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A Case Report of a Rare Huge Ureteral Fibroepithelial Polyp: Challenges and Clinical Management 罕见巨大输尿管纤维上皮性息肉一例报告:挑战与临床处理
Pub Date : 2022-10-11 DOI: 10.18502/crcp.v7i2.10822
A. Rezayat, A. Yarahmadi, Atena Aghaee, Farid Zeynali, Salman Soltani
Ureteral  fibroepithelial  polyps  (UFPs)  are  rare  abnormality  that  may  cause  ureteral obstruction.  Herein,  we  report  a  35-  year-  old  woman  with  flank  pain,  dysuria, frequency and transient total gross hematuria. A mass in the right ureter was reported on imaging and in endoscopic evaluation, small polypoid mass protruding from the right ureteral orifice in the bladder, and a huge ureteral mass originating from proximal ureter was observed. A right subcostal flank incision was done, a huge polypoid mass with a segment of ureteral was excised, and end-to-end anastomosis of the ureter was done. Histopathological examination showed a UFP without malignancy.
输尿管纤维上皮息肉(UFPs)是一种罕见的异常,可引起输尿管梗阻。在此,我们报告一位35岁女性,有腹痛、排尿困难、尿频及短暂性肉眼血尿。影像学和内镜评估中报告了右输尿管的肿块,从膀胱的右输尿管口突出的小息肉状肿块,以及从输尿管近端产生的巨大输尿管肿块。右侧肋下侧面切开,切除一个巨大的息肉状肿块和一段输尿管,并对输尿管进行端对端吻合。组织病理学检查显示UFP无恶性肿瘤。
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引用次数: 0
Benign Metastasizing Leiomyoma of The Lung: A Case Report 良性转移性肺平滑肌瘤1例报告
Pub Date : 2022-10-11 DOI: 10.18502/crcp.v7i2.10825
M. Pazoki, E. Nazar, B. Jahanbin
Introduction: Benign metastasizing leiomyoma  of the lung which is categorized by the growth of uterine leiomyoma in the lung is an extremely exceptional disease. Case presentation: We report a 39-year-old woman who had a previous history of uterine leiomyoma. Chest computed tomography (CT) scan exhibited round nodules well-defined margins in both lungs. Thoracoscopic partial resection of the lung was done. Pathological and immunohistochemical examination showed that neoplastic tissue composed of spindle-shaped smooth muscle cells, compatible with uterine leiomyoma. Thus, these tumors can be reflected to be lung metastases from a uterine leiomyoma (benign metastasizing leiomyoma). Conclusion: It is an uncommon condition but it would be careful in women of reproductive age with a past medical history of uterine leiomyoma, who existing with pulmonary nodules.
引言:肺良性转移性平滑肌瘤是一种极其特殊的疾病,按肺中子宫肌瘤的生长分类。病例介绍:我们报告一名39岁女性,既往有子宫平滑肌瘤病史。胸部计算机断层扫描(CT)显示两肺的圆形结节边界清晰。行胸腔镜肺部分切除术。病理和免疫组织化学检查显示,肿瘤组织由梭形平滑肌细胞组成,与子宫平滑肌瘤相容。因此,这些肿瘤可以反映为子宫平滑肌瘤的肺转移(良性转移性平滑肌瘤)。结论:这是一种不常见的情况,但对于有子宫平滑肌瘤病史的育龄妇女,如有肺结节,则应小心。
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引用次数: 0
Congenital Insensitivity to Pain with Anhidrosis (CIPA) Syndrome; A Rare Genetic Disorder Case Story 先天性无汗性疼痛不敏感综合征;一个罕见的遗传疾病病例故事
Pub Date : 2022-10-11 DOI: 10.18502/crcp.v7i2.10827
Zahra Nafei, Marjan Jafari
Congenital insensitivity to pain with anhidrosis (CIPA) is the subtype four of hereditary sensory and autonomic neuropathy (HASN IV), caused by a defect in the NTRK1 gene and presenting early in life. We report a ten-year-old boy with gait problems and an inability to put weight on his feet. Four days before the visit, a trauma entered his right knee during a football match. He had swelling and erythema in his right knee and multiple scars on his torso and limbs. Magnetic resonance imaging (MRI) offered osteomyelitis and soft tissue periosteal abscess. The patient underwent an operation, and based on the pathology results, myositis ossificans (MO) was reported. Moreover, he was treated with antibiotics and supportive measures and was discharged with partial recovery. According to our knowledge, this is the first report of MO due to recurrent trauma in children with CIPA syndrome.
先天性对疼痛不敏感伴无汗症(CIPA)是遗传性感觉和自主神经病变(HASN IV)的第四亚型,由NTRK1基因缺陷引起,并在生命早期出现。我们报告了一个十岁的男孩,他有步态问题,无法给脚增加重量。在访问的四天前,他的右膝在一场足球比赛中受伤。他的右膝有肿胀和红斑,躯干和四肢有多处疤痕。磁共振成像(MRI)显示骨髓炎和软组织骨膜脓肿。患者接受了手术,根据病理结果,报告了骨化性肌炎(MO)。此外,他接受了抗生素和支持措施的治疗,出院后部分康复。据我们所知,这是CIPA综合征儿童因反复创伤而出现MO的首次报告。
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引用次数: 0
Respiratory Distress Due to Giant Pulmonary Hydatid Cyst 巨大肺包虫囊肿所致呼吸窘迫
Pub Date : 2022-10-11 DOI: 10.18502/crcp.v7i2.10826
R. Ershadi
Pulmonary echinococcosis most frequently occurs in the right and both lower lobes. Children are more likely to develop pulmonary rather than hepatic echinococcal cysts.  Some evidence suggests that echinococcal cysts develop more rapidly in the lungs of children than those of adults, which may explain the more common appearance of pulmonary cysts in children. Younger patients have larger cysts owing to their greater tissue elasticity. Large pulmonary hydatid cysts are critical because they pose a higher risk of rupture. Herein, we present an eight-year-old girl presented with severe respiratory distress due to giant hydatid cyst of right lung with shift of the mediastinum at left. The lesion displaced the trachea at left. The patient was successfully treated by parenchymal-saving operation. In conclusion, Giant hydatid lung cysts represent a distinct clinical entity most frequently encountered in children and adolescents with more serious symptoms. Although non-complicated giant hydatid cysts have a good prognosis regardless of their size and can be safely treated by parenchyma-preserving surgery.
肺棘球蚴病最常见于右肺和双肺下叶。儿童更容易患肺包虫病而不是肝包虫病。一些证据表明,棘球蚴囊肿在儿童肺部的发展速度比成人更快,这可能解释了儿童肺囊肿更常见的现象。年轻患者的囊肿较大,因为他们的组织弹性较大。较大的肺包虫囊肿是很重要的,因为它们有较高的破裂风险。在此,我们报告一名八岁女孩,因右肺巨大包虫病并左侧纵隔移位而出现严重呼吸窘迫。病变使左侧气管移位。病人经保实质手术治疗成功。总之,巨大包虫肺囊肿是一种独特的临床实体,最常见于儿童和青少年,症状更严重。尽管无并发症的巨大包虫囊肿不论大小,预后良好,且可通过保实质手术安全治疗。
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引用次数: 0
Hydrops Fetalis and Mirror Syndrome Secondary to Rh-D Alloimmunization, Associated With Oligohydramnious: A Case Report Rh-D异常免疫继发的胎儿水肿和镜像综合征伴羊水过少1例报告
Pub Date : 2022-10-03 DOI: 10.18502/crcp.v7i2.10781
F. Rahimi‐Sharbaf, M. Shirazi, Maasoumeh Saleh, F. Golshahi
One of the most common causes of fetal anemia is red cell alloimmunization. The most common routes of maternal sensitization are via blood transfusion or fetomaternal hemorrhage. Antibodies can cross the placenta during pregnancies in alloimmunized women and, if the fetus is positive for these specific erythrocyte surface antigens, result in hemolysis of fetal erythrocytes and anemia. This in turn, can lead to potentially disastrous consequence for the fetus, such as Hydrops Fetalis (HF), a high-output cardiac failure syndrome. The standard treatment in fetuses with anemia is intrauterine transfusion (IUT). Mirror Syndrome (MS) is a rare condition in pregnancy, in which maternal edema in pregnancy is seen in association with severe fetal and/or placental hydrops. The pathogenesis, although not well established, mimics trophoblastic damage and maternal vascular endothelial dysfunction, as is also observed in preeclampsia, and hence, the two conditions may have a similar clinical presentation [1]. The clinical manifestations of this disease are complex. It is easily underdiagnosed and timely intervention is needed to prevent fetal and maternal morbidity. MS can be reversible when the underlying factors are identified and modified [2, 3]. If correction of the underlying fetal abnormality is not possible, the consensual treatment is to deliver the hydropic fetus and placenta, with improvement of the maternal condition shortly thereafter. We report a case of HF and MS secondary to Rh-D alloimmunization that did not respond to IUT.
胎儿贫血最常见的原因之一是红细胞异体免疫。最常见的产妇致敏途径是输血或母婴出血。在接受同种异体免疫的妇女怀孕期间,抗体可以穿过胎盘,如果胎儿对这些特异性红细胞表面抗原呈阳性,就会导致胎儿红细胞溶血和贫血。反过来,这可能会对胎儿造成潜在的灾难性后果,如胎儿水肿(HF),一种高输出量心力衰竭综合征。胎儿贫血的标准治疗是宫内输血(IUT)。镜像综合征(MS)是一种罕见的妊娠情况,在妊娠中,母体水肿与严重的胎儿和/或胎盘水肿有关。其发病机制虽然尚未完全确定,但与滋养细胞损伤和母体血管内皮功能障碍相似,这在子痫前期也有观察到,因此,这两种情况可能具有相似的临床表现。本病临床表现复杂。它很容易被误诊,需要及时干预以防止胎儿和孕产妇发病。当潜在因素被识别和修改后,多发性硬化症是可逆的[2,3]。如果不可能纠正潜在的胎儿异常,双方同意的治疗是分娩积水的胎儿和胎盘,此后不久母体状况得到改善。我们报告一例继发于Rh-D异体免疫的HF和MS对IUT没有反应。
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引用次数: 0
Bilateral Simultaneous Atypical Femoral Fracture: A Case Report 双侧同时发生非典型股骨骨折1例
Pub Date : 2022-10-03 DOI: 10.18502/crcp.v7i2.10785
S. Ghaffari, Mehran Razavipour, Soroosh Fateh
We report a rare case of bilateral subtrochanteric femoral fracture related to prolonged treatment with Alendronate. Introduction: Bisphosphonates are the most common drugs used for treatment of osteoporosis and prevention of the risk of osteoporosis-related fractures. Atypical femoral fractures (AFF) have been reported in patients who have been on long term treatment with bisphosphonates especially Alendronate.  Case Report: our case was a 68- year- old woman who sustained bilateral subtrochanteric femoral fracture after a simple falling down. She had a past medical history of osteoporosis and had been on treatment with alendronate for 5 years. Radiographs showed bilateral fractures in femur subtrochanteric area. We decided to use double plating technique and we used angled blade plate and locking plate (LCP). Alendronate was discontinued and Teriparatide was started. Discussion: Careful evaluation of hip or thigh pain in patients who are on prolonged courses of bisphosphonates is essential. Our method of fixation with double plating can be used in patients with poor bone quality.
我们报告了一例罕见的双侧股骨转子下骨折,与阿仑膦酸盐的长期治疗有关。简介:双膦酸盐是治疗骨质疏松症和预防骨质疏松症相关骨折风险的最常见药物。据报道,长期使用双膦酸盐(尤其是阿仑膦酸盐)治疗的患者出现非典型股骨骨折(AFF)。病例报告:我们的病例是一位68岁的女性,她在一次简单的摔倒后遭受了双侧股骨粗隆下骨折。她有骨质疏松症病史,已接受阿仑膦酸盐治疗5年。X线片显示股骨转子下区双侧骨折。我们决定使用双镀层技术,并使用倾斜刀片板和锁定板(LCP)。阿仑膦酸盐停用,特立帕肽开始使用。讨论:对于长期服用双磷酸盐的患者,仔细评估髋关节或大腿疼痛是至关重要的。我们的双钢板固定方法可用于骨质量差的患者。
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引用次数: 1
Herpes Zoster Ophthalmicus and Encephalitis Following Botulinum Toxin Type A Injection for Blepharospasm: A Case Report 注射A型肉毒杆菌毒素治疗眼睑痉挛致带状疱疹性眼炎和脑炎1例
Pub Date : 2022-10-03 DOI: 10.18502/crcp.v7i2.10782
Ghasem Farahmand, Hanna Magrouni, Vahideh Zolfaghari, Sina Gharehjeh, Sakineh Ranji-Burachaloo
A 68- year – old male was admitted to ER of Referral Imam Khomeini hospital with abrupt commence of fever accompanied with debilitating non-radiating headache, photophobia, ataxia and cluster of confluent vesicles on right side of forehead with swelling of right eyelid. All his symptoms started after receiving Botulinum injection on the same week before admission and he had never had similar manifestations beforehand. His medical history was remarkable for hyperlipidemia, hypertension and right side Blepharospasm for which he received Botulinum injection every 6 months. He was on medication for the rest of his medical problems. He was not on any immunosuppressive medication and did not suffer from any disease weakening the immune system. His family history was unremarkable for any similar problems. In medical exam, he was ill but not toxic, his vital signs were blood pressure of 135/80 mmHg, heart rate of 76, respiratory rate of 17 and oral temperature of 38.5Ĉ. He had vesicles on his right forehead. Heart sounds were regular without murmur. Lungs were clear. Abdominal examinations were inconspicuous. In neurological examinations, he was confused and disoriented to time and place. Cranial nerves were without any pathological findings except for positive Marcus Gunn of affected side and blurring of right optic disk margin. No muscle atrophy was seen. Muscle force showed no weakness. He was ataxic. Sensory examination was normal. Reflexes were checked and were within normal limits and symmetric. Computer tomography (CT) scan of head was unremarkable and his MRI scan did not reveal any information compatible with his symptoms. Due to the sudden onset of fever with headache and confusion, encephalitis was suspected and empirical therapy with antibiotics was started and LP was performed which indicated pleocytosis in CSF. According to the vesicles on the skin and with suspicion of Varicella encephalitis, PCR was sent for diagnosis of VZV. Subsequently, his condition got dramatically better and symptoms diminished after acyclovir was started.
一名68岁的男性因突然发烧并伴有衰弱性非辐射性头痛、畏光、共济失调和前额右侧聚集性小泡并伴有右眼睑肿胀而住进伊玛目霍梅尼医院急诊室。他的所有症状都是在入院前同一周注射肉毒杆菌素后开始的,此前他从未有过类似的表现。他的病史为高脂血症、高血压和右侧眼睑痉挛,每6个月注射一次肉毒杆菌素。他其余的医疗问题都在接受药物治疗。他没有服用任何免疫抑制药物,也没有患上任何削弱免疫系统的疾病。他的家族史没有任何类似的问题。在体检中,他生病了,但没有中毒,他的生命体征是血压135/80毫米汞柱,心率76,呼吸频率17,口腔温度38.5Ĉ。他的右前额有小泡。心音正常,无杂音。肺部通畅。腹部检查不明显。在神经系统检查中,他对时间和地点感到困惑和迷失方向。除患侧Marcus Gunn阳性和右侧视盘边缘模糊外,颅神经未见任何病理学表现。未发现肌肉萎缩。肌肉力量没有减弱。他患有共济失调。感官检查正常。检查了反射,反射在正常范围内且对称。头部的计算机断层扫描(CT)并不明显,他的MRI扫描也没有显示任何与他的症状相符的信息。由于突然发烧并伴有头痛和意识模糊,怀疑为脑炎,开始了抗生素的经验性治疗,并进行了LP,这表明CSF中存在白细胞增多症。根据皮肤上的小泡,并怀疑是水痘脑炎,PCR被用于诊断VZV。随后,他的病情明显好转,服用阿昔洛韦后症状减轻。
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引用次数: 2
A Rare Entity of Gall Bladder: Ectopic Liver (Choristoma) 一种罕见的胆囊疾病:异位肝(脉络瘤)
Pub Date : 2022-10-03 DOI: 10.18502/crcp.v7i2.10784
M. Yıldırım, A. Argon, A. Cekic
Ectopic liver is defined as the presence of normally organized liver tissue outside its normal location. It is frequently found in the gallbladder. Ectopic liver is normally asymptomatic and only discovered incidentally. We report a case of 51- year- old woman with ectopic liver and we also review the characterization of this rare entity .This report adds another case to the very rarely reported ectopic liver located in the gallbladder.
异位肝被定义为在其正常位置之外存在正常组织的肝组织。常见于胆囊。异位肝通常无症状,只是偶然发现。我们报告一例51岁女性异位肝,并回顾此罕见病例的特征。此报告为罕见的胆囊异位肝增加了另一例。
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引用次数: 0
Neonatal Clinical Early-onset Sepsis and COVID-19: A Case Presentation 新生儿临床早发脓毒症和COVID-19:一例报告
Pub Date : 2022-10-03 DOI: 10.18502/crcp.v7i2.10783
M. Saeedi, Razieh Sangsari, K. Mirnia
Introduction: After the Ministry of the health of Iran officially announced widespread of COVID-19 on 19 February 2020, our attention focused on novel coronavirus. In our case, a2-day- old neonate shows symptoms of sepsis. The main presentation was hypothermia and desaturation. The mother was COVID-19 positive with an active cough. The PCR of the neonate was negative. We don’t claim that the neonate is affected by COVID-19, but this may be an atypical form of sepsis in neonates with positive mothers following COVID-19.  Case presentation: A2-day- old female neonate with a gestational age of 40 weeks and a birth weight of 2370 grams was born via the cesarean route from a mother who was a 34-year-old primigravida woman without any history of disease during pregnancy. Two days before delivery, the mother had malaise and dry cough. She was diagnosed as a COVID-19 positive case based on RT-PCR after delivery. On the second day after birth, the parents brought the baby to the emergency room of the children’s medical center hospital with complaints of poor feeding, poor sucking and decreased urination. Physical examination revealed the following signs; hypothermia; T=36℃, diminished primitive reflexes, hypotonia, and oxygen desaturation until 85% without respiratory distress that increased to 98% with oxy hood. We admitted and treated her early-onset sepsis and discharged in excellent condition. Conclusion: Early-onset sepsis as defined is a clinical state that is transferred from mother. The presentations in our case maybe a new form of clinical sepsis following a mother with COVID-19. We don’t claim that our case is COVID-19 positive but in neonates with affected mother’s insidious symptoms should be in concern.
导言:2020年2月19日,伊朗卫生部正式宣布COVID-19大范围传播后,我们的注意力集中在新型冠状病毒上。在我们的病例中,2天大的新生儿表现出败血症的症状。主要表现为体温过低和去饱和。母亲呈COVID-19阳性,咳嗽活跃。新生儿PCR结果为阴性。我们并不是说新生儿受到了COVID-19的影响,但这可能是COVID-19阳性母亲的新生儿的非典型败血症。病例介绍:产妇为34岁初产妇,妊娠期无任何疾病史,经剖宫产产下一名2天大、胎龄40周、出生体重2370克的女婴。临产前两天,产妇身体不适,并伴有干咳。她在分娩后通过RT-PCR被诊断为新冠病毒阳性。出生后第二天,父母带着婴儿来到儿童医疗中心医院急诊室,主诉喂养不良、吸吮不良、排尿减少。体格检查发现以下征象:体温过低;T=36℃,原始反射减弱,低张力,氧饱和度下降至85%,无呼吸窘迫,呼吸窘迫增加至98%。我们收治并治疗了她的早发败血症,出院时情况良好。结论:早发性脓毒症是一种由母体转移而来的临床状态。在我们的病例中,表现可能是一种新的临床败血症,在一位患有COVID-19的母亲之后。我们并不是说我们的病例是COVID-19阳性,但应该关注患有受感染母亲潜伏症状的新生儿。
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引用次数: 0
Concomitant Bilateral Papillary Thyroid Carcinoma and Parathyroid Adenoma 伴发双侧甲状腺乳头状癌和甲状旁腺腺瘤
Pub Date : 2022-06-14 DOI: 10.18502/crcp.v7i1.9631
R. Hajebi, E. Nazar, S. Mashhadi
Thyroid malignant neoplasms are the most prevalent cancer of the endocrine system, and their concurrence with parathyroid neoplasms is extremely rare. We report a 69-year-old woman presenting with hypercalcemia and thyroid nodule, which histologic examination revealed bilateral papillary thyroid carcinoma with different variants coincident with parathyroid adenoma. Awareness of concomitant parathyroid and thyroid diseases may help manage patients with hypercalcemia history. So, we recommended a preoperative calcium check in a patient with a thyroid nodule.
甲状腺恶性肿瘤是内分泌系统中最常见的癌症,与甲状旁腺肿瘤并存的情况极为罕见。我们报告了一名69岁的女性,其表现为高钙血症和甲状腺结节,其组织学检查显示双侧甲状腺乳头状癌具有与甲状旁腺腺瘤一致的不同变体。对伴发甲状旁腺和甲状腺疾病的认识可能有助于管理有高钙血症病史的患者。因此,我们建议对甲状腺结节患者进行术前钙检查。
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引用次数: 0
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Case Reports in Clinical Practice
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