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Association of temporal bone pneumatization and dehiscence of facial nerve canal: A cadaveric study 颞骨气化与面神经管破裂的关系:一项尸体研究
Pub Date : 2021-07-01 DOI: 10.4103/amit.amit_119_21
H. Nafees, Dilshad Usmani, Sonika Sharma, Shraddha Jain
Introduction: Facial nerve runs an extensive and complicated course through the temporal bone. Integrity of this nerve is affected by the anatomy of temporal bone. Hence, in-depth knowledge of facial canal and its surrounding structures is of utmost importance to avoid any iatrogenic injury during surgery of the middle ear. Temporal bone pneumatization has a great influence on pathogenesis and prognosis of temporal bone diseases. Hence, this study was planned to observe the pneumatization status of the temporal bone and whether there is any association between pneumatization of temporal bone and dehiscence of facial canal. Materials and Methods: The present study was conducted on 30 formalin-fixed adult temporal bones. Dissection of temporal bone was done in the Anatomy Department, TMMC and RC, TMU, Moradabad. Various cells groups were observed in the temporal bones. Facial canal was exposed, and any dehiscence present was then noted. Results: Out of total temporal bones studied, 20 belongs to the right side and 10 of the left side. Pneumatization status of bones was observed by the assessment of different cells present in the bone. Out of 30 bones, 19 (63.3%) bones were well pneumatized, in which 14 bones were of right side and five were of left side. About 11 (36.6%) bones were poorly pneumatized. In which, six were of the right side and five of the left side. In this study, dehiscence of the facial canal was observed in 9 (30%) temporal bones in which eight bones were well pneumatized and one bone was nonpneumatized. In our study, 21 (70%) bones showed no or insignificant dehiscence. Fisher exact test and Spearman's correlation test were applied to observe any association between the two variables. Conclusion: No association exists in between pneumatization of temporal bone and dehiscent facial nerve canal.
面神经在颞骨中有一条广泛而复杂的路线。这条神经的完整性受到颞骨解剖的影响。因此,在中耳手术中,深入了解面耳管及其周围结构对于避免医源性损伤至关重要。颞骨气化对颞骨疾病的发病机制和预后有很大影响。因此,本研究拟观察颞骨的气化状态,以及颞骨气化与面管开裂是否存在关联。材料与方法:对30例经福尔马林固定的成人颞骨进行研究。颞骨解剖在TMMC解剖科和Moradabad TMU解剖科完成。颞骨内观察到不同的细胞群。暴露面部管,观察有无裂开。结果:所研究的颞骨中,右侧20块,左侧10块。通过评估骨中存在的不同细胞来观察骨的气化状态。30块骨中,通气良好的19块(63.3%),其中右侧骨14块,左侧骨5块。11例(36.6%)骨通气不良。其中6个是右侧的,5个是左侧的。在本研究中,9块(30%)颞骨出现面管开裂,其中8块骨充气性良好,1块骨未充气性。在我们的研究中,21块(70%)骨头没有或不明显裂开。采用Fisher精确检验和Spearman相关检验观察两个变量之间的相关性。结论:颞骨气化与面神经管开裂无相关性。
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引用次数: 0
Correlation of chest radiographic findings and coagulation abnormality with disease severity in COVID-19 positive patients COVID-19阳性患者胸片表现、凝血异常与病情严重程度的相关性
Pub Date : 2021-07-01 DOI: 10.4103/amit.amit_27_21
Yogender Aggarwal, A. Malhotra, Deepti Arora, S. Chandak, Ashutosh Kumar, V. Bhandari
Introduction: The pandemic of coronavirus disease 19 (COVID-19) has engulfed most of the world and has constrained already overburdened health care systems, especially in developing countries. There is an urgent need of a rapid investigation to assess disease severity in suspected patients and the baseline chest radiograph may serve as a triage tool. The aim is to correlate chest radiographic findings and coagulation abnormality with disease severity in COVID-19 positive patients. Materials and Methods: This was a retrospective observational study which comprised 100 reverse transcription-polymerase chain reaction positive COVID-19 cases which were clinically stratified into three groups based on clinical parameters. Baseline chest radiograph and serum D-dimer levels at the time of admission for all the patients were reviewed. A radiographic severity score (Radiographic Assessment of Lung Edema [RALE]) was determined for all four quadrants of both lungs. The scores of each quadrant were added to yield the final severity score. Results: Baseline chest radiograph was abnormal in 75% of patients, whereas 25% of patients had normal chest radiograph. Most frequent radiographic abnormality was ground-glass opacity (GGO) (n = 31, 41.3%) followed by lung consolidation (n = 19, 25.3%), while 7 patients (9.3%) had both GGO and consolidation. The most common pattern of disease distribution was bilateral 34 (57.7%) and peripheral in 58 (69%). The optimal cut-off RALE score for identifying symptomatic patients was ≥3 (area under the curve [AUC] 0.760) and for identifying severe cases was ≥7 (AUC 0.870). Similarly, the optimal cut-off D-Dimer value for identifying symptomatic patients was ≥567 ng/ml (AUC 0.836) and for diagnosing severe disease was ≥1200 ng/ml (AUC 0.99). Conclusions: Radiographic RALE score and elevated serum D-Dimer levels correlate strongly with disease severity in COVID-19 patients and can be utilized for early identification of high-risk cases which can ultimately reduce mortality and morbidity.
2019冠状病毒病(COVID-19)大流行席卷了世界大部分地区,并限制了本已不堪重负的卫生保健系统,特别是在发展中国家。迫切需要快速调查以评估疑似患者的疾病严重程度,基线胸片可作为分诊工具。目的是将COVID-19阳性患者的胸片表现和凝血异常与疾病严重程度联系起来。材料与方法:采用回顾性观察性研究,选取100例逆转录聚合酶链反应阳性的COVID-19病例,根据临床参数分为3组。回顾了所有患者入院时的基线胸片和血清d -二聚体水平。对两个肺的所有四个象限进行放射学严重性评分(肺水肿放射学评估[RALE])。将每个象限的评分相加,得出最终的严重程度评分。结果:75%的患者胸片基线异常,而25%的患者胸片正常。最常见的影像学异常为磨玻璃样混浊(GGO) (n = 31, 41.3%),其次为肺实变(n = 19, 25.3%),同时有GGO和实变的7例(9.3%)。最常见的疾病分布模式是双侧34例(57.7%)和周围58例(69%)。识别有症状患者的最佳临界值RALE评分≥3(曲线下面积[AUC] 0.760),识别重症患者的最佳临界值RALE评分≥7 (AUC 0.870)。同样,诊断有症状患者的最佳d -二聚体临界值≥567 ng/ml (AUC 0.836),诊断重症患者的最佳临界值≥1200 ng/ml (AUC 0.99)。结论:影像学RALE评分和血清d -二聚体水平升高与COVID-19患者病情严重程度密切相关,可用于早期识别高危病例,最终降低病死率和发病率。
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引用次数: 0
Inter-relationship between gaming addiction, emotional intelligence, and psychological well-being of playerunknown's battlegrounds and non-playerunknown's battlegrounds online mobile game players: A comparative cross-sectional study 《绝地求生》和《非绝地求生》在线手机游戏玩家的游戏成瘾、情商和心理健康之间的相互关系:一项比较横断面研究
Pub Date : 2021-07-01 DOI: 10.4103/amit.amit_84_21
Avnika Jain, Preeti Jain
Introduction: Recently, increasing trend in popularity of online gaming has been seen worldwide. Online games such as PlayerUnknown's Battlegrounds (PUBG) and first-person shooter (FPS) games top the popularity chart among young population. Problematic Internet gaming is also being increasingly reported. The aim of this study was to evaluate the inter-relationship between gaming addiction, emotional intelligence (EI), and psychological well-being in players of PUBG and non-PUBG online shooter mobile games. Materials and Methods: Sixty-four male students (18–22 years) who had played either PUBG or non-PUBG FPS games for ≥3 h/week during the previous 6 months were included. Addictive potential of PUBG (played by n = 33) was compared with that of non-PUBG games (played by n = 31) using Gaming Addiction Scale (GAS). Psychological health and EI were assessed using Depression, Anxiety, and Stress Scale 21 (DASS-21) and Trait Emotional Intelligence Questionnaire-Short Form, respectively. Results: The prevalence of gaming addiction and psychological morbidity was significantly higher in PUBG compared to non-PUBG players. EI was comparable in both the groups. Correlational analysis in PUBG players showed a positive association between GAS and anxiety subscale and a negative association between EI and the depression and anxiety subscales. In non-PUBG players, a positive association between GAS and depression subscale and a negative association between EI and the depression, stress, and total DASS-21 scores was observed. Conclusion: These results suggest that addictive online gaming behavior has detrimental effect on the psychological well-being of players. Furthermore, EI has a potential protective impact against psychological morbidity in these subjects. Future studies may be planned to explore the influence of interventional EI training on psychological health and addictive gaming behavior of online gamers.
近年来,网络游戏在世界范围内呈现出日益流行的趋势。PlayerUnknown的《绝地求生》(PUBG)和第一人称射击游戏(FPS)等网络游戏在年轻人中最受欢迎。有问题的网络游戏也被越来越多地报道。本研究的目的是评估《绝地求生》和非《绝地求生》在线射击手游玩家的游戏成瘾、情商和心理健康之间的相互关系。材料与方法:研究对象为64名18-22岁,在过去6个月内每周玩《绝地求生》或非《绝地求生》FPS游戏≥3小时的男性大学生。使用游戏成瘾量表(Gaming Addiction Scale, GAS)对玩过《绝地求生》(n = 33)和玩过非《绝地求生》(n = 31)的玩家的成瘾潜力进行比较。采用抑郁、焦虑和压力量表21 (DASS-21)和特质情绪智力问卷(简表)分别评估心理健康和情商。结果:《绝地求生》玩家的游戏成瘾率和心理发病率明显高于非《绝地求生》玩家。两组的EI具有可比性。对《绝地求生》玩家的相关分析显示,GAS与焦虑子量表呈正相关,EI与抑郁和焦虑子量表呈负相关。在非绝地求生玩家中,GAS与抑郁子量表呈正相关,而EI与抑郁、压力和DASS-21总分呈负相关。结论:成瘾性网络游戏行为对玩家心理健康有不利影响。此外,情商对这些受试者的心理疾病有潜在的保护作用。未来的研究可能会进一步探讨干预性EI训练对网络游戏玩家心理健康和游戏成瘾行为的影响。
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引用次数: 1
Cytological grading of prostate carcinoma: A comparative study with the international society of urologic pathology grading system 前列腺癌的细胞学分级:与国际泌尿系统病理分级系统的比较研究
Pub Date : 2021-07-01 DOI: 10.4103/amit.amit_148_21
C. Kala, Ashutosh Bajpai, S. Kala, L. Khan
Introduction: The Gleason grading system is one of the most powerful prognostic predictors of carcinoma prostate. In 2014, a newer grading system, the International Society of Urologic Pathology (ISUP) grading system was proposed. The present study is a retrospective study conducted to compare the cytological grading of prostate carcinoma with the newly proposed ISUP grading system for prostate carcinoma. Materials and Methods: The present study is a retrospective study that included 42 cases of carcinoma prostate. The clinical data of the cases, fine-needle aspiration cytology slides, and histological slides were retrieved and reviewed. The cases were regraded using the ISUP grading system for prostate carcinoma. Statistical analysis was done using the Statistical Package for the Social Sciences (SPSS). Data were statistically analyzed and Chi-square testing was used to compare the two grading systems. Results: A total of 42 cases were studied. The preoperative grade was assigned to the smears and 26.19% (11 cases) were categorized as grade 1, 40.47% (17 cases) as grade 2, and 33.3% (14 cases) as grade 3. Histological sections were also graded according to the ISUP/grade groups (GG) system and 26.19% (11 cases) were graded as GG 1, 33.3% (14 cases) as GG2, 19.04% (8 cases) as GG3, 16.67% (7 cases) as GG4, and 4.47% (2 cases) as GG5. Conclusion: In the present study, it was concluded that there is a direct concordance between the histologic grade as proposed in the ISUP grading system and the cytologic grade on FNA.
Gleason分级系统是前列腺癌最有效的预后预测指标之一。2014年,一个更新的分级系统——国际泌尿病理学会(ISUP)分级系统被提出。本研究是一项回顾性研究,旨在比较前列腺癌的细胞学分级与新提出的ISUP前列腺癌分级系统。材料与方法:对42例前列腺癌患者进行回顾性研究。我们检索并回顾了病例的临床资料、细针穿刺细胞学切片和组织学切片。使用ISUP前列腺癌分级系统对病例进行重新分级。使用社会科学统计软件包(SPSS)进行统计分析。对资料进行统计学分析,采用卡方检验比较两种分级制度。结果:共研究42例。术前对涂片进行分级,其中26.19%(11例)为1级,40.47%(17例)为2级,33.3%(14例)为3级。组织切片按ISUP/分级分组(GG)系统分级,分别有26.19%(11例)评分为gg1, 33.3%(14例)评分为GG2, 19.04%(8例)评分为GG3, 16.67%(7例)评分为GG4, 4.47%(2例)评分为GG5。结论:在本研究中,我们得出结论,ISUP分级系统中提出的组织学分级与FNA上的细胞学分级之间存在直接的一致性。
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引用次数: 1
The role of nursing professionals and challenges encountered in the effective containment of the ongoing COVID-19 pandemic 护理专业人员在有效遏制当前COVID-19大流行方面的作用和面临的挑战
Pub Date : 2021-07-01 DOI: 10.4103/amit.amit_10_21
S. Shrivastava, P. Shrivastava
The coronavirus disease-2019 (COVID-19) outbreak, which emerged in the form of a cluster of cases in a single city has spread around the globe at a rapid pace. The contribution of the nursing professionals in the effective containment of the ongoing pandemic has been immense. The purpose of the current review is to explore the role of nursing professionals in the effective containment of the ongoing COVID-19 pandemic. An extensive search of all materials related to the topic was carried out in the PubMed search engine and the World Health Organization website and a total of 19 articles were selected based on the suitability with the current review objectives. It will not come as a surprise that almost all the nations across the world were not well prepared to effectively respond to the outbreak and that was quite evident in terms of lacunae in planning, preparation, organization, and leadership. In fact, owing to the shortage of personal protective equipment, there was always a threat that any of the healthcare professionals would might become the next statistics in the ongoing pandemic. The issues encountered by the nursing professional were not simple and they essentially demand serious consideration to have a better response in the future. To conclude, the dynamics of life have changed and it is no longer the same. The nursing professionals displayed immense resilience and mental strength regardless of the workload and ethical dilemma. It is the need of the hour to support them and improve their quality of lives to sustain our battle against the ongoing pandemic.
以单个城市聚集性病例的形式出现的2019冠状病毒病(COVID-19)疫情已迅速在全球蔓延。护理专业人员在有效遏制目前的大流行病方面作出了巨大贡献。本综述的目的是探讨护理专业人员在有效遏制正在进行的COVID-19大流行中的作用。在PubMed搜索引擎和世界卫生组织网站上对与该主题相关的所有材料进行了广泛搜索,并根据与当前审查目标的适用性选择了总共19篇文章。世界上几乎所有国家都没有做好有效应对疫情的充分准备,这一点不足为奇,这在规划、准备、组织和领导方面的漏洞是相当明显的。事实上,由于个人防护装备的短缺,任何医护专业人员都有可能成为当前大流行的下一个统计数字。护理专业人员遇到的问题并不简单,它们本质上需要认真考虑,以便在未来做出更好的反应。总之,生活的动力已经改变了,它不再是一样的。不管工作量和道德困境,护理专业人员表现出巨大的弹性和精神力量。现在需要支持他们,提高他们的生活质量,以维持我们与当前大流行病的斗争。
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引用次数: 0
The impact of interaction with orphanage children on quality of life of elderly females residing in old-age homes in a South Indian District: A comparative study 与孤儿院儿童互动对居住在南印度地区养老院的老年妇女生活质量的影响:一项比较研究
Pub Date : 2021-07-01 DOI: 10.4103/amit.amit_165_21
D. Jeeragyal, S. Udayar, R. Annadani, Malatesh Undi
Introduction: Improving the quality of life (QOL) of the elderly has been one of the crucial challenges of public health with increasing life expectancy. The study was done to assess the impact on QOL and psychiatric morbidities among elderly females in old age homes (OAH) who had interaction with orphanage children. Materials and Methods: An analytical cross-sectional study was conducted among 105 elderly females who were residing in OAHs in Chittoor District, India, from Sep–Dec 2019. Data were collected using older people's QOL scale, Hamilton's Scales (HAM-A and HAM-D). Ethical approval was obtained from the Institutional Ethics Committee. Data were analyzed using the Statistical Package for the Social Sciences (SPSS), software version 20. Results: About 82.9% of elderly females in OAHs who were interacting with orphanage children had good QOL when compared to those who were not (8.6%). A significant difference was observed in domains scores for overall life, independent home and neighborhood, psychological and emotional well-being, and religion in the elderly who were interacting with orphanage children when compared to those who did not. Mean scores for depression and anxiety were significantly higher (P = 0.001) in those who were not interacting with the orphanage children (23.23, 43.74) than with interaction (13.46, 43.74). Conclusions: Overall QOL was better in elderly females who had interaction with orphanage children when compared to those who did not. Furthermore, psychiatric morbidities (depression and anxiety) were significantly higher in those who were not having interaction with orphanage children than those with interaction (P = 0.001).
随着预期寿命的延长,提高老年人的生活质量(QOL)已成为公共卫生面临的重大挑战之一。本研究旨在评估与孤儿院儿童互动的老年女性在养老院(OAH)的生活质量和精神疾病的影响。材料与方法:对2019年9月至12月在印度Chittoor地区OAHs居住的105名老年女性进行了分析性横断面研究。数据采用老年人生活质量量表、汉密尔顿量表(HAM-A和HAM-D)收集。获得了机构伦理委员会的伦理批准。数据分析使用社会科学统计软件包(SPSS),软件版本20。结果:与孤儿院儿童有互动的老年妇女生活质量为82.9%,与无互动的老年妇女生活质量为8.6%。与没有与孤儿院儿童互动的老年人相比,与孤儿院儿童互动的老年人在总体生活,独立家庭和社区,心理和情感健康以及宗教信仰方面的得分有显著差异。未与孤儿院儿童互动组的抑郁和焦虑平均得分(23.23,43.74)显著高于与孤儿院儿童互动组(13.46,43.74)(P = 0.001)。结论:与孤儿院儿童有互动的老年女性的总体生活质量优于与孤儿院儿童无互动的老年女性。此外,与孤儿院儿童没有互动的儿童的精神疾病发病率(抑郁和焦虑)显著高于与孤儿院儿童有互动的儿童(P = 0.001)。
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引用次数: 0
Effectiveness of standard hand hygiene procedure versus use of hand rub in reducing transient bacterial colony from hands of health professionals working in critical care units: Quasi-experimental study 标准手卫生程序与使用洗手液减少重症监护病房卫生专业人员手部瞬态菌落的有效性:准实验研究
Pub Date : 2021-07-01 DOI: 10.4103/amit.amit_16_21
Betcy Pappachan, Anil Sharma, Anil Patidar
Introduction: Hand sanitation is the key measure suggested to counteract and control the spread of pathogens within the hospital setup to safeguard the patients and health professionals from disease. The purpose of this research is to see the effect of two different hand hygiene measures (soap-water, hand rub) on the level of bacterial colony among healthcare personnel's hands. Materials and Methods: A total of 44 health care workers were equally divided into two groups using nonprobability convenient sampling technique from various critical care units and approach utilized was quasi-experimental design. Using Pretest posttest design 88 culture swabs were obtained from the hands of participants before and after handwashing with soap and water and hand rub respectively and sent to microbiology laboratory for further testing for the presence of transient bacterial colonies. Results: Paired t-test was used to compare between the two groups. It showed that the mean difference of hand rub group is greater than that of soap and water group (27.9 > 5.7). Paired t-test value is 2.3 and P = 0.028 (P < 0.05). Hence, it was considered statistically significant. Moreover, Fischer's exact test was used to find out the association between pre-interventional bacterial count with selected demographic variable (P > 0.05). Hence, it was considered statistically insignificant. Conclusions: Hand hygiene with hand rub is more effective than handwashing with soap and water in transient bacterial colony reduction from hands of health care personnel.
手部卫生是预防和控制病原体在医院内传播的关键措施,以保护患者和医务人员免受疾病的侵害。本研究的目的是观察两种不同的手部卫生措施(肥皂水、洗手液)对医护人员手部细菌菌落水平的影响。材料与方法:采用准实验设计方法,采用非概率方便抽样技术,将44名来自不同重症监护病房的医护人员平均分为两组。采用前测后测设计,分别从受试者用肥皂水和洗手液洗手前和洗手后的手上获得88个培养拭子,送往微生物实验室进一步检测瞬时菌落的存在。结果:两组间比较采用配对t检验。结果表明,洗手液组的平均差异大于肥皂和水组(27.9 > 5.7)。配对t检验值为2.3,P = 0.028 (P < 0.05)。因此,它被认为具有统计学意义。此外,采用Fischer精确检验,找出介入前细菌计数与选定人口学变量的相关性(P > 0.05)。因此,它被认为是统计上不显著的。结论:用洗手液洗手比用肥皂和水洗手更能有效地减少医务人员手部的瞬时菌落。
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引用次数: 0
Markers of myocardial dysfunction in neonates with sepsis of various gestational age 不同胎龄新生儿脓毒症心肌功能障碍的标志物
Pub Date : 2021-07-01 DOI: 10.4103/amit.amit_53_21
N. Kretsu, O. Koloskova, T. Bilous
Introduction: Nowadays, the issues of early diagnostics of cardiovascular disorders in neonates with sepsis with the use of up-to-date methods of examination that can be applied as screening methods with the aim to verify the possible development of cardiovascular dysfunction remain urgent. To study certain clinical-instrumental parameters and biochemical markers in neonates depending on the gestational age to improve the prognosis with neonatal sepsis (NS). Materials and Methods: To realize the objective, 57 neonates were under our observation with verified diagnosis “NS.” I Group (23 patients – 40.3%) included neonates with the term of gestation 37–42 weeks, II Group– 34 preterm neonates (59.7%) with gestational age under 36 weeks inclusive. The latter group was subdivided depending on the term of gestation into IIA subgroup including 21 preterm neonates with NS and the term of gestation 32–36 weeks, IIB-subgroup included 13 neonates born in the term under 32 weeks of gestation. Results: Term males were found to suffer from sepsis more often (odds ratio = 5.19). Delivery by cesarean section for preterm neonates increased reliably the risk of NS development compared with term neonates (OR = 2.7). It was found that the average values of LDH activity in the groups were not higher than normal parameters with a tendency to decrease as the duration of pregnancy decreased. At the same time, in almost all examined patients, there was an excess of serum activity of Creatine phosphokinase-MB fraction (CPK-MB) (86.96% of cases in Group I and in 91.18% of cases in Group II) and in some patients an increase in serum aspartate aminotransferase (ACT) activity in 52.17% of patients with Group I, in 47.06% of cases from Group II, P > 0.05). The correlation analysis conducted showed that in preterm neonates suffering from NS increase of the myocardial functional ability of the left ventricle was associated with females and the number of days of inotropic support. Conclusions: Analysis of clinical-anamnestic findings determined that term males suffer from NS reliably more frequent which is clearly associated with the risk of NS development. Increase of CPK-MB serum activity can be considered as a sign of myocardial dysfunction development caused by NS. The analysis of echocardiographic parameters conducted in the group or preterm neonates found a direct correlation of the ejection fraction with initiation of cardiovascular resuscitation immediately after birth and the period of introduction of inotropic drugs.
导论:如今,使用最新的检查方法对新生儿败血症的心血管疾病进行早期诊断的问题仍然迫切,这些检查方法可以作为筛查方法,目的是验证心血管功能障碍的可能发展。探讨不同胎龄新生儿临床仪器参数及生化指标对改善新生儿脓毒症(NS)预后的影响。材料与方法:为达到目的,对确诊为“NS”的新生儿57例进行观察。I组23例(40.3%)为妊娠期37 ~ 42周的新生儿,II组34例(59.7%)为胎龄未满36周的早产儿。后一组根据妊娠期分为IIA亚组,包括21例妊娠期32 - 36周的NS早产儿,iib亚组包括13例妊娠期32周以下的新生儿。结果:足月男性败血症发生率较高(优势比为5.19)。与足月新生儿相比,早产新生儿剖宫产确实增加了NS发展的风险(OR = 2.7)。结果发现,各组LDH活性平均值均不高于正常参数,且随妊娠时间的缩短有降低的趋势。同时,在几乎所有检查的患者中,血清肌酸磷酸激酶- mb组分(CPK-MB)活性升高(I组为86.96%,II组为91.18%),部分患者血清天冬氨酸转氨酶(ACT)活性升高(I组为52.17%,II组为47.06%,P > 0.05)。相关性分析显示,患有NS的早产儿左心室心肌功能能力的增加与女性和肌力支持天数有关。结论:对临床记忆结果的分析表明,足月男性患NS的频率更高,这与NS发展的风险明显相关。血清CPK-MB活性升高可视为NS所致心肌功能障碍发展的标志。早产儿组超声心动图参数分析发现,射血分数与出生后立即启动心血管复苏和引入肌力药物的时间直接相关。
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引用次数: 0
Perceived stress, hardship, and self-reported health status of persons living with diabetes mellitus during Coronavirus Disease-19 pandemic and lockdown: A descriptive study 冠状病毒病-19大流行和封锁期间糖尿病患者的感知压力、困难和自我报告的健康状况:一项描述性研究
Pub Date : 2021-07-01 DOI: 10.4103/amit.amit_111_21
Masuma Yasmin, G. Bhattacharyya, Sujoy Ghosh, Kajari Bandyopadhyay, D. Mukhopadhyay, A. Biswas
Introduction: Coronavirus disease-19 (COVID-19) pandemic and subsequent complete lockdown have resulted in a lot of difficulties in availing essential services including medical care, especially among the persons living with Type 2 diabetes mellitus (DM). The situation was complicated by stress and fear due to unknown nature of the pandemic during initial phases. This study aimed at measuring the perceived stress and hardship faced by persons living with DM and assessing their health status during COVID-19 pandemic and lockdown in a tertiary care hospital in West Bengal. Materials and Methods: An institution-based, cross-sectional, descriptive study was conducted among diagnosed cases of Type 2 DM attending diabetic clinic outpatient department using an interview technique with the help of a predesigned pretested questionnaire that consisted of variables such as perpetual and experiential stress, hardship, and selected self-reported health parameters. Results: Out of a total of 304 study participants, majority responded positively regarding the items of perpetual and experiential stress. However, 80.8% of participants reported the reduction of income, and about 75% of them faced hardship of various extent to manage medicine and diet with low income. Only 9.1% of participants used teleconsultation as a sole method for health checkups. About one-third of participants considered their mental health status as poor or very poor, whereas two-third considered their physical health as good or excellent. Conclusion: Although our study participants did not have much stress or deterioration of health during lockdown, their income and regular care were affected to a certain extent. This emphasizes the need for context-specific measures.
导言:冠状病毒病-19 (COVID-19)大流行和随后的全面封锁导致在获得包括医疗在内的基本服务方面遇到了很多困难,特别是在2型糖尿病患者中。由于疫情的未知性质,初期阶段的紧张和恐惧使局势复杂化。本研究旨在测量糖尿病患者所面临的感知压力和困难,并评估他们在西孟加拉邦一家三级医疗医院COVID-19大流行和封锁期间的健康状况。材料和方法:对就诊于糖尿病门诊的2型糖尿病确诊病例进行了一项基于机构的、横断面的描述性研究,采用访谈技术,使用预先设计的预测问卷,该问卷由诸如永久性和体验性压力、困难和选定的自我报告健康参数等变量组成。结果:在304名研究参与者中,大多数人对永久性和体验性压力项目的反应是积极的。然而,80.8%的参与者表示收入减少,约75%的参与者在低收入的情况下面临不同程度的医疗和饮食困难。只有9.1%的参与者将远程咨询作为健康检查的唯一方法。大约三分之一的参与者认为自己的心理健康状况很差或很差,而三分之二的人认为自己的身体健康状况良好或非常好。结论:虽然我们的研究对象在封锁期间没有太多的压力或健康恶化,但他们的收入和日常护理在一定程度上受到影响。这强调需要针对具体情况采取措施。
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引用次数: 0
Symptomatology and outcome of acute COVID-19 illness in children at Faridabad, India 印度法里达巴德儿童急性COVID-19疾病的症状学和转归
Pub Date : 2021-07-01 DOI: 10.4103/amit.amit_138_21
Priyanka Gupta, O. Bhinder, V. Gupta, A. Ahuja, Anil R Pandey, R. M. Mandal Ravi
Introduction: The surveillance case definitions for coronavirus disease 2019 (COVID-19) in children adapted from adult guidelines emphasized the presence of fever and/or respiratory symptoms as the criteria for suspicion and testing. The clinical course of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in Indian children is still not well described. Materials and Methods: This observational study was done at a dedicated COVID-19 tertiary care hospital of Haryana, India, between April 1, 2020 and December 31, 2020, with due approval of Institutional Ethics Committee. A total of 86 SARS-CoV-2 positive inpatient children in the age group of 1 month − 12 years were enrolled to outline the clinical course and outcome of acute illness longitudinally over initial 2 weeks of infection. Clinical management and hospital discharge policy was guided by public health authorities and prevailing scientific evidence which were updated and notified time to time as the pandemic evolved. Descriptive statistics were applied to analyze the study variables. Results: Majority children (48/86; 56%) remained asymptomatic throughout 2-week surveillance period, 35 (41%) suffered mild, 2 (2%) moderate, and 1 (1%) severe disease. All children had intact survival. Comorbid condition(s) were present in five (6%) children. Among infants and the subset of children with premorbid condition(s), the proportion of children suffering symptomatic illness (88% and 80%, respectively) and moderate-severe illness (25% and 40%, respectively) was quite high. Respiratory symptoms (68%) and fever (50%) were the most common symptoms. Gastrointestinal symptoms were present in 26% symptomatic children. Fever was the only symptom in 11% children; and 16% children had only gastrointestinal symptoms without any fever or respiratory symptom(s). Conclusion: Acute SARS-CoV-2 infection in children is commonly asymptomatic, or a mild illness with not only respiratory but also non-respiratory manifestations. Thus, a high index of suspicion for SARS-CoV-2 infection is required by the treating physicians in this subgroup of population as they might play an important role in virus transmission and amplification. In case the testing is deferred among asymptomatic contacts or children with mild symptoms, they may be presumed SARS-CoV-2 infected, isolated, and managed accordingly.
导论:根据成人指南改编的2019年儿童冠状病毒病(COVID-19)监测病例定义强调,出现发烧和/或呼吸道症状是怀疑和检测的标准。印度儿童感染严重急性呼吸综合征冠状病毒-2 (SARS-CoV-2)的临床过程仍未得到很好的描述。材料和方法:本观察性研究于2020年4月1日至2020年12月31日在印度哈里亚纳邦一家专门的COVID-19三级护理医院进行,并得到了机构伦理委员会的适当批准。共有86名年龄在1个月至12岁的SARS-CoV-2阳性住院儿童入选,以概述感染最初2周内急性疾病的临床过程和结果。临床管理和出院政策以公共卫生当局和流行的科学证据为指导,这些证据随着大流行的演变而不断更新和通报。采用描述性统计对研究变量进行分析。结果:大多数儿童(48/86;56%)在2周的监测期间无症状,35人(41%)患有轻度疾病,2人(2%)患有中度疾病,1人(1%)患有重度疾病。所有儿童均完整存活。5名(6%)儿童存在合并症。在婴儿和有病前状况的儿童亚群中,患有症状性疾病的儿童比例(分别为88%和80%)和中重度疾病的儿童比例(分别为25%和40%)相当高。呼吸道症状(68%)和发烧(50%)是最常见的症状。26%有症状的儿童出现胃肠道症状。发烧是11%儿童的唯一症状;16%的儿童只有胃肠道症状,没有任何发烧或呼吸道症状。结论:儿童急性SARS-CoV-2感染通常无症状,或为轻症,既有呼吸道表现,也有非呼吸道表现。因此,治疗该亚组人群的医生需要高度怀疑SARS-CoV-2感染,因为他们可能在病毒传播和扩增中发挥重要作用。无症状接触者或症状较轻的儿童如果推迟检测,可推定其感染新冠病毒,并进行隔离处理。
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Acta Medica International
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