S. Ulya, D. Ryangga, W. Wibowo, N. Nasution, S. Pawiro
Regarding the increasing use of small-field photons in clinical treatment, in this study, we investigate the use of small-field electron beams in clinical treatment. This study aimed to evaluate small-field electron beam dosimetry of the nasopharyngeal, thyroid, and ethmoid sinus carcinoma cases. Dose measurement was done using EBT3 film. In nasopharyngeal cases with a homogenous area and irregular surface, the dose discrepancies for 6 MeV energy were unpredictable except for the 5×5 cm2 field size. For all energies in 5×5 cm2 field size, the dose discrepancies were less than 3%. In these cases, we found that a smaller electron beam field will increase the percentage of the dose discrepancy. This is caused by the effect of the lateral scatter disequilibrium in a small field electron beam. For ethmoid sinus cases, dose discrepancy depends on the field size and inhomogeneity of bone and tissue organ. Based on the evaluation of doses on the spinal cord, chiasm, and larynx (OAR), it can be seen that these organs received a very small dose. From this result, a small field electron beam is recommended for cases with a homogeneous target. However, in cases with a heterogenous target, further investigation is needed.
{"title":"Current Approach of Small Field Electron Beam for Head and Neck Cases","authors":"S. Ulya, D. Ryangga, W. Wibowo, N. Nasution, S. Pawiro","doi":"10.33533/jpm.v17i1.5848","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5848","url":null,"abstract":"Regarding the increasing use of small-field photons in clinical treatment, in this study, we investigate the use of small-field electron beams in clinical treatment. This study aimed to evaluate small-field electron beam dosimetry of the nasopharyngeal, thyroid, and ethmoid sinus carcinoma cases. Dose measurement was done using EBT3 film. In nasopharyngeal cases with a homogenous area and irregular surface, the dose discrepancies for 6 MeV energy were unpredictable except for the 5×5 cm2 field size. For all energies in 5×5 cm2 field size, the dose discrepancies were less than 3%. In these cases, we found that a smaller electron beam field will increase the percentage of the dose discrepancy. This is caused by the effect of the lateral scatter disequilibrium in a small field electron beam. For ethmoid sinus cases, dose discrepancy depends on the field size and inhomogeneity of bone and tissue organ. Based on the evaluation of doses on the spinal cord, chiasm, and larynx (OAR), it can be seen that these organs received a very small dose. From this result, a small field electron beam is recommended for cases with a homogeneous target. However, in cases with a heterogenous target, further investigation is needed.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42488823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The main objective of this article is to explore the available classified information on Zingiber aromaticum Val. Rhizome and its active compound, Zerumbone. Throughout history, this plant has been utilized to treat various ailments such as abdominal disorders, cough, anemia, malaria, jaundice, arthritis, and infections. Recently, Zerumbone, a sesquiterpene compound found in the rhizomes, has gained attention for its biological activity. This article reviews the current research on the pharmacological activities of Z. aromaticum Val. Rhizome, with a specific focus on its active component, Zerumbone.This review found that the antioxidant and antiinflammatory effects of Zerumbone play a role in the pharmacological effects exhibited by Z. aromaticum, such as antidiabetic, antiparasitic, anti-hyperlipidemia, antianxiety, and antiaging effects. Additionally, the correlation between the biological activity of Zerumbone and the pharmacological activity of Z. aromaticum extract is discussed. This review provides a valuable reference for developing and further researching Zingiber aromaticum Val. and Zerumbone in medical treatments.
{"title":"Association of Zingiber Aromaticum Vaal. With Zerumbone and Its Biological Activity : A Literature Review","authors":"R. Murwanti, Rimadani Pratiwi, A. P. Gani","doi":"10.33533/jpm.v17i1.5816","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5816","url":null,"abstract":"The main objective of this article is to explore the available classified information on Zingiber aromaticum Val. Rhizome and its active compound, Zerumbone. Throughout history, this plant has been utilized to treat various ailments such as abdominal disorders, cough, anemia, malaria, jaundice, arthritis, and infections. Recently, Zerumbone, a sesquiterpene compound found in the rhizomes, has gained attention for its biological activity. This article reviews the current research on the pharmacological activities of Z. aromaticum Val. Rhizome, with a specific focus on its active component, Zerumbone.This review found that the antioxidant and antiinflammatory effects of Zerumbone play a role in the pharmacological effects exhibited by Z. aromaticum, such as antidiabetic, antiparasitic, anti-hyperlipidemia, antianxiety, and antiaging effects. Additionally, the correlation between the biological activity of Zerumbone and the pharmacological activity of Z. aromaticum extract is discussed. This review provides a valuable reference for developing and further researching Zingiber aromaticum Val. and Zerumbone in medical treatments.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44435286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Zaki, C. Adhiyanto, L. Hendarmin, Fauzia Ilman Naqiya, Dwi Karni, Zeti Harriyati
Small Mother Against Decapentaplegic 3 (SMAD3), an intracellular transducer protein in the TGF-β signaling pathway, has a role in maintaining joint cartilage. Many studies have been conducted to examine the effect of polymorphism in SMAD3 gene with the incidence of osteoarthritis (OA). The objective of this study is to identify the association of SMAD3 gene rs12901499 variation with the incidence of knee OA in Indonesian women. We conducted an analytic cross-sectional design involving 24 knee OA patients and 50 non-OA subjects. The DNA was taken from saliva and genotyped using a kit from Integrated DNA Technologies with the Real Time PCR method. In this study, we found that the GA genotype (heterozygous mutant) of the rs12901499 allele was the allele that most frequently (50%) appeared in knee OA patients as well as non-OA subjects (50%). The G allele frequency was higher than the A allele among all participants. The Chi-Square analysis showed that there was no statistically significant relationship between allele variations in the SMAD3 rs12901499 gene and knee OA (p=1). In conclusion, there was no statistically significant relationship between the rs12901499 genetic variation in the SMAD3 gene and the incidence of knee osteoarthritis in Indonesian aged women.
SmallMotherAgainstDecapetraptic3（SMAD3）是TGF-β信号通路中的一种细胞内转导蛋白，在维持关节软骨方面发挥作用。已经进行了许多研究来检验SMAD3基因多态性与骨关节炎（OA）发病率的影响。本研究的目的是确定SMAD3基因rs12901499变异与印尼妇女膝关节骨性关节炎发病率的关系。我们进行了一项横断面分析设计，涉及24名膝关节骨性关节炎患者和50名非骨性关节炎受试者。DNA取自唾液，并使用Integrated DNA Technologies的试剂盒和实时PCR方法进行基因分型。在本研究中，我们发现rs12901499等位基因的GA基因型（杂合突变体）是在膝关节OA患者和非OA受试者（50%）中最常见的等位基因（50%）。在所有参与者中，G等位基因频率高于A等位基因。卡方分析显示，SMAD3 rs12901499基因的等位基因变异与膝关节骨性关节炎之间没有统计学上显著的关系（p=1）。总之，SMAD3基因的rs12901499基因变异与印尼老年妇女膝骨关节炎的发病率之间没有统计学上的显著关系。
{"title":"Association of SMAD3 Gene rs12901499 Variation with Knee Osteoarthritis in Indonesian Aged Women","authors":"A. Zaki, C. Adhiyanto, L. Hendarmin, Fauzia Ilman Naqiya, Dwi Karni, Zeti Harriyati","doi":"10.33533/jpm.v17i1.5738","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5738","url":null,"abstract":"Small Mother Against Decapentaplegic 3 (SMAD3), an intracellular transducer protein in the TGF-β signaling pathway, has a role in maintaining joint cartilage. Many studies have been conducted to examine the effect of polymorphism in SMAD3 gene with the incidence of osteoarthritis (OA). The objective of this study is to identify the association of SMAD3 gene rs12901499 variation with the incidence of knee OA in Indonesian women. We conducted an analytic cross-sectional design involving 24 knee OA patients and 50 non-OA subjects. The DNA was taken from saliva and genotyped using a kit from Integrated DNA Technologies with the Real Time PCR method. In this study, we found that the GA genotype (heterozygous mutant) of the rs12901499 allele was the allele that most frequently (50%) appeared in knee OA patients as well as non-OA subjects (50%). The G allele frequency was higher than the A allele among all participants. The Chi-Square analysis showed that there was no statistically significant relationship between allele variations in the SMAD3 rs12901499 gene and knee OA (p=1). In conclusion, there was no statistically significant relationship between the rs12901499 genetic variation in the SMAD3 gene and the incidence of knee osteoarthritis in Indonesian aged women.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46320472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Toxoplasma gondii infection causes posterior uveitis and blindness. The diagnosis of ocular toxoplasmosis is based on typical clinical findings accompanied by positive anti-Toxoplasma serology. This study aims to see the clinical characteristics of ocular toxoplasmosis patients. Cross-sectional observational descriptive research is done. This study used 2019-2021 medical records from RSUP Dr. Mohammad Hoesin Palembang patients. The highest incidence of ocular toxoplasmosis at RSUP Dr. Mohammad Hoesin Palembang in 2019-2021 occurred in 2021 (54.5%). The most common age range found in this case is the age group of 0-19 years (45.5%) and the majority are women (72.7%). The majority of patients are out of work (45.5%) and live outside Palembang (81.8%). The most lateralization was found in the right eye (63.6%). The most commonly complained clinical symptom is blurred vision (90.9%). Clinical signs were found lesions of retinochoroiditis in the macular (45,5%), in the extramacular (18,2%), chorioretinal scar (90,9%), vitritis (54,5%), decreased visual acuity (100%), and increased IOP (36,4%). Anti-Toxoplasma IgG was found positive in all patients. The highest incidence of ocular toxoplasmosis was found in 2021. The most commonly complained clinical symptom is blurred vision and the most commonly found clinical sign is a decrease in visual acuity.
弓形虫感染可导致后葡萄膜炎和失明。眼弓形虫病的诊断是基于典型的临床表现，并伴有阳性的抗弓形虫血清学。本研究旨在了解眼弓形虫病患者的临床特点。进行了横断面观察描述性研究。这项研究使用了RSUP Mohammad Hoesin Palembang医生2019-2021年的病历。RSUP的眼弓形虫病发病率最高。Mohammad Hoesin Palembang在2019-2021年发生在2021年（54.5%）。该病例中最常见的年龄范围是0-19岁（45.5%），大多数是女性（72.7%）。大多数患者失业（45.5%临床表现为黄斑部视网膜脉络膜炎（45.5%）、黄斑外视网膜脉络膜炎症（18.2%）、脉络膜视网膜瘢痕（90.9%）、镜质炎（54.5%）、视力下降（100%）和眼压升高（36.4%）。抗弓形虫IgG在所有患者中均呈阳性。眼弓形虫病发病率最高的是2021年。最常见的临床症状是视力模糊，最常见的症状是视力下降。
{"title":"Clinical Characteristics of Ocular Toxoplasmosis Patients","authors":"Frashad Fanseca Alvarez, Petty Purwanita, Indri Seta Septadina","doi":"10.33533/jpm.v17i1.5653","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5653","url":null,"abstract":"Toxoplasma gondii infection causes posterior uveitis and blindness. The diagnosis of ocular toxoplasmosis is based on typical clinical findings accompanied by positive anti-Toxoplasma serology. This study aims to see the clinical characteristics of ocular toxoplasmosis patients. Cross-sectional observational descriptive research is done. This study used 2019-2021 medical records from RSUP Dr. Mohammad Hoesin Palembang patients. The highest incidence of ocular toxoplasmosis at RSUP Dr. Mohammad Hoesin Palembang in 2019-2021 occurred in 2021 (54.5%). The most common age range found in this case is the age group of 0-19 years (45.5%) and the majority are women (72.7%). The majority of patients are out of work (45.5%) and live outside Palembang (81.8%). The most lateralization was found in the right eye (63.6%). The most commonly complained clinical symptom is blurred vision (90.9%). Clinical signs were found lesions of retinochoroiditis in the macular (45,5%), in the extramacular (18,2%), chorioretinal scar (90,9%), vitritis (54,5%), decreased visual acuity (100%), and increased IOP (36,4%). Anti-Toxoplasma IgG was found positive in all patients. The highest incidence of ocular toxoplasmosis was found in 2021. The most commonly complained clinical symptom is blurred vision and the most commonly found clinical sign is a decrease in visual acuity. \u0000 ","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43703361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Suswati, Habibulloh Mustofa, Bagus Hermansyah, D. Agustina, E. N. Sakinah
Diabetic foot is a complication of diabetes mellitus that uses antibiotics to control the infection as the primary therapy. This study aimed to determine the type of bacteria and antimicrobial sensitivity patterns in diabetic foot. The samples were taken from the medical records of the patients with diabetic foot, who performed the swab culture and antimicrobial susceptibility testing in the inpatient and outpatient care in dr. Soebandi Regional Hospital. The samples used were the patients diagnosed with diabetic foot from January 1, 2014, to December 31, 2018. The data in this study were univariately analyzed. Forty-three pathogens were isolated from 40 patients with 12 ESBL isolates. The most common bacteria found were Gram-negative (90.7%), including Escherichia coli (33.33%), Klebsiella pneumoniae (12.82%) Pseudomonas aeruginosa (12.82%), Enterobacter cloacae (7.69%) and Proteus mirabilis (7.69%). Then, there were also 9.3% Gram-positive bacteria of all isolates, with Staphylococcus aureus as the most dominant species (50%). The antibiotic antimicrobial susceptibility testing also showed that Imipenem, amikacin, fosfomycin, cefoxitin, and netilmicin were the most sensitive antibiotics. The most common type of bacteria found was Escherichia coli, while the antibiotic still sensitive in most bacteria was imipenem.
{"title":"Antibiogram of Patients With Diabetic Foot at Dr. Soebandi Regional Hospital of Jember, Indonesia","authors":"E. Suswati, Habibulloh Mustofa, Bagus Hermansyah, D. Agustina, E. N. Sakinah","doi":"10.33533/jpm.v17i1.5753","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5753","url":null,"abstract":"Diabetic foot is a complication of diabetes mellitus that uses antibiotics to control the infection as the primary therapy. This study aimed to determine the type of bacteria and antimicrobial sensitivity patterns in diabetic foot. The samples were taken from the medical records of the patients with diabetic foot, who performed the swab culture and antimicrobial susceptibility testing in the inpatient and outpatient care in dr. Soebandi Regional Hospital. The samples used were the patients diagnosed with diabetic foot from January 1, 2014, to December 31, 2018. The data in this study were univariately analyzed. Forty-three pathogens were isolated from 40 patients with 12 ESBL isolates. The most common bacteria found were Gram-negative (90.7%), including Escherichia coli (33.33%), Klebsiella pneumoniae (12.82%) Pseudomonas aeruginosa (12.82%), Enterobacter cloacae (7.69%) and Proteus mirabilis (7.69%). Then, there were also 9.3% Gram-positive bacteria of all isolates, with Staphylococcus aureus as the most dominant species (50%). The antibiotic antimicrobial susceptibility testing also showed that Imipenem, amikacin, fosfomycin, cefoxitin, and netilmicin were the most sensitive antibiotics. The most common type of bacteria found was Escherichia coli, while the antibiotic still sensitive in most bacteria was imipenem.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42036423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There is an increase in the elderly population at this time, making the morbidity rate in the elderly also increase. In 2021, the number of elderly people who experienced illness in the past month was around 34.48%. Meanwhile, in 2022, the morbidity rate increased to 41.3%, The purpose of this study was to determine the determinants of the use of posyandu programs in empowering the elderly in Harjosari I Village, Medan Amplas District. The method used is a quantitative approach cross-sectional research design by surveying as many as 30 people as representatives of the population by accidental sampling by conducting interviews using online-based questionnaires, after the interview the data was analyzed statistically using univariate, bivariate and multivariate tests with a multi-stage model Analisys model to obtain crude values and adjusted oods ratio with an alpha significance of 5% (p<0.05). The results showed that the greatest influence on the utilization of the posyandu program was a distance of >100 meters with an exp value (B) of 2.56. The conclusion is that overall variables have a significant relationship with the utilization of elderly posyandu services with risks ranging from 1.43 to 2.56 times.
{"title":"Determinants of Integrated Services Post Programme Utilization in Elderly Empowerment in Medan Amplas District","authors":"Ivena Hotmarina Septiani Nainggolan, Fitriani Pramita Gurning","doi":"10.33533/jpm.v17i1.5843","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5843","url":null,"abstract":"There is an increase in the elderly population at this time, making the morbidity rate in the elderly also increase. In 2021, the number of elderly people who experienced illness in the past month was around 34.48%. Meanwhile, in 2022, the morbidity rate increased to 41.3%, The purpose of this study was to determine the determinants of the use of posyandu programs in empowering the elderly in Harjosari I Village, Medan Amplas District. The method used is a quantitative approach cross-sectional research design by surveying as many as 30 people as representatives of the population by accidental sampling by conducting interviews using online-based questionnaires, after the interview the data was analyzed statistically using univariate, bivariate and multivariate tests with a multi-stage model Analisys model to obtain crude values and adjusted oods ratio with an alpha significance of 5% (p<0.05). The results showed that the greatest influence on the utilization of the posyandu program was a distance of >100 meters with an exp value (B) of 2.56. The conclusion is that overall variables have a significant relationship with the utilization of elderly posyandu services with risks ranging from 1.43 to 2.56 times.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46960377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Theresa, Marlina Dewiastuti, Melly Kristanti, Cantika Vadia Aqli, Fakultas Kedokteran
Life expectancy is an indicator of successful health development. It is estimated the elderly population will increase along with the increase in life expectancy, in 2050 there will be an increase 3 times in the number of elderly from 2013. The increase in the number of elderly raises a health sector complicated problem. The elderly group will experience a decrease in health status either naturally or due to illness. Goals of the health program focus on life expectancy. West Java is the largest proportion with Indramayu a city in West Java that has a target life expectancy that reaches the target. The government's efforts to improve the elderly welfare are realized in various programs so that an increase in the elderly population does not increase health problems. Indicators of elderly health can be measured by active aging (AA).. The determinants of the AA component, which include health and well-being, are indicators for assessing healthy life expectancy in the elderly. Assessment of healthy life expectancy is assessed from several determinants. Assessment of healthy life expectancy can determine health development targets, especially in the elderly. This study associated dietary patterns and smoking habits with increased healthy life expectancy.
{"title":"Determinants of Active Aging Affect Healthy Life Expectation","authors":"R. Theresa, Marlina Dewiastuti, Melly Kristanti, Cantika Vadia Aqli, Fakultas Kedokteran","doi":"10.33533/jpm.v17i1.5837","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5837","url":null,"abstract":"Life expectancy is an indicator of successful health development. It is estimated the elderly population will increase along with the increase in life expectancy, in 2050 there will be an increase 3 times in the number of elderly from 2013. The increase in the number of elderly raises a health sector complicated problem. The elderly group will experience a decrease in health status either naturally or due to illness. Goals of the health program focus on life expectancy. West Java is the largest proportion with Indramayu a city in West Java that has a target life expectancy that reaches the target. The government's efforts to improve the elderly welfare are realized in various programs so that an increase in the elderly population does not increase health problems. Indicators of elderly health can be measured by active aging (AA).. The determinants of the AA component, which include health and well-being, are indicators for assessing healthy life expectancy in the elderly. Assessment of healthy life expectancy is assessed from several determinants. Assessment of healthy life expectancy can determine health development targets, especially in the elderly. This study associated dietary patterns and smoking habits with increased healthy life expectancy.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49637929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Pasaribu, Zulfahri Lubis, Muhammad Kevin Humala Sakti Siregar, A. Fitria, Amar Ma’ruf
Therapeutic communication helps patients solve problems, reduce emotional and mental burdens, and take effective action, while self-esteem is an individual's evaluation of their ability, meaningfulness, success, and worth. This study examines how therapeutic communication affects elderly self-esteem in Laut Dendang Village in Percut Sei Tuan District. This study uses pre-test-post-test quasi-experimental design. This study has 62 participants. Purposive sampling yielded 17 respondents. The Paired T-test demonstrated that therapeutic dialogue affects senior self-esteem in Laut Dendang Village in Percut Sei Tuan District. The data analysis shows a mean value of and a p-value of 0.000. (2.100). Therapeutic dialogue raised self-esteem 2.1%. Therapeutic dialogue improves self-esteem in elderly Laut Dendang Village residents in Percut Sei Tuan District. This message substantially impacts weak and powerless self-confidence.
治疗性沟通有助于患者解决问题，减轻情绪和精神负担，并采取有效行动，而自尊是个人对自己能力、意义、成功和价值的评估。本研究调查了治疗性沟通如何影响打击乐Sei Tuan区Laut Dendang村的老年人自尊。本研究采用测试前-测试后准实验设计。这项研究有62名参与者。有目的的抽样产生了17名受访者。配对T检验表明，治疗性对话会影响Perct Sei Tuan区Laut Dendang村的老年人自尊。数据分析显示平均值为，p值为0.000。（2.100）.治疗性对话提高了2.1%的自尊。治疗性对话改善了Perct Sei Tuan区Laut Dendang村老年居民的自尊。这一信息对软弱无能的自信心产生了重大影响。
{"title":"The Effect of Therapeutic Communication on the Level of Self-Esteem in the Elderly: A Case Study of the Laut Dendang Village in the Percut Sei Tuan District","authors":"M. Pasaribu, Zulfahri Lubis, Muhammad Kevin Humala Sakti Siregar, A. Fitria, Amar Ma’ruf","doi":"10.33533/jpm.v17i1.5501","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5501","url":null,"abstract":"Therapeutic communication helps patients solve problems, reduce emotional and mental burdens, and take effective action, while self-esteem is an individual's evaluation of their ability, meaningfulness, success, and worth. This study examines how therapeutic communication affects elderly self-esteem in Laut Dendang Village in Percut Sei Tuan District. This study uses pre-test-post-test quasi-experimental design. This study has 62 participants. Purposive sampling yielded 17 respondents. The Paired T-test demonstrated that therapeutic dialogue affects senior self-esteem in Laut Dendang Village in Percut Sei Tuan District. The data analysis shows a mean value of and a p-value of 0.000. (2.100). Therapeutic dialogue raised self-esteem 2.1%. Therapeutic dialogue improves self-esteem in elderly Laut Dendang Village residents in Percut Sei Tuan District. This message substantially impacts weak and powerless self-confidence.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47301921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Sidipratomo, J. Pandelaki, Samuel Widjaja, Jason Jason
Blunt thoracic trauma is one of the main contributors to trauma-related deaths, with the broad possibility of pathological chest injury. Imaging plays an important role in detecting most of internal organ injuries. Here we presented a 56-years-old male with progressive chest pain following blunt chest trauma several days prior without any early intervention. Chest radiograph showed rib fractures, pneumothorax, atelectasis, and raised left hemidiaphragm. Further CT scan evaluation identified additional hemothorax, subcutaneous emphysema and confirming the fourth to tenth rib fractures, pneumothorax, and unilateral hemidiaphragm elevation. As seen in our case, chest radiograph is crucial in initial evaluation of chest injury, usually through identification of pathological landmark. While chest radiograph is limited to one projection, CT scan provide a global evaluation of a region with a high sensitivity and specificity in detecting and confirming most of the injuries. Thus, one must not overlook any lightly appeared blunt thoracic trauma while optimizing the use of radiography and CT scan for the evaluation of injuries.
{"title":"Multiple Radiologic Findings in a Simple Blunt Thoracic Trauma","authors":"P. Sidipratomo, J. Pandelaki, Samuel Widjaja, Jason Jason","doi":"10.33533/jpm.v17i1.5123","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5123","url":null,"abstract":"Blunt thoracic trauma is one of the main contributors to trauma-related deaths, with the broad possibility of pathological chest injury. Imaging plays an important role in detecting most of internal organ injuries. Here we presented a 56-years-old male with progressive chest pain following blunt chest trauma several days prior without any early intervention. Chest radiograph showed rib fractures, pneumothorax, atelectasis, and raised left hemidiaphragm. Further CT scan evaluation identified additional hemothorax, subcutaneous emphysema and confirming the fourth to tenth rib fractures, pneumothorax, and unilateral hemidiaphragm elevation. As seen in our case, chest radiograph is crucial in initial evaluation of chest injury, usually through identification of pathological landmark. While chest radiograph is limited to one projection, CT scan provide a global evaluation of a region with a high sensitivity and specificity in detecting and confirming most of the injuries. Thus, one must not overlook any lightly appeared blunt thoracic trauma while optimizing the use of radiography and CT scan for the evaluation of injuries.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43051250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Polimorfisme gen C957T merupakan synonymous mutation yang terletak pada pasang basa ke-957 gen DRD2. Terdapat perbedaan konformasi antara mRNA 957T dengan mRNA 957C, yaitu mRNA 957T kurang stabil dan lebih rentan terhadap degradasi. Tujuan penelitian ini untuk menunjukkan gambaran dosis terapi aripiprazole pasien skizofrenia dengan polimorfisme gen DRD2 pada titik rs6277 (C957T). Penelitian ini merupakan penelitian deskriptif dengan menggunakan desain penelitian cross sectional. Analisis data dengan menggunakan analisis univariat untuk mengidentifikasi responden berupa usia, jenis kelamin, polimorfisme gen DRD2, dan dosis terapi aripiprazole. Pengambilan data dilakukan dengan menggunakan data kuesioner untuk mendapatkan data karakteristik responden serta pengambilan sampel darah untuk mendapat data polimorfismen gen DRD2. Responden penelitian ini terdapat 60 orang responden yang memenuhi kriteria. Hasil penelitian ini didapatkan bahwa sebagian besar responden memiliki karakteristik usia 21-39 tahun (65,0%), jenis kelamin laki-laki (71,7%), dosis terapi aripiprazole 10 mg (60,0%), dan alel C (65,0 %) pada polimorfisme gen DRD2 pada titik rs6277 (C957T). Aripiprazole diduga menyebabkan multiplisitas fungsional pada reseptor dopamin D2 jalur pascasinaps, dimana pengikatan preferensial untuk konformasi berbeda dari reseptor D2, untuk mengaktifkan jalur transduksi diferensial sesuai dengan subtipe neuron dimana mereka diekspresikan. Berdasarkan penelitian yang dilakukan maka perlu dilakukan studi lebih lanjut untuk penentuan kadar konsentrasi aripiprazole di dalam darah pasien skizofrenia dan dengan mempertimbangkan lama terapi dengan evaluasi lebih lama
{"title":"GAMBARAN DOSIS TERAPI ARIPIPRAZOLE PASIEN SKIZOFRENIA DENGAN POLIMORFISME GEN DRD2 PADA TITIK RS6277 (C957T)","authors":"","doi":"10.32502/sm.v13i2.3825","DOIUrl":"https://doi.org/10.32502/sm.v13i2.3825","url":null,"abstract":"Polimorfisme gen C957T merupakan synonymous mutation yang terletak pada pasang basa ke-957 gen DRD2. Terdapat perbedaan konformasi antara mRNA 957T dengan mRNA 957C, yaitu mRNA 957T kurang stabil dan lebih rentan terhadap degradasi. Tujuan penelitian ini untuk menunjukkan gambaran dosis terapi aripiprazole pasien skizofrenia dengan polimorfisme gen DRD2 pada titik rs6277 (C957T). Penelitian ini merupakan penelitian deskriptif dengan menggunakan desain penelitian cross sectional. Analisis data dengan menggunakan analisis univariat untuk mengidentifikasi responden berupa usia, jenis kelamin, polimorfisme gen DRD2, dan dosis terapi aripiprazole. Pengambilan data dilakukan dengan menggunakan data kuesioner untuk mendapatkan data karakteristik responden serta pengambilan sampel darah untuk mendapat data polimorfismen gen DRD2. Responden penelitian ini terdapat 60 orang responden yang memenuhi kriteria. Hasil penelitian ini didapatkan bahwa sebagian besar responden memiliki karakteristik usia 21-39 tahun (65,0%), jenis kelamin laki-laki (71,7%), dosis terapi aripiprazole 10 mg (60,0%), dan alel C (65,0 %) pada polimorfisme gen DRD2 pada titik rs6277 (C957T). Aripiprazole diduga menyebabkan multiplisitas fungsional pada reseptor dopamin D2 jalur pascasinaps, dimana pengikatan preferensial untuk konformasi berbeda dari reseptor D2, untuk mengaktifkan jalur transduksi diferensial sesuai dengan subtipe neuron dimana mereka diekspresikan. Berdasarkan penelitian yang dilakukan maka perlu dilakukan studi lebih lanjut untuk penentuan kadar konsentrasi aripiprazole di dalam darah pasien skizofrenia dan dengan mempertimbangkan lama terapi dengan evaluasi lebih lama","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82709469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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