Background: The coronavirus disease 2019 (Covid-19) outbreak is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Angiotensin-converting enzyme 2 (ACE-2) was rapidly identified as the critical functional receptor for SARS-CoV-2. ACE2 is well-known as a counter-regulator of the renin-angiotensin system (RAS) and plays a key role in the cardiovascular system. Given that ACE-2 functions as both a SARS-CoV-2 receptor and a RAS modulator, the treatment for Covid-19 presents a dilemma of how to limit virus entry but protect ACE-2 physiological functions. These will contribute to a deeper understanding of the complex mechanisms of underlying the relationship between the virus, ACE-2, and severity of disease provide guidance for virus intervention strategies. Aim: To study the effect of Covid-19 on the levels of some biomarker such as liver enzyme, ferritin, LDH, CRP and ACE-2 activity levels, and their relations with the severity of Covid-19 and the activity levels of angiotensin converting enzyme-2. Materials and Methods: This case-control study was conducted on 176 male subjects who diagnosed by physician and were divided into three groups: 59 of them were infected with severe covid-19, 54 of them were infected with moderate covid-19 and 63 of them were checked and obtained as apparently healthy control. Severe and moderate patients were collected from Al-Hayat tertiary center at Al-Hussein Medical City, Kerbala Health Directorates, Kerbala – Iraq during April, 2020- June, 2021 with matched age ranged between (23-88) years. In this study, the levels of ACE-2 was measured through enzyme-linked immunosorbent assays (ELISA) in sera from healthy volunteers as a control group, and patients with moderate Covid-19, patients with severe Covid-19. Anthropometric, biochemical data were analyzed and then measuring the levels of some biomarker such as liver enzyme, ferritin, LDH, and CRP activity levels. Results: The levels of ACE-2 were differing significantly among groups. However, the level of CRP, Ferritin and LDH were significantly higher in moderate Covid-19 and severe cases of Covid-19 groups compared to control indicating it to be an dependent predictor in the coronavirus disease and prognosis of disease. In contrast the severe infection was correlated with the age and chronic diseases such as pretention and T2DM.
{"title":"The Impact of Severe Covid-19 in Iraqi Patients on Serum Angiotensin-Converting Enzyme-2 Level and other Various Diagnosis Biomarkers","authors":"Suzan Haleem Kamel, Fadhil Jawad Al-Tu’ma, Riyadh Mohi Al-Saegh","doi":"10.22317/imj.v7i4.1263","DOIUrl":"https://doi.org/10.22317/imj.v7i4.1263","url":null,"abstract":"Background: The coronavirus disease 2019 (Covid-19) outbreak is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Angiotensin-converting enzyme 2 (ACE-2) was rapidly identified as the critical functional receptor for SARS-CoV-2. ACE2 is well-known as a counter-regulator of the renin-angiotensin system (RAS) and plays a key role in the cardiovascular system. Given that ACE-2 functions as both a SARS-CoV-2 receptor and a RAS modulator, the treatment for Covid-19 presents a dilemma of how to limit virus entry but protect ACE-2 physiological functions. These will contribute to a deeper understanding of the complex mechanisms of underlying the relationship between the virus, ACE-2, and severity of disease provide guidance for virus intervention strategies. \u0000Aim: To study the effect of Covid-19 on the levels of some biomarker such as liver enzyme, ferritin, LDH, CRP and ACE-2 activity levels, and their relations with the severity of Covid-19 and the activity levels of angiotensin converting enzyme-2. \u0000Materials and Methods: This case-control study was conducted on 176 male subjects who diagnosed by physician and were divided into three groups: 59 of them were infected with severe covid-19, 54 of them were infected with moderate covid-19 and 63 of them were checked and obtained as apparently healthy control. Severe and moderate patients were collected from Al-Hayat tertiary center at Al-Hussein Medical City, Kerbala Health Directorates, Kerbala – Iraq during April, 2020- June, 2021 with matched age ranged between (23-88) years. In this study, the levels of ACE-2 was measured through enzyme-linked immunosorbent assays (ELISA) in sera from healthy volunteers as a control group, and patients with moderate Covid-19, patients with severe Covid-19. Anthropometric, biochemical data were analyzed and then measuring the levels of some biomarker such as liver enzyme, ferritin, LDH, and CRP activity levels. \u0000Results: The levels of ACE-2 were differing significantly among groups. However, the level of CRP, Ferritin and LDH were significantly higher in moderate Covid-19 and severe cases of Covid-19 groups compared to control indicating it to be an dependent predictor in the coronavirus disease and prognosis of disease. In contrast the severe infection was correlated with the age and chronic diseases such as pretention and T2DM.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"120 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139387749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Riyadh Abdullah Jasim, Alaa Yousif Hassan, Sabah Abed Shadhar
Objectives: The aim of study is to assess the relationship between QT interval and IMVP, finding of an explanation for some cases of sudden death, presenting the association of symptoms of IMVP and some types of arrhythmias.
Methods: QTC intervals were measured in 43 patients with idiopathic mitral valve prolapse (11 men and 32 women with mean age 46±17 years). All patients underwent a clinical and echocardiographic examination, and ECG taking to assess the incidence of long QT in patients with IMVP.
Results: The results reveal a higher incidence of prolonged QT interval in patients with IMVP ,36 of 43 patients, while only 2 of 38 as control group. In addition, there were an increase incidence of arrhythmias with prolongation of QT interval.
Conclusion: This study indicates that the patients with IMVP at risk of arrhythmias, also these risks are higher in those patients with very long QT that may leads to serious ventricular arrhythmias.
{"title":"Analysis of QT interval in patients with Idiopathic mitral valve prolapse","authors":"Riyadh Abdullah Jasim, Alaa Yousif Hassan, Sabah Abed Shadhar","doi":"10.22317/imj.v7i3.1250","DOIUrl":"https://doi.org/10.22317/imj.v7i3.1250","url":null,"abstract":"Objectives: The aim of study is to assess the relationship between QT interval and IMVP, finding of an explanation for some cases of sudden death, presenting the association of symptoms of IMVP and some types of arrhythmias.
 Methods: QTC intervals were measured in 43 patients with idiopathic mitral valve prolapse (11 men and 32 women with mean age 46±17 years). All patients underwent a clinical and echocardiographic examination, and ECG taking to assess the incidence of long QT in patients with IMVP.
 Results: The results reveal a higher incidence of prolonged QT interval in patients with IMVP ,36 of 43 patients, while only 2 of 38 as control group. In addition, there were an increase incidence of arrhythmias with prolongation of QT interval.
 Conclusion: This study indicates that the patients with IMVP at risk of arrhythmias, also these risks are higher in those patients with very long QT that may leads to serious ventricular arrhythmias.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"50 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136136657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Abdalnabi Alwan Al-Tamimi, Omer Ali Rafiq Barawi, Rawand Mohammed Ali Kareem
Objectives: The intention of this study to compare functional outcomes between Total Hip Arthroplasty and Bipolar Hemi Arthroplasty for displaced femoral neck fracture after 3 months and 1 year from injury in elderly patients. Methods: Prospectively 43 patients were enrolled in this study, ages more than 60, twenty-four of them managed by Total Hip Arthroplasty, and 19 were managed by Bipolar Hemi Arthroplasty. These patients were followed up postoperatively for one year, at (3 and 12 months), to compare functional outcomes using Haris Hip Score. Results: Duration of operation was significantly higher in Total Hip Arthroplasty (98.54 min) versus (62.63 min) in the Bipolar Hemi Arthroplasty group, and intra-operative blood loss also considerably higher in Total Hip Arthroplasty (322.5 ml) than Bipolar Hemi Arthroplasty (178.42 ml). Regarding complications, there is no difference between the two groups; however, the incidence of mortality higher in the Bipolar Hemi Arthroplasty population. Average Haris Hip Score, pain and the motion were significantly better after three months and one-year follow-up in the Total Hip Arthroplasty group. The function was nearly the same at both groups after three months but after one-year of follow-up function significantly better (p-value <0.5) in the Total Hip Arthroplasty patients.Conclusion: Total Hip Arthroplasty provides better functional outcomes after three months and one year of follow-up than Bipolar Hemi Arthroplasty when used to manage femoral neck fracture for active old age patients. Bipolar Hemi Arthroplasty may be suitable for older inactive patients with narrow life expectancy with multiple comorbiditie
{"title":"Comparison of functional outcome between Bipolar Hemiarthroplasty and total Hip Arthroplasty for displaced femoral neck fractures in elderly patients","authors":"Ali Abdalnabi Alwan Al-Tamimi, Omer Ali Rafiq Barawi, Rawand Mohammed Ali Kareem","doi":"10.22317/imj.v7i3.1249","DOIUrl":"https://doi.org/10.22317/imj.v7i3.1249","url":null,"abstract":"Objectives: The intention of this study to compare functional outcomes between Total Hip Arthroplasty and Bipolar Hemi Arthroplasty for displaced femoral neck fracture after 3 months and 1 year from injury in elderly patients. Methods: Prospectively 43 patients were enrolled in this study, ages more than 60, twenty-four of them managed by Total Hip Arthroplasty, and 19 were managed by Bipolar Hemi Arthroplasty. These patients were followed up postoperatively for one year, at (3 and 12 months), to compare functional outcomes using Haris Hip Score. Results: Duration of operation was significantly higher in Total Hip Arthroplasty (98.54 min) versus (62.63 min) in the Bipolar Hemi Arthroplasty group, and intra-operative blood loss also considerably higher in Total Hip Arthroplasty (322.5 ml) than Bipolar Hemi Arthroplasty (178.42 ml). Regarding complications, there is no difference between the two groups; however, the incidence of mortality higher in the Bipolar Hemi Arthroplasty population. Average Haris Hip Score, pain and the motion were significantly better after three months and one-year follow-up in the Total Hip Arthroplasty group. The function was nearly the same at both groups after three months but after one-year of follow-up function significantly better (p-value <0.5) in the Total Hip Arthroplasty patients.Conclusion: Total Hip Arthroplasty provides better functional outcomes after three months and one year of follow-up than Bipolar Hemi Arthroplasty when used to manage femoral neck fracture for active old age patients. Bipolar Hemi Arthroplasty may be suitable for older inactive patients with narrow life expectancy with multiple comorbiditie","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"308 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136135145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Firdous Salih M. Al-Jiboury, Abid Ahmed Salman, Ashoor R Sarhat
Background:- Neonatal jaundice is a common cause of early life admission to neonatal care unite . High rate of neonatal jaundice is physiological type that need conservative management and follow up to prevent lethal complications . A low rate of neonatal jaundice is pathological type that need treatment of the underlying causes and follow up.
Patients and Methods:- The current study was a cross sectional study involved 312 neonates (204 of them with jaundice and 108 without jaundice ) ,attending Salahaddin General hospital from 1 st October 2022 to 30th January 2023. The Study sample was convenient . Jaundiced and Non-jaundiced neonates were enrolled into the study when they enter the wards of paediatrics and neonatal intensive care unites in Salahaddin General Hospital and those visits outpatient clinics of pediatricians and the general population during a free neonatal jaundice screening campaign in Tikrit City.
Results:- The prevalence of neonatal jaundice is (9.2%). The most frequent cases was having total serum bilirubin(TSB) level ≤18 milligram/dc liter(mgdl) (84.8%).The mean ±standard deviation (SD) of hyperbilirubinemia level is (15 ± 3.366 mgdl ) and the high TSB level was reported among male gender(58.3%).The percent of preterm babies was (33.3%) of total sample .The most cases had normal weight (66.7%) at time of delivery ,mean ±SD of weight is (2698.5±693.54gram) and had no bruises or hematoma as cephalohematoma (89.2%).There was no blood diseases in about (72.5%) of total sample and no history of infection in (68.1%) of cases. The most frequent methods of feeding was breast feeding (39.7%). Regarding to time of appearance of jaundice, the most frequent cases were among those with age group (≤5 days )(89.7%) .The mean±SD for age of neonate at time of admission is (6.2±3.6 day).Blood group incompatibility(ABO incompatibility) was found in (60.8%) of cases with TSB level ≤18 mg/dl and (11.3%) of cases of TSB level <18 mgdl . While Rhesus incompatibility(Rh incompatibility) was found in (13.2%) of cases with TSB level ≤18 mg/dl .
Conclusion:-The study revealed that a prevalence of neonatal jaundice is (9.2%) in Tikrit City. The most frequent cases were those with age group (≤5 days ) at time of appearance of jaundice (89.7%). The cases that had blood disease were (72.5%) with significant difference and The most recurrent cases were full term babies (66.7%) ,while preterm babies (33.3%). The most frequent cases of neonatal jaundice according to TSB≤18 mg/dl was among those with ABO incompatibility (60.8%) and Rh compatibility (71.6%).
{"title":"Epidemiology Of Neonatal Jaundice In Tikrit City: According to Neonatal Risk Factors ,2022-2023","authors":"Firdous Salih M. Al-Jiboury, Abid Ahmed Salman, Ashoor R Sarhat","doi":"10.22317/imj.v7i3.1254","DOIUrl":"https://doi.org/10.22317/imj.v7i3.1254","url":null,"abstract":"Background:- Neonatal jaundice is a common cause of early life admission to neonatal care unite . High rate of neonatal jaundice is physiological type that need conservative management and follow up to prevent lethal complications . A low rate of neonatal jaundice is pathological type that need treatment of the underlying causes and follow up. 
 Patients and Methods:- The current study was a cross sectional study involved 312 neonates (204 of them with jaundice and 108 without jaundice ) ,attending Salahaddin General hospital from 1 st October 2022 to 30th January 2023. The Study sample was convenient . Jaundiced and Non-jaundiced neonates were enrolled into the study when they enter the wards of paediatrics and neonatal intensive care unites in Salahaddin General Hospital and those visits outpatient clinics of pediatricians and the general population during a free neonatal jaundice screening campaign in Tikrit City.
 Results:- The prevalence of neonatal jaundice is (9.2%). The most frequent cases was having total serum bilirubin(TSB) level ≤18 milligram/dc liter(mgdl) (84.8%).The mean ±standard deviation (SD) of hyperbilirubinemia level is (15 ± 3.366 mgdl ) and the high TSB level was reported among male gender(58.3%).The percent of preterm babies was (33.3%) of total sample .The most cases had normal weight (66.7%) at time of delivery ,mean ±SD of weight is (2698.5±693.54gram) and had no bruises or hematoma as cephalohematoma (89.2%).There was no blood diseases in about (72.5%) of total sample and no history of infection in (68.1%) of cases. The most frequent methods of feeding was breast feeding (39.7%). Regarding to time of appearance of jaundice, the most frequent cases were among those with age group (≤5 days )(89.7%) .The mean±SD for age of neonate at time of admission is (6.2±3.6 day).Blood group incompatibility(ABO incompatibility) was found in (60.8%) of cases with TSB level ≤18 mg/dl and (11.3%) of cases of TSB level <18 mgdl . While Rhesus incompatibility(Rh incompatibility) was found in (13.2%) of cases with TSB level ≤18 mg/dl .
 Conclusion:-The study revealed that a prevalence of neonatal jaundice is (9.2%) in Tikrit City. The most frequent cases were those with age group (≤5 days ) at time of appearance of jaundice (89.7%). The cases that had blood disease were (72.5%) with significant difference and The most recurrent cases were full term babies (66.7%) ,while preterm babies (33.3%). The most frequent cases of neonatal jaundice according to TSB≤18 mg/dl was among those with ABO incompatibility (60.8%) and Rh compatibility (71.6%).","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"106 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136135142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rana M. Hameed, Ahmed Dawood Salman, Atheer Hameed Odda
Objective: The main objectives of this study was to Prepare and study the structural features of chitosan/iron oxide nanoparticles CS-FeO NPs and to examine the applications of chitosan nanoparticles as a lipid-lowering agent in children with nephrotic syndrome
Method: The preparation processes for nanoparticles are described in depth. Chitosan nanoparticle applications are shown. X-ray diffraction patterns (XRD) indicated that the magnetic Fe3O4 nanoparticles were pure Fe3O4 with a spinel structure and the coating of chitosan did not result in a phase change.
Results: The coating of CTS onto the Fe3O4 nanoparticles was also demonstrated by the measurement of Fourier transform infrared (FTIR) spectra. Magnetic measurement revealed that the saturated magnetization of the Fe3O4–chitosan nanoparticles reached +18.3 mV and the nanoparticles showed the characteristics of superparamagnetic.
Conclusion: Magnetic Fe3O4–chitosan nanoparticles were prepared successfully by the covalent binding of CTS on the Fe3O4 nanoparticles. These microspheres was apply to the magnetic-field-assisted lipid lowering processes.
{"title":"Chitosan-iron oxide nanoparticle preparation and performance as a lipid-lowering agent in serum patients with nephrotic syndrome","authors":"Rana M. Hameed, Ahmed Dawood Salman, Atheer Hameed Odda","doi":"10.22317/imj.v7i3.1253","DOIUrl":"https://doi.org/10.22317/imj.v7i3.1253","url":null,"abstract":"Objective: The main objectives of this study was to Prepare and study the structural features of chitosan/iron oxide nanoparticles CS-FeO NPs and to examine the applications of chitosan nanoparticles as a lipid-lowering agent in children with nephrotic syndrome
 Method: The preparation processes for nanoparticles are described in depth. Chitosan nanoparticle applications are shown. X-ray diffraction patterns (XRD) indicated that the magnetic Fe3O4 nanoparticles were pure Fe3O4 with a spinel structure and the coating of chitosan did not result in a phase change.
 Results: The coating of CTS onto the Fe3O4 nanoparticles was also demonstrated by the measurement of Fourier transform infrared (FTIR) spectra. Magnetic measurement revealed that the saturated magnetization of the Fe3O4–chitosan nanoparticles reached +18.3 mV and the nanoparticles showed the characteristics of superparamagnetic.
 Conclusion: Magnetic Fe3O4–chitosan nanoparticles were prepared successfully by the covalent binding of CTS on the Fe3O4 nanoparticles. These microspheres was apply to the magnetic-field-assisted lipid lowering processes.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136135379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Non-alcoholic fatty liver disease (NAFLD) has a global prevalence of 25% and is one of the main causes of cirrhosis and hepatocellular carcinoma. Recently, the stress response protein mesencephalon-astrocyte-derived neurotrophic factor (MANF) has been shown to regulate hepatic and systemic metabolic homeostasis.
Objectives: The main purpose of this study is to investigate the relationship between mesencephalon-astrocyte-derived neurotrophic factor levels with other anthropometric indicators, and its function in the pathogenesis of non-alcoholic fatty liver disease.
Materials and Methods: A total of 120 patients with ages ranging between 40 to 73 years were included in this study and their serum samples were collected and kept at -2 °C. The liver function test, lipid profile, and albumin were determined using the automated biochemistry analyzer, while the mesencephalic astrocyte-derived neurotrophic factor biomarker was determined by the ELIZA technique.
Results: Our study showed that MANF levels decrease with age, and decreased MANF levels are associated with inflammatory phenotypes. The mean levels of ALT, ALP, AST, TSB, and the ALT/AST ratio in the non-alcoholic fatty liver patients were significantly higher than that for the non-fatty liver patients. As well, the mean level of MANF in the non-fatty liver patients was 305.25 ± 110.49 mg/dl which was significantly higher in the non-alcoholic fatty liver group (157.52). (p ≤ 0.001)
Conclusion: A novel finding of our study is that the reduction of serum MANF levels is strongly associated with the pathogenesis of non-alcoholic fatty liver disorders and could be used as a potential therapeutic target in the treatment of hepatic disorders.
{"title":"Role of Mesencephalic Astrocyte-Derived Neurotrophic Factor Levels in Pathogenesis of Non-Alcoholic Fatty Liver","authors":"Fadhil Jawad Al-Tu’ma, Ibtihal Hameed Gazi, Atheer Hameid Odda, Jawad Fadhil Al-Tu’ma","doi":"10.22317/imj.v7i3.1252","DOIUrl":"https://doi.org/10.22317/imj.v7i3.1252","url":null,"abstract":"Background: Non-alcoholic fatty liver disease (NAFLD) has a global prevalence of 25% and is one of the main causes of cirrhosis and hepatocellular carcinoma. Recently, the stress response protein mesencephalon-astrocyte-derived neurotrophic factor (MANF) has been shown to regulate hepatic and systemic metabolic homeostasis.
 Objectives: The main purpose of this study is to investigate the relationship between mesencephalon-astrocyte-derived neurotrophic factor levels with other anthropometric indicators, and its function in the pathogenesis of non-alcoholic fatty liver disease.
 Materials and Methods: A total of 120 patients with ages ranging between 40 to 73 years were included in this study and their serum samples were collected and kept at -2 °C. The liver function test, lipid profile, and albumin were determined using the automated biochemistry analyzer, while the mesencephalic astrocyte-derived neurotrophic factor biomarker was determined by the ELIZA technique.
 Results: Our study showed that MANF levels decrease with age, and decreased MANF levels are associated with inflammatory phenotypes. The mean levels of ALT, ALP, AST, TSB, and the ALT/AST ratio in the non-alcoholic fatty liver patients were significantly higher than that for the non-fatty liver patients. As well, the mean level of MANF in the non-fatty liver patients was 305.25 ± 110.49 mg/dl which was significantly higher in the non-alcoholic fatty liver group (157.52). (p ≤ 0.001)
 Conclusion: A novel finding of our study is that the reduction of serum MANF levels is strongly associated with the pathogenesis of non-alcoholic fatty liver disorders and could be used as a potential therapeutic target in the treatment of hepatic disorders.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"23 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136135147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This aims to explore the prevalence of obesity and overweight among Palestinian students in universities, and their relationship with sociodemographic factors, dietary habits, psychosocial factors, and physical activity level. Methods: A total sample of 1243 students, 772 (62.1%) females and 471 (37.9%) males, were included in the final analysis. The nutritional status was assessed using anthropometric measurements and dietary habits. Weight status was defined according to BMI WHO cut off points. Anxiety, stress, and depression were assessed using Arabic version of the Depression Anxiety Stress Scales. A short form of the Arabic version of IPAQ questionnaire was used to assess physical activity level. Results: The results revealed that obesity prevalence was 3.3% and overweight was 16.10% among the students. Obesity was significantly more common among males, and those who are studying scientific specialization. Weigh status was significantly related to anxiety (p<0.05). Among the psychosocial factors, students with normal weight had significantly higher anxiety scores than obese or overweight students (p<0.05). Obesity and overweight were significantly associated with lower self-satisfaction (P<0.05). Conclusion: The prevalence of obesity and overweight was low among the study sample. In spite of this, there is a need to promote intervention educational programs to improve their lifestyle in terms of physical activity and dietary habits.
{"title":"Factors associated with obesity among Palestinian university students in west bank","authors":"Manal Badrasawi, Souzan Zidan, Azza Dabous, Monjed Samuh","doi":"10.22317/imj.v7i3.1248","DOIUrl":"https://doi.org/10.22317/imj.v7i3.1248","url":null,"abstract":"Objective: This aims to explore the prevalence of obesity and overweight among Palestinian students in universities, and their relationship with sociodemographic factors, dietary habits, psychosocial factors, and physical activity level. Methods: A total sample of 1243 students, 772 (62.1%) females and 471 (37.9%) males, were included in the final analysis. The nutritional status was assessed using anthropometric measurements and dietary habits. Weight status was defined according to BMI WHO cut off points. Anxiety, stress, and depression were assessed using Arabic version of the Depression Anxiety Stress Scales. A short form of the Arabic version of IPAQ questionnaire was used to assess physical activity level. Results: The results revealed that obesity prevalence was 3.3% and overweight was 16.10% among the students. Obesity was significantly more common among males, and those who are studying scientific specialization. Weigh status was significantly related to anxiety (p<0.05). Among the psychosocial factors, students with normal weight had significantly higher anxiety scores than obese or overweight students (p<0.05). Obesity and overweight were significantly associated with lower self-satisfaction (P<0.05). Conclusion: The prevalence of obesity and overweight was low among the study sample. In spite of this, there is a need to promote intervention educational programs to improve their lifestyle in terms of physical activity and dietary habits.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"45 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136134973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Evaluate the surgical success and postoperative hearing outcome of type 1 tympanoplasty using temporalis fascia graft in its wet versus its dry fashion.
Methods: A prospective randomized comparative study which was conducted in Sulaimanyah otorhinolaryngology & head and neck surgery centre between October 2018 and November 2019 on patients with sign and symptom of tympanic membrane perforation who underwent type1 tympanoplasty in 2 groups in whom wet graft used in one group, and dry graft used in the other group, these patient followed up after 3 month for graft take and postoperative hearing.
Results: Of the 29 patients included in the study in 15 of them dry graft used and the graft take was 86.7% and in 14 of the wet graft used and the take rate was78.6%, postoperative mean hearing gain was 14.07 dB in the dry graft group and 12 dB in the wet graft group, all cases in both group had improvement in hearing (P value= 0.001), but neither wet nor dry was better than the other (P value=0.345). Graft take and hearing gain in different site and size of perforations were not significant, graft take rate was 100% in small size and 50% in subtotal perforation, hearing gain was 14.50 dB for subtotal perforation and 9.50 dB in small size perforation, mean time of wet graft group with 75.36 minutes were shorter significantly than the dry graft with 95 minutes with (P value=0.001).
Conclusion: The Nature of the temporalis fascia not affect the outcome type 1 tympanoplasty, and temporalis fascia is a good graft material regarding the success rate and hearing gain, however the wet Temporalis fascia graft use may shorten the operation time.
{"title":"Surgical and Audiological outcomes of Wet versus Dry Temporalis Fascia Graft in Type 1 Tympanoplasty","authors":"Hemn Hussain Othman, Hiwa Asaad Abdulkareem","doi":"10.22317/imj.v7i3.1251","DOIUrl":"https://doi.org/10.22317/imj.v7i3.1251","url":null,"abstract":"Objectives: Evaluate the surgical success and postoperative hearing outcome of type 1 tympanoplasty using temporalis fascia graft in its wet versus its dry fashion.
 Methods: A prospective randomized comparative study which was conducted in Sulaimanyah otorhinolaryngology & head and neck surgery centre between October 2018 and November 2019 on patients with sign and symptom of tympanic membrane perforation who underwent type1 tympanoplasty in 2 groups in whom wet graft used in one group, and dry graft used in the other group, these patient followed up after 3 month for graft take and postoperative hearing.
 Results: Of the 29 patients included in the study in 15 of them dry graft used and the graft take was 86.7% and in 14 of the wet graft used and the take rate was78.6%, postoperative mean hearing gain was 14.07 dB in the dry graft group and 12 dB in the wet graft group, all cases in both group had improvement in hearing (P value= 0.001), but neither wet nor dry was better than the other (P value=0.345). Graft take and hearing gain in different site and size of perforations were not significant, graft take rate was 100% in small size and 50% in subtotal perforation, hearing gain was 14.50 dB for subtotal perforation and 9.50 dB in small size perforation, mean time of wet graft group with 75.36 minutes were shorter significantly than the dry graft with 95 minutes with (P value=0.001).
 Conclusion: The Nature of the temporalis fascia not affect the outcome type 1 tympanoplasty, and temporalis fascia is a good graft material regarding the success rate and hearing gain, however the wet Temporalis fascia graft use may shorten the operation time.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"23 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136135143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jihad M. Hadi, Shanya B. Shawkat, Hwda Gh. Rauf, Soma A. Hama Karim, Ayman M. Mustafa, Soz N. Muhammad, Mhamad S. Abdullah
Background: Smoking is a serious issue for global public health, and the prevalence of smoking use is the leading cause of early mortality globally. Serum ferritin, an intracellular protein that stores and releases iron, is considered one of the most important clinical biomarkers to assess iron status.
Aim: The current study aims to examines the effect of smoking on serum ferritin levels of adult populations in Sulaymaniyah.
Methods: The study was conducted on 80 smokers and 20 non-smokers, totally 100 persons. Their ages ranged from 18 to 65 years.
Results: Result showed that the majority of smokers had elevated ferritin levels. A p-value of less than 0.05 indicated a significant difference in ferritin levels between smokers and non-smokers groups. The average ferritin level among smoker group was 227.40 mg/L, while the average ferritin level among non-smokers group was 118.3 mg/L. Regarding the associated between age groups and average ferritin levels, the average ferritin level is highest in the age groups between 51-61 years old. In addition, obesity may play a role in raising ferritin levels, people with obese conditions (BMI > 30) have the highest average ferritin levels than others.
Conclusion: This study provides evidence that smoking negatively affect serum ferritin levels, since increases in mean ferritin levels are very striking in smoking and obese group.
{"title":"Effects of Smoking on Serum Ferritin levels in adult population living in Sulaymaniyah, Iraq: A Retrospective Cross-sectional Study","authors":"Jihad M. Hadi, Shanya B. Shawkat, Hwda Gh. Rauf, Soma A. Hama Karim, Ayman M. Mustafa, Soz N. Muhammad, Mhamad S. Abdullah","doi":"10.22317/imj.v7i3.1255","DOIUrl":"https://doi.org/10.22317/imj.v7i3.1255","url":null,"abstract":"Background: Smoking is a serious issue for global public health, and the prevalence of smoking use is the leading cause of early mortality globally. Serum ferritin, an intracellular protein that stores and releases iron, is considered one of the most important clinical biomarkers to assess iron status.
 Aim: The current study aims to examines the effect of smoking on serum ferritin levels of adult populations in Sulaymaniyah. 
 Methods: The study was conducted on 80 smokers and 20 non-smokers, totally 100 persons. Their ages ranged from 18 to 65 years.
 Results: Result showed that the majority of smokers had elevated ferritin levels. A p-value of less than 0.05 indicated a significant difference in ferritin levels between smokers and non-smokers groups. The average ferritin level among smoker group was 227.40 mg/L, while the average ferritin level among non-smokers group was 118.3 mg/L. Regarding the associated between age groups and average ferritin levels, the average ferritin level is highest in the age groups between 51-61 years old. In addition, obesity may play a role in raising ferritin levels, people with obese conditions (BMI > 30) have the highest average ferritin levels than others.
 Conclusion: This study provides evidence that smoking negatively affect serum ferritin levels, since increases in mean ferritin levels are very striking in smoking and obese group.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"51 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136135669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Handern M. Rasheed, Amanj H. Ali, Nashaddin A. Mohammed
Objectives: This study aimed to evaluate the efficacy of surgical decompression of the lumbar spinal canal, a procedure involving the removal of ligamentum and other degenerated elements causing pressure on the thecal sac, nerve roots, and neurovascular structures. The procedure is considered essential for patients experiencing neurogenic claudication, low back pain, lower limb pain and paresthesia, and decreased walking performance, to effectively decompress the lumbar canal. Methods: A retrospective analysis was conducted on patients who underwent surgical decompression at Shar hospital between 2018 and 2020. A total of 57 eligible patients were followed up to assess the outcomes related to neurogenic claudication and walking ability after 12-24 months postoperatively. Results: The postoperative results for neurogenic claudication and walking ability were found to be satisfactory in nearly three-quarters of the cases. The duration of symptoms significantly influenced the results, while factors such as gender, body mass index, smoking history, the number of stenosed levels operated, and the type of stenosis did not show significant impact. Conclusion: Surgical decompression for degenerative lumbar canal stenosis is a relatively low-risk procedure with a very high rate of postoperative patient satisfaction regarding neurogenic claudication and improved walking distance. These positive outcomes are particularly evident when the procedure is performed promptly, by an experienced surgeon, and with appropriate patient selection.
{"title":"Surgical outcome of “Neurogenic claudication and walking limitation” due to degenerative Lumbar spinal canal stenosis","authors":"Handern M. Rasheed, Amanj H. Ali, Nashaddin A. Mohammed","doi":"10.22317/imj.v7i2.1242","DOIUrl":"https://doi.org/10.22317/imj.v7i2.1242","url":null,"abstract":"Objectives: This study aimed to evaluate the efficacy of surgical decompression of the lumbar spinal canal, a procedure involving the removal of ligamentum and other degenerated elements causing pressure on the thecal sac, nerve roots, and neurovascular structures. The procedure is considered essential for patients experiencing neurogenic claudication, low back pain, lower limb pain and paresthesia, and decreased walking performance, to effectively decompress the lumbar canal. \u0000Methods: A retrospective analysis was conducted on patients who underwent surgical decompression at Shar hospital between 2018 and 2020. A total of 57 eligible patients were followed up to assess the outcomes related to neurogenic claudication and walking ability after 12-24 months postoperatively. \u0000Results: The postoperative results for neurogenic claudication and walking ability were found to be satisfactory in nearly three-quarters of the cases. The duration of symptoms significantly influenced the results, while factors such as gender, body mass index, smoking history, the number of stenosed levels operated, and the type of stenosis did not show significant impact. \u0000Conclusion: Surgical decompression for degenerative lumbar canal stenosis is a relatively low-risk procedure with a very high rate of postoperative patient satisfaction regarding neurogenic claudication and improved walking distance. These positive outcomes are particularly evident when the procedure is performed promptly, by an experienced surgeon, and with appropriate patient selection.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90100946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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