Pub Date : 2024-09-07DOI: 10.1016/j.jdin.2024.08.007
Samir Kamat MD , Michael Auten MA , Angela Crotty MD , Curtis L. Hardy DO , Vikas Shrivastava MD , Chad Hivnor MD
{"title":"Dermatologic priorities and considerations when caring for military service members on a global scale","authors":"Samir Kamat MD , Michael Auten MA , Angela Crotty MD , Curtis L. Hardy DO , Vikas Shrivastava MD , Chad Hivnor MD","doi":"10.1016/j.jdin.2024.08.007","DOIUrl":"10.1016/j.jdin.2024.08.007","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"17 ","pages":"Pages 155-157"},"PeriodicalIF":0.0,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142434217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-07DOI: 10.1016/j.jdin.2024.07.018
Nadia Shobnam MD, Grace Ratley MSPH, Jordan Zeldin BS, Manoj Yadav PhD, Ian A. Myles MD, MPH
Objective
Herein, we aimed to summarize the evidence-base for these interventions with a focus on the role of specific chemicals in driving AD.
Methods
A narrative review of nonprescription mitigation strategies in AD was conducted.
Results
We identified avoidance strategies for the various routes of exposure such as air pollution, water contamination, or inclusion in home goods, skin care products, and cleansers. Evidence for and against dietary modification and emollient use as primary prevention were also elucidated. To remember these interventions we propose a mnemonic, HELPSS AD: Home decor, Emollients, Laundering, Probiotics, Soaks, Social support, Air quality, and Diet.
Limitations
Each of these categories presents nuanced molecular differences that must be considered. For example, probiotic responses vary by the specific species while home products and pollution must be analyzed by the specific toxins.
Conclusion
Although the interventions discussed lack the level of evidence required for inclusion into formal guidelines, awareness of these approaches may offer aid to, and build trust with, patients and caregivers.
{"title":"Environmental and behavioral mitigation strategies for patients with atopic dermatitis","authors":"Nadia Shobnam MD, Grace Ratley MSPH, Jordan Zeldin BS, Manoj Yadav PhD, Ian A. Myles MD, MPH","doi":"10.1016/j.jdin.2024.07.018","DOIUrl":"10.1016/j.jdin.2024.07.018","url":null,"abstract":"<div><h3>Objective</h3><div>Herein, we aimed to summarize the evidence-base for these interventions with a focus on the role of specific chemicals in driving AD.</div></div><div><h3>Methods</h3><div>A narrative review of nonprescription mitigation strategies in AD was conducted.</div></div><div><h3>Results</h3><div>We identified avoidance strategies for the various routes of exposure such as air pollution, water contamination, or inclusion in home goods, skin care products, and cleansers. Evidence for and against dietary modification and emollient use as primary prevention were also elucidated. To remember these interventions we propose a mnemonic, HELPSS AD: Home decor, Emollients, Laundering, Probiotics, Soaks, Social support, Air quality, and Diet.</div></div><div><h3>Limitations</h3><div>Each of these categories presents nuanced molecular differences that must be considered. For example, probiotic responses vary by the specific species while home products and pollution must be analyzed by the specific toxins.</div></div><div><h3>Conclusion</h3><div>Although the interventions discussed lack the level of evidence required for inclusion into formal guidelines, awareness of these approaches may offer aid to, and build trust with, patients and caregivers.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"17 ","pages":"Pages 181-191"},"PeriodicalIF":0.0,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Demographics and lifestyle factors of patients with hidradenitis suppurativa: An All of Us database analysis","authors":"Gaurav N. Pathak PharmD , Timothy Makkar MD , Suraj S. Pathak BS , Shazli Razi MD , Cindy Wassef MD , Babar Rao MD","doi":"10.1016/j.jdin.2024.08.002","DOIUrl":"10.1016/j.jdin.2024.08.002","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"17 ","pages":"Pages 67-70"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142357904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-02DOI: 10.1016/j.jdin.2024.08.006
Yuki M.F. Andersen MD, PhD , Johan Sieborg MSc , Lea Nymand MSc , Tiago Torres MD, PhD , Andrea Chiricozzi MD , Simon Francis Thomsen MD, PhD, DMSc , Jacob P. Thyssen MD, PhD, DMSc , Alexander Egeberg MD, PhD, DMSc
Background
Oral Janus kinase inhibitors (JAKis) have black-box warnings of infections, cancer risk, and cardiovascular and venous thromboembolic events. They may be used off-label for chronic hand eczema (CHE).
Objectives
Assess the prevalence of risk factors potentially impacting oral JAKi safety in CHE patients.
Methods
In the Danish Skin Cohort, CHE patients were examined for risk factors affecting oral JAKi use at baseline and followed for 12 months. Data were collected through register linkage (eg, cancer history) and through patient interviews (eg, smoking habits).
Results
Of 941 adults with CHE (66.2% women; mean age 55.5 [SD 13.3] years), 768 (81.6%) patients had at least one risk factor potentially impacting oral JAKi use, of which 682 (72.5%) had nonmodifiable risk factors. Most common risk factors were current or former heavy smoking (62.8%, n = 591), obesity (28.1%, n = 264), hypercholesterolemia (21.5%, n = 202), and hypertension (18.8%, n = 177). Among patients without any risk factors at baseline (n = 173), 20.2% (n = 35) developed ≥1 risk factor during the following 12 months.
Limitations
Certain risk factors may be underreported.
Conclusion
Most CHE patients have risk factors limiting appropriateness of oral JAKi use. Health care providers should assess risk factors in their patients when choosing treatment for CHE.
{"title":"Risk factors that limit use of oral JAK inhibitors in chronic hand eczema: Findings from the Danish Skin Cohort","authors":"Yuki M.F. Andersen MD, PhD , Johan Sieborg MSc , Lea Nymand MSc , Tiago Torres MD, PhD , Andrea Chiricozzi MD , Simon Francis Thomsen MD, PhD, DMSc , Jacob P. Thyssen MD, PhD, DMSc , Alexander Egeberg MD, PhD, DMSc","doi":"10.1016/j.jdin.2024.08.006","DOIUrl":"10.1016/j.jdin.2024.08.006","url":null,"abstract":"<div><h3>Background</h3><div>Oral Janus kinase inhibitors (JAKis) have black-box warnings of infections, cancer risk, and cardiovascular and venous thromboembolic events. They may be used off-label for chronic hand eczema (CHE).</div></div><div><h3>Objectives</h3><div>Assess the prevalence of risk factors potentially impacting oral JAKi safety in CHE patients.</div></div><div><h3>Methods</h3><div>In the Danish Skin Cohort, CHE patients were examined for risk factors affecting oral JAKi use at baseline and followed for 12 months. Data were collected through register linkage (eg, cancer history) and through patient interviews (eg, smoking habits).</div></div><div><h3>Results</h3><div>Of 941 adults with CHE (66.2% women; mean age 55.5 [SD 13.3] years), 768 (81.6%) patients had at least one risk factor potentially impacting oral JAKi use, of which 682 (72.5%) had nonmodifiable risk factors. Most common risk factors were current or former heavy smoking (62.8%, <em>n</em> = 591), obesity (28.1%, <em>n</em> = 264), hypercholesterolemia (21.5%, <em>n</em> = 202), and hypertension (18.8%, <em>n</em> = 177). Among patients without any risk factors at baseline (<em>n</em> = 173), 20.2% (<em>n</em> = 35) developed ≥1 risk factor during the following 12 months.</div></div><div><h3>Limitations</h3><div>Certain risk factors may be underreported.</div></div><div><h3>Conclusion</h3><div>Most CHE patients have risk factors limiting appropriateness of oral JAKi use. Health care providers should assess risk factors in their patients when choosing treatment for CHE.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"17 ","pages":"Pages 61-66"},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142357911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-02DOI: 10.1016/j.jdin.2024.08.003
Vraj K. Shah BS , Rajiv I. Nijhawan MD
{"title":"Risk of multiple primary cancers in patients with atypical fibroxanthoma/pleomorphic dermal sarcoma: A SEER analysis","authors":"Vraj K. Shah BS , Rajiv I. Nijhawan MD","doi":"10.1016/j.jdin.2024.08.003","DOIUrl":"10.1016/j.jdin.2024.08.003","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"17 ","pages":"Pages 51-52"},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142357908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.jdin.2024.07.027
Eddy M. Zitha MSc, MD , Ogheneochuko U. Oputu PhD , Sthomo Mevana ND, BTECH , Bukiwe Thwala MPH , Lovemore Mapahla MSc , Aneliswa Mpungose BCMP , Thuraya Isaacs MD, MFamMed, MMed , Jonny Peter MD, PhD , Rannakoe J. Lehloenya BSc, MD , Nonhlanhla P. Khumalo MD, PhD
{"title":"Patients with severe cutaneous adverse drug reactions have extremely high hair cortisol concentrations that do not correlate with the presence of depression","authors":"Eddy M. Zitha MSc, MD , Ogheneochuko U. Oputu PhD , Sthomo Mevana ND, BTECH , Bukiwe Thwala MPH , Lovemore Mapahla MSc , Aneliswa Mpungose BCMP , Thuraya Isaacs MD, MFamMed, MMed , Jonny Peter MD, PhD , Rannakoe J. Lehloenya BSc, MD , Nonhlanhla P. Khumalo MD, PhD","doi":"10.1016/j.jdin.2024.07.027","DOIUrl":"10.1016/j.jdin.2024.07.027","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"17 ","pages":"Pages 163-166"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.jdin.2024.08.005
Jeffrey N. Li MD, Ryan J. Scheinkman MEng, Brian W. Morrison MD
{"title":"Biopsy-proven diagnoses associated with monodactylous longitudinal nail plate change in a diverse patient population: A retrospective cross-sectional study","authors":"Jeffrey N. Li MD, Ryan J. Scheinkman MEng, Brian W. Morrison MD","doi":"10.1016/j.jdin.2024.08.005","DOIUrl":"10.1016/j.jdin.2024.08.005","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"17 ","pages":"Pages 58-60"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142357903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-31DOI: 10.1016/j.jdin.2024.07.025
Lillian McCampbell BS , David Jun Fei-Zhang BA , Daniel Chelius MD , Ling-Lun Bob Hsia MD , Jeffrey Rastatter MD , Anthony Sheyn MD
{"title":"Social vulnerability and outcomes of head and neck cutaneous squamous cell carcinoma: A retrospective cohort study","authors":"Lillian McCampbell BS , David Jun Fei-Zhang BA , Daniel Chelius MD , Ling-Lun Bob Hsia MD , Jeffrey Rastatter MD , Anthony Sheyn MD","doi":"10.1016/j.jdin.2024.07.025","DOIUrl":"10.1016/j.jdin.2024.07.025","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"17 ","pages":"Pages 48-50"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142357909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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