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Primary Sclerosing Cholangitis Pruritus Treated with Plasmapheresis 血浆置换治疗原发性硬化性胆管炎瘙痒
Pub Date : 2023-04-04 DOI: 10.1055/s-0043-1761510
Katharine Tippins, Oyewale O. Shiyanbola, W. N. Rose
Abstract Evidence regarding the efficacy of plasmapheresis for pruritus due to hepatobiliary disease is sparse. The mechanism of pruritus in this context is poorly understood. Some candidates for the offending agents are bile salts and histamine. Primary sclerosing cholangitis is one such disease and appears to have an autoimmune component. The rationale for plasmapheresis for patients who are refractory to medical therapy has some plausibility because the nonspecific nature of plasmapheresis may significantly decrease one or more of the offending substances in the patient's plasma. We share our experience of a patient with pruritus due to primary sclerosing cholangitis who benefited from plasmapheresis.
关于血浆置换治疗肝胆疾病所致瘙痒的疗效的证据很少。在这种情况下,瘙痒的机制尚不清楚。一些候选的致病因子是胆盐和组胺。原发性硬化性胆管炎就是这样一种疾病,似乎有自身免疫成分。对药物治疗难治性患者进行血浆置换的理由有一定道理,因为血浆置换的非特异性可能会显著减少患者血浆中的一种或多种有害物质。我们分享我们的经验,患者瘙痒由于原发性硬化性胆管炎谁受益于血浆置换。
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引用次数: 0
Difficult Bronchoscopy and Foreign Body Removal: Our Experience 困难的支气管镜检查和异物清除:我们的经验
Pub Date : 2023-04-04 DOI: 10.1055/s-0043-1764365
P. S., N. Rb, G. K., Karthika Sr, R. S
Abstract Background  Foreign body in the airway is the most life-threatening situation. Most foreign bodies present as acute emergency and can be removed by endoscopy/bronchoscopy, while a few causes complication of a retained foreign body which requires emergency tracheostomy to secure airway followed by foreign body removal. Case Presentation  We report our experience in the management of three children who required tracheostomy through which bronchoscope was introduced and foreign body removed. All patients with unrecognized retained foreign body presented with respiratory distress with desaturation. Imaging was suggestive of atelectasis. After foreign body removal patients recovered well and decannulated by day 5. Subglottis is the narrowest part of pediatric airway. As these foreign bodies were vegetative they are hygroscopic in nature and hence would not be able to remove the foreign body by bronchoscopic guidance. Hence, tracheostomy was done to provide access followed by bronchoscopic removal. Conclusion  Aspirated foreign body present challenges to the ear, nose, and throat surgeon. Newer techniques enable removal of foreign body easier. Tracheostomy combined with bronchoscopy can be a life-saving and easy to perform procedure which involves removal of foreign body at the same time.
摘要背景呼吸道异物是最危及生命的情况。大多数异物是急性急诊,可通过内窥镜/支气管镜清除,而少数异物会引起并发症,需要紧急气管切开术以确保气道安全,然后取出异物。我们报告我们的经验,在处理三个儿童需要气管切开术,通过支气管镜和异物取出。所有未识别的异物残留患者均表现为呼吸窘迫伴去饱和。影像学提示肺不张。异物取出后患者恢复良好,第5天脱管。声门下是小儿气道最狭窄的部分。由于这些异物是植物性的,它们本质上是吸湿的,因此不能通过支气管镜引导去除异物。因此,气管切开术提供通道,然后支气管镜切除。结论吸入性异物是耳鼻喉外科医师面临的挑战。较新的技术使清除异物更容易。气管切开术联合支气管镜检查可以挽救生命,并且易于操作,同时可以清除异物。
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引用次数: 0
Mitochondrial Disease Masquerading as Recurrent Encephalopathy 线粒体疾病伪装成复发性脑病
Pub Date : 2023-04-04 DOI: 10.1055/s-0043-1761616
Rajalaxmi Satapathy, Pragateshnu Das
Abstract A young male who was a diabetic presented with gradually progressive hearing loss, recurrent episodic behavioral abnormality, easy fatigability, proximal weakness, and seizures. The patient was evaluated in detail to find out the etiology of encephalitis. The serum autoimmune encephalitis panel was negative. On magnetic resonance imaging of the Brain, there was temporoparietal T2 and fluid-attenuated inversion recovery hyperintensity. In the magnetic resonance spectroscopy study, a lactate peak was found. So, the patient was evaluated for mitochondrial illness mitochondrial encephalopathy lactic acidosis with stroke-like symptoms) and it was confirmed by a genetic study. This case illustrates that though it is a rare disease, always a strong clinical index of suspicion is required for the diagnosis of mitochondrial disorders in case of multisystem involvement so that diagnosis would not be missed.
摘要一位年轻男性糖尿病患者表现为逐渐进行性听力丧失,反复发作性行为异常,易疲劳,近端无力和癫痫发作。对患者进行了详细的评估,以查明脑炎的病因。血清自身免疫性脑炎检查结果为阴性。脑磁共振成像显示颞顶叶T2和液体衰减反转恢复高信号。在磁共振波谱研究中,发现一个乳酸峰。因此,患者被评估为线粒体疾病(线粒体脑病(有卒中样症状的乳酸性酸中毒),并通过基因研究得到证实。本病例说明,虽然是一种罕见的疾病,但在累及多系统的情况下,对线粒体疾病的诊断总是需要强烈的临床怀疑指标,以免漏诊。
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引用次数: 0
“Clinicoradiological Score – Valuable Tool to Assess the Risk of Strangulated Small Bowel Obstruction in Tertiary Care Center” “临床放射学评分-评估三级保健中心绞窄性小肠阻塞风险的宝贵工具”
Pub Date : 2023-04-04 DOI: 10.1055/s-0043-1761416
Gunasekaran Monisha, M. S, H. Ranganath
Abstract Background  Small bowel obstruction accounts for about 3% of the emergency laparotomies, hence there is a need for early recognition of the risk associated with strangulated small bowel obstruction. However, there is no single reliable tool for evaluating the bowel strangulation risk precisely and quickly, hence we sought to assess the specificity and sensitivity of a scoring system named “Clinicoradiological score” as a tool to assess the risk of strangulated small bowel obstruction in tertiary care center for early intervention. Methods  The study was an observational study conducted on 50 patients with clinical symptoms of small intestinal obstruction, diagnosed by CT and admitted in-patient basis at the general surgery department in the hospitals attached to Bangalore Medical College and Research Institute, Bengaluru from November 2017 to May 2019. In this scoring system, one point was given to each factor which includes pain duration (4 or more days), guarding, leucocyte count at least 10 ×10 9 /L, C-reactive protein 75 mg/L or more, free fluid at least 500 mL (CT criteria), reduced wall contrast enhancement (CT criteria) leading to a maximum score of 6. Statistics  Based on standard treatment outcome, patients were grouped into three categories (conservative management, laparotomy without resection and anastomosis, and laparotomy with resection and anastomosis). Data was analyzed by descriptive statistics. The risk factors were compared between three patient groups and Chi-square test used for hypothesis testing. Sensitivity and specificity were evaluated for accuracy of score. Results  Out of the six factors of Clinicoradiological score, five factors were found to be predictors ( p -value <0.01), while history of pain more than 3 days did not have a significant p -value. In our study all 18 patients with score more than 3 had gangrenous changes and underwent resection. The p -value of the score was found to be significant. Conclusion  Clinicoradiological score has been proved to be a valuable tool in predicting the risk of strangulated small bowel obstruction and ascertained the need for subsequent intestinal resection.
背景小肠梗阻约占急诊剖腹手术的3%,因此需要早期认识绞窄性小肠梗阻的相关风险。然而,目前还没有一种可靠的工具可以准确、快速地评估肠绞窄风险,因此,我们试图评估一种名为“临床放射学评分”的评分系统的特异性和敏感性,作为评估三级保健中心绞窄性小肠梗阻风险的工具,以进行早期干预。方法对2017年11月至2019年5月在班加罗尔医学院附属医院普通外科住院的50例经CT诊断有小肠梗阻临床症状的患者进行观察性研究。在这个评分系统中,每个因素都给1分,包括疼痛持续时间(4天或更长)、保护、白细胞计数至少10 ×10 9 /L、c反应蛋白75 mg/L或更多、游离液至少500 mL (CT标准)、壁增强减弱(CT标准),最高得分为6分。根据标准治疗结果,将患者分为保守治疗、开腹不切除吻合、开腹切除吻合3组。数据采用描述性统计进行分析。比较三组患者的危险因素,采用卡方检验进行假设检验。对评分的准确性进行敏感性和特异性评估。结果在临床放射学评分的6个因素中,有5个因素是预测因子(p值<0.01),而疼痛史大于3 d无显著p值。在我们的研究中,所有18例评分超过3分的患者都发生了坏疽性改变并进行了切除。发现得分的p值具有显著性。结论临床放射学评分是预测绞窄性小肠梗阻风险和确定后续肠切除术必要性的重要工具。
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引用次数: 1
Knotted Stent—Emphasizing the Need of Radiology Assistance in Urology 结扎支架——强调泌尿外科放射辅助的需要
Pub Date : 2023-04-04 DOI: 10.1055/s-0043-1764364
S. P. Dhangar
Abstract Ureteral double-J stents have become a part and parcel in contemporary urologic practice. As the use of stents is increasing, the complications are also increasing. Knot formation in the double-J stent is rare phenomenon. Twenty-seven cases have been reported till now. This case would be the 28th case to be reported, in a young male with solitary left kidney and who was on regular periodic stent substitution.
输尿管双j型支架已成为当代泌尿外科的重要组成部分。随着支架使用的增加,并发症也在增加。双j型支架中结的形成是罕见的现象。截至目前已报告27例。该病例将是第28例报告的病例,在一个年轻的男性与孤立的左肾,谁是定期支架置换。
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引用次数: 0
Clinical and Radiological Results of Minimally Invasive Two-Hole Dynamic Hip Screw Fixation of Stable Intertrochanteric Fractures: A Prospective Study of 50 Patients 微创双孔动力髋螺钉固定稳定转子间骨折的临床和影像学结果:一项50例患者的前瞻性研究
Pub Date : 2023-04-04 DOI: 10.1055/s-0043-1761618
F. A. Dar, Zaffar Iqbal, A. H. Lone, N. Ali
Abstract Background  Intertrochanteric fractures are fractures of elderly population and are known for morbidity and mortality. Early stabilization with minimal surgical trauma is important for early mobilization to prevent recumbence-related complications. Methods  This prospective study was conducted on 50 stable intertrochanteric fractures that were managed by fixation with a small two-hole dynamic hip screw –(DHS) side plate using a minimally invasive technique. The surgical time, intraoperative blood loss, length of the skin incision, duration of hospital stay, time to full weight bearing and fracture union, and complications were recorded. Results  The mean age of the patients was 60.2 years with 64% belonging to male sex. The mean operative time, average blood loss, and mean incision length were 35.6 minutes, 68.4 mL, and 3.7 cm, respectively. Time to bone healing ranged from 10 to 16 weeks (mean 13 weeks). Two patients had hip screw backout but that did not interfere with failure of fixation. Conclusion  Stabilization of stable intertrochanteric fractures with two-hole DHS using minimally invasive approach is a viable option with negligible complication rate related to failure of small DHS side plate.
摘要背景:股骨粗隆间骨折是老年人骨折,发病率和死亡率高。早期稳定与最小的手术创伤是重要的早期活动,以防止仰卧相关的并发症。方法对50例稳定的股骨粗隆间骨折进行前瞻性研究,这些骨折均采用微创技术用小的双孔动态髋螺钉-侧板固定。记录手术时间、术中出血量、皮肤切口长度、住院时间、完全负重时间、骨折愈合时间及并发症。结果患者平均年龄60.2岁,男性占64%。平均手术时间35.6分钟,平均出血量68.4 mL,平均切口长度3.7 cm。骨愈合时间为10 ~ 16周(平均13周)。2例患者髋螺钉退出,但不影响固定失败。结论微创入路固定稳定型转子间骨折是一种可行的方法,且小DHS侧板失效并发症发生率可忽略不计。
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引用次数: 0
A Case of Primary EAC Cholesteatoma Extending into Antrum with Normal Middle Ear 原发性EAC胆脂瘤延伸至正常中耳鼻窦1例
Pub Date : 2023-04-04 DOI: 10.1055/s-0043-1761458
S. Shrivastava, Rishita Kalra, Somyagupta Somyagupta, V. Pathak, P. Nayak, Stuti Shukla
Abstract Introduction  A cholesteatoma is a three-dimensional sac lined by keratinized squamous epithelium containing desquamated keratinized epithelial cell which secretes enzymes that have the tendency to expand and erode the bony structure underlying it and cause intracranial and extracranial complications. This cystic mass is in an abnormal location such as the middle ear, the petrous apex, or the external auditory canal (EAC). It is mostly found in the middle ear and rarely in the EAC. Here we have reported a rare case of unilateral primary EAC cholesteatoma with mild hearing loss in a middle-aged male. Case Report  We have reported a case of a 34-year-old male with complaints of right-sided ear discharge and right-sided decreased hearing for the last 5 to 6 years. On examination, right ear EAC was found to be dry, and a sac was observed in posterior wall extending to mastoid present with clear attic, and intact retracted tympanic membrane that was then followed by radiological evaluation to establish the diagnosis of EAC cholesteatoma. This was surgically treated and ear was cleared of all disease. Patient's symptoms improved postoperatively. Conclusion  Primary EAC cholesteatoma with disease-free middle ear is a rare finding and there is very less definitive literature available on the pathogenesis of the same.
胆脂瘤是一种由角质化的鳞状上皮内衬的三维囊,其中含有脱皮的角质化上皮细胞,其分泌的酶具有扩张和侵蚀其底层骨结构的倾向,并引起颅内和颅外并发症。囊性肿块位于异常位置,如中耳、岩尖或外耳道。它主要发生在中耳,很少发生在EAC。我们在此报告一例罕见的单侧原发性EAC胆脂瘤合并轻度听力损失的中年男性病例。病例报告我们报告了一例34岁男性,在过去的5至6年里,他的主诉是右耳分泌物和右侧听力下降。检查发现右耳EAC干燥,后壁可见囊囊延伸至乳突,有清晰的上盖,鼓膜完整缩回,影像学检查确定EAC胆脂瘤的诊断。手术治疗后,所有的疾病都被清除了。患者术后症状好转。结论原发性EAC胆脂瘤合并无病中耳是一种罕见的发现,其发病机制的明确文献很少。
{"title":"A Case of Primary EAC Cholesteatoma Extending into Antrum with Normal Middle Ear","authors":"S. Shrivastava, Rishita Kalra, Somyagupta Somyagupta, V. Pathak, P. Nayak, Stuti Shukla","doi":"10.1055/s-0043-1761458","DOIUrl":"https://doi.org/10.1055/s-0043-1761458","url":null,"abstract":"Abstract Introduction  A cholesteatoma is a three-dimensional sac lined by keratinized squamous epithelium containing desquamated keratinized epithelial cell which secretes enzymes that have the tendency to expand and erode the bony structure underlying it and cause intracranial and extracranial complications. This cystic mass is in an abnormal location such as the middle ear, the petrous apex, or the external auditory canal (EAC). It is mostly found in the middle ear and rarely in the EAC. Here we have reported a rare case of unilateral primary EAC cholesteatoma with mild hearing loss in a middle-aged male. Case Report  We have reported a case of a 34-year-old male with complaints of right-sided ear discharge and right-sided decreased hearing for the last 5 to 6 years. On examination, right ear EAC was found to be dry, and a sac was observed in posterior wall extending to mastoid present with clear attic, and intact retracted tympanic membrane that was then followed by radiological evaluation to establish the diagnosis of EAC cholesteatoma. This was surgically treated and ear was cleared of all disease. Patient's symptoms improved postoperatively. Conclusion  Primary EAC cholesteatoma with disease-free middle ear is a rare finding and there is very less definitive literature available on the pathogenesis of the same.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82976986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atraumatic Isolated Bilateral Fibular Shaft Fragility Fracture: A Rare Case 非外伤性孤立性双侧腓骨干脆性骨折一例
Pub Date : 2023-04-04 DOI: 10.1055/s-0043-1764363
Suryakanth Kalluraya, AA Hosangadi, Prabhu P. Munavalli, Akash Kumar
Abstract Fragility fractures, a form of stress fracture brought on by physiological stress on weak bones, are not common. It might be challenging to diagnose a fragility fracture since a standard radiograph shows signs of fracture repair rather than the actual fracture. We present a case of a 32-year-old woman who has been complaining of both leg pain for the last 4 months and has been unable to stand for the last 1 week. Further analysis revealed that her vitamin D levels were insufficient.
摘要脆性骨折是一种由生理应力对弱骨造成的应力性骨折,并不常见。诊断脆性骨折可能具有挑战性,因为标准的x线片显示的是骨折修复的迹象,而不是实际的骨折。我们报告一个32岁的女性病例,她在过去的4个月里一直抱怨双腿疼痛,并且在过去的1周内无法站立。进一步的分析显示,她的维生素D水平不足。
{"title":"Atraumatic Isolated Bilateral Fibular Shaft Fragility Fracture: A Rare Case","authors":"Suryakanth Kalluraya, AA Hosangadi, Prabhu P. Munavalli, Akash Kumar","doi":"10.1055/s-0043-1764363","DOIUrl":"https://doi.org/10.1055/s-0043-1764363","url":null,"abstract":"Abstract Fragility fractures, a form of stress fracture brought on by physiological stress on weak bones, are not common. It might be challenging to diagnose a fragility fracture since a standard radiograph shows signs of fracture repair rather than the actual fracture. We present a case of a 32-year-old woman who has been complaining of both leg pain for the last 4 months and has been unable to stand for the last 1 week. Further analysis revealed that her vitamin D levels were insufficient.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"137 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76773623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology and Treatment Outcome of Blast Injuries to the Hand at a Tertiary Hospital of Kashmir Valley, India 印度克什米尔山谷一家三级医院手部爆炸伤的流行病学和治疗结果
Pub Date : 2023-04-04 DOI: 10.1055/s-0043-1762569
Junaid Khurshid, S. A. Bashir, A. Rasool, Onkar Kulkarni
Abstract Background:  Blast injuries to hand can have disastrous consequences on account of loss of critical hand functions. This study was conducted to study the epidemiology and outcome of hand blast injuries reporting to emergency department of a tertiary care hospital. Materials and Methods:  All the blast injuries to hand admitted at our center between 2016 and 2020 were assessed at the time of injury and at 6 weeks after completion of primary management. The severity of injury and functional outcome was assessed using modified hand injury severity score (HISS) and quick disabilities of the arm, shoulder and hand (QuickDASH) scale, respectively. Descriptive statistics was calculated and correlation between HISS and DASH was assessed using Pearson's correlation coefficient. Results:  A total of 26 cases with a mean age of 23.12 ± 9.1 years were included. The subjects included 25 males and 22 subjects had injury to their dominant hand. The grade of injury was severe in 12 (46.15%) cases followed by moderate in 5 (19.2%) cases and major in 5 (19.2%) cases. The mean HISS score at injury was 67.46 ± 37.6. The mean QuickDASH score at follow-up was 37.24 ± 29.7. QuickDASH score at follow-up had a significant correlation with HISS score at baseline with a Pearson's correlation coefficient of ( r  = 0.67, p  = 0.0012) Conclusions:  Blast injuries to hands are primarily seen in young males with low-grade explosives being the primary source of injury. Dominant hand is most commonly involved with many cases needing revascularization procedures. Higher severity of blast injuries to hand is associated with poor outcome at follow-up.
背景:由于手部关键功能的丧失,手部爆炸伤害会造成灾难性的后果。本研究旨在探讨某三级医院急诊科手部爆炸伤的流行病学及转归。材料与方法:2016年至2020年期间在我中心收治的所有手部爆炸伤患者在受伤时及初步处理完成后6周进行评估。分别采用改进的手部损伤严重程度评分(HISS)和手臂、肩部和手部快速残疾(QuickDASH)量表评估损伤严重程度和功能结局。进行描述性统计,并采用Pearson相关系数评价HISS与DASH的相关性。结果:共纳入26例,平均年龄23.12±9.1岁。研究对象包括25名男性,其中22名有惯用手损伤。损伤程度为重度12例(46.15%),其次为中度5例(19.2%),重度5例(19.2%)。损伤时HISS平均评分67.46±37.6。随访时QuickDASH平均得分为37.24±29.7。随访时的QuickDASH评分与基线时的HISS评分具有显著的相关性,Pearson相关系数为(r = 0.67, p = 0.0012)。结论:手爆炸伤主要见于年轻男性,低品位爆炸物是主要的伤害来源。在许多需要进行血运重建手术的病例中,优势手是最常见的。手部爆炸伤的严重程度越高,随访结果越差。
{"title":"Epidemiology and Treatment Outcome of Blast Injuries to the Hand at a Tertiary Hospital of Kashmir Valley, India","authors":"Junaid Khurshid, S. A. Bashir, A. Rasool, Onkar Kulkarni","doi":"10.1055/s-0043-1762569","DOIUrl":"https://doi.org/10.1055/s-0043-1762569","url":null,"abstract":"Abstract Background:  Blast injuries to hand can have disastrous consequences on account of loss of critical hand functions. This study was conducted to study the epidemiology and outcome of hand blast injuries reporting to emergency department of a tertiary care hospital. Materials and Methods:  All the blast injuries to hand admitted at our center between 2016 and 2020 were assessed at the time of injury and at 6 weeks after completion of primary management. The severity of injury and functional outcome was assessed using modified hand injury severity score (HISS) and quick disabilities of the arm, shoulder and hand (QuickDASH) scale, respectively. Descriptive statistics was calculated and correlation between HISS and DASH was assessed using Pearson's correlation coefficient. Results:  A total of 26 cases with a mean age of 23.12 ± 9.1 years were included. The subjects included 25 males and 22 subjects had injury to their dominant hand. The grade of injury was severe in 12 (46.15%) cases followed by moderate in 5 (19.2%) cases and major in 5 (19.2%) cases. The mean HISS score at injury was 67.46 ± 37.6. The mean QuickDASH score at follow-up was 37.24 ± 29.7. QuickDASH score at follow-up had a significant correlation with HISS score at baseline with a Pearson's correlation coefficient of ( r  = 0.67, p  = 0.0012) Conclusions:  Blast injuries to hands are primarily seen in young males with low-grade explosives being the primary source of injury. Dominant hand is most commonly involved with many cases needing revascularization procedures. Higher severity of blast injuries to hand is associated with poor outcome at follow-up.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90853823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antimicrobial Prescription Pattern in ENT Outpatient Department in a Tertiary Care Teaching Hospital, Telangana, India 印度特伦加纳三级护理教学医院耳鼻喉科门诊部抗菌药物处方模式
Pub Date : 2023-04-04 DOI: 10.1055/s-0043-1761502
Naveen Aalasyam, Shilpa Potnuru, Chandra Mouli Sileveru, Uma Pokala, N. P.
Abstract Introduction  Otorhinolaryngological infections are very common in adults and in children also. These infections are caused by various microorganisms and to treat these infections, antimicrobial agents are used frequently. As irrational use of antimicrobials leads to the development of antibiotic resistance and it is a big threat to the society, the present study was planned to get awareness among the practitioners regarding the antimicrobial prescription pattern. Aim  To study the prescription pattern of antimicrobial agents in outpatient department of otorhinolaryngology in a tertiary care teaching hospital. Materials and Methods  An observational study was planned over a period of 8 months from July 2019 to February 2020 in ENT outpatient department (OPD) at Mamata General Hospital, Khammam in Telangana. In total, 562 prescriptions were collected. Patient's details, probable diagnosis, prescribed medication details such as generic name, dose, and dosage forms were taken. The collected data was analyzed and the conclusions were drawn using descriptive analysis. Results  Total number of prescriptions were 562. The majority of the prescriptions belonged to the 21 to 40 years of age group. Males were included more than females (males 320 and females 242). Chronic suppurative otitis media (CSOM) (16.2%) was the commonest infection. Most commonly prescribed antimicrobial was amoxicillin and clavulanic acid combination (26.17%), followed by cefpodoxime with clavulanic acid (21.9%) and ciprofloxacin (19.06%). In 371 (66.01%) prescriptions, only one antimicrobial was prescribed, whereas in 36 (6.40%) prescriptions no antibiotic was given. The average number of drugs per prescription was 3.18 and the average number of antimicrobials per prescription was 1.25. Tablet form (52.9%) was the commonest dosage form and most of the drugs were prescribed by generic name (74.06%). Conclusion  The present study though prescription pattern of antibiotics and adherence to the hospital formulary by the physicians in the hospital is encouraging, still there is a chance in reducing the number of drugs prescribed per patient. The findings of this study will be useful to prescribe antimicrobials rationally so that the patient and health care system on the whole will be benefited.
摘要耳鼻喉科感染在成人和儿童中都很常见。这些感染是由各种微生物引起的,为了治疗这些感染,经常使用抗菌药物。由于抗菌药物的不合理使用导致抗生素耐药性的发展,对社会构成了很大的威胁,因此本研究旨在提高从业人员对抗菌药物处方模式的认识。目的了解某三级教学医院耳鼻喉科门诊抗菌药物的使用情况。材料和方法计划于2019年7月至2020年2月在泰伦加纳邦Khammam的Mamata总医院耳鼻喉科门诊部(OPD)进行为期8个月的观察性研究。共收集处方562张。患者的详细信息,可能的诊断,处方药物的详细信息,如通用名称,剂量和剂型。对收集到的数据进行分析,并采用描述性分析得出结论。结果处方总数为562张。大多数处方属于21至40岁年龄组。男性多于女性(男性320例,女性242例)。慢性化脓性中耳炎(CSOM)是最常见的感染(16.2%)。最常用的抗菌药物是阿莫西林与克拉维酸联合用药(26.17%),其次是头孢多肟与克拉维酸联合用药(21.9%)和环丙沙星(19.06%)。371张(66.01%)处方中仅开了一种抗菌药物,36张(6.40%)处方中未开抗生素。平均每张处方的药品数量为3.18种,平均每张处方的抗菌药物数量为1.25种。片剂是最常见的剂型(52.9%),以通用名开具的占比最高(74.06%)。结论我院抗菌药物的处方模式和医师对医院处方的依从性令人鼓舞,但在减少患者人均用药数量方面仍有机会。本研究结果将有助于合理处方抗菌药物,从而使患者和整个卫生保健系统受益。
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引用次数: 0
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International Journal of Recent Surgical and Medical Sciences
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