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QT interval analysis in individuals with idiopathic mitral valve prolapse 特发性二尖瓣脱垂患者的QT间期分析
Pub Date : 2023-03-26 DOI: 10.22317/imj.v7i1.1221
Riyadh Abdullah Jasim, A. Y. Hassan, Sabah Abed Shadhar
Objectives: The goals of the study are to determine whether or not there is a correlation between the QT interval and IMVP, to provide an explanation for sudden cardiac death in some cases, and to show how IMVP symptoms are linked to certain arrhythmias. Methods: QTC intervals were measured in 43 patients with idiopathic mitral valve prolapse (11 men and 32 women with mean age 46±17 years). All patients underwent a clinical and echocardiographic examination, and ECG taking to assess the incidence of long QT in patients with IMVP. Results: The data show that 36 of the 43 patients with IMVP have a prolonged QT interval, while only 2 of the 38 patients in the control group have. There was also an uptick in arrhythmia cases when the QT interval was prolonged. Conclusion: Individuals with IMVP have an increased risk of arrhythmias, and this risk is even greater in patients with very long QT, which can cause life-threatening ventricular arrhythmias, as shown by this study.
目的:本研究的目的是确定QT间期与IMVP之间是否存在相关性,为某些病例的心源性猝死提供解释,并显示IMVP症状与某些心律失常之间的联系。方法:对43例特发性二尖瓣脱垂患者(男11例,女32例,平均年龄46±17岁)进行QTC间隔测定。所有患者均接受临床和超声心动图检查,并进行心电图检查以评估IMVP患者长QT间期的发生率。结果:43例IMVP患者中有36例QT间期延长,对照组38例中仅有2例QT间期延长。当QT间期延长时,心律失常病例也有上升趋势。结论:本研究显示,IMVP患者发生心律失常的风险增加,QT超长患者的风险更大,QT超长可导致危及生命的室性心律失常。
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引用次数: 0
Assessment of the Antibacterial Activity of Lavender cultivated in Tasmania and identifying its geographical and botanical origins 塔斯马尼亚种植的薰衣草抗菌活性评估及其地理和植物起源的鉴定
Pub Date : 2023-03-26 DOI: 10.22317/imj.v7i1.1228
Hanaa Abbas Yamani
Objectives: This study compared the antimicrobial activity of lavender honey manufactured in Tasmania Australia with Manuka honey as a control. Methods: Lavender essential oil also examined for antimicrobial activity. The volatile compounds were identified to find the bioactive compounds responsible for the antibacterial activity. Next, the volatile data of the Lavender honey and essential oil from Lavandula angustifolia cultivated in Tasmania, were used to indicate the geographical and botanical origins of the using head space solid-phase micro extraction (HS SPME) and Gas Chromatography Mass Spectrometry (GC-MS).  The antimicrobial activity of Lavender Honey and essential oil from Tasmania were examined using the broth micro-dilution method to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Bacteriostatic end points were determined spectrophotometrically, then bactericidal end points were determined by plating. Methicillin-sensitive and methicillin-resistant strains of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were used in this study. Results: Lavender honey showed similar, and in some bacterial species, slightly higher activity than Manuka honey. The MICs and MBCs for lavender honey ranged from 6.25% to 25% v/v compared to MICs of Manuka honey which ranged between 12.5% and 25% v/v. The MIC and MBC values of lavender honey and Manuka honey against P. aeruginosa were 12.5% v/v and 25% v/v respectively. The corresponding values for a methicillin-sensitive strain of S. aureus were 6.25% v/v and 12.5% v/v respectively. The MIC and MBC were the same for both honey for E. coli equal to 12.5 % v/v and for MRSA equal to 6.25 % v/v. The growth of S. aureus, including MRSA and E. coli completely inhibited by Lavender E. oil at concentrations of 2.25%. Whereas, the growth of P. aeruginosa partly inhibited by the same concentrations. Use of a spectrophotometer facilitated reading of MIC values. Conclusion: These results suggest that lavender honey and essential oil could be used as an antimicrobial agent for infections caused by S. aureus including MRSA, E. coli and P. aeruginosa.
目的:本研究比较了澳大利亚塔斯马尼亚生产的薰衣草蜂蜜和麦卢卡蜂蜜作为对照的抗菌活性。方法:测定薰衣草精油的抑菌活性。对挥发性化合物进行鉴定,寻找具有抗菌活性的生物活性化合物。其次,采用顶空固相微萃取(HS SPME)和气相色谱-质谱联用(GC-MS)技术对塔斯马尼亚种植的薰衣草蜂蜜和薰衣草精油的挥发性数据进行分析,以确定其地理和植物来源。采用肉汤微量稀释法测定了塔斯马尼亚薰衣草蜂蜜和薰衣草精油的抑菌活性,确定了最小抑菌浓度(MIC)和最小杀菌浓度(MBC)。用分光光度法测定抑菌终点,再用电镀法测定杀菌终点。本研究采用金黄色葡萄球菌、大肠杆菌和铜绿假单胞菌对甲氧西林敏感和耐药菌株。结果:薰衣草蜂蜜表现出与麦卢卡蜂蜜相似的活性,在某些细菌种类中活性略高于麦卢卡蜂蜜。薰衣草蜂蜜的mic和MBCs范围为6.25%至25% v/v,而麦卢卡蜂蜜的mic范围为12.5%至25% v/v。薰衣草蜂蜜和麦卢卡蜂蜜对铜绿假单胞菌的MIC和MBC值分别为12.5% v/v和25% v/v。对甲氧西林敏感的金黄色葡萄球菌对应值分别为6.25% v/v和12.5% v/v。蜂蜜对大肠杆菌的MIC和MBC均为12.5% v/v,对MRSA的MIC和MBC均为6.25% v/v。2.25%浓度的薰衣草精油完全抑制了金黄色葡萄球菌(包括MRSA)和大肠杆菌的生长。相同浓度对铜绿假单胞菌的生长有一定的抑制作用。使用分光光度计可以方便地读取MIC值。结论:薰衣草蜂蜜和精油可作为抗MRSA、大肠杆菌和铜绿假单胞菌等金黄色葡萄球菌感染的抗菌药物。
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引用次数: 0
Attitude of doctors regarding Breaking Bad News to patients in Iraq 医生对伊拉克病人突发坏消息的态度
Pub Date : 2022-12-26 DOI: 10.22317/imj.v6i4.1214
Ahmed Juwameer Khairo Al-khashmani, Wafaa Hamad Mohammed Al-Sabaawi, Nisreen Mohammed Ibraheem
Objectives: To assess the attitude of doctors with regard delivering bad news to patients and breaking bad news protocols. Methods: This is a cross sectional (descriptive study) done in Iraq from first of November 2020 to end of May 2021 involved 500 doctors ( periodic resident, senior resident, general practitioner and specialist doctors in different specialties ) working in different hospitals, primary health care centers and private clinics in Iraq, they are selected randomly. A self – administered questionnaire design in addition to online data collection, by using modified questionnaire and link sent to different online ways (whats app, viber, facebook, telegram ). Results: Out of 500 respondents doctors there were 329 (65.8%) females, 171 (34.2%) males. Regarding to attitude of doctors in breaking bad news 268 (53.6%) of doctors were need a structured protocol in breaking bad news and 280 (56%) doctors need training for breaking bad news. The SPIKES protocol is the most preferred protocol by doctors about (75.6%). Conclusion: High percentage of  participants doctors(63%) did not know any protocol in breaking bad news and about (43%) of them rated themselves had good ability in delivering bad news. The SPIKES protocol is the preferred protocol by doctors.
目的:了解医生在向患者传达坏消息和打破坏消息协议方面的态度。方法:这是一项从2020年11月1日至2021年5月底在伊拉克进行的横断面(描述性研究),涉及在伊拉克不同医院、初级卫生保健中心和私人诊所工作的500名医生(定期住院医生、高级住院医生、全科医生和不同专业的专科医生),他们是随机选择的。在网上收集数据的基础上,采用修改后的问卷和链接发送到不同的在线方式(what app, viber, facebook, telegram),进行自我管理问卷设计。结果:500名受访医生中,女性329人(65.8%),男性171人(34.2%)。关于医生对突发坏消息的态度,268名(53.6%)医生表示需要结构化的突发坏消息预案,280名(56%)医生表示需要突发坏消息培训。spike方案是医生最喜欢的方案(75.6%)。结论:参与调查的医生中,63%的医生不了解坏消息的处理方法,43%的医生认为自己有良好的坏消息传递能力。spike协议是医生的首选协议。
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引用次数: 0
Assessment of Anthropometric measurements of Upper and Lower Limbs among Female Students of Iranian Population 伊朗族女学生上肢和下肢人体测量的评估
Pub Date : 2022-12-26 DOI: 10.22317/imj.v6i4.1202
T. Rastegar, M. Ebrahimzade, Saba Behzadifard, A. Alikarami, F. Taghizadeh, Mehdi Alidadi, Golaleh Noorzehi
Objectives: This study aimed to measure upper and lower limb dimensions among female students of Tehran University of Medical Sciences and determine the relationship between brachial and crural indices as anthropometric indices of limbs and Body Mass Index (BMI).Methods: In this descriptive-cross-sectional study, anthropometric parameters of the upper and lower limbs were evaluated among 200 Iranian female student volunteers aged 18-38 with no physical or developmental deformity.Results: The collected data were analyzed by GraphPad Prism software. Pearson correlation and simple linear regression tests were used to find the relationship between measured anthropometric indices. Mean± Standard deviation (SD) of age and BMI were 23.65 ± 4.97 and 24.59± 4.14, respectively. The brachial and crural indices were 89.47± 9.352 and 76.37± 5.320, respectively. No statistically significant association was found between brachial and crural indices and BMI. In addition, we found a significant positive correlation between wrist dimensions and BMI. The results of the present article determined the relationship between BMI and anthropometric parameters of the upper and lower limbs.Conclusions: Our findings supported the close relationship between wrist dimension and BMI.
目的:本研究旨在测量德黑兰医科大学女学生的上肢和下肢尺寸,并确定臂部和脚部指标作为四肢人体测量指标与身体质量指数(BMI)的关系。方法:在这项描述性横断面研究中,对200名年龄在18-38岁、无身体或发育畸形的伊朗女学生志愿者进行了上肢和下肢的人体测量参数评估。结果:采用GraphPad Prism软件对采集的数据进行分析。使用Pearson相关和简单线性回归检验来确定测量的人体测量指标之间的关系。年龄和BMI的均值±标准差(SD)分别为23.65±4.97和24.59±4.14。肱指数为89.47±9.352,脚指数为76.37±5.320。肱和脚指数与BMI之间无统计学意义的关联。此外,我们发现腕部尺寸与BMI之间存在显著的正相关。本文的结果确定了BMI与上肢和下肢人体测量参数之间的关系。结论:我们的研究结果支持腕部尺寸与BMI之间的密切关系。
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引用次数: 0
Frontiers in early detection of hepatocellular carcinoma 肝细胞癌早期检测的前沿
Pub Date : 2022-12-26 DOI: 10.22317/imj.v6i4.1206
Nabil Mohie Abdel-Hamid, L. Abd Almunim Baker, L. Farhan Bdaiwi
Description of the article   The need for more precise serodiagnosis marker for hepatocellular carcinoma (HCC) is always a must for many reasons: Serodiagnosis is generally non-invasive and safe technique to have a human sample. Different radiological modalities, although its accuracy is progressing, but many times its result is misinterpreted. The current extensively used seromarker, alpha fetoprotein (AFP), doesn’t exceed 70% for sensitivity and 90% for specificity. Many of clinicians requesting AFP tests, whether in HCC management or related diseases, as, hepatitis C or B infections don’t know exactly the diagnostic accuracy levels of AFP. The need for spectrophotometric marker, rather than molecular or radio or Elisa parameter as a cost effective goal. The earlier the detection of HCC, the longer the patient life.
由于多种原因,对肝细胞癌(HCC)更精确的血清诊断标志物的需求一直是必须的:血清诊断通常是非侵入性的,并且具有人体样本的安全技术。不同的放射方式,虽然其准确性在进步,但很多时候其结果被误解。目前广泛使用的血清标志物,甲胎蛋白(AFP),其敏感性不超过70%,特异性不超过90%。许多要求AFP检测的临床医生,无论是HCC治疗还是相关疾病,如丙型肝炎或乙型肝炎感染,都不知道AFP诊断的准确水平。需要分光光度标记,而不是分子或无线电或Elisa参数作为成本效益的目标。肝细胞癌越早发现,患者寿命越长。
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引用次数: 0
Assessment of serum uric acid level in patients with systemic arterial hypertension 全身性动脉高血压患者血清尿酸水平的评估
Pub Date : 2022-12-26 DOI: 10.22317/imj.v6i4.1212
Mohammed Abdul-Wahhab Abdul-Razzaq, Mohammed Abed Abu Saiba, Najah R Hadi
Objectives: To study the association between elevated serum uric acid and systemic arterial hypertension. Methods: This study is a case-control study conducted in Al-Sadr Teaching City / Al-Najaf city from December 2019 till the end of February 2020, and included (69) cases diagnosed with systemic arterial hypertension and (71) non- hypertensive. All participants underwent anthropometric measurements and laboratory investigations for serum uric acid level, total cholesterol, high-density lipoprotein level, triglyceride level, serum blood urea and serum creatinine. Results: The study enrolled a total of (140) participants whose mean age was (47.21 ± 12.53) years. Males comprised (57.14%) of total study sample. Serum uric acid level was found to be significantly higher among hypertensive compared to non-hypertensive, P-value = 0.003. Hyperuricemia was found to be significantly correlated with hypertension, with P-value of 0.017, Odds ratio = 9.18 (95% C.I.: 1.12 – 75.50). Conclusions: Serum uric acid level is significantly higher in hypertensive group compared to non-hypertensive group, with the presence of significant numbers with hyperuricemia among hypertensive patients.  
目的:探讨血尿酸升高与全身性动脉高血压的关系。方法:本研究是一项病例对照研究,于2019年12月至2020年2月底在Al-Sadr教学城/ Al-Najaf市进行,其中包括(69)例诊断为全身性动脉高血压和(71)例非高血压。所有参与者都进行了人体测量和实验室调查,包括血清尿酸水平、总胆固醇、高密度脂蛋白水平、甘油三酯水平、血清尿素和血清肌酐。结果:研究共纳入(140)名参与者,平均年龄为(47.21±12.53)岁。男性占总研究样本的57.14%。高血压患者血清尿酸水平明显高于非高血压患者,p值= 0.003。高尿酸血症与高血压显著相关,p值为0.017,优势比为9.18 (95% ci: 1.12 ~ 75.50)。结论:高血压组血清尿酸水平明显高于非高血压组,高血压患者中存在大量高尿酸血症。
{"title":"Assessment of serum uric acid level in patients with systemic arterial hypertension","authors":"Mohammed Abdul-Wahhab Abdul-Razzaq, Mohammed Abed Abu Saiba, Najah R Hadi","doi":"10.22317/imj.v6i4.1212","DOIUrl":"https://doi.org/10.22317/imj.v6i4.1212","url":null,"abstract":"Objectives: To study the association between elevated serum uric acid and systemic arterial hypertension. \u0000Methods: This study is a case-control study conducted in Al-Sadr Teaching City / Al-Najaf city from December 2019 till the end of February 2020, and included (69) cases diagnosed with systemic arterial hypertension and (71) non- hypertensive. All participants underwent anthropometric measurements and laboratory investigations for serum uric acid level, total cholesterol, high-density lipoprotein level, triglyceride level, serum blood urea and serum creatinine. \u0000Results: The study enrolled a total of (140) participants whose mean age was (47.21 ± 12.53) years. Males comprised (57.14%) of total study sample. Serum uric acid level was found to be significantly higher among hypertensive compared to non-hypertensive, P-value = 0.003. Hyperuricemia was found to be significantly correlated with hypertension, with P-value of 0.017, Odds ratio = 9.18 (95% C.I.: 1.12 – 75.50). \u0000Conclusions: Serum uric acid level is significantly higher in hypertensive group compared to non-hypertensive group, with the presence of significant numbers with hyperuricemia among hypertensive patients. \u0000 ","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89644746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge, Attitude and Practice toward COVID‐19 among Iraqi Adults in Karbala 卡尔巴拉地区伊拉克成年人对COVID - 19的知识、态度和行为
Pub Date : 2022-12-26 DOI: 10.22317/imj.v6i4.1208
S. I. Al-Ghabban
Objectives: to assess the knowledge, attitude and practice scores regarding COVID-19 in relation to sociodemographic states among the Iraqi adults in Karbala, Methods: This cross-sectional population based interview survey involved 425 Iraqi adult population in Karbala, Iraq between December 2021 and February 2022 using a cluster sampling technique. Closed-ended questionnaire regarding the sociodemographic variables and questions about the knowledge, attitude and practice towards COVD-19. The data were analysed using SPSS software (version 25). The mean scores were calculated, and Independent-samples t test, one-way analysis of variance (ANOVA), or Chi-square test (X2) were used to test for differences. Results: The mean knowledge, attitude, and practice scores were 80.67%, 54.35%, and 50.83% % of total achievable scores respectively. Females showed significantly higher knowledge attitude, and practice mean scores than males. Higher mean score of attitude was found among 18-25 years of age among those with bachelor’s degree. The unmarried showed higher scores of attitude, and practice than married. Students showed higher attitude score than other occupational groups. Conclusion: Karbala adult population have high knowledge, negative attitude and weak practice in the precautionary measures about COVID-19, with an uneven distribution of behavioral patterns among socio-demographic subgroups. Further research targeting the vulnerable people is recommended so that the health education and communication interventions be ensured according to their needs.
目的:评估卡尔巴拉伊拉克成年人与社会人口统计状态有关的COVID-19知识、态度和实践得分。方法:采用整群抽样技术,在2021年12月至2022年2月期间对伊拉克卡尔巴拉的425名伊拉克成年人进行了横断面人口访谈调查。关于社会人口学变量和对covid -19的知识、态度和做法的封闭式问卷。采用SPSS软件(25版)对数据进行分析。计算平均得分,采用独立样本t检验、单因素方差分析(ANOVA)或卡方检验(X2)进行差异检验。结果:知识、态度和实践得分分别占总分的80.67%、54.35%和50.83%。女性的知识态度、实践均分显著高于男性。在18-25岁的本科学历人群中,态度的平均分较高。未婚者的态度和行为得分高于已婚者。学生的态度得分高于其他职业群体。结论:卡尔巴拉市成年人群对COVID-19预防措施的认知度高,态度消极,实践薄弱,行为模式在社会人口亚组间分布不均匀。建议针对弱势群体进行进一步研究,以便根据他们的需要确保健康教育和交流干预措施。
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引用次数: 1
Septoplasty with Nasal Packing or Transseptal Suturing: comparative study 鼻中隔填塞与经鼻中隔缝合成形术的比较研究
Pub Date : 2022-12-26 DOI: 10.22317/imj.v6i4.1207
Usama Zidan Khalaf, Raad Darweesh Fadhil Ghadeer, Mohammed Abdulwahab Bahjat
Objective: The aim of study is to find out the better option to manage post-operative septal hematoma between the nasal packing or quilting sutures. Methods: cross sectional comparative study of 2 groups patients, group [A]; 39 patients have septoplasty with no nasal Packing and suturing, while group [B]; 40 patients have septoplasty with nasal packing. The study has been carried out from July 2021 until February 2022 in Kirkuk General Hospital. From all patients take age, gender, pain, and bleeding occurrence after few moments after surgery, then after 1st day and then after seventh day after operation. Also, if patients have synechiae or not. Results: there is significant difference between group A and group B in bleeding at time of operation, group A patient more bleeding. There is significant difference between group A and group B in bleeding at 1st day after operation, group A patient less bleeding. There is significant difference between group A and group B in pain at 1st day after operation, group A patient less bleeding. There is significant difference between group A and group B in pain at 7th day after operation, group A patient less bleeding. Conclusion:  Nasal pain, headache, were reduced in the trans – septal suturing group as compared to packing. However, nasal bleeding was present in both the groups. It also proves to be a cost-effective modality and gives a better post-operative quality of life to patients. Hence, we recommend trans-septal suturing as the preferred method over anterior nasal packing in patients after septoplasty.
目的:探讨术后鼻中隔血肿的处理方法。方法:两组患者横断面比较研究,A组;39例患者行鼻中隔成形术,无鼻腔填塞缝合,对照组[B];40例患者采用鼻腔填塞鼻中隔成形术。该研究于2021年7月至2022年2月在基尔库克总医院进行。所有患者术后数分钟、术后第1天、术后第7天分别记录年龄、性别、疼痛、出血情况。还有,病人是否有粘连。结果:A组与B组术中出血量比较差异有统计学意义,A组出血量较多。A组与B组术后第1天出血比较差异有统计学意义,A组患者出血较少。A组与B组术后第1天疼痛程度差异有统计学意义,A组患者出血较少。术后第7天疼痛程度A组与B组比较差异有统计学意义,A组患者出血较少。结论:鼻中隔缝合组鼻痛、头痛较填塞组明显减轻。然而,两组患者均出现鼻出血。它也被证明是一种具有成本效益的方式,并为患者提供了更好的术后生活质量。因此,我们推荐经鼻中隔缝合作为鼻中隔成形术后患者的首选方法。
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引用次数: 0
Investigation the role of some biochemical variables in liver Cirrhosis 探讨一些生化指标在肝硬化中的作用
Pub Date : 2022-12-26 DOI: 10.22317/imj.v6i4.1187
Hemn Jameel Majeed, P. Ismail, Lutfia Muhammad Hassan
Objectives: The current study is to assess nitric oxide levels as well as a few other biochemical parameters in individuals with hepatic Cirrhosis disease.Methods: The study included 55 age-matched controls and 57 individuals with cirrhosis disease that were both clinically and biochemically identified. Adenosine deaminase (ADA), albumin, aspartate tansaminase (AST), alanine transaminase (ALT), -glutamyl transpeptidase (GGT), and alkaline phosphatase were measured as part of the biochemical analyses (ALP).Results: The study group's serum nitric oxide (NO) levels were substantially (p 0.001) greater than those of the control group's. Additionally, the results showed that the activities of the enzymes ADA, GGT, ALP, AST, and ALT were significantly higher in liver cirrhotic patients than in the control group.Conclusions: Nitric oxide concentration elevation may serve as a potential diagnostic indicator for liver cirrhosis.
目的:目前的研究是评估肝硬化患者的一氧化氮水平以及其他一些生化参数。方法:该研究包括55名年龄匹配的对照组和57名临床和生化鉴定的肝硬化患者。测定腺苷脱氨酶(ADA)、白蛋白、天冬氨酸转氨酶(AST)、丙氨酸转氨酶(ALT)、-谷氨酰转肽酶(GGT)和碱性磷酸酶作为生化分析(ALP)的一部分。结果:研究组血清一氧化氮(NO)水平显著高于对照组(p < 0.001)。此外,结果显示肝硬化患者ADA、GGT、ALP、AST和ALT酶活性显著高于对照组。结论:一氧化氮浓度升高可作为肝硬化的潜在诊断指标。
{"title":"Investigation the role of some biochemical variables in liver Cirrhosis","authors":"Hemn Jameel Majeed, P. Ismail, Lutfia Muhammad Hassan","doi":"10.22317/imj.v6i4.1187","DOIUrl":"https://doi.org/10.22317/imj.v6i4.1187","url":null,"abstract":"Objectives: The current study is to assess nitric oxide levels as well as a few other biochemical parameters in individuals with hepatic Cirrhosis disease.\u0000Methods: The study included 55 age-matched controls and 57 individuals with cirrhosis disease that were both clinically and biochemically identified. Adenosine deaminase (ADA), albumin, aspartate tansaminase (AST), alanine transaminase (ALT), -glutamyl transpeptidase (GGT), and alkaline phosphatase were measured as part of the biochemical analyses (ALP).\u0000Results: The study group's serum nitric oxide (NO) levels were substantially (p 0.001) greater than those of the control group's. Additionally, the results showed that the activities of the enzymes ADA, GGT, ALP, AST, and ALT were significantly higher in liver cirrhotic patients than in the control group.\u0000Conclusions: Nitric oxide concentration elevation may serve as a potential diagnostic indicator for liver cirrhosis.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87550846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Platelet rich plasma and exercise for pain relief in end stage knee osteoarthritis 富血小板血浆和运动缓解终末期膝关节骨关节炎的疼痛
Pub Date : 2022-12-26 DOI: 10.22317/imj.v6i4.1211
Abdullah Ahmed Mohammad, Hayder Ghali Wadi Algawwam, Huda Ihsan KhairuAllah, Nuha Abdulwahab Muhammed Ali, Safwat Abbas Ali
Objective: To evaluate the efficacy of exercise and intra-articular ozonized platelet rich plasma (IA-OPRP) injections as management for sever grad IV knee osteoarthritis (KOA). Methods: Over 18-month period (January 1, 2018– July 31, 2019), 33 patients (21 females and 12 males) with 58 grade IV osteoarthritic knees were retrospectively studied. Severity of KOA was assessed according to the clinical features and Kellgren &Lawrencegrading scale. All patients underwent 8-weeks simple exercises followed by 4 sessions of IA-OPRP.OPRP was prepared by centrifuging patients’ own blood and activated by passing 1 ml of ozone for each 1 ml of platelet rich plasma. A questionnaire was used to categorize the pain severity into mild, moderate, and severe and the response to therapy was graded as excellent, good, fair, and poor. Results: The mean age was 63.7 years. The top co-morbid condition were overweight and obesity (n=28, 84.8%) whereas diabetes and hypertension ranked second (n=15 each, 45.4%). All patients had severe pain of grad IV knee OA. Overall, exercise and four IA-OPRP injections yielded good-excellent results in (72.4%) of the treated joints (p˂0.01) with no significant sex-related difference in pain response (p>0.01). Conclusion: Exercise and IA-OPRP seems to be a safe, effective and cheap method for relieving the chronic pain of severeknee OA.
目的:评价运动联合关节内臭氧富血小板血浆(IA-OPRP)注射治疗严重IV级膝关节骨性关节炎(KOA)的疗效。方法:回顾性分析2018年1月1日至2019年7月31日18个月期间,33例(女性21例,男性12例)膝关节IV级骨关节炎58例。根据临床特征和Kellgren & lawrence分级量表评估KOA的严重程度。所有患者都进行了8周的简单运动,随后进行了4次IA-OPRP。OPRP采用患者自身血液离心制备,每1ml富血小板血浆通过1ml臭氧活化。使用问卷将疼痛严重程度分为轻度、中度和重度,对治疗的反应分为极好、良好、一般和差。结果:患者平均年龄63.7岁。其中,体重超重和肥胖占首位(n=28,占84.8%),糖尿病和高血压占第二位(n=15,占45.4%)。所有患者均有严重的IV级膝关节炎疼痛。总的来说,运动和四次IA-OPRP注射在治疗关节中获得了良好的效果(72.4%)(p小于0.01),疼痛反应无显著的性别差异(p小于0.01)。结论:运动联合IA-OPRP是一种安全、有效、廉价的缓解重度膝关节炎慢性疼痛的方法。
{"title":"Platelet rich plasma and exercise for pain relief in end stage knee osteoarthritis","authors":"Abdullah Ahmed Mohammad, Hayder Ghali Wadi Algawwam, Huda Ihsan KhairuAllah, Nuha Abdulwahab Muhammed Ali, Safwat Abbas Ali","doi":"10.22317/imj.v6i4.1211","DOIUrl":"https://doi.org/10.22317/imj.v6i4.1211","url":null,"abstract":"Objective: To evaluate the efficacy of exercise and intra-articular ozonized platelet rich plasma (IA-OPRP) injections as management for sever grad IV knee osteoarthritis (KOA). \u0000Methods: Over 18-month period (January 1, 2018– July 31, 2019), 33 patients (21 females and 12 males) with 58 grade IV osteoarthritic knees were retrospectively studied. Severity of KOA was assessed according to the clinical features and Kellgren &Lawrencegrading scale. All patients underwent 8-weeks simple exercises followed by 4 sessions of IA-OPRP.OPRP was prepared by centrifuging patients’ own blood and activated by passing 1 ml of ozone for each 1 ml of platelet rich plasma. A questionnaire was used to categorize the pain severity into mild, moderate, and severe and the response to therapy was graded as excellent, good, fair, and poor. \u0000Results: The mean age was 63.7 years. The top co-morbid condition were overweight and obesity (n=28, 84.8%) whereas diabetes and hypertension ranked second (n=15 each, 45.4%). All patients had severe pain of grad IV knee OA. Overall, exercise and four IA-OPRP injections yielded good-excellent results in (72.4%) of the treated joints (p˂0.01) with no significant sex-related difference in pain response (p>0.01). \u0000Conclusion: Exercise and IA-OPRP seems to be a safe, effective and cheap method for relieving the chronic pain of severeknee OA.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80362074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Iraq Medical Journal
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