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A Case of Epstein-Barr Virus-Positive Diffuse Large B-Cell Lymphoma Occurring in Thyroid Gland 一例发生在甲状腺的爱泼斯坦-巴氏病毒阳性弥漫性大 B 细胞淋巴瘤病例
Pub Date : 2023-11-30 DOI: 10.21593/kjhno/2023.39.2.59
Hyunseok Choi, Dongha Kim, Jaeman Park, Jeong-Soo Woo, Jae-Gu Cho
Epstein-Barr virus positive diffuse large B-cell lymphoma is very rare malignant tumor in thyroid gland. Compared to Epstein-Barr virus negative diffuse large B-cell lymphoma, it tends to have more extranodal involvement, does not respond to chemoimmunotherapy well, and has worse prognosis. We have encountered a patient with Epstein-Barr virus positive diffuse large B-cell lymphoma of thyroid gland in 75-year-old female presenting with aggravating dyspnea and neck pain.
Epstein-Barr病毒阳性弥漫大B细胞淋巴瘤是一种非常罕见的甲状腺恶性肿瘤。与Epstein-Barr病毒阴性的弥漫大B细胞淋巴瘤相比,它往往有更多的结节外受累,对化疗免疫治疗反应不佳,预后较差。我们曾接诊过一名75岁女性甲状腺弥漫大B细胞淋巴瘤患者,她因呼吸困难和颈部疼痛加重而就诊。
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引用次数: 0
A Case of Follicular Dendritic Cell Sarcoma in Submandibular Region 颌下滤泡树突状细胞肉瘤病例
Pub Date : 2023-11-30 DOI: 10.21593/kjhno/2023.39.2.41
Jae Ho Yoo, Dong Won Lee, Jeong-Kyu Kim
Follicular dendritic cell sarcoma (FDCS) is rare lymphoid sarcoma occurs anywhere in body, mostly in lymph nodes. Sixty-two-year-old man presented left submandibular gland region mass for 5 months. Mass excision with submandibular gland resection was performed. Histopathology showed proliferation of spindle and ovoid cells with storiform arrangement which were positive for CD21, CD23, Vimentin, Ki-67, suggested FDCS in submandibular gland region lymph node. Tumor size was 3cm with no involvement of resection margin, nor cellular atypia and necrosis, so regular follow up was performed. After 4 years, new enhancing mass in left submandibular area was found. Wide excision of mass with neck dissection on left level I-III was performed. Histopathology confirmed recurrence of FDCS. The patient underwent radiation therapy from left mandible to hyoid area. After 2 years, new nodule was found in left lung upper lobe, and wedge resection confirmed metastasis of FDCS. The patient is on adjuvant chemotherapy.
滤泡树突状细胞肉瘤(Follicular dendritic cell sarcoma,FDCS)是一种罕见的淋巴肉瘤,可发生在身体的任何部位,多见于淋巴结。六十二岁的男性左侧颌下腺区肿块已有五个月。患者接受了肿块切除术和颌下腺切除术。组织病理学显示,颌下腺淋巴结内有纺锤形和卵圆形细胞增生,呈星状排列,CD21、CD23、Vimentin、Ki-67均呈阳性,提示为FDCS。肿瘤大小为 3 厘米,没有累及切除边缘,也没有细胞不典型性和坏死,因此进行了定期随访。4 年后,发现左侧颌下腺区域有新的增大肿块。医生对肿块进行了大范围切除,并在左侧Ⅰ-Ⅲ水平进行了颈部解剖。组织病理学证实 FDCS 复发。患者接受了从左下颌骨到舌骨区的放射治疗。两年后,在左肺上叶发现新的结节,楔形切除证实 FDCS 转移。患者正在接受辅助化疗。
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引用次数: 0
Pigmented Pilomatricoma on the Ear Resembling Vascular Tumor before Surgery: A Case Report 手术前与血管瘤相似的耳部色素痣:病例报告
Pub Date : 2023-11-30 DOI: 10.21593/kjhno/2023.39.2.31
Seok Beom Lim, In Chang Koh, Hoon Kim, Kun Young Kwon, Soo Yeon Lim
Pilomatricoma is characterized by a semi-transparent epidermis, especially pigmented pilomatricoma, containing melanocytes in basaloid cells, which are dark and purple, resembling vessel-derived skin masses. If the vascularity at doppler ultrasound is high before surgery, it may be misdiagnosed.A 10-year-old female patient visited our clinic because of a mass in the right ear triangular fossa. Ultrasonography was performed, and a vascular-origin tumor was suspected because of the high vascularity. The excised mass was diagnosed as pigmented pilomatricoma by a pathologist.Pilomatricoma is mistaken for other masses owing to its various phenotypes. A misdiagnosis can lead to misdirected strategies which can cause delayed treatment and can result in an increase in the size of the pilomatricoma, making the sequalae of surgery more complicated. For proper treatment, careful examination and evaluation are required before surgery.
朝天鼻瘤的特点是表皮半透明,尤其是色素朝天鼻瘤,基底细胞中含有黑素细胞,呈深紫色,类似血管源性皮肤肿块。如果术前多普勒超声显示血管较多,可能会被误诊。一名 10 岁女性患者因右耳三角窝肿块就诊。一名 10 岁的女性患者因右耳三角窝肿块来我院就诊,医生为其进行了超声检查,因其血管丰富,怀疑为血管源性肿瘤。病理学家诊断切除的肿块为色素性朝天鼻瘤。由于朝天鼻瘤的表型多种多样,因此容易被误诊为其他肿块。误诊会导致错误的治疗策略,从而延误治疗,并可能导致朝天鼻瘤增大,使手术后遗症变得更加复杂。为了正确治疗,手术前必须进行仔细检查和评估。
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引用次数: 0
A Case of Solitary Fibrous Tumor of the Chin 下巴单发纤维瘤病例
Pub Date : 2023-11-30 DOI: 10.21593/kjhno/2023.39.2.35
Taesik Kim, Sung Gyun Jung, In Pyo Hong, Young Joong Hwang
Solitary fibrous tumor (SFT), which was initially believed to be a subtype of mesothelioma, has been reported to occur outside the pleura. In the head and neck region, it primarily manifests in the oral or nasal cavity, with rare occurrences in the facial region. A 40-year-old woman visited our hospital with a mass on her chin. Prior to surgery, involuntary movement was observed in the ipsilateral corner of the mouth upon palpation of the mass. Special care was taken during the surgical procedure to avoid damaging the facial nerve. The mass was excised, and histological examination and immunohistochemical analysis confirmed the diagnosis of an SFT. Here, we present the first reported case of an SFT diagnosed in a jaw mass in Korea. The objective of this study was to highlight the importance of the diagnostic accuracy of SFTs in lower jaw masses.
孤立性纤维瘤(SFT)最初被认为是间皮瘤的一种亚型,但有报道称它发生在胸膜以外的部位。在头颈部,它主要表现在口腔或鼻腔,面部也有罕见病例。一名 40 岁女性因下巴肿块来我院就诊。手术前,触诊肿块时发现同侧嘴角有不自主运动。手术过程中特别注意避免损伤面神经。肿块被切除,组织学检查和免疫组化分析证实了 SFT 的诊断。在此,我们报告了韩国首例在下颌肿块中诊断出 SFT 的病例。本研究旨在强调下颌肿块中 SFT 诊断准确性的重要性。
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引用次数: 0
A Case of Lymphoepithelial Cyst Mimicking Cervical Plexus Schwannoma 一个模仿宫颈丛神经纤维瘤的淋巴上皮囊肿病例
Pub Date : 2023-11-30 DOI: 10.21593/kjhno/2023.39.2.49
Jeong Hwan Kim, Byung Jae Kang, Min Suk Kim, Hong Jin Kim, Ye Hwan Lee, HwaEun Oh, K. Oh, Soon Young Kwon
Neck masses can have various origins and diverse presentations, making accurate diagnosis challenging. Schwannomas and lymphoepithelial cysts are commonly encountered neck tumors, and it is hard to get differential diagnosis. A 50-year-old woman presented with a progressively enlarging right neck mass discovered five years ago. Upon examination, a 3 cm firm, non-tender, and mobile tumor was found in the right neck level II region. Imaging studies suggested a tumor originating from the cervical sympathetic chain. The patient underwent a resection of the tumor under general anesthesia. Postoperative follow-up showed no complications or signs of recurrence. However, contrary to the initial suspicion of a schwannoma, the final pathological examination revealed a lymphoepithelial cyst. In this paper, we present a case of a cervical lymphoepithelial cyst misdiagnosed as a schwannoma, aiming to compare the clinical and histological characteristics of these two tumors and provide insights into appropriate diagnosis and management.
颈部肿块的来源和表现多种多样,因此准确诊断具有挑战性。许旺瘤和淋巴上皮囊肿是常见的颈部肿瘤,很难进行鉴别诊断。一名 50 岁的妇女五年前发现右颈部肿块逐渐增大。经检查发现,右颈部二级区域有一个 3 厘米的坚硬、无触痛、可移动的肿瘤。影像学检查显示肿瘤源自颈交感神经链。患者在全身麻醉下接受了肿瘤切除术。术后随访显示无并发症或复发迹象。然而,与最初怀疑的分裂瘤相反,最终的病理检查却发现了淋巴上皮囊肿。本文介绍了一例被误诊为分裂瘤的宫颈淋巴上皮囊肿病例,旨在比较这两种肿瘤的临床和组织学特征,为适当的诊断和处理提供见解。
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引用次数: 0
An Ethmoid Sinus Ewing Sarcoma with Exophthalmos in A 21-Year-Old Male 一名 21 岁男性的乙状窦尤文肉瘤伴眼球外翻
Pub Date : 2023-11-30 DOI: 10.21593/kjhno/2023.39.2.55
Youngrok Jo, Youn Jin Cho, Ju Yeon Pyo, So Yeon Yoon, Keejae Song
Ewing sarcoma is a rare tumor in head and neck area. We demonstrate a rare case of sinonasal Ewing sarcoma initially suspected as olfactory neuroblastoma. After the surgery and immunohistochemical studies, it was accurately diagnosed as Ewing sarcoma. We would like to emphasize the possibility that Ewing sarcoma may originate from the head and neck area, and hence, it is important to use appropriate techniques for accurate diagnosis and treatment.
尤文肉瘤是头颈部的一种罕见肿瘤。我们展示了一例罕见的鼻窦尤文肉瘤病例,起初怀疑是嗅神经母细胞瘤。经过手术和免疫组化检查后,被准确诊断为尤文肉瘤。我们要强调的是,尤文肉瘤可能起源于头颈部,因此,使用适当的技术进行准确诊断和治疗非常重要。
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引用次数: 0
Surgical Excision and Reconstruction in Oral Cavity Cancer 口腔癌的手术切除与重建
Pub Date : 2023-05-31 DOI: 10.21593/kjhno/2023.39.1.11
Soon-Hyun Ahn
The primary treatment of oral cavity cancer is still surgery. By discussing the surgical treatment of oral cavity cancer, the basic concept of head and neck surgery could be thoroughly reviewed. The oral cavity is defined as the hard palate and the anterior 2/3 of the tongue. With appropriate reconstruction, most defects can be repaired without a significant change in quality of life, unlike in the oropharynx or hypopharynx, where aspiration problems frequently occur. The selection of a surgical approach that can provide an appropriate field of view to obtain a resection margin of 5 mm or more has become the core of head and neck surgery. The role of prophylactic neck dissection is also well established in oral cavity cancer patients. Mandibulotomy for access to the oral cavity or mandibulectomy due to cancer invasion requires bony surgical techniques, and reconstruction also requires bone tissue reconstruction techniques as well as soft tissue. Therefore, oral cancer surgery is the most important primary area where all techniques of head and neck surgery are mobilized.
口腔癌的主要治疗方法仍然是手术。通过对口腔癌手术治疗的探讨,对头颈部外科的基本概念进行了全面的回顾。口腔被定义为硬腭和舌头前三分之二。通过适当的重建,大多数缺陷都可以修复,而不会对生活质量产生重大影响,这与口咽或下咽经常发生误吸问题不同。选择合适的手术入路以获得5mm或更大的切除边缘已成为头颈部手术的核心。预防性颈部清扫在口腔癌患者中的作用也得到了很好的证实。为了进入口腔而进行的下颌切开术或因肿瘤侵袭而进行的下颌切开术需要骨外科技术,重建也需要骨组织重建技术和软组织。因此,口腔癌手术是调动头颈部外科所有技术的最重要的初级领域。
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引用次数: 0
A Large Intermuscular Lipoma of the Posterolateral Neck: A Case Report 颈部后外侧大肌间脂肪瘤1例
Pub Date : 2023-05-31 DOI: 10.21593/kjhno/2023.39.1.19
Kyung Suk Lee, Jae Bong Shin, Jun Sik Kim, Gi Cheol Do, M. Kim, N. Kim
Lipomas are a common soft-tissue tumor of mesenchymal origin, but intermuscular lipomas are very infrequently found especially in the cervical region. Although lipoma itself rarely causes complications, an accurate diagnosis and appropriate treatment are important. Surgical excision is indicated for deep lipomas that are 5 cm or larger, grow, or are accompanied by symptoms such as pain. It is also important to differentiate malignant tumors through pathological examination. Since the size of the lipoma was large, lipoma was divided into several pieces to successful removal, and the patient in this case showed successful recovery after surgery.
脂肪瘤是一种常见的软组织间质肿瘤,但肌间脂肪瘤很少发现,特别是在颈部。虽然脂肪瘤本身很少引起并发症,但准确的诊断和适当的治疗是重要的。当深度脂肪瘤大于或大于5cm、生长或伴有疼痛等症状时,应行手术切除。通过病理检查鉴别恶性肿瘤也很重要。由于脂肪瘤体积较大,我们将脂肪瘤分成几块成功切除,本例患者术后恢复顺利。
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引用次数: 0
Efficacy of Picibanil Sclerotherapy in Treatment of Plunging Ranula 匹比班尼硬化疗法治疗突发性牛痘的疗效观察
Pub Date : 2023-05-31 DOI: 10.21593/kjhno/2023.39.1.15
Hyun Taek Jung, Sangmok Lee, Yunbin Nam, Jang Won Oh, H. Shin, Ji-Hoon Kim
A plunging ranula is a pseudocyst caused by mucus secreted from the sublingual glands, and it is mainly observed on the mouth floor. Nowadays, sclerotherapy using picibanil has been performed instead of invasive surgical treatment, and studies are reporting safe and effective outcomes. In our study, more than 92% of the 25 patients had marked response after picibanil sclerotherapy, and no serious complications were observed. Picibanil sclerotheraphy can be considered as the primary treatment of plunging ranula for patients who refuse surgery under general anaesthesia.
下陷小瘘管是由舌下腺分泌粘液引起的假性囊肿,主要见于口底。如今,使用吡吡尼尔进行硬化治疗已取代侵入性手术治疗,研究报告了安全有效的结果。在我们的研究中,25例患者经匹吡地尼硬化治疗后,92%以上的患者有明显的缓解,未见严重的并发症。对于全身麻醉下拒绝手术的患者,可考虑采用比吡班尼硬化疗法作为静脉瘘的主要治疗方法。
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引用次数: 0
A Case of Intra-thyroidal Parathyroid Adenoma Confirmed by Intraoperative Near-infrared Autofluorescence 术中近红外自体荧光诊断甲状旁腺瘤1例
Pub Date : 2023-05-31 DOI: 10.21593/kjhno/2023.39.1.53
D. Choi, J. S. Cha, Y. Kim, H. Lee, K. Lee
In general, the anatomical location and number of parathyroid glands are well known, but they are often found in a variety of locations, making it difficult to find parathyroid glands during surgery. Besides Intra-thyroidal parathyroid adenoma is extremely rare case, and it is harder to identify in surgery. We encountered a 51-year-old patient with a thyroid nodule. The results of the additional blood test and the Tc-99m MIBI were combined to determine that the left lower lobe parathyroid adenoma was highly likely. This patient was treated with left thyroid lobectomy with parathyroid identification using Near-infrared (NIR) imaging. Afterwards, the biopsy confirmed that it was a parathyroid adenoma, and has since been monitored through outpatient observation without any problem. We present this rare case with a review of related literatures.
一般来说,甲状旁腺的解剖位置和数量是众所周知的,但它们往往出现在各种各样的位置,这使得在手术中很难找到甲状旁腺。此外,甲状旁腺瘤是一种极为罕见的病例,在手术中较难确诊。我们遇到了一个51岁的甲状腺结节患者。结合额外的血液检查和Tc-99m MIBI的结果,确定左下叶甲状旁腺瘤的可能性很大。该患者接受左甲状腺叶切除术,并使用近红外(NIR)成像识别甲状旁腺。之后,活检证实为甲状旁腺瘤,此后通过门诊观察进行监测,没有任何问题。我们将此罕见病例与相关文献作一回顾。
{"title":"A Case of Intra-thyroidal Parathyroid Adenoma Confirmed by Intraoperative Near-infrared Autofluorescence","authors":"D. Choi, J. S. Cha, Y. Kim, H. Lee, K. Lee","doi":"10.21593/kjhno/2023.39.1.53","DOIUrl":"https://doi.org/10.21593/kjhno/2023.39.1.53","url":null,"abstract":"In general, the anatomical location and number of parathyroid glands are well known, but they are often found in a variety of locations, making it difficult to find parathyroid glands during surgery. Besides Intra-thyroidal parathyroid adenoma is extremely rare case, and it is harder to identify in surgery. We encountered a 51-year-old patient with a thyroid nodule. The results of the additional blood test and the Tc-99m MIBI were combined to determine that the left lower lobe parathyroid adenoma was highly likely. This patient was treated with left thyroid lobectomy with parathyroid identification using Near-infrared (NIR) imaging. Afterwards, the biopsy confirmed that it was a parathyroid adenoma, and has since been monitored through outpatient observation without any problem. We present this rare case with a review of related literatures.","PeriodicalId":336823,"journal":{"name":"Korean Society for Head and Neck Oncology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132695142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Korean Society for Head and Neck Oncology
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