Background Intra-abdominal hypertension (IAH) is increasingly reported in patients with acute pancreatitis, and is caused by visceral edema, massive fluid resuscitation, paralytic ileus, and retroperitoneal inflammation. Patients with acute severe pancreatitis actually suffer from abdominal compartment syndrome (ACS)/IAH and since there is a strong correlation between early organ dysfunction and mortality in these patients, IAH appears to be an active and attractive target for early analysis and intervention.1 Aim The study is undertaken to estimate the significance of intra-abdominal pressure monitoring in acute severe pancreatitis. Objectives The objective of this study is to evaluate relationship between intra-abdominal pressure (IAP) and severity of acute pancreatitis and measure outcome in the form of intensive care unit (ICU) stay, hospital stay, treatment modality, and condition on discharge. Methodology A total of 50 patients diagnosed as acute severe pancreatitis were enrolled in this observational study. IAP monitoring was started on admission, once after controlling pain and then every 4 hours. IAP was measured via transvesical route. Data were collected on the length of the hospital stay, the development of systemic inflammatory response syndrome (SIRS), multiorgan failure, the extent of necrosis, the presence of infection, and mortality. Results IAH was present in 86% of patients with acute severe pancreatitis, which shows IAP monitoring is essential in managing these patients. Severity estimation by IAP monitoring is consistent with alternative laboratory parameters like Ranson's score (p = 0.002), SIRS (p = 0.013), organ failure/multiple organ dysfunction syndrome (p = 0.009). Two deaths were incurred during the study period. Conclusions IAP measurement in acute severe pancreatitis is a cost-effective and prognostic marker. Timely diagnosis and management of IAH/ACS through IAP monitoring can prevent major comorbidity (ICU/hospital stay) and mortality.
{"title":"Intra-Abdominal Pressure Monitoring in Acute Severe Pancreatitis—A Boon or Bane?","authors":"N. Ahamed, Kanagaraj Patchiannan","doi":"10.1055/s-0042-1743452","DOIUrl":"https://doi.org/10.1055/s-0042-1743452","url":null,"abstract":"\u0000 Background Intra-abdominal hypertension (IAH) is increasingly reported in patients with acute pancreatitis, and is caused by visceral edema, massive fluid resuscitation, paralytic ileus, and retroperitoneal inflammation. Patients with acute severe pancreatitis actually suffer from abdominal compartment syndrome (ACS)/IAH and since there is a strong correlation between early organ dysfunction and mortality in these patients, IAH appears to be an active and attractive target for early analysis and intervention.1\u0000 \u0000 Aim The study is undertaken to estimate the significance of intra-abdominal pressure monitoring in acute severe pancreatitis.\u0000 Objectives The objective of this study is to evaluate relationship between intra-abdominal pressure (IAP) and severity of acute pancreatitis and measure outcome in the form of intensive care unit (ICU) stay, hospital stay, treatment modality, and condition on discharge.\u0000 Methodology A total of 50 patients diagnosed as acute severe pancreatitis were enrolled in this observational study. IAP monitoring was started on admission, once after controlling pain and then every 4 hours. IAP was measured via transvesical route. Data were collected on the length of the hospital stay, the development of systemic inflammatory response syndrome (SIRS), multiorgan failure, the extent of necrosis, the presence of infection, and mortality.\u0000 Results IAH was present in 86% of patients with acute severe pancreatitis, which shows IAP monitoring is essential in managing these patients. Severity estimation by IAP monitoring is consistent with alternative laboratory parameters like Ranson's score (p = 0.002), SIRS (p = 0.013), organ failure/multiple organ dysfunction syndrome (p = 0.009). Two deaths were incurred during the study period.\u0000 Conclusions IAP measurement in acute severe pancreatitis is a cost-effective and prognostic marker. Timely diagnosis and management of IAH/ACS through IAP monitoring can prevent major comorbidity (ICU/hospital stay) and mortality.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78266428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Sajjan, Rahul Bhat, Manohar v. Pai, R. Choudhari
Abstract Introduction Heparin is useful in inflammatory conditions for amelioration of symptoms by altering the microcellular environment. This study was aimed at evaluation of the role of heparin in patients with cellulitis on antibiotics. Methodology In our prospective nonrandomized comparative study, the subjects were divided into two groups: group A treated with subcutaneous injection of unfractionated heparin plus antibiotics and group B with antibiotics alone. Comparison was done in terms of improvement in clinical parameters like erythema (cellulitis area), edema (measuring limb girth), pain (visual analog scale), total leucocyte count, and duration of hospital stay. Results Total of 96 patients were divided into two groups of 48 each. In the experimental group, there was improvement in mean area of cellulitis with decrease of 32.36% compared with 10.99% in controls treated with antibiotics at day 5 ( p < 0.001). There was 26.27% decrease in edema compared with 12.87% ( p < 0.001). There was 45.36% decrease of pain compared with 38.02% ( p < 0.001). There was 29.18% drop in total leucocyte counts compared with 25.87% ( p < 0.001). There was reduced duration of stay at 7.15 days compared with 9.23 days in controls. Conclusion The addition of heparin with antibiotic therapy in cellulitis hastens recovery with faster amelioration of symptoms and shorter hospital stay.
{"title":"Evaluation of Efficacy of Heparin in Patients with Cellulitis","authors":"S. Sajjan, Rahul Bhat, Manohar v. Pai, R. Choudhari","doi":"10.1055/s-0042-1751311","DOIUrl":"https://doi.org/10.1055/s-0042-1751311","url":null,"abstract":"Abstract Introduction Heparin is useful in inflammatory conditions for amelioration of symptoms by altering the microcellular environment. This study was aimed at evaluation of the role of heparin in patients with cellulitis on antibiotics. Methodology In our prospective nonrandomized comparative study, the subjects were divided into two groups: group A treated with subcutaneous injection of unfractionated heparin plus antibiotics and group B with antibiotics alone. Comparison was done in terms of improvement in clinical parameters like erythema (cellulitis area), edema (measuring limb girth), pain (visual analog scale), total leucocyte count, and duration of hospital stay. Results Total of 96 patients were divided into two groups of 48 each. In the experimental group, there was improvement in mean area of cellulitis with decrease of 32.36% compared with 10.99% in controls treated with antibiotics at day 5 ( p < 0.001). There was 26.27% decrease in edema compared with 12.87% ( p < 0.001). There was 45.36% decrease of pain compared with 38.02% ( p < 0.001). There was 29.18% drop in total leucocyte counts compared with 25.87% ( p < 0.001). There was reduced duration of stay at 7.15 days compared with 9.23 days in controls. Conclusion The addition of heparin with antibiotic therapy in cellulitis hastens recovery with faster amelioration of symptoms and shorter hospital stay.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"125 1","pages":"034 - 038"},"PeriodicalIF":0.0,"publicationDate":"2022-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81765534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rajashree S. Purohit, Gauri Jadhav, Geeta D. Adhikari, Ravindra S. Patwadkar, Yogesh R. Gaikwad
Calcinosis cutis is an uncommon disorder identified by the deposition of calcium in the skin and subcutaneous tissue. Idiopathic variety of calcinosis cutis is the one with no underlying damage at the tissue level or an absence of systemic derangement in the calcium and phosphorus metabolism. Here, we report a case of a 65-year-old female diagnosed with idiopathic calcinosis cutis of the hip after her calcium and phosphorus levels were found to be normal and no connective tissue disorder could be identified.
{"title":"Idiopathic Calcinosis Cutis of Hip: A Case Report and Review of Literature","authors":"Rajashree S. Purohit, Gauri Jadhav, Geeta D. Adhikari, Ravindra S. Patwadkar, Yogesh R. Gaikwad","doi":"10.1055/s-0042-1751233","DOIUrl":"https://doi.org/10.1055/s-0042-1751233","url":null,"abstract":"Calcinosis cutis is an uncommon disorder identified by the deposition of calcium in the skin and subcutaneous tissue. Idiopathic variety of calcinosis cutis is the one with no underlying damage at the tissue level or an absence of systemic derangement in the calcium and phosphorus metabolism. Here, we report a case of a 65-year-old female diagnosed with idiopathic calcinosis cutis of the hip after her calcium and phosphorus levels were found to be normal and no connective tissue disorder could be identified.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76054593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Introduction Proximal humerus fractures in the osteoporotic elderly population are increasing and difficult to treat. Treatment in proximal fracture fixation in elderly has changed from absolute stability to relative stability that preserves soft tissue and vascularity, thereby improving clinical outcomes. Aims and Objectives This study aimed to evaluate the clinical outcome of proximal humerus fractures in osteoporotic patients using minimally invasive J-nailing technique. Methods and Materials A prospective observational study was done on 25 patients with proximal humerus fractures belonging to Neer's classification type 2 and 3 operated between May 2018 and June 2020 in the department of orthopaedics in tertiary health care center and treated by multiple intramedullary blunt Kirschner wires (J-nailing technique). The patients were followed up at 2, 6, 12, and 36 weeks. At the end of follow-up, clinical outcome was assessed using Neer's scoring system. Results Treatment of proximal humerus fractures with J-nailing technique in the elderly population has shown promising results both in terms of function and radiology. Mean union time was 13.48 weeks with a standard deviation of 1.19 weeks. We did not find any significant difference in union time between patients with fracture type 2-part and 3-part. However, there was a significant difference in Neer's scoring between patients with fracture types two-part and three-part. Conclusion Proximal humerus fracture fixation using minimally invasive techniques with J-nailing is an effective method of stabilization in elderly osteoporotic population, yielding good mechanical alignment, protecting rotator cuff muscles, preserving blood supply and predictable union rates with good clinical results.
{"title":"Minimally Invasive Osteosynthesis in Elderly Osteoporotic Proximal Humerus Fractures Using J-Nailing Technique","authors":"P. Tathe, Nilesh S. Sakharkar, A. Ingale","doi":"10.1055/s-0042-1744182","DOIUrl":"https://doi.org/10.1055/s-0042-1744182","url":null,"abstract":"Abstract Introduction Proximal humerus fractures in the osteoporotic elderly population are increasing and difficult to treat. Treatment in proximal fracture fixation in elderly has changed from absolute stability to relative stability that preserves soft tissue and vascularity, thereby improving clinical outcomes. Aims and Objectives This study aimed to evaluate the clinical outcome of proximal humerus fractures in osteoporotic patients using minimally invasive J-nailing technique. Methods and Materials A prospective observational study was done on 25 patients with proximal humerus fractures belonging to Neer's classification type 2 and 3 operated between May 2018 and June 2020 in the department of orthopaedics in tertiary health care center and treated by multiple intramedullary blunt Kirschner wires (J-nailing technique). The patients were followed up at 2, 6, 12, and 36 weeks. At the end of follow-up, clinical outcome was assessed using Neer's scoring system. Results Treatment of proximal humerus fractures with J-nailing technique in the elderly population has shown promising results both in terms of function and radiology. Mean union time was 13.48 weeks with a standard deviation of 1.19 weeks. We did not find any significant difference in union time between patients with fracture type 2-part and 3-part. However, there was a significant difference in Neer's scoring between patients with fracture types two-part and three-part. Conclusion Proximal humerus fracture fixation using minimally invasive techniques with J-nailing is an effective method of stabilization in elderly osteoporotic population, yielding good mechanical alignment, protecting rotator cuff muscles, preserving blood supply and predictable union rates with good clinical results.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"27 1","pages":"045 - 052"},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83360903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Kausar, A. Tripathi, R. Kaushik, S. Khare, Shilpi Jain, Shobhit Raizaday
Abstract Introduction This histopathological study was done with an aim to learn about the biohazardous effects of chromium toxicity with protective role of alpha-tocopherol on liver parenchyma of albino rat when fed orally. Materials and Methods The study was conducted in the Department of Anatomy at Subharti Medical College, Meerut (Uttar Pradesh), India, in collaboration with Department of Pathology and Pharmacology. The experiment was conducted as per the guidelines of the Committee for Purpose of Control and Supervision of Experiments on Animals, with registration number 1204/PO/Re/S/2008/CPSEA, and with permission of the Animal Ethical Committee, on 36 adult male rats of ∼60 days of age; 140 ± 20 g of body weight was used; all the experimental animals were kept in polypropylene cage, and fed with pellet diet and water. Result When exposed to chromium for long, it resulted in toxicity and damaged the cellular components during reduction process of chromium by releasing of free radicals, leading to deoxyribonucleic acid damage, but the chain-breaking antioxidant effects of alpha-tocopherol played an important role by reversing the damage caused by chromium toxicity, hence proved hepatoprotective. Conclusion Vitamin E (alpha-tocopherol) is proved to be hepatoprotective against hepatotoxic effect of chromium metal.
{"title":"Histopathological Changes on Liver Architecture Due to Toxic Effect of Chromium with Protective Role of Vitamin E on Albino Rats: A Prospective Study","authors":"H. Kausar, A. Tripathi, R. Kaushik, S. Khare, Shilpi Jain, Shobhit Raizaday","doi":"10.1055/s-0042-1743449","DOIUrl":"https://doi.org/10.1055/s-0042-1743449","url":null,"abstract":"Abstract Introduction This histopathological study was done with an aim to learn about the biohazardous effects of chromium toxicity with protective role of alpha-tocopherol on liver parenchyma of albino rat when fed orally. Materials and Methods The study was conducted in the Department of Anatomy at Subharti Medical College, Meerut (Uttar Pradesh), India, in collaboration with Department of Pathology and Pharmacology. The experiment was conducted as per the guidelines of the Committee for Purpose of Control and Supervision of Experiments on Animals, with registration number 1204/PO/Re/S/2008/CPSEA, and with permission of the Animal Ethical Committee, on 36 adult male rats of ∼60 days of age; 140 ± 20 g of body weight was used; all the experimental animals were kept in polypropylene cage, and fed with pellet diet and water. Result When exposed to chromium for long, it resulted in toxicity and damaged the cellular components during reduction process of chromium by releasing of free radicals, leading to deoxyribonucleic acid damage, but the chain-breaking antioxidant effects of alpha-tocopherol played an important role by reversing the damage caused by chromium toxicity, hence proved hepatoprotective. Conclusion Vitamin E (alpha-tocopherol) is proved to be hepatoprotective against hepatotoxic effect of chromium metal.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"26 1","pages":"028 - 033"},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86011822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Introduction Etiology of vertigo is wide and each etiological factor should be treated accordingly. This study was conducted to assess the prevalence of cervical spondylosis among the cases with vertigo and to assess the clinical factors associated with it. Materials and Methods A hospital-based cross-sectional study was conducted among cases with vertigo attending the outpatient department of otorhinolaryngology at Chettinad Hospital and Research Institute, Chennai, Tamil Nadu, India, during the months of November 2020 to March 2021. A total of 180 cases with vertigo and 180 controls without vertigo were included in the study. Primary outcome assessed was the prevalence of cervical spondylosis among cases with vertigo and the secondary outcome was to assess the clinical characteristics of the study participants and factors associated with the presence of cervical spondylosis. Analysis was done using SPSS version 20. Results Majority of participants belong to 51 to 55 years of age with slight female predominance. Impacted cerumen auris, otitis media, and perforated tympanic membrane were noted in 19.4, 10, and 10.6% of cases, respectively. Prevalence of cervical spondylosis was reported as 17.2%, and 12.2% of cases had abnormal pure-tone audiometry findings with significant association between the presences of cervical spondylosis. Conclusion Assessment of hearing using pure-tone audiometry can be done as a routine practice for all the cases with vertigo which occurs due to cervical spondylosis.
眩晕的病因很广，对各种病因都要进行相应的治疗。本研究旨在评估眩晕患者中颈椎病的患病率，并评估与之相关的临床因素。材料与方法对2020年11月至2021年3月在印度泰米尔纳德邦金奈Chettinad医院和研究所耳鼻喉科门诊就诊的眩晕病例进行了一项基于医院的横断面研究。本研究共纳入180例眩晕患者和180例非眩晕对照组。评估的主要结果是眩晕患者中颈椎病的患病率，次要结果是评估研究参与者的临床特征和与颈椎病存在相关的因素。使用SPSS version 20进行分析。结果参与者年龄以51 ~ 55岁居多，女性略占优势。耳垢阻生、中耳炎和鼓膜穿孔分别占19.4%、10%和10.6%。据报道，颈椎病的患病率为17.2%，12.2%的病例有异常的纯音听力学结果，颈椎病的存在之间有显著的关联。结论纯音听力法可作为颈椎病所致眩晕的常规听力评估方法。
{"title":"Prevalence of Cervical Spondylosis among Cases with Vertigo in a Tertiary Care Center","authors":"P. S., Raghvi A., R. V., N. Rb, R. S","doi":"10.1055/s-0042-1751314","DOIUrl":"https://doi.org/10.1055/s-0042-1751314","url":null,"abstract":"Abstract Introduction Etiology of vertigo is wide and each etiological factor should be treated accordingly. This study was conducted to assess the prevalence of cervical spondylosis among the cases with vertigo and to assess the clinical factors associated with it. Materials and Methods A hospital-based cross-sectional study was conducted among cases with vertigo attending the outpatient department of otorhinolaryngology at Chettinad Hospital and Research Institute, Chennai, Tamil Nadu, India, during the months of November 2020 to March 2021. A total of 180 cases with vertigo and 180 controls without vertigo were included in the study. Primary outcome assessed was the prevalence of cervical spondylosis among cases with vertigo and the secondary outcome was to assess the clinical characteristics of the study participants and factors associated with the presence of cervical spondylosis. Analysis was done using SPSS version 20. Results Majority of participants belong to 51 to 55 years of age with slight female predominance. Impacted cerumen auris, otitis media, and perforated tympanic membrane were noted in 19.4, 10, and 10.6% of cases, respectively. Prevalence of cervical spondylosis was reported as 17.2%, and 12.2% of cases had abnormal pure-tone audiometry findings with significant association between the presences of cervical spondylosis. Conclusion Assessment of hearing using pure-tone audiometry can be done as a routine practice for all the cases with vertigo which occurs due to cervical spondylosis.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"3 1","pages":"023 - 027"},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75234251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Background Social media has been defined as a form of electronic communication that is used for communication and expression of thoughts. It is a boon for the young generation as it has a lot of positive impacts like global connectivity, easy/inexpensive communication, and sharing of information; however, it is associated with serious adverse effects/imprints on the mental health of adolescent's developing brain. Method This was an observational, cross-sectional study on 200 students from two government schools. After obtaining consent from parents and teacher, students were asked to fill a preprinted form containing a 12-point survey questionnaire, Beck Depression Inventory for assessment of depression, and a 12-Item General Health Questionnaire (12-item GHQ) for the assessment of common mental health disorders. Obtained data was analyzed among social media users and nonusers. Results The study included 200 adolescents, 84 (42%) were of 11th standard and 116 (58%) were of 12th standard. Eighty-five adolescents (42.5%) were males and 115 (57.5%) were females; median age was 14 years. The mean Beck Depression Inventory score among users was 11.47 +7.54 as compared with 6.702 +6.67 among nonusers, p = 0.0005, significant. The mean 12-item GHQ score among users was 7.631 + 5.37 as compared with 7.05 + 5.79 among nonusers, p = 0.5589, insignificant. About 82.8% students used WhatsApp, 39.8% used Facebook, 40.4% used Instagram, 26.9% used Snapchat, and 17.17% used YouTube. Conclusion Majority of adolescents are using social media nowadays and are found to have various mental health problems in this study. This highlights the importance of awareness among parents, teachers, and adolescent health-care providers.
{"title":"Impact of Use of Social Media on Adolescent's Mental Health in a Tier 2 City—A Cross-Sectional Study","authors":"Arpit Sohane, P. Ghanghoriya, A. Tiwari","doi":"10.1055/s-0042-1743450","DOIUrl":"https://doi.org/10.1055/s-0042-1743450","url":null,"abstract":"Abstract Background Social media has been defined as a form of electronic communication that is used for communication and expression of thoughts. It is a boon for the young generation as it has a lot of positive impacts like global connectivity, easy/inexpensive communication, and sharing of information; however, it is associated with serious adverse effects/imprints on the mental health of adolescent's developing brain. Method This was an observational, cross-sectional study on 200 students from two government schools. After obtaining consent from parents and teacher, students were asked to fill a preprinted form containing a 12-point survey questionnaire, Beck Depression Inventory for assessment of depression, and a 12-Item General Health Questionnaire (12-item GHQ) for the assessment of common mental health disorders. Obtained data was analyzed among social media users and nonusers. Results The study included 200 adolescents, 84 (42%) were of 11th standard and 116 (58%) were of 12th standard. Eighty-five adolescents (42.5%) were males and 115 (57.5%) were females; median age was 14 years. The mean Beck Depression Inventory score among users was 11.47 +7.54 as compared with 6.702 +6.67 among nonusers, p = 0.0005, significant. The mean 12-item GHQ score among users was 7.631 + 5.37 as compared with 7.05 + 5.79 among nonusers, p = 0.5589, insignificant. About 82.8% students used WhatsApp, 39.8% used Facebook, 40.4% used Instagram, 26.9% used Snapchat, and 17.17% used YouTube. Conclusion Majority of adolescents are using social media nowadays and are found to have various mental health problems in this study. This highlights the importance of awareness among parents, teachers, and adolescent health-care providers.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"80 1","pages":"018 - 022"},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79147562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Navya, V. Srisanthanakrishnan, P. M. Safneedha, V. Ranganathan
Abstract Aim The aim of this study was to compare the extent of analgesia in terms of duration of analgesia and requirement of postoperative analgesics with preemptive analgesia and transversus abdominis plane (TAP) block in patients undergoing inguinal hernioplasty. Materials and Methods Ninety male patients aged between 18 and 65 years of American Society of Anesthesiologists grades I and II undergoing open inguinal hernioplasty were randomly allocated to three comparable groups of 30 each. Control group (group C) received normal saline; preemptive group (group P) received inj. paracetamol, inj. diclofenac, and inj. Lignocaine; and TAP group (group T) received TAP block with 20 mL of 0.25% bupivacaine at the end of surgery. Parameters recorded were verbal numerical rating scale (VNRS) at rest at 4, 12, 24, and 48 hours and VNRS on movement at 12, 24, and 48 hours; heart rate and mean arterial pressure at 0, 4, 12, and 48 hours; time for first analgesic request; and total doses of analgesics consumed at 24 hours. Results Demographic data were comparable. VNRS on movement and number of doses of analgesics consumed at 24 hours were statistically less in group T (4.80 ± .761 hours); time for first request of analgesia was longer and this group had better patient satisfaction scores compared with other groups. Conclusion Both groups P and T provided better VNRS scores compared with group C. TAP block provided better VNRS scores on movement at 24 hours, lesser analgesic requirement, and better patient satisfaction score compared with other groups.
{"title":"Evaluation of Effectiveness of Preemptive Intravenous Analgesics versus Postoperative TAP Block in Unilateral Inguinal Hernioplasty—A Prospective Randomized Double-Blind Clinical Trial","authors":"C. Navya, V. Srisanthanakrishnan, P. M. Safneedha, V. Ranganathan","doi":"10.1055/s-0042-1747922","DOIUrl":"https://doi.org/10.1055/s-0042-1747922","url":null,"abstract":"Abstract Aim The aim of this study was to compare the extent of analgesia in terms of duration of analgesia and requirement of postoperative analgesics with preemptive analgesia and transversus abdominis plane (TAP) block in patients undergoing inguinal hernioplasty. Materials and Methods Ninety male patients aged between 18 and 65 years of American Society of Anesthesiologists grades I and II undergoing open inguinal hernioplasty were randomly allocated to three comparable groups of 30 each. Control group (group C) received normal saline; preemptive group (group P) received inj. paracetamol, inj. diclofenac, and inj. Lignocaine; and TAP group (group T) received TAP block with 20 mL of 0.25% bupivacaine at the end of surgery. Parameters recorded were verbal numerical rating scale (VNRS) at rest at 4, 12, 24, and 48 hours and VNRS on movement at 12, 24, and 48 hours; heart rate and mean arterial pressure at 0, 4, 12, and 48 hours; time for first analgesic request; and total doses of analgesics consumed at 24 hours. Results Demographic data were comparable. VNRS on movement and number of doses of analgesics consumed at 24 hours were statistically less in group T (4.80 ± .761 hours); time for first request of analgesia was longer and this group had better patient satisfaction scores compared with other groups. Conclusion Both groups P and T provided better VNRS scores compared with group C. TAP block provided better VNRS scores on movement at 24 hours, lesser analgesic requirement, and better patient satisfaction score compared with other groups.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"9 1","pages":"001 - 005"},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91122479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-01DOI: 10.32457/ijmss.v9i2.1848
N. Muñoz, J. Mosquera, A. Pedreáñez
The receptor for advanced glycation end products (RAGE) is implicated in the pathogenesis of several chronic diseases including diabetes. The interaction between RAGE and advanced glycation end products (AGEs) promotes gene expression, enhances the release of proinflammatory molecules and causes the generation of oxidative stress in numerous cell types. The aim of this investigation was to evaluate the effect of enalapril and losartan on RAGE expression in abdominal aortic endothelium of rats with experimentally induced diabetes. Male Sprague-Dawley rats, weighing approximately 150 - 200 g, were used. Diabetes was induced in 30 rats by intravenous administration of a single dose of 55 mg/kg body weight of streptozotocin (ETZ). The following groups were studied: control (n=10), diabetic (n=10), losartan-treated diabetic (n=10) and enalapril-treated diabetic (n=10) rats. RAGE expression in aortic endothelium was determined by indirect immunofluorescence. A significant increase in RAGE expression was observed in diabetic animals versus controls (p<0.001), there was a decrease in RAGE expression, in animals treated with losartan versus controls (p<0.01) and in those treated with enalapril (p<0.05) versus control and versus diabetes + vehicle. In conclusion, in the experimental model of ETZ-induced diabetes, there is an increase in RAGE expression at the level of the abdominal aortic endothelium, which can be reversed by treatment with losartan and/or enalapril, two drugs that block the renin-angiotensin system, suggesting its involvement in the molecular events related to vascular damage during diabetes.
{"title":"Endothelial expression of the receptor for advanced glycation end products in experimental diabetes","authors":"N. Muñoz, J. Mosquera, A. Pedreáñez","doi":"10.32457/ijmss.v9i2.1848","DOIUrl":"https://doi.org/10.32457/ijmss.v9i2.1848","url":null,"abstract":"The receptor for advanced glycation end products (RAGE) is implicated in the pathogenesis of several chronic diseases including diabetes. The interaction between RAGE and advanced glycation end products (AGEs) promotes gene expression, enhances the release of proinflammatory molecules and causes the generation of oxidative stress in numerous cell types. The aim of this investigation was to evaluate the effect of enalapril and losartan on RAGE expression in abdominal aortic endothelium of rats with experimentally induced diabetes. Male Sprague-Dawley rats, weighing approximately 150 - 200 g, were used. Diabetes was induced in 30 rats by intravenous administration of a single dose of 55 mg/kg body weight of streptozotocin (ETZ). The following groups were studied: control (n=10), diabetic (n=10), losartan-treated diabetic (n=10) and enalapril-treated diabetic (n=10) rats. RAGE expression in aortic endothelium was determined by indirect immunofluorescence. A significant increase in RAGE expression was observed in diabetic animals versus controls (p<0.001), there was a decrease in RAGE expression, in animals treated with losartan versus controls (p<0.01) and in those treated with enalapril (p<0.05) versus control and versus diabetes + vehicle. In conclusion, in the experimental model of ETZ-induced diabetes, there is an increase in RAGE expression at the level of the abdominal aortic endothelium, which can be reversed by treatment with losartan and/or enalapril, two drugs that block the renin-angiotensin system, suggesting its involvement in the molecular events related to vascular damage during diabetes.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82126053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdominal hernias are defects due to loss of continuity of the fasciae and/or muscles with the protrusion of abdominal structures. They are the third most prevalent and incident abdominal pathology worldwide and the second pathology of consultation in general surgery in patients of age limits. There are various factors that contribute to their formation, but within the scientific community there are various types of classifications, which differ according to the professional training school and their decision-making. This bibliographic review aims to expose the most used abdominal hernia classification systems such as the European one that has a morphological vision, the Ventral Hernia Working Group that proposes its aspect on recurrence together with the modified one that exposes comorbidity and the staging system of ventral hernia that provides a comprehensive approach to classification and management. In addition to the most common complications of the same.
{"title":"Abdominal Wall Hernias: different types of classifications and complications","authors":"Jesús Nicolás Larco Coloma, Nicolás Larco Noboa, Alegría Rumazo Zambrano","doi":"10.32457/ijmss.v9i2.1867","DOIUrl":"https://doi.org/10.32457/ijmss.v9i2.1867","url":null,"abstract":"Abdominal hernias are defects due to loss of continuity of the fasciae and/or muscles with the protrusion of abdominal structures. They are the third most prevalent and incident abdominal pathology worldwide and the second pathology of consultation in general surgery in patients of age limits. There are various factors that contribute to their formation, but within the scientific community there are various types of classifications, which differ according to the professional training school and their decision-making. This bibliographic review aims to expose the most used abdominal hernia classification systems such as the European one that has a morphological vision, the Ventral Hernia Working Group that proposes its aspect on recurrence together with the modified one that exposes comorbidity and the staging system of ventral hernia that provides a comprehensive approach to classification and management. In addition to the most common complications of the same.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77186240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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