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Estudio comparativo de la capacidad de aprendizaje de ChatGPT en la resolución de preguntas de especialización médica 比较研究 ChatGPT 在解决医学专业问题方面的学习能力。
Q4 Medicine Pub Date : 2024-06-04 DOI: 10.1016/j.opresp.2024.100340
Álvaro Fuentes-Martín , Ángel Cilleruelo-Ramos , Bárbara Segura-Méndez , Julio Mayol
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引用次数: 0
Long-Term Patient Symptoms and Quality of Life in Adults After COVID-19: A Real Life Study COVID-19 后成人患者的长期症状和生活质量。一项真实的研究
Q4 Medicine Pub Date : 2024-05-20 DOI: 10.1016/j.opresp.2024.100336
Oscar Perez , Miguel Santibañez , Laura Rasines , Jose Maria Castillo , Adrian Hugo Aginagalde-Llorente

Objective

To characterize long-term patient-reported symptoms and quality of life, in adults after COVID-19.

Material and methods

Cross-sectional study in Cantabria (Northern Spain) including adults with PCR-confirmed SARS-CoV-2 infection (n = 694) with a time period between 4.7 and 24 month post-SARS-CoV-2 diagnosis, and their close contacts (n = 663) (PCR negative and without suspected infection) obtained from simple random sampling of a total of 47,773 cases and 94,301 close contacts. The ISARIC survey was used as screening tool with self-reported “non-feeling fully recovery (NFFR)” defined as primary outcome.

Results

16.57% (n = 115/694) reported NFFR. Most prevalent symptoms were in order of frequency: Fatigue (54.8%); Loss of smell (40.9%); Problems speaking or communicating (29.6%); Loss of taste (28.7%); Confusion/lack of concentration (27.8%); Persistent muscle pain (24.3%) and Shortness of breath/breathlessness (23.5%). When comparing the three ordinal groups (Close contacts, COVID-19 feeling recovered, and COVID-19 NFFR) the prevalence of these symptoms was increasingly higher among each ordinal group (p < 0.001). Female gender was significantly associated with NFFR: (adjusted odds ratio (aOR) = 1.56); as well as older age: aOR per 10 year increment = 1.15. Lastly, they scored on average 9.63 points less in Euroquol.

Conclusions

More than 15% of patients in our real-life population-based study, reported NFFR, being female sex and older age independent predictors of this condition. Most symptoms in these patients were in accordance with WHO definition of post COVID-19 condition in adults, and were less prevalent in COVID-19 feeling recovered and close contact respectively, with a statistically significant dose-response pattern, and with a large decrease in quality of life according to Euroquol.

材料和方法在坎塔布里亚(西班牙北部)进行的横断面研究,包括 PCR 证实感染 SARS-CoV-2 的成年人(n = 694)(确诊后 4.7 个月至 24 个月之间),以及他们的密切接触者(n = 663)(PCR 阴性且无疑似感染)(从 47,773 例病例和 94,301 名密切接触者中简单随机抽样获得)。采用 ISARIC 调查作为筛查工具,以自我报告的 "未完全康复(NFFR)"作为主要结果。最常见的症状依次为疲劳(54.8%);嗅觉丧失(40.9%);说话或交流困难(29.6%);味觉丧失(28.7%);意识模糊/注意力不集中(27.8%);持续肌肉疼痛(24.3%)和呼吸急促/窒息(23.5%)。在比较三个序数组(密切接触者、COVID-19 感觉康复者和 COVID-19 非FFR)时,这些症状的发生率在每个序数组中都越来越高(p <0.001)。女性性别与 NFFR 有明显相关性:(调整后的几率比 (aOR) = 1.56);年龄越大,每 10 年的几率比 = 1.15。最后,他们在 Euroquol 中的得分平均降低了 9.63 分。结论在我们基于现实生活的人群研究中,有超过 15% 的患者报告了 NFFR,女性和高龄是这种情况的独立预测因素。这些患者的大多数症状都符合世界卫生组织对 COVID-19 后成人状况的定义,并且在 COVID-19 感觉恢复和密切接触中的发病率较低,在统计学上具有显著的剂量反应模式,根据 Euroquol 的评分,生活质量大幅下降。
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引用次数: 0
Combined Treatment Scenarios for Patients With Severe Asthma and Chronic Rhinosinusitis With Nasal Polyps. A Proposal From GEMA-POLINA Task Force 严重哮喘和慢性鼻炎合并鼻息肉患者的综合治疗方案。GEMA-POLINA工作组的建议
Q4 Medicine Pub Date : 2024-05-20 DOI: 10.1016/j.opresp.2024.100337
Vicente Plaza , Christian Calvo-Henríquez , Marina Blanco-Aparicio , Carlos Colás , Jorge del Estal , Noé Garín , Ruperto González-Pérez , Juan Maza-Solano , José Gregorio Soto , Isam Alobid
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引用次数: 0
High-Flow Oxygen: Respiratory Mechanics in Lung Alveoli of Patients After Acute Respiratory Failure 高流量氧气:急性呼吸衰竭患者肺泡中的呼吸力学
Q4 Medicine Pub Date : 2024-05-20 DOI: 10.1016/j.opresp.2024.100335
Alba Naya Prieto , Carlos López Chang , María del Pilar Carballosa de Miguel , Miren Itziar Fernández Ormaechea , María de los Ángeles Zambrano Chacón , Luis Jiménez Hiscock , Germán Peces-Barba Romero , María Jesús Rodríguez Nieto , Sarah Beatriz Heili Frades
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引用次数: 0
Influencia de las guías de práctica clínica en el diagnóstico y tratamiento de la fibrosis pulmonar idiopática. Datos del Registro de la Sociedad Española de Neumología y Cirugía Torácica 临床实践指南对特发性肺纤维化诊断和治疗的影响。来自西班牙肺病与胸外科学会(SEPAR)登记处的数据。
Q4 Medicine Pub Date : 2024-05-15 DOI: 10.1016/j.opresp.2024.100334
Myriam Aburto , José Antonio Rodríguez-Portal , Estrella Fernandez-Fabrellas , Raquel García Sevila , Susana Herrera Lara , Elena Bollo de Miguel , José María González Ruiz , María Molina-Molina , Belén Safont Muñoz , Raul Godoy Mayoral , Ana Dolores Romero Ortiz , María José Soler Sempere , Diego Castillo Villegas , Javier Gaudó Navarro , Laura Tomás López , Belén Nuñez Sanchez , Zulema Palacios Hidalgo , Jacobo Sellares Torres , Lirios Sacristán Bou , María Asunción Nieto Barbero , Claudia Valenzuela

Objective

The objective of the study was to analyze the diagnostic process and the time until the start of treatment of patients with idiopathic pulmonary fibrosis in relation to the publication of successive clinical practice guide.

Material and methods

Multicenter, observational, ambispective study, in which patients includes in the idiopathic pulmonary fibrosis registry of the Spanish Society of Pulmonologist and Thoracic Surgery were analyzed. An electronic data collection notebook was enabled on the society's website. Sociodemographic and clinical variables were collected at diagnosis and follow-up of the patients.

Results

From January 2012 to december 2019, 1064 patients were included in the registry, with 929 finally analyzed. The diagnosis process varied depending on the year in which it was performed, and the radiological pattern observed in the high-resolution computed tomography. Up to 26.3% of the cases (244) were diagnosed with chest high-resolution computed tomography and clinical evaluation. Surgical biopsy was used up to 50.2% of cases diagnosed before 2011, while it has been used in 14.2% since 2018. The median time from the onset of symptoms to diagnosis was 360 days (IQR 120-720), taking more than 2 years in the 21.0% of patients. A percentage of 79.4 of patients received antifibrotic treatment. The average time from diagnosis to the antifibrotic treatment has been 309 ± 596.5 days, with a median of 49 (IQR 0-307).

Conclusions

The diagnostic process, including the time until diagnosis and the type of test used, has changed from 2011 to 2019, probably due to advances in clinical research and the publication of diagnostic-therapeutic consensus guidelines.

该研究旨在分析特发性肺纤维化患者的诊断过程和开始治疗的时间与后续临床实践指南的发布之间的关系。材料和方法该研究是一项多中心、观察性、前瞻性研究,对西班牙肺科和胸外科学会特发性肺纤维化登记处的患者进行了分析。该学会的网站启用了电子数据收集笔记本。结果从2012年1月至2019年12月,共有1064名患者被纳入登记册,最终分析了929名患者。诊断过程因进行诊断的年份和高分辨率计算机断层扫描观察到的放射学模式而异。高达 26.3% 的病例(244 例)是通过胸部高分辨率计算机断层扫描和临床评估确诊的。在2011年之前确诊的病例中,50.2%采用了手术活检,而自2018年以来,14.2%采用了手术活检。从症状出现到确诊的中位时间为 360 天(IQR 120-720),21.0% 的患者超过 2 年。79.4%的患者接受了抗纤维化治疗。从诊断到接受抗纤维化治疗的平均时间为309±596.5天,中位数为49天(IQR 0-307)。结论可能是由于临床研究的进展和诊断治疗共识指南的发布,诊断过程,包括诊断前的时间和使用的检测类型,从2011年到2019年发生了变化。
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引用次数: 0
Impacto de la telemonitorización como sistema para una adecuada titulación y adaptación de la CPAP domiciliaria en la apnea obstructiva del sueño (proyecto T-CPAP) 远程监测系统对阻塞性睡眠呼吸暂停患者正确滴定和调整家用 CPAP 的影响(T-CPAP 项目)。
Q4 Medicine Pub Date : 2024-05-08 DOI: 10.1016/j.opresp.2024.100332
María Teresa Ramírez Prieto, M.a Vaneas Lores Gutiérrez, Raul Moreno Zabaleta, Rocío Rodríguez Pérez

Introduction

Continuous Positive Airway Pressure (CPAP) constitutes the most effective treatment for Obstructive Sleep Apnea (OSA). Automatic titration systems (ATS) are predominantly used to achieve adaptation to the equipment. Home CPAP devices allow telemonitoring (TM) of the same parameters as those provided by ATS but with access to continuous usage data. Under this premise, we conducted a study on the potential validity of TM for home CPAP devices as a titration system, its direct impact on proper adaptation (AD) to the equipment, and secondarily on the healthcare resources employed to achieve it.

Material and methods

An observational study involving 318 patients with OSA who were titrated using TM to achieve AD to CPAP. Patients with OSA were consecutively recruited and evaluated at 1, 3, and 6 months after initiating treatment. Results were compared with a historical group of 307 patients with OSA who achieved AD to CPAP using ATS. Additionally, we assessed the impact on required healthcare resources.

Results

Patients with OSA who initiated CPAP treatment with TM over the first six months showed a similar AD rate compared to the historical group titrated using ATS, with lower resource usage in the TM group.

Conclusion

Data provided by TM of home CPAP devices allow for titration and achieving similar AD as with ATS in non-complex patients.

导言持续气道正压(CPAP)是治疗阻塞性睡眠呼吸暂停(OSA)最有效的方法。自动滴定系统(ATS)主要用于实现对设备的适应。家用 CPAP 设备可以远程监控 (TM) 与自动滴定系统提供的参数相同的参数,但可以获取连续使用数据。在此前提下,我们对家用 CPAP 设备的 TM 作为滴定系统的潜在有效性、其对设备适当适应性(AD)的直接影响,以及其次对实现该目标所使用的医疗资源进行了研究。连续招募 OSA 患者,并在开始治疗后的 1、3 和 6 个月进行评估。我们将结果与 307 名使用 ATS 实现 AD 到 CPAP 的 OSA 患者进行了比较。此外,我们还评估了对所需医疗资源的影响。结果在最初 6 个月内开始使用 TM 进行 CPAP 治疗的 OSA 患者的 AD 率与使用 ATS 进行滴定的历史组相似,而 TM 组的资源使用率较低。
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引用次数: 0
Challenges in the Implementation of the Spanish Consensus on the Reduction of Oral Corticosteroids: Insights From the Medical Community 实施《西班牙减少口服皮质类固醇共识》的挑战:医学界的见解
Q4 Medicine Pub Date : 2024-05-08 DOI: 10.1016/j.opresp.2024.100331
Javier Dominguez-Ortega , Xavier Muñoz-Gall , Julio Delgado-Romero , Francisco Casas-Maldonado , Marina Blanco-Aparicio
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引用次数: 0
Avances y desafíos en el control de la tuberculosis multirresistente (TB-MDR) 控制耐多药结核病(MDR-TB)的进展与挑战
Q4 Medicine Pub Date : 2024-05-01 DOI: 10.1016/j.opresp.2024.100333
Eva Tabernero Huguet
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引用次数: 0
Supraglottic Stenosis After Caustic Ingestion 摄入腐蚀性物质后出现声门上狭窄
Q4 Medicine Pub Date : 2024-04-23 DOI: 10.1016/j.opresp.2024.100328
Sonia Salinas Castillo, Cristina López García-Gallo, Carlos Almonacid Sánchez
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引用次数: 0
Pulmonary Alveolar Proteinosis With Atypical Presentation Mimicking Acute Alveolar Sarcoidosis: A Challenging Diagnosis 模仿急性肺泡肉样瘤病的非典型肺泡蛋白沉着症:诊断难题
Q4 Medicine Pub Date : 2024-04-23 DOI: 10.1016/j.opresp.2024.100330
Anna Michela Gaeta , Adrián Nogales Moro , Dita Kopecna , Diego Tomás Vázquez Guile , Mario Virgilio Di Campli , Manuel Martínez Pérez
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引用次数: 0
期刊
Open Respiratory Archives
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