Pub Date : 2020-05-17DOI: 10.20862/0042-4676-2020-101-2-126-130
B. Sharafutdinov, S. A. Ryzhkin, E. A. Gaziev, I. V. Abdul’yanov, A. Abashev, M. K. Mikhaylov
The paper describes a clinical case of successfully applying a transradial access during mechanical thrombus extraction in a patient in the acutest stage of ischemic stroke with a congenital anatomical feature (the left common carotid artery and brachiocephalic trunk with the common ostium from the aortic arch).X-ray endovascular interventions were performed in an operating room equipped with a digital angiographic unit including an Axiom Artis dTA flat detector (Siemens Medical System).Mechanical recanalization for acute occlusion of the M2 segment of the left middle cerebral artery (MCA) was carried out using a right radial access into and catheterization of the left internal carotid artery. A stent retriever was inserted into the occlusion area through a microcatheter and was opened. Double thrombus extraction from the left MCA was made using the stent retriever to restore TICI 2B blood flow. There were no signs of dissection, thrombosis, or distal thromboembolism.
本文介绍了一例先天性缺血性中风急性期(左颈总动脉和头臂干与主动脉弓的总开口)患者机械取栓时成功应用经桡动脉通路的临床病例。x线血管内介入手术在配备数字血管造影设备的手术室进行，其中包括Axiom Artis dTA平面探测器(西门子医疗系统)。机械再通术治疗急性闭塞的左大脑中动脉(MCA) M2段，采用右桡动脉通道进入左颈内动脉插管。支架取出器通过微导管插入闭塞区并打开。使用支架回收器从左MCA取出双血栓，恢复TICI 2B血流。没有解剖、血栓形成或远端血栓栓塞的迹象。
{"title":"Mechanical Thrombectomy Using Transradial Access in a Variation of the Origin of the Brachiocephalic Trunk and Left Common Carotid Artery by the Common Ostium from the Aortic Arch","authors":"B. Sharafutdinov, S. A. Ryzhkin, E. A. Gaziev, I. V. Abdul’yanov, A. Abashev, M. K. Mikhaylov","doi":"10.20862/0042-4676-2020-101-2-126-130","DOIUrl":"https://doi.org/10.20862/0042-4676-2020-101-2-126-130","url":null,"abstract":"The paper describes a clinical case of successfully applying a transradial access during mechanical thrombus extraction in a patient in the acutest stage of ischemic stroke with a congenital anatomical feature (the left common carotid artery and brachiocephalic trunk with the common ostium from the aortic arch).X-ray endovascular interventions were performed in an operating room equipped with a digital angiographic unit including an Axiom Artis dTA flat detector (Siemens Medical System).Mechanical recanalization for acute occlusion of the M2 segment of the left middle cerebral artery (MCA) was carried out using a right radial access into and catheterization of the left internal carotid artery. A stent retriever was inserted into the occlusion area through a microcatheter and was opened. Double thrombus extraction from the left MCA was made using the stent retriever to restore TICI 2B blood flow. There were no signs of dissection, thrombosis, or distal thromboembolism.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67729279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-17DOI: 10.20862/0042-4676-2020-101-2-103-112
K. A. Zavylova, B. Shakhov, S. V. Morovov
Objective. To optimize a pelvic and lower abdominal cavity MRI protocol in the diagnosis of chronic pelvic pain (CPP) in women.Material and methods. A total of 57 reproductive-aged women with complaints of CPP were examined. The first stage of all patients after clinical and laboratory examination for clinical indications was performed ultrasound of the pelvis and abdominal cavity with dopplerometry. In the second stage, all the patients underwent an MRI using the standard Protocol, and then a modified Protocol. The final diagnosis was based on the results of a comprehensive examination, which included a clinical and neurological examination, gynecological examination, pelvic and abdominal ultrasound, radiography of the ileosacral joints and lumbosacral spine, fibrocolonoscopy and laparoscopy with morphological examination of the operating material (according to indications).Results. Forty-six (81%) patients were found to have gynecological factors for the development of CPP; 16 (28%) had extragenital factors. The examination results were verified by the data of surgical intervention (n = 16 (28%)), hysteroscopy (n = 21 (37%)), and laparoscopy (n = 9 (16%)) with morphological examination of biopsy specimens or surgical material.Comparing with the standard pelvic MR protocol provided evidence for the high diagnostic value of the modified protocol statistically significantly (p < 0.05): 99.2% sensitivity and 99.6% specificity.Conclusion. The developed non-contrast 1.5T MRI protocol for the pelvis permits MR images of the pelvis and adjacent anatomical areas to be obtained during one study without increasing time expenditures and upgrading equipment and software. The use of the protocol makes it possible to improve the quality of radiation diagnosis of gynecological and extragenital diseases in CPP and to recommend that the protocol in combination with other clinical and instrumental studies be introduced in clinical practice.
{"title":"An Optimized Procedure for Non-Contrast Magnetic Resonance Imaging in the Diagnosis of Chronic Pelvic Pain in Women","authors":"K. A. Zavylova, B. Shakhov, S. V. Morovov","doi":"10.20862/0042-4676-2020-101-2-103-112","DOIUrl":"https://doi.org/10.20862/0042-4676-2020-101-2-103-112","url":null,"abstract":"Objective. To optimize a pelvic and lower abdominal cavity MRI protocol in the diagnosis of chronic pelvic pain (CPP) in women.Material and methods. A total of 57 reproductive-aged women with complaints of CPP were examined. The first stage of all patients after clinical and laboratory examination for clinical indications was performed ultrasound of the pelvis and abdominal cavity with dopplerometry. In the second stage, all the patients underwent an MRI using the standard Protocol, and then a modified Protocol. The final diagnosis was based on the results of a comprehensive examination, which included a clinical and neurological examination, gynecological examination, pelvic and abdominal ultrasound, radiography of the ileosacral joints and lumbosacral spine, fibrocolonoscopy and laparoscopy with morphological examination of the operating material (according to indications).Results. Forty-six (81%) patients were found to have gynecological factors for the development of CPP; 16 (28%) had extragenital factors. The examination results were verified by the data of surgical intervention (n = 16 (28%)), hysteroscopy (n = 21 (37%)), and laparoscopy (n = 9 (16%)) with morphological examination of biopsy specimens or surgical material.Comparing with the standard pelvic MR protocol provided evidence for the high diagnostic value of the modified protocol statistically significantly (p < 0.05): 99.2% sensitivity and 99.6% specificity.Conclusion. The developed non-contrast 1.5T MRI protocol for the pelvis permits MR images of the pelvis and adjacent anatomical areas to be obtained during one study without increasing time expenditures and upgrading equipment and software. The use of the protocol makes it possible to improve the quality of radiation diagnosis of gynecological and extragenital diseases in CPP and to recommend that the protocol in combination with other clinical and instrumental studies be introduced in clinical practice.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67729259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-23DOI: 10.20862/0042-4676-2020-101-1-39-46
N. Klimova, A. Ilkanich, V. Darvin, A. L. Koctrubin, T. Vardanyan, F. Aliev
Objective: to analyze the diagnostic value of radiation techniques in patients with opisthorchiasis-induced obstructive jaundice and to determine the types of bile duct (BD) changes characteristic of this disease.Subjects and methods. The investigation enrolled 103 patients with chronic opisthorchiasis complicated by obstructive jaundice. For BD visualization, the investigators used radiation diagnostic methods, such as ultrasonography (USG), magnetic resonance cholangiopancreatography (MRCP), and endoscopic retrograde cholangiopancreatography (ERCP); their efficiency was evaluated.Results. ERCP and MRCP could identify 5 types of BD architectonics in opisthorchiasis-induced obstructive jaundice. The sensitivity, specificity, and overall accuracy of MRCP in diagnosing opisthorchiasis-induced sclerotic changes were 98.1, 87.5, and 96.8%, respectively.Conclusion. Among instrumental methods for diagnosing sclerotic BD changes in prolonged opisthorchiasis invasion, it is preferable to use MRCP, which is determined by its high informative value. Five types of cholangioarchitectonics are detectable in chronic opisthorchiasis complicated by obstructive jaundice.
{"title":"Radiation study techniques in diagnosing the causes of opisthorchiasis-induced obstructive jaundice","authors":"N. Klimova, A. Ilkanich, V. Darvin, A. L. Koctrubin, T. Vardanyan, F. Aliev","doi":"10.20862/0042-4676-2020-101-1-39-46","DOIUrl":"https://doi.org/10.20862/0042-4676-2020-101-1-39-46","url":null,"abstract":"Objective: to analyze the diagnostic value of radiation techniques in patients with opisthorchiasis-induced obstructive jaundice and to determine the types of bile duct (BD) changes characteristic of this disease.Subjects and methods. The investigation enrolled 103 patients with chronic opisthorchiasis complicated by obstructive jaundice. For BD visualization, the investigators used radiation diagnostic methods, such as ultrasonography (USG), magnetic resonance cholangiopancreatography (MRCP), and endoscopic retrograde cholangiopancreatography (ERCP); their efficiency was evaluated.Results. ERCP and MRCP could identify 5 types of BD architectonics in opisthorchiasis-induced obstructive jaundice. The sensitivity, specificity, and overall accuracy of MRCP in diagnosing opisthorchiasis-induced sclerotic changes were 98.1, 87.5, and 96.8%, respectively.Conclusion. Among instrumental methods for diagnosing sclerotic BD changes in prolonged opisthorchiasis invasion, it is preferable to use MRCP, which is determined by its high informative value. Five types of cholangioarchitectonics are detectable in chronic opisthorchiasis complicated by obstructive jaundice.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67729148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-23DOI: 10.20862/0042-4676-2020-101-1-58-66
A. Gonchar, V. A. Gombolevskij, A. B. Elizarov, N. S. Kulberg, M. M. Suleymanova, T. I. Alekseeva, D. Chernyshev, M. Titov, T. Levina, V. Bosin, S. Morozov
With allowance made for the widespread prevalence of diffuse liver diseases, non-alcoholic fatty liver disease in particular, there is a need for the most objective evaluation of the state of this organ. One of the most important criteria for this evaluation is to estimate liver tissue density values. Today, the introduction of programs, such as lung cancer screening using low-dose computed tomography, has made it possible to conduct mass surveys in this area. This literature review deals with the advantages and disadvantages of computed tomography in detecting diffuse liver lesions.
{"title":"Possibilities of liver density estimation according to noncontrast computed tomography","authors":"A. Gonchar, V. A. Gombolevskij, A. B. Elizarov, N. S. Kulberg, M. M. Suleymanova, T. I. Alekseeva, D. Chernyshev, M. Titov, T. Levina, V. Bosin, S. Morozov","doi":"10.20862/0042-4676-2020-101-1-58-66","DOIUrl":"https://doi.org/10.20862/0042-4676-2020-101-1-58-66","url":null,"abstract":"With allowance made for the widespread prevalence of diffuse liver diseases, non-alcoholic fatty liver disease in particular, there is a need for the most objective evaluation of the state of this organ. One of the most important criteria for this evaluation is to estimate liver tissue density values. Today, the introduction of programs, such as lung cancer screening using low-dose computed tomography, has made it possible to conduct mass surveys in this area. This literature review deals with the advantages and disadvantages of computed tomography in detecting diffuse liver lesions.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67729157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-26DOI: 10.20862/0042-4676-2019-100-6-372-378
I. Korobkova, D. A. Dremin, S. M. Kakalov, I. Kirsan', I. S. Skrynnikov, A. A. Ugrimov, M. N. Sorokin
The paper gives a clinical example of diagnosing hepatic epithelioid hemangioendothelioma. With allowance made for that the tumor occurs rarely (less than 1% of cases of all vascular tumors), the authors provide the clinical example to demonstrate the capabilities of imaging techniques, by applying an integrated approach.
{"title":"Hepatic Epithelioid Hemangioendothelioma","authors":"I. Korobkova, D. A. Dremin, S. M. Kakalov, I. Kirsan', I. S. Skrynnikov, A. A. Ugrimov, M. N. Sorokin","doi":"10.20862/0042-4676-2019-100-6-372-378","DOIUrl":"https://doi.org/10.20862/0042-4676-2019-100-6-372-378","url":null,"abstract":"The paper gives a clinical example of diagnosing hepatic epithelioid hemangioendothelioma. With allowance made for that the tumor occurs rarely (less than 1% of cases of all vascular tumors), the authors provide the clinical example to demonstrate the capabilities of imaging techniques, by applying an integrated approach.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49221721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-04DOI: 10.20862/0042-4676-2019-100-5-304-308
M. B. Sukhova, А. Medvedev
The review presents a rare clinical case of right-sided infective endocarditis (IE), a variant of early diagnosis using contrast-enhanced multispiral computed tomography (CE-MSCT), and successful surgical treatment for septic pulmonary embolism and right-sided IE. The clinical manifestation of the disease lasted about 3 weeks. The diagnosis was established according to the results of an emergency complex CE-MSCT study. At 4 hours after the patient went to the clinic, a combined operation (removal of part of the venous port and thrombectomy from the left pulmonary branch) was successfully performed. There was a complete coincidence of CE-MSCT study data and intraoperative results; staphylococcal septic focus was confirmed in a laboratory. The total length of stay in hospital was 9 days; that of full performance restoration was 3 weeks. The presented case has proven that the CE-MSCT may be the only sufficient technique for detecting septic pulmonary embolism and deciding in favor of surgical treatment, eliminating the need for a different kind of instrumental diagnosis, which significantly reduces the time of diagnosis.
{"title":"Early Сontrast-Enhanced Multispiral Computed Tomographic Diagnosis of Septic Pulmonary Embolism and a Case of Successful Surgical Treatment","authors":"M. B. Sukhova, А. Medvedev","doi":"10.20862/0042-4676-2019-100-5-304-308","DOIUrl":"https://doi.org/10.20862/0042-4676-2019-100-5-304-308","url":null,"abstract":"The review presents a rare clinical case of right-sided infective endocarditis (IE), a variant of early diagnosis using contrast-enhanced multispiral computed tomography (CE-MSCT), and successful surgical treatment for septic pulmonary embolism and right-sided IE. The clinical manifestation of the disease lasted about 3 weeks. The diagnosis was established according to the results of an emergency complex CE-MSCT study. At 4 hours after the patient went to the clinic, a combined operation (removal of part of the venous port and thrombectomy from the left pulmonary branch) was successfully performed. There was a complete coincidence of CE-MSCT study data and intraoperative results; staphylococcal septic focus was confirmed in a laboratory. The total length of stay in hospital was 9 days; that of full performance restoration was 3 weeks. The presented case has proven that the CE-MSCT may be the only sufficient technique for detecting septic pulmonary embolism and deciding in favor of surgical treatment, eliminating the need for a different kind of instrumental diagnosis, which significantly reduces the time of diagnosis.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67729140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-04DOI: 10.20862/0042-4676-2019-100-5-247-253
Y. Varlamova, Yurii Lishmanov, I. Kisteneva
Objective. To identify the scintigraphic predictors of the efficiency of interventional treatment for atrial fibrillation (AF) by cardiac 123I-metaiodobenzylguanidine (123I-MIBG) radionuclide scanning.Material and methods. The investigation enrolled 35 patients with AF concurrent with hypertensive disease (HD): 17 persons with persistent AF (PAF) and 18 patients with long-standing PAF (LPAF). In addition, 10 patients with HD without arrhythmia signs were examined as a comparison group. All the patients with AF before radiofrequency ablation (RFA) and those with sinus rhythm underwent 123I-MIBG myocardial scintigraphy to assess the sympathetic innervation of the heart. The efficiency of RFA was evaluated after 12 months by 24-hour ECG monitoring.Results. The patients of both groups were divided into subgroups according to the presence of recurrent arrhythmia one year after interventional treatment. ROC analysis could determine the main scintigraphic predictors of the efficiency of RFA. The preoperative indicators, in which the subgroups with and without recurrent AF showed significant differences, were studied. In the patients with PAF, the delayed Heart/ Mediastinum (H/M) ratio cutoff was ≥1.55 (the area under the ROC curve was 0.929; 100% sensitivity and 57% specificity), and the threshold value of 123I-MIBG washout rate was ≤22.3% (the area under ROC curve was 0.957; 100% sensitivity and 43% specificity) may suggest that RFA is effective. In the patients with LPAF, the threshold values of early H/M ratio were ≥1.69 (the area under the ROC curve was 0.849; 100% sensitivity and 62% specificity) and those of delayed H/M ratio were ≥1.66 (the area under the ROC curve was 0.938; 94% sensitivity and 23% specificity) allow the prediction of a risk for postoperative recurrent AF.Conclusion. The findings suggest that 123I-MIBG scintigraphy can be used to predict a high risk for recurrent AF after RFA of the pathological pathways of a pulse in the myocardium.
{"title":"The Prognostic Value of the Results of 123I-metaiodobenzylguanidine Myocardial Scintigraphy in the Examination of Patients with Atrial Fibrillation Referred for Its Interventional Treatment","authors":"Y. Varlamova, Yurii Lishmanov, I. Kisteneva","doi":"10.20862/0042-4676-2019-100-5-247-253","DOIUrl":"https://doi.org/10.20862/0042-4676-2019-100-5-247-253","url":null,"abstract":"Objective. To identify the scintigraphic predictors of the efficiency of interventional treatment for atrial fibrillation (AF) by cardiac 123I-metaiodobenzylguanidine (123I-MIBG) radionuclide scanning.Material and methods. The investigation enrolled 35 patients with AF concurrent with hypertensive disease (HD): 17 persons with persistent AF (PAF) and 18 patients with long-standing PAF (LPAF). In addition, 10 patients with HD without arrhythmia signs were examined as a comparison group. All the patients with AF before radiofrequency ablation (RFA) and those with sinus rhythm underwent 123I-MIBG myocardial scintigraphy to assess the sympathetic innervation of the heart. The efficiency of RFA was evaluated after 12 months by 24-hour ECG monitoring.Results. The patients of both groups were divided into subgroups according to the presence of recurrent arrhythmia one year after interventional treatment. ROC analysis could determine the main scintigraphic predictors of the efficiency of RFA. The preoperative indicators, in which the subgroups with and without recurrent AF showed significant differences, were studied. In the patients with PAF, the delayed Heart/ Mediastinum (H/M) ratio cutoff was ≥1.55 (the area under the ROC curve was 0.929; 100% sensitivity and 57% specificity), and the threshold value of 123I-MIBG washout rate was ≤22.3% (the area under ROC curve was 0.957; 100% sensitivity and 43% specificity) may suggest that RFA is effective. In the patients with LPAF, the threshold values of early H/M ratio were ≥1.69 (the area under the ROC curve was 0.849; 100% sensitivity and 62% specificity) and those of delayed H/M ratio were ≥1.66 (the area under the ROC curve was 0.938; 94% sensitivity and 23% specificity) allow the prediction of a risk for postoperative recurrent AF.Conclusion. The findings suggest that 123I-MIBG scintigraphy can be used to predict a high risk for recurrent AF after RFA of the pathological pathways of a pulse in the myocardium.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46722163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-04DOI: 10.20862/0042-4676-2019-100-5-293-297
Maksim V. Egorov, Valentin E. Sinitsyn, Аleksandr V. Bakunovich
Objective. To evaluate the efficiency of magnetic resonance spectroscopy in the diagnosis and prognosis of breast cancer (BC).Material and methods. Twenty-eight patients aged 37 to 80 years with established primary invasive BC were examined. Its grade was determined according to pathomorphological verification with immunohistochemical analysis. Breast MRI was performed using the standard protocol, by determining the measured diffusion coefficient (MDC), dynamic contrast enhancement (DCE). Proton magnetic resonance spectroscopy was carried out using the Breeze software package. The clinical and morphological findings and the results of radiation studies were compared to determine Nottingham prognostic index (NPI) scores. To identify the Spearman rank correlation coefficient between MRI findings (the type of pharmacokinetic curves, the total choline-containing (tCho) peak integral) and the values characterizing tumor size and grade.Results. NPI calculation showed that the scoring range was 2.4 to 6.76; the expected 5-year survival rates reached 93%. The mean MDC was 0.856×10-3 mm2/sec; type II pharmacokinetic curve prevailed (n=16; 57.1%). There was a statistically significant negative correlation between the values of MDC, the type of a contrast agent accumulation curve, the levels of HER2/neu and the proliferation marker Ki-67; there was a statistically significant strong positive correlation between the presence of 1H-MPC tCho peak and the indicators determining tumor malignancy (the levels of HER2/neu and Ki-67). Statistically significant differences between the type of a pharmacokinetic curve in DCE and the level of tCho in the prognostic groups defined when calculating NPI were determined in patients with moderate (n=4; 14.2%) and poor (n=10; 35.7%) prognosis.Conclusion. The capabilities of MR spectroscopy are superior in information content to the data obtained by determining the MDC, the nature of contrast medium accumulation in breast tumor, and are comparable with the data determining the type of a tumor (the presence of the HER2/neu gene, Ki-67 proliferation marker) in predicting BC cancer grade and 5-year survival rates.
{"title":"Magnetic Resonance Spectroscopy in the Diagnosis and Prognosis of Breast Cancer","authors":"Maksim V. Egorov, Valentin E. Sinitsyn, Аleksandr V. Bakunovich","doi":"10.20862/0042-4676-2019-100-5-293-297","DOIUrl":"https://doi.org/10.20862/0042-4676-2019-100-5-293-297","url":null,"abstract":"Objective. To evaluate the efficiency of magnetic resonance spectroscopy in the diagnosis and prognosis of breast cancer (BC).Material and methods. Twenty-eight patients aged 37 to 80 years with established primary invasive BC were examined. Its grade was determined according to pathomorphological verification with immunohistochemical analysis. Breast MRI was performed using the standard protocol, by determining the measured diffusion coefficient (MDC), dynamic contrast enhancement (DCE). Proton magnetic resonance spectroscopy was carried out using the Breeze software package. The clinical and morphological findings and the results of radiation studies were compared to determine Nottingham prognostic index (NPI) scores. To identify the Spearman rank correlation coefficient between MRI findings (the type of pharmacokinetic curves, the total choline-containing (tCho) peak integral) and the values characterizing tumor size and grade.Results. NPI calculation showed that the scoring range was 2.4 to 6.76; the expected 5-year survival rates reached 93%. The mean MDC was 0.856×10-3 mm2/sec; type II pharmacokinetic curve prevailed (n=16; 57.1%). There was a statistically significant negative correlation between the values of MDC, the type of a contrast agent accumulation curve, the levels of HER2/neu and the proliferation marker Ki-67; there was a statistically significant strong positive correlation between the presence of 1H-MPC tCho peak and the indicators determining tumor malignancy (the levels of HER2/neu and Ki-67). Statistically significant differences between the type of a pharmacokinetic curve in DCE and the level of tCho in the prognostic groups defined when calculating NPI were determined in patients with moderate (n=4; 14.2%) and poor (n=10; 35.7%) prognosis.Conclusion. The capabilities of MR spectroscopy are superior in information content to the data obtained by determining the MDC, the nature of contrast medium accumulation in breast tumor, and are comparable with the data determining the type of a tumor (the presence of the HER2/neu gene, Ki-67 proliferation marker) in predicting BC cancer grade and 5-year survival rates.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67729043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-09DOI: 10.20862/0042-4676-2019-100-4-186-191
T. Safonova, S. Kharlap, O. Eksarenko
Objective. To identify clinical and morphofunctional changes in the lacrimal gland in sarcoidosis.Material and methods. Ultrasonography was conducted in 53 patients (106 eyes) with a verified diagnosis of systemic sarcoidosis (7 men and 46 women) whose age was 31 to 72 years.Results. Different types of lacrimal gland structural changes in sarcoidosis were detected. Comparing the acoustic and functional findings revealed a high correlation (r > 0.7) between these parameters as vascularization index, a reflex component of tear secretion, and the presence of tubular structures. Types of changes in the acoustic structure of the lacrimal glands were identified, which were designated as edematous and polymorphic changes, as well as atrophic changes with a necrotic component.Conclusion. The findings can be used to diagnose lacrimal gland changes in patients suffering from sarcoidosis.
{"title":"Ultrasonic Predictors of Dry Eye Syndrome in Sarcoidosis","authors":"T. Safonova, S. Kharlap, O. Eksarenko","doi":"10.20862/0042-4676-2019-100-4-186-191","DOIUrl":"https://doi.org/10.20862/0042-4676-2019-100-4-186-191","url":null,"abstract":"Objective. To identify clinical and morphofunctional changes in the lacrimal gland in sarcoidosis.Material and methods. Ultrasonography was conducted in 53 patients (106 eyes) with a verified diagnosis of systemic sarcoidosis (7 men and 46 women) whose age was 31 to 72 years.Results. Different types of lacrimal gland structural changes in sarcoidosis were detected. Comparing the acoustic and functional findings revealed a high correlation (r > 0.7) between these parameters as vascularization index, a reflex component of tear secretion, and the presence of tubular structures. Types of changes in the acoustic structure of the lacrimal glands were identified, which were designated as edematous and polymorphic changes, as well as atrophic changes with a necrotic component.Conclusion. The findings can be used to diagnose lacrimal gland changes in patients suffering from sarcoidosis.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67729133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-09DOI: 10.20862/0042-4676-2019-100-4-229-236
I. Krotenkova, V. Bryukhov, R. Konovalov, M. Zakharova, M. Krotenkova
The diagnosis of multiple sclerosis (MS) is quite complicated, which is associated with its clinical features and the lack of unique confirmatory tests. Magnetic resonance imaging (MRI) is one of the ways to confirm the diagnosis and also makes it possible to establish a differential diagnosis with other demyelinating diseases and to exclude diseases that mimic MS. This review presents not only MRI criteria for MS and other diseases similar to the MRI pattern, but also additional clinical and laboratory data, without which it is impossible to make a correct diagnosis.
{"title":"Magnetic Resonance Imaging in the Differential Diagnosis of Multiple Sclerosis and Other Demyelinating Diseases","authors":"I. Krotenkova, V. Bryukhov, R. Konovalov, M. Zakharova, M. Krotenkova","doi":"10.20862/0042-4676-2019-100-4-229-236","DOIUrl":"https://doi.org/10.20862/0042-4676-2019-100-4-229-236","url":null,"abstract":"The diagnosis of multiple sclerosis (MS) is quite complicated, which is associated with its clinical features and the lack of unique confirmatory tests. Magnetic resonance imaging (MRI) is one of the ways to confirm the diagnosis and also makes it possible to establish a differential diagnosis with other demyelinating diseases and to exclude diseases that mimic MS. This review presents not only MRI criteria for MS and other diseases similar to the MRI pattern, but also additional clinical and laboratory data, without which it is impossible to make a correct diagnosis.","PeriodicalId":34090,"journal":{"name":"Vestnik rentgenologii i radiologii","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49352949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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