Pub Date : 2022-01-11DOI: 10.5005/jp-journals-10045-00163
Anjala Kumar, Keshavamurthy Lnu, Girish Malvalli
Undescended testis in children is a common condition in a daycare setting. It presents clinically either as palpable or non-palpable, although the former is more common. The two children whom we came across presented with non-palpable testis, were incidentally found to have unilateral hydronephrosis. In both the children, the testis was reported to be in the iliac fossa near the deep inguinal ring on ultrasound. However, the palpation of cord structure with a vaguely palpable flabby scrotal content prompted to do an open orchidopexy in both of them, citing a possibility of a nubbin. During gubernacular dissection, in one child, the vas was found looping beyond the superficial inguinal ring and when traced cranially led to the testis popping out from the deep ring. In the other child, the testis was found in the inguinal canal with vas looping distal to it. It is important at this point to bear in mind this variation to prevent accidentally transecting the vas while dividing the gubernaculum. Highlights: • Anomalies of vas in association with undescended testis are rare and are even rarer with an added hydronephrosis as an association. • This observation has not been reported in the literature so far.
{"title":"Long Loop Vas: A Sinister Association?","authors":"Anjala Kumar, Keshavamurthy Lnu, Girish Malvalli","doi":"10.5005/jp-journals-10045-00163","DOIUrl":"https://doi.org/10.5005/jp-journals-10045-00163","url":null,"abstract":"Undescended testis in children is a common condition in a daycare setting. It presents clinically either as palpable or non-palpable, although the former is more common. The two children whom we came across presented with non-palpable testis, were incidentally found to have unilateral hydronephrosis. In both the children, the testis was reported to be in the iliac fossa near the deep inguinal ring on ultrasound. However, the palpation of cord structure with a vaguely palpable flabby scrotal content prompted to do an open orchidopexy in both of them, citing a possibility of a nubbin. During gubernacular dissection, in one child, the vas was found looping beyond the superficial inguinal ring and when traced cranially led to the testis popping out from the deep ring. In the other child, the testis was found in the inguinal canal with vas looping distal to it. It is important at this point to bear in mind this variation to prevent accidentally transecting the vas while dividing the gubernaculum. Highlights: • Anomalies of vas in association with undescended testis are rare and are even rarer with an added hydronephrosis as an association. • This observation has not been reported in the literature so far.","PeriodicalId":33135,"journal":{"name":"The Iraqi Journal of Medical Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83104209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: High prevalence of both vitamin D (vit. D) deficiency and obesity in world population as reported by many studies drown attention to establish the association and its direction between these two modifiable risk factors and their impact on health status which are still uncertain. Objective: To measure vit. D levels among a sample of obese women, describing some factors that may contribute for vit. D values in this sample and assess the correlation between vit. D levels and body mass index (BMI). Methods: A cross-sectional study was carried out among 100 obese women. Their age ranged between (20-50) years, during the period from 1st February to 1st August 2019. The sample was gathered from laboratory of private medical center at Palestine Street in Baghdad. vit. D was measured by (Ichroma vit D), which is a fluorescence immunoassay. Results: The mean±SD of vit. D values of the participants were found to be (16.05±6.9) ng/ml. Only two women from the sample had sufficient vit. D level of more than 30 ng/ml, (72%) of the participants found to have insufficient vit. D level 10-29.9 ng/ml and the remaining had deficiency in vit. D level <10 ng/ml. A significant association was found between vit. D levels and the age participants and beverages drinking (P≤0.01). Indirect correlation was found between vit. D values of the participants, their BMI values, and waist/ hip ratios and was significant with the last P≤0.012. Conclusion: No association was found between vit. D and BMI, but there is indirect correlation between vit. D and waist/hip ratio. Highest deficiency of vit. D among age group (30-39) years old and among those who were drinking carbonated beverage. Keywords: Obese, women, vitamin D, body mass index Citation: Abdulkader HD, Al-Saffar AJ. Assessment of vitamin D level in a sample of Iraqi obese women. Iraqi JMS. 2021; 19(2): 172-181. doi: 10.22578/IJMS.19.2.6
背景：正如许多研究所报道的那样，维生素D缺乏症和肥胖在世界人口中的高患病率引起了人们的关注，以确定这两个可改变的风险因素之间的联系及其方向，以及它们对健康状况的影响，但这一点仍不确定。目的：测量vit。肥胖女性样本中的D水平，描述了可能导致vit的一些因素。D值，并评估vit之间的相关性。D水平和体重指数（BMI）。方法：对100名肥胖女性进行横断面研究。2019年2月1日至8月1日期间，他们的年龄在（20-50）岁之间。样本是从巴格达巴勒斯坦街私人医疗中心的实验室采集的。vit。D通过（Ichroma vit D）测量，这是一种荧光免疫测定法。结果：vit。参与者的D值为（16.05±6.9）ng/ml。样本中只有两名女性有足够的vit。D水平超过30 ng/ml，（72%）的参与者被发现维生素D不足。D水平为10-29.9 ng/ml，其余为维生素缺乏。D水平<10 ng/ml。vit之间存在显著相关性。维生素D水平与年龄、饮酒量呈正相关（P≤0.01）。参与者的D值、他们的BMI值和腰臀比，最后一次P≤0.012时具有显著性。结论：vit之间无相关性。D和BMI，但vit之间存在间接相关性。D和腰臀比。维生素缺乏最高。D在年龄组（30-39岁）和饮用碳酸饮料的人群中。关键词：肥胖，妇女，维生素D，体重指数引用：Abdulkader HD，Al-Saffar AJ。对伊拉克肥胖妇女样本中维生素D水平的评估。伊拉克JMS。2021年；19（2）：172-181。doi:10.2578/IJMS.19.2.6
{"title":"Assessment of Vitamin D Level in a Sample of Iraqi Obese Women","authors":"Hiba Abdulkader, Atheer J. Al-Saffar","doi":"10.22578/ijms.19.2.6","DOIUrl":"https://doi.org/10.22578/ijms.19.2.6","url":null,"abstract":"Background: High prevalence of both vitamin D (vit. D) deficiency and obesity in world population as reported by many studies drown attention to establish the association and its direction between these two modifiable risk factors and their impact on health status which are still uncertain. Objective: To measure vit. D levels among a sample of obese women, describing some factors that may contribute for vit. D values in this sample and assess the correlation between vit. D levels and body mass index (BMI). Methods: A cross-sectional study was carried out among 100 obese women. Their age ranged between (20-50) years, during the period from 1st February to 1st August 2019. The sample was gathered from laboratory of private medical center at Palestine Street in Baghdad. vit. D was measured by (Ichroma vit D), which is a fluorescence immunoassay. Results: The mean±SD of vit. D values of the participants were found to be (16.05±6.9) ng/ml. Only two women from the sample had sufficient vit. D level of more than 30 ng/ml, (72%) of the participants found to have insufficient vit. D level 10-29.9 ng/ml and the remaining had deficiency in vit. D level <10 ng/ml. A significant association was found between vit. D levels and the age participants and beverages drinking (P≤0.01). Indirect correlation was found between vit. D values of the participants, their BMI values, and waist/ hip ratios and was significant with the last P≤0.012. Conclusion: No association was found between vit. D and BMI, but there is indirect correlation between vit. D and waist/hip ratio. Highest deficiency of vit. D among age group (30-39) years old and among those who were drinking carbonated beverage. Keywords: Obese, women, vitamin D, body mass index Citation: Abdulkader HD, Al-Saffar AJ. Assessment of vitamin D level in a sample of Iraqi obese women. Iraqi JMS. 2021; 19(2): 172-181. doi: 10.22578/IJMS.19.2.6","PeriodicalId":33135,"journal":{"name":"The Iraqi Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48179190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Chronic lymphocytic leukemia (CLL) is a malignancy of mature B cells. The genetic factors have been found to play a role in the pathogenesis of the disease. Deletions of the long arm of chromosome 13, specifically involving band 13q14 (del(13q14)) constitute the single most frequently observed cytogenetic aberration in CLL, occurring in ~55% of all cases, followed by structural abnormalities of ch 12(trisomy 12), del 11q22.3-q23.1, del 6q21-q23, del 17p13.1, and 14q. Objective: To detect frequencies of chromosome 13q14 deletion, chromosome 11q22 deletion and trisomy 12 in in CLL patients using FISH technique, and to investigate the relation between those chromosomal abnormalities and clinical features and hematological parameters. Methods: This cross-sectional study was conducted on fifty newly diagnosed patients with CLL. Three ml of fresh blood were taken from each patient at admission and then transfer it to FISH unit for blood preparation. Slide preparation was done by using dual color fusion gene probe. The slides were read in the second day by fluorescent microscope. Results: Deleted chromosome 13 was found in 24 out of 50 patients, (48%). Trisomy chromosome 12 was found in 15 out of 50 patients, (30%). Deleted chromosome 11 was found in 12 out of 50 patients, (24%). Conclusion: In a sample of Iraqi adult with CLL, the most frequent chromosomal abnormality was deletion of chromosome 13 followed by trisomy of chromosome 12 and chromosome 11 deletion. Keywords: Chronic lymphocytic leukemia, FISH, deleted chromosome 13, trisomy chromosome 12 Citation: Hashim HH, Abdulateef SS. Detection of chromosome 13q14 deletion, chromosome 11q22 deletion and trisomy 12 in chronic lymphocytic leukemia patients. Iraqi JMS. 2021; 19(2): 213-229. doi: 10.22578/IJMS.19.2.11
{"title":"Detection of Chromosome 13q14 Deletion, Chromosome 11q22 Deletion and Trisomy 12 in Chronic Lymphocytic Leukemia Patients","authors":"Hiba Hashim, S. Abdulateef","doi":"10.22578/ijms.19.2.11","DOIUrl":"https://doi.org/10.22578/ijms.19.2.11","url":null,"abstract":"Background: Chronic lymphocytic leukemia (CLL) is a malignancy of mature B cells. The genetic factors have been found to play a role in the pathogenesis of the disease. Deletions of the long arm of chromosome 13, specifically involving band 13q14 (del(13q14)) constitute the single most frequently observed cytogenetic aberration in CLL, occurring in ~55% of all cases, followed by structural abnormalities of ch 12(trisomy 12), del 11q22.3-q23.1, del 6q21-q23, del 17p13.1, and 14q. Objective: To detect frequencies of chromosome 13q14 deletion, chromosome 11q22 deletion and trisomy 12 in in CLL patients using FISH technique, and to investigate the relation between those chromosomal abnormalities and clinical features and hematological parameters. Methods: This cross-sectional study was conducted on fifty newly diagnosed patients with CLL. Three ml of fresh blood were taken from each patient at admission and then transfer it to FISH unit for blood preparation. Slide preparation was done by using dual color fusion gene probe. The slides were read in the second day by fluorescent microscope. Results: Deleted chromosome 13 was found in 24 out of 50 patients, (48%). Trisomy chromosome 12 was found in 15 out of 50 patients, (30%). Deleted chromosome 11 was found in 12 out of 50 patients, (24%). Conclusion: In a sample of Iraqi adult with CLL, the most frequent chromosomal abnormality was deletion of chromosome 13 followed by trisomy of chromosome 12 and chromosome 11 deletion. Keywords: Chronic lymphocytic leukemia, FISH, deleted chromosome 13, trisomy chromosome 12 Citation: Hashim HH, Abdulateef SS. Detection of chromosome 13q14 deletion, chromosome 11q22 deletion and trisomy 12 in chronic lymphocytic leukemia patients. Iraqi JMS. 2021; 19(2): 213-229. doi: 10.22578/IJMS.19.2.11","PeriodicalId":33135,"journal":{"name":"The Iraqi Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45612427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: It is known that measurement of serum total sialic acid (TSA), lipid bound sialic acid (LBSA) and L-Fucose levels may be altered and associated with different types of disease included malignant tumors, therefore, the evaluation of these compounds in serum cancer patients may elucidate the possibility of using this as a diagnostic marker. Objective: To explore the clinical application of TSA, LBSA and L-Fucose serum levels in patients with different site of nasal and para nasal sinus malignancies and compare with a group of healthy controls. Methods: Blood samples obtained from 16 patients with nasal-paranasal sinus malignancies confirmed cases (12 males, 4 females) (age range 45-73 years) and 28 healthy individuals (18 males, 10 females) (age range 38-67 years) participated in this study. Serum TSA and LBSA levels were determined by using colorimetric methods and the serum Fucose level estimation was done based on the method as adopted by Winzler using cysteine reagent. Results: Results showed that serum levels of TSA, LBSA and L-Fucose were significantly higher in cancer patients compared to normal healthy control (P<0.001) and more increased in patients with ethmoid and frontal sinuses cancer group. Conclusion: Estimation of TSA, LBSA and L-Fucose is suggestive to be a reliable marker as well as can use an effective diagnostic biomarker of cancer patients. Keywords: Sialic acid, lipid-bound sialic acid, Fucose, nasal, paranasal sinus cancer, spectrophotometer Citation: Mohammed AK, Mahdi NR, Ahmed FS. Biochemical estimation of total sialic acid, lipid-bound sialic acid and fucose in serum patients with nasal and paranasal sinus malignancies. Iraqi JMS. 2021; 19(2): 137-146. doi: 10.22578/IJMS.19.2.2
{"title":"Biochemical Estimation of Total Sialic Acid, Lipid-Bound Sialic Acid and Fucose in Serum Patients with Nasal and Paranasal Sinus Malignancies","authors":"A. Mohammed, Nidal Mahdi, F. Ahmed","doi":"10.22578/ijms.19.2.2","DOIUrl":"https://doi.org/10.22578/ijms.19.2.2","url":null,"abstract":"Background: It is known that measurement of serum total sialic acid (TSA), lipid bound sialic acid (LBSA) and L-Fucose levels may be altered and associated with different types of disease included malignant tumors, therefore, the evaluation of these compounds in serum cancer patients may elucidate the possibility of using this as a diagnostic marker. Objective: To explore the clinical application of TSA, LBSA and L-Fucose serum levels in patients with different site of nasal and para nasal sinus malignancies and compare with a group of healthy controls. Methods: Blood samples obtained from 16 patients with nasal-paranasal sinus malignancies confirmed cases (12 males, 4 females) (age range 45-73 years) and 28 healthy individuals (18 males, 10 females) (age range 38-67 years) participated in this study. Serum TSA and LBSA levels were determined by using colorimetric methods and the serum Fucose level estimation was done based on the method as adopted by Winzler using cysteine reagent. Results: Results showed that serum levels of TSA, LBSA and L-Fucose were significantly higher in cancer patients compared to normal healthy control (P<0.001) and more increased in patients with ethmoid and frontal sinuses cancer group. Conclusion: Estimation of TSA, LBSA and L-Fucose is suggestive to be a reliable marker as well as can use an effective diagnostic biomarker of cancer patients. Keywords: Sialic acid, lipid-bound sialic acid, Fucose, nasal, paranasal sinus cancer, spectrophotometer Citation: Mohammed AK, Mahdi NR, Ahmed FS. Biochemical estimation of total sialic acid, lipid-bound sialic acid and fucose in serum patients with nasal and paranasal sinus malignancies. Iraqi JMS. 2021; 19(2): 137-146. doi: 10.22578/IJMS.19.2.2","PeriodicalId":33135,"journal":{"name":"The Iraqi Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47170079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-30DOI: 10.5005/jp-journals-10045-00158
Jinsa Nizam, S. Manjunath, G. Vidya, Chandrakala Lnu
Ab s t r Ac t Introduction: Brick-kiln workers suffer from high morbidity because of their work. This demands urgent attention to the health and safety of brick-kiln workers. Very limited data on the occupational health status of brick-kiln workers are available in Karnataka. The study was primarily focused on detecting the evidence regarding the occupational hazards among brick factory workers and designing and developing better strategies for improving the working conditions of workers engaged in kilns. Materials and methods: A total of 124 workers with at least a year of experience were included in the study. The data were collected through face-to-face interviews using a semi-structured pretested questionnaire. The information on the demography, their personal habits such as smoking, alcohol consumption, occupational exposure history, and health-seeking behavior. Specific questions/symptoms were asked on the effects of exposure to dust and other particles such as eye irritation, upper respiratory tract irritation, headache, and excessive fatigue. They were subjected to general physical examination and the basic parameters of height, weight, and blood pressure were recorded. Results: Forty percent of workers reported health-related problems, out of which 26% of them were referred to higher centers for further check-up and treatment. Thirty-four percent were having multiple joint pains, low backache, and knee pain. Thirty-two percent complained of rhinitislike symptoms mainly due exposure to cement and other dust particles due to occupational exposure. The rest of the workers complained of bilateral leg pain, gastric irritation, chest pain on exertion, visual disturbances, and difficulty in hearing. Conclusion: Brick kilns need a well-designed comprehensive plan and the necessary resources to prevent work-related illnesses and health risks. This strategy can improve the working conditions and also the productivity of the workers.
{"title":"Evaluation of Occupational Health among Brick Factory Workers","authors":"Jinsa Nizam, S. Manjunath, G. Vidya, Chandrakala Lnu","doi":"10.5005/jp-journals-10045-00158","DOIUrl":"https://doi.org/10.5005/jp-journals-10045-00158","url":null,"abstract":"Ab s t r Ac t Introduction: Brick-kiln workers suffer from high morbidity because of their work. This demands urgent attention to the health and safety of brick-kiln workers. Very limited data on the occupational health status of brick-kiln workers are available in Karnataka. The study was primarily focused on detecting the evidence regarding the occupational hazards among brick factory workers and designing and developing better strategies for improving the working conditions of workers engaged in kilns. Materials and methods: A total of 124 workers with at least a year of experience were included in the study. The data were collected through face-to-face interviews using a semi-structured pretested questionnaire. The information on the demography, their personal habits such as smoking, alcohol consumption, occupational exposure history, and health-seeking behavior. Specific questions/symptoms were asked on the effects of exposure to dust and other particles such as eye irritation, upper respiratory tract irritation, headache, and excessive fatigue. They were subjected to general physical examination and the basic parameters of height, weight, and blood pressure were recorded. Results: Forty percent of workers reported health-related problems, out of which 26% of them were referred to higher centers for further check-up and treatment. Thirty-four percent were having multiple joint pains, low backache, and knee pain. Thirty-two percent complained of rhinitislike symptoms mainly due exposure to cement and other dust particles due to occupational exposure. The rest of the workers complained of bilateral leg pain, gastric irritation, chest pain on exertion, visual disturbances, and difficulty in hearing. Conclusion: Brick kilns need a well-designed comprehensive plan and the necessary resources to prevent work-related illnesses and health risks. This strategy can improve the working conditions and also the productivity of the workers.","PeriodicalId":33135,"journal":{"name":"The Iraqi Journal of Medical Sciences","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81772421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-30DOI: 10.5005/jp-journals-10045-00159
A. Halder, B. Dastidar, S. Gulshan, A. Sarkar
Ab s t r Ac t Introduction: Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome resulting from the immunological hyperactivation of macrophages. The condition can be triggered by an infection, malignancy, or autoimmune disease. Though the current literatures demonstrated a significant portion of sepsis patients are probably suffering from HLH. Case description: Here, we present a case who presented like features of gram-negative sepsis but prompt diagnosis of HLH and treatment saved the patient’s life. Conclusion: Hemophagocytic lymphohistiocytosis should be anticipated and recognized in fulminating sepsis-like conditions and promptly treated with steroids.
{"title":"Uncommon Presentation of a Common Infection","authors":"A. Halder, B. Dastidar, S. Gulshan, A. Sarkar","doi":"10.5005/jp-journals-10045-00159","DOIUrl":"https://doi.org/10.5005/jp-journals-10045-00159","url":null,"abstract":"Ab s t r Ac t Introduction: Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome resulting from the immunological hyperactivation of macrophages. The condition can be triggered by an infection, malignancy, or autoimmune disease. Though the current literatures demonstrated a significant portion of sepsis patients are probably suffering from HLH. Case description: Here, we present a case who presented like features of gram-negative sepsis but prompt diagnosis of HLH and treatment saved the patient’s life. Conclusion: Hemophagocytic lymphohistiocytosis should be anticipated and recognized in fulminating sepsis-like conditions and promptly treated with steroids.","PeriodicalId":33135,"journal":{"name":"The Iraqi Journal of Medical Sciences","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89622806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diabetes is Reversible – A Reality","authors":"Dr.M.Kameswara Rao","doi":"10.5005/jmeds-6-4-iv","DOIUrl":"https://doi.org/10.5005/jmeds-6-4-iv","url":null,"abstract":"","PeriodicalId":33135,"journal":{"name":"The Iraqi Journal of Medical Sciences","volume":"177 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76432247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-30DOI: 10.5005/jp-journals-10045-00161
S. Santhosh, Srinivas M Prasad, M. Shreyas, M. Prakash
We describe a case of rhino-sinosal mucormycosis in a CAT-B coronavirus disease-2019 (COVID-19) patient who developed an AKI, 2 weeks following her recovery from COVID-19. The case report explores the impact of appropriate fluid balance on the treatment of AKI in a patient receiving Inj amphotericin B for the management of rhino-sinosal mucormycosis which she contracted during her COVID-19 infection.
{"title":"Management of AKI in Rhino-sinosal Mucormycosis Treated with Amphotericin B","authors":"S. Santhosh, Srinivas M Prasad, M. Shreyas, M. Prakash","doi":"10.5005/jp-journals-10045-00161","DOIUrl":"https://doi.org/10.5005/jp-journals-10045-00161","url":null,"abstract":"We describe a case of rhino-sinosal mucormycosis in a CAT-B coronavirus disease-2019 (COVID-19) patient who developed an AKI, 2 weeks following her recovery from COVID-19. The case report explores the impact of appropriate fluid balance on the treatment of AKI in a patient receiving Inj amphotericin B for the management of rhino-sinosal mucormycosis which she contracted during her COVID-19 infection.","PeriodicalId":33135,"journal":{"name":"The Iraqi Journal of Medical Sciences","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81840512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-30DOI: 10.5005/jp-journals-10045-00160
M. B. Patil, Sagar P Kabadi
Introduction: Diabetes mellitus (DM) is one of the major public health issues facing the world in the 21st century, WHO estimates > 425 million people have DM worldwide, India having second highest, i.e., 72.9 million. The link of vitamin D with abnormal glucose metabolism gained more scientific attention in the last decade. Globally one in six adults is obese and nearly 2.8 million die each year due to obesity. Obesity and DM are chronic diseases harming human health. Studies demonstrate vitamin D deficiency is closely related to obesity and increased risk of DM. Aims and objectives: To study the clinical profile of newly-detected-type-II-DM patients in relation to vitamin D levels. Correlation of vitamin D levels with BMI in newly-detected-type-II-DM patients. Materials and methods: This is a cross-sectional observational study done over 1 year, among 150 newly-detected-type-II-DM patients, in RRMCH. Informed consent was taken and detailed history, physical examination was done. All patients were submitted for investigations like FBS, PPBS, HbA1c, and vitamin D levels. Results: The mean age was 49.17 ± 12.72. One hundred and eleven (74%) of them had vitamin D levels < 30 ng/dL. Mean vitamin D levels were 24.24 ± 11.20. Mean HbA1c was 10.96 ± 1.78, 9.66 ± 1.37, and 7.05 ± 0.65, among patients having their vitamin D levels ranging < 20, 20–30, and > 30 ng/dL, respectively, showing p value < 0.001. Mean BMI was 29.90 ± 2.18, of 111 of them who had vitamin D levels < 30 ng/dL, 74 of them had BMI (18.5–22.9), 20 had BMI (23–24.9), and 17 of them had BMI > 25. Interpretation and conclusion: In our study, we found that the higher the HbA1c levels, the lower was the vitamin D levels suggesting a good correlation between poor glycemic control and low vitamin D levels. Also, BMI showed moderate correlation to vitamin D levels. Thus, we can conclude that vitamin D levels can be independent risk factors for the development of DM and obesity and hence must be treated promptly. The Journal of Medical Sciences (2020):
{"title":"Clinical Study on Newly Detected Type II Diabetes Mellitus Patients with Special Reference to Serum Vitamin D Levels and Obesity","authors":"M. B. Patil, Sagar P Kabadi","doi":"10.5005/jp-journals-10045-00160","DOIUrl":"https://doi.org/10.5005/jp-journals-10045-00160","url":null,"abstract":"Introduction: Diabetes mellitus (DM) is one of the major public health issues facing the world in the 21st century, WHO estimates > 425 million people have DM worldwide, India having second highest, i.e., 72.9 million. The link of vitamin D with abnormal glucose metabolism gained more scientific attention in the last decade. Globally one in six adults is obese and nearly 2.8 million die each year due to obesity. Obesity and DM are chronic diseases harming human health. Studies demonstrate vitamin D deficiency is closely related to obesity and increased risk of DM. Aims and objectives: To study the clinical profile of newly-detected-type-II-DM patients in relation to vitamin D levels. Correlation of vitamin D levels with BMI in newly-detected-type-II-DM patients. Materials and methods: This is a cross-sectional observational study done over 1 year, among 150 newly-detected-type-II-DM patients, in RRMCH. Informed consent was taken and detailed history, physical examination was done. All patients were submitted for investigations like FBS, PPBS, HbA1c, and vitamin D levels. Results: The mean age was 49.17 ± 12.72. One hundred and eleven (74%) of them had vitamin D levels < 30 ng/dL. Mean vitamin D levels were 24.24 ± 11.20. Mean HbA1c was 10.96 ± 1.78, 9.66 ± 1.37, and 7.05 ± 0.65, among patients having their vitamin D levels ranging < 20, 20–30, and > 30 ng/dL, respectively, showing p value < 0.001. Mean BMI was 29.90 ± 2.18, of 111 of them who had vitamin D levels < 30 ng/dL, 74 of them had BMI (18.5–22.9), 20 had BMI (23–24.9), and 17 of them had BMI > 25. Interpretation and conclusion: In our study, we found that the higher the HbA1c levels, the lower was the vitamin D levels suggesting a good correlation between poor glycemic control and low vitamin D levels. Also, BMI showed moderate correlation to vitamin D levels. Thus, we can conclude that vitamin D levels can be independent risk factors for the development of DM and obesity and hence must be treated promptly. The Journal of Medical Sciences (2020):","PeriodicalId":33135,"journal":{"name":"The Iraqi Journal of Medical Sciences","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85755694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-29DOI: 10.5005/jp-journals-10045-00156
Arpit Mago
Ab s t r Ac t Introduction: Mucoepidermoid carcinoma represents about 15% of salivary gland tumors. They occur mainly in the parotids (60–70%) but they account for a large fraction of salivary gland tumors in the minor salivary glands. Overall they are the most common form of primary malignant tumor of the salivary glands. Our report exemplifies the need to evaluate swellings of the neck region meticulously as it might not be just an inflammatory swelling but an indication of malignancy. Case report: A 36-year-old male patient was referred to our hospital for evaluation of a swelling in the upper neck which gradually progressed over a span of 3 months. It was painless, firm in consistency, and ovoid in shape. The blood and urine investigations were normal. Fine needle aspiration cytology (FNAC) was performed and the findings were correlated with IHC and the mass was confirmed to be a mucoepidermoid carcinoma. Discussion: Mucoepidermoid carcinomas show variability in their behavior. The prognosis is dependent on the clinical stage, site, grading. Duration before diagnosis ranges from months to years. The cure is possible in low and intermediate grades of tumors. Characteristically, it shows t[11;19][q21;p13] with MET1–MAML2 fusion in other cases it occurred in the parotid gland and palate. This is probably the first case reported to occur in a submandibular gland in a patient in the third decade of his life, with its incidence normally common in the 5th to 6th decade.
{"title":"Mucoepidermoid Carcinoma: Presentation at an Uncommon Site","authors":"Arpit Mago","doi":"10.5005/jp-journals-10045-00156","DOIUrl":"https://doi.org/10.5005/jp-journals-10045-00156","url":null,"abstract":"Ab s t r Ac t Introduction: Mucoepidermoid carcinoma represents about 15% of salivary gland tumors. They occur mainly in the parotids (60–70%) but they account for a large fraction of salivary gland tumors in the minor salivary glands. Overall they are the most common form of primary malignant tumor of the salivary glands. Our report exemplifies the need to evaluate swellings of the neck region meticulously as it might not be just an inflammatory swelling but an indication of malignancy. Case report: A 36-year-old male patient was referred to our hospital for evaluation of a swelling in the upper neck which gradually progressed over a span of 3 months. It was painless, firm in consistency, and ovoid in shape. The blood and urine investigations were normal. Fine needle aspiration cytology (FNAC) was performed and the findings were correlated with IHC and the mass was confirmed to be a mucoepidermoid carcinoma. Discussion: Mucoepidermoid carcinomas show variability in their behavior. The prognosis is dependent on the clinical stage, site, grading. Duration before diagnosis ranges from months to years. The cure is possible in low and intermediate grades of tumors. Characteristically, it shows t[11;19][q21;p13] with MET1–MAML2 fusion in other cases it occurred in the parotid gland and palate. This is probably the first case reported to occur in a submandibular gland in a patient in the third decade of his life, with its incidence normally common in the 5th to 6th decade.","PeriodicalId":33135,"journal":{"name":"The Iraqi Journal of Medical Sciences","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85406396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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