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Public Trust in the Effectiveness of the Covid-19 Vaccine in Liliba Village, Oebobo District, Kupang City Kupang市Oebobo区Liliba村公众对新冠肺炎疫苗有效性的信任
Pub Date : 2022-06-27 DOI: 10.31965/infokes.vol20.iss1.588
Y. M. V. B. Aty, Pius Selasa, Marselina Bende Molina, Rohana Mochsen, Nantiya Pupuh, Panyada Cholsakhon
The Covid-19 pandemic has continued to develop in Indonesia since the beginning of 2020. The incidence and death rates continue to increase from day to day. Various efforts were made to stop the spread of the deadly Covid-19. One way to prevent and suppress the spread of infection with the virus is to vaccinate. The role of the vaccine is to provide immunity. Many people in the city of Kupang do not believe in the effectiveness of the Covid-19 vaccine, so they do not want to be vaccinated. The objective of this study is to describe the level of public confidence in the effectiveness of the Covid-19 vaccine in Liliba Village, Oebobo District, Kupang City. The research method is quantitative with a descriptive study research design. The population is people who live in the Liliba sub-district, Oebobo district, Kupang City. The sample was 106 people who were taken using the Cluster Simple Random Sampling technique. The results showed that the level of public confidence in the susceptibility of the Covid-19 vaccine was (89.6%), the seriousness of the vaccine's effectiveness (90.6%), the benefits of the vaccine (54.7%), and the perceived barriers (88.7%). This study revealed that the level of public confidence in the effectiveness of the Covid-19 vaccine in Liliba Village, Oebobo District, Kupang City is high.
自2020年初以来,新冠肺炎疫情在印度尼西亚继续发展。发病率和死亡率每天都在增加。为阻止致命的新冠肺炎的传播作出了各种努力。预防和抑制病毒传播的一种方法是接种疫苗。疫苗的作用是提供免疫力。库邦市的许多人不相信新冠肺炎疫苗的有效性,因此他们不想接种疫苗。本研究的目的是描述库邦市Oebobo区Liliba村公众对新冠肺炎疫苗有效性的信心水平。研究方法是定量的,采用描述性研究设计。人口居住在库邦市Oebobo区Liliba街道。样本为106人,他们是使用聚类简单随机抽样技术采集的。结果显示,公众对新冠肺炎疫苗易感性的信心水平为(89.6%)、疫苗有效性的严重性(90.6%)、接种疫苗的益处(54.7%)和感知障碍(88.7%),库邦市地势较高。
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引用次数: 0
The Relationship of Mother's Role in Stimulation with Motor Development in Toddler 母亲刺激角色与幼儿运动发展的关系
Pub Date : 2022-06-27 DOI: 10.31965/infokes.vol20.iss1.618
Suriani B, Nurfatimah Nurfatimah, Djuhadiah Saadong, Subriah Subriah, Kadar Ramadhan
Toddler period is an important phase in the growth and development of children. The role of parents, especially mothers, is needed to help children develop motor skills so that children's development can be maximized. The objective of this study is to analyze the mother's role in stimulating the child's motor development. The research method is cross sectional. The population in this study were mothers who had children aged 1-3 years in the work area of the Mangasa Primary Health Center, Makassar, amounting to 45 people. The sample in this study was 45 people, taken with a saturated sampling technique or the total population. The statistical test used the chi square test. The results presented that 95.7% of mothers who played a role in stimulating children's motor development had children whose development was appropriate. The results of the chi square test obtained p value <0.001. The conclusion is that there is a relationship between mother's role in stimulation and the motor development of toddler. It is expected that the Primary Health Center or midwives will provide training to mothers about providing developmental stimulation so that mothers can independently assess their child's development and pay attention to their child's development according to age.
幼儿期是儿童成长发育的重要阶段。父母,尤其是母亲,需要帮助孩子发展运动技能,这样孩子的发展才能最大化。本研究的目的是分析母亲在刺激儿童运动发育中的作用。研究方法是横断面的。本研究的对象是在望加锡Mangasa初级保健中心工作区域有1-3岁子女的母亲,共计45人。这项研究的样本是45人,采用饱和抽样技术或总人口。统计检验采用卡方检验。结果表明,在刺激儿童运动发育中起作用的母亲中,95.7%的母亲所生的孩子发育良好。卡方检验的结果得到p值<0.001。结论:母亲的刺激作用与幼儿运动发育之间存在一定的关系。预计初级保健中心或助产士将向母亲提供关于提供发育刺激的培训,以便母亲能够独立评估其子女的发育,并根据年龄关注其子女的发育。
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引用次数: 0
Sensory Evaluation and Nutritional Quality of Corn Tortilla Enriched with Moringa Seed Flour 辣木籽粉强化玉米粉的感官评价及营养品质
Pub Date : 2022-06-27 DOI: 10.31965/infokes.vol20.iss1.573
A. Nur, J. G. L. Sine, Maria Helena Dua Nita
One of the agricultural product processing industries currently being developed in East Nusa Tenggara is corn. Corn has a relatively high nutritional content, thus it possesses economic value for the community. One of the snack products from corn is tortilla. The tortillas can be modified with other food ingredients that contain good nutrition to increase its nutritional value. Moringa seeds contain carbohydrates, fats and proteins. Hence, moringa seeds can be an alternative food source of a new protein which is able to overcome protein deficiency, particularly in East Nusa Tenggara. The experiment was designed by Completely Randomized Design (CRD) with several formulas for substitution of corn flour with moringa seed flour, which were: P1 (100%: 0%), P2 (95%:5%), P3 (90%:10%), and P4 (85%:15%). An organoleptic test was administered to determine the panelists' preference for tortilla formulas and a proximate test to examine the nutritional value of tortillas. The results of the organoleptic test revealed that corn tortilla substituted with moringa seed flour up to 20% owned a significant effect on the color, aroma, taste and texture of the tortilla with a p-value <0.05. The proximate test results presented that tortillas with moringa seed flour substitution possessed a significant effect on protein, fat, carbohydrate, water, ash and fibre content of tortilla with a p-value <0.05.
东努沙登加拉目前正在发展的农产品加工业之一是玉米。玉米的营养含量较高,因此对社区具有经济价值。玉米饼是玉米制成的零食之一。玉米饼可以用含有良好营养的其他食品成分进行改良,以提高其营养价值。辣木种子含有碳水化合物、脂肪和蛋白质。因此,辣木种子可以作为一种新蛋白质的替代食物来源,这种蛋白质能够克服蛋白质缺乏症,特别是在东努沙登加拉。本实验采用完全随机设计(CRD)设计,用辣木籽粉代替玉米粉的几种配方为:P1(100%:0%)、P2(95%:5%)、P3(90%:10%)和P4(85%:15%)。进行了感官测试,以确定小组成员对玉米饼配方的偏好,并进行了接近测试,以检查玉米饼的营养价值。感官测试结果表明,用高达20%的辣木籽粉代替玉米饼对玉米饼的色、香、味和质地有显著影响,p值<0.05。试验结果表明,辣木籽粉替代玉米饼对玉米饼的蛋白质、脂肪、碳水化合物、水分、灰分和纤维含量有显著影响,p值<0.05。
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引用次数: 0
Relationship between Procalcitonin Levels (PCT) and Disease Severity in Hospitalized Patients Confirmed Positive for COVID-19 新冠肺炎确诊阳性住院患者降钙素原水平(PCT)与疾病严重程度的关系
Pub Date : 2022-06-27 DOI: 10.31965/infokes.vol20.iss1.638
Rizana Fajrunni’mah, F. Rada, R. M. Widhyasih
Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This disease attacks the respiratory tract and spreads rapidly almost throughout the world, hence, WHO has declared COVID-19 as a global pandemic. The presence of inflammation and bacterial co-infection in COVID-19 hospitalized patients can increase procalcitonin (PCT) levels as a biomarker of inflammation. Elevated PCT levels are also associated with disease severity. The objective of this study is to determine the relationship between PCT levels and disease severity in hospitalized patients who are confirmed positive for COVID-19. This research method is analytic observational with cross sectional design. The sample is in the form of medical record data for 180 COVID-19 patients who are hospitalized at Bhayangkara Tk. I Raden Said Sukanto Hospital, Jakarta for the period July-December 2020. The relationship between PCT levels and disease severity was statistically analyzed using the Chi Square test. The results of this study were 109 (60.6%) men and 71 (39.4%) women with the highest age group being 46-59 years. The average PCT level was 10.38 ng/mL with the lowest level of 0.01 ng/mL and the highest level of 282.00 ng/mL. PCT levels <0.5 ng/mL were discovered in 111 patients (61.7%) and PCT levels 0.5 ng/mL in 69 patients (38.3%). The severity of disease in mild-moderate illness was 87 patients (48.4%), severe was 35 patients (19.4%), and critical was 58 patients (32.2%). The Chi Square test showed that there was a relationship between PCT levels and disease severity in COVID-19 patients (p = 0.000). The higher the PCT level, the higher the severity of the disease, thus, PCT can be used as an indicator to see the severity of the disease.
2019冠状病毒病(新冠肺炎)是由严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引起的传染病。这种疾病侵袭呼吸道,几乎在全世界迅速传播,因此,世界卫生组织宣布新冠肺炎为全球大流行。新冠肺炎住院患者中炎症和细菌共同感染的存在可以增加降钙素原(PCT)水平,作为炎症的生物标志物。PCT水平升高也与疾病的严重程度有关。本研究的目的是确定新冠肺炎确诊阳性住院患者的PCT水平与疾病严重程度之间的关系。这种研究方法是采用截面设计的分析观测方法。样本采用2020年7月至12月期间在雅加达Bhayangkara Tk.I Raden Said Sukanto医院住院的180名新冠肺炎患者的病历数据形式。PCT水平与疾病严重程度之间的关系使用卡方检验进行统计分析。这项研究的结果是109名(60.6%)男性和71名(39.4%)女性,最高年龄组为46-59岁。平均PCT水平为10.38 ng/mL,最低水平为0.01 ng/mL,最高水平为282.00 ng/mL。111例(61.7%)PCT水平<0.5 ng/mL,69例(38.3%)PCT水平>0.5 ng/mL,其中危重58例(32.2%)。卡方检验显示,新冠肺炎患者的PCT水平与疾病严重程度之间存在相关性(p=0.000)。PCT水平越高,疾病严重程度越高,因此PCT可以作为衡量疾病严重程度的指标。
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引用次数: 0
Determinants of Contraceptive Use at The First Sexual Intercourse among Unmarried Adolescents in Indonesia: 2017 IDHS Analysis 印度尼西亚未婚青少年第一次性交时避孕药具使用的决定因素:2017年IDHS分析
Pub Date : 2022-06-27 DOI: 10.31965/infokes.vol20.iss1.684
Restya Sri Sugiarti, H. Helda, Kholisotul Hikmah
Adolescents confront boundaries in obtaining contraception counting prohibitive policies and adolescents possess failure to obtain contraceptives since of information, transportation, and monetary limitations. The objective of this study is to assign the variables which impact on the use of contraception for the first sexual intercourse among unmarried adolescents. Quantitative research employing cross sectional analysis was implemented in this study, by processing 2017 Indonesian Health Demographic Survey (IDHS) data. Cox regression was utilized to examine the association between sociodemographic, peer and social influences, contraceptive knowledge and contraceptive use. The study populace encompassed 705 single young people; 15 to 24 years old. The study resulted that contraceptive use at the primary sexual intercourse by single young people in Indonesia was approximately 50.35%. After bivariate analysis was applied, it was revealed that there is a significant relationship between education with the contraceptive use at the first sexual intercourse among unmarried adolescents in Indonesia (p-value = 0.049). In the final model, we discovered that the level of education and contraceptive use was statistically significant, and the contraceptive use was higher in adolescents with high education than adolescents with middle and primary education (PR 1.51, 95% CI 1.09 – 2.07, p = 0.012). Therefore, this finding provides information that education is a prominent variable for understanding contraceptive use in adolescents.
青少年在获得避孕药具方面面临着限制性政策,由于信息、交通和金钱的限制,青少年无法获得避孕药器。本研究的目的是分配影响未婚青少年首次性交避孕的变量。本研究通过处理2017年印尼健康人口调查(IDHS)数据,采用横断面分析进行定量研究。Cox回归用于检验社会人口统计学、同伴和社会影响、避孕知识和避孕药具使用之间的关系。研究人群包括705名单身青年;15至24岁。研究结果表明,印尼单身年轻人在初次性交时使用避孕药具的比例约为50.35%。应用双变量分析后发现,印尼未婚青少年的教育程度与初次性交时的避孕药具使用之间存在显著关系(p值=0.049)。在最终模型中,我们发现,受教育程度和避孕药具的使用具有统计学意义,受过高等教育的青少年的避孕药具使用率高于受过中等和初等教育的青少年(PR 1.51,95%CI 1.09-2.07,p=0.012)。
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引用次数: 0
Measuring the Antioxidant Effect of Limnocharis Flava on Malondialdehyde Activities in Livers of Alloxan-induced Diabetic Rats 亚麻对四氧嘧啶糖尿病大鼠肝脏丙二醛活性的抗氧化作用
Pub Date : 2021-12-31 DOI: 10.31965/infokes.vol19.iss2.534
Y. Serang, Virda Laili
Antioxidants are substances counteracting the effects of free radicals. Antioxidants are formed in several forms, encompassing vitamins, minerals, and phytochemicals. Genjer or yellow velvet leaves (Limnocharis Flava) is an aquatic plant potentially beneficial alternative to natural antioxidants. This study aims to measure the antioxidant effect from the yellow velvetleaf ethanol extract on malondialdehyde (MDA) activities in livers of diabetic rats (Rattus novergicus) induced by alloxan in three different doses. The tested animals were randomly divided into five groups comprising six white rats previously induced with alloxan by intra-peritoneal injection. Group 1 was the negative control provided 0.5% CMC Na while group 2 was a positive control administered 0.45 mg glibenclamide. On the other hand, groups 3, 4, and 5 were the experimental groups that provided the extract of yellow velvetleaf as many as 32.5 mg/kg body weight (BW) ethanol, 65 mg/kg BW ethanol extract, and 130 mg/kg BW, respectively. Furthermore, the extracts were administered once on the 7th, 14th, and 21st days; the parameters observed were MDA activities in the rats’ livers. The Thiobarbituric Acid Reactive Substances (TBARs) method was then employed to investigate these actions. The one-way ANOVA was administered to examine the acquired data from the examination, followed by a post hoc test. The average points of the MDA level from group 1 to group 5 were 10.78 0.33, 3.71 + 0.19, 7.25 + 0.26, 5.76 + 0.25, and 4.01 + 0.22, correspondingly, according to the results. The one-way ANOVA test revealed that MDA levels in each test group were significantly different (p 0.05). Based on these findings, it may be concluded that feeding ethanol extract from yellow velvet leaves to diabetic rats reduces MDA levels in their livers, therefore preserving cells from harm.
抗氧化剂是对抗自由基作用的物质。抗氧化剂有多种形式,包括维生素、矿物质和植物化学物质。黄绒叶(Limnocharis Flava)是一种水生植物,可能是天然抗氧化剂的有益替代品。本研究旨在测定黄丝绒叶乙醇提取物对三种不同剂量四氧嘧啶诱导的糖尿病大鼠(Rattus novergicus)肝脏丙二醛(MDA)活性的抗氧化作用。试验动物被随机分为五组,包括六只先前通过腹膜内注射四氧嘧啶诱导的大白鼠。第1组为阴性对照,提供0.5%CMC Na,而第2组为阳性对照,给予0.45 mg格列本脲。另一方面,第3组、第4组和第5组是分别提供高达32.5mg/kg体重(BW)乙醇、65mg/kg体重乙醇提取物和130mg/kg体重的黄绒叶提取物的实验组。此外,提取物在第7天、第14天和第21天给药一次;观察到的参数是大鼠肝脏中MDA的活性。然后采用硫代巴比妥酸反应物质(TBARs)方法来研究这些作用。单因素方差分析用于检查从检查中获得的数据,然后进行事后检验。结果显示,第1组至第5组MDA水平的平均值分别为10.78 0.33、3.71+0.19、7.25+0.26、5.76+0.25和4.01+0.22。单因素方差分析显示,各试验组的MDA水平存在显著差异(p 0.05)。基于这些发现,可以得出结论,给糖尿病大鼠喂食黄丝绒叶乙醇提取物可以降低其肝脏中的MDA水平,从而保护细胞免受伤害。
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引用次数: 1
Hemodialysis Duration with Levels of Hemoglobin, Hematocrit, Serum Iron and Total Iron Binding Capacity on Chronic Kidney Disease 慢性肾脏病血液透析持续时间与血红蛋白、红细胞压积、血清铁和总铁结合能力的关系
Pub Date : 2021-12-31 DOI: 10.31965/infokes.vol19.iss2.523
Supriati Wila Djami, Marni Tangkelangi
The correlation of the length of time undergoing hemodialysis with the levels of hemoglobin, hematocrit, serum iron and total iron binding capacity in patients with chronic kidney disease at RSUD Prof. Dr. W. Z. Johannes Kupang. People with chronic kidney disease who are performing Hemodialysis suffer from anemia. Blood loss during the hemodialysis process is affected by frequent blood sampling for laboratory tests. To diagnose the occurrence of iron deficiency, anemia laboratory tests such as complete blood, serum iron (SI), TIBC, transferrin saturation, and serum ferritin can be conducted. The objective of this study is to determine the correlation between the length of undergoing Hemodialysis with the levels of Hemoglobin, Hematocrit, Serum Iron, and Total Iron Binding Capacity (TIBC) in patients with chronic kidney disease in RSUD Prof. Dr.W. Z Johannes Kupang. This study employed an anon-reactive research design or unobtrusive research based on secondary data derived from medical record records at RSUD Prof. Dr.W. Johannes in August - September 2019 on 92 hemodialysis patients who met the inclusion criteria. The collected data were calculated with the SPSS application, while the correlation analysis between variables was performed by administering a linear regression analysis test. Ninety-two (92) respondents were obtained by employing the purposive sampling technique. The majority of patients with chronic kidney disease undergoing Hemodialysis were men (57.6%) with ages 39 - 59 years (63.0%), and the majority of patients undergoing Hemodialysis in patients with chronic kidney failure (CKD) were <12 months (41.3%). It was discovered that there was no relationship between the length of Hemodialysis with hemoglobin, hematocrit, serum iron, and total iron-binding capacity levels in patients with chronic kidney disease (CKD).
RSUD教授W.Z.Johannes Kupang博士对慢性肾脏病患者进行血液透析的时间长度与血红蛋白、红细胞压积、血清铁和总铁结合能力水平的相关性进行了研究。正在进行血液透析的慢性肾脏病患者患有贫血。血液透析过程中的失血会受到实验室检查频繁抽血的影响。为了诊断缺铁的发生,可以进行贫血实验室测试,如全血、血清铁(SI)、TIBC、转铁蛋白饱和度和血清铁蛋白。本研究的目的是确定RSUD教授Johannes Kupang博士的慢性肾脏疾病患者接受血液透析的时间与血红蛋白、红细胞压积、血清铁和总铁结合能力(TIBC)水平之间的相关性。这项研究采用了一种非反应性研究设计或不引人注目的研究,基于2019年8月至9月RSUD教授Johannes博士对92名符合纳入标准的血液透析患者的病历记录中的二次数据。收集的数据使用SPSS应用程序进行计算,而变量之间的相关性分析则通过线性回归分析测试进行。九十二(92)名受访者是通过采用目的性抽样技术获得的。大多数接受血液透析的慢性肾脏病患者是年龄在39-59岁之间的男性(57.6%)(63.0%),大多数慢性肾功能衰竭(CKD)患者接受血液透析时间<12个月(41.3%),以及慢性肾脏疾病(CKD)患者的总铁结合能力水平。
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引用次数: 0
Exercise Program: Tai Chi and Cognitive Stimulation to Improve Health Status of Elderly in Nursing Homes 运动项目:太极拳和认知刺激改善养老院老年人健康状况
Pub Date : 2021-12-31 DOI: 10.31965/infokes.vol19.iss2.585
Ni Made Riasmini, Eska Riyanti, I. Suardana, I. K. Gama, H. Khatimah
The structure of the aging population reflects the higher average life expectancy, which possesses an impact on the emergence of degenerative non-communicable diseases. Promotive effort through an exercise program (tai-chi exercise and cognitive stimulation) is required for the elderly to enhance their physical and mental health. This study aims to determine an overview of the exercise program's effectiveness on the health status of the elderly in nursing homes. The research method administered Quasi experiment with a control group design. The sample was the elderly who live in nursing homes. This study employed simple random sampling with a total sample of 116 people in 2 provinces: DKI Jakarta and South Sumatra Province. The statistical test utilized a t-test and multiple linear regression test. The results revealed that there was a difference in the average value of the health status of the elderly before and after the exercise programs in the intervention group (p-value = 0.001), there was a difference in the average value of the health status of the elderly between the intervention group and the control group after the exercise intervention program (p-value = 0.001), there was a relationship between the length of stay in the orphanage on the health status of the elderly. Recommendation: the resulting exercise program can be employed as complementary therapies replicated more extensively in various health care settings.
人口老龄化的结构反映了较高的平均预期寿命,这对退行性非传染性疾病的出现产生了影响。需要通过锻炼计划(太极运动和认知刺激)来促进老年人的身心健康。本研究旨在确定锻炼计划对养老院老年人健康状况的影响。研究方法采用对照组设计进行准实验。样本是住在疗养院的老年人。这项研究采用了简单的随机抽样,共有两个省的116人参加:DKI雅加达省和南苏门答腊省。统计检验采用了t检验和多元线性回归检验。结果显示,干预组的老年人在运动项目前后的健康状况平均值存在差异(p值=0.001),干预组与对照组在运动干预项目后的健康状况的平均值存在差别(p值p=0.001),孤儿院的住院时间与老年人的健康状况之间存在关系。建议:由此产生的锻炼计划可以作为补充疗法,在各种医疗保健环境中更广泛地复制。
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引用次数: 1
The Effectiveness of Pineapple Extract (Ananas Comosus) and Kesum Leaves (Polygonus Minus) on the Quality of Coconut Oil (Coconus Nucifera) 菠萝提取物(Ananas Comosus)和决明叶(Polygonus Minus)对椰子油质量的影响
Pub Date : 2021-12-31 DOI: 10.31965/infokes.vol19.iss2.519
Hendra Budi Sungkawa, Wahdaniaht Wahdaniah, Herlinda Djohan
The processed oil from the coconut plant is generally understood as coconut oil. A method is required to produce a product with a higher oil extraction rate and is able to reduce the water content and free fatty acids in the coconut oil production. It is also necessary to add substances that can delay or prevent fat oxidation reactions by generating substances in the form of antioxidants. The method that can be implemented is the enzymatic method employing the bromelain enzyme in a pineapple with the addition of an antioxidants substance from the kesum  leaf. The objective of this research is to describe the quality of coconut oil after the addition of pineapple (ananas comosus) and kesum leaves (polygonus minus) extracts. The parameters for describing the quality of the oil are the organoleptic test, the degree of acidity, the oil extract rate, the peroxide number, the saponification number, and the acid number. This research is a quasi-experiment. The samples in this research were coconut oil without the addition of pineapple fruit extract, coconut oil with the addition of pineapple fruit extract without the addition of kesum leaves, and coconut oil with the addition of pineapple fruit extract and kesum leaves as much as 20gr, 30gr and 40gr. Based on the statistical results of the linear regression test, it was discovered that p-value = 0.000 <0.05, so it was concluded that there was an effect of the addition of pineapple fruit and leaves of kesum on acid number content with an effect of 76.4% on the acid number, 71.4% on the peroxide number, and 81.5% to the saponification number. It is recommended to test the water content, free fatty acids, and iodine number.
从椰子植物中提炼出来的油通常被理解为椰子油。需要一种能够生产出更高提取率的产品并能够降低椰子油生产中的水分和游离脂肪酸的方法。还需要添加可以通过产生抗氧化剂形式的物质来延缓或防止脂肪氧化反应的物质。所述可实施的方法是利用菠萝中的菠萝蛋白酶酶加上从菠萝叶中提取的抗氧化剂物质的酶促方法。本研究的目的是描述加入菠萝(ananas comosus)和kesum叶(polygonus minus)提取物后的椰子油的质量。描述油质量的参数是感官试验、酸度、油提取率、过氧化值、皂化值和酸值。这项研究是一项准实验。本研究样品为不添加菠萝果提取物的椰子油、添加菠萝果提取物而不添加香蒲叶的椰子油、添加菠萝果提取物和香蒲叶分别为20gr、30gr和40gr的椰子油。根据线性回归检验的统计结果,发现p值= 0.000 <0.05,因此可以得出菠萝果和kesum叶的添加对酸值含量有影响,其中对酸值的影响为76.4%,对过氧化值的影响为71.4%,对皂化值的影响为81.5%。建议检测水分含量、游离脂肪酸和碘值。
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引用次数: 0
Survival of Patients on Maintenance Hemodialysis Base on Comorbidity of Cardiovascular Disease in Persahabatan Central General Hospital 2015-2019 2015-2019年柏沙巴坦中心总医院基于心血管疾病合并症的维持性血液透析患者生存率分析
Pub Date : 2021-12-31 DOI: 10.31965/infokes.vol19.iss2.547
Mila Fitriaty, N. Adnan, M. Syafiq
Chronic kidney disease is the progressive loss of kidney function over months or years. The significant increase in new cases of chronic kidney disease is in line with the increasing number of patients undergoing hemodialysis as kidney replacement therapy in an effort to survive. Comorbid cardiovascular disease is a major risk factor for morbidity and mortality with chronic kidney disease. The study was conducted to determine the survival of hemodialysis patients in the group with comorbid cardiovascular disease and the group without comorbid cardiovascular disease. This study used a retrospective cohort design. The location of this study was conducted at Persahabatan Central Public Hospital, DKI Jakarta, and used secondary data from the hospital information system data from 2015 to 2019. The variables significantly related to the survival of patients undergoing hemodialysis with comorbid cardiovascular disease were age, complications of anemia, diabetes mellitus, and hypertension. The age variable has a p-value of 0.029 with an HR of 1.54 (95% CI OR 1.043-2.262). The anemia variable has a p-value of 0.013 with an HR of 1.60 (95% CI 1.117-2.515). The diabetes mellitus variable has a p-value of 0.000 with HR2.71 (95% CI 1.780-4.11). The hypertension variable has a p-value of 0.004 with HR1.79 (95% CI 1.208-2.646). In conclusion, patients undergoing hemodialysis with comorbid cardiovascular disease have a risk of death of 0.76 times compared to patients undergoing hemodialysis with the comorbid non-cardiovascular disease. This study's internal validity was not good due to selection bias and non-differential misclassification information bias. Thus, the results of this study cannot be generalized.
慢性肾脏疾病是指几个月或几年肾脏功能的逐渐丧失。慢性肾脏疾病新病例的显著增加与接受血液透析作为肾脏替代疗法以生存的患者数量的增加是一致的。并发心血管疾病是慢性肾脏疾病发病率和死亡率的主要危险因素。本研究旨在确定合并心血管疾病组和未合并心血管疾病组血液透析患者的生存。本研究采用回顾性队列设计。本研究的地点在雅加达DKI Persahabatan中央公立医院进行,并使用了2015年至2019年医院信息系统数据中的二次数据。年龄、贫血并发症、糖尿病和高血压与合并心血管疾病的血液透析患者的生存率有显著关系。年龄变量的p值为0.029,HR为1.54 (95% CI OR 1.043-2.262)。贫血变量的p值为0.013,HR为1.60 (95% CI 1.117-2.515)。糖尿病变量的p值为0.000,HR2.71 (95% CI 1.780-4.11)。高血压变量的p值为0.004,HR1.79 (95% CI 1.208-2.646)。综上所述,合并心血管疾病的血液透析患者的死亡风险是合并非心血管疾病的血液透析患者的0.76倍。由于选择偏倚和非差异误分类信息偏倚,本研究的内部效度不佳。因此,本研究的结果不能一概而论。
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