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Effects of Smoking on Serum Ferritin levels in adult population living in Sulaymaniyah, Iraq: A Retrospective Cross-sectional Study 吸烟对伊拉克苏莱曼尼亚成年人血清铁蛋白水平的影响:一项回顾性横断面研究
Pub Date : 2023-06-26 DOI: 10.22317/imj.v7i2.1238
J. Hadi, Shanya B. Shawkat, Hwda Gh. Rauf, Soma A. Hama Karim, Ayman M. Mustafa, Soz N. Muhammad, Mhamad S. Abdullah
Objectives: The current study aims to examines the effect of smoking on serum ferritin levels of adult populations in Sulaymaniyah.  Methods: The study was conducted on 80 smokers and 20 non-smokers, totally 100 persons. Their ages ranged from 18 to 65 years. Results: This study showed that the majority of smokers had elevated ferritin levels. A p-value of less than 0.05 indicated a significant difference in ferritin levels between smokers and non-smokers groups. The average ferritin level among smoker group was 227.40 mg/L, while the average ferritin level among non-smokers group was 118.3 mg/L. Regarding the associated between age groups and average ferritin levels, the average ferritin level is highest in the age groups between 51-61 years old. In addition, obesity may play a role in raising ferritin levels, people with obese conditions (BMI > 30) have the highest average ferritin levels than others. Conclusion: This study provides evidence that smoking negatively affect serum ferritin levels, since increases in mean ferritin levels are very striking in smoking and obese group.
目的:本研究旨在探讨吸烟对苏莱曼尼亚成年人群血清铁蛋白水平的影响。方法:选取吸烟者80例,非吸烟者20例,共100例。他们的年龄从18岁到65岁不等。结果:本研究表明,大多数吸烟者的铁蛋白水平升高。p值小于0.05表明吸烟者和非吸烟者之间铁蛋白水平有显著差异。吸烟组平均铁蛋白水平为227.40 mg/L,非吸烟组平均铁蛋白水平为118.3 mg/L。关于年龄与平均铁蛋白水平的关系,平均铁蛋白水平在51-61岁年龄组中最高。此外,肥胖可能在铁蛋白水平升高中起作用,肥胖人群(BMI > 30)的平均铁蛋白水平高于其他人。结论:本研究提供了吸烟对血清铁蛋白水平有负面影响的证据,因为吸烟和肥胖组的平均铁蛋白水平升高非常显著。
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引用次数: 0
Comparative Study of Quantitative Real-Time Monitoring QRT-PCR for BCR-ABL Gene in Chronic Myelogenous Leukemia (CML) Between Blood and Bone Marrow Samples 慢性粒细胞白血病(CML)血液与骨髓BCR-ABL基因定量实时监测QRT-PCR的比较研究
Pub Date : 2023-06-26 DOI: 10.22317/imj.v7i2.1215
Azhar Haleem, Rana Al-Ani, Ghada Burhan
Objectives: This study aimed to assess the quantitative real-time RT-PCR (QRT-PCR) technique as a diagnostic tool for molecular surveillance of the BCR-ABL duplicate in Chronic Myelogenous Leukemia (CML) using both peripheral blood (PB) and bone marrow (BM) samples. Methods: Prospective analysis has been conducted a by quantitative real-time RT-PCR (QRT-PCR) for both PB and BM specimens, from 25 patients with untreated CML. QRT-PCR investigation was carried out previous and during treatment with Imatinib for untreated CML. Statistical examinations showed useful agreement of PB and BM pre- treatment specimens. Nevertheless, using the SPSS statistical method that estimates the agreement between PB and BM data, Results: This study showed low correspond of BCR-ABL measurements in PB and BM for specimens acquired through treatment. PB values tended to be lower than the conformable BM values [average difference = -0.37 (p<0.001) in 36 coupled samples] and the 95% limits of agreement ranged from -1.23 to 0.48. Nevertheless, the present study showed that BM and PB QRT-PCR values followed a similar direction during treatment (Spearman correlation coefficient, 0.83; 95% CI, 0.70, 0.96). Conclusion: Our findings imply that PB and BM measures of BCR-ABL are frequently quantitatively different. The most accurate way to determine whether there is minimal residual disease is through BM sampling because BM results tend to be greater than PB values (MRD). Based on these findings, we advise avoiding switching BM and PB sampling for MRD monitoring during CML treatment because doing so could result in incorrect interpretation of treatment outcomes.
目的:本研究旨在评估实时定量RT-PCR (QRT-PCR)技术作为慢性髓性白血病(CML)外周血(PB)和骨髓(BM)样本中BCR-ABL重复分子监测的诊断工具。方法:采用定量实时RT-PCR (QRT-PCR)对25例未经治疗的CML患者的PB和BM标本进行前瞻性分析。对未经治疗的CML进行伊马替尼治疗前和治疗期间的QRT-PCR调查。统计检验显示PB和BM预处理标本有很好的一致性。然而,使用SPSS统计方法估计PB和BM数据之间的一致性,结果:本研究显示,通过处理获得的标本中PB和BM的BCR-ABL测量值的对应度较低。PB值倾向于低于符合的BM值[36个偶联样本的平均差值= -0.37 (p<0.001)], 95%的一致性范围为-1.23至0.48。然而,本研究显示,在治疗过程中,BM和PB QRT-PCR值遵循相似的方向(Spearman相关系数,0.83;95% ci, 0.70, 0.96)。结论:我们的研究结果表明,BCR-ABL的PB和BM测量在数量上经常不同。确定是否存在最小残留疾病的最准确方法是通过BM取样,因为BM结果往往大于PB值(MRD)。基于这些发现,我们建议在CML治疗期间避免将BM和PB采样转换为MRD监测,因为这样做可能导致对治疗结果的错误解释。
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引用次数: 0
Epidemiological Investigation of Neonatal Jaundice in Tikrit City: Assessing Neonatal Risk Factors from 2022 to 2023 提克里特市新生儿黄疸流行病学调查:评估2022 - 2023年新生儿危险因素
Pub Date : 2023-06-26 DOI: 10.22317/imj.v7i2.1241
Firdous Salih M. Al-Jiboury, A. Salman, A. R. Sarhat
Objectives:  This study aimed to assess the prevalence of neonatal jaundice and explore associated risk factors in Tikrit City, Iraq.   Methods: The current study was  a cross sectional study involved 312 neonates (204 of them with jaundice and 108 without jaundice ), attending Salahaddin General hospital from 1st October 2022 to 30th January 2023. The Study sample was convenient . Jaundiced and Non-jaundiced neonates were enrolled into the study when they enter the wards of pediatrics and neonatal intensive care unites in  Salahaddin General Hospital and those visits outpatient clinics of pediatricians and the general population during a free neonatal jaundice screening campaign in Tikrit City. Results: The prevalence of neonatal jaundice is (9.2%). The most frequent cases was having total serum bilirubin(TSB) level ≤18 milligram/dc liter(mgdl) (84.8%).The mean ±standard deviation (SD) of hyperbilirubinemia level is (15 ± 3.366 mgdl ) and  the high TSB level was reported among male gender(58.3%).The percent of preterm babies   was (33.3%) of total sample .The most cases had normal weight (66.7%) at time of delivery ,mean ±SD  of weight is (2698.5±693.54gram) and had no bruises or hematoma as cephalohematoma (89.2%).There was no blood diseases in about (72.5%) of total sample and no history of infection in (68.1%) of cases. The most frequent methods of feeding was breast feeding (39.7%). Regarding to time of appearance of jaundice, the most frequent cases were among those with age group (≤5 days )(89.7%) .The mean±SD  for age of neonate at time of admission is (6.2±3.6 day). Blood group incompatibility(ABO  incompatibility) was found in (60.8%) of cases with TSB level ≤18 mg/dl and (11.3%) of cases of TSB level <18 mgdl . While Rhesus incompatibility(Rh incompatibility) was found in (13.2%) of cases with TSB level ≤18 mg/dl . Conclusion: This study highlights a prevalence of 9.2% for neonatal jaundice in Tikrit City and identifies important risk factors such as blood group incompatibility and preterm birth. Early detection and appropriate management of neonatal jaundice are crucial to prevent potential complications and ensure optimal neonatal care.
目的:本研究旨在评估伊拉克提克里特市新生儿黄疸的患病率并探讨相关危险因素。方法:本研究是一项横断面研究,涉及2022年10月1日至2023年1月30日在Salahaddin总医院就诊的312名新生儿(其中有黄疸的204名,无黄疸的108名)。研究样本很方便。在提克里特市的免费新生儿黄疸筛查活动中,患有黄疸和非黄疸的新生儿在进入萨拉哈丁总医院儿科病房和新生儿重症监护病房,以及访问儿科医生门诊诊所和普通人群时被纳入研究。结果:新生儿黄疸患病率为9.2%。以血清总胆红素(TSB)水平≤18毫克/dc升(mgdl)最为常见(84.8%)。高胆红素血症的平均±标准差(SD)为(15±3.366 mgdl), TSB在男性中较高(58.3%)。早产儿占总产儿的33.3%,分娩时体重正常(66.7%),体重平均±标准差(2698.5±693.54g),无瘀伤、血肿(89.2%)。约72.5%的病例无血液病,68.1%的病例无感染史。最常见的喂养方式是母乳喂养(39.7%)。在黄疸出现的时间上,以年龄≤5天的患儿最为常见(89.7%),入院时新生儿年龄的平均值±SD为(6.2±3.6天)。TSB水平≤18 mg/dl的患者(60.8%)和<18 mg/dl的患者(11.3%)存在血型不相容(ABO不相容)。而TSB水平≤18 mg/dl的病例(13.2%)存在恒河猴不相容(Rh不相容)。结论:该研究突出了提克里特市9.2%的新生儿黄疸患病率,并确定了血型不合和早产等重要危险因素。新生儿黄疸的早期发现和适当管理对于预防潜在并发症和确保最佳新生儿护理至关重要。
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引用次数: 0
Epidemiological and clinical aspects of congenital heart disease in Fallujah Maternity and Children Hospital, Iraq 伊拉克费卢杰妇幼医院先天性心脏病的流行病学和临床方面
Pub Date : 2023-06-26 DOI: 10.22317/imj.v7i2.1240
S. Alaani, Firas Sadiq Alkubaisy, Abdulqadir Abdulkareem Merie
Objective: This study aimed to analyze the descriptive characteristics of children diagnosed with Congenital Heart Disease (CHD) at Fallujah Maternity and Children Hospital (FMCH). Methods: The prospective study included 1,025 pediatric patients born between 1st December 2018 and 30th September 2022, admitted to the newborns and children's wards, and diagnosed with CHD. Data were collected through interviews with patients' guardians using a registration and questionnaire form, capturing variables related to the child (e.g., name, sex, birth weight, type of CHD) and the mother (e.g., age, occupation, consanguinity, previous CHD births, chronic diseases during pregnancy). Residence (rural or urban) was also recorded. Results: Among the CHD cases, Atrial Septal Defect (ASD) was the most common (72%), followed by Ventricular Septal Defect (VSD) (25%) and Patent Ductus Arteriosus (PDA) (21%). Most diagnoses occurred in children aged 1-28 days. The male-to-female ratio was 1.2:1, and 0.2% had an ambiguous gender. About 58% of children weighed ≥ 2.5kg at birth, and 20% had a family history of CHDs. Conclusion: The increasing prevalence of congenital heart diseases in Fallujah requires preventive strategies targeting modifiable risk factors, better monitoring of high-risk pregnancies, and increased awareness of genetic counseling for families with congenital anomalies. The cardiology department should receive more attention and resources to improve diagnostic and therapeutic capabilities. Further research is needed to understand the reasons behind the recent rise in CHD cases in newborns.
目的:本研究旨在分析在费卢杰妇幼医院(FMCH)诊断为先天性心脏病(CHD)儿童的描述性特征。方法:前瞻性研究纳入1025名于2018年12月1日至2022年9月30日出生、在新生儿和儿童病房就诊、诊断为冠心病的儿童患者。通过与患者监护人的访谈收集数据,采用登记和问卷形式,获取与儿童(如姓名、性别、出生体重、冠心病类型)和母亲(如年龄、职业、血缘关系、以前的冠心病出生、怀孕期间的慢性病)相关的变量。居住地(农村或城市)也被记录下来。结果:冠心病患者中以房间隔缺损(ASD)最为常见(72%),其次为室间隔缺损(VSD)(25%)和动脉导管未闭(PDA)(21%)。大多数诊断发生在1-28天的儿童。男女比例为1.2:1,0.2%性别不明确。约58%的儿童出生时体重≥2.5kg, 20%有冠心病家族史。结论:费卢杰先天性心脏病患病率的上升需要针对可改变风险因素的预防策略,更好地监测高危妊娠,并提高对先天性异常家庭遗传咨询的认识。心内科应得到更多的重视和资源,以提高诊断和治疗能力。需要进一步的研究来了解最近新生儿冠心病病例上升背后的原因。
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引用次数: 0
The Level of Tumor Necrosis Factor –alpha in Patients with Acute Coronary Syndrome 急性冠脉综合征患者肿瘤坏死因子- α水平的研究
Pub Date : 2023-06-26 DOI: 10.22317/imj.v7i2.1236
Ammar Kshash Atban, Jawad Kadhim Abdullah
Objectives: This study was used to measure the level of tumor necrosis factor- alpha in patients with acute coronary syndrome. Method: A case control study was used; the level of tumor necrosis factor-alpha was measured in 39 patients with acute coronary syndrome (30male, 9female) & 20(12male, 8female) control group; risk factors (smoking, hypertension, diabetes mellitus), duration of staying in cardiac care unit & complications (recurrent angina pain, hemodynamic, electrical) are also recorded. Result: we were found significant increase in the level of tumor necrosis factor -alpha in all patients with acute coronary syndrome as compared with control group (P value< 0.01) the highest level of tumor necrosis factor -alpha are associated with myocardial infarction rather than unstable angina patients &also high rate of complications. Conclusion: According to this study tumor necrosis factor-alpha was significantly increased in acute coronary syndrome &could be used for determining severity of the diseases in patients with acute coronary syndrome.
目的:测定急性冠状动脉综合征患者的肿瘤坏死因子- α水平。方法:采用病例对照研究;测定急性冠脉综合征患者39例(男30例,女9例)和对照组20例(男12例,女8例)的肿瘤坏死因子- α水平;危险因素(吸烟、高血压、糖尿病)、住院时间和并发症(复发性心绞痛、血流动力学、电性)也被记录下来。结果:所有急性冠状动脉综合征患者的肿瘤坏死因子- α水平均较对照组显著升高(P值< 0.01),肿瘤坏死因子- α水平最高的患者与心肌梗死相关,而与不稳定型心绞痛患者相关,且并发症发生率较高。结论:急性冠脉综合征患者肿瘤坏死因子- α水平明显升高,可作为判断急性冠脉综合征患者病情严重程度的指标。
{"title":"The Level of Tumor Necrosis Factor –alpha in Patients with Acute Coronary Syndrome","authors":"Ammar Kshash Atban, Jawad Kadhim Abdullah","doi":"10.22317/imj.v7i2.1236","DOIUrl":"https://doi.org/10.22317/imj.v7i2.1236","url":null,"abstract":"Objectives: This study was used to measure the level of tumor necrosis factor- alpha in patients with acute coronary syndrome. \u0000Method: A case control study was used; the level of tumor necrosis factor-alpha was measured in 39 patients with acute coronary syndrome (30male, 9female) & 20(12male, 8female) control group; risk factors (smoking, hypertension, diabetes mellitus), duration of staying in cardiac care unit & complications (recurrent angina pain, hemodynamic, electrical) are also recorded. \u0000Result: we were found significant increase in the level of tumor necrosis factor -alpha in all patients with acute coronary syndrome as compared with control group (P value< 0.01) the highest level of tumor necrosis factor -alpha are associated with myocardial infarction rather than unstable angina patients &also high rate of complications. \u0000Conclusion: According to this study tumor necrosis factor-alpha was significantly increased in acute coronary syndrome &could be used for determining severity of the diseases in patients with acute coronary syndrome.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84586625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Checklist of Endolimax species recognized in human and animals, a review on a neglected intestinal parasitic amoeba 一种被忽视的肠内寄生变形虫的研究进展
Pub Date : 2023-06-26 DOI: 10.22317/imj.v7i2.1219
Hossein Hooshyar, M. Arbabi, P. Rostamkhani
Objectives: Endolimax is a protozoan genus belongs to Amoebida order. The member of this genus occurrence in a vast range of vertebrate and invertebrate, but the species of this genus are not well studied. This review aimed to provide an updated list and some summarized information on Endolimax species, which were identified in human and animals up to the 2023. Methods: The present study was carried out to evaluate the Endolimax species with a broad review of the literature, books and electronic databases such as ISI Web of Science, PubMed, Scopus, Science Direct and Google Scholar until 2023. The hosts, pathogenicity, synonyms and distribution of valid species were considered and recorded. Results: Totally 20 defined species of Endolimax were found. Among them, only 12 species of Endolimax have been accepted as valid species. The valid species  arranged by the host, including 1 species in human, 2 species in rodents, 1 species in birds, 2 species in reptiles, 1 species in amphibian, 4 species in arthropod and 1 species in fishes. Conclusion: Intensive studies are needed in order to identification of other new and valid species in different animals and their characteristics.
目的:内窥镜是阿米巴目原生动物属。该属的成员广泛存在于脊椎动物和无脊椎动物中,但该属的物种尚未得到很好的研究。本综述旨在提供截至2023年在人类和动物中已鉴定的Endolimax物种的更新列表和一些总结信息。方法:利用截至2023年的文献、书籍和ISI Web of Science、PubMed、Scopus、Science Direct、Google Scholar等电子数据库对Endolimax物种进行评价。考虑并记录了有效种的寄主、致病性、同义种及分布。结果:共发现已确定种20种。其中,仅有12种Endolimax被认可为有效种。宿主安排的有效种有:人1种、啮齿动物2种、鸟类1种、爬行动物2种、两栖动物1种、节肢动物4种、鱼类1种。结论:为了在不同的动物中发现新的有效种及其特征,需要深入研究。
{"title":"Checklist of Endolimax species recognized in human and animals, a review on a neglected intestinal parasitic amoeba","authors":"Hossein Hooshyar, M. Arbabi, P. Rostamkhani","doi":"10.22317/imj.v7i2.1219","DOIUrl":"https://doi.org/10.22317/imj.v7i2.1219","url":null,"abstract":"Objectives: Endolimax is a protozoan genus belongs to Amoebida order. The member of this genus occurrence in a vast range of vertebrate and invertebrate, but the species of this genus are not well studied. This review aimed to provide an updated list and some summarized information on Endolimax species, which were identified in human and animals up to the 2023. \u0000Methods: The present study was carried out to evaluate the Endolimax species with a broad review of the literature, books and electronic databases such as ISI Web of Science, PubMed, Scopus, Science Direct and Google Scholar until 2023. The hosts, pathogenicity, synonyms and distribution of valid species were considered and recorded. \u0000Results: Totally 20 defined species of Endolimax were found. Among them, only 12 species of Endolimax have been accepted as valid species. The valid species  arranged by the host, including 1 species in human, 2 species in rodents, 1 species in birds, 2 species in reptiles, 1 species in amphibian, 4 species in arthropod and 1 species in fishes. \u0000Conclusion: Intensive studies are needed in order to identification of other new and valid species in different animals and their characteristics.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87782159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute peritoneal dialysis in children (indication and complication) 儿童急性腹膜透析(指征及并发症)
Pub Date : 2023-03-26 DOI: 10.22317/imj.v7i1.1222
Ali Adnan Nabat Alajrish, A. A. Alwasity, Ahmad Adnan Nabat Alajrish
Objectives: The aim of this study was to review the Indications and complications Acute peritoneal dialysis. Method: A descriptive study was performed in pediatric central teaching hospital in Baghdad City on fifty-nine cases was admitted for peritoneal dialysis for different reasons. Results: show that the pre renal causes of PD was the most common cause which represent more than sixty percent followed by chronic renal failure and other causes, acute gastroenteritis as a cause of renal failure is most commonly seen in the first four years of life while calculi mostly seen after age of two years, sepsis is seen in the first two years of life,  Catheter blockage was the most common complication followed by bleeding and other complications, Indications for acute peritoneal dialysis in the study group uremic symptom and  oliguria was the most common indications , male to female incidence is nearly equal. Conclusion: PD was the most common cause of CKD, chronic renal failure, acute gastroenteritis, sepsis and catheter blockage was the most common complication followed by bleeding and other complications.
目的:本研究的目的是回顾急性腹膜透析的适应症和并发症。方法:对巴格达市儿科中心教学医院59例因不同原因接受腹膜透析的病例进行描述性研究。结果:表明,PD的pre肾原因最常见原因,代表超过百分之六十其次是慢性肾功能衰竭和其他原因,肾功能衰竭的急性胃肠炎的原因是第一个四年的生活中最常见的虽然结石大多见过两岁后,脓毒症是在生命的头两年,导管堵塞是最常见的并发症紧随其后出血等并发症,急性腹膜透析的适应症在研究组中以尿毒症和少尿症为最常见的适应症,男女发病率几乎相等。结论:PD是CKD最常见的病因,慢性肾衰竭、急性肠胃炎、败血症和导管堵塞是最常见的并发症,其次是出血等并发症。
{"title":"Acute peritoneal dialysis in children (indication and complication)","authors":"Ali Adnan Nabat Alajrish, A. A. Alwasity, Ahmad Adnan Nabat Alajrish","doi":"10.22317/imj.v7i1.1222","DOIUrl":"https://doi.org/10.22317/imj.v7i1.1222","url":null,"abstract":"Objectives: The aim of this study was to review the Indications and complications Acute peritoneal dialysis. \u0000Method: A descriptive study was performed in pediatric central teaching hospital in Baghdad City on fifty-nine cases was admitted for peritoneal dialysis for different reasons. \u0000Results: show that the pre renal causes of PD was the most common cause which represent more than sixty percent followed by chronic renal failure and other causes, acute gastroenteritis as a cause of renal failure is most commonly seen in the first four years of life while calculi mostly seen after age of two years, sepsis is seen in the first two years of life,  Catheter blockage was the most common complication followed by bleeding and other complications, Indications for acute peritoneal dialysis in the study group uremic symptom and  oliguria was the most common indications , male to female incidence is nearly equal. \u0000Conclusion: PD was the most common cause of CKD, chronic renal failure, acute gastroenteritis, sepsis and catheter blockage was the most common complication followed by bleeding and other complications.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83371127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sclerosing Central Mucoepidermoid Carcinoma: Rare Case Series and Review 硬化性中央黏液表皮样癌:罕见病例系列及回顾
Pub Date : 2023-03-26 DOI: 10.22317/imj.v7i1.1204
A. Haleem, R. R. Al-Ani
Introduction: The most frequent malignant tumour of the salivary glands is mucoepidermoid carcinoma which accounts for 30% of all malignancies of the salivary glands. There are numerous histologic variations with various levels of differentiation. Sclerosing MEC (SMEC) is a rare subtype of MEC that has the potential to be misdiagnosed as a low-grade non-SMEC malignancy or a benign reactive condition. There have been no cases of the extremely rare sclerosing variant of central or intraosseous MEC reported as of yet. Case reports: We present two cases of Sclerosing Central MEC, in which histologic analysis revealed relatively well-circumscribed, nonencapsulated tumours made up of dispersed epithelial islands of low-grade MEC and extensive central sclerosis. Similar sclerotic stroma was present in the tumor in the second case, but the epithelial component was of intermediate grade. Both cases showed abundant intracytoplasmic mucin and positive Mayer mucicarmine and PAS stains. Conclusions: Sclerosing central mucoepidermoid carcinoma was identified as the cause. Both cases underwent a complete resection of the tumor and have since been free of the disease.
涎腺最常见的恶性肿瘤是粘液表皮样癌,占所有涎腺恶性肿瘤的30%。有许多不同程度分化的组织学变异。硬化性MEC (SMEC)是一种罕见的MEC亚型,有可能被误诊为低级别非SMEC恶性肿瘤或良性反应性疾病。到目前为止,还没有极为罕见的中央或骨内MEC硬化变体的病例报道。病例报告:我们报告了两例硬化性中央MEC,其中组织学分析显示相对明确的,非包膜肿瘤由分散的低级别MEC上皮岛和广泛的中央硬化组成。第二例肿瘤中也有类似的硬化间质,但上皮成分为中等级别。两例均显示胞浆内黏液蛋白丰富,Mayer黏液胺和PAS染色阳性。结论:硬化性中心性黏液表皮样癌为病因。这两个病例都接受了肿瘤的完全切除,并从此摆脱了疾病。
{"title":"Sclerosing Central Mucoepidermoid Carcinoma: Rare Case Series and Review","authors":"A. Haleem, R. R. Al-Ani","doi":"10.22317/imj.v7i1.1204","DOIUrl":"https://doi.org/10.22317/imj.v7i1.1204","url":null,"abstract":"Introduction: \u0000The most frequent malignant tumour of the salivary glands is mucoepidermoid carcinoma which accounts for 30% of all malignancies of the salivary glands. There are numerous histologic variations with various levels of differentiation. Sclerosing MEC (SMEC) is a rare subtype of MEC that has the potential to be misdiagnosed as a low-grade non-SMEC malignancy or a benign reactive condition. There have been no cases of the extremely rare sclerosing variant of central or intraosseous MEC reported as of yet. \u0000Case reports: \u0000We present two cases of Sclerosing Central MEC, in which histologic analysis revealed relatively well-circumscribed, nonencapsulated tumours made up of dispersed epithelial islands of low-grade MEC and extensive central sclerosis. Similar sclerotic stroma was present in the tumor in the second case, but the epithelial component was of intermediate grade. Both cases showed abundant intracytoplasmic mucin and positive Mayer mucicarmine and PAS stains. \u0000Conclusions: \u0000Sclerosing central mucoepidermoid carcinoma was identified as the cause. Both cases underwent a complete resection of the tumor and have since been free of the disease.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87611623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical outcome of lower limbs radiculopathy “due to degenerative lumbar canal stenosis” 12-24 months after decompression 下肢神经根病“退行性腰椎管狭窄”减压后12-24个月的手术结果
Pub Date : 2023-03-26 DOI: 10.22317/imj.v7i1.1224
Nashaddin Azeez Mohammed, Ari Sami Hussain
Objectives: Interlaminar decompression is a surgical procedure that decompresses the lumbar spinal canal in order to release neuro-vascular components that have been compromised by degenerative stenosis. It can significantly improve patient quality of life and reduce morbidity and the effects of lumbar canal stenosis. Methods: A retrospective study of 57 patients, surgically operated for degenerative lumbar canal stenosis, at the Sulaymaniyah teaching hospital between Mar. 2018 and Mar. 2020. Diagnosis was achieved via history and clinical examination and radiological imaging (Lumbo-sacral spine MRI).  Surgical procedure was standardized for all patients that was interlaminar decompression of the lumbar spinal canal, the postoperative follow up was after 12-24 months. Results: In total, 57 patients with degenerative lumbar canal stenosis (due to ligamentum flavum hypertrophy) were included, male (26%) and female (74%), age of the cases were between 34 – 85 years, mean 57.39 and median 57 and standard deviation 10.96, there were no deference in the outcome of different ages and genders. chief complain of patients were back pain and both lower limbs radiculopathy in the majority of the cases, associated with paresthesia and numbness of the lower limbs, which were improved modestly after surgical decompression. Conclusion: Interlaminar decompression of the stenosed lumbar spinal canal is an effective and generally safe surgical procedure with high patient satisfaction and good functional outcomes expected.
目的:椎板间减压是一种减压腰椎管的外科手术,目的是释放因退行性狭窄而受损的神经血管成分。可显著提高患者的生活质量,减少腰椎管狭窄的发病率和影响。方法:回顾性研究2018年3月至2020年3月在苏莱曼尼亚教学医院手术治疗退行性腰椎管狭窄的57例患者。通过病史、临床检查和放射学成像(腰骶脊柱MRI)进行诊断。所有腰椎管椎板间减压患者手术程序标准化,术后随访12-24个月。结果:共纳入退行性腰椎管狭窄(黄韧带肥大所致)患者57例,男性占26%,女性占74%,年龄34 ~ 85岁,平均57.39,中位数57,标准差10.96,不同年龄、性别预后无差异。患者的主要主诉为背部疼痛和双下肢神经根病,多数病例伴有感觉异常和下肢麻木,手术减压后轻度改善。结论:腰椎管狭窄椎间减压术是一种有效且安全的手术方法,患者满意度高,功能预后良好。
{"title":"Surgical outcome of lower limbs radiculopathy “due to degenerative lumbar canal stenosis” 12-24 months after decompression","authors":"Nashaddin Azeez Mohammed, Ari Sami Hussain","doi":"10.22317/imj.v7i1.1224","DOIUrl":"https://doi.org/10.22317/imj.v7i1.1224","url":null,"abstract":"Objectives: Interlaminar decompression is a surgical procedure that decompresses the lumbar spinal canal in order to release neuro-vascular components that have been compromised by degenerative stenosis. It can significantly improve patient quality of life and reduce morbidity and the effects of lumbar canal stenosis. \u0000Methods: A retrospective study of 57 patients, surgically operated for degenerative lumbar canal stenosis, at the Sulaymaniyah teaching hospital between Mar. 2018 and Mar. 2020. \u0000Diagnosis was achieved via history and clinical examination and radiological imaging (Lumbo-sacral spine MRI).  Surgical procedure was standardized for all patients that was interlaminar decompression of the lumbar spinal canal, the postoperative follow up was after 12-24 months. \u0000Results: In total, 57 patients with degenerative lumbar canal stenosis (due to ligamentum flavum hypertrophy) were included, male (26%) and female (74%), age of the cases were between 34 – 85 years, mean 57.39 and median 57 and standard deviation 10.96, there were no deference in the outcome of different ages and genders. \u0000chief complain of patients were back pain and both lower limbs radiculopathy in the majority of the cases, associated with paresthesia and numbness of the lower limbs, which were improved modestly after surgical decompression. \u0000Conclusion: Interlaminar decompression of the stenosed lumbar spinal canal is an effective and generally safe surgical procedure with high patient satisfaction and good functional outcomes expected.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82856477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effectiveness of Ozone activated Platelet Rich Plasma intra articular injection in pain management of anterior cruciate ligament tear 臭氧活化富血小板血浆关节内注射治疗前交叉韧带撕裂疼痛的疗效观察
Pub Date : 2023-03-26 DOI: 10.22317/imj.v7i1.1226
Abdullah Ahmed Mohammad, Hayder Ghali Wadi Algawwam, Nuha Abdulwahab Muhammed Ali, Huda Ihsan KhairuAllah, Safwat Abbas Ali
Objectives: The anterior cruciate ligament (ACL) is one of the most common injured knee ligaments and it is one of the most frequent injuries seen in orthopedic practice Methods: This is a retrospective study of 20 patients (14 female and 6 male) with ACL tear managed by intra articular activated PRP injection in the first author private clinic in Kirkuk over 2 years period (August 1, 2017–July 31, 2019). A detailed history was taken according to a questionnaire and a complete physical and radiological (MRI) examination was done. A sample of patient’s own blood was used to prepare PRP by a process of two repeated centrifugation. Longevity resources EXT50 Ozone Generator with oxygen tank and CGA870 Oxygen Regulator were used for activation of PRP. The clinical notes were reviewed to ascertain the clinical presentations and response of patients to PRP therapy. Results: The mean age was 55±10.38years. The age groups affected with ACL were 50-59 and 60-69 years (n: 7, 35%) for each, while (n:5,25%) from age group 40-49 years and (n: 1, 5%) was from age group 20-29. Although 19 patient (95%) have at least one co-morbid condition, all the patient (n:20, 100%) show good response.7 patient (35%) received three doses of PRP and 13 patient (65%) received four doses to get good response. Conclusion: Even though PRP and Ozone are not expensive therapies, they seem to be safe and effective in pain management of ACL tear.
目的:前交叉韧带(ACL)是最常见的膝关节韧带损伤之一,也是骨科实践中最常见的损伤之一。方法:本研究回顾性研究了基尔库克第一作者私人诊所2年内(2017年8月1日至2019年7月31日)通过关节内活化PRP注射治疗的20例ACL撕裂患者(14名女性和6名男性)。根据问卷调查详细记录病史,并进行完整的物理和放射学(MRI)检查。取患者自身血液标本,经两次反复离心制备PRP。采用长寿资源EXT50臭氧发生器带氧气罐和CGA870氧调节器对PRP进行活化。回顾临床记录,以确定患者的临床表现和对PRP治疗的反应。结果:患者平均年龄55±10.38岁。ACL发病年龄组为50 ~ 59岁和60 ~ 69岁(n: 7.35%), 40 ~ 49岁(n: 5.25%)和20 ~ 29岁(n: 1.5%)。虽然19例患者(95%)至少有一种合并症,但所有患者(n:20, 100%)均表现出良好的反应。7例(35%)患者接受了3剂PRP治疗,13例(65%)患者接受了4剂PRP治疗。结论:虽然PRP和臭氧不是昂贵的治疗方法,但它们似乎是安全有效的治疗前交叉韧带撕裂疼痛的方法。
{"title":"The effectiveness of Ozone activated Platelet Rich Plasma intra articular injection in pain management of anterior cruciate ligament tear","authors":"Abdullah Ahmed Mohammad, Hayder Ghali Wadi Algawwam, Nuha Abdulwahab Muhammed Ali, Huda Ihsan KhairuAllah, Safwat Abbas Ali","doi":"10.22317/imj.v7i1.1226","DOIUrl":"https://doi.org/10.22317/imj.v7i1.1226","url":null,"abstract":"Objectives: The anterior cruciate ligament (ACL) is one of the most common injured knee ligaments and it is one of the most frequent injuries seen in orthopedic practice \u0000Methods: This is a retrospective study of 20 patients (14 female and 6 male) with ACL tear managed by intra articular activated PRP injection in the first author private clinic in Kirkuk over 2 years period (August 1, 2017–July 31, 2019). A detailed history was taken according to a questionnaire and a complete physical and radiological (MRI) examination was done. A sample of patient’s own blood was used to prepare PRP by a process of two repeated centrifugation. Longevity resources EXT50 Ozone Generator with oxygen tank and CGA870 Oxygen Regulator were used for activation of PRP. The clinical notes were reviewed to ascertain the clinical presentations and response of patients to PRP therapy. \u0000Results: The mean age was 55±10.38years. The age groups affected with ACL were 50-59 and 60-69 years (n: 7, 35%) for each, while (n:5,25%) from age group 40-49 years and (n: 1, 5%) was from age group 20-29. Although 19 patient (95%) have at least one co-morbid condition, all the patient (n:20, 100%) show good response.7 patient (35%) received three doses of PRP and 13 patient (65%) received four doses to get good response. \u0000Conclusion: Even though PRP and Ozone are not expensive therapies, they seem to be safe and effective in pain management of ACL tear.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86138866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Iraq Medical Journal
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