Pub Date : 2022-08-15DOI: 10.29052/ijehsr.v10.i3.2022.355-360
Aurangzeb Kalhoro, Lal Rehman, Abdul Samad Panezai, S. Hassan, Farrukh Javeed
Background: Head trauma is the most common case encountered in neurosurgery, and it is on the rise daily; head trauma sometimes requires the removal of skull bone which leads to another set of complications and associated issues related to cranioplasty. The study's objective was to share the single-center tertiary care hospital experience of cranioplasty, including outcomes, management, and associated complications. Methodology: Patients who underwent reconstructive cranioplasty at the study site from 2015-2020 were examined in this retrospective descriptive study conducted at the department of neurosurgery, Jinnah postgraduate medical center, Karachi. Patients aged 18 to 60 years were considered for cranioplasty procedures, preceded by the decompressive post-craniotomy for brain trauma, skull fracture, intractable intracranial hypertension, brain tumor, and infected post-craniotomy bone flaps were included in the study. Results: A total of 68 patients who presented to the study center with cranial defects were included in this study. The frequent cause of cranioplasty was the traumatic injury to the brain in 38(55.88%), followed by brain tumors in 321(0.4%) and cerebrovascular injury in 9(13.23%) cases. In our study, no patient required more than one cranial procedure. The anatomical regional wise division of defects was temporal 29(42.64%), frontal 15(22%), and parietal 24(35.39%). Conclusion: Indications for cranioplasty, type of bone graft, associated comorbidities, and complications have been addressed that are potentially preventable.
{"title":"The experience of cranioplasty outcome, management and its complication in neurosurgery","authors":"Aurangzeb Kalhoro, Lal Rehman, Abdul Samad Panezai, S. Hassan, Farrukh Javeed","doi":"10.29052/ijehsr.v10.i3.2022.355-360","DOIUrl":"https://doi.org/10.29052/ijehsr.v10.i3.2022.355-360","url":null,"abstract":"Background: Head trauma is the most common case encountered in neurosurgery, and it is on the rise daily; head trauma sometimes requires the removal of skull bone which leads to another set of complications and associated issues related to cranioplasty. The study's objective was to share the single-center tertiary care hospital experience of cranioplasty, including outcomes, management, and associated complications. Methodology: Patients who underwent reconstructive cranioplasty at the study site from 2015-2020 were examined in this retrospective descriptive study conducted at the department of neurosurgery, Jinnah postgraduate medical center, Karachi. Patients aged 18 to 60 years were considered for cranioplasty procedures, preceded by the decompressive post-craniotomy for brain trauma, skull fracture, intractable intracranial hypertension, brain tumor, and infected post-craniotomy bone flaps were included in the study. Results: A total of 68 patients who presented to the study center with cranial defects were included in this study. The frequent cause of cranioplasty was the traumatic injury to the brain in 38(55.88%), followed by brain tumors in 321(0.4%) and cerebrovascular injury in 9(13.23%) cases. In our study, no patient required more than one cranial procedure. The anatomical regional wise division of defects was temporal 29(42.64%), frontal 15(22%), and parietal 24(35.39%). Conclusion: Indications for cranioplasty, type of bone graft, associated comorbidities, and complications have been addressed that are potentially preventable.","PeriodicalId":34196,"journal":{"name":"International Journal of Endorsing Health Science Research","volume":"287 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41284106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-15DOI: 10.29052/ijehsr.v10.i3.2022.304-312
S. Shah, Muhmmad Arsalan Ghazi, M. Sufyan, Muhammad Mustafa, K. Najjad, A. Peracha
Background: In the geriatric population, osteoporotic or fragility hip fractures hold a significant health burden and are scrupulously linked with a greater possibility of morbidity and mortality among this population group, even though there is an increased incidence of subsequent hip fractures. Bisphosphonates are extensively used in treating and preventing fragility hip fractures as prophetically. Methodology: From March 2014 to February 2020, a total of 2430 patients were enrolled with their first hip fracture. After determining the second hip fracture, a comparison between non-compliant and compliant bisphosphonate users (Ibandronic Acid) was conducted. Medication Possession Ratio of more than 80% post first hip fracture treatment was defined as bisphosphonates compliant user. Results: Among 2430 patients, 65.2 years was the mean age at the first hip fracture (ranging from 51 to 91 years). A total of 146 (6.0%) patients suffered from second hip fractures at a mean duration of 29.45 months post first hip fracture. 2nd hip fracture was observed in only 3.5% (30/860) of compliant bisphosphonate users compared to non-compliant users with 7.4% (116/1570). Conclusion: Among the geriatric population, the use of bisphosphonate (Ibandronic Acid) has a significant impact on preventing subsequent hip fractures. Hence this emphasizes the need to use bisphosphonates in clinical practice to help to minimize the burden of hip fractures.
{"title":"Prevention of Subsequent Hip Fractures among Geriatric Population with Use of Bisphosphonates.","authors":"S. Shah, Muhmmad Arsalan Ghazi, M. Sufyan, Muhammad Mustafa, K. Najjad, A. Peracha","doi":"10.29052/ijehsr.v10.i3.2022.304-312","DOIUrl":"https://doi.org/10.29052/ijehsr.v10.i3.2022.304-312","url":null,"abstract":"Background: In the geriatric population, osteoporotic or fragility hip fractures hold a significant health burden and are scrupulously linked with a greater possibility of morbidity and mortality among this population group, even though there is an increased incidence of subsequent hip fractures. Bisphosphonates are extensively used in treating and preventing fragility hip fractures as prophetically. Methodology: From March 2014 to February 2020, a total of 2430 patients were enrolled with their first hip fracture. After determining the second hip fracture, a comparison between non-compliant and compliant bisphosphonate users (Ibandronic Acid) was conducted. Medication Possession Ratio of more than 80% post first hip fracture treatment was defined as bisphosphonates compliant user. Results: Among 2430 patients, 65.2 years was the mean age at the first hip fracture (ranging from 51 to 91 years). A total of 146 (6.0%) patients suffered from second hip fractures at a mean duration of 29.45 months post first hip fracture. 2nd hip fracture was observed in only 3.5% (30/860) of compliant bisphosphonate users compared to non-compliant users with 7.4% (116/1570). Conclusion: Among the geriatric population, the use of bisphosphonate (Ibandronic Acid) has a significant impact on preventing subsequent hip fractures. Hence this emphasizes the need to use bisphosphonates in clinical practice to help to minimize the burden of hip fractures.","PeriodicalId":34196,"journal":{"name":"International Journal of Endorsing Health Science Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42673780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: In the recent past, numerous researchers have analyzed dissimilar aspects of osteoporosis in liver cirrhosis, we still have deficient indigenous literature. The present study aims to determine the frequency of osteoporosis with liver cirrhosis. Methodology: A prospective observational study was carried out at the Tertiary referral center of Karachi. Osteoporosis of liver cirrhosis patients was established as specified by WHO using dual-energy X-ray absorptiometry (DXA) on the L1-L4 spine and having spine bone mineral density (BMD) expressed as T score <-2.5. Short history related to the duration of the disease was recorded. The patient's BMD expressed as a T score was measured using DXA on the spine. Results: Among patients who had presented with a duration of cirrhosis of 5 years or less, 20(6.75%) had osteoporosis, whereas 62(20.9%) had it with a duration > 5 years (p=0.000). As far as outcome of the patients is concerned 52(17.5%) and 30(10.1%) patients had osteoporosis with BMI < 25 kg/m2 and > 25 kg/m2 respectively (p=0.590). When layered according to the Childs Class, among patients with Class A, B, and C, 0.33%, 3.37%, and 23.9% of patients had osteoporosis (p=0.050). Conclusion: In conclusion, the prevalence of osteoporosis in patients with cirrhosis was found to be 27.7%. Furthermore, patients with a longer duration of disease, low BMI, and with child class C are at greater threat of the occurrence of osteoporosis and require early detection and prompt treatment.
{"title":"Prevalence of osteoporosis in patients with liver cirrhosis.","authors":"Shaista Ahmed, Sadia Iqbal, Afshan Siddiqui, Mujtaba Hassan, Aisha Ahmed, A. Altaf","doi":"10.29052/ijehsr.v10.i3.2022.273-278","DOIUrl":"https://doi.org/10.29052/ijehsr.v10.i3.2022.273-278","url":null,"abstract":"Background: In the recent past, numerous researchers have analyzed dissimilar aspects of osteoporosis in liver cirrhosis, we still have deficient indigenous literature. The present study aims to determine the frequency of osteoporosis with liver cirrhosis. Methodology: A prospective observational study was carried out at the Tertiary referral center of Karachi. Osteoporosis of liver cirrhosis patients was established as specified by WHO using dual-energy X-ray absorptiometry (DXA) on the L1-L4 spine and having spine bone mineral density (BMD) expressed as T score <-2.5. Short history related to the duration of the disease was recorded. The patient's BMD expressed as a T score was measured using DXA on the spine. Results: Among patients who had presented with a duration of cirrhosis of 5 years or less, 20(6.75%) had osteoporosis, whereas 62(20.9%) had it with a duration > 5 years (p=0.000). As far as outcome of the patients is concerned 52(17.5%) and 30(10.1%) patients had osteoporosis with BMI < 25 kg/m2 and > 25 kg/m2 respectively (p=0.590). When layered according to the Childs Class, among patients with Class A, B, and C, 0.33%, 3.37%, and 23.9% of patients had osteoporosis (p=0.050). Conclusion: In conclusion, the prevalence of osteoporosis in patients with cirrhosis was found to be 27.7%. Furthermore, patients with a longer duration of disease, low BMI, and with child class C are at greater threat of the occurrence of osteoporosis and require early detection and prompt treatment.","PeriodicalId":34196,"journal":{"name":"International Journal of Endorsing Health Science Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46142232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-21DOI: 10.29052/ijehsr.v10.i3.2022.eoc-00001
S. Urooj, Rafat M. Amin, Zeba Haque
This expression of concern related to the above-mentioned publication highlights the authorship dispute brought to our attention by third parties, which they further transformed into a data authorization claim against the first author (Corresponding Author). It was informed that third parties (Author’s Institution) formed a committee for evaluation, as per their inquiry the manuscript was submitted by the corresponding author without information to the other co-authors. Moreover, the committee has recommended the official retraction of the article due to an authorship claim by a co-supervisor who was not given due credit for his contribution to the work published. The authorship and data authorization issues were raised to the corresponding author and the institution involved for clarifications and investigations. The concern and this note will remain appended to the above-mentioned article, unless the Journal Ethical Committee, Author(s), and Third Party reach a suitable solution to the dispute and proof of misconduct.
{"title":"The Expression of Concern “Evaluation of the antimicrobial potential of partially purified proteins/peptides of Yellow Scorpion Buthus sindicus against Carbapenem-Resistant Acinetobactor baumannii & Pseudomonas aeruginosa” [IJEHSR 9(2) (2021) 238-247]","authors":"S. Urooj, Rafat M. Amin, Zeba Haque","doi":"10.29052/ijehsr.v10.i3.2022.eoc-00001","DOIUrl":"https://doi.org/10.29052/ijehsr.v10.i3.2022.eoc-00001","url":null,"abstract":"This expression of concern related to the above-mentioned publication highlights the authorship dispute brought to our attention by third parties, which they further transformed into a data authorization claim against the first author (Corresponding Author). It was informed that third parties (Author’s Institution) formed a committee for evaluation, as per their inquiry the manuscript was submitted by the corresponding author without information to the other co-authors. Moreover, the committee has recommended the official retraction of the article due to an authorship claim by a co-supervisor who was not given due credit for his contribution to the work published. The authorship and data authorization issues were raised to the corresponding author and the institution involved for clarifications and investigations. The concern and this note will remain appended to the above-mentioned article, unless the Journal Ethical Committee, Author(s), and Third Party reach a suitable solution to the dispute and proof of misconduct.","PeriodicalId":34196,"journal":{"name":"International Journal of Endorsing Health Science Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44928223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Hospital-associated infections are those infections acquired during the patient's stay in a hospital or after the patient has been discharged from the hospital. Healthcare professionals, nurses in particular, are constantly expose to these infections while carrying out their nursing activities. This study aimed to assess the level of knowledge and practice of the standard precautions of infection control among nurses in the selected government hospitals in Sana'a, Yemen. Methods: A cross-sectional study conducted amongst nurses working in five government hospitals in Sana'a City, Yemen. A convenience sample consisting of 232 nurses who work in select hospitals used. The tool used was a self-administered questionnaire. Collected data was analyzed using SPSS version 20. Descriptive statistics used to analyze the study results. Chi-square test, T-test, and One-Way ANOVA test performed and a P-value ?0.05 considered significant. Results: The study revealed that there was a significant statistical difference between nurses' knowledge and practice of standard precautions of infection control (p=0.037). The mean practices percent of nurses practicing safety precautions (53%) was significantly lower than the mean percentage of tested knowledge (81.4%). Less than half of the respondents 106 (45.7%) had a very good knowledge level (>80%), however, only 48 (20.7%) practiced a good level of standard precautions of infection control. Significant statistical differences were found between knowledge and gender (P=0.028) as well as the practice towards work experience and hospital's name (P=0.047, 0.001 respectively). Conclusions: Nurses in the study had good knowledge but the poor practice of standard precautions of infection control. Most of the barriers to using standard precautions of infection control measures were the inadequate supplies of safety devices and the unavailability of infection control protocol in the hospitals.
背景:医院相关性感染是指在患者住院期间或出院后获得的感染。保健专业人员，特别是护士，在进行护理活动时经常接触这些感染。本研究旨在评估也门萨那选定的政府医院护士对感染控制标准预防措施的知识和实践水平。方法:对也门萨那市五所政府医院的护士进行横断面研究。使用了由232名在选定医院工作的护士组成的便利样本。使用的工具是一份自我管理的问卷。收集的数据使用SPSS version 20进行分析。描述性统计用于分析研究结果。经卡方检验、t检验和单因素方差分析检验，p值0.05认为显著。结果:研究结果显示，护士对感染控制标准预防措施的知识与实践存在显著统计学差异(p=0.037)。护士实践安全预防措施的平均百分比(53%)显著低于被测试知识的平均百分比(81.4%)。调查对象106人(45.7%)对感染控制有良好的知识水平(>80%)，但仅有48人(20.7%)对感染控制有良好的标准预防措施。知识与性别(P=0.028)、工作经验与医院名称(P=0.047, 0.001)的差异有统计学意义。结论:本研究护士对感染控制的标准预防措施了解较好，但实践较差。使用感染控制措施的标准预防措施的大多数障碍是安全装置供应不足和医院没有感染控制方案。
{"title":"Knowledge and Practice of Nurses towards Standard Precautions of Infection Control in Government Hospitals of Sana'a City, Yemen","authors":"Gawad M. A. Alwabr, Khalid A. S. Al-Salehi","doi":"10.7324/jhsr.2022.724","DOIUrl":"https://doi.org/10.7324/jhsr.2022.724","url":null,"abstract":"Background: Hospital-associated infections are those infections acquired during the patient's stay in a hospital or after the patient has been discharged from the hospital. Healthcare professionals, nurses in particular, are constantly expose to these infections while carrying out their nursing activities. This study aimed to assess the level of knowledge and practice of the standard precautions of infection control among nurses in the selected government hospitals in Sana'a, Yemen.\u0000Methods: A cross-sectional study conducted amongst nurses working in five government hospitals in Sana'a City, Yemen. A convenience sample consisting of 232 nurses who work in select hospitals used. The tool used was a self-administered questionnaire. Collected data was analyzed using SPSS version 20. Descriptive statistics used to analyze the study results. Chi-square test, T-test, and One-Way ANOVA test performed and a P-value ?0.05 considered significant.\u0000Results: The study revealed that there was a significant statistical difference between nurses' knowledge and practice of standard precautions of infection control (p=0.037). The mean practices percent of nurses practicing safety precautions (53%) was significantly lower than the mean percentage of tested knowledge (81.4%). Less than half of the respondents 106 (45.7%) had a very good knowledge level (>80%), however, only 48 (20.7%) practiced a good level of standard precautions of infection control. Significant statistical differences were found between knowledge and gender (P=0.028) as well as the practice towards work experience and hospital's name (P=0.047, 0.001 respectively).\u0000Conclusions: Nurses in the study had good knowledge but the poor practice of standard precautions of infection control. Most of the barriers to using standard precautions of infection control measures were the inadequate supplies of safety devices and the unavailability of infection control protocol in the hospitals.","PeriodicalId":34196,"journal":{"name":"International Journal of Endorsing Health Science Research","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87112719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Febrile seizure (convulsion) (FC) is a type of seizure which is accompanied by fever, without a history of neurological disease and central nervous system infection. It occurs in approximately 2–5% of children aged between 6 months and 5 years. Complex FC is a type of convulsion which is often accompanied by focal seizures, occurs again within 24 h, and/or lasts longer than 15 min. About 20–25% of patients experience complex FC. Materials and Methods: Our study included 45 patients who applied to Ayd?n State Hospital Pediatric Neurology Clinic between July 2018 and July 2020 and Mersin City Training and Research Hospital between October 2020 and October 2021 with complex febrile seizures. Demographic and laboratory findings of the patients were evaluated retrospectively. Results: Two hundred and seven patients with FC applied to our clinic. Forty-five (21.7%) of these patients had complex FC. Forty-five patients, who were diagnosed with complex FC, were included in the study. The mean age was 16.6 months. LP was performed in 29 (64.4%) patients, EEG was performed in 40 (88.9%) patients. Pleocytosis was detected in three (6.7%) patients, Streptococcus pneumonia was detected in CSF culture in one patient. H1N1 encephalitis was also observed in one of our patients. EEG was taken in all patients within the first 7 days. EEG abnormalities were detected in 5 (11.1%) patients. Conclusion: The presence of postictal neurologic findings was considered as the most important risk factor for CNS infections in our study. It was thought that the detection of epileptiform abnormality in the EEGs of the patients might be relat
{"title":"Evaluation of Clinical, EEG, and Lumbar Puncture Findings of Patients with Complicated Febrile Seizure","authors":"Mahmut Aslan, S. Kırık","doi":"10.7324/jhsr.2022.723","DOIUrl":"https://doi.org/10.7324/jhsr.2022.723","url":null,"abstract":"Introduction: Febrile seizure (convulsion) (FC) is a type of seizure which is accompanied by fever, without a history of neurological disease and central nervous system infection. It occurs in approximately 2–5% of children aged between 6 months and 5 years. Complex FC is a type of convulsion which is often accompanied by focal seizures, occurs again within 24 h, and/or lasts longer than 15 min. About 20–25% of patients experience complex FC.\u0000Materials and Methods: Our study included 45 patients who applied to Ayd?n State Hospital Pediatric Neurology Clinic between July 2018 and July 2020 and Mersin City Training and Research Hospital between October 2020 and October 2021 with complex febrile seizures. Demographic and laboratory findings of the patients were evaluated retrospectively.\u0000Results: Two hundred and seven patients with FC applied to our clinic. Forty-five (21.7%) of these patients had complex FC. Forty-five patients, who were diagnosed with complex FC, were included in the study. The mean age was 16.6 months. LP was performed in 29 (64.4%) patients, EEG was performed in 40 (88.9%) patients. Pleocytosis was detected in three (6.7%) patients, Streptococcus pneumonia was detected in CSF culture in one patient. H1N1 encephalitis was also observed in one of our patients. EEG was taken in all patients within the first 7 days. EEG abnormalities were detected in 5 (11.1%) patients.\u0000Conclusion: The presence of postictal neurologic findings was considered as the most important risk factor for CNS infections in our study. It was thought that the detection of epileptiform abnormality in the EEGs of the patients might be relat","PeriodicalId":34196,"journal":{"name":"International Journal of Endorsing Health Science Research","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89094619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Infantile spasm (West Syndrome) (IS) is an age-dependent epileptic encephalopathy clinic specific to the first two years of life. Infantile spasm is the most known epileptic syndrome of infancy with typical seizures in the form of spasm, psychomotor retardation and hypsarrhythmia on electroencephalography. Typical spasms are in the form of flexor/extensor contractions that last for about 2-5 seconds, which usually symmetrically involves all muscle groups in the body. Material and Method: In this study, the data of patients, who were followed up with the diagnosis of "infantile spasm" in the Pediatric Neurology Clinic of Mersin City Training and Research Hospital between 2020 and 2022, were retrospectively analyzed. Demographic characteristics, clinical, EEG and MRI findings of the patients were analyzed. Results: Eighteen patients were included in the study. Ten (55.5%) of our patients were male and 8 (44.5%) were female. The mean age of patients was ……. years. 11 (61.1%) patients were in the symptomatic group, 5 (27.7%) patients were in the cryptogenic group, and 2 (11.1%) patients were in the idiopathic group. At the time of diagnosis, there was flexor spasm, extensor spasm, mixt spasm, tonic seizure, myoclonic seizure in 5 (27,7%), 4 (22,2%), 4 (22,2%), 3 (16,6%), and 2 (11,1%) patients, respectively. Hypsarrhythmia, suppression-burst pattern, focal epileptic abnormality and generalized epileptic abnormality was observed in 8 (44,4%), 4 (22,2%), 3 (16,6%), and 3 (16,6%) patients, respectively. Of the 14 patients who were first diagnosed, 8 (57.1%) were treated with ACTH, 4 (28.6%) with phenobarbital, 2 (14.3%) with vigabatrin. Conclusion: Infantile spasm is an important age-related encephalopathy with severe neurological sequelae, resistant seizures, and high morbidity and mortality all over the world and in our country. Spasms cause further damage to the central nervous system, which continues to develop. For this reason, a positive contribution can be made in terms of prognosis with early and appropriate treatment.
{"title":"Retrospective Evaluation of Patients with Infantile Spasm Diagnosis","authors":"Mahmut Aslan, Serdal Gungor","doi":"10.7324/jhsr.2022.722","DOIUrl":"https://doi.org/10.7324/jhsr.2022.722","url":null,"abstract":"Introduction: Infantile spasm (West Syndrome) (IS) is an age-dependent epileptic encephalopathy clinic specific to the first two years of life. Infantile spasm is the most known epileptic syndrome of infancy with typical seizures in the form of spasm, psychomotor retardation and hypsarrhythmia on electroencephalography. Typical spasms are in the form of flexor/extensor contractions that last for about 2-5 seconds, which usually symmetrically involves all muscle groups in the body. \u0000Material and Method: In this study, the data of patients, who were followed up with the diagnosis of \"infantile spasm\" in the Pediatric Neurology Clinic of Mersin City Training and Research Hospital between 2020 and 2022, were retrospectively analyzed. Demographic characteristics, clinical, EEG and MRI findings of the patients were analyzed.\u0000Results: Eighteen patients were included in the study. Ten (55.5%) of our patients were male and 8 (44.5%) were female. The mean age of patients was ……. years. 11 (61.1%) patients were in the symptomatic group, 5 (27.7%) patients were in the cryptogenic group, and 2 (11.1%) patients were in the idiopathic group. At the time of diagnosis, there was flexor spasm, extensor spasm, mixt spasm, tonic seizure, myoclonic seizure in 5 (27,7%), 4 (22,2%), 4 (22,2%), 3 (16,6%), and 2 (11,1%) patients, respectively. Hypsarrhythmia, suppression-burst pattern, focal epileptic abnormality and generalized epileptic abnormality was observed in 8 (44,4%), 4 (22,2%), 3 (16,6%), and 3 (16,6%) patients, respectively. Of the 14 patients who were first diagnosed, 8 (57.1%) were treated with ACTH, 4 (28.6%) with phenobarbital, 2 (14.3%) with vigabatrin.\u0000Conclusion: Infantile spasm is an important age-related encephalopathy with severe neurological sequelae, resistant seizures, and high morbidity and mortality all over the world and in our country. Spasms cause further damage to the central nervous system, which continues to develop. For this reason, a positive contribution can be made in terms of prognosis with early and appropriate treatment.","PeriodicalId":34196,"journal":{"name":"International Journal of Endorsing Health Science Research","volume":"451 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82925152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The purpose of this study was to evaluate the effect of adoption of laparoscopic approach for cholecystectomy on liver function tests. This was a retrospective analysis of the data of 242 patients who had undergone laparoscopic cholecystectomy. Liver function tests were not ordered after laparoscopic cholecystectomy in routine surgical practice unless there was some specific reason in the postoperative period to initiate them. Only 14 patients had postoperative liver function tests and 2 had shown a transient rise in levels of enzymes. The rise in hepatic enzymes after laparoscopic cholecystectomy is transient and carries no clinical implications in patients with normal preoperative liver functions.
{"title":"Serum liver enzyme alterations after laparoscopic cholecystectomy – a study.","authors":"Sajad Ahmad Salati","doi":"10.7324/jhsr.2022.725","DOIUrl":"https://doi.org/10.7324/jhsr.2022.725","url":null,"abstract":" The purpose of this study was to evaluate the effect of adoption of laparoscopic approach for cholecystectomy on liver function tests. This was a retrospective analysis of the data of 242 patients who had undergone laparoscopic cholecystectomy. Liver function tests were not ordered after laparoscopic cholecystectomy in routine surgical practice unless there was some specific reason in the postoperative period to initiate them. Only 14 patients had postoperative liver function tests and 2 had shown a transient rise in levels of enzymes. The rise in hepatic enzymes after laparoscopic cholecystectomy is transient and carries no clinical implications in patients with normal preoperative liver functions.","PeriodicalId":34196,"journal":{"name":"International Journal of Endorsing Health Science Research","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74329783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vitorino Modesto Santos, Taciana Arruda Modesto Sugai, Laura Campos Modesto, Julia Campos Modesto
Nail changes detected during the general physical examination can contribute to establishing an initial diagnostic hypothesis and may enhance the awareness of some associated internal disorders. In approximately half of the cases, the changes are detected without being a present complaint. The main causes are dermatological diseases, infections, trauma, drug-related, and genetic entities. Yellow nail syndrome includes lung disorder, pleural effusion, and lymphedema of lower limbs; renal failure, hypothyroidism, malignant tumor, Saint’s triad, and pericarditis are related. The aim of the comments is to emphasize the role of nails evaluation to yield diagnostic clues.
{"title":"Yellow Nail Syndrome and Associated Internal Disturbances","authors":"Vitorino Modesto Santos, Taciana Arruda Modesto Sugai, Laura Campos Modesto, Julia Campos Modesto","doi":"10.7324/jhsr.2022.726","DOIUrl":"https://doi.org/10.7324/jhsr.2022.726","url":null,"abstract":"Nail changes detected during the general physical examination can contribute to establishing an initial diagnostic hypothesis and may enhance the awareness of some associated internal disorders. In approximately half of the cases, the changes are detected without being a present complaint. The main causes are dermatological diseases, infections, trauma, drug-related, and genetic entities. Yellow nail syndrome includes lung disorder, pleural effusion, and lymphedema of lower limbs; renal failure, hypothyroidism, malignant tumor, Saint’s triad, and pericarditis are related. The aim of the comments is to emphasize the role of nails evaluation to yield diagnostic clues.","PeriodicalId":34196,"journal":{"name":"International Journal of Endorsing Health Science Research","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75390630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There are many terms related to authorship. This confuses researchers, especially the most juniors. This narrative review summarizes the definition and criteria of authorship as well as types, number, order, and responsibilities of authors in the medical research. Authorship is classified into three major groups: appropriate, acceptable, and inappropriate. Remedies for authorship misconduct are mentioned.
{"title":"Authorship in medical research: what should authors know?","authors":"Nesrine S Farrag, A. El-Gilany","doi":"10.7324/jhsr.2022.721","DOIUrl":"https://doi.org/10.7324/jhsr.2022.721","url":null,"abstract":"There are many terms related to authorship. This confuses researchers, especially the most juniors. This narrative review summarizes the definition and criteria of authorship as well as types, number, order, and responsibilities of authors in the medical research. Authorship is classified into three major groups: appropriate, acceptable, and inappropriate. Remedies for authorship misconduct are mentioned.","PeriodicalId":34196,"journal":{"name":"International Journal of Endorsing Health Science Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89947362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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