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Idiopathic Chronic Hemorrhagic Pericarditis 特发性慢性出血性心包炎
Pub Date : 2008-12-31 DOI: 10.5580/169e
A. Gürbüz, U. Yetkin, C. Özbek, O. Gokalp, smail Yürekli, A. Çall, N. Postac, Murat Ye il
Pericardial diseases imitate more common cardiac diseases and therefore can be difficult to diagnose. We describe a case of idiopathic chronic hemorrhagic pericarditis. A pragmatic clinical and scientific approach for improved diagnosis of pericardial diseases is outlined
心包疾病类似于更常见的心脏疾病,因此很难诊断。我们报告一例特发性慢性出血性心包炎。本文概述了一种实用的临床和科学的方法来改善心包疾病的诊断
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引用次数: 0
Our strategy of coronary bypass procedure in a case with bicuspid aortic valve and mild dilation of ascending aorta 我们的策略冠状动脉旁路手术的情况下,二尖瓣主动脉瓣和轻度扩张的升主动脉
Pub Date : 2008-12-31 DOI: 10.5580/1398
U. Yetkin, K. Erguneş, Aykut Şahin, I. Yurekli, A. Gürbüz
Bicuspid aortic valve is the most common congenital cardiac anomaly in the adult population including other cardiovascular diseases.In this study we present our strategy of coronary bypass procedure in a case with bicuspid aortic valve and mild dilation of ascending aorta.
二尖瓣主动脉瓣是成人最常见的先天性心脏异常,包括其他心血管疾病。在这项研究中,我们提出我们的策略冠状动脉旁路手术的情况下,二尖瓣主动脉瓣和轻度扩张的升主动脉。
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引用次数: 0
Using Of Levosimendan In A Redo Cardiac Pediatric Operation 左西孟旦在小儿心脏手术中的应用
Pub Date : 2008-12-31 DOI: 10.5580/126
M. Aksun, A. Gürbüz, Ufuk Yetk n, Ertan Damar, Banu Lafç, A. Özelçi, T. Goktogan, N. Karahan
Levosimendan (LS), a new inodilator used in the treatment of decompensate heart failure, has been reported to be effective in patients with high perioperative risks, with abnormal left ventricular function, and who face difficulties in weaning off cardiopulmonary bypass. Cause of its many beneficial effects, the use of LS in cardiac surgery arises. However, experiences about the use of LS in pediatric patients are limited. We administered LS in a case of 3 years old child who developed heart failure during cardiopulmonary bypass removal period. A 3 years old, 11 kg female child was admitted in our center who had a total revision of tetralogy of Fallot four months ago. Any postoperative complaints or symptoms were not present since we find out a large progressive aneurysm in the echocardiographic evaluation of the otogen pericardial patch which was prepared with gluteraldehide. Induction of anesthesia was done with 2 mg/kg ketamin and 0.5 mg/kg atracurium, 20μg/kg atropin was administered also. After endotracheal entubation, invasive blood pressure of the left radial artery and central venous pressure monitoring of the right internal jugular vein was successfully. After the excision of the pericardial patch, the repair of the right ventricular outflow was done with e-PTFE graft. At the end of cardiopulmonary bypass (CPB) surgery deep hypotension occurred. In spite of dopamine (15 μg/kg/min), dobutamine (15μg/kg/min) and adrenalin (1mg/h) infusions, myocardium failed to maintain normotension. Diuresis was suboptimal in our patient also. Upon these LS infusion was started with the loading dose of 12 μg/kg over 10 minutes. Later, 0.2 μg/kg/min maintenance dosage was applied. In an hour we observed 200 cc diuresis and the vital signs were taken under control. LV infusion was completed after 24 hours postoperatively in our intensive care unit. Six hours later we started to reduce the analogous inotropic support (dopamine 10μg/kg/min, dobutamine 10μg/kg/min, adrenalin 0.5mg/h) since the hemodynamic parameters were satisfactory. Twelve hours later another reduction was applied. Since the well tolerance of the myocardium, we were able to stop the other inotropic drug infusions after 48 hours and the patient was discharged from the hospital 10 days after the surgery. Our clinical experiences with LS has shown that it reduces conventional inotropic agents dosages and could be a satisfactory agent in myocardial depression therapy which occurred in CPB surgery intraoperatively also in pediatric patients. However the need for serial randomized controlled studies in pediatric patient about the use of LS is indisputable.
左西孟旦(LS)是一种用于治疗失代偿性心力衰竭的新型扩张剂,已被报道对围手术期高危、左心室功能异常和体外循环困难的患者有效。由于其许多有益的作用,在心脏手术中使用LS。然而,在儿童患者中使用LS的经验是有限的。我们对一个3岁的儿童进行了LS治疗,他在体外循环手术期间出现了心力衰竭。我们中心收治了一名3岁,11公斤的女婴,她于4个月前进行了法洛四联症的全面修订。我们在超声心动图评估中发现了一个巨大的进行性动脉瘤,该动脉瘤是用gluteraldehide制作的耳原心包贴片。氯胺酮2 mg/kg,阿曲库铵0.5 mg/kg,阿托品20μg/kg诱导麻醉。气管插管后成功监测左桡动脉有创血压及右颈内静脉中心静脉压。心包补片切除后,采用e-PTFE移植物修复右心室流出。在体外循环(CPB)手术结束时发生深度低血压。多巴胺(15μg/kg/min)、多巴酚丁胺(15μg/kg/min)和肾上腺素(1mg/h)均不能维持心肌的正常血压。本例患者的利尿效果也不理想。在此基础上,以12 μg/kg的负荷剂量10分钟内开始LS输注。后给予0.2 μg/kg/min维持剂量。一小时后,我们观察到利尿200毫升,生命体征得到控制。术后24小时在重症监护室完成LV输注。6小时后,由于血流动力学参数满意,我们开始减少类似的肌力支持(多巴胺10μg/kg/min,多巴酚丁胺10μg/kg/min,肾上腺素0.5mg/h)。12小时后又进行了一次复位。由于心肌耐受性良好,我们在48小时后停止了其他肌力药物的输注,患者在术后10天出院。我们的临床经验表明,它减少了传统的肌力药物的剂量,可以作为一种令人满意的药物用于心肌抑制治疗,这种药物发生在CPB手术中,也发生在儿科患者中。然而,需要在儿童患者中进行关于LS使用的系列随机对照研究是无可争议的。
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引用次数: 1
Complicated brucella endocarditis of the aortic valve 主动脉瓣并发布鲁氏菌心内膜炎
Pub Date : 2008-12-31 DOI: 10.5580/97c
C. Özbek, Ufuk Yetk n, B. Ozcem, smail Yürekl, A. Gürbüz
Endocarditis is a rare and the most fatal complication of brucellosis and can cause severe cardiac injuries.Generally aortic valve invasion is seen.We describe a case of Complicated brucella endocarditis of the aortic valve.
心内膜炎是一种罕见且最致命的布鲁氏菌病并发症,可导致严重的心脏损伤。通常可见主动脉瓣侵犯。我们报告一例复杂的布鲁氏菌心内膜炎的主动脉瓣。
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引用次数: 0
Clinical utility of magnetic resonance angiography for femoro-popliteal arterial occlusive disease 磁共振血管造影在股腘动脉闭塞性疾病中的临床应用
Pub Date : 2008-12-31 DOI: 10.5580/14a0
U. Yetkin, K. Erguneş, A. Özelçi, T. Goktogan, A. Gürbüz
Magnetic resonance angiography (MRA) has recently become instrumental in the diagnosis of arterial disease and is gaining an important role in the study of plaining revascularization.In this study we present clinical utility of magnetic resonance angiography for femoro-popliteal arterial occlusive disease.
磁共振血管造影(MRA)近年来已成为动脉疾病诊断的重要工具,并在血管重建研究中发挥着重要作用。在这项研究中,我们介绍了磁共振血管造影在股腘动脉闭塞性疾病中的临床应用。
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引用次数: 0
C-Reactive Proteins and Cardiovascular Risk Indices in Hypertensive Nigerians. 尼日利亚高血压患者的c反应蛋白与心血管危险指标
Pub Date : 2008-12-31 DOI: 10.5580/fa9
J. Idemudia, E. Ugwuja, O. Afonja, Idogun Es, N. Ugwu
C-reactive protein (CRP), a biomarker of inflammation, has been found to play a role in the pathogenesis of cardiovascular disease and its determination has been proposed as one method of improving the prediction of the risk of cardiovascular events. CRP was determined in 150 hypertensive patients aged 30-59 years and 30 apparently healthy normotensive individuals matched for age and socioeconomic status by ELISA technique. Atherogenic index (LDL-C/HDL-C) and coronary heart disease risk (HDL-C/TC) were also calculated from the lipid profile. Among the hypertensive patients, only 1 (1.2%) female had a dangerous coronary heart disease risk, while 14 (9.3%) (6 males and 8 females) were at high risk of CHD and only 16 (10.7%) (11 males and 5 females) had probable protection against CHD. Hypertensive patients were significantly (p < 0.05) heavier than the normotensive patients (28.34 ± 4.40kg/m vs. 25.79 ± 2.91kg/m), with significantly higher atherogenic indices and CRP. Among the hypertensive patients, CRP positively correlated with atherogenic index (r = 0.551, p < 0.05) and CHD risk (r = 0.589, p < 0.05). However, in normotensive patients, CRP was positively correlated with atherogenic index (r = 0.492, p < 0.01) but negatively correlated with CHD risk (r = -0.475, p < 0.01). In conclusion, hypertensive Nigerians have significantly higher CRP than their normotensive counterparts, which correlates with CHD risk.
c反应蛋白(CRP)是炎症的生物标志物,在心血管疾病的发病机制中起着重要作用,其测定已被提出作为改善心血管事件风险预测的一种方法。采用酶联免疫吸附试验(ELISA)对150例30 ~ 59岁的高血压患者和30例年龄和社会经济状况相匹配的表面健康正常人群进行CRP测定。根据脂质谱计算动脉粥样硬化指数(LDL-C/HDL-C)和冠心病风险(HDL-C/TC)。在高血压患者中,仅有1例(1.2%)女性有冠心病危险,14例(9.3%)(男性6例,女性8例)有冠心病高危,仅有16例(10.7%)(男性11例,女性5例)有可能预防冠心病。高血压患者的体重(28.34±4.40kg/m vs. 25.79±2.91kg/m)显著高于正常患者(p < 0.05),其动脉粥样硬化指数和CRP均显著高于正常患者。在高血压患者中,CRP与动脉粥样硬化指数(r = 0.551, p < 0.05)、冠心病风险(r = 0.589, p < 0.05)呈正相关。而在血压正常的患者中,CRP与动脉粥样硬化指数呈正相关(r = 0.492, p < 0.01),与冠心病风险呈负相关(r = -0.475, p < 0.01)。综上所述,尼日利亚高血压患者的CRP水平明显高于正常者,这与冠心病风险相关。
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引用次数: 8
Successful Mitral Valve Repair and Ring Annuloplasty In A Case With Giant Left Atrial Thrombus 巨大左房血栓二尖瓣修复及环成形术成功一例
Pub Date : 2008-12-31 DOI: 10.5580/2119
Ufuk Yetk n, C. Özbek, M. Akyüz, A. Çallı, Ali Gürbüz
Left atrial ball thrombus appears to be uncommon. Ball thrombi of the left atrium are usually observed with mitral valve disease.In this study ,we report a case of successful mitral valve repair and ring annuloplasty in a case with giant left atrial thrombus. Removal of the ball thrombus and mitral valve repair were performed simultaneously.Early diagnosis and emergent surgical intervention are mandatory for giant left atrial thrombus
左心房球型血栓并不常见。左心房球型血栓常见于二尖瓣病变患者。在这个研究中,我们报告一个成功的二尖瓣修复和环成形术在一个巨大的左心房血栓的病例。球型血栓清除术和二尖瓣修复术同时进行。早期诊断和紧急手术治疗是巨大左心房血栓的必要条件
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引用次数: 0
Statins in the Treatment of Type 2 Diabetes Mellitus: A Systematic Review. 他汀类药物治疗2型糖尿病:系统综述。
Pub Date : 2008-12-31 DOI: 10.5580/2443
C. Anyanwu, C. Nosiri
Globally, Type 2 diabetes mellitus (T2DM) continues to prove a huge challenge to patients and clinicians. Treatment of T2DM has traditionally been focused on the regulation of sugar in the blood with diet and drugs. Substantial epidemiological data has demonstrated since the 1970s that cardiovascular diseases (CVD) constitute the primary cause of morbidity and mortality in patients with diabetes. This systematic review was aimed at using clinical trials on published literature to pull out evidence based medicine to support or discount the mortality benefits of statin therapy in T2DM patients. From the clinical trials reviewed, statin therapy in non diabetic and T2DM showed varying degrees of reduction in CHD events. Pravastatin therapy reduced the risk among all patients from 15.9 % to 12.3% (relative risk reduction (RRR) 24%). In diabetics, the RRR was 19%. Same therapy reduced the risk of stroke from 9.9% to 6.3% in diabetic group. Another study observed in their results a significant reduction in mortality (1328:12.9%) deaths among 10,269 patients in the simvastatin group versus 1507: 14.7% among 10,267 patients in the placebo group. Other studies also reported significant or near significant reduction in mortality or death rate. Artovastatin reduced acute CHD events by 36%, coronary revascularization by 31% and rate of stroke by 48%. Pravastatin on the other hand showed 25% reduction of risk of coronary events (CHD, death, non fatal myocardial Infarction (MI) and coronary artery by pass graft (CABG)). Another study showed that patients with T2DM and other risk factors of coronary artery disease or retinopathy had a 35% relative risk reduction in CVD when Atorvaststin 10mg was given daily which was similar to a 33% relative risk reduction in CVD with Simvastatin 40mg. Other clinical trials showed significant evidence that the pharmacological treatment with statins reduced mortality and morbidity associated with CVD especially those who are already at higher risk of CHD events, such as patients with T2DM while long term treatment is often necessary.
在全球范围内,2型糖尿病(T2DM)仍然是患者和临床医生面临的巨大挑战。传统上,T2DM的治疗重点是通过饮食和药物调节血糖。自20世纪70年代以来,大量流行病学数据表明,心血管疾病(CVD)是糖尿病患者发病和死亡的主要原因。本系统综述的目的是利用已发表文献的临床试验,以证据为基础的医学来支持或贬低他汀类药物治疗2型糖尿病患者的死亡率。从所回顾的临床试验来看,他汀类药物治疗在非糖尿病和2型糖尿病患者中显示出不同程度的冠心病事件降低。普伐他汀治疗将所有患者的风险从15.9%降低到12.3%(相对风险降低(RRR) 24%)。在糖尿病患者中,这一比例为19%。同样的治疗将糖尿病组中风的风险从9.9%降低到6.3%。另一项研究在他们的结果中观察到,辛伐他汀组10269例患者的死亡率(1328:12.9%)显著降低,而安慰剂组10267例患者的死亡率为1507:14.7%。其他研究也报告死亡率或死亡率显著或接近显著降低。阿托伐他汀可使急性冠心病发生率降低36%,冠状动脉血运重建术降低31%,卒中发生率降低48%。另一方面,普伐他汀显示冠状动脉事件(冠心病、死亡、非致死性心肌梗死(MI)和冠状动脉旁路移植(CABG))的风险降低25%。另一项研究显示,当每日给予阿托伐他汀10mg时,伴有T2DM和其他冠状动脉疾病或视网膜病变危险因素的患者发生CVD的相对风险降低了35%,这与每日给予辛伐他汀40mg时CVD的相对风险降低33%相似。其他临床试验显示,他汀类药物治疗降低了与CVD相关的死亡率和发病率,特别是那些已经处于冠心病事件高风险的患者,如T2DM患者,而长期治疗往往是必要的。
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引用次数: 0
Portal vein aneurysm due to traumatic etiology 外伤性门静脉动脉瘤
Pub Date : 2008-12-31 DOI: 10.5580/f7d
Ay egül Sars lmaz, Melda Apayd n, U. Yetkin, Ergun Öziz, M. Varer, smail Yürekli, E. Uluç, A. Gürbüz
Portal vein aneurysm is a rare clinical entity. We describe a case of portal vein aneurysm due to traumatic etiology. Our patient had no signs suggestive of portal hypertension; the lesion was incidentally detected by ultrasound. It appears that these aneurysms can be found at any age and that there is no sexual preference. This pathology is increasingly encountered with the frequent use of radiological imaging modalities. INTRODUCTION Portal vein aneurysm is a rare clinical entity, with only 41 published cases in the English-language literature. Twentyfive of them were congenital(1). Portal venous aneurysms are described as focal dilatations of the portal venous system(2).Generally it was incidentally diagnosed during an investigation for dyspepsia(1). CASE PRESENTATION Our case was a 65-year-old male. He was suffering from flatulance and dyspepsia for 2 years. His past medical history was significant for a blunt trauma to the right upper quadrant of the abdomen he had experienced 19 years ago due to a traffic accident. Upper abdominal ultrasound imaging was carried out for a possible diagnosis of cholelithiasis. A venous aneurysm of 28x24 mm corresponding to the proximal zone of left branch of portal vein next to the falciform ligament. (Figures 1 and 2). Figure 1 Figure 1 Portal vein aneurysm due to traumatic etiology 2 of 4 Figure 2 Figure 2 Color Doppler ultrasound imaging revealed venous aneurysmal dilation with continuous flow pattern as in the case with portal flow (Figure 3).
门静脉动脉瘤是一种罕见的临床疾病。我们报告一例外伤性门静脉动脉瘤。我们的病人没有门静脉高压症的迹象;病变是偶然用超声波发现的。这些动脉瘤似乎可以在任何年龄发现,而且没有性别偏好。这种病理越来越多地遇到与频繁使用放射成像模式。门静脉动脉瘤是一种罕见的临床疾病,在英文文献中仅报道41例。其中25例是先天性的。门静脉动脉瘤是门静脉系统的局灶性扩张(2)。通常是在对消化不良的调查中偶然诊断出来的(1)。我们的病例是一名65岁男性。他患有胀气和消化不良2年。他过去的病史很重要,因为19年前,由于交通事故,他的右上腹受到钝性创伤。进行上腹部超声成像以诊断可能的胆石症。门静脉左支近端镰状韧带旁一处静脉动脉瘤,直径28x24mm。(图1和图2)。图1外伤性门静脉动脉瘤2 / 4图2图2彩色多普勒超声成像显示静脉动脉瘤扩张,呈连续血流型,与门静脉血流相似(图3)。
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引用次数: 1
Right ventricle myxoma obstructing partially right ventricular outflow tract 右心室黏液瘤部分阻塞右心室流出道
Pub Date : 2008-12-31 DOI: 10.5580/10f2
A. G. Ciss, O. Diarra, A. Ndiaye, P. A. Dieng, P. S. Ba, M. Ba, S. Beye, O. Kane, I. Diop, M. Ndiaye
A 13-year old female was referred from paediatric department for severe dyspnoea (stage III NYHA), with swelling of the face and the lower limbs. The physical examination revealed bad general health status and a clinical anaemia. There was also an enlargement of the jugular veins and the liver. The heart auscultation allowed a diagnosis of a pulmonary stenosis bruit, which was not varying with the changes of postures. The patient did not present any neuro-endocrine clinical signs or skin problems.The transthoracic echocardiography (TTE) revealed a cardiac tumour mimicking a myxoma was implanted on the antero lateral side of the right ventricular wall with an expansion into the outflow tract. The patient was operated within 48 hours following her admission. On CPB the tumour looking like myxoma was excised through a right atriotomy. The tricuspid valve was normal. Cross clamping time was 15 minutes. The pathological examination showed a myxoma-like tumour with two lobes measuring 4.2 x 2.3 centimeters. The evolution was simple; the post operative TTE check ups were satisfactoryRight ventricular myxoma protruding into the outflow tract is rare and can present with right heart failure. Surgical excision is seldom possible.We emphasize the importance of periodic follow up of this young patient with TEE for early detection of recurrence.
一名13岁女性因严重呼吸困难(III期NYHA)从儿科转介,面部和下肢肿胀。体检显示一般健康状况不佳和临床贫血。颈静脉和肝脏也有肿大。心脏听诊可诊断肺动脉狭窄,且不随体位变化而变化。患者未出现任何神经内分泌临床症状或皮肤问题。经胸超声心动图(TTE)显示一个类似黏液瘤的心脏肿瘤植入右心室壁前外侧,并扩张至流出道。患者入院后48小时内接受手术治疗。在CPB上,通过右心房切开术切除了看起来像粘液瘤的肿瘤。三尖瓣正常。交叉夹持时间15分钟。病理检查为黏液瘤样肿瘤,两叶大小为4.2 x 2.3厘米。进化过程很简单;术后TTE检查令人满意。右心室黏液瘤突入流出道是罕见的,可表现为右心衰。手术切除很少可行。我们强调对这名年轻TEE患者进行定期随访以早期发现复发的重要性。
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引用次数: 1
期刊
The Internet Journal of Thoracic and Cardiovascular Surgery
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