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Ambulance Use by International Travelers in Japan: A Retrospective Descriptive Study 日本国际旅行者使用救护车的回顾性描述性研究
Pub Date : 2020-03-11 DOI: 10.34172/ijtmgh.2020.02
Y. Oshita, Koki Tsuchiya, K. Ishikawa, K. Hirabayashi, T. Nemoto
Introduction: Reports indicate that 22%–64% of travelers experience some illness when in a foreign country. To date, no prior study has reported the use of ambulances by travelers or the epidemiology of travel-related injury. Methods: In this retrospective study, we aimed to describe ambulance use by international travelers, including the rates of travel-related injury and illness. To do so, ambulance dispatch data from January 1, 2010 to December 31, 2018 was used. Results: Overall, of the 43 201 cases of ambulance use during the study period, 524 (1.2%) were international travelers. Ambulance use by international travelers increased from 0.35% in 2010 (15/4311) to 2.54% in 2018 (125/4913), an average annual increase of 0.27%. Of the international travelers, 392 (74.8%) had minor complaints, 110 cases (21.0%) had moderate complaints, 280 (53.4%) had internal disease, and 223 cases (42.6%) had suffered trauma. Regarding location, 253 (48.3%) were from a hotel/lodge, 83 (15.8%) were from a road/parking, and 30 (5.7%) were in the forest/mountain. Conclusion: Most international travelers use ambulances for minor complaints, typically internal disease or trauma, and approximately half access the service from a hotel or lodge.
引言:报告显示,22%至64%的旅行者在外国时会经历一些疾病。迄今为止,没有任何研究报告旅行者使用救护车或旅行相关伤害的流行病学。方法:在这项回顾性研究中,我们旨在描述国际旅行者使用救护车的情况,包括与旅行相关的伤害和疾病的发生率。为此,使用了2010年1月1日至2018年12月31日的救护车调度数据。结果:总体而言,在研究期间使用救护车的43201例病例中,524例(1.2%)是国际旅行者。国际旅行者使用救护车的比例从2010年的0.35%(15/4311)增加到2018年的2.54%(125/4913),年均增长0.27%。在国际旅行者中,392例(74.8%)有轻微投诉,110例(21.0%)有中度投诉,280例(53.4%)有内科疾病,223例(42.6%)有创伤。关于地点,253人(48.3%)来自酒店/小屋,83人(15.8%)来自道路/停车场,30人(5.7%)在森林/山区。结论:大多数国际旅行者使用救护车处理轻微投诉,通常是内部疾病或创伤,大约一半的人从酒店或旅馆获得服务。
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引用次数: 1
New Coronavirus (2019-nCoV): An Insight Toward Preventive Actions and Natural Medicine 新型冠状病毒(2019-nCoV):对预防措施和自然医学的洞察
Pub Date : 2020-03-11 DOI: 10.34172/ijtmgh.2020.07
L. Khedmat
Today, one of the most critical health issues is the wide outbreak of novel coronavirus infection, which is so far affected 115 countries and territories all around the world. Presenting the possible risks and appropriate health preventive measures, as well as finding some bio-pharma strategies may open a bright horizon to alleviate the number of patients and the rate of disease transmission until discovering the vaccines and definitive treatments. In December 2019, novel coronavirus was initially recognized in Wuhan State, Hubei Province, China. This virus and its disease were called “SARS-CoV-2” and “coronavirus disease 2019 or COVID-19”, respectively. The COVID-19 was quickly spread in other Far East Asian countries and then to the Middle East and Europe.1 Similar to severe acute respiratory syndrome (SARS; 2002-2003) and the Middle East respiratory syndrome (MERS; 2012-ongoing), SARS-CoV-2 is the beta-coronavirus that originated from bats, causing fever, dry cough, and severe acute respiratory (SAR, e.g., breath shortness).2 Other common symptoms of this viral disease are fatigue, sputum production, myalgia or arthralgia, sore throat, headache, chills, nausea or vomiting, nasal congestion, diarrhea, and hemoptysis, and conjunctival congestion.2,3 In general, undesirable clinical outcomes are correlated to older adults and travelers with underlying health issues. Although the clinical diagnosis of COVID-19 in people can be resulted according to their signs, exposures, and chest imaging, nucleic acid testing of respiratory tract samples (eg, throat swabs) can be considered as a “gold standard” to confirm the viral infection.4,5 The COVID-19 outbreak not only can occur under the individual’s close contact with people carrying this virus but also being in areas where ongoing community spread of the virus. Due to the relatively high prevalence rate, many continuing efforts have been made to design guidelines to reduce outbreaks and encourage accurate and timely clinical reporting. From an epidemiologic viewpoint, the assessment of transmission modes, reproduction interval, and clinical spectrum of COVID-19 may have a vital role to prevent or control, and stop its incidence in communities. In this short time, no vaccine or efficient clinical treatment to fight COVID-19 infection has been yet explored. Therefore, the implementation of some preventive health measures as well as experiences of using medicinal herbs with excellent antiviral activities in controlling primary complications in patients will be important. The first step to prevent the spread of COVID-19 is the reduction or abolition of social gathering in areas with an elevated risk of exposure to the virus. A priority to reduce the disease rate is the quarantine of healthy individuals without symptoms at home, while suspected COVID-19 patients should be under quarantine at the assigned hospital and healthcare centers. The next step is the compliance of elementary cleanliness strategies ba
今天,最关键的卫生问题之一是新型冠状病毒感染的大范围爆发,迄今已影响到全球115个国家和地区。提出可能的风险和适当的健康预防措施,以及找到一些生物制药战略,可能会为减少患者人数和疾病传播率开辟一片光明的前景,直到发现疫苗和明确的治疗方法。2019年12月,中国湖北省武汉市首次发现新型冠状病毒。这种病毒及其疾病分别被称为“SARS-CoV-2”和“冠状病毒病2019或COVID-19”。COVID-19在其他远东国家迅速传播,然后传播到中东和欧洲。1类似于严重急性呼吸系统综合征(SARS;2002-2003年)和中东呼吸综合征(中东呼吸综合征;SARS-CoV-2是起源于蝙蝠的β冠状病毒,可引起发烧、干咳和严重急性呼吸道(SAR,如呼吸短促)这种病毒性疾病的其他常见症状有疲劳、咳痰、肌痛或关节痛、喉咙痛、头痛、寒战、恶心或呕吐、鼻塞、腹泻、咯血和结膜充血。2,3一般来说,不良的临床结果与有潜在健康问题的老年人和旅行者有关。尽管可以根据体征、暴露情况和胸部成像来对人进行COVID-19的临床诊断,但呼吸道样本(如咽拭子)的核酸检测可被视为确认病毒感染的“金标准”。4,5 COVID-19暴发不仅可能发生在个人与携带该病毒的人密切接触的情况下,而且也可能发生在病毒正在社区传播的地区。由于流行率相对较高,人们一直在努力制定准则,以减少疫情,并鼓励准确和及时的临床报告。从流行病学的角度来看,评估COVID-19的传播方式、繁殖间隔和临床谱可能对预防或控制和阻止其在社区发生具有至关重要的作用。在这么短的时间内,还没有开发出对抗COVID-19感染的疫苗或有效的临床治疗方法。因此,实施一些预防保健措施以及使用具有良好抗病毒活性的草药的经验对控制患者的原发性并发症将具有重要意义。防止COVID-19传播的第一步是减少或取消在病毒暴露风险高的地区的社交聚会。降低发病率的当务之急是在家隔离无症状的健康个体,疑似患者应在指定医院和保健中心进行隔离。下一步是遵守基于世界卫生组织(世卫组织)建议的基本清洁策略3,包括经常用肥皂水洗手20秒或更长时间,避免触摸口、鼻或眼睛,携带洗手液,用70%异丙醇喷洒接触表面,并佩戴防护口罩和手套,以满足有效的自我护理需求。由于COVID-19像其他β -冠状病毒一样可以通过增加营养缺乏来传播,因此通过补充维生素和矿物质来改善免疫系统可以作为防御COVID-19入侵的防御屏障。抗坏血酸是维持免疫力的第一个角色,尽管没有证据表明大剂量服用这种维生素可以预防COVID-19。研究还表明,增加细胞内Zn2+剂量能够http://ijtmgh.com [J] .旅行医学全球健康,2020,8(1):44-45 doi 10.34172/ijtmgh.2020.07 TMGH [J] .国际旅行医学与全球健康杂志
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引用次数: 16
A Systematic Review of the Factors Affecting the Growth of Medical Tourism in Iran 影响伊朗医疗旅游增长因素的系统评价
Pub Date : 2020-03-10 DOI: 10.34172/ijtmgh.2020.01
M. Gholami, A. K. H. Abadi, Shima Miladi, Marjan Gholami
Introduction: Planning in the field of medical tourism is of particular importance. The main objective of this research was to identify and analyze the factors affecting the growth of medical tourism in Iran. It could be a small step toward promoting entrepreneurship and increasing non-oil revenues in the country. Methods: Studies published in the Persian and English language during the years 2006-2019 in Science Direct, ProQuest, Springer, Medline, Scopus, Ovid, and SID databases were reviewed, and the findings were then compared. Results: A total of 75 articles out of 2631 unique publications were included in this study. Most articles reported studies performed for all patients, including the whole country (Iran) (n=22, 30%), Shiraz only (n=11, 15%), Tehran only (n=11, 15%), Mashhad only (n=6, 8%), Isfahan only (n=5, 6%), and Ardabil only (n=4, 5%). Conclusion: Given the history of Iranian hospitals in attracting foreign patients and the analysis of their status, there are many limitations in achieving a proper standing in the medical tourism industry. Strategies offered by various managers and authorities in tourism can lead to increased attraction of medical tourists to public and private hospitals in Shiraz, relying on the capabilities and potential of Shiraz and its health sectors, including climate and nature, cultural and historical attractions, renowned practitioners, advanced equipment, facilities, and methods, and thereby generating more foreign exchange earnings and employment.
导言:在医疗旅游领域的规划是特别重要的。本研究的主要目的是确定和分析影响伊朗医疗旅游增长的因素。这可能是促进创业和增加该国非石油收入的一小步。方法:回顾2006-2019年在Science Direct、ProQuest、施普林格、Medline、Scopus、Ovid和SID数据库中以波斯语和英语发表的研究,并对研究结果进行比较。结果:本研究共纳入2631篇独特出版物中的75篇。大多数文章报道了对所有患者进行的研究,包括全国(伊朗)(n= 22,30 %)、仅设拉子(n= 11,15 %)、仅德黑兰(n= 11,15 %)、仅马什哈德(n= 6,8 %)、仅伊斯法罕(n= 5,6 %)和仅阿达比尔(n= 4,5 %)。结论:鉴于伊朗医院吸引外国病人的历史和对其现状的分析,在医疗旅游业中取得适当地位存在许多限制。根据设拉子及其卫生部门的能力和潜力,包括气候和自然、文化和历史景点、著名的医生、先进的设备、设施和方法,旅游业各管理人员和当局提供的战略可以增加对设拉子公立和私立医院医疗游客的吸引力,从而产生更多的外汇收入和就业机会。
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引用次数: 13
Assessment of Risk of Type 2 Diabetes Among Adults of Banepa Municipality, Nepal: Community Based Cross-Sectional Study 尼泊尔Banepa市成年人2型糖尿病风险评估:基于社区的横断面研究
Pub Date : 2020-03-09 DOI: 10.34172/ijtmgh.2020.05
S. Thapa, Pratigya Kayastha, D. Mishra
Introduction: The prevalence of type 2 diabetes has been escalating worldwide, including low- and middle-income countries such as Nepal. Early detection of individuals at risk is of the utmost importance to prevent the escalating condition. This study used a simple, cost-effective screening tool known as the Indian Diabetes Risk Score (IDRS) in order to assess the proportion of risk groups and factors associated with it among the residents of Banepa municipality, a semi-urban area of central Nepal. Methods: A community-based cross-sectional study was conducted among 245 adults of Banepa municipality. Face to face interviews were conducted to collect the information through a pretested, semi-structured questionnaire. IDRS was used to identify the risk group for developing type 2 diabetes. Data were entered in Microsoft Excel 2010 and exported to SPSS v.11.5 for further analysis. Results: The proportion of people with high risk, moderate risk and low risk was 31%, 51.4% and 17.6%, respectively for developing type 2 diabetes. The analysis showed age (P < 0.01), education (P = 0.05), marital status (P = 0.01), body mass index (BMI) (P < 0.01), waist circumference (P < 0.01), physical activities (P < 0.01) and family history of diabetes (P < 0.04) were significantly associated with risk of type 2 diabetes. Conclusion: Nearly one-third of the study participants were in high-risk group and half of them were at moderate risk. This increasing trend of risk requires an urgent application of preventive measures through lifestyle modification.
引言:2型糖尿病的患病率在全球范围内不断上升,包括尼泊尔等中低收入国家。及早发现有风险的个人对于防止病情升级至关重要。这项研究使用了一种简单、成本效益高的筛查工具,即印度糖尿病风险评分(IDRS),以评估尼泊尔中部半城市地区Banepa市居民中风险群体的比例及其相关因素。方法:在Banepa市245名成年人中进行了一项基于社区的横断面研究。面对面访谈是通过预先测试的半结构化问卷收集信息。IDRS用于确定发展为2型糖尿病的风险组。数据输入到Microsoft Excel 2010中,并导出到SPSS v.11.5中进行进一步分析。结果:2型糖尿病高危人群、中危人群和低危人群的比例分别为31%、51.4%和17.6%。分析显示,年龄(P<0.01)、文化程度(P=0.05)、婚姻状况(P=0.01)、体重指数(BMI)(P<0.01),腰围(P<0.01)和体育活动(P<0.01)以及糖尿病家族史(P=0.04)与2型糖尿病的风险显著相关。结论:近三分之一的研究参与者属于高危人群,其中一半属于中等风险人群。这种风险的增加趋势需要通过改变生活方式紧急采取预防措施。
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引用次数: 1
Knowledge, Attitude and Practices Regarding Extreme Environments and Cold Adaptation at Extreme Altitudes on the Himalayan Ranges 关于喜马拉雅山脉极端海拔高度的极端环境和冷适应的知识、态度和实践
Pub Date : 2020-03-05 DOI: 10.34172/ijtmgh.2020.03
Inam Danish Khan
Introduction: Extreme-altitudes (5500 m/18045 ft and higher) pose environmental, psychophysiological, infrastructural, logistic, and ergonomic challenges that question explorer’s adaptability and mission-efficiency due to isolation, monotony, intimidating environment and terse health conditions. The assessment of an explorer’s comprehensive adaptability in extreme-altitudes is of paramount importance in ensuring mission-preparedness. Knowledge, attitude, and practices (KAP) of explorers staying on extreme-altitudes was assessed through personal interview technique. Methods: 125 healthy, acclimatized, mountain-trained explorers staying above 4570 m/15 000 ft in winter-season for at least 30 days on extreme-altitudes were assessed by a single cross-sectional study through personal interviews on KAP related to extreme-altitude and cold-adaptation. Results: Mean duration of stay on extreme-altitude was 55.7 days. All explorers knew about difficulties and health-problems at extreme-altitude. All explorers felt that mountain-training and acclimatization were beneficial. 92% felt that mission tenure of 90 days on the extreme-altitude was adequate. 92.8% felt they were adequately trained for the extreme-altitude; however, only 52% felt confident about health-training. 66.4% did preventive rewarming of extremities. 66.4% regularly smoked/chewed tobacco. 57.6% had sleep problems and 64% had altered appetite. 26.4% felt difficulties related to living conditions, infrastructure, and logistics. Conclusion: Explorers at extreme-altitude exhibited adequate knowledge and performed activities with progressive attitude and healthy practices. Explorers endured altered psychophysiology at extreme-altitude and regarded the utility of training and acclimatization programs. Knowledge-practice gap existed towards tobacco consumption. There was a felt need for the improvement of living conditions, infrastructure, logistics, and health-related training.
简介:极端海拔(5500米/18045英尺及以上)带来了环境、心理生理、基础设施、后勤和人体工程学方面的挑战,由于与世隔绝、单调乏味、令人生畏的环境和简洁的健康条件,这些挑战对探险家的适应性和任务效率提出了质疑。评估探险家在极端高度的综合适应性对于确保任务准备至关重要。通过个人访谈技术对居住在极端海拔地区的探险家的知识、态度和实践(KAP)进行了评估。方法:125名健康、适应环境、受过山地训练的探险家在冬季在4570m/15000英尺以上的极端海拔地区停留至少30天,通过对与极端海拔和寒冷适应相关的KAP的个人访谈,通过一项横断面研究进行评估。结果:在极端海拔的平均停留时间为55.7天。所有的探险者都知道在极端海拔地区的困难和健康问题。所有的探险家都觉得登山训练和适应环境是有益的。92%的人认为在极端高度上90天的任务期限是足够的。92.8%的人认为他们受过足够的极限海拔训练;然而,只有52%的人对健康训练有信心。66.4%的患者进行了四肢预防性复温。66.4%的人经常吸烟/咀嚼烟草。57.6%的人有睡眠问题,64%的人食欲不振。26.4%的人感到生活条件、基础设施和物流方面的困难。结论:在极端海拔的探索者表现出足够的知识,并以进步的态度和健康的实践进行活动。探险家们在极端海拔高度忍受着心理生理学的改变,并重视训练和适应计划的效用。烟草消费存在知识-实践差距。人们感到有必要改善生活条件、基础设施、后勤和与健康有关的培训。
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引用次数: 0
Education Level and Self-rated Health in the United States: Immigrants' Diminished Returns. 美国的教育水平和自评健康:移民的递减回报。
Pub Date : 2020-01-01 DOI: 10.34172/ijtmgh.2020.20
Shervin Assari, Maryver U Perez, Nay'Air Johnson, Nikesha R Williams, Esmeralda Carrillo, Leslye Garcia, Xiaxiang T Hollis

Introduction: Although education is among the major socioeconomic status (SES) resources that influence populations' and individuals' health, social marginalization may reduce the health gain that follows access to SES indicators such as education, a pattern called marginalization-related diminished return (MDR). The literature on MDRs, however, has been mainly derived from studies that have defined marginalization based on race, ethnicity, and sexual orientation. Thus, more research is needed on MDRs that may follow as a result of immigration. To extend what is known on immigration status related MDRs, this study compared a national sample of immigrants and non-immigrants for the effect of education on the poor self-rated health (SRH) of adults in the United States.

Methods: With a cross-sectional design, this study employed data from the 2015 National Health Interview Survey (NHIS), a survey that had enrolled 33,654 adults who were either immigrants (n = 6225; 18.5%) or non-immigrants (n = 27 429; 81.5%). The independent variable was education level, treated as a categorical variable. The dependent variable was SRH treated as a dichotomous variable. Race, ethnicity, age, gender, marital status, and region were the confounders. Immigration (nativity) was the moderator. Logistic regression was used for data analysis.

Results: Higher education credentials were associated with better SRH in the pooled sample; however, immigration showed a significant statistical interaction with education level (college graduation) on the outcome. This interaction was indicative of a smaller protective effect of college graduation on poor SRH among immigrants than non-immigrant adults.

Conclusion: In line with the MDRs framework, the effect of education on SRH is weaker for immigrants than for non-immigrant adults. There is a need to help highly educated immigrants to mobilize their human capital to secure their best health outcomes, similar to non-immigrants. Such strategies may require bold and innovative policy solutions to reduce discrimination against immigrants, so they can more effectively translate their education and human capital into tangible outcomes such as health.

导读:虽然教育是影响人口和个人健康的主要社会经济地位(SES)资源之一,但社会边缘化可能会减少获得教育等社会经济地位指标后获得的健康收益,这种模式称为与边缘化相关的回报减少(MDR)。然而,关于mdr的文献主要来源于基于种族、民族和性取向定义边缘化的研究。因此,需要对移民可能导致的mdr进行更多的研究。为了扩大对移民身份相关mdr的了解,本研究比较了移民和非移民的全国样本,以了解教育对美国成年人不良自评健康(SRH)的影响。方法:采用横断面设计,本研究采用2015年全国健康访谈调查(NHIS)的数据,该调查纳入了33,654名成年人,他们是移民(n = 6225;18.5%)或非移民(n = 27429;81.5%)。自变量为教育程度,作为分类变量。因变量SRH作为二分类变量处理。种族、民族、年龄、性别、婚姻状况和地区是混杂因素。移民(出生)是调节因素。采用Logistic回归进行数据分析。结果:在合并样本中,高等教育证书与较好的SRH相关;然而,移民与教育水平(大学毕业)在结果上表现出显著的统计交互作用。这种相互作用表明,与非移民成年人相比,大学毕业对移民中较差的SRH的保护作用较小。结论:与mdr框架一致,教育对移民性健康的影响弱于非移民成年人。有必要帮助受过高等教育的移民动员其人力资本,以确保他们的最佳健康结果,就像非移民一样。此类战略可能需要大胆和创新的政策解决办法,以减少对移民的歧视,使他们能够更有效地将其教育和人力资本转化为健康等有形成果。
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引用次数: 9
Household Income and Children's Depressive Symptoms: Immigrants' Diminished Returns. 家庭收入与儿童抑郁症状:移民收益递减
Pub Date : 2020-01-01 DOI: 10.34172/IJTMGH.2020.27
Shervin Assari

Introduction: Relative to socially privileged groups, socially marginalized people experience weaker health effects of household income and other economic resources, a pattern known as Minorities' Diminished Returns (MDRs). These MDRs are frequently seen in racial and ethnic minorities, but less is known about the relevance of such MDRs in immigrant families. To investigate the MDRs of household income on children's depression as a function of immigration, we compared non-immigrant and immigrant children for the effect of household income on children's depressive symptoms.

Methods: This cross-sectional study was conducted across multiple cities in the United States. Baseline data from the Adolescent Brain Cognitive Development (ABCD) study collected in 2018 was used. A total of 6,412 children between the ages of 9-10-year-old were included. The predictor variable was household income. The primary outcome was children's depression measured by the Child Behavior Checklist (CBCL). Race, ethnicity, age, sex, parental marital status, parental employment, and financial difficulties were the covariates. Immigration status was the effect modifier.

Results: Overall, high household income was associated with lower children's depressive symptoms. Immigration status showed a statistically significant interaction with household income on children's depression. This interaction term suggested that high household income has a smaller protective effect against depression for immigrant children than non-immigrant children.

Conclusion: The protective effect of household income against children's depression is diminished for immigrant than non-immigrant children.

导言:相对于社会特权群体,社会边缘人群的家庭收入和其他经济资源对健康的影响较弱,这种模式被称为少数群体收益递减(mdr)。这些mdr常见于种族和少数民族,但对移民家庭中此类mdr的相关性知之甚少。为了研究家庭收入对儿童抑郁的mdr作为移民的函数,我们比较了非移民和移民儿童家庭收入对儿童抑郁症状的影响。方法:这项横断面研究在美国多个城市进行。使用了2018年收集的青少年大脑认知发展(ABCD)研究的基线数据。共有6412名年龄在9-10岁之间的儿童被纳入研究。预测变量是家庭收入。主要结果是通过儿童行为检查表(CBCL)测量儿童抑郁。种族、民族、年龄、性别、父母婚姻状况、父母就业和经济困难是协变量。移民身份是影响因素。结果:总体而言,高家庭收入与较低的儿童抑郁症状相关。移民身份与家庭收入对儿童抑郁的影响具有统计学意义。这一相互作用项表明,与非移民儿童相比,高家庭收入对移民儿童抗抑郁的保护作用较小。结论:家庭收入对移民儿童抑郁的保护作用低于非移民儿童。
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引用次数: 5
Socioeconomic Status and Current Cigarette Smoking Status: Immigrants' Diminished Returns. 社会经济地位与当前吸烟状况:移民收益递减。
Pub Date : 2020-01-01 DOI: 10.34172/IJTMGH.2020.11
Shervin Assari

Introduction: Although socioeconomic status (SES) resources influence population and individual health behaviors, socially marginalized groups gain significantly less health from their SES indicators, such as education and income, compared to the socially privileged groups. This pattern is called marginalization-related diminished returns (MDRs). However, most of the MDRs literature is derived from studies that have defined marginalization based on race and ethnicity. As a result, more research is needed on MDRs due to immigration. To extend what is known about MDRs due to immigration, the current study compared a national sample of immigrants and non-immigrants for the effects of education and income on current cigarette smoking of adults in the United States.

Methods: This is a cross-sectional study. The 2015 National Health Interview Survey (NHIS) enrolled 14,149 individuals who were either immigrants (n=1977; 14.0%) or non-immigrants (n=12,166; 86.0%). The independent variables (IV) were education and income that were treated as categorical variables. The dependent variable was current cigarette smoking. Age, gender, race, ethnicity, marital status, employment, and region were confounders. Immigration was the moderator. Logistic regression was used for data analysis.

Results: High education and income were associated with lower odds of current cigarette smoking. However, immigration showed significant statistical interactions with both education and income. These interactions were suggestive of smaller protective effects of high education and income on current cigarette smoking for immigrant than non-immigrant adults.

Conclusion: In line with the MDRs, the effects of education and income on tobacco use is weaker for immigrant than non-immigrant adults.

虽然社会经济地位(SES)资源影响人口和个人健康行为,但与社会特权群体相比,社会边缘群体从其SES指标(如教育和收入)中获得的健康明显更少。这种模式被称为边缘化相关的收益递减(mdr)。然而,大多数mdr文献来源于基于种族和民族定义边缘化的研究。因此,需要对移民引起的mdr进行更多的研究。为了进一步了解移民导致的mdr,目前的研究比较了全国移民和非移民的样本,以了解教育和收入对美国成年人当前吸烟的影响。方法:这是一个横断面研究。2015年全国健康访谈调查(NHIS)招募了14,149人,他们要么是移民(n=1977;14.0%)或非移民(n=12,166;86.0%)。自变量(IV)为教育和收入,作为分类变量。因变量为当前吸烟情况。年龄、性别、种族、民族、婚姻状况、就业和地区是混杂因素。移民问题起到了调节作用。采用Logistic回归进行数据分析。结果:高教育程度和高收入与较低的吸烟几率相关。然而,移民在统计上与教育和收入都表现出显著的相互作用。这些相互作用表明,与非移民成年人相比,高学历和收入对移民当前吸烟的保护作用较小。结论:与mdr一致,教育和收入对移民烟草使用的影响弱于非移民成年人。
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引用次数: 16
Income and Mental Well-Being of Middle-Aged and Older Americans: Immigrants' Diminished Returns. 中老年美国人的收入和心理健康:移民的递减回报。
Pub Date : 2020-01-01 DOI: 10.34172/ijtmgh.2020.06
Shervin Assari

Introduction: Although income is among the major social determinants of mental health of middle-aged and older individuals, socially marginalized groups gain less health from their income and other socioeconomic status (SES) resources compared to socially privileged groups. This pattern is called marginalization-related diminished returns (MDRs). Most of the existing knowledge on MDRs, however, has been derived from studies that have defined marginalization based on race, ethnicity, or sexual orientation. As a result, very limited information exists on whether similar MDRs can be observed for middle-aged and older immigrants or not. Building on the MDRs framework, this study compared a national sample of immigrants and non-immigrants for the effects of income on the mental well-being of middle-aged and older adults in the United States.

Methods: This is a cross-sectional study. The 2015 National Health Interview Survey (NHIS) enrolled 14 149 middle-aged and older individuals who were either immigrants (n=1977; 14.0%) or non-immigrants (n=12 166; 86.0%). The independent variable (IV) was income that was treated as a continuous variable. The dependent variable was mental well-being, also treated as a continuous variable. Age, gender, race, ethnicity, education, marital status, employment, self-rated health, obesity, and region were confounders. Immigration (nativity status) was the moderator. Logistic regression was applied for data analysis.

Results: High income was associated with higher odds of good mental well-being in middle-aged and older adults. However, immigration showed a significant statistical interaction with income, which was suggestive of a smaller protective effect of high income on mental well-being for immigrant than non-immigrant middle-aged and older adults.

Conclusion: In line with MDRs, the association between income and mental well-being is weaker for immigrant than non-immigrant middle-aged and older adults. There is a need to help high income immigrants secure health outcomes similar to those of non-immigrants. Such changes may require bold and innovative economic, public, and social policies that help immigrants more effectively translate their income and socioeconomic resources into tangible outcomes such as mental well-being.

虽然收入是中老年个体心理健康的主要社会决定因素之一,但与社会特权群体相比,社会边缘群体从收入和其他社会经济地位(SES)资源中获得的健康较少。这种模式被称为边缘化相关的收益递减(mdr)。然而,大多数关于mdr的现有知识都来自于基于种族、民族或性取向定义边缘化的研究。因此,关于是否可以在中老年移民中观察到类似的mdr的信息非常有限。在mdr框架的基础上,本研究比较了移民和非移民的全国样本,以了解收入对美国中老年成年人心理健康的影响。方法:这是一个横断面研究。2015年全国健康访谈调查(NHIS)纳入了14149名中老年移民(n=1977;14.0%)或非移民(n=12 166;86.0%)。自变量(IV)是作为连续变量处理的收入。因变量是心理健康,也被视为一个连续变量。年龄、性别、种族、民族、教育、婚姻状况、就业、自评健康、肥胖和地区是混杂因素。移民(出生身份)是调节因素。采用Logistic回归进行数据分析。结果:在中老年人中,高收入与较高的心理健康几率相关。然而,移民与收入之间存在显著的统计交互作用,这表明高收入对移民心理健康的保护作用小于非移民中老年人。结论:与mdr一致,移民收入与心理健康之间的关联弱于非移民中老年人。有必要帮助高收入移民获得与非移民相似的健康结果。这种变化可能需要大胆和创新的经济、公共和社会政策,帮助移民更有效地将他们的收入和社会经济资源转化为有形的成果,如心理健康。
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引用次数: 38
Halogenation as a Strategy to Improve Antiplasmodial Activity: A Report of New 3-Alkylpyridine Marine Alkaloid Analogs 卤化作为提高抗疟原虫活性的策略:新的3-烷基吡啶海洋生物碱类似物的报道
Pub Date : 2019-12-15 DOI: 10.15171/ijtmgh.2019.27
Camila S Barbosa, Daniel Silqueira Martins Guimarães, Juliana Da Costa Alves, C. F. Brito, R. Ribeiro-Viana, F. Varotti, G. H. R. Viana
Introduction: Due to the emergence of resistance to antimalarial drugs as well as the lack of vaccination for malaria, there is an urgent demand for the development of new antimalarial alternatives. Recently, our research group developed a new set of 3-alkylpyridine marine alkaloid analogs, of which a compound known as compound 5 was found to be inactive against Plasmodium falciparum. Methods: Herein, we report a successful halogenation strategy to improve the antiplasmodial activity of compound 5 through the replacement of a hydroxyl group by chlorine (compound 6) and fluorine (compound 7) atoms. Results: Compounds 6 and 7 showed improved antiplasmodial activities (IC50 = 7.2 and 8.3 μM, respectively) 20 times higher than that of their precursor, compound 5 (IC50 = 210.7 μM). Ultraviolet-visible titration experiments demonstrated that halogenation of compound 5 did not alter its ability to bind its target, hematin. Conclusion: Halogenation can enhance the antiplasmodial activity of a compound without altering its mechanism of action.
引言:由于抗疟药物耐药性的出现以及缺乏疟疾疫苗接种,迫切需要开发新的抗疟替代品。最近,我们的研究小组开发了一套新的3-烷基吡啶海洋生物碱类似物,其中一种称为化合物5的化合物被发现对恶性疟原虫没有活性。方法:在此,我们报道了一种成功的卤化策略,通过氯(化合物6)和氟(化合物7)原子取代羟基来提高化合物5的抗等离子体活性。结果:化合物6和7的抗疟原虫活性(IC50分别为7.2和8.3μM)是其前体化合物5(IC50为210.7μM)的20倍。紫外-可见滴定实验表明,化合物5的卤化并没有改变其结合其靶标血红素的能力。结论:卤化能在不改变其作用机制的前提下提高化合物的抗疟原虫活性。
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引用次数: 1
期刊
International Journal of Travel Medicine and Global Health
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