Pub Date : 2021-09-18DOI: 10.18502/ijdo.v13i3.7189
Javad Ardeshirpey, A. Bakhshayesh, M. Dehghan, H. Zareei Mahmood Abadi
Objective: Type 2 diabetes (T2DM) is a chronic disease associated with many psychological complications, which require psychological interventions. This study aimed to examine the effect of mindfulness-based cognitive therapy (MBCT) on cognitive emotion regulation, perseverative thinking, and glycemic index in patients with T2DM Materials and Methods: This quasi-experimental study was done on T2DM patients visiting Yazd diabetes center in 2019, 30 men and women were randomly divided into experimental (n=15) and control (n=15) groups. The experimental group received 8 sessions (90 minutes) of MBCT and the control group received no interventions. In the pretest and posttest phase, data were collected using the cognitive emotion regulation questionnaire (CERQ), Perseverative Thinking Questionnaire and fasting blood sugar test. Data were analyzed in statistical package (SPSS 21) using multivariate analysis of covariance. Results: Results showed a significant difference in mean scores of cognitive emotion regulation (F= 9.866 & P-value= 0.0001), perseverative thinking (F= 13.745 & P-value= 0.0001), and fasting blood sugar (FBS) (F= 3.679 & P-value= 0.034) in the experimental group before and after the intervention. Conclusion: Based on findings of the study MBCT by specialists in public and private centers can help improve cognitive emotion regulation strategies, perseverative thinking, and ultimately blood sugar control in patients with T2DM.
{"title":"Effect of Mindfulness-Based Cognitive Therapy on Cognitive Emotion Regulation, Perseverative Thinking, and Glycemic Index in Patients with Type 2 Diabetes- A Trial Study","authors":"Javad Ardeshirpey, A. Bakhshayesh, M. Dehghan, H. Zareei Mahmood Abadi","doi":"10.18502/ijdo.v13i3.7189","DOIUrl":"https://doi.org/10.18502/ijdo.v13i3.7189","url":null,"abstract":"Objective: Type 2 diabetes (T2DM) is a chronic disease associated with many psychological complications, which require psychological interventions. This study aimed to examine the effect of mindfulness-based cognitive therapy (MBCT) on cognitive emotion regulation, perseverative thinking, and glycemic index in patients with T2DM \u0000Materials and Methods: This quasi-experimental study was done on T2DM patients visiting Yazd diabetes center in 2019, 30 men and women were randomly divided into experimental (n=15) and control (n=15) groups. The experimental group received 8 sessions (90 minutes) of MBCT and the control group received no interventions. In the pretest and posttest phase, data were collected using the cognitive emotion regulation questionnaire (CERQ), Perseverative Thinking Questionnaire and fasting blood sugar test. Data were analyzed in statistical package (SPSS 21) using multivariate analysis of covariance. \u0000Results: Results showed a significant difference in mean scores of cognitive emotion regulation (F= 9.866 & P-value= 0.0001), perseverative thinking (F= 13.745 & P-value= 0.0001), and fasting blood sugar (FBS) (F= 3.679 & P-value= 0.034) in the experimental group before and after the intervention. \u0000Conclusion: Based on findings of the study MBCT by specialists in public and private centers can help improve cognitive emotion regulation strategies, perseverative thinking, and ultimately blood sugar control in patients with T2DM.","PeriodicalId":33205,"journal":{"name":"Iranian Journal of Diabetes and Obesity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47333798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-10DOI: 10.18502/ijdo.v13i3.7191
A. Dehghan, Pravin Farzanegi, Hajar Abbaszadeh
Objective: Diabetes mellitus (DM) is the most frequent type of metabolic disorder. Here, we evaluated the effect of continuous and interval training on glycogen storage of gastrocnemius muscle and serum levels of tumor necrosis factor-α (TNF-α) and Interleukin-6 (IL-6) in diabetic rats. Materials and Methods: This study was experimental. 28 rats were randomly divided into four groups. The interval training included 10 sets of one-minute activity with 50% intensity and continuing training included 8 weeks running at the speed of 15 to 28 m/min. Serum levels of IL-6 and TNF-α and glycogen storage of gastrocnemius muscle were measured using specific ELISA Kits. SPSS 23 software was used. Results: The level of fast blood glucose and TNF-α in diabetic+continuous training and diabetic+interval training groups were significantly lower than the control-diabetic group (P-value< 0.0001). In return, the level of Insulin, IL-6, and glycogen storage in diabetic+continuous training and diabetic+interval training groups were significantly higher than the control-diabetic group (P-value< 0.0001). There was a significant difference in value of glycogen storage between diabetic+continuous training and diabetic+interval training groups (P-value< 0.0001). Conclusion: Continuous and interval exercises significantly decreased the levels of these inflammatory mediators in the diabetic rats which were subsequently associated with a significant decrease of blood glucose, insulin tolerance, and improvement of glycogen contents. Both interval and continuous exercises made significant changes, but interval exercises had better effects than continuous exercises.
{"title":"The Effect of Continuous and Interval Training on Glycogen Storage of Gastrocnemius Muscle and Serum Levels of Tumor Necrosis Factor-α & Interleukin-6 in Diabetic Rats","authors":"A. Dehghan, Pravin Farzanegi, Hajar Abbaszadeh","doi":"10.18502/ijdo.v13i3.7191","DOIUrl":"https://doi.org/10.18502/ijdo.v13i3.7191","url":null,"abstract":"Objective: Diabetes mellitus (DM) is the most frequent type of metabolic disorder. Here, we evaluated the effect of continuous and interval training on glycogen storage of gastrocnemius muscle and serum levels of tumor necrosis factor-α (TNF-α) and Interleukin-6 (IL-6) in diabetic rats. \u0000Materials and Methods: This study was experimental. 28 rats were randomly divided into four groups. The interval training included 10 sets of one-minute activity with 50% intensity and continuing training included 8 weeks running at the speed of 15 to 28 m/min. Serum levels of IL-6 and TNF-α and glycogen storage of gastrocnemius muscle were measured using specific ELISA Kits. SPSS 23 software was used. \u0000Results: The level of fast blood glucose and TNF-α in diabetic+continuous training and diabetic+interval training groups were significantly lower than the control-diabetic group (P-value< 0.0001). In return, the level of Insulin, IL-6, and glycogen storage in diabetic+continuous training and diabetic+interval training groups were significantly higher than the control-diabetic group (P-value< 0.0001). There was a significant difference in value of glycogen storage between diabetic+continuous training and diabetic+interval training groups (P-value< 0.0001). \u0000Conclusion: Continuous and interval exercises significantly decreased the levels of these inflammatory mediators in the diabetic rats which were subsequently associated with a significant decrease of blood glucose, insulin tolerance, and improvement of glycogen contents. Both interval and continuous exercises made significant changes, but interval exercises had better effects than continuous exercises.","PeriodicalId":33205,"journal":{"name":"Iranian Journal of Diabetes and Obesity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42985806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-10DOI: 10.18502/ijdo.v13i3.7184
M. Emuze, T. Azeez, A. Esan, J. Adeleye, W. Balogun, T. Akande
Objective: Diabetic foot ulcer (DFU) is a relatively common complication of diabetes mellitus and constitutes a major cause of mortality. This study aimed to assess the knowledge of risk factors for foot ulceration among patients with diabetes in a tertiary health facility in South Western Nigeria. Materials and Methods: This cross-sectional study was initiated with participation of 100 diabetic patients. Diabetic patients were attending the medical outpatient clinic of the University College Hospital, Ibadan. A structured and validated questionnaire was administered and data was analyzed using SPSS 22. Association between sociodemographic characteristics and knowledge of risk factors for foot ulceration was evaluated by chi-square test. Results: Most of respondents were female (66%). The mean age of the patients was 58.77 (±11.8) years and 51% of patients did not know that it is possible to develop foot ulcer without feeling pain and 30% did not know that features suggestive of neuropathy could be associated with development of foot ulcer. 75% did not know that surgical vascular repair could play any role in the healing of a diabetic foot ulcer. 11% of patients were walking barefooted at home and as much as 63% of respondents did not know that poor longterm glycemic control could be a risk factor for the development of diabetic foot ulcers. Conclusion: The knowledge of the patients attending the diabetes clinic of a tertiary hospital in south-western Nigeria on foot care is generally poor. Education in this direction is very paramount to correct this defect.
{"title":"Knowledge of Risk Factors for Foot Ulceration among Patients with Diabetes Mellitus Attending a Tertiary Health Facility in Nigeria","authors":"M. Emuze, T. Azeez, A. Esan, J. Adeleye, W. Balogun, T. Akande","doi":"10.18502/ijdo.v13i3.7184","DOIUrl":"https://doi.org/10.18502/ijdo.v13i3.7184","url":null,"abstract":"Objective: Diabetic foot ulcer (DFU) is a relatively common complication of diabetes mellitus and constitutes a major cause of mortality. This study aimed to assess the knowledge of risk factors for foot ulceration among patients with diabetes in a tertiary health facility in South Western Nigeria. \u0000Materials and Methods: This cross-sectional study was initiated with participation of 100 diabetic patients. Diabetic patients were attending the medical outpatient clinic of the University College Hospital, Ibadan. A structured and validated questionnaire was administered and data was analyzed using SPSS 22. Association between sociodemographic characteristics and knowledge of risk factors for foot ulceration was evaluated by chi-square test. \u0000Results: Most of respondents were female (66%). The mean age of the patients was 58.77 (±11.8) years and 51% of patients did not know that it is possible to develop foot ulcer without feeling pain and 30% did not know that features suggestive of neuropathy could be associated with development of foot ulcer. 75% did not know that surgical vascular repair could play any role in the healing of a diabetic foot ulcer. 11% of patients were walking barefooted at home and as much as 63% of respondents did not know that poor longterm glycemic control could be a risk factor for the development of diabetic foot ulcers. \u0000Conclusion: The knowledge of the patients attending the diabetes clinic of a tertiary hospital in south-western Nigeria on foot care is generally poor. Education in this direction is very paramount to correct this defect.","PeriodicalId":33205,"journal":{"name":"Iranian Journal of Diabetes and Obesity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46004852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-10DOI: 10.18502/ijdo.v13i3.7183
M. Lorenzo, S. Mascolo, Antonio Romanelli
Objective: This study analyses the patients' factors can influence the attitude to follow or not the therapeutic weight-loss plan after national lockdown measures adopted from March 2020 to May 2020. Materials and Methods: Patients that visited a private nutritional center in March 2020 were included in this retrospective observational study. All relevant characteristics were noted. In May 2020, patients who did not attend the follow-up visit were labeled as "abandoned". Variation in Body Mass Index (BMI) was noted in the second visit. Univariate logistic regression was performed to test the influence on dependent variables (lost follow-up). Odds Ratio (OR) was calculated. According to BMI distribution, we performed a Student T-test (α= 0.05) or Wilcoxon test (α= 0.05) to test BMI variation in patients that attended the follow-up visit. A P-value< 0.05 was considered statistically significant. Results: Our population consisted of 77 patients, and 26 patients (33.8%, CI95% 23.4-45.4%) were labelled as "abandoned". Age≥ 54 years old (OR= 8.9048, CI95%:1.888-41.9822, P-value= 0.0057) and suffering from hypertension (OR= 4.8706, CI95%:1.4284-16.6076, Pvalue= 0.0114) were factors associated with the abandon follow-up visits. Wilcoxon test for BMI variation resulted statistically significant (May BMI 29.5 kg/m2 vs March BMI 29.4 kg/m2 , Pvalue= 0.0094). Conclusion: Age and hypertension are related to the risk of abandoning healthcare services after ending the national lockdown. The losing follow-up phenomenon could worsen clinical conditions and reduce life expectancy. An increase in BMI during lockdown should be interpreted as a personal difficulty in complying with therapeutic prescriptions.
{"title":"Impact of COVID-19 Pandemic and Lockdown Measures on the Nutrition Plan Service Cohort","authors":"M. Lorenzo, S. Mascolo, Antonio Romanelli","doi":"10.18502/ijdo.v13i3.7183","DOIUrl":"https://doi.org/10.18502/ijdo.v13i3.7183","url":null,"abstract":"Objective: This study analyses the patients' factors can influence the attitude to follow or not the therapeutic weight-loss plan after national lockdown measures adopted from March 2020 to May 2020. \u0000Materials and Methods: Patients that visited a private nutritional center in March 2020 were included in this retrospective observational study. All relevant characteristics were noted. In May 2020, patients who did not attend the follow-up visit were labeled as \"abandoned\". Variation in Body Mass Index (BMI) was noted in the second visit. Univariate logistic regression was performed to test the influence on dependent variables (lost follow-up). Odds Ratio (OR) was calculated. According to BMI distribution, we performed a Student T-test (α= 0.05) or Wilcoxon test (α= 0.05) to test BMI variation in patients that attended the follow-up visit. A P-value< 0.05 was considered statistically significant. \u0000Results: Our population consisted of 77 patients, and 26 patients (33.8%, CI95% 23.4-45.4%) were labelled as \"abandoned\". Age≥ 54 years old (OR= 8.9048, CI95%:1.888-41.9822, P-value= 0.0057) and suffering from hypertension (OR= 4.8706, CI95%:1.4284-16.6076, Pvalue= 0.0114) were factors associated with the abandon follow-up visits. Wilcoxon test for BMI variation resulted statistically significant (May BMI 29.5 kg/m2 vs March BMI 29.4 kg/m2 , Pvalue= 0.0094). \u0000Conclusion: Age and hypertension are related to the risk of abandoning healthcare services after ending the national lockdown. The losing follow-up phenomenon could worsen clinical conditions and reduce life expectancy. An increase in BMI during lockdown should be interpreted as a personal difficulty in complying with therapeutic prescriptions.","PeriodicalId":33205,"journal":{"name":"Iranian Journal of Diabetes and Obesity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43030498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-10DOI: 10.18502/ijdo.v13i3.7186
Jafar Shabani, Tazehgol Moradi
Objective: Obesity is related to emotional pressures and psychological disorders. Psychiatric disorders, acute psychological stress, psychological problems, and emotional factors induce obesity. This study aimed to investigate the relationship between scale and subscale of emotional intelligence (EI) and obesity among university students in Golestan province, Iran. Materials and Methods: This is a descriptive study. The sample size contained 358 university students. The research instrument was Bar-On and Parker Emotional Intelligence (EI) Questionnaire. The collected data were analyzed by SPSS 22. Moreover, descriptive statistics, Pearson’s correlation, and multiple regression analyses were also done. Results: There is a direct and inverse relationship between students’ total EI (-0.415) and its subscales including intrapersonal skills (-0.393), interpersonal skills (-0.313), adaptability (-0.359), stress management (-0.383), and general mood (-0.372) with overweight. Conclusion: The results of this research may not only open a new window to assist in achieving successful nutritional diet programs, providing people but it also can pave the way for further research conducted by experts in nutrition, medicine, and psychology. The findings of this study will enhance social public awareness on the side- effects of obesity equipping the public with some counseling to lose weight through using EI for people, especially students suffering from obesity.
{"title":"Exploring the Relationship of Emotional Intelligence and Obesity among University Students","authors":"Jafar Shabani, Tazehgol Moradi","doi":"10.18502/ijdo.v13i3.7186","DOIUrl":"https://doi.org/10.18502/ijdo.v13i3.7186","url":null,"abstract":"Objective: Obesity is related to emotional pressures and psychological disorders. Psychiatric disorders, acute psychological stress, psychological problems, and emotional factors induce obesity. This study aimed to investigate the relationship between scale and subscale of emotional intelligence (EI) and obesity among university students in Golestan province, Iran. \u0000Materials and Methods: This is a descriptive study. The sample size contained 358 university students. The research instrument was Bar-On and Parker Emotional Intelligence (EI) Questionnaire. The collected data were analyzed by SPSS 22. Moreover, descriptive statistics, Pearson’s correlation, and multiple regression analyses were also done. \u0000Results: There is a direct and inverse relationship between students’ total EI (-0.415) and its subscales including intrapersonal skills (-0.393), interpersonal skills (-0.313), adaptability (-0.359), stress management (-0.383), and general mood (-0.372) with overweight. \u0000Conclusion: The results of this research may not only open a new window to assist in achieving successful nutritional diet programs, providing people but it also can pave the way for further research conducted by experts in nutrition, medicine, and psychology. The findings of this study will enhance social public awareness on the side- effects of obesity equipping the public with some counseling to lose weight through using EI for people, especially students suffering from obesity.","PeriodicalId":33205,"journal":{"name":"Iranian Journal of Diabetes and Obesity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45689582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-10DOI: 10.18502/ijdo.v13i3.7188
M. Askari, N. Namiranian, Hassan ali Mahmoudi Kohani, Seied Mohammad Reza Aghaee Meybody, Saeede Khalilzade, Z. Mozafari, Mahbubeh Shariati
Objective: The aim of this study was registration of type 1 diabetes mellitus (T1DM) in Yazd (the first phase of registration). Materials and Methods: This study was a cross-sectional study on the first phase registration of T1DM in Yazd, Iran. Participants in this study included all patients diagnosed with T1DM by an endocrinologist. Data were analyzed by SPSS20 statistical software. Non-parametric tests were used in this study. Median ± Range was used to describe the data. Stata 13 software was used to calculate the confidence interval for the prevalence. Results: Yazd T1DM registry (YT1DMR) was conducted from June 2018 to August 2020. All new and old cases of T1DM were registered. YT1DMR was able to identify 158 T1DM and it registered the data of 128 patients. The age of the participants was between 2.5 - 57 years old. Median ± Range of age in these participants was calculated 17 ± 54.5. In terms of gender, (57.81%, CI= 48.76-66.48) of these patients were male. The prevalence of overweight and obesity in these patients was 17.32 (CI= 11.18- 25.04) and 6.29% (CI= 2.75-12.03), respectively. Conclusion: In the future, all patients with T1DM in Yazd province are expected to enroll in the YT1DMR and be followed up.
{"title":"The First Phase Registration of Type 1 Diabetes in Yazd, Iran","authors":"M. Askari, N. Namiranian, Hassan ali Mahmoudi Kohani, Seied Mohammad Reza Aghaee Meybody, Saeede Khalilzade, Z. Mozafari, Mahbubeh Shariati","doi":"10.18502/ijdo.v13i3.7188","DOIUrl":"https://doi.org/10.18502/ijdo.v13i3.7188","url":null,"abstract":"Objective: The aim of this study was registration of type 1 diabetes mellitus (T1DM) in Yazd (the first phase of registration). \u0000Materials and Methods: This study was a cross-sectional study on the first phase registration of T1DM in Yazd, Iran. Participants in this study included all patients diagnosed with T1DM by an endocrinologist. Data were analyzed by SPSS20 statistical software. Non-parametric tests were used in this study. Median ± Range was used to describe the data. Stata 13 software was used to calculate the confidence interval for the prevalence. \u0000Results: Yazd T1DM registry (YT1DMR) was conducted from June 2018 to August 2020. All new and old cases of T1DM were registered. YT1DMR was able to identify 158 T1DM and it registered the data of 128 patients. The age of the participants was between 2.5 - 57 years old. Median ± Range of age in these participants was calculated 17 ± 54.5. In terms of gender, (57.81%, CI= 48.76-66.48) of these patients were male. The prevalence of overweight and obesity in these patients was 17.32 (CI= 11.18- 25.04) and 6.29% (CI= 2.75-12.03), respectively. \u0000Conclusion: In the future, all patients with T1DM in Yazd province are expected to enroll in the YT1DMR and be followed up.","PeriodicalId":33205,"journal":{"name":"Iranian Journal of Diabetes and Obesity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47627245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-10DOI: 10.18502/ijdo.v13i3.7192
M. Bostani, S. A. Noaein
Objective: Apoptosis of pancreatic beta cells plays an important role in the pathogenesis of type 1 diabetes. the purpose of this study was to investigate the effect of continuous aerobic training on Bax/Bcl-2 ratio in pancreatic tissue of streptozotocin (STZ)-induced diabetic rats. Materials and Methods: A total number of 40 male Wistar rats, were divided into healthy control (HC), healthy trained (HT), diabetic control (DC), and diabetic trained (DT) groups. Diabetes was also induced by a single intraperitoneally injection of STZ (45 mg/kg). the training groups performed the exercise on the treadmill for five consecutive days within six weeks with 10-18 m/min intensity and 10-30 minute duration based on the principle of overload. the pancreatic tissue levels of the Bax and the Bcl-2 proteins were further determined via the ELISA method. The analysis of variance test (ANOVA) with Tukey's post hoc test was used for analyzing the data. Results: The results showed that the induction of diabetes had significantly decreased the levels of Bcl-2 protein and increased the levels of Bax protein and Bax/Bcl-2 ratio in the pancreatic tissue (Pvalue=0.001,Effect Size=0.29). As well, the findings showed that six weeks of aerobic exercise training had significantly increased the levels of Bcl-2 and significantly decreased the levels of Bax and Bax/Bcl-2 ratio in the DT group (P-value=0.012, Effect Size=0.23). Conclusion: According to the results of this study, exercise can be considered an effective strategy to reduce the rate of diabeticinduced apoptosis and control its complications.
{"title":"The Effect of Continuous Aerobic Training on Bax/Bcl2 Ratio in Pancreatic Tissue Diabetic Rats","authors":"M. Bostani, S. A. Noaein","doi":"10.18502/ijdo.v13i3.7192","DOIUrl":"https://doi.org/10.18502/ijdo.v13i3.7192","url":null,"abstract":"Objective: Apoptosis of pancreatic beta cells plays an important role in the pathogenesis of type 1 diabetes. the purpose of this study was to investigate the effect of continuous aerobic training on Bax/Bcl-2 ratio in pancreatic tissue of streptozotocin (STZ)-induced diabetic rats. \u0000Materials and Methods: A total number of 40 male Wistar rats, were divided into healthy control (HC), healthy trained (HT), diabetic control (DC), and diabetic trained (DT) groups. Diabetes was also induced by a single intraperitoneally injection of STZ (45 mg/kg). the training groups performed the exercise on the treadmill for five consecutive days within six weeks with 10-18 m/min intensity and 10-30 minute duration based on the principle of overload. the pancreatic tissue levels of the Bax and the Bcl-2 proteins were further determined via the ELISA method. The analysis of variance test (ANOVA) with Tukey's post hoc test was used for analyzing the data. \u0000Results: The results showed that the induction of diabetes had significantly decreased the levels of Bcl-2 protein and increased the levels of Bax protein and Bax/Bcl-2 ratio in the pancreatic tissue (Pvalue=0.001,Effect Size=0.29). As well, the findings showed that six weeks of aerobic exercise training had significantly increased the levels of Bcl-2 and significantly decreased the levels of Bax and Bax/Bcl-2 ratio in the DT group (P-value=0.012, Effect Size=0.23). \u0000Conclusion: According to the results of this study, exercise can be considered an effective strategy to reduce the rate of diabeticinduced apoptosis and control its complications.","PeriodicalId":33205,"journal":{"name":"Iranian Journal of Diabetes and Obesity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45358209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-21DOI: 10.18502/ijdo.v13i2.6481
M. Dehghan, Zohreh Akhoundimeybodi
Edema is a rare complication induced by insulin therapy, which is mostly developed after initiation or intensification of insulin treatment in diabetic patients. Edema can either be localized or generalized. Our patient was a 34-year-old woman with type 2 diabetes. She was under treatment with oral agents medication, but recently insulin therapy was initiated for her due to inability to control her hyperglycemia and development of diabetic ketoacidosis. The patient referred while suffering from bilateral lower extremity edema. During follow-up, her edema resolved spontaneously without any specific treatments. In this patient, the diagnosis of edema was based on ruling out other causes, along with more accurate blood glucose control during diabetic ketoacidosis process and spontaneous recovery. Based on our finding, it can be concluded that insulininduced edema is not a worrisome problem and in most cases, its symptoms resolve without treatment and through restricting the consumption of water and salt.
{"title":"Insulin Edema in Type 2 Diabetes Mellitus: A Case Report Study","authors":"M. Dehghan, Zohreh Akhoundimeybodi","doi":"10.18502/ijdo.v13i2.6481","DOIUrl":"https://doi.org/10.18502/ijdo.v13i2.6481","url":null,"abstract":"Edema is a rare complication induced by insulin therapy, which is mostly developed after initiation or intensification of insulin treatment in diabetic patients. Edema can either be localized or generalized. Our patient was a 34-year-old woman with type 2 diabetes. She was under treatment with oral agents medication, but recently insulin therapy was initiated for her due to inability to control her hyperglycemia and development of diabetic ketoacidosis. The patient referred while suffering from bilateral lower extremity edema. During follow-up, her edema resolved spontaneously without any specific treatments. In this patient, the diagnosis of edema was based on ruling out other causes, along with more accurate blood glucose control during diabetic ketoacidosis process and spontaneous recovery. Based on our finding, it can be concluded that insulininduced edema is not a worrisome problem and in most cases, its symptoms resolve without treatment and through restricting the consumption of water and salt. \u0000 ","PeriodicalId":33205,"journal":{"name":"Iranian Journal of Diabetes and Obesity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46553566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-10DOI: 10.18502/ijdo.v13i2.6480
S. Imanipour, V. Imanipour
Nonalcoholic fatty liver is known in the general public as an epidemic disease. The purpose of this mini-review was to determine a link between physical education (PA) and the risk of nonalcoholic fatty liver disease (NAFLD) determine the influence of an exercise method (volume and kind of exercise) on being health outcome. Body mass index (BMI) was the good criteria for classifying obesity. It is ranges from underweight (<18.5 kg/m2) to severe or unhealthy obesity (≥40 kg/m2). Most time exercise was sufficient to reduce advanced fibrosis in almost 50% including moderated aerobic exercise for 2.5–5 hours a week, or 1–2.5 hours a week on vigorous intense exercise. Different intensities of physical activity is affected on fatty liver factors and volume and exercise method stimulate improvements in related health outcome measures in obese people. Prolonged inactivity time was increased the prevalence of NAFLD. The final results were shown the influence of PA at different intensities and volume on NAFLD. Then a healthy lifestyle can improve the quality of life and physical health.
{"title":"How is the Effect of Physical Activity on Non-Alcoholic Fatty Liver in Obese People? A Mini Review","authors":"S. Imanipour, V. Imanipour","doi":"10.18502/ijdo.v13i2.6480","DOIUrl":"https://doi.org/10.18502/ijdo.v13i2.6480","url":null,"abstract":"Nonalcoholic fatty liver is known in the general public as an epidemic disease. The purpose of this mini-review was to determine a link between physical education (PA) and the risk of nonalcoholic fatty liver disease (NAFLD) determine the influence of an exercise method (volume and kind of exercise) on being health outcome. Body mass index (BMI) was the good criteria for classifying obesity. It is ranges from underweight (<18.5 kg/m2) to severe or unhealthy obesity (≥40 kg/m2). Most time exercise was sufficient to reduce advanced fibrosis in almost 50% including moderated aerobic exercise for 2.5–5 hours a week, or 1–2.5 hours a week on vigorous intense exercise. Different intensities of physical activity is affected on fatty liver factors and volume and exercise method stimulate improvements in related health outcome measures in obese people. Prolonged inactivity time was increased the prevalence of NAFLD. The final results were shown the influence of PA at different intensities and volume on NAFLD. Then a healthy lifestyle can improve the quality of life and physical health.","PeriodicalId":33205,"journal":{"name":"Iranian Journal of Diabetes and Obesity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48373821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-15DOI: 10.18502/IJDO.V13I1.5747
M. Abdolkarimi, M. Morowatisharifabad, M. Asadpour
iabetes is known as a worldwide health problem, globally 12% of total health costs are attributed to diabetes (1). In Iran, the prevalence of diabetes is increasing, as it is estimated that by the year 2030, the population of diabetes in Iran will D 1. Assistant Professor School of Health, School of Health, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. 2. Professor Department of Health Education & Promotion, Department of Health Education & Promotion, Shahid Sadoughl University of Medical Sciences, Yazd, Iran. 3. Assistant Professor, School of Health, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
{"title":"The Effect of Implementation Intention on Improving Physical Activity Level and Cardiovascular Fitness in Patients with Type 2 Diabetes: A Randomized Control Study","authors":"M. Abdolkarimi, M. Morowatisharifabad, M. Asadpour","doi":"10.18502/IJDO.V13I1.5747","DOIUrl":"https://doi.org/10.18502/IJDO.V13I1.5747","url":null,"abstract":"iabetes is known as a worldwide health problem, globally 12% of total health costs are attributed to diabetes (1). In Iran, the prevalence of diabetes is increasing, as it is estimated that by the year 2030, the population of diabetes in Iran will D 1. Assistant Professor School of Health, School of Health, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. 2. Professor Department of Health Education & Promotion, Department of Health Education & Promotion, Shahid Sadoughl University of Medical Sciences, Yazd, Iran. 3. Assistant Professor, School of Health, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.","PeriodicalId":33205,"journal":{"name":"Iranian Journal of Diabetes and Obesity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45495476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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