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The Indications for Catheter Ablation of Atrial Fibrillation 心房颤动导管消融的适应症
Q4 Medicine Pub Date : 2022-12-26 DOI: 10.30702/ujcvs/22.30(04)/sa048-111114
O. S. Stychynskyi, P. O. Almiz
Since the introduction of catheter ablation of atrial fibrillation (AF), it developed from a specialized experimental procedure into a common treatment option to prevent recurrent AF. In recent years substantial improvement has been made in the equipment and techniques used in catheter ablation of AF. The volume of procedures expanded year after year. Naturally, this has been reflected on indications for catheter ablation. The aim. To study the changes in indications for catheter ablations of AF which has occurred during the last decade, according to European and American literature. Materials and methods. We reviewed four documents related to the management of AF: 2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation ofatrial fibrillation; 2017 HRS/EHRA/ECAS/APHRS/SOLEACE expert consensus statement on catheter and surgical ablation of atrial fibrillation; 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS; 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). Results. During the analyzed period there have been a lot of changes inindications for catheter ablation of AF. Recent years guidelines pointed out that a decision on AF catheter ablation should be based on the patient’s preferences. It is recommended to take into consideration the procedural risks andmajor risk factors of arrhythmia recurrence. All this should be discussed with patient. Today antiarrhythmic drugs still remain a first-line rhythm control therapy. Catheter ablation is recommended after drug therapy failure in patients with all clinical forms of AF. In AF patients with heart failure, when tachycardia-induced cardiomyopathy is highly probable, catheter ablation is recommended as a first-line therapy. Conclusion. Catheter ablation is effective in maintaining sinus rhythm in patients with paroxysmal and persistent AF. Its role as a method of rhythm control has increased during thelast decade.
自心房颤动(AF)的导管消融引入以来,它从一种专门的实验手术发展成为预防房颤复发的常用治疗选择。近年来,房颤导管消融的设备和技术有了实质性的改进,手术数量逐年增加。当然,这也反映在导管消融的适应症上。的目标。根据欧美文献,研究近十年来房颤导管消融适应症的变化。材料和方法。我们回顾了四份与房颤管理相关的文件:2012年HRS/EHRA/ECAS专家共识声明:房颤导管和手术消融;2017年HRS/EHRA/ECAS/APHRS/SOLEACE房颤导管和手术消融专家共识声明;与EACTS合作制定的2016 ESC房颤管理指南;2020年ESC房颤诊断和治疗指南与欧洲心胸外科协会(EACTS)合作制定。结果。在分析期间,房颤导管消融的适应症发生了很多变化。近年来的指南指出,房颤导管消融的决定应根据患者的喜好。建议考虑手术风险和心律失常复发的主要危险因素。所有这些都应该和病人讨论。今天,抗心律失常药物仍然是控制心律的一线疗法。对于所有临床形式的房颤患者,在药物治疗失败后,推荐导管消融。对于房颤合并心衰患者,当极有可能发生心动过速引起的心肌病时,推荐导管消融作为一线治疗。结论。导管消融在维持阵发性和持续性房颤患者的窦性心律方面是有效的。在过去十年中,它作为一种心律控制方法的作用越来越大。
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引用次数: 0
Intracoronary Administration of Drugs in Clinical Practice 临床应用中的冠状动脉内给药
Q4 Medicine Pub Date : 2022-12-26 DOI: 10.30702/ujcvs/22.30(04)/ss051-1219
S. V. Salo, Valentyn O. Shumakov, A. Y. Gavrylyshyn, O. Levchyshyna, S. S. Shpak
Intracoronary administration of drugs allows to achieve the fastest possible effect in interventional cardiology. This allows to avoid all the biological filters of the body and achieve the required concentration of the active substance at the injection site. Also, given the local action, systemic side effects are nearly absent. The aim. To study the literature data of the leading countries of the world in the field of intracoronary drug administration. To analyze the experience of different centers on the use of various medications in the treatment of the phenomenon of distal microembolization. Results. One of the first drugs administered intracoronary was streptokinase for the treatment of acute myocardial infarction. After that, it became clear that this method of delivering drugs is possible and can be used. With the beginning of the treatment of acute coronary syndromes by stenting, one of the possible complications arose in the form of no-reflow. At the same time, realizing that this is a local problem, they began to use the possibility of intracoronary administration of drugs to treat this phenomenon. The main advantage of this method is quick response to drug administration. Today, the drugs of choice in the treatment of no-reflow are verapamil, adenosine, nitroprusside, adrenaline. On the other hand, probably the most common drug that is administered intracoronary is nitroglycerin. It is used as a vasodilator in the event of spasm of the coronary arteries. Subsequently, it has been recommended to deliver drugs via a microcatheter or aspiration catheter to achieve even more selective effect in the area of the affected vessel, and this also minimizes drug loss due to coronary reflux into the aortic sinuses while usinga guiding catheter. Work is also underway on the use of intracoronary insulin in acute coronary syndrome in order to reduce the area of damage in myocardial infarction. It is also very promising to study the introduction of stem cells directlyinto the myocardium through a microcatheter in order to regenerate the myocardium after a heart attack. Conclusions. Intracoronary administration of drugs allows to achieve the maximum effect in the shortest possible time. Today, many drugs can be used in this way, starting from the treatment of the phenomenon of distal microembolization and ending with myocardial regeneration after myocardial infarction.
冠状动脉内给药可以在介入心脏病学中实现最快的效果。这允许避开身体的所有生物过滤器,并在注射部位达到所需的活性物质浓度。此外,考虑到局部作用,系统性副作用几乎不存在。目标。研究世界领先国家在冠状动脉内药物管理领域的文献资料。分析不同中心使用各种药物治疗远端微栓塞现象的经验。后果最早在冠状动脉内给药的药物之一是链激酶,用于治疗急性心肌梗死。在那之后,很明显,这种递送药物的方法是可能的,并且可以使用。随着支架治疗急性冠状动脉综合征的开始,一种可能的并发症以无复流的形式出现。同时,意识到这是一个局部问题,他们开始利用冠状动脉内给药的可能性来治疗这种现象。这种方法的主要优点是对药物给药反应迅速。如今,治疗无复流的首选药物是维拉帕米、腺苷、硝普钠和肾上腺素。另一方面,冠状动脉内给药最常见的药物可能是硝酸甘油。在冠状动脉痉挛的情况下,它被用作血管舒张剂。随后,建议通过微导管或抽吸导管输送药物,以在受影响血管区域实现更具选择性的效果,这也最大限度地减少了在使用引导导管时因冠状动脉回流进入主动脉窦而造成的药物损失。在急性冠状动脉综合征中使用冠状动脉内胰岛素以减少心肌梗死的损伤面积的工作也在进行中。研究通过微导管将干细胞直接引入心肌以在心脏病发作后再生心肌也是非常有希望的。结论。冠状动脉内给药可以在尽可能短的时间内达到最大效果。如今,许多药物都可以这样使用,从治疗远端微栓塞现象开始,到心肌梗死后的心肌再生结束。
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引用次数: 0
The Occurrence of Thrombotic Complications Due to Combat Trauma Against the Background of the COVID-19 Pandemic COVID-19大流行背景下战斗创伤致血栓性并发症的发生
Q4 Medicine Pub Date : 2022-12-26 DOI: 10.30702/ujcvs/22.30(04)/gr058-115121
O. Gogayeva, Mykola L. Rudenko, O. Nudchenko
An important point in the provision of highly specialized cardiac surgical care for combat trauma is determination of the optimal time, method and volume of surgical intervention, taking into account the persisting threat of infection with the SARS-COV-2 virus and associated thrombotic complications. The aim. To investigate the mechanism of development and methods of prevention of thrombotic complications resulting from combat trauma against the background of the COVID-19 pandemic. Materials and methods. We analyzed clinical case of patient R., a 37-year-old soldier with a postinfarction thrombosed aneurysm of the left ventricle. The patient underwent standard clinical and laboratory tests, electrocardiography, echocardiography, coronary angiography, computed tomography of the chest, duplex scanning of carotid arteries, arteries and veins of the upper and lower extremities. It was established that 4 months ago, during a combat mission, the service-man received a mine-explosive injury, shrapnel wounds of lower extremities, multifragmentary fracture of the right ϐibula and a gunshot wound to the right chest. The causes of post-traumatic myocardial infarction are mine-explosive injury, intramural course of the left anterior descending artery, youngage, poorly developed collaterals of coronary arteries, long-term transportation during the stages of medical evacuation and post-traumatic stress disorder. A month ago, the patient was diagnosed with COVID-19, thromboembolism of the right main branch of the pulmonary artery, for which thrombolytic therapy was performed. Follow-up computed tomography showed the signs of thromboembolism of the pulmonary arteries. Ultrasound examination revealed thromboses of upper and lower limbs. Thrombotic complications against the background of combat polytrauma are the result of hypercoagulation, acute inϐlammation with the release of proinϐlammatory cytokines and damage of the endothelium. SARS-COV-2 infection triggers a state of hypercoagulation and creates additional conditions for the occurrence of arterial and venous thrombosis. Considering the nature of the thrombotic lesions, was made a decision to postpone the cardiosurgical intervention for 3 months. Conclusions. Thrombotic complications are an urgent problem after combat trauma. COVID-19 is an additional risk factor for hypercoagulation and a reason for delaying elective cardiac surgery. Conducting an electrocardiography to the wounded, regardless of age, is crucial for timely diagnosis andtreatment of acute coronary events. It is important to initiate anticoagulant therapy after eliminating all possible sources of bleeding due to the high risk of thrombotic complications against the background of chest trauma and limb fractures.
考虑到严重急性呼吸系统综合征冠状病毒2型感染的持续威胁和相关的血栓性并发症,为对抗创伤提供高度专业化的心脏外科护理的一个重要点是确定最佳手术干预时间、方法和量。目标。探讨在新冠肺炎大流行的背景下,因战斗创伤导致的血栓性并发症的发展机制和预防方法。材料和方法。我们分析了患者R的临床病例,他是一名37岁的士兵,患有梗死后血栓形成的左心室动脉瘤。患者接受了标准的临床和实验室测试、心电图、超声心动图、冠状动脉造影、胸部计算机断层扫描、颈动脉、上下肢动脉和静脉的双重扫描。据证实,4个月前,在一次作战任务中,这名服役人员受了地雷爆炸伤、下肢弹片伤、右下颌多发性骨折和右胸部枪伤。创伤后心肌梗死的原因是地雷爆炸伤、左前降支壁内走行、年轻、冠状动脉侧支发育不良、医疗后送阶段的长期运输和创伤后应激障碍。一个月前,患者被诊断为新冠肺炎,肺动脉右主干血栓栓塞症,并进行了溶栓治疗。随后的计算机断层扫描显示了肺动脉血栓栓塞的迹象。超声检查显示上肢和下肢有血栓形成。在多发性创伤的背景下,血栓并发症是高凝状态的结果,急性炎症伴随促炎细胞因子的释放和内皮损伤。严重急性呼吸系统综合征冠状病毒2型感染会引发高凝状态,并为动脉和静脉血栓形成的发生创造额外条件。考虑到血栓性病变的性质,我们决定将心脏手术干预推迟3个月。结论。血栓并发症是战斗创伤后的一个紧迫问题。新冠肺炎是高凝状态的一个额外风险因素,也是推迟择期心脏手术的原因。无论年龄大小,对伤员进行心电图检查对于及时诊断和治疗急性冠状动脉事件至关重要。重要的是,在消除所有可能的出血源后开始抗凝治疗,因为在胸部创伤和四肢骨折的背景下,血栓并发症的风险很高。
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引用次数: 1
Diagnosis of Postinfarction Pseudoaneurysm of the Left Ventricular Free Wall after Coronary Stenting: Case Report 冠状动脉支架置入术后梗死后左室游离壁假性动脉瘤的诊断(附1例报告)
Q4 Medicine Pub Date : 2022-12-26 DOI: 10.30702/ujcvs/22.30(04)/ld054-133139
Y. Lebedieva, S. Y. Denysov, Mykyta M. Brianskyi, Marchelina S. Gergi, Ramil A. Aliyev
The article is dedicated to topical issues of diagnosis and surgical treatment of postinfarction left ventricular (LV) myocardial rupture. Postinfarction LV rupture is one of the most life-threatening complications of acute myocardial infarction (AMI). Given the low prevalence, this complication almost always leads to a fatal outcome. At the same time, a large proportion of patients (over 60%) die before the diagnosis is verified, suddenly, without specific clinical precursors. The aim. To draw the attention of doctors to the problem of diagnosis and surgical treatment of LV myocardial rupture as a complication of AMI. The article describes a clinical case of diagnosis of pseudoaneurysm of the LV free wall after coronary stenting. The peculiarity of this case was absence of a typical pain syndrome, electrocardiographic and echocardiographic signs, suggesting the presenceof such a mechanical complication of AMI. Special attention is paid to the analysis of factors enabling to assess the risk of developing this complication in patients with AMI. The given clinical case demonstrates the importance of early hospitalization and myocardial revascularization by stenting in order to prevent mechanical complications of AMI. Timely diagnosis and urgent surgical treatment of LV myocardial ruptures can reduce mortality due to mechanical complications of AMI. Conclusions. Timely hospitalization and revascularization of the myocardium in AMI patients reduce the risk of LV rupture in the affected area. The use of echocardiography makesit possible to detect severe complications of AMI with sufficient sensitivity. The only effective treatment method forLV rupture is urgent surgical intervention. Postinfarction myocardial rupture repair is a difficult task considering the initial severity of the patient’s clinical condition, the significant volume and technical complexity of the surgical intervention.
本文致力于探讨梗死后左心室(LV)心肌破裂的诊断和外科治疗的热点问题。梗死后左心室破裂是急性心肌梗死(AMI)最危及生命的并发症之一。鉴于发病率低,这种并发症几乎总是会导致致命的后果。与此同时,很大一部分患者(超过60%)在确诊之前突然死亡,没有具体的临床前兆。目标。提请医生注意急性心肌梗死并发左心室心肌破裂的诊断和手术治疗问题。本文介绍一例冠状动脉支架置入术后诊断左心室游离壁假性动脉瘤的临床病例。该病例的特点是没有典型的疼痛综合征、心电图和超声心动图体征,表明存在AMI的机械并发症。特别注意分析能够评估AMI患者发生这种并发症的风险的因素。给定的临床病例证明了早期住院和支架植入心肌血运重建对预防AMI机械并发症的重要性。及时诊断和紧急手术治疗左心室心肌破裂可以降低AMI机械并发症的死亡率。结论。AMI患者及时住院和心肌血运重建可降低患区左心室破裂的风险。超声心动图的使用使其能够以足够的灵敏度检测AMI的严重并发症。左心室破裂的唯一有效治疗方法是紧急手术干预。考虑到患者临床状况的最初严重性、手术干预的巨大规模和技术复杂性,梗死后心肌破裂修复是一项艰巨的任务。
{"title":"Diagnosis of Postinfarction Pseudoaneurysm of the Left Ventricular Free Wall after Coronary Stenting: Case Report","authors":"Y. Lebedieva, S. Y. Denysov, Mykyta M. Brianskyi, Marchelina S. Gergi, Ramil A. Aliyev","doi":"10.30702/ujcvs/22.30(04)/ld054-133139","DOIUrl":"https://doi.org/10.30702/ujcvs/22.30(04)/ld054-133139","url":null,"abstract":"The article is dedicated to topical issues of diagnosis and surgical treatment of postinfarction left ventricular (LV) myocardial rupture. Postinfarction LV rupture is one of the most life-threatening complications of acute myocardial infarction (AMI). Given the low prevalence, this complication almost always leads to a fatal outcome. At the same time, a large proportion of patients (over 60%) die before the diagnosis is verified, suddenly, without specific clinical precursors. \u0000The aim. To draw the attention of doctors to the problem of diagnosis and surgical treatment of LV myocardial rupture as a complication of AMI. \u0000The article describes a clinical case of diagnosis of pseudoaneurysm of the LV free wall after coronary stenting. The peculiarity of this case was absence of a typical pain syndrome, electrocardiographic and echocardiographic signs, suggesting the presenceof such a mechanical complication of AMI. Special attention is paid to the analysis of factors enabling to assess the risk of developing this complication in patients with AMI. The given clinical case demonstrates the importance of early hospitalization and myocardial revascularization by stenting in order to prevent mechanical complications of AMI. Timely diagnosis and urgent surgical treatment of LV myocardial ruptures can reduce mortality due to mechanical complications of AMI. \u0000Conclusions. Timely hospitalization and revascularization of the myocardium in AMI patients reduce the risk of LV rupture in the affected area. The use of echocardiography makesit possible to detect severe complications of AMI with sufficient sensitivity. The only effective treatment method forLV rupture is urgent surgical intervention. Postinfarction myocardial rupture repair is a difficult task considering the initial severity of the patient’s clinical condition, the significant volume and technical complexity of the surgical intervention.","PeriodicalId":33680,"journal":{"name":"Ukrayins''kii zhurnal sertsevosudinnoyi khirurgiyi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44297238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Restenosis Rate and Reinterventions after Aortic Arch Repair in Infants 婴儿主动脉弓修复术后再狭窄率和再狭窄情况
Q4 Medicine Pub Date : 2022-12-26 DOI: 10.30702/ujcvs/22.30(04)/tg056-5965
I. Truba, Oleksandr S. Golovenko, I. Dziuryi
The aim. This study aims to determine the reintervention rate in infantsundergoing aortic arch repair and to analyze risk factors and evaluate the results of reinterventions. Materials and methods. This retrospective study examines 445 infants with aortic arch hypoplasia who under-went aortic arch reconstruction between 2011 and 2019. The study included only patients with two-ventricle physiology and subsequent two-ventricle repair. Techniques for primary repair included extended end-to-end anastomosis (n = 348), end-to-side anastomosis (n = 611), autologous pericardial patch repair (n = 16). Results. The overall mortality in the entire study group was 3.3 %. Follow-up period ranged from 1 month to 9.4 years (mean 2.8 ± 2.5 years). Restenosis at the site of aortic arch repair was identiϐied in 47 (10.5 %) patients. Of these, 12 patients underwent surgical reconstruction of the aortic arch, 27 patients underwent balloon angioplasty, and in 8 patients both methods were used. Freedom from reintervention was 89.4 % at 1-year follow-up and 87.5 % at 4-year follow-up. The most determining factorsfor restenosis were related to hypoplastic proximal aortic arch and body weight less than 2.5 kg. Conclusions. Surgical treatment of aortic arch hypoplasia in newborns and infants is effective and shows good immediate and long-term results. Anatomical correction of reobstruction at the level of the aortic arch is safe with both endovacular and surgical methods with low mortality and incidence of repeated interventions. Identified risk factors for mortality and recurrent aortic arch interventions help to improve the treatment of aortic arch hypoplasia in patients under 1 year of age.
目标。本研究旨在确定婴儿主动脉弓修复的再干预率,分析风险因素并评估再干预的结果。材料和方法。这项回顾性研究检查了445名主动脉弓发育不全的婴儿,他们在2011年至2019年间进行了主动脉弓重建。该研究仅包括具有双心室生理学和随后的双心室修复的患者。主要修复技术包括延长端对端吻合(n=348)、端对侧吻合(n=611)、自体心包补片修复(n=16)。后果整个研究组的总死亡率为3.3%。随访时间为1个月至9.4年(平均2.8±2.5年)。47例(10.5%)患者在主动脉弓修复部位发现再狭窄。其中,12名患者接受了主动脉弓的外科重建,27名患者进行了球囊血管成形术,8名患者同时使用了这两种方法。1年随访时无再干预率为89.4%,4年随访时为87.5%。再狭窄的主要决定因素与近端主动脉弓发育不全和体重小于2.5kg有关。新生儿和婴儿主动脉弓发育不全的外科治疗是有效的,并显示出良好的近期和长期效果。在主动脉弓水平上对再阻塞进行解剖矫正是安全的,无论是采用真空内还是手术方法,死亡率和重复干预的发生率都很低。已确定的死亡率风险因素和复发性主动脉弓干预措施有助于改善1岁以下患者主动脉弓发育不全的治疗。
{"title":"Restenosis Rate and Reinterventions after Aortic Arch Repair in Infants","authors":"I. Truba, Oleksandr S. Golovenko, I. Dziuryi","doi":"10.30702/ujcvs/22.30(04)/tg056-5965","DOIUrl":"https://doi.org/10.30702/ujcvs/22.30(04)/tg056-5965","url":null,"abstract":"The aim. This study aims to determine the reintervention rate in infantsundergoing aortic arch repair and to analyze risk factors and evaluate the results of reinterventions. \u0000Materials and methods. This retrospective study examines 445 infants with aortic arch hypoplasia who under-went aortic arch reconstruction between 2011 and 2019. The study included only patients with two-ventricle physiology and subsequent two-ventricle repair. Techniques for primary repair included extended end-to-end anastomosis (n = 348), end-to-side anastomosis (n = 611), autologous pericardial patch repair (n = 16). \u0000Results. The overall mortality in the entire study group was 3.3 %. Follow-up period ranged from 1 month to 9.4 years (mean 2.8 ± 2.5 years). Restenosis at the site of aortic arch repair was identiϐied in 47 (10.5 %) patients. Of these, 12 patients underwent surgical reconstruction of the aortic arch, 27 patients underwent balloon angioplasty, and in 8 patients both methods were used. Freedom from reintervention was 89.4 % at 1-year follow-up and 87.5 % at 4-year follow-up. The most determining factorsfor restenosis were related to hypoplastic proximal aortic arch and body weight less than 2.5 kg. \u0000Conclusions. Surgical treatment of aortic arch hypoplasia in newborns and infants is effective and shows good immediate and long-term results. Anatomical correction of reobstruction at the level of the aortic arch is safe with both endovacular and surgical methods with low mortality and incidence of repeated interventions. Identified risk factors for mortality and recurrent aortic arch interventions help to improve the treatment of aortic arch hypoplasia in patients under 1 year of age.","PeriodicalId":33680,"journal":{"name":"Ukrayins''kii zhurnal sertsevosudinnoyi khirurgiyi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49299265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extracranial Carotid Artery Aneurysms: 20-Year Experience of Surgical Management 颅外颈动脉动脉瘤:20年的外科治疗经验
Q4 Medicine Pub Date : 2022-12-26 DOI: 10.30702/ujcvs/22.30(04)/km052-8187
I. Kobza, Y. Mota, T. Kobza
Extracranial carotid artery aneurysm (ECAA) is a rare vascularpathology with reported incidence of 0.2-5.0% of all carotid artery surgical interventions. Most of ECAAs remain clinically asymptomatic, however, they can manifest in neurological symptoms as transient ischemic attack or stroke. The presence of a pulsating formation, swallowing disorders, signs of compression of cranial nerves may beindicative of the aneurysm growth, which is associated with higher risk of thromboembolic complications and less oftenwith rupture. Surgical treatment is a method of choice in symptomatic patients or in cases of the aneurysm growth and includes resection with arterial reconstruction, ligation of the artery or endovascular intervention. The aim. To improve the results of surgical treatment of ECAAs. Materials and methods. The results of clinical examination, laboratory, instrumental, intraoperative observations were analyzed in 39 patients (35 [89.7%] men and 4 [10.3%] women) with 44 ECAAs, who were admitted to the Vascular Surgery Department of Lviv Regional Clinical Hospital for the period from 2003 to 2022. To conϐirm the diagnosis of ECAA, preoperative instrumental examination included duplex ultrasonography and multispiral computed tomography angiography. Results. Etiological causes of ECAAs included: atherosclerosis (79.5%),ϐibromuscular dysplasia (7.7%), trauma (5.1%), previous operations in the neck region (5.1%) and infection (2.6%). The justiϐication of the choice of surgical tactics depended on the localization of aneurysm, concomitant carotid occlusive disease or pathological deviation of carotid arteries. Early results of surgical treatment were evaluated up to 30 days of the postoperative period. The postoperative complications included: transient ischemic attack in 1 (2.6%), ischemic stroke in 2 (5.1%), cranial nerve damages in 4 (10.3%), thrombosis of arterial reconstruction in 2 (5.1%), hematoma of postoperative wound in 4 (10.3%), infection of postoperative wound in 1 (2.6%) cases. Postoperative mortality was 2.6%. Conclusion. ECAA is a rare clinical disease that requires an active surgical approach to reduce the risk of ischemic stroke. Reconstructive surgery of ECAAs is a highly effective method of treatment that allows to achieve satisfactory results and prevent the development of severe complications.
颅外颈动脉动脉瘤(ECAA)是一种罕见的血管病变,在所有颈动脉手术中发病率为0.2-5.0%。大多数ECAAs临床无症状,但可表现为神经系统症状,如短暂性脑缺血发作或中风。搏动形成、吞咽障碍、颅神经压迫的迹象可能表明动脉瘤生长,这与血栓栓塞并发症的高风险相关,而破裂的风险较低。对于有症状的患者或动脉瘤生长的病例,手术治疗是一种选择,包括切除动脉重建、动脉结扎或血管内介入。的目标。目的:提高ECAAs的手术治疗效果。材料和方法。对2003 ~ 2022年在利沃夫地区临床医院血管外科收治的44例ECAAs患者39例(男性35例[89.7%],女性4例[10.3%])的临床检查、实验室、仪器及术中观察结果进行分析。为了conϐirm诊断ECAA,术前器械检查包括双超和多螺旋ct血管造影。结果。ECAAs的病因包括:动脉粥样硬化(79.5%)、ϐibromuscular发育不良(7.7%)、外伤(5.1%)、既往颈部手术(5.1%)和感染(2.6%)。手术策略的选择justiϐication取决于动脉瘤的定位、颈动脉合并闭塞性疾病或颈动脉的病理性偏离。术后30天评估手术治疗的早期结果。术后并发症:短暂性脑缺血发作1例(2.6%),缺血性脑卒中2例(5.1%),脑神经损伤4例(10.3%),动脉重建血栓形成2例(5.1%),术后创面血肿4例(10.3%),术后创面感染1例(2.6%)。术后死亡率为2.6%。结论。ECAA是一种罕见的临床疾病,需要积极的手术方法来降低缺血性卒中的风险。ECAAs的重建手术是一种非常有效的治疗方法,可以获得满意的结果并防止严重并发症的发生。
{"title":"Extracranial Carotid Artery Aneurysms: 20-Year Experience of Surgical Management","authors":"I. Kobza, Y. Mota, T. Kobza","doi":"10.30702/ujcvs/22.30(04)/km052-8187","DOIUrl":"https://doi.org/10.30702/ujcvs/22.30(04)/km052-8187","url":null,"abstract":"Extracranial carotid artery aneurysm (ECAA) is a rare vascularpathology with reported incidence of 0.2-5.0% of all carotid artery surgical interventions. Most of ECAAs remain clinically asymptomatic, however, they can manifest in neurological symptoms as transient ischemic attack or stroke. The presence of a pulsating formation, swallowing disorders, signs of compression of cranial nerves may beindicative of the aneurysm growth, which is associated with higher risk of thromboembolic complications and less oftenwith rupture. Surgical treatment is a method of choice in symptomatic patients or in cases of the aneurysm growth and includes resection with arterial reconstruction, ligation of the artery or endovascular intervention. \u0000The aim. To improve the results of surgical treatment of ECAAs. \u0000Materials and methods. The results of clinical examination, laboratory, instrumental, intraoperative observations were analyzed in 39 patients (35 [89.7%] men and 4 [10.3%] women) with 44 ECAAs, who were admitted to the Vascular Surgery Department of Lviv Regional Clinical Hospital for the period from 2003 to 2022. To conϐirm the diagnosis of ECAA, preoperative instrumental examination included duplex ultrasonography and multispiral computed tomography angiography. \u0000Results. Etiological causes of ECAAs included: atherosclerosis (79.5%),ϐibromuscular dysplasia (7.7%), trauma (5.1%), previous operations in the neck region (5.1%) and infection (2.6%). The justiϐication of the choice of surgical tactics depended on the localization of aneurysm, concomitant carotid occlusive disease or pathological deviation of carotid arteries. Early results of surgical treatment were evaluated up to 30 days of the postoperative period. The postoperative complications included: transient ischemic attack in 1 (2.6%), ischemic stroke in 2 (5.1%), cranial nerve damages in 4 (10.3%), thrombosis of arterial reconstruction in 2 (5.1%), hematoma of postoperative wound in 4 (10.3%), infection of postoperative wound in 1 (2.6%) cases. Postoperative mortality was 2.6%. \u0000Conclusion. ECAA is a rare clinical disease that requires an active surgical approach to reduce the risk of ischemic stroke. Reconstructive surgery of ECAAs is a highly effective method of treatment that allows to achieve satisfactory results and prevent the development of severe complications.","PeriodicalId":33680,"journal":{"name":"Ukrayins''kii zhurnal sertsevosudinnoyi khirurgiyi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48172555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Features of the Blood Supply of Cardiac Myxoma which Can Cause Bleeding 心脏黏液瘤致出血的血供特征
Q4 Medicine Pub Date : 2022-12-26 DOI: 10.30702/ujcvs/22.30(04)/vi060-122127
R. M. Vitovskyi, V. Isaienko, Oleksandr A. Pishchurin, A. R. Vitovskyi, Maryna M. Serdiuk, Valentina P. Zakharova
With a mortality rate of 1 % to 5 %, surgical treatment of cardiac myxomas (CM) may be complicated by the development of intra- or postoperative bleeding, among other things. The aim. To present an unusual case of surgical treatment of left atrial myxoma with the occurrence of intraoperative bleeding, which was due to extremely rare features of the coronary circulation with a special blood supply to the base of the CM. Case report. Female patient R., 65 years old, case record No.3686, was admitted to the National Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine with diagnosis of CM. Coronary angiography revealed unique features of coronary circulation: an arteriovenous malformation from the distal parts of the circumflex branch of the left coronary artery with discharge into the right parts of the heart was revealed. On 9/20/2022, urgent operation of resection of the myxoma of the left atrium (LA) was performed. After removal of the myxoma and sealing of the heart, accumulation of arterial blood was found in the area of the inferior vena cava (IVC) and the interatrialsulcus. Revision of the left atrium cavity was performed again:all intracardiac sutures in the area of the myxoma base were duplicated. After repeated resealing of the heart chambers, bleeding from the IVC region stopped after administration of protamine sulfate and tight tamponade of the space under the IVC. Tampons were removed from the pericardial cavity after 72 hours. Results. The source of the bleeding could be the site of the malformation of the coronary arteries, which is a tangle of small vessels located in the projection of the base of the myxoma below the point where the IVC meets the right atrium. During the histological examination of the myxoma, large full-blood vessels of the sinusoidal type were revealed, around which, due to damage to their thin walls, hematomas formed, giving the tumor a spotted appearance. The peculiarity of this tumor was the presence of a very large vascular plexus at its base; it had the appearance of a cluster of sections of numerous, different-sized, deformed and remodeled arteries. These data were confirmed by coronary angiography. Conclusions. Studying the data of coronary angiography with the analysis offeatures of localization of coronary arteries, as well as the presence of possible coronary malformations, can provide information that allows predicting the possibility of their damage, especially in the case of localization in the place of possible surgical manipulation. In the event of bleeding, one of the optimal methods of its elimination is the use of long-term tamponade.
心脏粘液瘤(CM)的死亡率为1%至5%,手术治疗可能会因术中或术后出血等因素而变得复杂。目标。本文报告一例罕见的左心房粘液瘤手术治疗中出血的病例,该病例是由于冠状动脉循环的极为罕见的特征,冠状动脉底部有特殊的血液供应。病例报告。女患者R,65岁,病例记录第3686号,被诊断为CM,入住乌克兰国家医学科学院国家阿莫索夫心血管外科研究所。冠状动脉造影显示了冠状动脉循环的独特特征:显示了一个从左冠状动脉回旋支远端到心脏右侧的动静脉畸形。2022年9月20日,进行了左心房粘液瘤切除的紧急手术。切除黏液瘤并封闭心脏后,在下腔静脉(IVC)和肠间溃疡区域发现动脉血积聚。再次对左心房进行翻修:粘液瘤基底部区域的所有心内缝线均重复。在反复重新密封心室后,在给予鱼精蛋白硫酸盐并紧密填塞IVC下方的空间后,IVC区域的出血停止。72小时后从心包腔内取出填塞物。后果出血的来源可能是冠状动脉畸形的部位,冠状动脉畸形是位于粘液瘤基底突出部IVC与右心房交界处下方的一团小血管。在粘液瘤的组织学检查中,发现了正弦型的完整大血管,由于薄壁受损,血管周围形成了血肿,使肿瘤呈现斑点状。这种肿瘤的特点是在其底部有一个非常大的血管丛;它的外观是由许多不同大小、变形和重塑的动脉组成的一组切片。这些数据经冠状动脉造影证实。结论。通过对冠状动脉定位特征以及可能存在的冠状动脉畸形的分析,研究冠状动脉造影数据,可以提供预测其损伤可能性的信息,特别是在可能的手术操作位置进行定位的情况下。在出血的情况下,消除出血的最佳方法之一是使用长期填塞。
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引用次数: 0
The Choice of Optimally Necessary Devices for Endovascular Treatment of Coarctation of the Aorta 血管内治疗主动脉缩窄最佳装置的选择
Q4 Medicine Pub Date : 2022-12-26 DOI: 10.30702/ujcvs/22.30(04)/cy062-6672
B. Cherpak, Nataliia S. Yaschuk, Y. V. Yermolovych, Oleksandr S. Golovenko, Yuri Panichkin
The aim. To determine the optimally necessary devices for endovascular stenting of coarctation of the aorta (CoA), considering the anatomical features of the defect and the age of the patient. Materials and methods. Examination and endovascular treatment of 189 patients aged 5 to 60 years with CoA of different anatomical and morphological variants was performed. Results and discussion. We presented the clinical features of different anatomical andmorphological variants of CoA. Endovascular treatment of CoA with stenting is considered the best method for adolescents and adults, due to the lower risk of aneurysm formation compared to balloon angioplasty. We were able to successfully reduce the invasive pressure gradient in patients of different ages and to establish dependence of the frequency of complications on the type of the stent used. There were no cases of in-hospital death. The effectiveness of the intervention was 99.4 %. All the patients were discharged from the hospital in good condition 3-7 days (3.3 ± 1.9 days) after the procedure. Currently, 95.7 % are being followed up. During the 5-year follow-up period, 1 patient died due to concomitant heart failure, heart rhythm disturbances (atrial fibrillation) and mitral insufficiency. There were 10.1 % patients (n = 19) with complications: 4.9 % (n = 4) with open-cell stents, 12.1 % (n = 13) with closed-cell stents, 2.2 % (n = 4) with stent-grafts, 7.9 % (n = 16) with uncovered stents. The frequency of reinterventions was 45.0 % in patients older than 25 years, 37.2 % in those aged 5-18 years and 17.6 % in those aged 19-25 years. Conclusions. The choice of optimally necessary devices for endovascular stenting of the aorta is recommended to be carried out considering the anatomical features of the defect and the age of the patient.
的目标。考虑到主动脉缩窄(CoA)的解剖特征和患者的年龄,确定血管内支架植入术的最佳设备。材料和方法。本文对189例5 ~ 60岁不同解剖形态变异的CoA患者进行了检查和血管内治疗。结果和讨论。我们介绍了不同解剖形态变异的CoA的临床特征。血管内支架治疗CoA被认为是青少年和成人的最佳方法,因为与球囊血管成形术相比,动脉瘤形成的风险较低。我们能够成功地降低不同年龄患者的侵入性压力梯度,并建立并发症频率与所使用的支架类型的依赖关系。没有院内死亡病例。干预有效率为99.4%。术后3 ~ 7天(3.3±1.9天)出院,病情良好。目前,95.7%的患者正在接受随访。5年随访期间,1例患者因合并心力衰竭、心律失常(心房颤动)和二尖瓣功能不全死亡。10.1%的患者(n = 19)出现并发症:开放细胞支架4.9% (n = 4),封闭细胞支架12.1% (n = 13),支架移植物2.2% (n = 4),无覆盖支架7.9% (n = 16)。25岁以上患者再干预率为45.0%,5-18岁为37.2%,19-25岁为17.6%。结论。考虑到缺损的解剖特征和患者的年龄,建议选择血管内支架植入术所需的最佳设备。
{"title":"The Choice of Optimally Necessary Devices for Endovascular Treatment of Coarctation of the Aorta","authors":"B. Cherpak, Nataliia S. Yaschuk, Y. V. Yermolovych, Oleksandr S. Golovenko, Yuri Panichkin","doi":"10.30702/ujcvs/22.30(04)/cy062-6672","DOIUrl":"https://doi.org/10.30702/ujcvs/22.30(04)/cy062-6672","url":null,"abstract":"The aim. To determine the optimally necessary devices for endovascular stenting of coarctation of the aorta (CoA), considering the anatomical features of the defect and the age of the patient. \u0000Materials and methods. Examination and endovascular treatment of 189 patients aged 5 to 60 years with CoA of different anatomical and morphological variants was performed. \u0000Results and discussion. We presented the clinical features of different anatomical andmorphological variants of CoA. Endovascular treatment of CoA with stenting is considered the best method for adolescents and adults, due to the lower risk of aneurysm formation compared to balloon angioplasty. We were able to successfully reduce the invasive pressure gradient in patients of different ages and to establish dependence of the frequency of complications on the type of the stent used. There were no cases of in-hospital death. The effectiveness of the intervention was 99.4 %. All the patients were discharged from the hospital in good condition 3-7 days (3.3 ± 1.9 days) after the procedure. Currently, 95.7 % are being followed up. During the 5-year follow-up period, 1 patient died due to concomitant heart failure, heart rhythm disturbances (atrial fibrillation) and mitral insufficiency. There were 10.1 % patients (n = 19) with complications: 4.9 % (n = 4) with open-cell stents, 12.1 % (n = 13) with closed-cell stents, 2.2 % (n = 4) with stent-grafts, 7.9 % (n = 16) with uncovered stents. The frequency of reinterventions was 45.0 % in patients older than 25 years, 37.2 % in those aged 5-18 years and 17.6 % in those aged 19-25 years. \u0000Conclusions. The choice of optimally necessary devices for endovascular stenting of the aorta is recommended to be carried out considering the anatomical features of the defect and the age of the patient.","PeriodicalId":33680,"journal":{"name":"Ukrayins''kii zhurnal sertsevosudinnoyi khirurgiyi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69577023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case of Dilated Cardiomyopathy in Combination with Left Atrial Myxoma and Left Atriomegaly (Rare Clinical Case) 扩张型心肌病合并左心房粘液瘤和左心房肥大1例(罕见临床病例)
Q4 Medicine Pub Date : 2022-12-26 DOI: 10.30702/ujcvs/22.30(04)/pb059-4752
V. Popov, O. Bolshak, V. Boukarim, Olena V. Khoroshkovata, O. M. Gurtovenko
Case description. A 41-year-old male patient F. was admitted to the Department ofSurgical Treatment of Ac-quired Heart Diseases of the National Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine with a diagnosis: Dilated cardiomyopathy. Mitral-tricuspid insufϐiciency. Left atrial myxoma. Left atriomegaly. Pulmonary hypertension. The patient was operated with heart failure symptoms of NYHA functional class IV. After a week of medical preparation and additional examination,the patient was successfully operated on (remov-al of the left atrial myxoma, imposition of support rings on the left and right atrioventricular openings, paraanular plicacy of the left atrium). The postoperative period proceededwithout signiϐicant complications. On the 12th day after the operation, the patient was discharged in satisfactorycondition. In the remote period the patient died suddenly 3 years later. Conclusion. Taking into account the initial serious condition of a patient with advanced heart disease with a reduced left ventricular ejection fraction, left atriomegaly (7.8 cm), pulmonary hypertension (50 mm Hg) and comorbidities, complex reconstruction of the left heart in atriomegaly and ventriculomegaly leads to an improvement in the functional state of the myocardium and morphometric indicators of left atrium and left ventricular ejection fraction.
案例描述。41岁男性患者F.被乌克兰国家医学科学院国立阿莫索夫心血管外科研究所收治为急性心脏病外科治疗科,诊断为扩张性心肌病。Mitral-tricuspid insufϐ角度。左心房黏液瘤。左心房肥大。肺动脉高压。患者手术时心衰竭症状为NYHA功能四级。经过一周的医学准备和附加检查,患者成功手术(切除左心房黏液瘤,在左右房室开口上施加支撑环,左心房环旁并发症)。术后无signiϐicant并发症。术后第12天,患者出院,病情满意。在偏远地区,患者在3年后突然死亡。结论。考虑到晚期心脏病患者初始病情严重,左室射血分数降低,左心房增大(7.8 cm),肺动脉高压(50 mm Hg)及合并症,左心复杂重建左心房和心室增大导致心肌功能状态及左心房和左心室射血分数形态学指标改善。
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引用次数: 1
Experience of Endovascular Treatment of Pulmonary Artery Atresia 肺动脉闭锁的血管内治疗经验
Q4 Medicine Pub Date : 2022-09-26 DOI: 10.30702/ujcvs/22.30(03)/id040-7682
E. Imanov, I. Ditkivskyy, O. Plyska, O. Mazur, Artemiia O. Sloboda
The aim. To analyze the results of the use of endovascular treatments for pulmonary artery atresia (PAA). Materials and methods. Treatment of this heart defect at the National Amosov Institute of Cardiovascular Surgery of the NAMS of Ukraine with application of endovascular methods began in 2006. Since then, 138 patients were operated, 57 of them female (41.3%) and 81 (58.6%) were male. Endovascular methods were used in 23 patients, and 115 patients underwent open-heart surgery. The mean length of hospital stay was 25±16.3 days. Of 115 patients who underwent open-heart surgery, 62 (54%) were male and 53 (46%) were female. On the day of surgery, the mean age of these patients was 607.8±1023.7 days, mean weight was 8.8±8.1 kg. The average length of hospital stay was 26±18.6 (maximum 215, minimum 5). Of 23 patients who underwent endovascular surgery, 18 (77%) were male and 5 (23%) were female. The mean age on the day of surgery was 220.5±650.2 days, mean weight was 5.0±4.4 kg. The mean length of hospital stay was 22±5.7 days (maximum 34, minimum 4). In the treatment of PAA, a stepwise procedure is used, correcting part of the defect at each stage and thereby reducing the traumaticity of the operation. In our case, correction of the defect was performed on the open heart and using endovascular methods of treatment. After endovascular interventions, no fatal effects were observed. Open-heart surgery was performed in case if endovascular interventions could not be performed. The condition of such patients was usually more severe. It should also be noted that the open-heart surgery itself is a serious trauma to the body. Due to the above, postoperative period in this group of patients more often proceeded with complications. Due to more severe preoperative condition of the patients and surgical trauma, in some cases of open-heart interventions, some patients did not recover after surgery. As a result, the total mortality in the group of patients who underwent open-heart surgery was 13.0%. In addition, in 7 cases, such surgery was supplemented by the Rashkind procedure. In case of recurrent surgery after 6 months, stenting of patent ductus arteriosus was performed. Repeated surgical interventions were accompanied by the improvement of the condition and the patients were discharged from the clinic in satisfactory condition. Conclusions. PAA is one of the most complex congenital pathologies of the heart and main vessels, and therefore preservation of such a newborn depends on the preservation of patent ductus arteriosus. Endovascular surgery for PAA is the operation of choice that allows to prepare the patient for the next stage of treatment, including open-heart surgery. Endovascular interventions in PAA are minimally invasive, which increases the chances of patients with complicated anatomy to survive despite their serious condition on admission to the hospital.
目标。分析肺动脉闭锁(PAA)血管内治疗的效果。材料和方法。乌克兰NAMS国家阿莫索夫心血管外科研究所于2006年开始应用血管内方法治疗这种心脏缺陷。自那以后,138名患者接受了手术,其中57名为女性(41.3%),81名为男性(58.6%)。23名患者采用血管内方法,115名患者接受了心脏直视手术。平均住院时间为25±16.3天。在115名接受心脏直视手术的患者中,62名(54%)为男性,53名(46%)为女性。手术当天,这些患者的平均年龄为607.8±1023.7天,平均体重为8.8±8.1公斤。平均住院时间为26±18.6(最多215天,最少5天)。在接受血管内手术的23名患者中,18名(77%)为男性,5名(23%)为女性。手术当天的平均年龄为220.5±650.2天,平均体重为5.0±4.4公斤。平均住院时间为22±5.7天(最多34天,最少4天)。在PAA的治疗中,采用逐步程序,在每个阶段纠正部分缺陷,从而减少手术的创伤。在我们的病例中,缺损的矫正是在开放的心脏上进行的,并使用血管内治疗方法。血管内介入治疗后,未观察到致命影响。如果不能进行血管内介入治疗,则进行心脏直视手术。这些病人的情况通常更为严重。还应该注意的是,心脏直视手术本身对身体来说是一种严重的创伤。由于上述原因,这组患者术后更经常出现并发症。由于患者的术前病情更为严重,加上手术创伤,在某些情况下进行了心脏直视干预,一些患者在手术后并没有恢复。结果,接受心脏直视手术的患者组的总死亡率为13.0%。此外,在7例患者中,此类手术辅以Rashkind手术。在6个月后再次手术的情况下,进行动脉导管未闭支架置入术。反复的手术干预伴随着病情的改善,患者以满意的状态出院。结论。PAA是心脏和主要血管最复杂的先天性病变之一,因此新生儿的保存取决于动脉导管未闭的保存。PAA的血管内手术是一种选择的手术,可以让患者为下一阶段的治疗做好准备,包括心脏直视手术。PAA的血管内干预是微创的,这增加了解剖结构复杂的患者的生存机会,尽管他们入院时病情严重。
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Ukrayins''kii zhurnal sertsevosudinnoyi khirurgiyi
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