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Skeletal Metastases In Apparently Operable Lung Cancer Evaluated With Whole Body Bone Scan – A Pilot Study In South India. 用全身骨扫描评估明显可手术肺癌的骨骼转移-印度南部的一项试点研究。
Pub Date : 2009-12-31 DOI: 10.5580/b96
A. Shinto, L. Pachen, K. SreekanthT, C. Joseph
Study objectives: The management of patients diagnosed with non-small cell lung cancer is dependant on the stage of disease, which is also crucial for prognosis and selection of an appropriate treatment regimen. Historically a whole body bone scan has been used to identify skeletal metastases. The aim of this study was to investigate the usefulness of whole-body bone scanning (BS) in detecting bone metastases in newly diagnosed and apparently operable cases of lung cancer. Design and patients: Ninety two patients with a diagnosis made between 2008 and 2010 were recruited (squamous cell carcinoma, n =29; adenocarcinoma, n=36 ; non-small cell carcinoma, n= 22; others n=5). None of these patients had clinical factors suggesting bone metastasis (skeletal pain, elevated alkaline phosphatase, hypercalcemia). BS was performed in all patients, and additional imaging or biopsy was ordered in patients where there were doubtful lesions. Measurements and results: Bone metastases were detected in 14.13 % (n =13 ) of 92 clinical factor-negative patients. Of the eighteen abnormal bone scan results (eleven positive and seven probable), thirteen were true-positive and the five remaining were false-positive. In our study, PPV of the BS was 72.2%. Skeletal metastases was found more commonly in adenocarcinoma (46.15%, n=6 ) than other cell types. In 13 patients diagnosed with metastases, 53.8 % (n=7) were patients with non-small cell lung cancer and 38.4% (n=5) with small cell lung cancer. 4 of the 18 patients (22.2%) in T2N0M0 clinical stage had bone metastases. The routine bone scanning prevented thirteen futile thoracotomies (14%) in 92 patients with apparently operable lung cancer. Conclusions: Though clinical factors have a high NPV and the bone scans have less than desired specificity in diagnosing metastases, BS could be considered in those asymptomatic patients as a part of their work up and staging, in whom operative intervention is contemplated.
研究目的:诊断为非小细胞肺癌的患者的处理取决于疾病的分期,这对预后和选择合适的治疗方案也至关重要。历史上,全身骨扫描已被用于识别骨骼转移。本研究的目的是探讨全身骨扫描(BS)在新诊断和明显可手术的肺癌病例中检测骨转移的有效性。设计和患者:在2008年至2010年间确诊的92例患者被纳入研究(鳞状细胞癌,n =29;腺癌,n=36;非小细胞癌,n= 22;其他人n = 5)。这些患者均无提示骨转移的临床因素(骨骼疼痛、碱性磷酸酶升高、高钙血症)。所有患者都进行了BS检查,对于有可疑病变的患者,要求进行额外的影像学检查或活检。测量和结果:在92例临床因素阴性患者中,14.13% (n =13)检测到骨转移。在18例异常骨扫描结果(11例阳性,7例可能)中,13例为真阳性,其余5例为假阳性。在我们的研究中,BS的PPV为72.2%。骨骼转移在腺癌中更为常见(46.15%,n=6)。在13例确诊为转移的患者中,53.8% (n=7)为非小细胞肺癌患者,38.4% (n=5)为小细胞肺癌患者。T2N0M0临床分期18例患者中有4例(22.2%)发生骨转移。在92例明显可手术的肺癌患者中,常规骨扫描避免了13例无效的开胸手术(14%)。结论:尽管临床因素具有较高的NPV,骨扫描在诊断转移性方面的特异性低于预期,但对于那些无症状的患者,BS可以作为其工作和分期的一部分,考虑进行手术干预。
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引用次数: 3
Successful removal of a very large left atrial organized infected thrombus (weight 200 gram) and Mitral valve replacement: A case report. 成功移除一个很大的左房有组织感染血栓(重200克)和二尖瓣置换术:1例报告。
Pub Date : 2009-12-31 DOI: 10.5580/99
M. Yunus, M. K. Saikia, Nari M. Lyndoh, Rajani Thabah, J. Bardoloi, S. Day, C. Selvam
Successful removal of a very large left atrial organized infected thrombus (weight 200 gram) and Mitral valve replacement: A case report. Abstract LA thrombus is common in mitral valve disease. They are even more commonly seen after an episode of AF. This thrombus may cause sudden circulatory arrest and systemic embolization. In this case we report a very large organized infected thrombus in the LA with severe MS. An emergency open heart surgery was conducted and successful removal of thrombus and mitral valve replacement with prosthetic valve was done.
成功移除一个很大的左房有组织感染血栓(重200克)和二尖瓣置换术:1例报告。摘要LA血栓在二尖瓣疾病中很常见。它们在房颤发作后更常见。这种血栓可引起突然循环骤停和全身栓塞。在这个病例中,我们报告了一个非常大的有组织的感染血栓,并伴有严重的ms。我们进行了紧急心脏直视手术,成功地取出了血栓,并用人工瓣膜置换了二尖瓣。
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引用次数: 1
Management of the persistent sciatic artery with coexistent aortoiliac aneurysms; endovascular and open techniques. 持续性坐骨动脉并发主髂动脉瘤的治疗血管内和开放技术。
Pub Date : 2009-12-31 DOI: 10.5580/630
A. Rodriguez-Rivera, L. Sandberg, A. Ahmadinejad, C. Tzarnas, Steve Thuahnai
Patients with coexistent aortoiliac aneurysms and persistent sciatic artery (PSA) run the risk of postoperative complications. This can occur with open or endovascular procedures. EVAR with coiling of the internal iliac artery is one of the situations where ischemia may occur. We report a case where open aortic aneurysm repair with isolation and bypass of the PSA were performed with an excellent result. We recommend routine careful preoperative analysis of the CT angiogram and / or angiogram to rule out PSA.
同时存在髂主动脉动脉瘤和持续性坐骨动脉(PSA)的患者存在术后并发症的风险。这可能发生在开放或血管内手术中。髂内动脉盘绕的EVAR是可能发生缺血的情况之一。我们报告一个病例,其中开放的主动脉瘤修复与隔离和旁路的PSA进行了极好的结果。我们建议术前例行仔细的CT血管造影和/或血管造影分析,以排除PSA。
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引用次数: 2
Aortic Insufficiency By Blunt Chest Trauma. 钝性胸外伤引起的主动脉功能不全。
Pub Date : 2009-12-31 DOI: 10.5580/139a
S. Tatebe, Yoshiro Chiba
A 76-year-old male presented with exertional dyspnea 5 months after motor vehicle accident. Preoperative echocardiography showed aortic insufficiency(AI) due to partial detachment of the non coronary cusp. He was successfully treated by valve replacement surgery. Postoperative examination of the excised aortic valve had no changes related to endocardiatis, but suggestive of traumatic AI. The issues attached to traumatic AI including lapse of time from blunt cheat trauma to onset of AI were discussed.
一位76岁男性在机动车事故发生后5个月出现运动性呼吸困难。术前超声心动图显示主动脉不全(AI)是由非冠状动脉尖端部分脱离引起的。他通过瓣膜置换术成功治疗。术后检查切除主动脉瓣未见与心内膜相关的改变,但提示创伤性AI。讨论了创伤性AI所附带的问题,包括从钝性欺骗创伤到AI发作的时间流逝。
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引用次数: 1
One-Stage Mitral Valve Replacement And Splenectomy In Splenic Infarcts And Infective Endocarditis 一期二尖瓣置换术和脾切除术治疗脾梗死和感染性心内膜炎
Pub Date : 2009-12-31 DOI: 10.5580/228f
V. Gegouskov, P. Petrov, D. Simov, V. Danov, J. Blagov, S. Petrov
Infective endocarditis associated with spleen infarcts is common and very complicated condition. Splenic lesions in infective endocarditis are presented of infarcts and abscesses. Operative mortality in such patients is high. The septic status, heart failure, hemodynamic instability, renal dysfunction make the success much difficult. Use of abdominal Computed Tomography to locate infectious sources is of paramount importance for the treatment plan. We present one case of infective endocarditis, complicated by infected splenic infarcts and heart failure. On urgent conditions we performed one-stage mitral valve replacement and splenectomy.
感染性心内膜炎合并脾梗死是一种常见且非常复杂的疾病。感染性心内膜炎的脾损害表现为梗死和脓肿。这类患者的手术死亡率很高。脓毒症、心力衰竭、血流动力学不稳定、肾功能不全使手术成功非常困难。使用腹部计算机断层扫描来定位感染源对治疗计划至关重要。我们报告一例感染性心内膜炎,并发感染性脾梗死和心力衰竭。在紧急情况下,我们进行了一期二尖瓣置换术和脾切除术。
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引用次数: 2
Acute Popliteal Artery Embolism Due To Ruptured Mediastinal Hydatid Cyst Into Thoracic Aorta – A Case Report . 纵隔包虫囊肿破裂致胸主动脉急性腘动脉栓塞1例。
Pub Date : 2009-12-31 DOI: 10.5580/2370
M. Mushtaque, P. Khan, M. F. Mir, S. Khanday
A 40 year old female presented with the clinical features suggestive of acute arterial occlusion of the right leg for one day . Compression Ultrasonography revealed a linear membrane like defect in the right popliteal artery suggestive of an embolus . Patient was subjected to emergency catheter embolectomy revealing a laminated hydatid membrane within the artery . The patient was evaluated postoperatively and CECT chest documented a primary mediastinal hydatid cyst eroding into descending thoracic aorta . The mediastinal lesion was later treated with total cyst excision . In endemic areas, it is important to consider hydatid cysts in the differential diagnosis of an acute arterial occlusion .
女性,40岁,临床表现为右腿急性动脉闭塞1天。压缩超声显示右侧腘动脉线状膜样缺损提示栓子。患者接受急诊导管栓塞切除术,在动脉内发现层状包虫膜。患者术后接受检查,CECT胸部显示原发性纵隔包虫病囊肿侵蚀至胸降主动脉。纵隔病变后采用全囊肿切除治疗。在流行地区,重要的是要考虑包虫囊肿鉴别诊断急性动脉闭塞。
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引用次数: 0
A Delayed Diaphragmatic Hernia A延迟性膈疝
Pub Date : 2009-12-31 DOI: 10.5580/2612
N. DeepakA, V. Rathee, Nityasha, V. Malik, R. Dahiya
In surgical practice, diaphragmatic injuries are present in 1-7 % of people with significant blunt trauma and an average of 3% abdominal injuries. Diaphragmatic rupture resulting from blunt trauma is still not suspected by many surgeons. We encountered an interesting case, where a traumatic diaphragmatic hernia could only be diagnosed after 20 days of the initial chest trauma and that too because of intercostal thoracostomy tube drain showed food particles. CT scan revealed abdominal contents in the chest and thoracostomy tube was placed inside the stomach. He was successfully managed by exploratory laparotomy, closure of perforation and diaphragm repair with a prolene sutures.
在外科实践中,1- 7%的钝性外伤患者有膈肌损伤,平均3%的患者有腹部损伤。许多外科医生仍然没有怀疑钝性创伤导致的膈破裂。我们遇到了一个有趣的病例,创伤性膈疝只能在最初的胸部创伤20天后诊断出来,这也是因为肋间开胸管引流显示出食物颗粒。CT扫描显示腹部内容物在胸部和胸腔造瘘管放置在胃内。他成功地通过剖腹探查、缝合穿孔和膈膜缝合修复。
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引用次数: 0
Does Coronary Artery Bypass Grafting Without Cardiopulmonary Bypass Reduce Costs in Cardiac Surgery 不进行体外循环的冠状动脉旁路移植术能降低心脏手术的成本吗
Pub Date : 2009-12-31 DOI: 10.5580/1de6
E. Hijazi
Technical improvements in coronary revascularization over the past decade have led to a revival of interest in off-pump coronary artery bypass surgery. Cost containment in coronary artery bypass surgery is becoming increasingly important in modern hospital management. Therefore, further savings could be obtained by using a surgical technique able to decrease the fixed direct cost while maintaining clinical quality of care. Economic considerations are an extremely important issue in evaluating the role of off-pump coronary artery bypass grafting in the future of cardiac surgery, as off-pump coronary artery bypass grafting is expected to lower costs by reducing perioperative morbidity and recovery time. However, the acceptance of this procedure as a routine alternative for the treatment of coronary artery disease will depend on both long-term graft patency rates as well as a competitive market cost. This review examines these effects.
在过去的十年里,冠状动脉血管重建术的技术进步已经引起了人们对非体外循环冠状动脉搭桥手术的兴趣。冠状动脉搭桥术的成本控制在现代医院管理中越来越重要。因此,通过使用一种能够在保持临床护理质量的同时减少固定直接成本的手术技术,可以获得进一步的节省。在评估非体外循环冠状动脉旁路移植术在未来心脏手术中的作用时,经济考虑是一个极其重要的问题,因为非体外循环冠状动脉旁路移植术有望通过减少围手术期发病率和恢复时间来降低成本。然而,接受这种手术作为治疗冠状动脉疾病的常规选择将取决于长期的移植物通畅率以及具有竞争力的市场成本。这篇综述探讨了这些影响。
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引用次数: 0
Modification Of The Extracardiac Total Cavopulmonary Connection - Placement Of A Graft Antero-Medially Rather Than Laterally 心外全腔肺连接的改良——将移植物置于前内侧而非外侧
Pub Date : 2009-12-31 DOI: 10.5580/1b5e
M. Nagashima, F. Shikata, T. Okamura, K. Kawachi, T. Higaki, F. Suetsugu
In the conventional extracardiac total cavopulmonary connection (TCPC), a graft is placed lateral to the atrium. To prevent pulmonary venous obstruction, a thorough dissection around the pulmonary veins is required. The cause of sinus node dysfunction after extracardiac TCPC is still unknown. One possibility may be a compression of the sinus node from the outside by the graft. In this report, we proposed to modify TCPC by implanting a graft antero-medially rather than laterally to prevent the aforementioned complications. Six patients underwent this modified technique of TCPC. There was no death. The average pulmonary arterial pressure was 11 mmHg. The average follow-up was 24 months. No pulmonary venous stenosis or sinus node dysfunction was observed. In the conventional TCPC, the flow from the superior vena cava directly collides with the flow from the inferior vena cava at the central pulmonary artery (PA) resulting in energy loss. The central PA slightly curves anteriorly to posteriorly. In this modified technique, the flow from the graft enters the central PA from the front and may smoothly advance backwards into the distal PA along its naturally curved line. Thus, this modified technique may produce less energy loss compared to the conventional extracardiac TCPC.
在传统的心外全腔肺连接(TCPC)中,移植物放置在心房外侧。为了防止肺静脉阻塞,需要在肺静脉周围进行彻底的解剖。心外TCPC术后窦结功能障碍的原因尚不清楚。一种可能是移植物从外部压迫窦结。在本报告中,我们建议通过在前内侧而不是外侧植入移植物来改良TCPC,以防止上述并发症。6例患者接受了这种改良的TCPC技术。没有死亡。平均肺动脉压为11 mmHg。平均随访时间为24个月。未见肺静脉狭窄或窦房结功能障碍。在传统的TCPC中,来自上腔静脉的血流直接与来自下腔静脉的血流在肺动脉中央动脉(PA)发生碰撞,导致能量损失。中央PA前向后略微弯曲。在这种改良的技术中,来自移植物的血流从前部进入中央PA,并可以沿着其自然弯曲的线平滑地向后进入远端PA。因此,与传统的心外TCPC相比,这种改良的技术可能产生更少的能量损失。
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引用次数: 0
Manubriosternal Joint Dislocation- A Treatment Dilemma 胸骨关节脱位-治疗困境
Pub Date : 2009-12-31 DOI: 10.5580/1c3c
W. Salloum, N. Nikolaidis, D. Weeden
Manubriosternal joint dislocation is extremely rare and yet there is no definite standard for treating such injury. The reported results of conservative or surgical approach vary between patients. We report a case where different methods of treatment were tried. However, controlling symptoms could only be established by stabilizing the joint using a plate fixation.
胸骨关节脱位是非常罕见的,但目前尚无明确的治疗标准。报告的保守或手术方法的结果因患者而异。我们报告一个案例,其中不同的治疗方法进行了尝试。然而,控制症状只能通过使用钢板固定稳定关节来建立。
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引用次数: 3
期刊
The Internet Journal of Thoracic and Cardiovascular Surgery
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