Pub Date : 2021-12-31DOI: 10.31965/infokes.vol19.iss2.545
Edy Suwandi, Ari Nuswantoro, S. Sugito, Desi Wahyumarniasari, Muhammad Reza Setiawan, Dinasti Aprillia, Devi Nurfitri Bintang
Chocolate has long been understood to provide positive emotions and a good mood if consumed in moderation. Chocolate contains prebiotics naturally from its constituent ingredients produced during the production process. Prebiotics, frequently oligosaccharides, are substances which cannot be metabolized by the human digestive system but can be employed by a group of bacteria in the gut, understood as probiotics. The positive relationship among them provides benefits for the host in eliminating pathogens. One of the well-known pathogens which frequently cause infection either in the community or in hospitals is methicillin-resistant Staphylococcus aureus (MRSA). Since it was first identified in 1960, MRSA has caused health problems until today. Research conducted on two groups of Rattus norvegicus infected with MRSA and then fed chocolate revealed a decrease in the average number of bacterial colonies on the skin compared to the control group. In the group fed chocolate at a dose of 50 mg/day, the bacterial colonies decreased to 1.28 x 108 CFU/cm2 in 7 days, lower than in the control group (1.46 x 108 CFU/cm2) at the same time. While those fed 75 mg/day chocolate decreased to 2.70 x 107 CFU/cm2 and the three groups were significantly different (0.000<0.05). Prebiotics fermented by probiotics release short-chain fatty acids (SCFA), which compete with the pathogens for attaching to the epithelial wall so that pathogens lose space and nutrients to survive. However, the adverse effect of chocolate may occur because it contains sugar which is a nutrient for bacteria, but if the balance of normal flora and adequate intake of prebiotics are administered, the pathogen could be eliminated.
长期以来，人们一直认为，如果适量食用，巧克力可以提供积极的情绪和良好的心情。巧克力含有益生元，这些益生元是在生产过程中产生的。益生素，通常是低聚糖，是一种不能被人类消化系统代谢的物质，但可以被肠道中的一组细菌利用，被称为益生菌。它们之间的积极关系为宿主消灭病原体提供了好处。在社区或医院中经常引起感染的已知病原体之一是耐甲氧西林金黄色葡萄球菌（MRSA）。自1960年首次被发现以来，MRSA一直造成健康问题，直到今天。对感染MRSA并喂食巧克力的两组褐家鼠进行的研究表明，与对照组相比，皮肤上的平均菌落数量有所减少。在喂食50 mg/天剂量巧克力的组中，菌落在7天内降至1.28 x 108 CFU/cm2，低于同期对照组（1.46 x 108 CFU/cm2）。而喂食75 mg/天巧克力的人减少到2.70 x 107 CFU/cm2，三组之间存在显著差异（0.000<0.05）。益生菌发酵的益生素释放出短链脂肪酸（SCFA），与病原体竞争附着在上皮壁上，使病原体失去生存的空间和营养。然而，巧克力的不良影响可能会发生，因为它含有糖，而糖是细菌的营养素，但如果保持正常菌群的平衡并摄入足够的益生元，病原体可能会被消灭。
{"title":"The Effectiveness of Chocolate in Reducing the Number of Methicillin-Resistant Staphylococcus aureus Colonies in Rattus norvegicus","authors":"Edy Suwandi, Ari Nuswantoro, S. Sugito, Desi Wahyumarniasari, Muhammad Reza Setiawan, Dinasti Aprillia, Devi Nurfitri Bintang","doi":"10.31965/infokes.vol19.iss2.545","DOIUrl":"https://doi.org/10.31965/infokes.vol19.iss2.545","url":null,"abstract":"Chocolate has long been understood to provide positive emotions and a good mood if consumed in moderation. Chocolate contains prebiotics naturally from its constituent ingredients produced during the production process. Prebiotics, frequently oligosaccharides, are substances which cannot be metabolized by the human digestive system but can be employed by a group of bacteria in the gut, understood as probiotics. The positive relationship among them provides benefits for the host in eliminating pathogens. One of the well-known pathogens which frequently cause infection either in the community or in hospitals is methicillin-resistant Staphylococcus aureus (MRSA). Since it was first identified in 1960, MRSA has caused health problems until today. Research conducted on two groups of Rattus norvegicus infected with MRSA and then fed chocolate revealed a decrease in the average number of bacterial colonies on the skin compared to the control group. In the group fed chocolate at a dose of 50 mg/day, the bacterial colonies decreased to 1.28 x 108 CFU/cm2 in 7 days, lower than in the control group (1.46 x 108 CFU/cm2) at the same time. While those fed 75 mg/day chocolate decreased to 2.70 x 107 CFU/cm2 and the three groups were significantly different (0.000<0.05). Prebiotics fermented by probiotics release short-chain fatty acids (SCFA), which compete with the pathogens for attaching to the epithelial wall so that pathogens lose space and nutrients to survive. However, the adverse effect of chocolate may occur because it contains sugar which is a nutrient for bacteria, but if the balance of normal flora and adequate intake of prebiotics are administered, the pathogen could be eliminated.","PeriodicalId":34064,"journal":{"name":"Jurnal Info Kesehatan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44945133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Senggani fruit (Melastoma Malabathricum L.) contains anthocyanin that functioning as an antioxidant. Anthocyanin are tremendously sensitive to thermal processes which trigger phytochemical or photo-oxidation reactions that can open anthocyanin rings. The objective of this study is to identify the effect of the simplicia drying method on the antioxidant activity of Senggani fruit extract. Senggani fruit extract was prepared by obtaining samples of ripe fruit, dry sorting, washing, wet sorting, and drying using two methods; sunlight and oven at 70oC. After the simplicia was dry, it was blended and sifted until smooth. The fine simplicia was macerated with 96% ethanol and evaporated to gain a crude extract. The crude extract was assessed with reagents for phytochemical screening. Furthermore, the crude extract was examined for antioxidant activity by the DPPH method. This study implies that the simplicia and crude extract of Senggani fruit from drying in sunlight and oven possess different organoleptic properties such as color, smell, and taste. In phytochemical testing with reagents, it was discovered that anthocyanin compounds were unveiled in drying utilizing sunlight while employing an oven at 70oC; no anthocyanins were found. The antioxidant testing of Senggani fruit extract revealed that the drying method employing sunlight had an IC50 value of 18.8 g/mL while the oven temperature of 70oC owned an IC50 value of 28.3 g/mL. Based on the study results, it can be identified that the simplicia drying method affects the antioxidant activity of the Senggani fruit extract. The drying method in the sun produces extracts with greater antioxidant activity while drying in an oven at 70oC results in a degradation process of anthocyanin compounds, thereby decreasing the antioxidant activity of the Senggani fruit extract.
{"title":"The Effect of Simplisia Drying Method on Antioxidant Activity of Senggani Fruit Extract (Melastoma Malabathricum L.) by DPPH (2,2-diphenyl-1-picrylhydrazyl)","authors":"Shesanthi Citrariana, Risqika Yuliatantri Paramawidhita, Melliani Melliani","doi":"10.31965/infokes.vol19.iss2.539","DOIUrl":"https://doi.org/10.31965/infokes.vol19.iss2.539","url":null,"abstract":"Senggani fruit (Melastoma Malabathricum L.) contains anthocyanin that functioning as an antioxidant. Anthocyanin are tremendously sensitive to thermal processes which trigger phytochemical or photo-oxidation reactions that can open anthocyanin rings. The objective of this study is to identify the effect of the simplicia drying method on the antioxidant activity of Senggani fruit extract. Senggani fruit extract was prepared by obtaining samples of ripe fruit, dry sorting, washing, wet sorting, and drying using two methods; sunlight and oven at 70oC. After the simplicia was dry, it was blended and sifted until smooth. The fine simplicia was macerated with 96% ethanol and evaporated to gain a crude extract. The crude extract was assessed with reagents for phytochemical screening. Furthermore, the crude extract was examined for antioxidant activity by the DPPH method. This study implies that the simplicia and crude extract of Senggani fruit from drying in sunlight and oven possess different organoleptic properties such as color, smell, and taste. In phytochemical testing with reagents, it was discovered that anthocyanin compounds were unveiled in drying utilizing sunlight while employing an oven at 70oC; no anthocyanins were found. The antioxidant testing of Senggani fruit extract revealed that the drying method employing sunlight had an IC50 value of 18.8 g/mL while the oven temperature of 70oC owned an IC50 value of 28.3 g/mL. Based on the study results, it can be identified that the simplicia drying method affects the antioxidant activity of the Senggani fruit extract. The drying method in the sun produces extracts with greater antioxidant activity while drying in an oven at 70oC results in a degradation process of anthocyanin compounds, thereby decreasing the antioxidant activity of the Senggani fruit extract. \u0000 ","PeriodicalId":34064,"journal":{"name":"Jurnal Info Kesehatan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43270123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-31DOI: 10.31965/infokes.vol19.iss2.525
D. Pratiwi, Djauhar Ismail, Mufdlilah Mufdlilah, Panyada Cholsakhon
The number of low-birth-weight babies (LBW) who returned to the hospital after returning home had increased from 2015 to 2016. The results of the interview revealed that mothers who had LBW did not thoroughly understand providing care for LBW after returning from the hospital. This study aims to determine the effect of health education on a mother's knowledge, attitude and behaviour in providing care to LBW. This study is quasi-experimental with a pre-posttest approach non-equivalent to the control group, with 66 respondents fulfilling the inclusion criteria. The inclusion criteria in this study were post-partum mothers on the second day who had babies with a birth weight of 1500 grams-2499 grams and were willing to be respondents. The sampling technique was purposive sampling. The statistical test employed independent t-test, paired t-test, and chi-square. Knowledge scores before and after treatment were significantly different in the intervention group and control group, with a p-value in the intervention group 0.00, while the knowledge and attitude scores in the control group were 0.00 and the behavioural scores were 0.11. There was a significant difference in the increase in knowledge, attitudes and behaviour scores in both groups. The p-value of knowledge and attitudes is 0.00, and the p-value of behaviour is 0.01. Hence, there is an increase in mothers' knowledge, attitudes, and behaviour after being provided with health education using a booklet.
{"title":"The Effect of Health Education on Mother's Knowledge Attitudes and Behavior in Giving Care to Low Birth Weight Babies","authors":"D. Pratiwi, Djauhar Ismail, Mufdlilah Mufdlilah, Panyada Cholsakhon","doi":"10.31965/infokes.vol19.iss2.525","DOIUrl":"https://doi.org/10.31965/infokes.vol19.iss2.525","url":null,"abstract":"The number of low-birth-weight babies (LBW) who returned to the hospital after returning home had increased from 2015 to 2016. The results of the interview revealed that mothers who had LBW did not thoroughly understand providing care for LBW after returning from the hospital. This study aims to determine the effect of health education on a mother's knowledge, attitude and behaviour in providing care to LBW. This study is quasi-experimental with a pre-posttest approach non-equivalent to the control group, with 66 respondents fulfilling the inclusion criteria. The inclusion criteria in this study were post-partum mothers on the second day who had babies with a birth weight of 1500 grams-2499 grams and were willing to be respondents. The sampling technique was purposive sampling. The statistical test employed independent t-test, paired t-test, and chi-square. Knowledge scores before and after treatment were significantly different in the intervention group and control group, with a p-value in the intervention group 0.00, while the knowledge and attitude scores in the control group were 0.00 and the behavioural scores were 0.11. There was a significant difference in the increase in knowledge, attitudes and behaviour scores in both groups. The p-value of knowledge and attitudes is 0.00, and the p-value of behaviour is 0.01. Hence, there is an increase in mothers' knowledge, attitudes, and behaviour after being provided with health education using a booklet.","PeriodicalId":34064,"journal":{"name":"Jurnal Info Kesehatan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46274919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-31DOI: 10.31965/infokes.vol19.iss2.518
Diah Ratnawati, Nourmayansa Vidya Anggraini
Adolescents are physically and psychologically vulnerable to the transmission of HIV/AIDS, so that they become the focus of the population for disease prevention programs. This study aims to determine the effect of perceptions of social support and family health tasks on HIV/AIDS prevention behavior in adolescents in Baros Village, Serang, Banten. This study employed a quantitative research method with a cross-sectional design. The number of samples was 345 adolescents who were at risk of HIV/AIDS in Baros Village, Serang, Banten. Sampling from each class administering stratified sampling method. Researchers reproduced research questionnaires with an offline system which had previously been examined for the validity and reliability of a number of samples that have been calculated. Furthermore, for research questionnaires with an online system, distribution is conducted via a link from the google form. The chi-square test was administered to examine HIV/AIDS prevention behavior variables. A logistic regression test was used to see the most influential factors on HIV/AIDS prevention behavior. The results revealed a relationship between gender and family health tasks in recognizing HIV/AIDS prevention behavior problems in adolescents in Baros Village, Serang, Banten, with a p-value <0.05. The factor that most influenced HIV/AIDS prevention behavior was the family health task in recognizing problems with a p-value of 0.007 <0.05 with the largest OR value obtained, which is 1.978. Therefore, families should improve their ability to conduct health tasks in communicating and directing adolescents in HIV/AIDS prevention behavior.
{"title":"The Influence of Perceptions of Social Support and Family Health Tasks on HIV/AIDS Prevention Behavior in Adolescents","authors":"Diah Ratnawati, Nourmayansa Vidya Anggraini","doi":"10.31965/infokes.vol19.iss2.518","DOIUrl":"https://doi.org/10.31965/infokes.vol19.iss2.518","url":null,"abstract":"Adolescents are physically and psychologically vulnerable to the transmission of HIV/AIDS, so that they become the focus of the population for disease prevention programs. This study aims to determine the effect of perceptions of social support and family health tasks on HIV/AIDS prevention behavior in adolescents in Baros Village, Serang, Banten. This study employed a quantitative research method with a cross-sectional design. The number of samples was 345 adolescents who were at risk of HIV/AIDS in Baros Village, Serang, Banten. Sampling from each class administering stratified sampling method. Researchers reproduced research questionnaires with an offline system which had previously been examined for the validity and reliability of a number of samples that have been calculated. Furthermore, for research questionnaires with an online system, distribution is conducted via a link from the google form. The chi-square test was administered to examine HIV/AIDS prevention behavior variables. A logistic regression test was used to see the most influential factors on HIV/AIDS prevention behavior. The results revealed a relationship between gender and family health tasks in recognizing HIV/AIDS prevention behavior problems in adolescents in Baros Village, Serang, Banten, with a p-value <0.05. The factor that most influenced HIV/AIDS prevention behavior was the family health task in recognizing problems with a p-value of 0.007 <0.05 with the largest OR value obtained, which is 1.978. Therefore, families should improve their ability to conduct health tasks in communicating and directing adolescents in HIV/AIDS prevention behavior.","PeriodicalId":34064,"journal":{"name":"Jurnal Info Kesehatan","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42311632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-31DOI: 10.31965/infokes.vol19.iss2.558
Avicena Sakufa Marsanti, Hanifah Ardiani
Tuberculosis (TB) is an infectious disease caused by Mycobacterium Tuberculosis Bacillus. The disease spreads in the air when people contract TB bacteria, such as coughing or sneezing. The lack of ability to anticipate the incidence of Acid Resistant Bacteria Positive Pulmonary TB in Madiun City is affected by the time and number of events that have not been appropriately foreseen. There is no map of regional vulnerability based on the time of occurrence. Hence, the incidence of Acid Resistant Bacteria Positive Pulmonary TB in Madiun city increases, determined by the total number of cases in 6 health centers, seven hospitals, and one prison. In 2015, there were 174 cases, then in 2019, 706 cases. The objective of this study is to predict the number of Acid Resistant Bacteria Positive Pulmonary TB suffering in 2021-2025 based on gender, health centers, and prisons in Madiun City and the overall incidence of cases in 2015-2019 is then foreseen in 2021 to 2025. This type of research is descriptive study research by employing Eviews with the ARIMA method. The population and samples in the study were all data of Acid Resistant Bacteria Positive Pulmonary TB case encompassing the sex of patients during 2015-2019 in Madiun City. The study aimed to predict the incidence of Acid Resistant Bacteria Positive Pulmonary TB in 2021-2025. The results of this study revealed the projection of Acid Resistant Bacteria Positive Pulmonary TB cases based on gender, health centers, hospitals, and prisons in Madiun City from 2020-2025, which experienced an increasing trend with the number of 933, 992, 1063, 1120, 1190 incidences respectively. This study is recommended for relevant agencies or health services to perform preventive efforts by involving trained policymakers and Health Cadis, particularly in preventing TB disease and reducing the high rate of predicting positive pulmonary TB smear incidences in the future.
{"title":"The Prediction Number of Smear Acid Resistant Bacteria on Positive Pulmonary Tuberculosis Infection Disease at Madiun City in 2021 to 2025","authors":"Avicena Sakufa Marsanti, Hanifah Ardiani","doi":"10.31965/infokes.vol19.iss2.558","DOIUrl":"https://doi.org/10.31965/infokes.vol19.iss2.558","url":null,"abstract":"Tuberculosis (TB) is an infectious disease caused by Mycobacterium Tuberculosis Bacillus. The disease spreads in the air when people contract TB bacteria, such as coughing or sneezing. The lack of ability to anticipate the incidence of Acid Resistant Bacteria Positive Pulmonary TB in Madiun City is affected by the time and number of events that have not been appropriately foreseen. There is no map of regional vulnerability based on the time of occurrence. Hence, the incidence of Acid Resistant Bacteria Positive Pulmonary TB in Madiun city increases, determined by the total number of cases in 6 health centers, seven hospitals, and one prison. In 2015, there were 174 cases, then in 2019, 706 cases. The objective of this study is to predict the number of Acid Resistant Bacteria Positive Pulmonary TB suffering in 2021-2025 based on gender, health centers, and prisons in Madiun City and the overall incidence of cases in 2015-2019 is then foreseen in 2021 to 2025. This type of research is descriptive study research by employing Eviews with the ARIMA method. The population and samples in the study were all data of Acid Resistant Bacteria Positive Pulmonary TB case encompassing the sex of patients during 2015-2019 in Madiun City. The study aimed to predict the incidence of Acid Resistant Bacteria Positive Pulmonary TB in 2021-2025. The results of this study revealed the projection of Acid Resistant Bacteria Positive Pulmonary TB cases based on gender, health centers, hospitals, and prisons in Madiun City from 2020-2025, which experienced an increasing trend with the number of 933, 992, 1063, 1120, 1190 incidences respectively. This study is recommended for relevant agencies or health services to perform preventive efforts by involving trained policymakers and Health Cadis, particularly in preventing TB disease and reducing the high rate of predicting positive pulmonary TB smear incidences in the future.","PeriodicalId":34064,"journal":{"name":"Jurnal Info Kesehatan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43998668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-30DOI: 10.31965/infokes.vol19.iss1.497
P. Tenda, Eleonora Maryeta Toyo
Mulberry leaves are one of the medicinal plants empirically used by people to reduce cholesterol levels. Previous study found that mulberry leaves contain flavonoids, act as cholesterol-lowering and tannins function to inhibit the absorption of food, including fat in the GI tract. The objective of this study is to determine the effect of mulberry leaf ethanol extract on increased HDL levels and to determine the inhibition of the formation of foam cells in male Wistar strain rats given the atherogenic diet. Thirty male Wistar rats were divided into six groups, which were normal group, negative control, positive control, and three groups of mulberry leaf extract at a dose of 25, 50, and 100 mg/200g BW rats, respectively. The HDL levels were measured pre- and post- treatment on days 0, 28, 35 and 42. The results showed that the most effective dose augmenting the HDL as well as inhibited the formation of aortic wall foam cell was the ethanol extract at a dose of 100 mg/200 g BW. In conclusion, mulberry leaves ethanolic extract have the potency to be developed as a natural cholesterol-lowering agent.
桑叶是人们根据经验用来降低胆固醇水平的药用植物之一。先前的研究发现，桑叶含有黄酮类化合物，具有降低胆固醇和单宁的作用，可以抑制食物的吸收，包括胃肠道中的脂肪。本研究的目的是确定桑叶乙醇提取物对高密度脂蛋白水平升高的影响，并确定给予致动脉粥样硬化饮食的雄性Wistar品系大鼠对泡沫细胞形成的抑制作用。30只雄性Wistar大鼠分为6组，分别为正常组、阴性对照组、阳性对照组和桑叶提取物3组，剂量分别为25、50和100mg/200g BW大鼠。在治疗前和治疗后第0、28、35和42天测量HDL水平。结果表明，乙醇提取物在100 mg/200 g BW的剂量下，对高密度脂蛋白的增强和抑制主动脉壁泡沫细胞的形成最有效。因此，桑叶乙醇提取物具有开发天然降胆固醇剂的潜力。
{"title":"Anti-Cholesterolemic Activity of Mulberry (Morus australis Poir) Ethanol Extract in Increasing HDL Levels and Inhibiting Formation of Foam Cells on Rat","authors":"P. Tenda, Eleonora Maryeta Toyo","doi":"10.31965/infokes.vol19.iss1.497","DOIUrl":"https://doi.org/10.31965/infokes.vol19.iss1.497","url":null,"abstract":"Mulberry leaves are one of the medicinal plants empirically used by people to reduce cholesterol levels. Previous study found that mulberry leaves contain flavonoids, act as cholesterol-lowering and tannins function to inhibit the absorption of food, including fat in the GI tract. The objective of this study is to determine the effect of mulberry leaf ethanol extract on increased HDL levels and to determine the inhibition of the formation of foam cells in male Wistar strain rats given the atherogenic diet. Thirty male Wistar rats were divided into six groups, which were normal group, negative control, positive control, and three groups of mulberry leaf extract at a dose of 25, 50, and 100 mg/200g BW rats, respectively. The HDL levels were measured pre- and post- treatment on days 0, 28, 35 and 42. The results showed that the most effective dose augmenting the HDL as well as inhibited the formation of aortic wall foam cell was the ethanol extract at a dose of 100 mg/200 g BW. In conclusion, mulberry leaves ethanolic extract have the potency to be developed as a natural cholesterol-lowering agent.","PeriodicalId":34064,"journal":{"name":"Jurnal Info Kesehatan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46944808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-30DOI: 10.31965/infokes.vol19.iss1.299
S. Mawaddah, Sulis Tiyawati
The number of cases of low-birth-weight babies at dr. Doris Sylvanus Regional General Hospital, Palangka Raya in 2017 was as many as 378 cases. One of the causes of low birth weight was mothers who smoke actively or passively during pregnancy. The objective of this study is to determine the relationship between passive smoking pregnant women and the incidence of low birth weight at the dr. Doris Sylvanus Regional General Hospital, Palangka Raya. This research is an observational study using a cross-sectional research design and a retrospective approach with a sample of 45 mothers obtained using purposive sampling technique. Data analysis used Chi-Square statistical test. The results of the study found that pregnant women with heavy passive smokers gave birth to babies with low birth weight as many as 28 people (62.2%) and 1 person who did not have low birth weight babies (2.2%). Meanwhile, pregnant women with light passive smokers who gave birth to low birth weight were 12 people (26.7%) and 4 people did not have low birth weight (8.9%). Thus, there is a significant relationship between passive smoking pregnant women and the incidence of low birth weight at dr. Doris Sylvanus Regional General Hospital, Palangka Raya with p = 0.047, OR = 9.33. For further researchers, it is recommended to examine the factors that cause pregnant women to smoke passively with the incidence of low-birth-weight babies.
2017年，帕朗卡拉亚多丽丝·希尔瓦努斯博士地区综合医院的低出生体重婴儿数量多达378例。低出生体重的原因之一是母亲在怀孕期间主动或被动吸烟。本研究的目的是在Palangka Raya的dr. Doris Sylvanus地区总医院确定被动吸烟孕妇与低出生体重发生率之间的关系。本研究是一项观察性研究，采用横断面研究设计和回顾性方法，采用有目的抽样技术获得45名母亲的样本。数据分析采用卡方统计检验。研究结果显示，重度被动吸烟者的孕妇所生低体重儿的人数为28人(62.2%)，未生低体重儿的人数为1人(2.2%)。与此同时，轻度被动吸烟的孕妇中，出生体重低的有12人(26.7%)，没有出生体重低的有4人(8.9%)。因此，Palangka Raya dr. Doris Sylvanus地区总医院被动吸烟孕妇与低出生体重发生率之间存在显著关系，p = 0.047, OR = 9.33。对于进一步的研究人员，建议检查导致孕妇被动吸烟与低出生体重婴儿发生率的因素。
{"title":"Passive Smokers Pregnant Women with Low Birth Weight","authors":"S. Mawaddah, Sulis Tiyawati","doi":"10.31965/infokes.vol19.iss1.299","DOIUrl":"https://doi.org/10.31965/infokes.vol19.iss1.299","url":null,"abstract":"The number of cases of low-birth-weight babies at dr. Doris Sylvanus Regional General Hospital, Palangka Raya in 2017 was as many as 378 cases. One of the causes of low birth weight was mothers who smoke actively or passively during pregnancy. The objective of this study is to determine the relationship between passive smoking pregnant women and the incidence of low birth weight at the dr. Doris Sylvanus Regional General Hospital, Palangka Raya. This research is an observational study using a cross-sectional research design and a retrospective approach with a sample of 45 mothers obtained using purposive sampling technique. Data analysis used Chi-Square statistical test. The results of the study found that pregnant women with heavy passive smokers gave birth to babies with low birth weight as many as 28 people (62.2%) and 1 person who did not have low birth weight babies (2.2%). Meanwhile, pregnant women with light passive smokers who gave birth to low birth weight were 12 people (26.7%) and 4 people did not have low birth weight (8.9%). Thus, there is a significant relationship between passive smoking pregnant women and the incidence of low birth weight at dr. Doris Sylvanus Regional General Hospital, Palangka Raya with p = 0.047, OR = 9.33. For further researchers, it is recommended to examine the factors that cause pregnant women to smoke passively with the incidence of low-birth-weight babies.","PeriodicalId":34064,"journal":{"name":"Jurnal Info Kesehatan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45340626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-30DOI: 10.31965/infokes.vol19.iss1.417
Devianty Octavia, Slahayu Niken Purwandini, M. Hilaria, D. Pangestu
Medication errors are accidental failures in a therapeutic process that lead to and have the potential to cause or harm the patient. Medication errors can endanger patient safety, inconvenience and economic burdens. Medication errors can occur at the prescribing, recording, issuing, and administering stages. Reducing the risk of medication errors is a shared responsibility among patients, healthcare professionals, regulators and the pharmaceutical industry at all levels of healthcare delivery. This research is a quantitative research with a descriptive approach. The population taken was 912 prescriptions written by general practitioners at the PKU Muhammadiyah Cepu Hospital in March-May 2019. The sampling technique used was non-probability sampling, which was total sampling. The instrument used in this study was an observation sheet, then the collected data were processed by editing, coding, scoring, and tabulating stages which were then concluded descriptively. The results showed that the incidence of drug prescribing errors in inpatients at PKU Muhammadiyah Cepu Hospital in March 2019 found that all written prescriptions were 100% administratively incomplete. The incidence of prescription medication errors, especially the doctor's name, was 65.9%, the doctor's practice license number was 100%, the date of the prescription was 48.9%, the sign of R/70.9%, the doctor's initial 48.7% and the patient's address 97.4%. Incomplete administrative prescription writing can result in medication errors that are detrimental to health and add to the economic burden of patients.
{"title":"Medication Error at the Prescribing Phase","authors":"Devianty Octavia, Slahayu Niken Purwandini, M. Hilaria, D. Pangestu","doi":"10.31965/infokes.vol19.iss1.417","DOIUrl":"https://doi.org/10.31965/infokes.vol19.iss1.417","url":null,"abstract":"Medication errors are accidental failures in a therapeutic process that lead to and have the potential to cause or harm the patient. Medication errors can endanger patient safety, inconvenience and economic burdens. Medication errors can occur at the prescribing, recording, issuing, and administering stages. Reducing the risk of medication errors is a shared responsibility among patients, healthcare professionals, regulators and the pharmaceutical industry at all levels of healthcare delivery. This research is a quantitative research with a descriptive approach. The population taken was 912 prescriptions written by general practitioners at the PKU Muhammadiyah Cepu Hospital in March-May 2019. The sampling technique used was non-probability sampling, which was total sampling. The instrument used in this study was an observation sheet, then the collected data were processed by editing, coding, scoring, and tabulating stages which were then concluded descriptively. The results showed that the incidence of drug prescribing errors in inpatients at PKU Muhammadiyah Cepu Hospital in March 2019 found that all written prescriptions were 100% administratively incomplete. The incidence of prescription medication errors, especially the doctor's name, was 65.9%, the doctor's practice license number was 100%, the date of the prescription was 48.9%, the sign of R/70.9%, the doctor's initial 48.7% and the patient's address 97.4%. Incomplete administrative prescription writing can result in medication errors that are detrimental to health and add to the economic burden of patients.","PeriodicalId":34064,"journal":{"name":"Jurnal Info Kesehatan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49133215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-30DOI: 10.31965/infokes.vol19.iss1.466
Siti Sulastri, Herastuti Sulistiyani, F. Khasanah
Sweet and sticky foods are the main energy source for oral bacteria and are directly involved in lowering the pH. Gargling with boiled water after every meal can speed up the pH of the saliva in the mouth to return to normal. The objective of this study is to determine the difference in salivary pH between gargling and without gargling water after consuming sweet foods in elementary school students. The research method used was quasi-experimental with pretest and posttest with control group design. The instrument in this research was a pH meter. The population in this study were students in grades I – V of public elementary schools in Bantul with a total population of 135. The research sample used total sampling. Analysis of the research data was conducted using the Wilcoxon test, Mann Withney and Anova Test. The results showed that the pH of saliva (direct gargling) of water/0 minutes after consuming sweet and sticky foods was before 7.53 after gargling 7.99 increased by 0.46. The pH of gargling saliva 5 minutes before 7.48 after rinsing 7.63 increased 0.15. pH of saliva gargling 10 minutes, that was before 7.31 after gargling 7.3 decreased by 0.18. pH of saliva (without rinsing) water/0 minutes, which was initial pH 7.68 to 7.55 after consuming sweet and sticky foods, decreased 0 ,13. The pH of saliva without rinsing with water for 5 minutes, the initial pH was 7.70 to 7.06, decreased by 0.64. The most effective gargling time on salivary pH was gargling water immediately 0 minutes after consuming sweet and sticky foods. The time without gargling water affecting the pH of saliva after consuming sweet and sticky foods was 5 minutes.
{"title":"Saliva pH between Gargling and without Gargling Water after Consuming Sweet and Sticky Foods","authors":"Siti Sulastri, Herastuti Sulistiyani, F. Khasanah","doi":"10.31965/infokes.vol19.iss1.466","DOIUrl":"https://doi.org/10.31965/infokes.vol19.iss1.466","url":null,"abstract":"Sweet and sticky foods are the main energy source for oral bacteria and are directly involved in lowering the pH. Gargling with boiled water after every meal can speed up the pH of the saliva in the mouth to return to normal. The objective of this study is to determine the difference in salivary pH between gargling and without gargling water after consuming sweet foods in elementary school students. The research method used was quasi-experimental with pretest and posttest with control group design. The instrument in this research was a pH meter. The population in this study were students in grades I – V of public elementary schools in Bantul with a total population of 135. The research sample used total sampling. Analysis of the research data was conducted using the Wilcoxon test, Mann Withney and Anova Test. The results showed that the pH of saliva (direct gargling) of water/0 minutes after consuming sweet and sticky foods was before 7.53 after gargling 7.99 increased by 0.46. The pH of gargling saliva 5 minutes before 7.48 after rinsing 7.63 increased 0.15. pH of saliva gargling 10 minutes, that was before 7.31 after gargling 7.3 decreased by 0.18. pH of saliva (without rinsing) water/0 minutes, which was initial pH 7.68 to 7.55 after consuming sweet and sticky foods, decreased 0 ,13. The pH of saliva without rinsing with water for 5 minutes, the initial pH was 7.70 to 7.06, decreased by 0.64. The most effective gargling time on salivary pH was gargling water immediately 0 minutes after consuming sweet and sticky foods. The time without gargling water affecting the pH of saliva after consuming sweet and sticky foods was 5 minutes.","PeriodicalId":34064,"journal":{"name":"Jurnal Info Kesehatan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49334384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The major drawback of the parallel periapical examination technique is that the holder used can damage the oral tissues and cause discomfort to the patient. The objective of this study is to determine the work efficiency and radiographic quality of the innovative dental x-ray holder which has been made by adding synthetic rubber or silicone to the part of the holder that is in direct contact with the patient. This research is an experimental with a post-test only design. The analysis was performed based on filling out the questionnaire on a Likert scale ranging from 1 to 4. With the criteria 1. Disagree, 2. Sometimes, 3. Agree and 4. Strongly Agree. The test was administered by comparing the holder made with the commonly used Aphrodite holder as a control group. There were 16 repetitions of exposure to the cadaveric skull in obtaining research data for each treatment group. The results of statistical work efficiency testing on the control group resulted in a value of B = 0.125 with a significance of 0.071 and an effect of 10.5%. Meanwhile, for testing the quality of radiographic image, the value of B = 0.125 with a significance of 0.014 and an effect of 18.5% was obtained. The innovative dental x-ray holder using a silicone rubber layer is efficient and the resulting radiographic image quality is good when used in the intraoral examination.
{"title":"Innovation of Dental X-Ray Holder Using Silicone Rubber Coating in Posterior Dental Periapical Intraoral Examination","authors":"Marichatul Jannah, Saifudin Saifudin, Wingghayarie Patra Gandhi","doi":"10.31965/infokes.vol19.iss1.505","DOIUrl":"https://doi.org/10.31965/infokes.vol19.iss1.505","url":null,"abstract":"The major drawback of the parallel periapical examination technique is that the holder used can damage the oral tissues and cause discomfort to the patient. The objective of this study is to determine the work efficiency and radiographic quality of the innovative dental x-ray holder which has been made by adding synthetic rubber or silicone to the part of the holder that is in direct contact with the patient. This research is an experimental with a post-test only design. The analysis was performed based on filling out the questionnaire on a Likert scale ranging from 1 to 4. With the criteria 1. Disagree, 2. Sometimes, 3. Agree and 4. Strongly Agree. The test was administered by comparing the holder made with the commonly used Aphrodite holder as a control group. There were 16 repetitions of exposure to the cadaveric skull in obtaining research data for each treatment group. The results of statistical work efficiency testing on the control group resulted in a value of B = 0.125 with a significance of 0.071 and an effect of 10.5%. Meanwhile, for testing the quality of radiographic image, the value of B = 0.125 with a significance of 0.014 and an effect of 18.5% was obtained. The innovative dental x-ray holder using a silicone rubber layer is efficient and the resulting radiographic image quality is good when used in the intraoral examination.","PeriodicalId":34064,"journal":{"name":"Jurnal Info Kesehatan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47034581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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