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Repeated laparoscopic liver resection using ICG fluorescent imaging for recurrent liver cancer 反复腹腔镜肝切除术应用ICG荧光显像诊断复发性肝癌
Q3 Medicine Pub Date : 2022-03-01 DOI: 10.1016/j.lers.2021.12.002
Zheyong Li, Jingwei Cai, Junhao Zheng, Xiao Liang

Objective

Liver cancer is very common in China, with cumulative five-year tumor recurrence rate after a microscopically margin-negative resection of hepatocellular carcinoma up to 70%. Postoperative recurrent hepatocellular carcinoma presents a challenge for surgeons because of the complexity of postoperative adhesion and the difficulty in of recognizing recurrent lesions. This study aims to introduce a method using an indocyanine green (ICG) fluorescent imaging technique to do repeated laparoscopic liver resection.

Method

Patients received repeated laparoscopic liver resection using ICG fluorescent imaging between January 2017 and December 2019 in the Department of General Surgery of Sir Run Run Shaw Hospital were analyzed retrospectively. Basic information, intraoperative information, complications, and follow-up time were collected and analyzed.

Results

Totally, 35 patients with a median age of 59 years (ranged 38–82 years) were included. All of the patients received minimally invasive surgery. One case was performed robotically, and only two cases were converted to open surgery due to severe adhesion. The median operating time was 174 minutes, and the median blood loss during surgery was 100 mL. The median hospital stay after surgery was 5 days, with a range of 3–55 days. In total, 32 (91.4%) patients showed staining by ICG fluorescent imaging, and lesions were visible on fluorescent camera. The median follow-up time was 19.7 months, with a range of 1–40.2 months. The median relapse-free survival time was 18.5 months.

Conclusion

Repeated laparoscopic liver resection using ICG fluorescent imaging is a safe and promising approach in the treatment of recurrent liver tumors in selected patients.

目的肝癌在中国非常常见,肝细胞癌显微边缘阴性切除后5年累计复发率高达70%。肝细胞癌术后复发是外科医生面临的一个挑战,因为术后粘连的复杂性和复发病变的识别困难。本研究旨在介绍一种利用吲哚菁绿(ICG)荧光成像技术进行腹腔镜肝脏重复切除术的方法。方法回顾性分析邵逸夫医院普外科2017年1月至2019年12月行反复腹腔镜肝切除术的患者。收集并分析基本资料、术中资料、并发症及随访时间。结果共纳入35例患者,中位年龄59岁(38 ~ 82岁)。所有患者均接受微创手术。1例由机器人完成,只有2例因严重粘连而转为开放手术。手术时间中位数为174分钟,术中出血量中位数为100 mL。术后住院时间中位数为5天,范围为3 ~ 55天。ICG荧光显像染色32例(91.4%),荧光相机可见病变。中位随访时间为19.7个月,范围为1 ~ 40.2个月。中位无复发生存期为18.5个月。结论应用ICG荧光显像反复行腹腔镜肝切除术是一种安全可行的治疗复发性肝肿瘤的方法。
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引用次数: 1
Transvaginal natural orifice transluminal endoscopic surgery: A novel gasless technique to hysterectomy 经阴道自然孔腔内窥镜手术:一种新的无气子宫切除术技术
Q3 Medicine Pub Date : 2022-03-01 DOI: 10.1016/j.lers.2021.11.002
Suyash Naval , Shubhada Jajoo , Rucha Naval , Jayashri Rane

Transvaginal natural orifice transluminal endoscopic surgery (vNOTES), as a minimally invasive surgery technique, applies CO2 for creating pneumoperitoneum, and uses a closed system to through smoke evacuation from a dedicated outlet or port. It has the potential to generate aerosol in the operation room, which can lead to an increased risk of transmission of SARS-CoV-2. This technical note introduces a new technique of gasless pure vNOTES to hysterectomy using silicone face mask as a modified vNOTES port.

经阴道自然孔腔内窥镜手术(vNOTES)是一种微创手术技术,利用CO2制造气腹,采用封闭系统从专用出口或端口进行排烟。它有可能在手术室产生气溶胶,这可能导致SARS-CoV-2传播的风险增加。本技术说明介绍了一种使用硅胶面罩作为改进的vNOTES端口的无气纯vNOTES子宫切除术新技术。
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引用次数: 0
Induction of total laparoscopic hysterectomy adopted the marionette technique in peri-menopausal and post-menopausal CIN3 patients 围绝经期和绝经后CIN3患者采用牵线木偶技术诱导腹腔镜全子宫切除术
Q3 Medicine Pub Date : 2022-03-01 DOI: 10.1016/j.lers.2021.12.001
Tomonori Nagai, Kousuke Shigematsu, Yuichiro Kizaki, Yoshiko Kurose, Koki Samejima, Takahiro Uotani, Taichi Akahori, Shigetaka Matsunaga, Yasushi Takai

Objective

When performing cervical conization in post-menopausal cervical intraepithelial neoplasia 3 (CIN3) patients, the positive rate of endocervical cone margin and the incidence of postoperative cervical stenosis increase. This study summarized a 4-year experience of total laparoscopic hysterectomy as a treatment option for peri-menopausal and post-menopausal CIN3 patients at a single institution. Furthermore, it shared the refinement strategies used during the surgery.

Methods

This study retrospectively analyzed the medical records of CIN3 patient aged ≥45 years and who underwent open or laparoscopic hysterectomy at our institution from January 1, 2017 to December 31, 2020. Totally, 30 CIN3 patients were enrolled and divided into abdominal hysterectomy group and laparoscopic hysterectomy based on surgery method, with 5 patients and 25 patients respectively.

Results: Compared to the abdominal hysterectomy group, the perioperative blood loss (20 mL vs. 220 mL, p = 0.004) was less and the duration of in-hospital stay (7 d vs. 11 d, p < 0.001) were significantly shorter in the laparoscopic hysterectomy group. However, no significant differences in age at hysterectomy (53 y vs. 77 y, p = 0.054) and operative time (154.4 ± 27.8 min vs. 161.0 ± 62.4 min, p = 0.826) were observed between them. Diagnostic conization was performed in advance for 12 patients, and among them, 10 (83.3%) patients had positive endocervical cone margin. Postoperative intestinal obstruction was noted in one abdominal hysterectomy patient, no other complications were observed in the remaining patients.

Conclusion

Compared to conization, hysterectomy is more invasive; however, it is an acceptable treatment option for peri-menopausal and post-menopausal CIN3 patients. In such cases, opting for total laparoscopic hysterectomy adopted the marionette technique might be preferable because the procedure is less invasive.

目的绝经后宫颈上皮内瘤变3 (CIN3)患者行宫颈锥切术时,宫颈锥缘阳性率及术后宫颈狭窄发生率增高。本研究总结了4年腹腔镜全子宫切除术作为围绝经期和绝经后CIN3患者的治疗选择在单一机构的经验。此外,它还分享了手术过程中使用的改进策略。方法回顾性分析我院2017年1月1日至2020年12月31日行开放或腹腔镜子宫切除术的年龄≥45岁CIN3患者的病历。共纳入30例CIN3患者,根据手术方式分为腹式子宫切除术组5例,腹腔镜子宫切除术组25例。结果:与腹式子宫切除术组相比,围术期出血量(20 mL vs 220 mL, p = 0.004)较少,住院时间(7 d vs 11 d, p <0.001),腹腔镜子宫切除术组明显缩短。但两组患者的子宫切除术年龄(53岁vs 77岁,p = 0.054)和手术时间(154.4±27.8 min vs 161.0±62.4 min, p = 0.826)差异无统计学意义。对12例患者进行了提前圆锥诊断,其中10例(83.3%)患者颈腔锥缘阳性。1例腹部子宫切除术患者术后出现肠梗阻,其余患者无其他并发症。结论子宫切除术与锥切术相比创伤性更大;然而,对于围绝经期和绝经后CIN3患者,它是一种可接受的治疗选择。在这种情况下,选择采用牵线木偶技术的全腹腔镜子宫切除术可能更可取,因为该手术的侵入性较小。
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引用次数: 0
Vascular resections in minimally invasive surgery for pancreatic cancer 血管切除在胰腺癌微创手术中的应用
Q3 Medicine Pub Date : 2022-03-01 DOI: 10.1016/j.lers.2021.09.003
Janet W.C. Kung , Rowan W. Parks

Pancreatic ductal adenocarcinoma (PDAC) is characterised by poor oncological outcome and is the seventh cause of cancer-related deaths worldwide. With the advances in surgical technology, oncological treatment, and critical care, extended pancreatic resections including vascular resections have become more frequently performed in specialised centres. Furthermore, the boundaries of resectability continue to be pushed in order to achieve a potentially curative approach in selected patients in combination with neoadjuvant and adjuvant treatment strategies. This review gives an overview on the current state of venous and arterial resections in PDAC surgery with particular attention given to the minimally invasive approach.

胰腺导管腺癌(PDAC)的特点是肿瘤预后差,是全球癌症相关死亡的第七大原因。随着外科技术、肿瘤治疗和重症监护的进步,包括血管切除术在内的胰腺切除术在专门的中心进行得越来越频繁。此外,可切除性的界限继续被推动,以便在选定的患者中结合新辅助和辅助治疗策略实现潜在的治愈方法。本文综述了PDAC手术中静脉和动脉切除的现状,并特别关注微创入路。
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引用次数: 0
Safety assessment of dextrin hydrogel adhesion barrier (AdSpray®) for elective laparoscopic cholecystectomy 糊精水凝胶粘附屏障(AdSpray®)用于选择性腹腔镜胆囊切除术的安全性评估
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.1016/j.lers.2022.01.001
T. Masuda, H. Takamori, Moeko Kato, Chisho Mitsuura, Yuta Shiraishi, R. Itoyama, K. Shimizu, R. Karashima, H. Nitta, H. Baba
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引用次数: 0
Choledocholithiasis caused by anatomical variation of cystic duct: A case report and review of the literature 胆囊管解剖变异所致胆总管结石1例报告及文献复习
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.1016/j.lers.2021.12.004
Meng Tong, Yumeng Li, Xuedi Sun, Ying-Lin Wang, Shuai Yang, Bocheng Zhang, Feiyu Jia, Lijun Peng, Jinghua Liu
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引用次数: 0
Variations in the bifurcation level of the abdominal aorta, formation level of the inferior vena cava, and insertion level of the left renal vein into the inferior vena cava and their clinical importance in laparoscopic surgery 腹主动脉分叉水平、下腔静脉形成水平、左肾静脉插入下腔静脉水平的变化及其在腹腔镜手术中的临床意义
Q3 Medicine Pub Date : 2022-01-01 DOI: 10.1016/j.lers.2022.01.002
Mustafa Khader, T. G. Al-Hyasat, I. Salameh, A. Shatarat
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引用次数: 0
Laparoscopic management of ventral hernia repair using intraperitoneal synthetic mesh: A 10-year retrospective observational study 腹腔镜下腹膜内合成补片腹疝修补:一项10年回顾性观察研究
Q3 Medicine Pub Date : 2021-12-01 DOI: 10.1016/j.lers.2021.11.003
Bramhavar Shamburao Ramesh, Hosni Mubarak Khan, Yashshwini B. Kareti

Objective

Ventral hernia is an anterior abdominal wall hernia, with an incidence of 2%–13%. Laparoscopic ventral hernia repair is the preferred method worldwide with all the advantages of the laparoscopic technique proven to be an effective treatment option. This study aims to assess the long-term outcomes of laparoscopic management of ventral hernia repair using intraperitoneal onlay mesh (IPOM) or intraperitoneal onlay mesh with defect closure (IPOM PLUS) technique with the usage of variety of synthetic meshes intraperitoneally.

Methods

A retrospective study of 821 patients of a single institution for a decade was conducted. Long-term outcomes such as pain, mesh infections, enterocutaneous fistula, bowel adhesions and recurrence were assessed.

Results

There were 801 primary, 12 incisional, and 8 recurrent hernia cases, including 532 females and 289 males with a mean age of 45.62±9.37 years. IPOM PLUS were underwent in 674 (82.10%) cases. Polypropylene, dual, titanium, composite meshes were applied in 473 (57.61%), 208 (25.33%), 82 (9.99%), and 58 (7.06%) cases respectively. Intraoperative bleeding occurred in 3 (0.37%) cases, seroma in 8 (0.97%), wound infection in 4 (0.49%), stitch abscess in 2 (0.24%). Recurrence was found in 8 (0.97%) cases, with 5 used polypropylene mesh and 3 used dual mesh. Mesh infections were discovered in 6 (2.88%) cases used dual, and foreign body sensation in 4 (0.85%) cases used polypropylene. Three (0.37%) patients had suture site hernia, and 3 (0.37%) had chronic sinus.

Conclusion

IPOM or IPOM PLUS holds good in small or medium sized ventral hernias. The safety and efficacy of intraperitoneal polypropylene mesh is comparable to that of other synthetic meshes. A mesh overlap of minimum 5 cm beyond defect edge is must to minimise hernia recurrence. Absorbable suture can be considered as alternative to tackers.

目的腹壁疝是一种前腹壁疝,发生率为2% ~ 13%。腹腔镜腹疝修补术是世界范围内的首选方法,腹腔镜技术的所有优点被证明是一种有效的治疗选择。本研究旨在评估使用腹膜内嵌补片(IPOM)或腹膜内嵌补片缺损闭合(IPOM PLUS)技术并使用多种合成腹膜内补片的腹腔镜腹疝修补术的长期疗效。方法对某医院821例患者进行10年的回顾性研究。评估长期预后,如疼痛、补片感染、肠皮瘘、肠粘连和复发。结果原发性疝801例,切口疝12例,复发疝8例,其中女性532例,男性289例,平均年龄45.62±9.37岁。674例(82.10%)行IPOM +治疗。聚丙烯网、双网、钛网、复合网分别为473例(57.61%)、208例(25.33%)、82例(9.99%)和58例(7.06%)。术中出血3例(0.37%),血清肿8例(0.97%),伤口感染4例(0.49%),针孔脓肿2例(0.24%)。复发8例(0.97%),其中聚丙烯补片5例,双补片3例。双补片组6例(2.88%)出现补片感染,聚丙烯组4例(0.85%)出现异物感。缝合处疝3例(0.37%),慢性鼻窦3例(0.37%)。结论IPOM或IPOM +治疗中小型腹疝效果较好。聚丙烯腹膜网的安全性和有效性与其他合成网相当。为了尽量减少疝的复发,补片的重叠必须超过缺损边缘至少5厘米。可吸收缝合线可被认为是粘接剂的替代品。
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引用次数: 2
Erratum regarding previously published articles 关于以前发表的文章的勘误
Q3 Medicine Pub Date : 2021-12-01 DOI: 10.1016/j.lers.2021.10.002
{"title":"Erratum regarding previously published articles","authors":"","doi":"10.1016/j.lers.2021.10.002","DOIUrl":"https://doi.org/10.1016/j.lers.2021.10.002","url":null,"abstract":"","PeriodicalId":32893,"journal":{"name":"Laparoscopic Endoscopic and Robotic Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468900921000682/pdfft?md5=a36fdff42882d2aea1eb53388a318a38&pid=1-s2.0-S2468900921000682-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91661265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Virtual reality simulation in training endoscopic skills: A systematic review 内窥镜技能训练中的虚拟现实模拟:系统综述
Q3 Medicine Pub Date : 2021-12-01 DOI: 10.1016/j.lers.2021.09.002
Wenlan Zhang , Xin Liu , Bin Zheng

Objective

Training young physicians in gastrointestinal endoscopy through virtual reality (VR) simulators has become popular. It is important to evaluate the benefits and usefulness of this technology for teaching endoscopic skills. The objective of this literature review is to understand the benefits of VR technology through quantitative and qualitative examination of learning outcomes.

Methods

A literature search of 7 databases was conducted. Studies which compared the effects of learning through VR simulation and another method of learning were included. In addition, studies were included if they evaluated learning outcomes on clinical patients. Participants could be medical residents, fellows, physicians, or nurses. Common outcomes measured across studies included subjective overall performance scores, total procedure times, rate of successful procedure completion, error rates, patient pain or discomfort, and measures of independence.

Results

A total of 22 studies were included. Overall, VR simulation training was seen to be comparable or significantly better than clinical training, no training, other types of simulation, and another form of VR training. Many authors reported increasing patient safety, reducing stress and time constraints, and shortening the learning curve as advantages of VR simulation training. However, this form of training is also expensive and may result in the learning of bad habits.

Conclusion

VR simulation technology can be a valuable form of educating endoscopy novices if properly supervised during training, and if there is also integration of clinical training.

目的利用虚拟现实(VR)模拟器对年轻医师进行胃肠道内窥镜检查培训已成为一种流行趋势。评估这种技术在内镜技能教学中的益处和有用性是很重要的。本文献综述的目的是通过对学习成果的定量和定性检查来了解VR技术的好处。方法对7个数据库进行文献检索。研究比较了通过VR模拟学习和另一种学习方法的效果。此外,如果研究评估了临床患者的学习结果,则将其纳入研究。参与者可以是住院医师、研究员、医生或护士。研究中测量的常见结果包括主观总体表现评分、总手术时间、手术成功率、错误率、患者疼痛或不适以及独立性测量。结果共纳入22项研究。总体而言,虚拟现实模拟培训被认为与临床培训、无培训、其他类型的模拟和另一种形式的虚拟现实培训相当或显著优于临床培训。许多作者报告了VR模拟训练的优点,包括提高患者安全性、减少压力和时间限制、缩短学习曲线。然而,这种形式的训练也很昂贵,可能会导致坏习惯的学习。结论如果在培训过程中进行适当的指导,并与临床培训相结合,vr模拟技术可以成为一种有价值的内窥镜培训形式。
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引用次数: 8
期刊
Laparoscopic Endoscopic and Robotic Surgery
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