Perdarahan intraserebral (PIS) meningkat pada pasien yang memiliki riwayat hipertensi, usia tua, dan berjenis kelamin laki-laki. Tujuan penelitian ini untuk mengetahui karakteristik pasien PIS berdasarkan insidensi, faktor risiko, manifestasi klinis, dan lokasi perdarahan. Penelitian ini menggunakan rancangan cross sectional yang diambil dari rekam medik meliputi usia, jenis kelamin, anamnesis, pemeriksaan fisik, dan hasil CT Scan. Sampel penelitian sejumlah 49 rekam medik. Hasil penelitian menunjukkan insidensi 7,7%, jumlah pasien PIS terbanyak adalah perempuan (51,02%) dengan usia ≥65 tahun (36,73%). Perdarahan di ganglia basalis menyebabkan hemiparese (31,91%), perdarahan di talamus paling sering dengan hemiparese (36,84%), perdarahan batang otak sering dengan aphasia dan hemiparese (26,32%), perdarahan serebelum dengan sakit kepala dan hemiparese (33,33%), sedangkan perdarahan di lobar paling sering dengan hemiparese (36,67%). Pasien dengan hipertensi sebanyak 67,35% dengan 32,65% pasien mengalami krisis hirpertensi. Gejala penurunan kesadaran (31,33%), dan lokasi perdarahan di ganglia basalis (40,82%). Dari hasil tersebut terdapat faktor yang bisa diintervensi atau dicegah terjadinya strok seperti pengelolaan tekanan darah secara optimal yang bisa dilakukan dengan menggiatkan edukasi bagi masyarakat dengan faktor risiko tersebut secara terus menerus. Simpulan dari hasil penelitian ini menunjukkan bahwa PIS merupakan penyakit yang sering menyerang pada perempuan berusia tua yang memiliki riwayat hipertensi. Perdarahan intraserebral paling sering terjadi di ganglia basalis dengan gejala hemiparese dan tekanan darah ≥180/120 mmHg
{"title":"KARAKTERISTIK PASIEN PERDARAHAN INTRASEREBRAL BERDASARKAN FAKTOR RISIKO, KLINIS, DAN LOKASI DI RS DUSTIRA CIMAHI PERIODE 2019-2020","authors":"Andri Kusuma, Anita Liliana, Nabila Asad","doi":"10.35990/mk.v6n1.p1-10","DOIUrl":"https://doi.org/10.35990/mk.v6n1.p1-10","url":null,"abstract":"Perdarahan intraserebral (PIS) meningkat pada pasien yang memiliki riwayat hipertensi, usia tua, dan berjenis kelamin laki-laki. Tujuan penelitian ini untuk mengetahui karakteristik pasien PIS berdasarkan insidensi, faktor risiko, manifestasi klinis, dan lokasi perdarahan. Penelitian ini menggunakan rancangan cross sectional yang diambil dari rekam medik meliputi usia, jenis kelamin, anamnesis, pemeriksaan fisik, dan hasil CT Scan. Sampel penelitian sejumlah 49 rekam medik. Hasil penelitian menunjukkan insidensi 7,7%, jumlah pasien PIS terbanyak adalah perempuan (51,02%) dengan usia ≥65 tahun (36,73%). Perdarahan di ganglia basalis menyebabkan hemiparese (31,91%), perdarahan di talamus paling sering dengan hemiparese (36,84%), perdarahan batang otak sering dengan aphasia dan hemiparese (26,32%), perdarahan serebelum dengan sakit kepala dan hemiparese (33,33%), sedangkan perdarahan di lobar paling sering dengan hemiparese (36,67%). Pasien dengan hipertensi sebanyak 67,35% dengan 32,65% pasien mengalami krisis hirpertensi. Gejala penurunan kesadaran (31,33%), dan lokasi perdarahan di ganglia basalis (40,82%). Dari hasil tersebut terdapat faktor yang bisa diintervensi atau dicegah terjadinya strok seperti pengelolaan tekanan darah secara optimal yang bisa dilakukan dengan menggiatkan edukasi bagi masyarakat dengan faktor risiko tersebut secara terus menerus. Simpulan dari hasil penelitian ini menunjukkan bahwa PIS merupakan penyakit yang sering menyerang pada perempuan berusia tua yang memiliki riwayat hipertensi. Perdarahan intraserebral paling sering terjadi di ganglia basalis dengan gejala hemiparese dan tekanan darah ≥180/120 mmHg","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81579301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hesty Wahyuningsih, A. Aulia, Prima Rizky Nur Rasyid, Ajat Sudrajat, Riefky Ikhsan Pratama
Penyakit jantung koroner (PJK) merupakan penyakit dengan tingkat kematian tinggi. Beberapa kondisi yang menjadi faktor risiko PJK antara lain dislipidemia, diabetes melitus, merokok, dan obesitas. Hiperurisemia diduga mempunyai hubungan dengan kejadian PJK dalam beberapa tahun terakhir, namun masih terdapat kontroversi. Penelitian ini bertujuan untuk mengetahui hubungan antara hiperurisemia dengan PJK di Rumah Sakit Islam Sultan Agung Semarang. Rancangan penelitian yang digunakan adalah studi observasional dengan pendekatan cross sectional. Sampel penelitian berjumlah 102 orang diambil dengan cara consecutive sampling dari pasien hiperurisemia dan nonhiperurisemia di Rumah Sakit Islam Sultan Agung Semarang periode tahun 2016-2020. Data diambil dari catatan rekam medis dan dianalisis menggunakan koefisien kontingensi. Hasil penelitian menunjukkan bahwa pada kelompok hiperurisemia terdapat 39 orang yang menderita PJK (38,24%), sedangkan pada kelompok nonhiperurisemia terdapat 18 orang yang menderita PJK (17,65%). Hasil analisis Contingency Coefficient didapatkan nilai p 0,000 (p<0,05), dengan kekuatan hubungan sebesar 0,383. Kesimpulan yang didapatkan adalah terdapat korelasi antara hiperurisemia dengan PJK dengan kekuatan hubungan yang rendah.
{"title":"HUBUNGAN HIPERURISEMIA DENGAN KEJADIAN PENYAKIT JANTUNG KORONER","authors":"Hesty Wahyuningsih, A. Aulia, Prima Rizky Nur Rasyid, Ajat Sudrajat, Riefky Ikhsan Pratama","doi":"10.35990/mk.v6n1.p56-66","DOIUrl":"https://doi.org/10.35990/mk.v6n1.p56-66","url":null,"abstract":"Penyakit jantung koroner (PJK) merupakan penyakit dengan tingkat kematian tinggi. Beberapa kondisi yang menjadi faktor risiko PJK antara lain dislipidemia, diabetes melitus, merokok, dan obesitas. Hiperurisemia diduga mempunyai hubungan dengan kejadian PJK dalam beberapa tahun terakhir, namun masih terdapat kontroversi. Penelitian ini bertujuan untuk mengetahui hubungan antara hiperurisemia dengan PJK di Rumah Sakit Islam Sultan Agung Semarang. Rancangan penelitian yang digunakan adalah studi observasional dengan pendekatan cross sectional. Sampel penelitian berjumlah 102 orang diambil dengan cara consecutive sampling dari pasien hiperurisemia dan nonhiperurisemia di Rumah Sakit Islam Sultan Agung Semarang periode tahun 2016-2020. Data diambil dari catatan rekam medis dan dianalisis menggunakan koefisien kontingensi. Hasil penelitian menunjukkan bahwa pada kelompok hiperurisemia terdapat 39 orang yang menderita PJK (38,24%), sedangkan pada kelompok nonhiperurisemia terdapat 18 orang yang menderita PJK (17,65%). Hasil analisis Contingency Coefficient didapatkan nilai p 0,000 (p<0,05), dengan kekuatan hubungan sebesar 0,383. Kesimpulan yang didapatkan adalah terdapat korelasi antara hiperurisemia dengan PJK dengan kekuatan hubungan yang rendah.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83116581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"KARAKTERISTIK PASIEN DAN POLA PENGGUNAAN OBAT ANTI BANGKITAN (OAB) PADA PASIEN EPILEPSI DI RS. MUHAMMADIYAH PALEMBANG","authors":"Yesi Astri, Irma Yanti, Ayu Permata Sari","doi":"10.32502/sm.v13i2.4446","DOIUrl":"https://doi.org/10.32502/sm.v13i2.4446","url":null,"abstract":"","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89696414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ANALISIS HUBUNGAN MASA KERJA DAN UMUR TERHADAP ROM AKTIF FLEXI BAHU PADA KULI PANGGUL","authors":"Indriyani Indriyani, Mutia Khairunnisa","doi":"10.32502/sm.v13i2.5689","DOIUrl":"https://doi.org/10.32502/sm.v13i2.5689","url":null,"abstract":"","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87870997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aliyah Ari Juliani, Merry Tiyas Anggraini, Nina Anggraeni Noviasari
{"title":"HUBUNGAN ANTARA TINGKAT SELF CARE DAN FUNGSI KELUARGA TERHADAP KUALITAS HIDUP PENYANDANG DISABILITAS FISIK DI SLB N 1 PEMALANG","authors":"Aliyah Ari Juliani, Merry Tiyas Anggraini, Nina Anggraeni Noviasari","doi":"10.32502/sm.v13i2.4157","DOIUrl":"https://doi.org/10.32502/sm.v13i2.4157","url":null,"abstract":"","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79111665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"LITERATUR REVIEW TENTANG PERSEPSI SOSIAL BUDAYA MASYARAKAT TERHADAP PENYAKIT TUBERCULOSIS PARU","authors":"Rahmi Fitri, Tri Krianto","doi":"10.32502/sm.v13i2.4586","DOIUrl":"https://doi.org/10.32502/sm.v13i2.4586","url":null,"abstract":"","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"84 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82067252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-20DOI: 10.18196/mmjkk.v23i1.16121
Nelly Tolla, Rachmawaty Rachmawaty, Andi Salsa Anggeraini, Darmmawaty R, F. Nur
Hypercoagulation in the alveoli of the lungs is one of the causes of death in SARS-CoV2 virus infection. Hypercoagulation is defined by an elevation in D-Dimer, which typically rises on the fifth day of therapy. This parameter is not available in all hospitals and is still relatively expensive in preventing premature death. Platelets count and indices are suggested to describe the thromboinflammatory condition in COVID-19 patients. This research is an observational analytic study with a cross-sectional study design in 59 COVID-19 patients treated at Hassanuddin University Hospital. The patients who are declared COVID-19 based on the results of radiological examinations and PCR swabs underwent routine blood tests and D-Dimer before undergoing therapy. Data were analyzed using the Spearmen test in SPSS version 26 to reveal the correlation between platelet count, platelet indices, and D Dimer in COVID-19 patients with severe and non-severe conditions. Platelet count, platelet indices, especially MPV, and D-Dimer values were found to correlate in both groups COVID-19 using the Spearman rho correlation test (p 0.000) with strengths correlation between -44.6 and 60.5. There was a significant association between platelet count and MPV value with D-Dimer in COVID-19 patients.
肺泡高凝是SARS-CoV2病毒感染的死亡原因之一。高凝的定义是d -二聚体升高，通常在治疗的第五天升高。并非所有医院都有这一参数，而且在预防过早死亡方面仍然相对昂贵。建议血小板计数和指标来描述COVID-19患者的血栓炎症状况。本研究是一项观察性分析研究，采用横断面研究设计，对在哈桑努丁大学医院治疗的59例COVID-19患者进行了研究。根据放射学检查和PCR拭子结果宣布为COVID-19的患者在接受治疗前进行常规血液检查和d -二聚体检查。采用SPSS version 26中的Spearmen检验分析数据，揭示重症和非重症患者血小板计数、血小板指数与D二聚体的相关性。采用Spearman rho相关检验发现，两组患者的血小板计数、血小板指数(尤其是MPV)和d -二聚体值存在相关性(p 0.000)，相关强度为-44.6和60.5。COVID-19患者血小板计数、MPV值与d -二聚体有显著相关性。
{"title":"Correlation Between Platelets Count, Platelet Index and D-Dimer in Covid-19 Patients","authors":"Nelly Tolla, Rachmawaty Rachmawaty, Andi Salsa Anggeraini, Darmmawaty R, F. Nur","doi":"10.18196/mmjkk.v23i1.16121","DOIUrl":"https://doi.org/10.18196/mmjkk.v23i1.16121","url":null,"abstract":"Hypercoagulation in the alveoli of the lungs is one of the causes of death in SARS-CoV2 virus infection. Hypercoagulation is defined by an elevation in D-Dimer, which typically rises on the fifth day of therapy. This parameter is not available in all hospitals and is still relatively expensive in preventing premature death. Platelets count and indices are suggested to describe the thromboinflammatory condition in COVID-19 patients. This research is an observational analytic study with a cross-sectional study design in 59 COVID-19 patients treated at Hassanuddin University Hospital. The patients who are declared COVID-19 based on the results of radiological examinations and PCR swabs underwent routine blood tests and D-Dimer before undergoing therapy. Data were analyzed using the Spearmen test in SPSS version 26 to reveal the correlation between platelet count, platelet indices, and D Dimer in COVID-19 patients with severe and non-severe conditions. Platelet count, platelet indices, especially MPV, and D-Dimer values were found to correlate in both groups COVID-19 using the Spearman rho correlation test (p 0.000) with strengths correlation between -44.6 and 60.5. There was a significant association between platelet count and MPV value with D-Dimer in COVID-19 patients.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82413300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-14DOI: 10.18196/mmjkk.v23i1.17031
Fathia Kesuma Dinanti, Sri Mulyani, Chodidjah Chodidjah
In type 2 diabetes mellitus, lipid profile is often found in the form of high-density lipoprotein (HDL) decrease. TNFa and IL-6 are proinflammatory cytokines that are elevated in the blood in many patients with diabetes mellitus. Turmeric is one of the natural ingredients that has anti-cholesterol and anti-inflammatory effects through the work of its active substance, curcumin. This study aimed to evaluate the effect of turmeric extract combined with metformin on HDL, TNFa, and IL-6 levels in diabetic rats. Twenty-four Wistar rats were injected intraperitoneally with streptozotocin and niacinamide. The diabetic rats then were divided into four groups; control group, metformin group, turmeric group, and combination group. The dose of metformin and turmeric which were given, respectively, 45mg/KgBW/day and 200 mg/KgBW/day. While the combo group was given half dose of each. Blood serum was taken to examine the HDL, IL-6, and TNFa levels. The levels of HDL, IL-6, TNFa on diabetic rats that received the combination of metformin and turmeric extract (p0.05) were the best among of all the groups. This means that the combination of metformin and turmeric is better in increasing HDL, reducing IL-6, and TNFa levels better than metformin or turmeric extract alone.
{"title":"Curcumin Improves Cytokines and HDL in Diabetic Wistar Rats","authors":"Fathia Kesuma Dinanti, Sri Mulyani, Chodidjah Chodidjah","doi":"10.18196/mmjkk.v23i1.17031","DOIUrl":"https://doi.org/10.18196/mmjkk.v23i1.17031","url":null,"abstract":"In type 2 diabetes mellitus, lipid profile is often found in the form of high-density lipoprotein (HDL) decrease. TNFa and IL-6 are proinflammatory cytokines that are elevated in the blood in many patients with diabetes mellitus. Turmeric is one of the natural ingredients that has anti-cholesterol and anti-inflammatory effects through the work of its active substance, curcumin. This study aimed to evaluate the effect of turmeric extract combined with metformin on HDL, TNFa, and IL-6 levels in diabetic rats. Twenty-four Wistar rats were injected intraperitoneally with streptozotocin and niacinamide. The diabetic rats then were divided into four groups; control group, metformin group, turmeric group, and combination group. The dose of metformin and turmeric which were given, respectively, 45mg/KgBW/day and 200 mg/KgBW/day. While the combo group was given half dose of each. Blood serum was taken to examine the HDL, IL-6, and TNFa levels. The levels of HDL, IL-6, TNFa on diabetic rats that received the combination of metformin and turmeric extract (p0.05) were the best among of all the groups. This means that the combination of metformin and turmeric is better in increasing HDL, reducing IL-6, and TNFa levels better than metformin or turmeric extract alone.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"408 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76830033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-27DOI: 10.18196/mmjkk.v23i1.17236
Ferry Fadzlul Rahman, S. Darsono, S. Sunarti
The competence of Posyandu (Integrated Service Post) cadres played a crucial role in response to the pandemic. They were responsible for raising awareness about COVID-19 and implementing preventive measures. The impact of their competence cannot be overstated and highlights the importance of investing in health worker training. This study aims to determine the factors related to the competence of Integrated Health Service Post cadres during the pandemic in the Samarinda Primary Healthcare working area. Observational research was employed with stratified random sampling, and primary data was collected from five Primary Healthcare in Samarinda. This study employed three steps to examine the effect of competency cadres: univariate analysis, bivariate analysis using the Spearman Rank test, and multivariate analysis with Multiple Linear Regression. The bivariate analysis results showed that supervision had a very strong correlation with the cadres’ competency, and social environment had a strong correlation with the cadres’ competency. At the same time, the organization had a moderate correlation with cadres’ competency. The multivariate test results showed that the social environment contributed 0.165 times to the competence of cadres, organizational support contributed 0.211 times in cadre competence, and supervision support contributed 0.652 times to cadre competence. It provides them with the necessary resources, training, and recognition for their work.
{"title":"The Factors Related to Cadres’ Competency in Integrated Health Service Post during Pandemic","authors":"Ferry Fadzlul Rahman, S. Darsono, S. Sunarti","doi":"10.18196/mmjkk.v23i1.17236","DOIUrl":"https://doi.org/10.18196/mmjkk.v23i1.17236","url":null,"abstract":"The competence of Posyandu (Integrated Service Post) cadres played a crucial role in response to the pandemic. They were responsible for raising awareness about COVID-19 and implementing preventive measures. The impact of their competence cannot be overstated and highlights the importance of investing in health worker training. This study aims to determine the factors related to the competence of Integrated Health Service Post cadres during the pandemic in the Samarinda Primary Healthcare working area. Observational research was employed with stratified random sampling, and primary data was collected from five Primary Healthcare in Samarinda. This study employed three steps to examine the effect of competency cadres: univariate analysis, bivariate analysis using the Spearman Rank test, and multivariate analysis with Multiple Linear Regression. The bivariate analysis results showed that supervision had a very strong correlation with the cadres’ competency, and social environment had a strong correlation with the cadres’ competency. At the same time, the organization had a moderate correlation with cadres’ competency. The multivariate test results showed that the social environment contributed 0.165 times to the competence of cadres, organizational support contributed 0.211 times in cadre competence, and supervision support contributed 0.652 times to cadre competence. It provides them with the necessary resources, training, and recognition for their work.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"15 12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83578780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-02DOI: 10.18196/mmjkk.v23i1.16623
Yusmawati Yusran, H. Lubis
Woodworkers are particularly susceptible to inhalation of sawdust exposure. Exposure to sawdust for a long time causes various health problems and causes the damage of the epithelium to a barrier. This study aims to identify whether inhaled sawdust can cause changes in the nasal mucosa and the occurrence of an inflammatory process. This study was a cross-sectional analytical study. Data were collected from July 2021 to January 2022 from the nasal cavity swab of 35 woodworkers who had worked for 1 to 5 years. The assessment was carried out by cytological examination to identify epithelial changes in the form of mild and moderate dysplasia, while the inflammation was found in the form of acute and chronic inflammation. Twenty-six (74.3%) samples were normal, 7 (20%) samples had mild dysplasia, and 2 (5.7%) samples had moderate dysplasia. Whereas 20 (57.1%) were found to have no inflammation, 8 (22.9%) were with acute inflammation, and 7 (20.0%) were found to have chronic inflammation). Fisher’s exact test showed a relationship between the inflammatory process and epithelial changes (p 0.020). In conclusion, sawdust inhaled showed changes in the epithelial mucosa and inflammatory processes of the nasal cavity.
{"title":"Epithelial Mucosal Changes and An Inflammation Process of the Cavum Nasi Due to Inhaled Sawdust","authors":"Yusmawati Yusran, H. Lubis","doi":"10.18196/mmjkk.v23i1.16623","DOIUrl":"https://doi.org/10.18196/mmjkk.v23i1.16623","url":null,"abstract":"Woodworkers are particularly susceptible to inhalation of sawdust exposure. Exposure to sawdust for a long time causes various health problems and causes the damage of the epithelium to a barrier. This study aims to identify whether inhaled sawdust can cause changes in the nasal mucosa and the occurrence of an inflammatory process. This study was a cross-sectional analytical study. Data were collected from July 2021 to January 2022 from the nasal cavity swab of 35 woodworkers who had worked for 1 to 5 years. The assessment was carried out by cytological examination to identify epithelial changes in the form of mild and moderate dysplasia, while the inflammation was found in the form of acute and chronic inflammation. Twenty-six (74.3%) samples were normal, 7 (20%) samples had mild dysplasia, and 2 (5.7%) samples had moderate dysplasia. Whereas 20 (57.1%) were found to have no inflammation, 8 (22.9%) were with acute inflammation, and 7 (20.0%) were found to have chronic inflammation). Fisher’s exact test showed a relationship between the inflammatory process and epithelial changes (p 0.020). In conclusion, sawdust inhaled showed changes in the epithelial mucosa and inflammatory processes of the nasal cavity.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72993056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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