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Is Melioidosis a One Health-Neglected Disease in Iran? Melioidosis是伊朗一种被忽视的健康疾病吗?
Pub Date : 2020-07-25 DOI: 10.34172/ijtmgh.2020.16
Z. Baradaran-Seyed
According to the several scientific resources, Iran is considered to be among the melioidosis-endemic regions of the world; this is in stark contrast to the domestic stance in Iran, where the risk of melioidosis is speculated only as an emerging infectious disease in a non-endemic area. Recently, we have had devastating flash floods in the most provinces of Iran; the changing of soil structure may facilitate the cultivation of bacteria in the upper layers of the ground, consequently causes exposure and re-emergence of the disease. Considering previous isolation and identification of Burkholderia mallei, Burkholderia Pseudomallei, and Burkholderia cepacia complex from human, animal, and environment samples in Iran, it is urgently necessary to upgrade and equip infrastructures to identify and distinguish between pathogenic Burkholderia and commensals in the context of the One Health surveillance system. In the present perspective, the history of melioidosis in the country is presented to attract attention to the negligence of disease over the last four decades.
根据一些科学资源,伊朗被认为是世界上类鼻疽的流行地区之一;这与伊朗国内的立场形成了鲜明对比,在伊朗,类鼻疽的风险仅被推测为非流行地区的一种新发传染病。最近,我们在伊朗大多数省份发生了毁灭性的山洪暴发;土壤结构的变化可能有利于细菌在地面上层的培养,从而导致疾病的暴露和重新出现。考虑到之前在伊朗从人类、动物和环境样本中分离和鉴定出的锤状伯克霍尔德氏菌、假锤状伯克哈尔德菌和洋葱伯克霍尔德菌复合体,迫切需要升级和装备基础设施,以便在“一个健康”监测系统的背景下识别和区分致病性伯克霍尔德病和常见病。从目前的角度来看,介绍该国类鼻疽的历史,以引起人们对过去四十年来疾病疏忽的关注。
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引用次数: 0
Pathogenesis of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Respiratory Infection 严重急性呼吸综合征冠状病毒-2呼吸道感染的发病机制
Pub Date : 2020-07-25 DOI: 10.34172/IJTMGH.2020.24
A. S. Olagunju, I. Oladapo, S. O. Kosemani, F. Olorunfemi, Adesewa Sukurat Adeyemo
With the occurrence of a mysterious pneumonia in the Hubei province (Wuhan) of China in December 2019, a different coronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has commanded global awareness and has been named by the World Health Organization (WHO) as a public health emergency of international concern. Two other coronavirus infections (SARS and MERS) were also characterized by severe respiratory distress in 2002-2003. In addition to the new coronavirus, the emerging infectious diseases resulting in universal spread are caused by the β-coronavirus strains. Even though coronaviruses typically target the upper and/or lower respiratory tract, viral shedding into the plasma or serum is frequent, and the human coronavirus (CoV) represents 15%–30% of respiratory syndromes, including common colds. Based on a recent hypothesis, SARS-CoV-2 has been shown to induce lung injury by inhibiting the angiotensin converting enzyme-2 (ACE-2) and could possibly attack organs with high expression. With the lack of a vaccine or major treatment for the disease, palliative care is provided for individuals already infected with the virus. The aim of this review is to discuss the influence and relationship of the coronavirus, particularly SARS-CoV-2, on the respiratory system with a proposed mechanism of action in lung injury and pathogenesis.
随着2019年12月中国湖北省(武汉)发生神秘肺炎,另一种冠状病毒——严重急性呼吸系统综合征冠状病毒2型(SARS-CoV-2)引起了全球关注,并被世界卫生组织(世卫组织)命名为国际关注的突发公共卫生事件。2002-2003年,另外两种冠状病毒感染(SARS和中东呼吸综合征)也以严重呼吸窘迫为特征。除新型冠状病毒外,导致普遍传播的新发传染病都是由β冠状病毒株引起的。尽管冠状病毒通常以上呼吸道和/或下呼吸道为目标,但病毒经常进入血浆或血清,人类冠状病毒(CoV)占呼吸道综合征(包括普通感冒)的15%-30%。根据最近的假设,SARS-CoV-2已被证明通过抑制血管紧张素转换酶-2 (ACE-2)诱导肺损伤,并可能攻击高表达的器官。由于缺乏针对该疾病的疫苗或主要治疗方法,只能为已经感染该病毒的个人提供姑息治疗。本文的目的是讨论冠状病毒,特别是SARS-CoV-2对呼吸系统的影响和关系,并提出肺损伤的作用机制和发病机制。
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引用次数: 4
Fear and Panic of COVID-19 对COVID-19的恐惧和恐慌
Pub Date : 2020-07-14 DOI: 10.34172/ijtmgh.2020.15
S. Saadat, M. Izadi, N. J. Jafari, H. Abolghasemi, Saeedreza Jamalimoghadamsiyahkali, A. Jamalian, S. Fathi, B. Einollahi, A. Ghazale, Ramezan Jafari, M. Mesri, M. Ebrahimi, M. Asadi, A. Ghadian, Z. Rostami, E. Nemati, H. Nikoueinejad, Bentolhoda Beyram, Seyed Mohammad Hossein Tabatabaei, S. Imanizadeh, Milad Nafari, M. Javanbakht
media war in which “fear” is highlighted rather than discussions about the coronavirus disease 2019 (COVID-19). Despite all the current data, little is known about the real figures of COVID-19, and ignorance breeds fear all over the world, particularly in Iran. While media images are rapidly circulating and COVID-19 has become propaganda in many regions due to coronavirus rumors, one fear is in the public mind about mortality rates reported elsewhere.1,2 In the face of emergencies, a more interdisciplinary and cross-sectorial approach is of great importance for curtailing COVID-19 outbreak, which would, in turn, lead to a minimization of the damage. Transparency in reports and actions is also very important.3 The concept of health communication is of great importance. Now, in addition to trying to send scientific exchanges by traditional venues (e.g., journals and conferences), it must be explained to the public what really happened or is happening in public language (jargon and insider language) instead of scientific terminology, providing opportunities for engaging public audiences without customization. In other words, it is important to get a real perspective of the disease, such as initial estimates of epidemiological parameters, risk of acquiring infection, human-to-human transmission, and epidemic forecasts by considering what the public is hearing and practicing health communication. To a non-specialist, most specific terms in scientific language are not clear. Therefore, mass media can be targeted by representatives using a science communication approach and problem-based learning sessions, where a synergistic collaboration of multiple disciplines can be considered under the terms of One Health by human and animal health agencies, national organizations’ downstream sectors, and scientific societies to underpin public health awareness based on reliable information. Efforts at communicating information about infectious diseases should consider media outreach and community meetings. Moreover, an increased shift in special media sources in many parts of the world, including Internet use (e.g., websites), social media (e.g., Facebook, LinkedIn, Instagram, etc.), and Internet contacts can be of great importance for community engagement strategies based on infectious disease communication; other sources of health information, such as text alerts, artistic brochure design, and apps, are also easy strategies in this regard. Of course, the credibility of a source http://ijtmgh.com Int J Travel Med Glob Health. 2020 Aug;8(3):91-92 doi 10.34172/ijtmgh.2020.15 TMGH IInternational Journal of Travel Medicine and Global Health J
强调“恐惧”的媒体战争,而不是关于2019冠状病毒病(新冠肺炎)的讨论。尽管有目前的所有数据,但人们对新冠肺炎的真实数字知之甚少,无知在世界各地滋生恐惧,尤其是在伊朗。尽管媒体图片正在迅速传播,而且由于冠状病毒谣言,新冠肺炎已成为许多地区的宣传品,但公众对其他地方报道的死亡率感到担忧。1,2面对紧急情况,采取更跨学科和跨部门的方法对于遏制新冠肺炎疫情至关重要,而这反过来又会将损害降至最低。报告和行动的透明度也非常重要。3健康沟通的概念非常重要。现在,除了尝试通过传统的场所(如期刊和会议)进行科学交流外,还必须用公共语言(行话和内部语言)而不是科学术语向公众解释真正发生或正在发生的事情,为无需定制就吸引公众提供机会。换言之,重要的是要通过考虑公众所听到的和实践的健康传播,对疾病有一个真实的了解,例如对流行病学参数、感染风险、人传人和流行病预测的初步估计。对于非专业人士来说,科学语言中的大多数具体术语都不清楚。因此,代表们可以使用科学传播方法和基于问题的学习课程来瞄准大众媒体,在这些课程中,人类和动物卫生机构、国家组织的下游部门、,以及科学社会,以可靠的信息为基础加强公众健康意识。传播传染病信息的工作应考虑媒体外联和社区会议。此外,世界许多地区特殊媒体来源的日益转变,包括互联网使用(如网站)、社交媒体(如脸书、领英、Instagram等)和互联网联系人,对基于传染病传播的社区参与战略可能具有重要意义;其他健康信息来源,如文本提醒、艺术宣传册设计和应用程序,也是这方面的简单策略。当然,来源的可信度http://ijtmgh.comInt J Travel Med Glob Health。2020年8月;8(3):91-92 doi 10.34172/ijtmgh.2020.15 TMGH IIInternational Journal of Travel Medicine and Global Health J
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引用次数: 6
Using AHP to Prioritize Barriers in Developing Medical Tourism: Case of Turkey 运用层次分析法确定医疗旅游发展障碍:以土耳其为例
Pub Date : 2020-05-31 DOI: 10.34172/ijtmgh.2020.12
Doğancan Çavmak, Şeyda Çavmak
Introduction: In the globalizing world; the concept of medical tourism comes to the fore with the increase in travel freedoms between countries, easier transportation facilities, and the increased quality of healthcare services in different countries. This study aims to examine the barriers to developing medical tourism and prioritize the factors to give an insight on where to allocate resources in the scope of a conceptual framework on medical tourism. Methods: Barriers to medical tourism in Turkey were identified based on the literature and experts’ opinions. As a result of the expert opinions, 23 factors were identified and grouped under five main categories. The analytical hierarchy process method was used to prioritize the factors. A pair-wise comparison form was prepared by the researcher and sent to experts. The data obtained from these forms was analyzed and weights were calculated. Results: The factors were ranked from most important to least important as follows: negative corporate image (w=0.319), quality of healthcare (w=0.198), incompatible regulations/law (w=0.177), human resources (w=0.163), and underdeveloped infrastructure (w=0.142). Conclusion: It was determined that the development of medical tourism is not sufficient, despite the great potential of Turkey in terms of technological healthcare services and attractiveness of tourism destinations. Major attempts should be made in marketing to attract medical tourists.
引言:在全球化的世界;随着国家间旅行自由度的增加、交通设施的便利以及不同国家医疗服务质量的提高,医疗旅游的概念开始崭露头角。本研究旨在研究发展医疗旅游的障碍,并优先考虑因素,以便在医疗旅游概念框架的范围内深入了解在哪里分配资源。方法:根据文献资料和专家意见,确定土耳其医疗旅游的障碍。根据专家意见,确定了23个因素,并将其分为五大类。采用层次分析法对各因素进行排序。研究人员准备了一份成对比较表,并发给了专家。从这些表格中得到的数据进行了分析,并计算了权重。结果:企业形象不良(w=0.319)、卫生保健质量(w=0.198)、法规/法律不兼容(w=0.177)、人力资源(w=0.163)、基础设施不发达(w=0.142)是影响企业健康的最重要因素。结论:确定医疗旅游的发展是不够的,尽管土耳其在技术医疗保健服务和旅游目的地的吸引力方面有很大的潜力。应在市场营销方面作出重大努力,以吸引医疗游客。
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引用次数: 12
Factors Affecting Destination Choice in Medical Tourism 影响医疗旅游目的地选择的因素
Pub Date : 2020-05-31 DOI: 10.34172/ijtmgh.2020.13
Haşim Çapar, Ö. Aslan
Introduction: Although many factors can affect the choice of destination in medical tourism, some factors are indispensable to medical tourists and medical tourism. The aim of this study was to analyze important factors affecting the selection of a destination by potential medical tourists. Methods: This descriptive, cross-sectional study, conducted in Turkey, included a population of 1700 people and a sample size of 317 people selected through purposive sampling. Values were evaluated with a 95% confidence interval and 0.05 standard error. A value of P<0.05 was considered statistically significant. The medical tourism scale and a demographic information form were used in data collection. Exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and path analysis were used as statistical methods. Analyses were made using IBM SPSS-AMOS 25.0. Results: In this study, 56.5% of the participants were male and 43.5% were female. The factors affecting the selection of medical tourism destinations were determined to be, in order of importance, accessibility of health care service (X̄ = 4.68 ± 1.073), level of security and safety (X̄ = 4:57 ± 1.122), quality of health care service (X̄ = 4:39 ± 1.129), level of hygiene (X̄ = 4.16 ± 1.381), potential of savings-low cost (X̄ = 4.07 ± 1.447), and tourism opportunities (X̄ = 4.02 ± 1.540). Conclusion: It is thought that the current study will make a serious contribution to the field of medical tourism both in practice and in theory.
导读:虽然影响医疗旅游目的地选择的因素很多,但对于医疗旅游者和医疗旅游来说,有些因素是不可或缺的。本研究的目的是分析影响潜在医疗游客选择目的地的重要因素。方法:这项描述性横断面研究在土耳其进行,包括1700人的人口和317人的样本量,通过有目的抽样选择。值以95%置信区间和0.05标准误差进行评估。P<0.05为差异有统计学意义。数据收集采用医疗旅游量表和人口统计信息表。统计方法采用探索性因子分析(EFA)、验证性因子分析(CFA)和通径分析。使用IBM SPSS-AMOS 25.0进行分析。结果:研究对象中男性占56.5%,女性占43.5%。影响医疗旅游目的地选择的因素依次为:医疗服务可及性(X′= 4.68±1.073)、安全保障水平(X′= 4:57±1.122)、医疗服务质量(X′= 4:39±1.129)、卫生水平(X′= 4.16±1.381)、节约低成本潜力(X′= 4.07±1.447)、旅游机会(X′= 4.02±1.540)。结论:本文的研究将对医疗旅游领域的实践和理论做出重大贡献。
{"title":"Factors Affecting Destination Choice in Medical Tourism","authors":"Haşim Çapar, Ö. Aslan","doi":"10.34172/ijtmgh.2020.13","DOIUrl":"https://doi.org/10.34172/ijtmgh.2020.13","url":null,"abstract":"\u0000 Introduction: Although many factors can affect the choice of destination in medical tourism, some factors are indispensable to medical tourists and medical tourism. The aim of this study was to analyze important factors affecting the selection of a destination by potential medical tourists. Methods: This descriptive, cross-sectional study, conducted in Turkey, included a population of 1700 people and a sample size of 317 people selected through purposive sampling. Values were evaluated with a 95% confidence interval and 0.05 standard error. A value of P<0.05 was considered statistically significant. The medical tourism scale and a demographic information form were used in data collection. Exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and path analysis were used as statistical methods. Analyses were made using IBM SPSS-AMOS 25.0. Results: In this study, 56.5% of the participants were male and 43.5% were female. The factors affecting the selection of medical tourism destinations were determined to be, in order of importance, accessibility of health care service (X̄ = 4.68 ± 1.073), level of security and safety (X̄ = 4:57 ± 1.122), quality of health care service (X̄ = 4:39 ± 1.129), level of hygiene (X̄ = 4.16 ± 1.381), potential of savings-low cost (X̄ = 4.07 ± 1.447), and tourism opportunities (X̄ = 4.02 ± 1.540). Conclusion: It is thought that the current study will make a serious contribution to the field of medical tourism both in practice and in theory.","PeriodicalId":32539,"journal":{"name":"International Journal of Travel Medicine and Global Health","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41596117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
"I Was Scared I Might Die Alone": A Qualitative Study on the Physiological and Psychological Experience of COVID-19 Survivors and the Quality of Care Received at Health Facilities “我害怕我可能会孤独死去”:关于COVID-19幸存者的生理和心理体验以及卫生机构接受的护理质量的定性研究
Pub Date : 2020-05-27 DOI: 10.34172/ijtmgh.2020.09
I. Olufadewa, M. Adesina, B. Oladokun, A. Baru, R. Oladele, T. Iyanda, Oluwatosin Joseph Ajibade, Funmilayo Abudu
Introduction: Although several coronavirus disease 19 (COVID-19) studies have focused on the biomedical and epidemiological manifestations of the COVID-19 virus, there is a dearth of studies that have reported the experiences of COVID-19 survivors. This study investigated the physiological and psychological experiences of COVID-19 survivors and the quality of care that they received during their recovery processes. Methods: A phenomenological approach and a purposive sampling technique were employed to select eligible participants whose reported interviews/videos were published on reputable online media channels. The selection processes involved three researchers who had independently searched and assessed the interviews and their sources; for veracity, availability of vital information to meet the study objectives, and to ensure it followed the inclusion criteria. Video interviews were transcribed and data were analyzed using thematic analysis. Results: Thirty-nine participants (COVID-19 survivors) within the age range of 20-95 from over 15 countries and 5 continents were included in this study. Clinical symptoms commonly reported included feeling feverish, severe, persistent and dry cough, difficulty in breathing, cold, body pains, and aches. Many participants had negative mental health experiences such as being scared, anxious, guilty feelings, and worrying about their recovery. Few participants had positive mental health experiences such as the feeling of encouragement from family and trusted friends. Many participants were satisfied with the quality of care at health centers, though some experienced early difficulty in getting tested. Conclusion: There are psychological impacts associated with the SARS-CoV-2 infection. Psychological interventions should be included in the management of COVID-19 patients and survivors.
导语:虽然一些关于COVID-19的研究侧重于COVID-19病毒的生物医学和流行病学表现,但缺乏报道COVID-19幸存者经历的研究。本研究调查了COVID-19幸存者的生理和心理经历以及他们在康复过程中获得的护理质量。方法:采用现象学方法和有目的的抽样技术,选择符合条件的参与者,他们的采访/视频报告在知名的网络媒体渠道上发表。选择过程涉及三位研究人员,他们独立地搜索和评估访谈及其来源;对于准确性,重要信息的可用性,以满足研究目标,并确保它遵循纳入标准。录像采访被记录下来,数据使用专题分析进行分析。结果:本研究纳入了来自5大洲15个国家、年龄在20-95岁之间的39名参与者(COVID-19幸存者)。通常报告的临床症状包括发热、严重、持续干咳、呼吸困难、感冒、身体疼痛和疼痛。许多参与者都有负面的心理健康经历,比如害怕、焦虑、内疚和担心自己的康复。很少有参与者有积极的心理健康经历,比如来自家人和值得信赖的朋友的鼓励。许多参与者对医疗中心的护理质量感到满意,尽管有些人在早期检测时遇到了困难。结论:SARS-CoV-2感染存在心理影响。心理干预应纳入COVID-19患者和幸存者的管理。
{"title":"\"I Was Scared I Might Die Alone\": A Qualitative Study on the Physiological and Psychological Experience of COVID-19 Survivors and the Quality of Care Received at Health Facilities","authors":"I. Olufadewa, M. Adesina, B. Oladokun, A. Baru, R. Oladele, T. Iyanda, Oluwatosin Joseph Ajibade, Funmilayo Abudu","doi":"10.34172/ijtmgh.2020.09","DOIUrl":"https://doi.org/10.34172/ijtmgh.2020.09","url":null,"abstract":"Introduction: Although several coronavirus disease 19 (COVID-19) studies have focused on the biomedical and epidemiological manifestations of the COVID-19 virus, there is a dearth of studies that have reported the experiences of COVID-19 survivors. This study investigated the physiological and psychological experiences of COVID-19 survivors and the quality of care that they received during their recovery processes. Methods: A phenomenological approach and a purposive sampling technique were employed to select eligible participants whose reported interviews/videos were published on reputable online media channels. The selection processes involved three researchers who had independently searched and assessed the interviews and their sources; for veracity, availability of vital information to meet the study objectives, and to ensure it followed the inclusion criteria. Video interviews were transcribed and data were analyzed using thematic analysis. Results: Thirty-nine participants (COVID-19 survivors) within the age range of 20-95 from over 15 countries and 5 continents were included in this study. Clinical symptoms commonly reported included feeling feverish, severe, persistent and dry cough, difficulty in breathing, cold, body pains, and aches. Many participants had negative mental health experiences such as being scared, anxious, guilty feelings, and worrying about their recovery. Few participants had positive mental health experiences such as the feeling of encouragement from family and trusted friends. Many participants were satisfied with the quality of care at health centers, though some experienced early difficulty in getting tested. Conclusion: There are psychological impacts associated with the SARS-CoV-2 infection. Psychological interventions should be included in the management of COVID-19 patients and survivors.","PeriodicalId":32539,"journal":{"name":"International Journal of Travel Medicine and Global Health","volume":"8 1","pages":"51-57"},"PeriodicalIF":0.0,"publicationDate":"2020-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41938177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
Examination of Emergency Medicine Physicians’ and Residents’ Twitter Activities During the First Days of the COVID-19 Outbreak COVID-19疫情暴发初期急诊医师和居民推特活动调查
Pub Date : 2020-05-09 DOI: 10.34172/ijtmgh.2020.08
M. Boğan, M. Karadağ, Fatma Boğan
Introduction: Social media has become an important element of interaction and found itself a place in every aspect of our lives. This study examined the twitter activities of emergency medicine physicians and residents (EMP&R) about the COVID-19 outbreak. Methods: The study concentrated on Twitter, a major social media network. To identify accounts owned by EMP&R, followers of the official accounts of two emergency medicine physician associations in our country were reviewed. Results: In total, 251 accounts whose owners stated they were EMP&R in their biographies, were public, and had tweeted within the last year were identified. Among the 210 tweets posted about coronavirus, 42.4% contained comments and suggestions, 18.6% institutional announcements, 17.1% news, 14.8% scientific content, and 7.1% contained humor. Conclusion: This study examined the importance of Twitter posts during outbreaks and the attitudes of emergency medicine doctors on this issue. Based on the results, it is thought that EMP&R should share more.
简介:社交媒体已经成为互动的重要元素,并在我们生活的方方面面都占有一席之地。这项研究调查了急诊医生和住院医生(EMP/R)关于新冠肺炎疫情的推特活动。方法:研究集中在主要的社交媒体网络推特上。为了确定EMP&R拥有的账户,对我国两个急诊医师协会的官方账户的关注者进行了审查。结果:总共有251个账户的所有者在他们的传记中表示他们是EMP&R,这些账户是公开的,并且在去年发过推特。在发布的210条关于冠状病毒的推文中,42.4%包含评论和建议,18.6%包含机构公告,17.1%包含新闻,14.8%包含科学内容,7.1%包含幽默。结论:本研究考察了疫情期间推特帖子的重要性以及急诊医生对此问题的态度。基于这些结果,人们认为EMP和R应该分享更多。
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引用次数: 4
Awareness and Practice of Pre-travel Vaccination Among International Travelers Departing from Addis Ababa Bole International Airport 从亚的斯亚贝巴博莱国际机场出发的国际旅客旅行前接种疫苗的认识和做法
Pub Date : 2020-04-30 DOI: 10.34172/ijtmgh.2020.10
O. Jegede, A. Ali, W. Ayele
Introduction: International travelers are exposed to health risks and may transmit infections before, during, or after travel. Travelers are expected to take vaccinations prior to travel. The current study assessed the factors associated with the practice of pre-travel vaccination among travelers departing through Addis Ababa Bole International Airport after their stay in Ethiopia. Methods: This cross-sectional study was conducted among 670 international travelers. A multistage sampling technique was used to ensure the representativeness of travel destinations. Awareness and practice of pre-travel vaccination were assessed using a self-administered questionnaire distributed at the departure lounges of the airport. Logistic regression analysis was used to identify significant factors (at P < 0.05) associated with pre-travel vaccination status. Median age was reported with its interquartile range (IQR). Results: A total of 639 questionnaires were analyzed given a response rate of 95.4%. The median age of participants was 34 years (IQR 28-41). Five hundred and eighty travelers (90.8%) were aware of pre-travel vaccinations, 531 (83.1%) took vaccinations, and 185 (29.0%) had their vaccination cards checked upon arrival in Ethiopia. The vaccination rate of the three recommended vaccines for all travelers were yellow fever (72.5%); diphtheria, pertussis, and tetanus (DPT) (21.4%); and influenza (10.8%). Age, marital status, religion, and having vaccination cards checked on previous trips were associated with vaccination status at P values of 0.047, 0.035, <0.001, and 0.002, respectively. Conclusion: The uptake of recommended vaccinations for all travelers, especially DPT and influenza was low. It is pertinent for border health staff to scale up vaccination card inspection at points of entry.
导言:国际旅行者面临健康风险,并可能在旅行前、旅行中或旅行后传播感染。旅行者应在旅行前接种疫苗。目前的研究评估了在埃塞俄比亚停留后通过亚的斯亚贝巴博莱国际机场离境的旅行者在旅行前接种疫苗的相关因素。方法:对670名国际旅行者进行横断面研究。采用多阶段抽样技术,保证了旅游目的地的代表性。利用在机场候机室分发的自填问卷,评估了旅行前接种疫苗的认识和做法。采用Logistic回归分析确定与旅行前接种疫苗状况相关的显著因素(P < 0.05)。报告中位年龄及其四分位数范围(IQR)。结果:共分析问卷639份,回复率为95.4%。参与者的中位年龄为34岁(IQR 28-41)。580名旅行者(90.8%)知道旅行前接种疫苗,531名旅行者(83.1%)接种了疫苗,185名旅行者(29.0%)在抵达埃塞俄比亚时检查了疫苗接种卡。所有旅行者的3种推荐疫苗接种率均为黄热病(72.5%);白喉、百日咳和破伤风(DPT) (21.4%);流感(10.8%)。年龄、婚姻状况、宗教信仰和以前旅行中是否检查过疫苗接种卡与疫苗接种状况相关,P值分别为0.047、0.035、<0.001和0.002。结论:所有旅行者推荐接种疫苗,特别是百白破和流感疫苗的接种率较低。边境卫生人员应在入境口岸加强疫苗接种卡检查。
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引用次数: 2
Unravelling the Pathogenesis of Severe COVID-19 Pneumonia: Are There Possible Insights From High Altitude? 揭示重症新冠肺炎肺炎的发病机制:从高空有可能的见解吗?
Pub Date : 2020-04-30 DOI: 10.34172/ijtmgh.2020.14
G. Flaherty, P. Hession
The global pandemic of coronavirus disease 2019 (COVID-19) continues to exact a heavy toll on human lives, fragile healthcare systems and international travel. Following its initial rapid spread via international travel routes,1 sustained community transmission is now the major route of infection worldwide. High rates of severe pneumonia requiring prolonged ventilation, pre-symptomatic viral shedding and a disproportionate burden of mortality in older populations, are among the most challenging features of this novel coronavirus infection. A clearer profile of the clinical evolution of the disease is beginning to emerge. Gaps in our understanding of its pathogenesis compromise efforts to deliver targeted therapies to the most severely ill patients, however. The authors have, between them, managed critically ill patients with COVID-19 disease and high altitude pulmonary oedema (HAPE). Arguments have recently been advanced in the medical literature to suggest that COVID-19 lung injury may share a common pathophysiology with HAPE2 and, indeed, intriguing similarities do exist in their clinical presentation. Here we explore the points of comparison and contrast between these discrete conditions. HAPE was regarded historically by Andean residents as the “pneumonia of the mountains”.3 Symptoms of HAPE and COVID-19 overlap, with an initial dry cough, fever, dyspnoea and chest tightness. Also more common in males, severely affected HAPE patients are typically tachycardic, tachypnoeic and markedly hypoxaemic. Patchy nodular infiltrates on chest radiography and peripheral ground-glass opacities on CT imaging are features of both conditions, although they may also be observed in other respiratory diseases causing a noncardiogenic pulmonary oedema.4 Acute respiratory distress syndrome (ARDS) complicates the most severe cases of COVID-19 pneumonia and is also described in severe HAPE. The cytokine storm of the host inflammatory immune response to SARS-CoV-2 infection is central to the development of severe illness in a subset of patients, with the worst clinical outcomes reported in male patients, the elderly and in those with pre-existing illness. Anecdotally, adverse clinical outcomes are also observed more frequently in obese patients. High altitude travellers with a brisk hypoxic pulmonary vasoconstrictor response (HPVR) and risk factors for pulmonary hypertension, including obesityhypoventilation syndrome, may develop uneven pulmonary arteriolar vasoconstriction. This leads to stress failure of pulmonary capillaries in over-perfused areas of the lung, leading to a protein-rich pulmonary oedema. Evidence of alveolar epithelial inflammation manifests in both conditions. The role of defective reabsorption of sodium and water from the alveoli in HAPE led to the use of the inhaled beta-2agonist salmeterol in its prophylaxis, but to the best of our knowledge a similar approach has not been taken to date in COVID-19 patients. Microthrombi are reported in the pu
2019年冠状病毒病(COVID-19)全球大流行继续给人类生命、脆弱的卫生保健系统和国际旅行造成重大损失。在最初通过国际旅行途径迅速传播之后,持续社区传播现在是全世界的主要感染途径。这种新型冠状病毒感染最具挑战性的特征是,需要长时间通气的严重肺炎的高发率、症状前病毒的排出以及老年人群中不成比例的死亡率负担。对这种疾病的临床演变有了更清晰的认识。然而,我们对其发病机制的理解存在差距,影响了为最严重的患者提供靶向治疗的努力。作者在他们之间管理了COVID-19疾病和高原肺水肿(HAPE)的危重患者。最近在医学文献中提出的论点表明,COVID-19肺损伤可能与HAPE2具有共同的病理生理学,事实上,它们的临床表现确实存在有趣的相似之处。在这里,我们探讨这些离散条件之间的比较和对比点。HAPE历来被安第斯山脉的居民视为“山区的肺炎”HAPE和COVID-19的症状重叠,最初表现为干咳、发烧、呼吸困难和胸闷。同样在男性中更常见,严重的HAPE患者通常是心动过速、呼吸急促和明显的低氧血症。胸片上的斑片状结节浸润和CT上的周围磨玻璃影是这两种疾病的特征,尽管它们也可能在其他引起非心源性肺水肿的呼吸系统疾病中观察到急性呼吸窘迫综合征(ARDS)是COVID-19肺炎最严重病例的并发症,在严重HAPE中也有描述。宿主对SARS-CoV-2感染的炎症免疫反应的细胞因子风暴是部分患者发生严重疾病的关键,据报道,男性患者、老年人和已有疾病的患者的临床结果最差。有趣的是,不良临床结果在肥胖患者中也更常见。高海拔旅行者的缺氧性肺血管收缩反应(HPVR)和肺动脉高压的危险因素,包括肥胖和低通气综合征,可能会出现不均匀的肺小动脉血管收缩。这导致肺部过度灌注区域的肺毛细血管压力衰竭,导致富含蛋白质的肺水肿。肺泡上皮炎症的证据在这两种情况下都表现出来。在HAPE中,钠和水从肺泡重吸收缺陷的作用导致使用吸入β -2激动剂沙美特罗进行预防,但据我们所知,迄今为止尚未在COVID-19患者中采用类似的方法。据报道,在COVID-19患者的肺血管中存在微血栓,长期以来与HAPE相关,尽管在HAPE中,微血栓可能是一种附带现象,并且在HAPE过程中随后会出现急性炎症。有趣的是,先前的病毒性呼吸道感染的存在已在HAPE中得到确认。虽然病毒感染可能降低HAPE的阈值,但它不是水肿发展的必要条件。HAPE似乎是肺损伤的一个独特例子,http://ijtmgh.com国际旅行医学全球健康。2020年6月;8(2):89-90 doi 10.34172/ijtmgh.2020.14 TMGH国际旅行医学和全球健康杂志[J]
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引用次数: 2
Medical Tourism Overseas: A Challenge to Kuwait’s Healthcare System 海外医疗旅游:对科威特医疗体系的挑战
Pub Date : 2020-03-11 DOI: 10.34172/ijtmgh.2020.04
Bader Alhendi, Saleh Al-Saifi, A. Khaja
Introduction: The State of Kuwait spends large sums of governmental funds on sending patients abroad to receive medical treatment. This study aimed to explain the rationale behind receiving primary medical care overseas, given the expense and inconvenience, from the perspective of Kuwaiti patients whose applications were approved. Methods: The survey was designed based on recommendations from an expert panel of physicians working in Kuwait and aimed to give insight into outbound medical services as perceived by the Kuwaiti population. Using Google Forms, the survey was sent electronically to 1067 patients who received treatment abroad sponsored by the government in the year 2018, and 590 responses were returned. The study itself explored reasons for seeking treatment abroad, finances, preferred countries, and whether there were touristic reasons behind such practice. Data was analyzed using SPSS version 26. Results: Overall, males (52.3%) and females (47.7%) were equally represented in the study sample. The mean age for the study sample was 41±13.4 years. Approximately 45.3% of the respondents were married and had children. Of the remaining respondents, 21.9% were married with no children and 23.8% were single without children. All respondents received medical treatment abroad, and 52.3% of the married respondents and 47.7% of the single respondents stated that they received treatment once and more than once, respectively. Conclusion: Most Kuwaiti citizens do not have faith in the Kuwaiti medical system. Therefore, heavy investments are needed to send patients abroad.
导言:科威特国花费大量政府资金将病人送到国外接受治疗。本研究旨在从申请获得批准的科威特病人的角度,解释在费用和不便的情况下接受海外初级医疗的理由。方法:该调查是根据在科威特工作的医生专家小组的建议设计的,旨在深入了解科威特人口所感知的出境医疗服务。使用谷歌表格,该调查以电子方式发送给2018年在政府资助的国外接受治疗的1067名患者,收到了590份回复。该研究本身探讨了在国外寻求治疗的原因、经济状况、首选国家,以及这种做法背后是否有旅游原因。数据分析采用SPSS 26。结果:总体而言,研究样本中男性(52.3%)和女性(47.7%)的比例相等。研究样本的平均年龄为41±13.4岁。约45.3%的受访者已婚并有子女。其余受访者中,21.9%已婚无子女,23.8%单身无子女。所有受访者都在国外接受过治疗,52.3%的已婚受访者和47.7%的单身受访者分别表示接受过一次和不止一次治疗。结论:大多数科威特公民对科威特的医疗系统没有信心。因此,将患者送到国外需要大量投资。
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引用次数: 5
期刊
International Journal of Travel Medicine and Global Health
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