萄胎是GTD最常见的类型,完全葡萄胎的发生率高于部分葡萄胎。组织形态学检查和分析有助于确诊。GTD最常见的临床表现是阴道出血,其次是闭经。强调详细的描述性形态学评估有助于组织学区分EPS反应和胎盘结节等良性病变,避免误诊为肿瘤。Ki-67增殖指数有助于区分EPS反应与肿瘤病变,如PSTT,需要手术干预和化疗。
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引用次数: 0
Workplace violence as a predictor of work-related stress among doctors 工作场所暴力是医生工作压力的预测因素
Pub Date : 2022-07-01 DOI: 10.4103/amit.amit_27_22
Adwitiya Das, M. Datta, S. Banerjee, Soumitra Mondal
Introduction: Workplace violence (WPV) toward health-care workers is increasing. The present study aims to estimate the proportion of resident doctors and interns of a tertiary care hospital who experienced WPV, to find out the perpetrators of WPV, and to ascertain any association between WPV and work-related stress. Materials and Methods: This observational, institution-based, cross-sectional study included resident doctors and interns working in six different departments of a tertiary care hospital. Data collection was done using a predesigned, pretested semi-structured self-administered questionnaire adapted and validated from the "WPV in the health sector survey questionnaire" from WHO along with "Perceived occupational stress scale." Results: Out of 323 participants, 247 (76.47%) experienced some form of WPV, 138 (42.72%) experienced physical violence and 203 (62.85%) experienced psychological violence. Patient relatives were reported as the only perpetrators of physical violence, while seniors of the study subjects were reported as main perpetrators of psychological violence. One hundred and thirty-four (42%) individuals reported work-related stress. On multivariate analysis, psychological violence was significantly associated with work-related stress. Conclusion: WPV was experienced by a high proportion of study subjects. Psychological violence was more frequently experienced, and senior colleagues were deemed responsible in most cases. WPV may be associated with work-related stress.
针对卫生保健工作者的工作场所暴力(WPV)正在增加。本研究旨在评估某三级医院住院医师与实习医师经历过“工作压力”的比例,找出“工作压力”的行凶者,并确定“工作压力”与“工作压力”之间的关系。材料和方法:这项观察性的、以机构为基础的横断面研究包括在一家三级保健医院的六个不同部门工作的住院医生和实习生。数据收集使用预先设计、预先测试的半结构化自我管理问卷,根据世卫组织的“卫生部门WPV调查问卷”和“感知职业压力量表”进行调整和验证。结果:在323名参与者中,247人(76.47%)经历过某种形式的WPV, 138人(42.72%)经历过身体暴力,203人(62.85%)经历过心理暴力。据报道,患者亲属是身体暴力的唯一施暴者,而研究对象的老年人则是心理暴力的主要施暴者。134人(42%)报告了工作压力。在多变量分析中,心理暴力与工作压力显著相关。结论:高比例的研究对象经历过WPV。心理暴力更常见,在大多数情况下,资深同事被认为要对此负责。WPV可能与工作压力有关。
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引用次数: 0
Practical anatomy online learning among COVID-19 pandemic era: perceptions of 1st-year MBBS students COVID-19大流行时代的实用解剖学在线学习:MBBS一年级学生的看法
Pub Date : 2022-07-01 DOI: 10.4103/amit.amit_52_22
S. Philip, Ranjna Janagal, R. Garg, S. Mehra
Introduction: With the rise of the COVID-19 pandemic, digital learning has been implemented in medical colleges across India to continue the ongoing medical education. Anatomy is the basis of medical science and is best learned through offline classes that allow students to experience the texture of structures and handling of specimens. During this pandemic period, cadaveric dissection was not used to study anatomy. The aim of this study was to learn about students' attitudes regarding virtual teaching and learning in anatomy, as well as the problems they may confront. Materials and Methods: A descriptive cross-sectional study was conducted in the department of anatomy among the 50 1st-year MBBS students of All India Institute of Medical Sciences, Rajkot in April 2021. Google Forms were used to obtain informed consent from students. Prevalidated questionnaires were given online to the students and responses were noted and descriptive statistical data was derived from the analysis. Results: About 37 (74%) respondents found traditional classes are better than online teaching. Majority preferred to attend anatomy practicals offline with safety precautions. About 17 (34%) showed interest in prerecorded videos. About 35 (60%) students faced social isolation as an impact of online learning. Technical issues and distractions were the key problems faced while learning anatomy online. Conclusion: Prerecorded videos of the practicals are helpful in teaching anatomy practicals, and can be used in future to ensure an unbroken, continuous, and effective delivery of medical education.
导读:随着COVID-19大流行的兴起,印度各地的医学院已经实施了数字化学习,以继续进行正在进行的医学教育。解剖学是医学的基础,最好通过线下课程学习,让学生体验结构的质地和标本的处理。在这次大流行期间,没有使用尸体解剖来研究解剖学。本研究的目的是了解学生对解剖学虚拟教学的态度,以及他们可能遇到的问题。材料和方法:于2021年4月在解剖学系对拉杰科特全印度医学科学研究所50名11年级MBBS学生进行了描述性横断面研究。使用谷歌表格获得学生的知情同意。在线向学生发放预先验证的问卷,并记录回答,并从分析中获得描述性统计数据。结果:约37(74%)受访者认为传统课程比在线教学更好。大多数人更愿意参加离线的解剖学实习,并采取安全措施。约有17人(34%)对预先录制的视频感兴趣。约有35名(60%)学生因在线学习而面临社会孤立。技术问题和干扰是在线学习解剖学时面临的主要问题。结论:预先录制的实习视频对解剖学实习教学有一定的帮助,可为今后医学教学的不间断、连续、有效的开展提供保障。
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引用次数: 0
Prognostic factors in lung adenocarcinoma with brain metastasis 肺腺癌伴脑转移的预后因素分析
Pub Date : 2022-07-01 DOI: 10.4103/amit.amit_61_22
E. Karaman, Sema Yilmaz Rakici
Introduction: Brain metastasis (BM) is significantly seen in lung adenocarcinoma and adversely affects survival. We aimed to evaluate the factors affecting the prognosis in patients with BM diagnosed with lung adenocarcinoma. Materials and Methods: Patients with BM between 2012 and 2022 were reviewed retrospectively. Demographic characteristics of the patients, primary tumor characteristics, presence of mutation, BM number, localization, size, development time, and treatment characteristics were evaluated. Inflammatory indices at the time of BM were examined. The overall survival time was calculated. Results: About 92.9% of 113 patients were male, the median age was 62 years (54.5–68.5), and follow-up was 8 months (3–18). BM was detected at the time of diagnosis in 62 (54.9%) of the patients, whereas BM developed later in 51 (45.1%) patients. Systemic treatment was applied to 72.5% of the patients. Survival was lower in patients with BM at diagnosis (4 vs. 14 months, P < 0.001). Primary tumor maximum standardized uptake value level was higher on fluorodeoxyglucose-positron emission tomography-computed tomography at diagnosis in patients with late BM (P = 0.004). The development time of BM was 9 months (4–16), and the median survival was 8 months (6.2–9.8). There was no difference between tumor localization or inflammatory indices and the development of BM and prognosis. The presence of BM at diagnosis and lack of systemic treatment were found to be factors that independently reduced survival (P < 0.001, P = 0.007). Conclusion: The presence of BM at diagnosis significantly reduces survival. It has been observed that systemic treatments applied in addition to local treatments have a positive effect on the prognosis.
脑转移(BM)在肺腺癌中非常常见,并对生存产生不利影响。我们的目的是评估影响肺腺癌患者预后的因素。材料和方法:回顾性分析2012 - 2022年BM患者。评估患者的人口统计学特征、原发肿瘤特征、突变的存在、BM数量、定位、大小、发展时间和治疗特征。检查BM时的炎症指标。计算总生存时间。结果:113例患者中男性占92.9%,中位年龄62岁(54.5 ~ 68.5),随访8个月(3 ~ 18)。62例(54.9%)患者在诊断时检测到脑脊髓炎,而51例(45.1%)患者脑脊髓炎发展较晚。72.5%的患者接受了全身治疗。诊断时BM患者的生存率较低(4个月vs 14个月,P < 0.001)。晚期BM患者诊断时,氟脱氧葡萄糖-正电子发射断层扫描-计算机断层扫描的原发肿瘤最大标准化摄取值水平较高(P = 0.004)。BM的发展时间为9个月(4-16),中位生存期为8个月(6.2-9.8)。肿瘤定位及炎症指标与脑转移的发展及预后无差异。诊断时BM的存在和缺乏全身治疗被发现是独立降低生存率的因素(P < 0.001, P = 0.007)。结论:诊断时BM的存在显著降低了生存率。据观察,除局部治疗外,全身治疗对预后有积极影响。
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引用次数: 0
Perception and practices of COVID appropriate behavior: A cross-sectional study among adult populations in rural and urban West Bengal 对COVID适当行为的认知和实践:西孟加拉邦农村和城市成年人的横断面研究
Pub Date : 2022-07-01 DOI: 10.4103/amit.amit_23_22
Archita Bhattacharya, M. Das, Sangeeta Ghosh, A. Samanta
Introduction: Recent COVID-19 pandemic is an unprecedented public health problem worldwide. Knowledge about the disease and adoption of COVID Appropriate Behavior (CAB) are of utmost importance in combating the pandemic. The study was conducted to assess and compare the knowledge, attitude, and practice and to determine different misconceptions and wrong practices related to the disease among urban and rural populations. Materials and Methods: A community-based analytical study with cross-sectional design was conducted from January 2021 to March 2021 among 144 adult residents from urban and rural West Bengal. Multistage sampling was adopted and a predesigned, pretested, semistructured schedule was used for interviewing study subjects. Results: Urban people were significantly more knowledgeable and more appropriate in attitude and practice than rural people (P < 0.05). The mean knowledge and attitude scores of urban population were significantly higher than the rural population across age groups, gender, occupation, and education (P < 0.05), whereas mean practice score was significantly higher across gender and occupation in the urban population compared to the rural population (P < 0.05). Many cultural and indigenous practices such as drinking warm water, using mouth wash, using home remedies were more common in urban areas and consumption of homeopathy medicines, lighting candles, making sound with utensils, blowing conch shells, and worshipping corona were observed more in rural areas. Conclusions: Wide gap exists in knowledge, attitude, and practice between urban and rural population and there were many wrong perceptions and practices surrounding COVID-19 among both urban and rural population. Appropriate policy for improving knowledge, attitude, and CAB is the need of the hour.
最近的COVID-19大流行是全球前所未有的公共卫生问题。了解疾病和采取COVID - 19适当行为(CAB)对于抗击大流行至关重要。本研究旨在评估和比较城乡人群对该病的认识、态度和做法,并确定城乡人群对该病的不同误解和错误做法。材料和方法:2021年1月至2021年3月,在西孟加拉邦城市和农村的144名成年居民中进行了一项基于社区的横断面设计分析研究。采用多阶段抽样,采用预先设计、预先测试、半结构化的访谈计划对研究对象进行访谈。结果:城市人群的知识水平、态度和行为方式均显著高于农村人群(P < 0.05)。不同年龄、性别、职业、学历的城市人口知识、态度平均得分显著高于农村人口(P < 0.05),不同性别、职业的城市人口实践平均得分显著高于农村人口(P < 0.05)。许多文化和土著习俗,如饮用温水、使用漱口水、使用家庭疗法等,在城市地区更为常见,而使用顺势疗法药物、点燃蜡烛、用器皿发声、吹海螺壳和崇拜日冕等,在农村地区更为常见。结论:城乡人口在知识、态度和实践方面存在较大差距,城乡人口对新冠肺炎的错误认识和做法较多。改善知识、态度和CAB的适当政策是当前的需要。
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引用次数: 0
A comparative study on comprehension of informed consent before emergency and elective surgical operative procedures 急诊与择期外科手术前知情同意理解的比较研究
Pub Date : 2022-07-01 DOI: 10.4103/amit.amit_90_22
Soumitra Mondal, S. Bhattacharya, P. Jana, K. Mitra
introduction: A health-care beneficiary should comprehend different aspects of medical and surgical interventions before giving consent to perform those. There is no defined way to find out adequate patient comprehension as part of the decision-making procedure to give consent. This study was conducted to find out the disparity of comprehensiveness between emergency and elective surgical operative procedures both in terms of knowledge dissemination and knowledge comprehension. Materials and Methods: A cross-sectional comparative study was conducted at the General Surgery Department of Medical College, Kolkata, during September and October 2021. An interviewer-administered questionnaire was used on patients undergoing emergency and elective surgical procedures. The comprehension level of informed consent (IC) form was scored as 1, 2, and 3 and compared between two groups using an unpaired t-test and Mann–Whitney U-test. Result: Data collection was done from 39 patients for emergency operative procedures and 52 for elective surgical procedures. A composite comprehension score was calculated after adjusting for questions not asked while taking IC. The mean comprehension score for emergency procedures was 18.86 and for planned surgery, it was 20.14. Unpaired t-test showed significantly high mean comprehension for planned procedures than the emergency procedures (P = 0.007). Comprehension is significantly poorer in emergency conditions even after controlling for age and literacy denoting difficulty in decision-making in emergency scenarios. Conclusion: It is suggested that the procedure of consent taking should be more structured and interactive so that even in stressful conditions participant understand better about the procedures and take their own decision instead of relying blindly on doctors.
导言:保健受益人在同意进行医疗和手术干预之前,应了解这些干预措施的不同方面。目前还没有明确的方法来确定是否有足够的患者理解,作为给予同意的决策程序的一部分。本研究旨在了解急诊外科手术与选择性外科手术在知识传播和知识理解方面的综合性差异。材料和方法:于2021年9月至10月在加尔各答医学院普通外科进行了横断面比较研究。对接受急诊和择期外科手术的患者采用访谈者填写的问卷。对知情同意(IC)表格的理解水平评分为1、2和3,并使用非配对t检验和Mann-Whitney u检验在两组之间进行比较。结果:对39例急诊手术患者和52例择期手术患者进行了数据收集。在调整了IC时未问的问题后,计算出综合理解得分。急诊手术的平均理解得分为18.86,计划手术的平均理解得分为20.14。未配对t检验显示,计划手术的平均理解程度显著高于紧急手术(P = 0.007)。在紧急情况下,即使在控制了年龄和识字程度之后,理解能力也明显较差,这表明在紧急情况下决策困难。结论:建议同意程序应更加结构化和互动性,使参与者即使在压力条件下也能更好地了解程序并做出自己的决定,而不是盲目地依赖医生。
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引用次数: 0
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Acta Medica International
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