Bronchogenic cysts (BC), occur until gestational 6th weeks from abnormal budding of thrachea. They are generally situated in mediastinum and parenchyma of the lungs. Extrathoracic localizations, although uncommon, are neck, abdomen and subcutaneous areas. Substernal-subcutanous settlement of bronchogenic cysts is reported very rarely in literature. In our case; 15 years old boy suffering only from right sided chest pain. The chest X-ray showed a circular lesion nearby the hilar region of right lung. This case is the rarely place bronchogenic cyst localized on intratoracis area that is away from mediastinum and lung. Its treatment is surgical excision on diagnosis.
{"title":"The Localization Of Bronchogenic Cyst Away From Mediastinum","authors":"G. Fındık, E. Çakır, Doğan Kahraman, S. Kaya","doi":"10.5580/113e","DOIUrl":"https://doi.org/10.5580/113e","url":null,"abstract":"Bronchogenic cysts (BC), occur until gestational 6th weeks from abnormal budding of thrachea. They are generally situated in mediastinum and parenchyma of the lungs. Extrathoracic localizations, although uncommon, are neck, abdomen and subcutaneous areas. Substernal-subcutanous settlement of bronchogenic cysts is reported very rarely in literature. In our case; 15 years old boy suffering only from right sided chest pain. The chest X-ray showed a circular lesion nearby the hilar region of right lung. This case is the rarely place bronchogenic cyst localized on intratoracis area that is away from mediastinum and lung. Its treatment is surgical excision on diagnosis.","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116501623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fuad Jan, Hina Mehboob, R. Qadir, A. Jan, Khalil Kanjwal
Cytomegalovirus (CMV) associated vascular thrombosis is an rare but increasingly reported phenomenon and should be considered in the differential diagnosis of splenic infarction once more common diagnoses, such as endocarditis and lymphoma have been excluded. We present a case of a previously healthy, immunocompetent African American woman with acute CMV infection complicated by vascular thrombosis resulting in splenic infarct.
{"title":"Splenic vascular thrombosis in an immunocompetent host due to Cytomegalovirus Infection.","authors":"Fuad Jan, Hina Mehboob, R. Qadir, A. Jan, Khalil Kanjwal","doi":"10.5580/c16","DOIUrl":"https://doi.org/10.5580/c16","url":null,"abstract":"Cytomegalovirus (CMV) associated vascular thrombosis is an rare but increasingly reported phenomenon and should be considered in the differential diagnosis of splenic infarction once more common diagnoses, such as endocarditis and lymphoma have been excluded. We present a case of a previously healthy, immunocompetent African American woman with acute CMV infection complicated by vascular thrombosis resulting in splenic infarct.","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131767801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND: Mortality due to CAD is increasing at an alarming rate in developing countries and it is going to be the largest killer by 2020. Major risk factors include rapid urbanization, physical inactivity, stressful employment and the personality of an individual, all of which act synergistically resulting in increased CAD rates. Though Indians have less conventional risk factors, they are more susceptible to this disease. The current study was focused on impact of behavioral aspects, lifestyle and physical activity influence on CAD, as these risk factors are not properly established by recent research. AIM: The study was undertaken to evaluate the impact of behavior, lifestyle and physical activity in predicting CAD risk in normolipidaemic acute myocardial infarct patients and to compare the findings with healthy subjects. SETTING & DESIGN: Lipid profile and behavioral aspects and lifestyles were determined in 165 normolipidaemic acute myocardial infarct patients and compared with 165 age/sexmatched controls. MATERIAL & METHODS: Total cholesterol, triglycerides, and HDL-cholesterol were analyzed enzymatically using kits obtained from Randox Laboratories Limited, Crumlin, UK. Plasma LDL-cholesterol was determined from the values of total cholesterol and HDL- cholesterol using the Friedwald's formula. The lifestyle and behavioral aspects of the subjects were determined using pre-tested questionnaires. STATISTICS: The values were expressed as means ± standard deviation (SD) and data from patients and controls were compared using students 't'-test. RESULTS AND CONCLUSION: Lipid profiles were higher in case of patients than with controls .apart from HDL-c levels (p<.001), which were significantly lower in patients (p<.001). Patients had higher serum cholesterol and blood pressure compared to controls in each behavioral assessment parameters. Physical activity was found to be lower in patients compared to controls. Hyperactive, irrelevant thinkers and highly ambitious subjects had higher cholesterol and blood pressure in each category. Mostly the middle socioeconomic class was affected (71%) by AMI. In conclusion, our findings indicated a high prevalence of various behavioral risk factors among the myocardial infarct patients. Remedial measures are needed to minimize future morbidity burden and there by minimizing medical expenses. In regard to the risk factor of smoking, a strict public policy in restricting the behaviour and .cigarette distribution may be considered. Although the Government has taken steps in this regard, it is the individual and community who should reduce the risk factor, especially the high risk groups such as lower social status groups.
{"title":"Behavioral pattern, life style and socio economic status in elderly Normolipidemic Acute Myocardial Infarct Subjects - A case control study from South Asia","authors":"Arun Kumar, R. Sivakanesan, S. Nagtilak","doi":"10.5580/3d7","DOIUrl":"https://doi.org/10.5580/3d7","url":null,"abstract":"BACKGROUND: Mortality due to CAD is increasing at an alarming rate in developing countries and it is going to be the largest killer by 2020. Major risk factors include rapid urbanization, physical inactivity, stressful employment and the personality of an individual, all of which act synergistically resulting in increased CAD rates. Though Indians have less conventional risk factors, they are more susceptible to this disease. The current study was focused on impact of behavioral aspects, lifestyle and physical activity influence on CAD, as these risk factors are not properly established by recent research. AIM: The study was undertaken to evaluate the impact of behavior, lifestyle and physical activity in predicting CAD risk in normolipidaemic acute myocardial infarct patients and to compare the findings with healthy subjects. SETTING & DESIGN: Lipid profile and behavioral aspects and lifestyles were determined in 165 normolipidaemic acute myocardial infarct patients and compared with 165 age/sexmatched controls. MATERIAL & METHODS: Total cholesterol, triglycerides, and HDL-cholesterol were analyzed enzymatically using kits obtained from Randox Laboratories Limited, Crumlin, UK. Plasma LDL-cholesterol was determined from the values of total cholesterol and HDL- cholesterol using the Friedwald's formula. The lifestyle and behavioral aspects of the subjects were determined using pre-tested questionnaires. STATISTICS: The values were expressed as means ± standard deviation (SD) and data from patients and controls were compared using students 't'-test. RESULTS AND CONCLUSION: Lipid profiles were higher in case of patients than with controls .apart from HDL-c levels (p<.001), which were significantly lower in patients (p<.001). Patients had higher serum cholesterol and blood pressure compared to controls in each behavioral assessment parameters. Physical activity was found to be lower in patients compared to controls. Hyperactive, irrelevant thinkers and highly ambitious subjects had higher cholesterol and blood pressure in each category. Mostly the middle socioeconomic class was affected (71%) by AMI. In conclusion, our findings indicated a high prevalence of various behavioral risk factors among the myocardial infarct patients. Remedial measures are needed to minimize future morbidity burden and there by minimizing medical expenses. In regard to the risk factor of smoking, a strict public policy in restricting the behaviour and .cigarette distribution may be considered. Although the Government has taken steps in this regard, it is the individual and community who should reduce the risk factor, especially the high risk groups such as lower social status groups.","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130356933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Group B streptococcal endocarditis following elective abortion is a rare complication seen in patients colonized with Group B Streptococci. Screening and prophylaxis for Group B Streptococci should be considered for all patients undergoing elective abortion.
{"title":"Group B streptococcal tricuspid valve endocarditis after abortion, presenting with septic emboli to the lungs.","authors":"Rehana Qadir, Anjum Ara, Asma Taj","doi":"10.5580/643","DOIUrl":"https://doi.org/10.5580/643","url":null,"abstract":"Group B streptococcal endocarditis following elective abortion is a rare complication seen in patients colonized with Group B Streptococci. Screening and prophylaxis for Group B Streptococci should be considered for all patients undergoing elective abortion.","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115164999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Özbek, U. Yetkin, Kaz m Ergüne, M. Akyuz, smail Yürekli, N. Postac, A. Çall, M. Aksun, A. Gürbüz
Giant cell arteritis(GCA) is a relatively common form of systemic vasculitis. GCA is a systemic vasculitis which involves large and medium sized vessels,and it increases the risk of developing a thoracic aortic aneurysm and it is a rare cause.We describe a case of ascending aortic aneurysm in giant cell arteritis. The treating physician should be vigilant in assessing the patient with GCA for thoracic and abdominal aortic aneurysms that are feared complications of GCA. INTRODUCTION Giant cell arteritis(GCA) is a mediumand large-vessel vasculitis, the most prevalent systemic vasculitis in subjects over age 60. Clinical features are miscellaneous and sometimes misleading. Elevated acute-phase responses, such as a high erythrocyte sedimentation rate and increased levels of C-reactive protein, are important clues to the diagnosis, which is ensured by a positive temporal artery biopsy[1]. Additional vascular manifestations include stroke, aortic aneurysm or dissection, and even aortic rupture[2]. CASE PRESENTATION Our case was a 59-year-old female. Her past medical history was significant for hypertension for 10 years. Moreover, she had been diagnosed as having GCA confirmed with biopsy of superficial temporal artery a year ago. Therefore she had been under steroid therapy since then. She also had an aneurysmal dilation of the ascending aorta (54 mm) which was revealed 3 years ago during investigations for palpitation.In transthoracic echocardiogram ascending aortic aneurysm size was 55mm and she had moderate aortic regurgitation. Cardiac catheterization was performed. Ascending aortic dilation was investigated(Figure 1). Coronary arteries were normal. Department of Rheumatology was consulted for preand postoperative recommendations. Figure 1 Figure 1 She was operated under endotracheal general anesthesia and in supine position.Following a median sternotomy,pericardium was opened longitudinally. Ascending aorta was dilated. Since there was a suitable neck just proximal to brachiocephalic trunk, neither axillary nor femoral cannulation was needed. After heparinization, extracorporeal circulation was established between the venae cavae and the ascending aorta. A cross clamp was placed on aorta and by retrograde continuous isothermic blood Ascending Aortic Aneurysm In Giant Cell Arteritis 2 of 5 cardioplegia from coronary sinus,cardiac arrest was established.Hypothermia was moderate (28oc).A vent was placed via the right superior pulmonary vein.Standard aortotomy was made. There was an aortic segment right proximal to the crossclamp, suitable for distal anastomosis. Aortic valve was explored. There was a calcified verrucous structure of 0.5x0.5 cm on the ventricular aspect of the free edge of the right coronary cusp (Figure 2).
{"title":"Ascending Aortic Aneurysm In Giant Cell Arteritis","authors":"C. Özbek, U. Yetkin, Kaz m Ergüne, M. Akyuz, smail Yürekli, N. Postac, A. Çall, M. Aksun, A. Gürbüz","doi":"10.5580/216e","DOIUrl":"https://doi.org/10.5580/216e","url":null,"abstract":"Giant cell arteritis(GCA) is a relatively common form of systemic vasculitis. GCA is a systemic vasculitis which involves large and medium sized vessels,and it increases the risk of developing a thoracic aortic aneurysm and it is a rare cause.We describe a case of ascending aortic aneurysm in giant cell arteritis. The treating physician should be vigilant in assessing the patient with GCA for thoracic and abdominal aortic aneurysms that are feared complications of GCA. INTRODUCTION Giant cell arteritis(GCA) is a mediumand large-vessel vasculitis, the most prevalent systemic vasculitis in subjects over age 60. Clinical features are miscellaneous and sometimes misleading. Elevated acute-phase responses, such as a high erythrocyte sedimentation rate and increased levels of C-reactive protein, are important clues to the diagnosis, which is ensured by a positive temporal artery biopsy[1]. Additional vascular manifestations include stroke, aortic aneurysm or dissection, and even aortic rupture[2]. CASE PRESENTATION Our case was a 59-year-old female. Her past medical history was significant for hypertension for 10 years. Moreover, she had been diagnosed as having GCA confirmed with biopsy of superficial temporal artery a year ago. Therefore she had been under steroid therapy since then. She also had an aneurysmal dilation of the ascending aorta (54 mm) which was revealed 3 years ago during investigations for palpitation.In transthoracic echocardiogram ascending aortic aneurysm size was 55mm and she had moderate aortic regurgitation. Cardiac catheterization was performed. Ascending aortic dilation was investigated(Figure 1). Coronary arteries were normal. Department of Rheumatology was consulted for preand postoperative recommendations. Figure 1 Figure 1 She was operated under endotracheal general anesthesia and in supine position.Following a median sternotomy,pericardium was opened longitudinally. Ascending aorta was dilated. Since there was a suitable neck just proximal to brachiocephalic trunk, neither axillary nor femoral cannulation was needed. After heparinization, extracorporeal circulation was established between the venae cavae and the ascending aorta. A cross clamp was placed on aorta and by retrograde continuous isothermic blood Ascending Aortic Aneurysm In Giant Cell Arteritis 2 of 5 cardioplegia from coronary sinus,cardiac arrest was established.Hypothermia was moderate (28oc).A vent was placed via the right superior pulmonary vein.Standard aortotomy was made. There was an aortic segment right proximal to the crossclamp, suitable for distal anastomosis. Aortic valve was explored. There was a calcified verrucous structure of 0.5x0.5 cm on the ventricular aspect of the free edge of the right coronary cusp (Figure 2).","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123079257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Komolafe, D. Adeyemi, S. O. Adewole, E. Obuotor
This study assessed the changes in serum lipid profiles of experimentally-induced diabetic Wistar rats with view to elucidate the effects STZ induced diabetes on the serum levels of cholesterol and triglycerides of Wistar rats. Twenty adult Wistar rats were randomly assigned into two groups (A and B) of ten rats each. Group A was the control, while Group B was the STZ treated group. The body weight, blood glucose level and serum lipid profiles were monitored in all the animals for four weeks before the commencement of the experiment and throughout the experimental period. Diabetes mellitus was experimentally induced in groups B rats by daily intra-peritoneal administration of multiple doses of 40mg/kg streptozotocin dissolved in 0.1M sodium citrate buffer for 5 consecutive days. The control group was given equivalent volume of citrate buffer. The animals were monitored for four weeks after streptozotocin administration. The data obtained were analyzed using descriptive and inferential statistics. The result revealed a significant (P < 0.05) increase in the serum level of total cholesterol, triglyceride, low-density lipoprotein cholesterol, and very low-density lipoprotein cholesterol of diabetic rats when compared with the control rats while a significant decrease in the high-density lipoprotein cholesterol was obtained. The study revealed that induction of diabetes in rats using STZ result in development of hyperlipidemia in these rats.
{"title":"Streptozotocin-Induced Diabetes Alters The Serum Lipid Profiles Of Adult Wistar Rats","authors":"O. Komolafe, D. Adeyemi, S. O. Adewole, E. Obuotor","doi":"10.5580/2251","DOIUrl":"https://doi.org/10.5580/2251","url":null,"abstract":"This study assessed the changes in serum lipid profiles of experimentally-induced diabetic Wistar rats with view to elucidate the effects STZ induced diabetes on the serum levels of cholesterol and triglycerides of Wistar rats. Twenty adult Wistar rats were randomly assigned into two groups (A and B) of ten rats each. Group A was the control, while Group B was the STZ treated group. The body weight, blood glucose level and serum lipid profiles were monitored in all the animals for four weeks before the commencement of the experiment and throughout the experimental period. Diabetes mellitus was experimentally induced in groups B rats by daily intra-peritoneal administration of multiple doses of 40mg/kg streptozotocin dissolved in 0.1M sodium citrate buffer for 5 consecutive days. The control group was given equivalent volume of citrate buffer. The animals were monitored for four weeks after streptozotocin administration. The data obtained were analyzed using descriptive and inferential statistics. The result revealed a significant (P < 0.05) increase in the serum level of total cholesterol, triglyceride, low-density lipoprotein cholesterol, and very low-density lipoprotein cholesterol of diabetic rats when compared with the control rats while a significant decrease in the high-density lipoprotein cholesterol was obtained. The study revealed that induction of diabetes in rats using STZ result in development of hyperlipidemia in these rats.","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123986167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Gürbüz, U. Yetkin, Banu Lafç, smail Yürekli, Tevfik Güne
We describe a case of successful repair of symptomatic aortic coarctation with the technique of resection and end-to-end anastomosis in this study.Aortic coarctation is recommended to be relieved by surgery during the ages of 2 and 5 years. Results of surgery are generally good.
{"title":"Successful Repair of Symptomatic Aortic Coarctation With the Technique of Resection and End-to-end Anastomosis","authors":"A. Gürbüz, U. Yetkin, Banu Lafç, smail Yürekli, Tevfik Güne","doi":"10.5580/13b9","DOIUrl":"https://doi.org/10.5580/13b9","url":null,"abstract":"We describe a case of successful repair of symptomatic aortic coarctation with the technique of resection and end-to-end anastomosis in this study.Aortic coarctation is recommended to be relieved by surgery during the ages of 2 and 5 years. Results of surgery are generally good.","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128036175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Meenakshisundaram, P. Thirumalaikolundusubramanian
Background: Abdominal aortic aneurysm (AAA), though it is a deadly disease, it remains silent invariably. Hence, one has to suspect and evaluate AAA at least in a susceptible group at an earlier stage to reduce the morbidity and mortality. Objective: To find out the usefulness and limitations of various biomarkers in diagnosing AAA and drug to prevent/treat it. Material And Methods: Published data were collected from web using keywords biomarkers, clinical methods, screening tests and abdominal aortic aneurysm. Results: Biomarkers identified for AAA are osteopontin (OPN), osetoprotegrin (OPG), Matrix metalloproteinase-9 (MMP-9), circulating levels of tumor necrosis factor-α, interleukin-1β, interleukin -6, interferon-γ, amino terminal propeptide of type 3 collagen, C-reactive protein (CRP), fibrinogen, total WBC count, albumin and ultrasonogram of abdomen. Co-existing illnesses influence inflammatory biomarkers. The promising biomarker is Osteopontin and this is useful to assess the status and progression of AAA. The drug, Irbesartan (angiotensin II blocker) has been shown to reduce the size of aneurysm by dwindling the secretion of osteoprotegrin. Conclusions: Primary focus should be on early detection and management. To achieve this goal, orientation of primary health care professionals towards symptoms and signs of AAA, surgeons to look for the same during abdominal surgeries and radiologists to search for it during USG/ CT scan of abdomen. *This paper was presented in the conference “SUMMIT ON ACUTE AORTIC DISEASES: LUX ET VERITAS” held at Yale University Medical School, New Haven, Connecticut, USA on November 1-2, 2007. This program was conducted by Promedica International CME, a California corporation.
背景:腹主动脉瘤(AAA)是一种致命的疾病，但它总是沉默不语。因此，至少在易感人群中，必须在早期阶段怀疑和评估AAA，以降低发病率和死亡率。目的:探讨各种生物标志物在AAA诊断及预防/治疗方面的应用价值和局限性。材料和方法:使用关键词生物标志物、临床方法、筛选试验和腹主动脉瘤从网上收集已发表的数据。结果:AAA的生物标志物有骨桥蛋白(OPN)、骨蛋白素(OPG)、基质金属蛋白酶-9 (MMP-9)、循环肿瘤坏死因子-α、白细胞介素-1β、白细胞介素-6、干扰素-γ、3型胶原氨基端前肽、c反应蛋白(CRP)、纤维蛋白原、总白细胞计数、白蛋白和腹部超声图。共存的疾病影响炎症生物标志物。最有希望的生物标志物是骨桥蛋白，它有助于评估AAA的状态和进展。厄贝沙坦(血管紧张素II阻滞剂)已被证明可以通过减少骨蛋白素的分泌来缩小动脉瘤的大小。结论:应重视早期发现和早期管理。为了实现这一目标，初级卫生保健专业人员应关注AAA的症状和体征，外科医生应在腹部手术中寻找相同的症状，放射科医生应在腹部USG/ CT扫描中寻找相同的症状。*本文发表于2007年11月1-2日在美国康涅狄格州纽黑文耶鲁大学医学院举行的“急性主动脉疾病峰会:LUX ET VERITAS”会议上。这个项目是由加州公司Promedica International CME实施的。
{"title":"Biomarkers And Screening Tests For Abdominal Aortic Aneurysm: A Brief Review","authors":"R. Meenakshisundaram, P. Thirumalaikolundusubramanian","doi":"10.5580/1913","DOIUrl":"https://doi.org/10.5580/1913","url":null,"abstract":"Background: Abdominal aortic aneurysm (AAA), though it is a deadly disease, it remains silent invariably. Hence, one has to suspect and evaluate AAA at least in a susceptible group at an earlier stage to reduce the morbidity and mortality. Objective: To find out the usefulness and limitations of various biomarkers in diagnosing AAA and drug to prevent/treat it. Material And Methods: Published data were collected from web using keywords biomarkers, clinical methods, screening tests and abdominal aortic aneurysm. Results: Biomarkers identified for AAA are osteopontin (OPN), osetoprotegrin (OPG), Matrix metalloproteinase-9 (MMP-9), circulating levels of tumor necrosis factor-α, interleukin-1β, interleukin -6, interferon-γ, amino terminal propeptide of type 3 collagen, C-reactive protein (CRP), fibrinogen, total WBC count, albumin and ultrasonogram of abdomen. Co-existing illnesses influence inflammatory biomarkers. The promising biomarker is Osteopontin and this is useful to assess the status and progression of AAA. The drug, Irbesartan (angiotensin II blocker) has been shown to reduce the size of aneurysm by dwindling the secretion of osteoprotegrin. Conclusions: Primary focus should be on early detection and management. To achieve this goal, orientation of primary health care professionals towards symptoms and signs of AAA, surgeons to look for the same during abdominal surgeries and radiologists to search for it during USG/ CT scan of abdomen. *This paper was presented in the conference “SUMMIT ON ACUTE AORTIC DISEASES: LUX ET VERITAS” held at Yale University Medical School, New Haven, Connecticut, USA on November 1-2, 2007. This program was conducted by Promedica International CME, a California corporation.","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126950059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Arslan, M. Dumantepe, Mehmet Yılmaz, S. Sanioglu, Kazim Berkoz, A. Ozler
Isolated abdominal aortic dissection is a rare clinical entity. Their anatomic and clinical features are different from those of atherosclerotic aneurysms. Computed tomography scan of the thoracic and abdominal aorta was the main diagnostic tool in all patients. Although natural history and treatment strategies of isolated abdominal aortic dissection have not been well-defined, accurate clinical diagnosis and prompt management are essential to prevent adverse complications. We report here our experience with this rare pathology. The anatomic and clinical features and a review of the literature are also presented.
{"title":"Management of the isolated supraceliac dissection of the abdominal aorta; a case report and review of the literature","authors":"Y. Arslan, M. Dumantepe, Mehmet Yılmaz, S. Sanioglu, Kazim Berkoz, A. Ozler","doi":"10.5580/11","DOIUrl":"https://doi.org/10.5580/11","url":null,"abstract":"Isolated abdominal aortic dissection is a rare clinical entity. Their anatomic and clinical features are different from those of atherosclerotic aneurysms. Computed tomography scan of the thoracic and abdominal aorta was the main diagnostic tool in all patients. Although natural history and treatment strategies of isolated abdominal aortic dissection have not been well-defined, accurate clinical diagnosis and prompt management are essential to prevent adverse complications. We report here our experience with this rare pathology. The anatomic and clinical features and a review of the literature are also presented.","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130766499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
U. Yetkin, M. Kestelli, T. Gunes, M. Bademci, I. Yurekli, A. Gürbüz
Thromboembolism and bleeding rate are higher with mechanical prosthetic heart valves.In this study we discussed the choice of valve prosthesis in an epileptic case with future pregnancy.
机械人工心脏瓣膜的血栓栓塞和出血率较高。在本研究中，我们讨论了在癫痫患者的选择瓣膜假体与未来妊娠。
{"title":"Epilepsy, Future Pregnancy and Choice of Valve Prosthesis","authors":"U. Yetkin, M. Kestelli, T. Gunes, M. Bademci, I. Yurekli, A. Gürbüz","doi":"10.5580/24d8","DOIUrl":"https://doi.org/10.5580/24d8","url":null,"abstract":"Thromboembolism and bleeding rate are higher with mechanical prosthetic heart valves.In this study we discussed the choice of valve prosthesis in an epileptic case with future pregnancy.","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116800398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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