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2023 Design of Medical Devices Conference最新文献

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ROBOTIC ORTHOSIS BASED ON BEND SENSORS FOR OCCUPATIONAL MUSCULOSKELETAL DISORDER PREVENTION 基于弯曲传感器的机器人矫形器预防职业性肌肉骨骼疾病
Pub Date : 2023-04-17 DOI: 10.1115/dmd2023-1429
Jinsai Cheng, Wenbing Zhao, Tao Shen
Work-related musculoskeletal disorders are generated, preceded, or aggravated by repeated or continuous use of certain parts of the body. Orthoses have been developed to help people prevent or treat these kinds of disorders. In this paper, we developed a novel flexible orthosis based on bend sensors to count the times of the repetitive movements and remind the worker to take adequate rest after a period of repetitive movements, thus, to reduce the possibility of developing musculoskeletal disorders. A novel movement detection method is developed to count the times of the repeating movement by using the trends/slopes of the rotation angles. Experiments have been conducted to evaluate the accuracy of the novel movement detection method. The results demonstrate that the movement detection method can accurately count the times of the wrist movement with varying rotation angles and speed and issue reminders for rest.
与工作相关的肌肉骨骼疾病是由于反复或连续使用身体的某些部位而产生、发生或加重的。矫形器的开发是为了帮助人们预防或治疗这些疾病。在本文中,我们开发了一种基于弯曲传感器的新型柔性矫形器,用于计数重复运动的次数,并在一段时间的重复运动后提醒工人充分休息,从而减少发生肌肉骨骼疾病的可能性。提出了一种新的运动检测方法,利用旋转角度的趋势/斜率来计算重复运动的次数。实验验证了该方法的准确性。结果表明,该运动检测方法可以准确地统计手腕在不同旋转角度和速度下的运动次数,并发出休息提醒。
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引用次数: 0
AI BASED GLAND DETECTION IN BARRETT’S ESOPHAGUS USING OPTICAL COHERENCE TOMOGRAPHY FOR CAPSULE ENDOSCOPY DEVICE 应用光学相干断层扫描胶囊内窥镜装置检测barrett食管腺体
Pub Date : 2023-04-17 DOI: 10.1115/dmd2023-1691
Jieun Lee, Vaishnavi K. Modi, Renisha Redij, S. Gadam, K. Gopalakrishnan, Anjali Rajagopal, C. Leggett, S. P. Arunachalam
Optical coherence tomography (OCT) is an advanced imaging modality to detect Barrett’s esophagus (BE) dysplasia, providing widefield, cross-sectional imaging and microscopic resolution. BE dysplasia is characterized under OCT by the presence and number of glandular structures with atypical morphology. Accurate detection and interpretation of BE glands under OCT is essential to detect dysplastic lesions. Object Detection using deep learning has the potential to identify glands from OCT images. We developed a YOLO model to identify the presence of glands in BE tissue. The YOLOv4 object detector was trained on a custom BE dataset of 30 patients with confirmed BE who underwent OCT imaging, of which 222 OCT images included at least one gland. Our model identified glands with a high average precision of 88.79% on the test dataset. We showed that the developed model is robust to rotation, brightness, and blur in images. We have implemented an object detection model to identify glands from OCT images with promising results accurately. This model has the potential to improve the diagnosis and surveillance of BE by eliminating human error and missed dysplastic lesions adaptable for capsule endoscopy applications.
光学相干断层扫描(OCT)是一种先进的成像方式,用于检测巴雷特食管(BE)发育不良,提供宽视场,横断面成像和显微分辨率。在OCT下,BE发育不良的特征是不典型形态的腺结构的存在和数量。在OCT下准确检测和解释BE腺对于发现发育不良病变至关重要。使用深度学习的对象检测有可能从OCT图像中识别腺体。我们开发了一个YOLO模型来识别BE组织中腺体的存在。YOLOv4目标检测器在30例确诊BE患者的定制BE数据集上进行训练,这些患者接受了OCT成像,其中222张OCT图像包括至少一个腺体。我们的模型在测试数据集上识别腺体的平均精度高达88.79%。结果表明,该模型对图像的旋转、亮度和模糊具有较强的鲁棒性。我们已经实现了一个目标检测模型来准确地识别OCT图像中的腺体,结果很有希望。该模型有潜力通过消除人为错误和错过适合胶囊内窥镜应用的发育不良病变来改善BE的诊断和监测。
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引用次数: 0
CAPAPP: SMARTPHONE-BASED CAPILLARY REFILL INDEX ASSESSMENT IN HEALTHY CHILDREN Capapp:基于智能手机的健康儿童毛细血管再充盈指数评估
Pub Date : 2023-04-17 DOI: 10.1115/dmd2023-6655
Jonathan Strutt, Girish Narayanswamy, Chunjong Park, Devesh Sarda, Sixuan Wu, Matthew J. Thompson, Lauren Harvey, Rachel Hedstrom, Amy Kodet, Shwetak N. Patel, A. Mariakakis
Capillary refill time is the time it takes for blanched skin tissue under pressure to return to its normal state when that pressure is released. The test is commonly performed on the fingertip by clinicians to assess for signs of septic, traumatic, or hypovolemic shock. Current methods of capillary refill time measurement are typically subjective, coarse-grained, and clinician dependent. A more standardized and objective measurement of capillary refill time has been shown to improve the diagnosis of pediatric dehydration but has typically required specialized equipment. We have developed a digital version of the capillary refill test utilizing only a smartphone to increase access to capillary refill assessment. Our aim is to determine the accuracy and precision of this smartphone-based measure in a population of healthy pediatric subjects.
毛细血管再充盈时间是当压力释放后,处于压力下的皮肤组织恢复到正常状态所需的时间。该测试通常由临床医生在指尖进行,以评估脓毒性休克、创伤性休克或低血容量性休克的迹象。目前测量毛细血管再充盈时间的方法通常是主观的,粗粒度的,并且依赖于临床医生。一个更加标准化和客观的测量毛细血管再充血时间已被证明可以改善儿童脱水的诊断,但通常需要专门的设备。我们开发了一种数字版本的毛细血管再填充测试,仅使用智能手机来增加对毛细血管再填充评估的访问。我们的目的是确定这种基于智能手机的测量在健康儿童受试者群体中的准确性和精度。
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引用次数: 0
TOWARDS ELECTRICALLY ACTIVATING SMA-BASED COMPRESSION KNITS 朝着电激活基于sma的压缩针织的方向发展
Pub Date : 2023-04-17 DOI: 10.1115/dmd2023-3310
Alireza Golgouneh, R. Pettys-Baker, Lucy E. Dunne, B. Holschuh
Compression devices are widely used in fields such as astronautics, cosmetics, and medical therapy for treatment of various diseases such as Postural orthostatic tachycardia syndrome (POTS) and Orthostatic Hypotension (OH). Unlike traditional compression devices that apply static pressure on the body, there have been some efforts to integrate smart materials such as shape memory alloys (SMAs) to make compression garments active and controllable. SMA-based compression systems can be made in tourniquet (band) and knit (larger area) forms. SMA Knits are typically activated through direct heating approaches that may not be accessible in real-life applications. Unlike other forms of SMA actuators, due to the complexity of SMA wire interconnections in the knit, Joule heating has not been investigated yet. Hence, this paper presents an experimental protocol to electrically activate the SMA-knits through Joule heating. The designed protocol, include measurement of generated force, electrical properties, and temperature in a displacement control condition. The results of this study indicate that connecting the power leads to the middle of a knitted SMA sample along the course direction, can contribute to a better wide-reaching electrical pathway, and subsequently achieves better force generation through Joule heating.
压缩装置广泛应用于航天、化妆品、医学治疗等领域,用于体位性心动过速综合征(POTS)、体位性低血压(OH)等多种疾病的治疗。与传统的对人体施加静压的压缩装置不同,人们已经努力将形状记忆合金(sma)等智能材料集成在一起,使压缩服装具有主动性和可控性。基于sma的压缩系统可以制成止血带(带状)和编织(大面积)形式。SMA针织衫通常通过直接加热方式激活,这在实际应用中可能无法实现。与其他形式的SMA致动器不同,由于编织中SMA丝互连的复杂性,焦耳加热尚未研究。因此,本文提出了一种通过焦耳加热电激活sma织物的实验方案。设计的方案包括在位移控制条件下测量产生的力、电性能和温度。本研究结果表明,将电源导线沿过程方向连接到针织SMA样品的中间,可以提供更好的宽延伸电通路,从而通过焦耳加热实现更好的力生成。
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引用次数: 0
EXPEDITING ESOPHAGEAL MANOMETRY THROUGH CREATION OF A SLEEVE FOR A NASOGASTRIC TUBE 通过制造鼻胃管套筒加速食管测压
Pub Date : 2023-04-17 DOI: 10.1115/dmd2023-0629
H. Mansfield, Jason Shenoi, Sindhura Sridhar
Acute Respiratory Distress Syndrome (ARDS) is an acute inflammatory condition that causes impaired oxygenation and is almost always treated with mechanical ventilation. Positive End-Expiratory Pressure (PEEP) is an extrinsic pressure applied in ventilation to maintain alveolar opening. Esophageal manometry is a useful tool in titrating PEEP to ensure adequate ventilation is being provided in cases of increased chest wall pressure. However, few pulmonologists or critical care specialists utilize esophageal manometry routinely because of the required additional procedure, sparse training opportunities, and esoteric calculations required to perform the procedure and evaluate the results. We have designed, prototyped, and tested a device to simplify and reduce the time necessary to perform esophageal balloon catheterization. This device contains a balloon sleeve to be placed over a standard nasogastric tube which is capable of measuring the esophageal pressure while ventilation is being provided. Based on the esophageal pressures, a web based app created in tandem with the device calculates the desired PEEP for the ventilator settings to ensure adequate oxygenation of the patient. Statistical analysis demonstrated adequate similarities in trends compared to existing devices along with significance in pressure variability.
急性呼吸窘迫综合征(ARDS)是一种急性炎症性疾病,导致氧合受损,几乎总是用机械通气治疗。呼气末正压(PEEP)是一种在通气中施加的外部压力,以维持肺泡的开放。食管测压法是滴定PEEP的有用工具,以确保在胸壁压力增加的情况下提供足够的通气。然而,很少有肺科医生或重症监护专家经常使用食管测压术,因为需要额外的程序,培训机会稀少,以及执行程序和评估结果所需的深奥计算。我们设计、制作原型并测试了一种设备,以简化和减少执行食管球囊导管术所需的时间。该设备包含一个气球套,放置在标准鼻胃管上,在提供通气时能够测量食管压力。根据食管压力,与该设备一起创建的基于网络的应用程序计算呼吸机设置所需的PEEP,以确保患者有足够的氧合。统计分析表明,与现有设备相比,其趋势具有足够的相似性,并且在压力变异性方面具有重要意义。
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引用次数: 0
DESIGN OF BABY CUSHION FOR STROLLER USING FINITE ELEMENT SIMULATION 基于有限元仿真的婴儿车婴儿坐垫设计
Pub Date : 2023-04-17 DOI: 10.1115/dmd2023-7123
Soon-Cheol Jung, Jaemin Kim, Youngho Lee, Hyeyeong Song, Y. Kang, J. Hong
Infants spend most of the day sleeping anywhere. In the past, most parents put their infants to sleep in the prone position, but recently they put their infants to sleep in the prone position because of an issue of sudden infant death syndrome. When infants sleep in a supine position for a long time, occipital bone deformation is occurred because of pressure at the occipital region. To prevent minimize the pressure on the infant’s head and body, through the finite element simulation using the infant model, a baby cushion for the stroller was designed using the central composite design (CCD) method. The maximum contact pressure between the designed cushion and the infant model was 22.8 mmHg and this value is about 50 % lower than the pressure that occurred between the infant model and the general cushion. It can be helpful to reduce the possibility of a baby’s head deformation and other body disorders.
婴儿一天中的大部分时间都睡在任何地方。过去,大多数父母让他们的婴儿俯卧睡觉,但最近他们让他们的婴儿俯卧睡觉,因为婴儿猝死综合症的问题。婴儿长时间仰卧睡姿时,枕区受压导致枕骨变形。为了最大限度地减少对婴儿头部和身体的压力,通过婴儿模型的有限元模拟,采用中心复合设计(CCD)方法设计了一种婴儿车的婴儿坐垫。设计的缓冲垫与婴儿模型之间的最大接触压力为22.8 mmHg,该值比婴儿模型与一般缓冲垫之间的压力低约50%。它可以帮助减少婴儿头部变形和其他身体疾病的可能性。
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引用次数: 0
ANALYSES OF THE DEVICE-TISSUE INTERFACES OF PREVIOUSLY IMPLANTED STENTS WITHIN PERFUSION-FIXED HUMAN HEARTS UTIILIZING MICRO COMPUTED TOMOGRAPHY 利用微计算机断层扫描分析灌注固定人类心脏内先前植入支架的设备-组织界面
Pub Date : 2023-04-17 DOI: 10.1115/dmd2023-4061
A. DeVos, P. Iaizzo
Coronary artery disease can be caused by partial or total occlusions of the coronaries, leading to cardiac ischemia. Today, the percutaneous implantation of stents is the most common treatment to open such blockages and thus restore oxygen delivery to the myocardium. Subsequent stent calcification or restenosis may hinder the effectiveness of these stents over time. The Visible Heart® Laboratories have a collection of 30 perfusion-fixed human hearts that had a total of 35 such intervention prior to organ donation. Micro computed tomography (micro CT) can be used to study the device-tissue interfaces of stents implanted up to decades prior to recovery. These procedures were scanned with approximately 40-micron resolution. Computational models were generated such that calcification and restenosis could be visualized and quantified. Within this unique data-set, there was a wide variety of stent length, location, and volume of calcification present. Although 90% of the cases had varying degree of calcification present outside the stent only 11% showed any degree of restenosis. This is a unique research opportunity to micro CT scan 35 cases of therapeutically implanted stents in perfusion-fixed specimens. Extensive visualizations and analyses can be performed on generated computational 3D models, so to provide for better understanding of the variations within the device-tissue interfaces of therapeutically implanted stents.
冠状动脉疾病可由部分或全部冠状动脉闭塞引起,导致心脏缺血。今天,经皮支架植入是最常见的治疗方法,以打开这些阻塞,从而恢复对心肌的氧气输送。随着时间的推移,随后的支架钙化或再狭窄可能会阻碍这些支架的有效性。可见心脏®实验室收集了30个灌注固定的人类心脏,这些心脏在器官捐赠前总共进行了35次此类干预。微型计算机断层扫描(Micro computer tomography, Micro CT)可用于研究植入支架后恢复前数十年的设备-组织界面。这些程序以大约40微米的分辨率进行扫描。生成计算模型,使钙化和再狭窄可以可视化和量化。在这个独特的数据集中,存在各种各样的支架长度、位置和钙化体积。虽然90%的病例在支架外存在不同程度的钙化,但只有11%的病例表现出一定程度的再狭窄。这是一个独特的研究机会,微CT扫描35例治疗性植入支架灌注固定标本。广泛的可视化和分析可以在生成的计算3D模型上进行,以便更好地理解治疗性植入支架的设备-组织界面的变化。
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引用次数: 0
DESIGN OF FABRIC-REINFORCED POLYURETHANE COMPOSITES FOR AORTIC AND OTHER CARDIAC CONSTRUCTS 用于主动脉和其他心脏结构的纤维增强聚氨酯复合材料的设计
Pub Date : 2023-04-17 DOI: 10.1115/dmd2023-1689
Charmaine Nieves, Sandra Edward, Mayura Kulkarni, Holly M. Golecki
When patients experience heart failure, medical devices can support lost cardiac function. However, compliance mismatch between biological tissues and devices present challenges for long term integration. For example, silicone, a common polymer used in soft robotic medical devices, has negative side effects when implanted in vivo. This paper explores biomimetic properties of alternative materials by testing mechanical properties of polyurethane composites. Testing reveals similarities between our composites and native tissues in the heart and aorta. When built into fabric reinforced elastomeric enclosures (fabREEs), our composite actuators behave similar to native aortic tissue. By analyzing hoop and longitudinal stresses in actuators, we present candidate materials for building aortic models for use in transplantations or benchtop testing. We show that these materials can serve to mimic a range of cardiac tissues and that future of medical device design will benefit from considering these soft material composites in new devices.
当患者出现心力衰竭时,医疗设备可以支持失去的心脏功能。然而,生物组织和设备之间的顺应性不匹配为长期整合带来了挑战。例如,硅胶,一种用于软机器人医疗设备的常见聚合物,在体内植入时会产生负面的副作用。本文通过测试聚氨酯复合材料的力学性能,探讨替代材料的仿生性能。测试表明我们的复合材料与心脏和主动脉的天然组织有相似之处。当植入织物增强弹性体外壳(fabREEs)时,我们的复合致动器的行为与天然主动脉组织相似。通过分析执行器中的环向和纵向应力,我们提出了用于构建用于移植或台式测试的主动脉模型的候选材料。我们表明,这些材料可以用来模拟一系列心脏组织,未来的医疗设备设计将受益于在新设备中考虑这些软材料复合材料。
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引用次数: 0
SYSTEMATIC 12-CORE TRANSPERINEAL PROSTATE BIOPSY WITH MINIMAL ACTIVE NEEDLE INSERTIONS IN A PATIENT PROSTATE-SIZED PHANTOM 系统的12核经会阴前列腺活检,在患者前列腺大小的幻影中使用最小的活动针插入
Pub Date : 2023-04-17 DOI: 10.1115/dmd2023-3205
Blayton Padasdao, B. Konh
Systematic 12-core prostate biopsy has been an established practice for prostate cancer diagnosis. The procedure involves extraction of a tissue sample from 12 zones of the prostate gland for pathologic analyses using at least 12 needle insertions. The procedure is usually performed using straight needles and under ultrasound imaging. We have previously developed an active tendon-driven biopsy needle that can bend inside tissue with teleoperative or robotic control. This work presents our active biopsy needle’s capability to reach 12 marked zones in a patient-specific prostate model, avoiding the urethra, with only two insertions in a transperineal prostate biopsy.
系统的12核前列腺活检已成为前列腺癌诊断的既定做法。该过程包括从前列腺的12个区域提取组织样本进行病理分析,使用至少12针插入。该过程通常使用直针和超声成像进行。我们之前已经开发了一种主动肌腱驱动的活检针,它可以通过远程手术或机器人控制在组织内部弯曲。这项工作展示了我们的主动活检针在患者特异性前列腺模型中达到12个标记区域的能力,避免了尿道,在经会阴前列腺活检中只有两次插入。
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引用次数: 0
COUGH AUDIO SENTIMENT ANALYTICS FOR SOFTWARE AS A MEDICAL DEVICE APPLICATIONS 咳嗽音频情感分析软件作为一种医疗器械应用
Pub Date : 2023-04-17 DOI: 10.1115/dmd2023-1316
S. Damani, Arshia K. Sethi, Bhavana Baraskar, K. Gopalakrishnan, Joshika Agarwal, H. Albitar, V. Ahluwalia, S. Donlinger, V. Iyer, S. P. Arunachalam
Chronic cough is not only one of the leading causes of seeking healthcare all over the world but also a huge emotional drain on the affected patient population. In this study, we used 24-hour cough recordings to analyze the intervening conversations for sentiment analyses to better diagnose, guide, and manage treatment in such patients. We surveyed a cough clinic and selected four subjects with active cough complaints using relevant ICD-10 codes. Subjects were given and instructed to wear a device to record cough for 24 hours and the recordings were collected at weeks 0, 4, 8, and 12 of the treatment. The collected data was preprocessed to eliminate sections with no data (sleep, silence) and the number of coughs was counted. Google search API calls were used to transcribe the audio files and NLTK’s VADER analyzer was used to classify sentiments on a scale of 0 to 1. Finally, average scores were calculated and plotted over a graph to interpret any trends. 12 weeks of cough treatment had varied results on the four subjects. We categorized the exhibited sentiments into negative, neutral, positive, and compound and noted that they also showed no general trends. Among these, the compound sentiment displayed the most erratic patterns, and the obtained results could not generate a steady trend. Further studies are required with a large cohort to collect data over a longer duration to accurately analyze the sentiments associated with chronic cough.
慢性咳嗽不仅是世界各地寻求医疗保健的主要原因之一,而且也是受影响患者群体的巨大情感消耗。在这项研究中,我们使用24小时的咳嗽录音来分析干预对话,以进行情绪分析,从而更好地诊断、指导和管理这类患者的治疗。我们调查了一家咳嗽诊所,并使用相关ICD-10代码选择了4名主动咳嗽主诉的受试者。受试者被要求佩戴一个记录咳嗽24小时的设备,并在治疗的第0、4、8和12周收集记录。对采集到的数据进行预处理,剔除无数据的部分(睡眠、沉默),统计咳嗽次数。谷歌搜索API调用被用来转录音频文件,NLTK的VADER分析器被用来按0到1的等级对情绪进行分类。最后,计算平均分数并绘制在图表上,以解释任何趋势。12周的咳嗽治疗对四名受试者有不同的结果。我们将表现出的情绪分为消极、中性、积极和复合,并注意到它们也没有显示出总体趋势。其中,复合情绪表现出最不稳定的模式,所获得的结果不能产生稳定的趋势。需要进行进一步的研究,在更长的时间内收集数据,以准确分析与慢性咳嗽相关的情绪。
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引用次数: 0
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2023 Design of Medical Devices Conference
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