JAAD International最新文献

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Gastrointestinal comorbidities in patients with acne vulgaris: A population-based retrospective study 寻常型痤疮患者的胃肠道合并症：一项基于人群的回顾性研究

JAAD International

Pub Date : 2024-09-27 DOI: 10.1016/j.jdin.2024.08.022

Yu-Wen Chen MD , Chun-Ying Wu MD, PhD , Yi-Ju Chen MD, PhD

Background

The gut-skin-brain axis has been long postulated in acne vulgaris. Few studies focused on bowel habits in patients with acne vulgaris have yielded controversial results.

Objectives

To examine the relationship between acne vulgaris and gastrointestinal comorbidities.

Methods

We conducted a nationwide case-control study using data from the Taiwan National Health Insurance Research Database spanning the years 1997 to 2013. Acne vulgaris and the control group were stratified by age, and we examined the association of gastrointestinal comorbidities across different age, sex, and antibiotic use through conditional logistic regression analysis.

Results

A total of 185,491 patients with acne vulgaris were identified. The primary demographic for acne vulgaris comprised adolescents, followed by adult-onset groups, with a female predominance observed across all age subgroups. Patients with acne vulgaris exhibited a significantly elevated risk of developing gastrointestinal comorbidities, including peptic ulcers, irritable bowel syndrome, gastroenteritis, gastroesophageal reflux disease, and constipation. This increased risk was particularly notable in patients aged ≥12 years, and those with moderate-to-severe acne.

Limitations

Miscoding and misclassification might have occurred.

Conclusions

Patients with Acne vulgaris have higher risks of gastrointestinal comorbidities. For patients with moderate-to-severe acne, gastroenterology specialty consultation may be warranted.

背景长期以来，人们一直认为肠道-皮肤-大脑轴与寻常型痤疮有关。方法我们利用台湾国民健康保险研究数据库中 1997 年至 2013 年的数据，开展了一项全国范围的病例对照研究。我们对寻常性痤疮患者和对照组进行了年龄分层，并通过条件逻辑回归分析研究了不同年龄、性别和抗生素使用情况下胃肠道合并症的相关性。寻常型痤疮的主要发病人群是青少年，其次是成人发病人群，在所有年龄分组中均以女性为主。寻常型痤疮患者罹患消化性溃疡、肠易激综合征、肠胃炎、胃食管反流病和便秘等胃肠道合并症的风险明显升高。这种风险的增加在年龄≥12岁的患者和中重度痤疮患者中尤为明显。结论寻常型痤疮患者患胃肠道合并症的风险较高。对于中重度痤疮患者，可能需要进行胃肠病专科会诊。

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引用次数: 0

Global epidemiology of telogen effluvium after the COVID-19 pandemic: A systematic review and modeling study COVID-19大流行后毛发脱落症的全球流行病学：系统回顾与模型研究

JAAD International

Pub Date : 2024-09-24 DOI: 10.1016/j.jdin.2024.08.018

Jae Joon Jeon MD , You Hyun Kim MD , Hyunjun Kang , Min Chul Ha MD , Seung-Won Jung MD , Hyunsoo Son , Myung Ha Kim BA , Won-Soo Lee MD, PhD , Solam Lee MD, PhD

引用次数: 0

Transparency and sponsored content in social media: Considerations for dermatologists 社交媒体中的透明度和赞助内容：皮肤科医生的注意事项

JAAD International

Pub Date : 2024-09-24 DOI: 10.1016/j.jdin.2024.08.004

Cassidy Nguyen BS, Fatima Khan BS, Lia E. Gracey MD, PhD

引用次数: 0

Fracture risk in linear morphea-affected limbs: A pilot retrospective study of adult patients 受线性红斑影响肢体的骨折风险：一项针对成年患者的试点回顾性研究

JAAD International

Pub Date : 2024-09-21 DOI: 10.1016/j.jdin.2024.08.019

Maha Kazmi BS , Katharina Shaw MD , Winnie Fan BS , Bianca Obiakor BS , Ruth Ann Vleugels MD, MPH, MBA , Anna Haemel MD

引用次数: 0

Knowledge, attitude, and practice of Malagasy pharmacy staff regarding the use of topical corticosteroids in children with atopic dermatitis 马达加斯加药剂师对特应性皮炎患儿使用外用皮质类固醇激素的认识、态度和做法

JAAD International

Pub Date : 2024-09-16 DOI: 10.1016/j.jdin.2024.08.017

Fandresena Arilala Sendrasoa MD, Jonah Mamitiana Rakotoniaina MD, Lala Soavina Ramarozatovo MD, Fahafahantsoa Rapelanoro Rabenja MD

引用次数: 0

Association between rosacea and increased cardiovascular risk factors: A case-control study using the DataDerm database 红斑痤疮与心血管风险因素增加之间的关系：利用 DataDerm 数据库进行的病例对照研究

JAAD International

Pub Date : 2024-09-16 DOI: 10.1016/j.jdin.2024.08.014

Divija Sharma BA , Angel D. Pagan MD , Stella A. Caldas MD , Joel Correa da Rosa PhD , Arik Aninos BS, MSc , Benjamin Ungar MD

引用次数: 0

Effectiveness of a video-based intervention in improving skin cancer risk awareness and preventative behaviors among a diverse population of solid organ transplant recipients 以视频为基础的干预措施在提高不同实体器官移植受者的皮肤癌风险意识和预防行为方面的效果

JAAD International

Pub Date : 2024-09-16 DOI: 10.1016/j.jdin.2024.08.016

Neha Parvathala BS , Ritika Saranath MD , Yasaman Pedram BS , Alison Ly BS , Autumn Boutin BS , Jacob Gomez MD , Shannon Wong-Michalak MD , Braulio Fernandez MD , Renee Haughton MD , Cassidy Hernandez-Tamayo MPH , Jack Rodman MPH , Andrew Kwong MD , Binh Ngo MD , Jenny Hu MD , Iris Ahronowitz MD

引用次数: 0

Identification of activating hotspot mutations in acrochordons through next-generation sequencing 通过下一代测序鉴定尖头蛇的激活热点突变

JAAD International

Pub Date : 2024-09-16 DOI: 10.1016/j.jdin.2024.08.011

Justin L. Jia MD, MS , Jennifer Y. Wang MD , Warren H. Chan MD, MS , Julien Lanoue MD , Hanh Do BA , Kerri E. Rieger MD, PhD , S. Tyler Hollmig MD , Kavita Y. Sarin MD, PhD

引用次数: 0

The global reach of artificial intelligence in atopic dermatitis: The quality and reliability of ChatGPT responses in 8 languages 人工智能在特应性皮炎领域的全球应用：8种语言的ChatGPT回复的质量和可靠性

JAAD International

Pub Date : 2024-09-15 DOI: 10.1016/j.jdin.2024.08.013

Pranvera Sulejmani MD, MS , Olivia Negris MD, MA , Valeria Aoki MD, PhD , Helène Aubert MD , Chia-Yu Chu MD, PhD , Mette Deleuran MD , May El Hachem MD , Lawrence Eichenfield MD , Ana Mosca MD , Raquel Leão Orfali MD, PhD , Marketa Saint Aroman MD , Jean-Francois Stalder MD , Alain Taieb MD , Antonio Torrelo MD , David Troya MA , Magdalena Trzeciak MD, PhD , Christian Vesttergaard MD , Andreas Wollenberg MD , Peter Lio MD

引用次数: 0

Chronic disease associated with bullous pemphigoid risk: A systematic review and meta-analysis 与大疱性类天疱疮风险相关的慢性疾病：系统回顾与荟萃分析

JAAD International

Pub Date : 2024-09-07 DOI: 10.1016/j.jdin.2024.08.010

Noppachai Siranart MD , Yanisa Chumpangern MD , Somkiat Phutinart MD , Patavee Pajareya MD , Rinrada Worapongpaiboon MD , Chanissara Winson MD , Charat Thongprayoon MD , Wisit Cheungpasitporn MD

Background

Bullous pemphigoid (BP) is a chronic autoimmune blistering disease prevalent in the elderly, often accompanied by renal comorbidities. Immune dysregulation can lead to secondary BP and increased mortality rates in those already diagnosed.

Methods

A literature review identified studies on the association between kidney disease and other comorbidities with BP. Pooled effect estimates were analyzed utilizing a random-effects model.

Objective

To assess comorbidity risks with BP and determine mortality risk among BP patients with comorbidities.

Results

Analysis included 45,323 BP patients from 49 studies. Kidney diseases were significantly linked to higher BP incidence (subdistribution hazard ratio 1.51, 95% CI: 1.10-2.07) and increased mortality (hazard ratio 1.62, 95% CI: 1.13-2.32). Cerebrovascular diseases, dementia, and diabetes also showed significant associations with both increased BP incidence and mortality (P < .05). However, cardiovascular diseases and malignancy were only associated with increased mortality among BP patients (P < .001) without affecting BP incidence (P = .785 and P = .792, respectively).

Limitation

The study comprises mostly case-control, prospective, and retrospective observational studies, alongside data heterogeneity.

Conclusion

This study reveals the association of several chronic conditions, including kidney diseases, with BP, contributing to elevated mortality rates. The findings emphasize the importance of management targeting both BP and associated comorbidities to improve patient outcomes.

背景大疱性类天疱疮（Bullous pemphigoid，BP）是一种常见于老年人的慢性自身免疫性水疱病，通常伴有肾脏合并症。免疫失调可导致继发性大疱性类天疱疮，并增加已确诊患者的死亡率。方法文献综述确定了肾脏疾病和其他合并症与大疱性类天疱疮之间关系的研究。利用随机效应模型分析了汇总效应估计值。结果分析纳入了 49 项研究中的 45,323 名血压患者。肾脏疾病与较高的血压发病率（亚分布危险比 1.51，95% CI：1.10-2.07）和死亡率增加（危险比 1.62，95% CI：1.13-2.32）有明显联系。脑血管疾病、痴呆症和糖尿病也与血压升高和死亡率升高有显著关联（P < .05）。该研究主要包括病例对照研究、前瞻性研究和回顾性观察研究，同时还存在数据异质性。研究结果强调了针对血压和相关合并症进行管理以改善患者预后的重要性。

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